|Publication number||US3416531 A|
|Publication date||Dec 17, 1968|
|Filing date||Jan 2, 1964|
|Priority date||Jan 2, 1964|
|Also published as||DE1491697A1|
|Publication number||US 3416531 A, US 3416531A, US-A-3416531, US3416531 A, US3416531A|
|Inventors||Edwards Miles Lowell|
|Original Assignee||Edwards Miles Lowell|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (11), Referenced by (302), Classifications (15)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Dec. 1 7, 1968 M, EDWARDS 3,416,531
CATHETER Filed Jan. 2, 1964 2 Sheets-Sheet 1 M 52 so 52 INVENTOR.
46 MILES LOWELL EDWARDS Attorney Dec. 17, 1968 M. L. EDWARDS 3,416,531
CATHETER Filed Jan. 2. 1964 l 2 Sheets-Sheet z lllll Hlll lllll lllll lllll .Hll lllll Hlll Hlll lTHl lIHl IN V EN TOR.
MILES LOWELL EDWARDS United States Patent 3,416,531 CATHETER Miles Lowell Edwards, 13191 Sandhurst Place, Santa Ana, Calif. 92705 Filed Jan. 2, 1964, Ser. No. 335,049 25 Claims. (Cl. 12s-34s ABSTRACT OF THE DISCLOSURE A catheter tube is connected with a manipulative handle. The handle carries a flexible guide tube which is insertable in the catheter tube. A bending element on the distal end of the guide tube is flexed by a pull wire which may be tensioned by a lever on the handle to bend the tip of the catheter tube. Means are provided on the handle for rotating the catheter tube and guide tube and the catheter tube contains torsional reinforcement so that it will rotate uniformly throughout its length.
This invention relates to improvements in a catheter.
It is often necessary to control the direction of a catheter as it is inserted into a tube in the body. For example, it is desirable to use a catheter in diagnosing coronary arteries by visualization with the use of a fluoroscope. A catheter, which is made opaque to X-rays, is inserted in an incision at some convenient point in an artery, for instance in the patients arm, which will lead the catheter to the aorta. Then, as the end of the catheter approaches the coronary arteries which branch from the aorta, the catheter must be guided so that it will change its direction in order to enter the desired coronary artery as its progress is observed in the fluoroscope. For this purpose, means are provided in the present catheter for bending its distal end at an angle to its direction in the aorta.
In addition to merely bending the end of the catheter tube, there exists the problem of orienting the bent end in the desired radial direction. Orienting the distal end of the catheter tube by twisting its proximal end requires a high degree of torsional rigidity in the tube. It cannot be done with facility if the catheter tube has an appreciable degree of torsional flexibility. At the same time, the tube must be quite flexible in bending in order to follow freely a curved path for some distance from the incision and then make a substantially right angle bend into a particular branch artery. A similar problem exists in guiding a catheter into various branch tubes and chambers of the body, other than blood vessels, for various purposes. The conflicting requirements of torsional rigidity and flexibility in bending are not satisfied by conventional catheter tubes where one quality can be attained only at the sacrifice of the other.
The general object of the invention is, therefore, to provide an improved catheter for the purpose described. More specifically, the object is to provide a catheter having a high degree of torsional rigidity without sacrifice of flexibility in bending. Another object is to provide a new and improved means of reinforcement for a catheter tube which has torsional rigidity with flexibility for bending. Another object is to provide an improved device for bending the end of a catheter tube. Still another object is to provide means for measuring blood pressure through a catheter tube and means for injecting and withdrawing fluids through the tube.
