|Publication number||US3390677 A|
|Publication date||Jul 2, 1968|
|Filing date||Jul 8, 1965|
|Priority date||Jul 10, 1964|
|Also published as||DE1491804A1|
|Publication number||US 3390677 A, US 3390677A, US-A-3390677, US3390677 A, US3390677A|
|Original Assignee||Jacquez Razimbaud|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (98), Classifications (13)|
|External Links: USPTO, USPTO Assignment, Espacenet|
J. RAZIMBAUD 3,390,677 DEVICE FOR PERFUSION OF STERILE SOLUTIONS AND July 2, 1968 TRANSFUSION OF BLOOD Filed July 8 1965 United States Patent 81,56 3 Claims. (Cl. 128-414) ABSTRACT OF THE DISCLOSURE A perfusion and transfusion device with a sterile solution or blood storage receptacle, a chamber connected to the outlet of said storage receptacle and having a pierceable transverse wall in the course of said outlet, and a dispensing receptacle in fluid-tight movable engagement with said chamber, formed with a hollow needle arranged to pierce said transverse wall in response to the movement of said chamber in relation to said dispensing receptacle. The relative movement of the dispensing receptacle and chamber is governed by at least one lug projecting from said chamber and engaging with a cam slot in said dispensing receptacle.
This invention relates to devices for the perfusion of sterile solutions and transfusion of blood.
The devices for this purpose commonly in use to-day comprise a storage receptacle for the blood or the sterile solution which can be pierced by a needle in a sterile housing and connected by a tube to a blood dispensing receptacle to which an injection needle can be connected by a flexible tube.
The invention is concerned with an improved device of that general kind which consists in forming the dispensing receptacle and the needle as a unit which can be stored as such, free from contamination, until required for use.
The device in accordance with the invention comprises a storage receptacle for the blood or sterile solution having a pierceable wall, a dispensing receptacle for blood or sterile solution drawn from the storage receptacle and a needle for piercing the wall of the storage receptacle and providing a passage for the flow of blood or sterile solution therethrough to the dispensing receptacle. The needle is fixed to and forms a unit with the dispensing receptacle and its piercing end is housed in a chamber depending from the storage receptacle and has a fluid-tight connection with the dispensing receptacle which allows relative movement of the two receptacles to cause the needle to pierce the storage receptacle.
In the preferred form of the invention, the wall of the needle housing chamber is engaged in an annular bore in a wall of the dispensing receptacle. In that case, the wall of the needle housing chamber can have at least one lug projecting from it into engagement with a cam slot in a part of the dispensing receptacle which converts rotary movement of the storage receptacle into axial movement. Such a cam slot can usefully have portions in which the lugs can be engaged to hold the two receptacles against relative axial movement with the needle in either of its extreme positions relatively to the storage receptacle.
The dispensing receptacle can also usefully have a removable cap, provided if desired with a blood or solution filter to which an injection needle can be connected.
An example of a sterile solution perfusing and blood transfusing device in accordance with the invention is shown in the accompanying drawings in which:
FIGURE 1 shows the device in outside elevation and FIGURE 2 is a section taken on the line II-II in FIG- URE 1; and
FIGURE 3 is a section taken on the line III-III in FIGURE 2.
The illustrated device has two main parts 1 and 8.
The part 1 which is mounted on the part 8 for movement relatively thereto comprises a lower skirted portion 2 surmounted by a part 3 of smaller diameter closed at two thirds of its height by a thin wall 4 which separates it from a blood storage receptacle 5 welded or otherwise fixed to it. These parts although shown of circular crosssection could be of polygonal cross-section.
The skirt 2 engages in an annular bore 6 in an upper extension 7 of the cylindrical or polygonal part 8 which constitutes a blood or solution dispensing receptacle.
The skirt 2 is provided at its lower end with two cylindrical diametrically opposite lugs 10 which are engaged in two cam slots 11 in the outer wall of the annular bore 6, each of these slots having a horizontal part 12 followed by a vertical part 13, an inclined part 14 and another horizontal part 15 (see FIGURE 1).
