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Publication numberUS3340873 A
Publication typeGrant
Publication dateSep 12, 1967
Filing dateMay 13, 1966
Priority dateMay 13, 1966
Publication numberUS 3340873 A, US 3340873A, US-A-3340873, US3340873 A, US3340873A
InventorsSolowey Ida
Original AssigneeSolowey Ida
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Compartmented medical container having a rupturable diaphragm between compartments
US 3340873 A
Abstract  available in
Previous page
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Claims  available in
Description  (OCR text may contain errors)


)24 azowgy United States Patent 3,340,873 COMPARTMENTED MEDICAL CONTAINER HAV- ING A RUPTURABLE DIAPHRAGM BETWEEN COMPARTMENTS Ida Solowey, P.0. Box 34, Fresh Meadows Station,

Flushing, N.Y. 11365 Filed May 13, 1966, Ser. No. 549,913 1 Claim. (Cl. 128-272) My invention is directed toward a hypodermic syringe which can contain two or more medicinal ingredients which are mixed only 'at the time of injection and in addition relates to bottles or vials containing two or more medicinal ingredients which are held isolated from each other until mixing is desired.

It is an object of my invention to provide a new and improved syringe of the character indicated.

Another object is to provide a new and improved medicinal vial of the character indicated.

Still another object is to provide a new and improved medicinal bottle of the character indicated.

All of the foregoing and still further objects and advantages of my invention will now be explained with reference both to this specification and to the drawings wherein:

FIGURE 1 is a perspective view of my syringe;

FIGURE 2 is a cross sectional view of a modification thereof;

FIGURE 3 is a detail view of a portion of the syringe after an injection has been given;

FIGURE 4 is a cross sectional view of another modification;

FIGURE 5 is a cross sectional view of my bottle;

FIGURES 6 and 7 are partial sectional views of a further modification.

Referring now to FIGURE 1, there is shown a hypodermic syringe having a barrel 10 with an open end 12 which accommodates a plunger 14. Barrel 10 has a tip 16 at the other end arranged for hypodermic needle attachment. Tip 16 has the conventional small orifice through which the medicine ejected from the barrel flows into the needle, and when not in use the tip is sealed by cap 18.

In use, the portion of the barrel adjacent tip 16 is filled with a first medicinal ingredient either in powder form (to which liquid is added) or in liquid form. A hollow rubber cylinder 20 having a diaphragm of very thin rubber 22 is then press fitted snugly into the barrel until the diaphragm just touches the top of the liquid level of the first ingredient. The portion of the barrel adjacent the other side of the diaphragm and extending toward the open end is then filled with a second ingredient. The plunger is inserted to rest on top of the second or top layer ingredient. As the operator presses the plunger arm 24, the head 26 of the plunger (which is contoured to conform to the inside of cylinder 20) moves downward into the second ingredient, and the pressure causes a ruptured diaphragm 22 and permits the two ingredients to mix. Thereafter, the head 26 and shoulder engages the cylinder and the head and the cylinder move downward together toward the tip ejecting the mixture thru the syringe.

To prevent the plunger 14 from slipping out, a stop 14a can be provided at the open end 12, as seen in FIG- URE 2.

FIGURE 4 shows a vial having an upper chamber 30 containing one ingredient, a lower chamber 32 having a second ingredient, a hollow section 34 open at both ends interconnecting these chambers. A rubber cylinder 20 having a diaphragm 22 is fitted in section 34. When a rubber plunger 36 in the top of the chamber 30 is depressed, the diaphragm is ruptured and the ingredients are mixed. A conventional syringe can then be filled in conventional manner by inserting the hypodermic needle through plunger 36 into the chamber. A sharp ridge 23 is provided under diaphragm 22 to help puncture the diaphragm.

FIGURE 5 shows an arrangement similar to FIG- URE 4, except that the top of chamber 30 carries a screwon cover 40 having a hole 42 through which a portion of a plunger 44 extends. In this case, the plunger cannot go through the cover and the plunger is reciprocated through the cover 40 to generate pressure on the diaphragm. The diaphragm 22 of the above said devices can be fabricated from any suitable thin flexible material.

In FIGURES 6 and 7 a diaphragm 40 is used which is cup shaped but includes a relatively thin flexible band 41 which is normally spaced from barrel 10. When the plunger 14 is depressed towards the diaphragm the band 41 expands radially into sealing engagement with barrel 10 because of the increase in pressure. Thus the diaphragm cup will cling more firmly to the barrel and the fluid pressure will build up more rapidly to cause a more efiective rupturing of the diaphragm.

It is to be noted that the engagement between the plunger and diaphragm and their combined further movement causes a simultaneous ejecting pressure and further mixing of the ingredients.