The present catheter is made of flexible plastic tubing having incorporated in the wall thereof a novel reinforcement having the described characteristics. The conflicting requirements of torsional rigidity with flexibility in bending are accomplished by a reinforcement of strands arranged in opposite spiral directions. In the present embodiments the reinforcement comprises a tubular braidice ing of monofilament material which is embedded in the wall of the tube but other arrangements of the spiral strands are possible. Such reinforcement causes the distal end of the tube to rotate strictly in conformity to the twisting motion imparted to the proximal end whereby when the distal end is bent it can be guided into a particular branch channel at an angle to the direction of approach. A novel bending device is also provided employing a Bowden wire control manipulable from the proximal end of the catheter tube. In this way, by observing the catheter in a fluoroscope, the distal end may be guided into a branching tube or chamber of the body in any direction around the axis of the approach tube.
The foregoing and other objects and advantages will become apparent and the invention will be better understood from thefollowing detailed description of the preferred embodiment illustrated in the accompanying drawings. Various changes may be made, however, in the details of construction and arrangement of parts and certain features may be used without others. All such modifications within the scope of the appended claims are included in the invention.
In the drawing:
FIGURE 1 is an enlarged side view of a catheter tube containing the improved reinforcement;
FIGURE 2 is a further enlarged fragmentary sectional view taken on the line 22 of FIGURE 1;
FIGURE 3 is a similar view taken on the line 33 of FIGURE 1;
FIGURE 4 is a fragmentary developed view of the reinforcement greatly enlarged;
FIGURE 5 is an enlarged cross sectional view showing the molding operation in the manufacture of the catheter tube;
FIGURE 6 is an enlarged fragmentary side view of a modification with some of the outer plastic material broken away to show the reinforcement;
FIGURE 7 is a vie-w of the bending device showing the parts in bent position in broken lines;
FIGURE 8 is an enlarged longitudinal sectional view of the distal end of the bending device in FIGURE 7;
FIGURE 9 is an enlarged view with parts in section showing the operation of the bending device in a catheter tube;
FIGURE 10 is a view of the proximal end of the bending device with parts in longitudinal section;
FIGURE 11 is a greatly enlarged longitudinal sectional view of the removable catheter bending core in FIGURE 10;
FIGURE 12 is a view taken on the line 1212 of FIGURE 11; and
FIGURE 13 is a view at approximately natural size, showing manipulation of the catheter.
In FIGURE 1 the catheter tube is designated generally by the numeral 10. On the proximal end of the tube is a conventional metal female connector fitting 11 which, according to standard practice, has a tapered bore for frictional connection with a male fitting on some instrumentality or device which is used with the tube. The distal end portion preferably tapers beginning at a point 12 to make it more slender and flexible and easier to introduce through restricted passageways and openings. The taper may terminate a short distance from the end. The tube has an end opening 13 and pairs of elongated side openings on opposite sides of the tube at to each other as indicated at 14 and 15. These openings communicate with the longitudinal passageway 16 which extends throughout the length of the catheter tube. This tapered end portion is designated at 17.
The catheter tube is made of a suitable heat working plastic, such as silicone rubber or polyvinyl chloride, and
incorporated in the wall of the tube is a spirally directed reinforcement to impart torsional rigidity without impairing the flexibility of the tube in bending. This reinforcement preferably comprises strands of a suitable monofilament material such as metal wire, nylon or Teflon. These strands are laid in opposite spiral directions and in the present embodiments are braided together. To avoid possible exposure of cut ends of the strands at the slender distal end of the tube, braiding is started in a first cylindrical layer at the proximal end of the tube and continued to the distal end where it is doubled back upon itself to form a second layer which continues back to the proximal end. This results in a double layer of braiding having an underlying layer 21 and an overlying layer 22, as shown in FIGURE 4. In order to distinguish one layer from the other, the underlying layer 21 has been drawn with heavy lines and the overlying layer 22 drawn with light lines but it is to be understood that the strands in the top layer 22 are merely continuations of the strands 21 of the bottom layer.