The upper end 7 of the dispensing receptacle 8 has a central bore 16 in which is fixed by adhesion, soldering or welding a hollow needle 17 the lower end of which lies within the space 9 of that receptacle and the upper end of which lies within the movable part 1. The dispensing receptacle element 8 has a reinforcing ring 18 formed with diametrically opposite notches 19 leading to the annular bore 6 so as to allow the two parts 1 and 8 to be assembled for storage.
The skirt of the part 2 has at its lower end one or more beads 20 (only one shown) providing a space which can be filled with an impermeable viscous substance 21 impregnated with bacteriostatic germicides forming a seal and a joint which is permanently smooth between the inner wall of the skirted part 2 and the inner bounding surface 6a of the annular bore 6. Even if a substantial pressure is exerted here, this viscous substance prevents any risk of contamination while ensuring perfect fluidtightness. The dispensing receptacle 8 is provided at its lower end with a removable plug 22 which can be fixed by adhesion, soldering or welding and is provided with a tubular extension 23 allowing the receptacle 9 to be connected to an injection needle by means of a flexible tube 24. If desired, the plug can be provided with a blood or solution filter 25.
The device described above is used in the following manner:
The device is available in the ready for use condition shown in FIGURE 1, that is to say, with the part 1 in the elevated position, its lower end being engaged in the annular bore 6 and the lugs 8 being engaged in the upper horizontal parts 12 of the cam slots 11. The device will have been previously sterilized either by steam under pressure or by the action of gaseous germicidal agents, and the device placed in a sterile atmosphere in a welded plastic container.
When the device is to be used, the part 1 is rotated in the direction of the arrow F (FIGURE 3) to bring the lugs 10 above the vertical parts 13 of the card slots 11 in order to enable it to be moved downwards as indicated by the arrow F1 (FIGURE 2). During this downward movement the end of the needle 17 perforates the thin wall 4 and penetrates into the blood or sterile solution storage receptacle 5 allowing the blood or sterile solution to flow out through the needle 17 into the dispensing receptacle 9. A second rotary movement is then imparted to the part 1 in the direction of the arrow F (FIGURE 3) so that the lugs 10 are brought into the lower horizontal parts 15 of the cam slots 11 to ensure locking of the part 1 in the position shown in chain lines in FIGURE 2 in which the whole of the blood or sterile solution contained in the storage receptacle 5 can flow into the dispensing receptacle 8 and thence through the flexible tube 24 to the injection needle. During these rotary and downward movements of the part 1, the viscous substance 21 ensures great smoothness of movement by acting as a lubricant. Also a fluid-tight seal between the inner -bounding wall of the part body 2 and the surface 6a of the annular bore 6 is permanently ensured because of the entrainment of a film of this sterile viscous substance over the surface 6a.
The parts of this device can be of any material which is transparent, sterilizable, neutral, rigid and non-deformable such as glass, polystyrene or Plexiglas.
What is claimed is:
1. A device for the perfusion of sterile solutions or transfusion of blood comprising a storage receptacle for the blood or sterile solution; a chamber attached to an outlet of said storage receptacle and having a pierceable wall in the course of said outlet; a dispensing receptacle being in fluid-tight connection at its input end to said chamber, said connection permitting relative movement of said chamber and said dispensing receptacle; and a needle fixedly attached to said dispensing receptacle and having its piercing end housed in said chamber whereby upon the relative movement of said chamber and said dispensing receptacle said needle pierces the wall of said chamber thereby permitting the flow of blood or sterile solution from said storage receptacle, through said chamher, said needle, and said dispensing receptacle, and out of the outlet of said dispensing receptacle, said dispensing receptacle being formed with at least one cam slot, and said chamber being formed with at least one lug projecting therefrom and engaging with the corresponding ca-m slot, whereby the direction of the relative movement of said chamber and said dispensing receptacle is controlled, said cam slot having portions in which the corresponding lug, when engaged therein, prevents relative axial movement of said chamber and said dispensing receptacle at either of the two extreme positions of said needle.