Having thus described my invention, I claim as new and desire to secure by Letters Patent:

A medical mixing container having upper and lower chambers sealingly separated by a thin rupturable diaphragm transversely mounted sealingly and longitudinally movable within the container, said diaphragm being in the form of an expandable cylinder having a circumferential barrel and a transverse bottom, said barrel having a portion normally spaced from the container and having an upper shoulder, in combination with a plunger longitudinally movable within one of said chambers and being contoured to fit snugly within the said chambers, including ingredients which are mixed when the diaphragm is ruptured, said plunger having surfaces adapted to sealingly engage the barrel, bottom and shoulder of the diaphragm, whereby axial movement of the plunger will first cause the barrel to expand towards the container, whereby complete engagement with the wall being then eifected when the plunger has entered the cylinder to contact the barrel and snap the said portion against the container, whereby the diaphragm bottom is ruptured during the axial movement of the plunger, further movement of the plunger causing the plunger surfaces to sealingly engage the diaphragm thereby moving the diaphragm axially, including means mounted on the end of the container opposite the plunger adapted to receive a hypodermic needle and wherein the plunger extends through an open end of the container having a perforated closure wherein said closure functions as a stop to prevent complete removal of the plunger from the container.

References Cited UNITED STATES PATENTS 1,943,120 1/ 1934 Kabnick 128-218 2,590,900 4/ 1952 Sommerstein 128272 2,591,706 4/1952 Lockhart 128-218 2,705,956 4/ 1955 McLaughlin 128-272 FOREIGN PATENTS 961,289 4/ 1957 Germany.

RICHARD A. GAUDET, Primary Examiner.


Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1943120 *May 21, 1930Jan 9, 1934Stuart KabnickHypodermic syringe
US2590900 *Mar 23, 1949Apr 1, 1952Cwi SommersteinAmpoule
US2591706 *Sep 29, 1950Apr 8, 1952Compule CorpPlural-compartment admixing hypodermic syringe ampoule for segregated storage of ingredients of liquid medicinal solutions and therapeutic preparations
US2705956 *Mar 10, 1952Apr 12, 1955Mclaughlin Howard JMeans of administering procaine and like preparations
DE961289C *Oct 5, 1952Apr 4, 1957Dr Med Dent Wilhelm EisenbergZur getrennten Aufbewahrung und zum Mischen der Bestandteile eines zu verspritzendenMittels ausgebildete zweikammerige Ampulle
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3870147 *Apr 19, 1973Mar 11, 1975Wolf Geraete GmbhContainer for storage and preparation of a plant protective material containing at least two components
US4159570 *Oct 31, 1977Jul 3, 1979Dentipressions IncorporatedDisposable mixing syringe
US4191254 *Jan 16, 1978Mar 4, 1980Baughman Kenneth EApparatus and method for plugging voids in a ground stratum
US4693706 *Aug 11, 1986Sep 15, 1987Mark L. AndersonTwo compartment mixing syringe
US4983164 *Apr 12, 1988Jan 8, 1991Astra Meditec AbAutomatic two-chamber injector
US5002206 *Oct 25, 1989Mar 26, 1991Merck & Co., Inc.Double tip drug dispensing and metering device
US5137528 *Nov 26, 1990Aug 11, 1992Crose Virginia WAmpoule for administering a liquid local anaesthetic
US5196001 *Mar 5, 1991Mar 23, 1993Ti KaoDevices and methods for preparing pharmaceutical solutions
US5217433 *May 24, 1991Jun 8, 1993Merck & Co., Inc.Medication container for mixing two components
US5322800 *Aug 13, 1993Jun 21, 1994The United States Of America As Represented By The Secretary Of The InteriorMethod and device for safely preserving aqueous field samples using acid or base
US6372270 *May 16, 2000Apr 16, 2002Sean P. DennyDrink mix apparatus for making personal quantities of beverage
US6419414Apr 20, 2001Jul 16, 20023M Innovative Properties CompanyContainer for multiple-component compositions
US6543612May 21, 2001Apr 8, 20033M Innovative Properties CompanyContainer for compositions made of two or more components
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US20050113768 *Jun 15, 2004May 26, 2005Carlos PatricksonPain-alleviating injection needle
US20090206084 *Mar 24, 2006Aug 20, 2009Ipifini, Inc.Programmable liquid containers
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WO2003022696A1 *Sep 10, 2002Mar 20, 2003Den-Mat CorporationUnit-dose packaging system
WO2006118697A3 *Mar 24, 2006Jan 25, 2007IpifiniProgrammable liquid containers
WO2011071463A1 *Oct 12, 2010Jun 16, 2011Aleksandr Vladimirovich MerenkovContainer, container for packaging and storing two components, and container manufacturing method
WO2014180902A1 *May 7, 2014Nov 13, 2014Auxin Surgery SaDevice for chemically assisted dissection
U.S. Classification604/87, 604/416, 206/219, 215/DIG.800
International ClassificationA61M5/28, A61M5/19, A61J1/00, B65D25/08, A61J1/20
Cooperative ClassificationA61M5/19, Y10S215/08, B65D25/082, A61J2001/2027, A61J2001/2041, A61M5/284, A61J1/2093
European ClassificationB65D25/08B, A61M5/28M, A61M5/19, A61J1/20D