In making the tube, a layer of plastic material 24 is applied around a smooth surfaced mandrel or core rod 25 which has the diameter desired for the passageway 16. Then a circular braiding machine is employed to braid the strands around the plastic layer and under sufficient strand tension to cause the strands to become embedded in the plastic as the braiding takes place. Outstanding lugs on core rod 25 form the openings 14 and 15 at the distal end and, as the layer of braiding reaches these lugs, the braiding is stopped and the strands are crowded together to avoid the lugs, as shown in FIGURE 2, so that the strands will not cross these openings in the finished tube. At the distal end of the tube the braiding operation After completion of the braiding operation, the core member with its layer of plastic and two layers of reinforcement embedded therein is placed in a mold to cure or vulcanize the plastic and form a smooth surface on the exterior of the tube, completely covering the braiding. This step of the process is illustrated in FIGURE 5 where the lower mold member 30 has a semi-cylindrical cavity 31 and the upper mold member 32 has a semicylindrical cavity 33 to receive the plastic covered core member 25. The connector fitting 11 is assembled with the core member and plastic cover before the latter are placed in the mold and then when the plastic has been cured, the assembly is removed from the mold and the is reversed to proceed back toward the proximal end with the strands again under suflicient tension to embed them in the plastic layer and crowded around the core lugs which form side openings 14 and 15. In this way there are no out ends of strands at the distal end of the tube. core member withdrawn.
Conventional braiding machines lay pairs of strands spirally over two and under two crossing strands. This is objectionable for the present purpose because the stiffness of the strands causes them to bow outward and inward over and under the crossing strands to a braided thickness considerably in excess of double strand thickness. In order to minimize the wall thickness of the tube for maximum flexibility in bending, the braiding machine is modified to lay single strands over and under single cross-- ing strands. This results in a braided thickness for each layer of braiding exactly equal to twice the strand thickness. Then on the return course of braiding the outer layer strands fall into mesh with the under layer strands so that the two layers of braiding have a combined thickness less than four times the strand thickness.
When monofilarnent strands are used, the strands in one spiral direction are stressed in tension while the strands in the opposite spiral direction are stressed in compression, when the tube is twisted at its proximal end. Monofilament strands of wire, nylon or Teflon have strength in compression as well as tension when confined by being embedded in the wall of the plastic tube. Some advantage over an unreinforced plastic tube is gained by using strands of short fibers spun together as in a textile thread but in such case the strands have no strength in compression and only the tension strands are effective to improve the torsional stiffness. Because of their spiral directions the reinforcing strands, even when metal Wire is used, do not impair the flexibility of the tube in bending. A suitable X-ray opaque material is incorporated in the plastic composition of the tube to provide as much opacity as possible.
FIGURE 6 shows a modification having additional reinforcement up to the point 12a which corresponds to the point 12 in FIGURE 1 at the beginning of taper of the distal end. In this case before the two layers of braiding 21 and 22 are applied as above described, a preliminary braiding operation is performed to apply a first layer of braided strands 33 from the proximal end out to the point 12a and then reversing back to apply an overlying layer 34 which continues back to the proximal end of the tube. The extra reinforcement 33, 34 referably underlies the layers 21, 22 for exterior smoothness, and all four layers are completely embedded in the plastic so that all of the reinforcing strands are covered by the plastic material of the tube. The arrangement in FIGURE 6 provides still greater torsional rigidity throughout the main length of the catheter tube while leaving the tapered distal end portion slender to function as a pilot in guiding the tube through body channels. The four layers of braiding mesh together so that their combined thickness is substantially less than eight times the strand thickness.
When the catheter tube is twisted, the spiral strands in one direction, those under tension, tend to contract inwardly and the spiral strands in the opposite direction, those under compression, tend to expand outwardly. The braiding interlocks the tension and compression strands so that there is no contraction or expansion in the tube. Other strand configurations may be devised to neutralize the contraction and expansion tendencies of the tension and compression strands in order to achieve torsional rigidity. Also, the reinforcing strands may be incorporated in the wall of the plastic tube by other methods of manufacture.