2. A device as recited in claim 1, in which a portion of said cam slot is adapted to convert rotary movement of said chamber into axial movement thereof.
3. A device for the perfusion of sterile solutions and the transfusion of blood comprising a storage receptacle for the blood or sterile solution having a pierceable wall; a chamber depending from said storage receptacle at said pierccable wall having at least one lug projecting there from; a dispensing receptacle formed with at least one cam slot adapted to receive the corresponding lug therein, said dispensing receptacle being in fluid-tight connection With said chamber, said connection permitting relative movement of said chamber and said storage receptacle as guided by said lug engaging said cam slot; and a hollow needle fixedly attached to said dispensing receptacle and having its piercing end housed in said chamber, where-by the relative movement of said chamber and said dispensing receptacle causes said needle to pierce the wall of said storage receptacle, thereby permitting the blood or sterile solution to flow from said storage receptacle through said chamber, said needle, and said dispensing receptacle, said cam slot having portions in which, when said corresponding lugs are engaged therein, relative axial movement between said chamber and said dispensing receptacle is prevented at the two extreme positions of said needle.
References Cited UNITED STATES PATENTS 3,021,841 2/1962 Burke 128214 3,127,892 4/1964 Bellamy 128-2142 3,206,073 9/1965 Scislowicz 222 FOREIGN PATENTS 1,228,983 3/1960 France. 1,282,046 12/1961 France.
DALTON L. TRULUCK, Primary Examiner.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3021841 *||Mar 14, 1957||Feb 20, 1962||Baxter Laboratories Inc||Intravenous administration equipment|
|US3127892 *||Jul 13, 1960||Apr 7, 1964||Baxter Laboratories Inc||Blood handling apparatus|
|US3206073 *||Feb 13, 1963||Sep 14, 1965||Abbott Lab||Dispensing assembly for a container and a sheath therefor|
|FR1228983A *||Title not available|
|FR1282046A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3557786 *||Jun 18, 1968||Jan 26, 1971||Abbott Lab||Administration apparatus for intravenous substances|
|US3828779 *||Dec 13, 1972||Aug 13, 1974||Ims Ltd||Flex-o-jet|
|US4265760 *||Feb 26, 1979||May 5, 1981||Becton Dickinson & Company||Device for dilution and delivery of in vivo chemicals|
|US4576211 *||May 7, 1984||Mar 18, 1986||Farmitalia Carlo Erba S.P.A.||Safety device for connection of a syringe with the mouth or opening of a bottle containing a drug or a small tube for drug delivery from the syringe|
|US4685917 *||Nov 7, 1984||Aug 11, 1987||Bieffe S.P.A.||Sterilizable valvular systems for flexible containers|
|US4759756 *||Sep 14, 1984||Jul 26, 1988||Baxter Travenol Laboratories, Inc.||Reconstitution device|
|US5566845 *||Feb 1, 1995||Oct 22, 1996||Idea Laboratories, Inc.||Container having a seal puncturing device|
|US7722577 *||Aug 16, 2005||May 25, 2010||Becton, Dickinson And Company||Bubble free—self primed IV set|
|US7867215||Apr 17, 2002||Jan 11, 2011||Carmel Pharma Ab||Method and device for fluid transfer in an infusion system|
|US7921740||Jul 20, 2007||Apr 12, 2011||Millipore Corporation||Disposable, pre-sterilized fluid receptacle sampling device|
|US7927316||Apr 25, 2003||Apr 19, 2011||Millipore Corporation||Disposable, sterile fluid transfer device|
|US7942860||Mar 16, 2007||May 17, 2011||Carmel Pharma Ab||Piercing member protection device|
|US7975733 *||May 8, 2007||Jul 12, 2011||Carmel Pharma Ab||Fluid transfer device|
|US8029747||Jun 13, 2007||Oct 4, 2011||Carmel Pharma Ab||Pressure equalizing device, receptacle and method|
|US8038663 *||Apr 29, 2010||Oct 18, 2011||Becton, Dickinson And Company||Bubble free-self primed IV set|
|US8075550||Jul 1, 2008||Dec 13, 2011||Carmel Pharma Ab||Piercing member protection device|
|US8162013||May 21, 2010||Apr 24, 2012||Tobias Rosenquist||Connectors for fluid containers|
|US8225826||May 19, 2011||Jul 24, 2012||Carmel Pharma Ab||Fluid transfer device|
|US8282608||Sep 7, 2007||Oct 9, 2012||Becton, Dickinson And Company||Self priming intravenous delivery system|
|US8287513||Sep 11, 2007||Oct 16, 2012||Carmel Pharma Ab||Piercing member protection device|
|US8328772||Jan 21, 2004||Dec 11, 2012||Carmel Pharma Ab||Needle for penetrating a membrane|
|US8336587||Apr 23, 2012||Dec 25, 2012||Carmel Pharma Ab||Connectors for fluid containers|
|US8381776||Apr 6, 2011||Feb 26, 2013||Carmel Pharma Ab||Piercing member protection device|
|US8382711||Dec 29, 2010||Feb 26, 2013||Baxter International Inc.||Intravenous pumping air management systems and methods|
|US8480646||Nov 20, 2009||Jul 9, 2013||Carmel Pharma Ab||Medical device connector|
|US8517998||Apr 22, 2011||Aug 27, 2013||Emd Millipore Corporation||Disposable, sterile fluid transfer device|
|US8523838||Dec 10, 2009||Sep 3, 2013||Carmel Pharma Ab||Connector device|
|US8539988||Dec 15, 2009||Sep 24, 2013||Emd Millipore Corporation||Device for the transfer of a medium|
|US8544497||Oct 12, 2010||Oct 1, 2013||Emd Millipore Corporation||Fluid transfer device and system|
|US8545475||Jan 7, 2005||Oct 1, 2013||Carmel Pharma Ab||Coupling component for transmitting medical substances|
|US8549935||Sep 24, 2008||Oct 8, 2013||Emd Millipore Corporation||Disposable, pre-sterilized fluid receptacle sampling device|
|US8562572||Feb 8, 2006||Oct 22, 2013||Emd Millipore Corporation||Disposable, sterile fluid transfer device|
|US8562583||Mar 26, 2002||Oct 22, 2013||Carmel Pharma Ab||Method and assembly for fluid transfer and drug containment in an infusion system|
|US8579871||Oct 20, 2006||Nov 12, 2013||Emd Millipore Corporation||Disposable, sterile fluid transfer device|
|US8622985||Jun 13, 2007||Jan 7, 2014||Carmel Pharma Ab||Arrangement for use with a medical device|
|US8646342||Aug 31, 2010||Feb 11, 2014||Emd Millipore Corporation||Disposable, pre-sterilized fluid receptacle sampling device|
|US8657803||Jun 13, 2007||Feb 25, 2014||Carmel Pharma Ab||Device for providing fluid to a receptacle|
|US8690120 *||Nov 13, 2008||Apr 8, 2014||Emd Millipore Corporation||Fluid transfer device|
|US8790330||Dec 15, 2008||Jul 29, 2014||Carmel Pharma Ab||Connection arrangement and method for connecting a medical device to the improved connection arrangement|
|US8827978||Sep 17, 2007||Sep 9, 2014||Carmel Pharma Ab||Bag connector|