In some cases it may be desired to terminate the strand reinforcement short of the tip in order to provide the greatest possible flexibility in bending at the tip. For this purpose the end portion of the tube may be made of a softer plastic material, the main length of the tube being relatively stiffer for pushing the tube a considerable distance through an artery or vein. The two different plastics may be molded integrally or they may be molded separately and then welded together end to end. The taper need not extend to the tip end. For the present purpose the tip end is made straight for three-fourths of an inch and the tapered portion extends back another threefourths of an inch and the tapered portion extends back another three fourths of an inch. Such details will vary according to the purpose of the catheter and the techniques employed in its use.
An insertable bending device is shown in FIGURES 7 to 13. This device comprises a flexible guide tube 40 for assuming the thrust reaction of a flexible Bowden pull wire 41. Tube 40 is preferably formed by winding a tight coil of spring wire with the adjacent turns in contacting relation so that the tube will not compress longitudinally but is freely flexible in bending. The distal end of guide tube 40 is seated in a bore 42 in a head block 43 as shown in FIGURE 8. The Bowden wire 41 slides freely through guide tube 40 and a guide bore 44 in the end of the block. The end of Bowden wire 41 is reversely bent to anchor it in a bore'45 in an end block 46. Surrounding the Bowden wire is a compression spring 47 having its ends abutting the two blocks to urge them away from each other.
The blocks 43 and 46 are interconnected by a flexible strut 50 at one side of the Bowden wire. This strut comprises a coil of spring wire similar to the guide tube 40.
The coil is incompressible in a longitudinal direction and its ends bear against the confronting faces of blocks 43 and 46 to maintain a predetermined spacing of the blocks at their under sides as viewed in FIGURE 8. The coil 50 is held in this position by a resilient center guide wire 51 which passes through bores 52 in the two blocks and has opposite end portions 53 bent over the opposite ends of the blocks. Thus, the coil performs the function of a flexible strut While the center wire 51 supports the strut in position between the blocks at one side of the Bowden wire. The bending element comprising blocks 43 and 46 and associated parts is designated in its entirety by numeral 55.
The Bowden wire 41 is tensioned by a manual actuating device 60 to bend the strut 50. One end of tensioning device 60 is equipped with a tapered male frictional connector fitting 61 which fits in the bore of female connector fitting 11 on the proximal end of the catheter tube in FIGURE 1. Thus, the bending element 55 and flexible guide tube 40 with its Bowden wire 41 may be inserted through the passageway 16 of the catheter tube until the bending element 55 reaches the desired position near the end of the catheter tube, as shown in FIGURE 9. The head block 43 and end block 46 are somewhat smaller than passageway 16 so that the passageway is not occluded by the bending element. Guide tube 40 is considerably smaller than passageway 16. A 90 bend is shown in FIGURE 9. The element 55 is capable of producing a 180 bend in the end of the catheter tube. The reinforcing strands 21, 22 are present in tube in FIG- URE 9 but are not shown. For the present purpose the bending element 55 is disposed in the cylindrical portion of tube 10 back of tapered portion 17 but for other purposes the bending element may be located as close to the tip of the tube as desired.
The body of actuating device 60 comprises a front tubular member 62 and a rear tubular member 63. These members contain a longitudinal bore 64 for the Bowden wire guide tube 40 as shown in FIGURE 10. The rear end of member 62 is flanged at 65 for swivel connection to the front end of member 63 by means of a threaded union-type coupling 66. An annular recess in the forward end of member 63 contains an O-ring seal 67. When coupling 66 is tightened, the swivel joint is locked and made liquid-tight.
The forward end of member 62 contains a side branch 68 having a passageway 69 in communication with the passageway 64. This side branch is equipped with a female connector fitting 11. Mounted on the forward end of member 62 is a swivel end member 70 which carries the previously mentioned male connector fitting 61. This swivel joint is the same as the swivel joint just described between members 62 and 63 except that in this case union coupling 66a may be left sufliciently loose to permit free rotation of the end member by means of its knurled collar 71. When end member 70 is thus rotated, the frictional connection between connector fittings 11 and 61 causes catheter tube 10 to rotate and with it the guide tube 40, Bowden wire 41 and bending element 55. Guide tube 40 and Bowden wire 41 are relativey long and very slender whereby they have negligible torsional stiffness to resist such rotation. End member 70 has a longitudinal passageway 64a communicating with passageway 64 for guide tube 40. O-ring 67 seals the swivel joint and provides sufficient friction to hold the catheter tube in adjusted rotative position.