|US8915264||Jul 31, 2013||Dec 23, 2014||Emd Millipore Corporation||Fluid transfer device and system|
|US8919365||Aug 1, 2013||Dec 30, 2014||Emd Millipore Corporation||Fluid transfer device and system|
|US8926583||Sep 12, 2012||Jan 6, 2015||Carmel Pharma Ab||Piercing member protection device|
|US8974414||Feb 13, 2013||Mar 10, 2015||Becton, Dickinson And Company||IV drip chamber with filter and bottom reservoir|
|US8985843 *||Oct 29, 2011||Mar 24, 2015||Baby Bullet, LLC||System and method for enhanced preparation and storage of homemade baby food|
|US9028779||Dec 15, 2009||May 12, 2015||Emd Millipore Corporation||Device for the transfer of a medium|
|US9039672||Aug 23, 2013||May 26, 2015||Carmel Pharma Ab||Coupling component for transmitting medical substances|
|US9084858||Feb 21, 2013||Jul 21, 2015||Baxter International Inc.||Intravenous pumping air management systems and methods|
|US9120585||Apr 13, 2015||Sep 1, 2015||Emd Millipore Corporation||Device for the transfer of a medium|
|US9150825||Sep 20, 2013||Oct 6, 2015||Emd Millipore Corporation||Device for the transfer of a medium|
|US9168203||May 19, 2011||Oct 27, 2015||Carmel Pharma Ab||Connectors for fluid containers|
|US9279100||Aug 28, 2013||Mar 8, 2016||Emd Millipore Corporation||Device for the transfer of a medium|
|US9296983||Sep 20, 2013||Mar 29, 2016||Emd Millipore Corporation||Device for the transfer of a medium|
|US9309020||Nov 26, 2013||Apr 12, 2016||Carmel Pharma Ab||Device for providing fluid to a receptacle|
|US9482351||Aug 21, 2013||Nov 1, 2016||Emd Millipore Corporation||Disposable, sterile fluid transfer device|
|US9724269 *||Nov 27, 2013||Aug 8, 2017||Becton Dickinson and Company Ltd.||Connector for fluid communication|
|US20030199847 *||Apr 17, 2002||Oct 23, 2003||Roger Akerlund||Method and device for fluid transfer in an infusion system|
|US20050016620 *||Apr 25, 2003||Jan 27, 2005||Stephen Proulx||Disposable, sterile fluid transfer device|
|US20060142730 *||Feb 8, 2006||Jun 29, 2006||Millipore Corporation||Disposable, sterile fluid transfer device|
|US20060189937 *||Aug 16, 2005||Aug 24, 2006||Becton Dickinson And Company||Bubble free - self primed IV set|
|US20060276759 *||Jan 21, 2004||Dec 7, 2006||Peter Kinast||Needle for penetrating a membrane|
|US20080022785 *||Jul 20, 2007||Jan 31, 2008||Furey James F||Disposable, pre-sterilized fluid receptacle sampling device|
|US20080097315 *||Sep 7, 2007||Apr 24, 2008||Becton, Dickinson And Company||Self priming intravenous delivery system|
|US20080223484 *||Mar 16, 2007||Sep 18, 2008||Carmel Pharma Ab||Piercing Member Protection Device|
|US20080277021 *||May 8, 2007||Nov 13, 2008||Petri Horppu||Fluid Transfer Device|
|US20080312633 *||Jun 13, 2007||Dec 18, 2008||Anna Ellstrom||Arrangement for use with a medical device|
|US20090019952 *||Sep 24, 2008||Jan 22, 2009||Furey James F||Disposable, pre-sterilized fluid receptacle sampling device|
|US20090057258 *||Aug 30, 2007||Mar 5, 2009||Hakan Tornqvist||Device, Sealing Member and Fluid Container|
|US20090069783 *||Sep 11, 2007||Mar 12, 2009||Anna Ellstrom||Piercing member protection device|