The rear end of body member 63 contains a bore 74 at the end of passageway 64 to receive the inner end of catheter bending core 75. This core element has a cylindrical metal inner end 76 which fits the bore'74 and is sealed by O-ring 67. A flange 77 is retained against the end of member 63 by means of threaded and flanged union coupling 66b. As shown in'FIGURE 11, the cylindrical portion 76 has a bore 78 to receive and seat the proximal end of guide tube 40 and in continuation of this bore is a smaller bore 79 for the Bowden wire 41. A larger bore 80 contains a pair of rubber discs 81 which are slightly larger than the bore 80 whereby the discs assume a cupped shape, making a tight seal against the wall of the bore. Bowden wire 41 is pierced through these discs to form a liquid-tight seal between the wire and the discs while at the same time permitting longitudinal movement of the wire. The sealing discs 81 are retained by an annularly grooved metal plug 82 which is secured by a crimped rearwardly extending cylindrical wall portion 83 integral with cylindrical portion 76 and flange 77. The forward end of plug 82 and the inner end of bore 80 are conical to maintain the cupped shape of discs 81 whereby the discs form the equivalent of chevron-type sealing rings.
A metal bottom 85 has a recessed forward and enclosing plug 82 and an annular rim 86 adapted to seat against flange 77 Extending through the button is a longitudinal passageway 87 for the Bowden wire and the reduced outer end of the button is provided with a diametral slit 88 which intersects the outer end of passageway 87. The button also has an annular groove 89 for actuation by the palm lever 90 in FIGURE 10. In assembling the bending device, the bending element 55 is disposed in straight condition as shown in FIGURE 8 and the proximal end of the Bowden wire 41 is bent radially through slit 88, 360 around the small rear end of button 85 and then again diametrally through slit 88, and then the walls of the slot are pinched together to clamp and securely anchor the Bowden wire. Guide tube 40 is of a length that will place bending element 55 as close to the end of the catheter tube as desired.
Palm lever 90 has a forked end 91 engaging annular groove 89 to tension the Bowden Wire. Palm lever 90 is an L-shaped or bell crank lever which is pivotally mounted at its angle point on a pin 92 at the rear end of a supporting arm 93. A leaf spring 94 in the angle between the two arms urges the palm lever outward to hold button 85 normally seated against flange 77. The forward end of arm 93 is pivotally mounted at 95 on tubular member 63. This arm is equipped with a coil spring 96 urging the arm toward the member 63 and has a foot 97 to bear against member 63. A headed screw 98 extends through an open ing 99 adjacent the forked end of palm level 90 and is threaded through stop foot 97 to provide an adjustable stop for limiting the squeezing movement of palm lever 90 in pulling the Bowden wire rearward.
By lifting supporting arm 93 the forked end 91 of the palm lever is disengaged from button 85 and by unscrewing coupling 6617, the core element 75, guide tube 40 and bending element 55 may be withdrawn from the rear end of the handle body.
From the foregoing description it will be apparent that the manipulation of the catheter banding device involves two different movements which must be coordinated in order to guide the tip of the catheter into a branch artery or other lateral passageway or opening. These two movements comprise the bending action as shown in FIGURE 9 and the rotation of the bent end of the catheter tube to the proper direction. FIGURE 13 illustrates how the bending device provides for coordination of these two movements by a simple manipulation of one hand. Palm or squeezing pressure on lever 90 controls the degree of bending while the thumb and index finger rotate collar 71 to control the direction of bending.
The frictional engagement of bending element 55 with the inside of the catheter tube causes the bending element to rotate with the tube when collar 71 is rotated. Preferably, the rotative adjustment is performed first while there is but little palm pressure on lever 90. Then, when bending element 55 has been oriented in the proper direction to enter the desired ibranch artery, its bending angle may be increased by additional palm pressure on lever 90 as the catheter is pushed forward through the aorta. Also,
small changes in orientation of the bending element may be accomplished during any degree of bending by twisting the wrist to rotate the whole actuating device 60 as a unit. Stop screw 93 may be adjusted before insertion of the catheter into the artery, to allow the maximum desired bending angle so that excessive palm pressure during manipulation will not bend the catheter too much.
When the tip of the catheter has been inserted into the desired coronary artery or other branch passage, the entire bending device may be removed, if desired. However, the present bending device is specially constructed so that the usual functions of a catheter tube may be carried out without removing the bending device. This is the purpose of branch tube 68.
The exploded portion of FIGURE 13 shows a tree of three-way valves for connection with branch tube 68. These valves 110, 111 and 112 each have one male connector fitting 61 and two female connector fittings 11 whereby they may be connected together in series to provide branch circuits for various purposes. Each valve has an operating lever 113 which is rotatable to different positions. It is understood that the male connector 61 of valve 110 is inserted in female connector 11 of branch tube 68. Thus, the upright connector 11 on valve 110 may lead to a pressure measuring instrument, the upright connector 11 on valve 111 may lead to an elevated source of glucose solution, the upright connector on valve 112 may be connected with syringe 115 and the end connector '71 on valve 112 may lead to an elevated source of X-ray opaque fluid.
At any time while the catheter is [being used for monitoring pressure readings, the operator can selectively draw either glucose of X-ray opaque material into the syringe. Then by rearranging the valve positions, the material in the syringe may be ejected into the catheter under pressure. Following ejection of material through the catheter, the operator can return to pressure monitoring by re-positioning the first valve. These operations may all be performed while the bending element 55 is in the catheter tube or the bending element may be removed, as desired. It is therefore clear that the tube per se may be attached to a variety of instrumentalities.
The swivel joint between handle body members 62 and 63 permits the valve tree to be turned to a convenient position and then the joint may be clamped rigid by coupling 66.
Although the catheter has been described in connection with coronary artery diagnosis, it is to be understood that no limitation on its use is intended. The principles of the invention are applicable to catheters for all purposes.
As mentioned hereinabove, other strand configurations and other means may be employed to neutralize the contraction and expansion tendencies of the tension and compression strands and the reinforcing strands may be incorporated in the wall of the plastic tube by other methods of manufacture. Polyvinyl chloride, for example, has the advantage of a wide range of degrees of flexibility. It is available in a hard grade which is suitable to act as a binder spiral layers of wire whereby the braiding operation may be eliminated.
In such a process of manufacture, a very thin tube of plastic is first passed over the mandrel. A layer of multiple strands is then wound in one spiral direction and reversed back toward the starting end so as to cross the turns of the under layer of strands. Finally, a heavier tube of plastic is shrunk over the windings to embed the strands and then the assemblage is molded in a die as illustrated and described herein. This leaves all the strand ends at the proximal end of the tube with the turns in one layer being disposed in an opposite spiral direction to the turns of the other layer. The two layers of reinforcing strands are effectively interlocked by the plastic so that the coils of one layer cannot contract or expand relative to the coils of the other layer when the tube is twisted. In this way torsional rigidity is achieved without a braided interlock. It is, of course, understood that the hard plastic employed is not of such hardness as to impair the desired flexibility in bending but merely of sufiicient hardness to provide an effective interlock between the inner and couter courses of the reinforcing strands.