|US20090229671 *||Nov 13, 2008||Sep 17, 2009||Millipore Corporation||Fluid transfer device|
|US20100004602 *||Jul 1, 2008||Jan 7, 2010||Carmel Pharma Ab||Piercing Member Protection Device|
|US20100147402 *||Dec 10, 2009||Jun 17, 2010||Carmel Pharma Ab||Connector Device|
|US20100152669 *||Dec 15, 2008||Jun 17, 2010||Carmel Pharma Ab||Connection arrangement and method for connecting a medical device to the improved connection arrangement|
|US20100154569 *||Dec 15, 2009||Jun 24, 2010||Millipore Corporation||Device For The Transfer Of A Medium|
|US20100158759 *||Dec 15, 2009||Jun 24, 2010||Millipore Corporation||Device For The Transfer Of A Medium|
|US20100217229 *||Apr 29, 2010||Aug 26, 2010||Becton, Dickinson And Company||Bubble free-self primed iv set|
|US20110197989 *||Apr 22, 2011||Aug 18, 2011||Millipore Corporation||Disposable, sterile fluid transfer device|
|US20110214781 *||May 19, 2011||Sep 8, 2011||Petri Horppu||Fluid transfer device|
|US20120107469 *||Oct 29, 2011||May 3, 2012||Lenny Sands||System and method for enhanced preparation and storage of homemade baby food|
|US20140150925 *||Nov 27, 2013||Jun 5, 2014||Becton Dickinson and Company Limited||Connector for Fluid Communication|
|USD637713||May 17, 2010||May 10, 2011||Carmel Pharma Ab||Medical device adaptor|
|CN101104083B||Jul 11, 2006||Jun 22, 2011||上海康德莱企业发展集团有限公司||Double-cavity drop funnel blood transfusion device|
|CN102716032A *||Jul 2, 2012||Oct 10, 2012||重庆莱美药业股份有限公司||Thrust unit used on precession preassembling type dosing instrument|
|CN102716032B||Jul 2, 2012||Oct 1, 2014||重庆莱美药业股份有限公司||旋进预装式加药仪上使用的推动装置|
|CN102716523A *||Jul 2, 2012||Oct 10, 2012||重庆莱美药业股份有限公司||Screw-in pre-installed type medicine-charging instrument|
|CN102716523B||Jul 2, 2012||Jul 17, 2013||重庆莱美药业股份有限公司||Screw-in pre-installed type medicine-charging instrument|
|CN104902863A *||Nov 29, 2013||Sep 9, 2015||贝克顿迪金森有限公司||Connector for fluid communication|
|DE19930791A1 *||Jul 3, 1999||Jan 11, 2001||Fresenius Ag||Arretierbarer Nadeladapter|
|DE19930791B4 *||Jul 3, 1999||Feb 12, 2004||Fresenius Ag||Arretierbarer Nadeladapter|
|EP2144589A1 *||May 8, 2007||Jan 20, 2010||Carmel Pharma AB||Fluid transfer device|
|EP2144589A4 *||May 8, 2007||Jan 1, 2014||Carmel Pharma Ab||Fluid transfer device|
|EP2286870A1 *||Apr 25, 2003||Feb 23, 2011||Millipore Corporation||Disposable steam sterilisable medical valve|
|EP2292297A1 *||Apr 25, 2003||Mar 9, 2011||Millipore Corporation||Disposable steam sterilisable medical valve|
|EP3111911A1 *||May 8, 2007||Jan 4, 2017||Carmel Pharma AB||Fluid transfer device|
|WO1986001712A1 *||Aug 7, 1985||Mar 27, 1986||Baxter Travenol Laboratories, Inc.||Reconstitution device|
|WO2008115102A1 *||Mar 16, 2007||Sep 25, 2008||Carmel Pharma Ab||A piercing member protection device|
|WO2012117648A1 *||Dec 22, 2011||Sep 7, 2012||Terumo Kabushiki Kaisha||Connector assembly|
|WO2014083149A1 *||Nov 29, 2013||Jun 5, 2014||Becton Dickinson and Company Ltd.||Connector for fluid communication|
|U.S. Classification||604/414, 604/251, 222/83, 210/448|
|International Classification||A61M5/14, A61M5/162, A61M5/165|
|Cooperative Classification||A61M5/165, A61M5/14, A61M5/162|
|European Classification||A61M5/162, A61M5/14, A61M5/165|