Having now described my invention and in what manner the same may be used, what I claim as new and desire to protect by Letters Patent is:
1. A manipulative catheter comprising a tube of flexible plastic material having a distal end adapted for insertion into a body passage of a patient and a proximal end adapted to remain outside said body passage, said tube being adapted to be pushed through said body passage, and torsional rigidifying means incorporated in said tube so that said distal end may be rotated to a predetermined orientation in said body passage by twisting said proximal end, said rigidifying means comprising strands of tension material disposed in the wall of said tube in opposite spiral directions so as to impart torsional rigidity without appreciably increasing the resistance of the tube to bending whereby the tube will freely follow curves in said body passage, said strands being disposed in two layers with all the strand ends being at said proximal end of the tube which remains outside the body passage, the underlying layer being doubled back upon itself at the distal end portion of the tube to form an overlying layer continuing from the underlying layer without any strand ends at said distal end of the tube.
2. A catheter as defined in claim 1, said strands in opposite directions being braided together.
3. A catheter as defined in claim 2, said strands in opposite directions each being braided over one and under one to minimize the thickness of the braided layer.
4. A catheter as defined in claim 1, said strands comprising a monofilament material having strength in compression as well as tension.
5. A catheter as defined in claim 1, including a second double layer of strands extending to a point more remote from said distal end than said first double layer and doubled back so that all its strand ends are at said proximal end of the tube, whereby the distal end portion of the tube is reinforced by a double layer of said strands and the rest of the length of the tube is reinforced by two double layers of said strands, said distal end portion of the tube tapering in thickness.
6. A catheter as defined in claim 1, said two layers of spiral strands comprising a continuous winding extending in a direction away from said proximal end of the tube and then back on itself to said proximal end.
7. In a catheter tube as defined in claim 1, means for bending the distal end of the tube, and means at the proximal end of the tube for actuating said bending means, said bending means being insertable in and removable from said tube.
8. A catheter as defined in claim 1 including a rotatable connection between said body member and said body member connector fitting whereby said catheter tube may be rotated relative to said body member.
9. A device for bending a catheter tube comprising a flexible guide tube having an opening in its distal end portion, a Bowden pull wire slidable in said guide tube, said wire having a distal end portion emergent from said opening in said guide tube, means forming a flexible strut extending beyond said opening and having an outer end connected with the distal extremity of said wire, said strut means having an opposite end adjacent said opening arranged to react against said guide tube when said wire is tensioned causing said strut means to bend, means on the other end of said guide tube for tensioning said wire to bend said strut, and a compression spring coiled around said emergent portion of said wire between said opening and said extremity connection to straighten said strut when said wire is relaxed.
10. A device for bending a catheter tube comprising a flexible guide tube, a head block on one end of said guide tube, a Bowden wire having free sliding movement through said guide tube and head block, an end block connected with one end of said Bowden wire in spaced relation in said head block, a flexible strut extending between said blocks at one side of said Bowden wire for maintaining said spaced relation of said blocks, means on the other end of said guide tube for tensioning said Bowden wire to bend said strut, and a compression spring coiled around said Bowden wire and abutting said blocks at its opposite ends to straighten said street when said Bowden wire is relaxed.
11. A device as defined in claim 10, said head block having a bore with an end wall to seat said one end of said guide tube, and a bore in said end block arranged to anchor said one end of said Bowden wire.
12. A device as defined in claim 10, said strut comprising a cylindrical coil of Wire abutting said blocks at its opposite ends, the turns of said wire being in contact with each other so that the coil is longitudinally incompressible, and a guide Wire within said coil anchored at its ends in said blocks.
13. A catheter comprising a molded tube of plastic material, a torsional rigidifying reinforcement molded in the wall of the tube comprising at least one pair of layers of spiral strands of monofilament material, and a device for bending the distal end of the tube comprising a flexible guide tube within said catheter tube, a head block on the distal end of said guide tube, a Bowden wire having free sliding movement through said guide tube and head block, an end block connected with the distal end of said Bowden wire in spaced relation to said head block, a flexible strut extending between said blocks at one side of said Bowden wire for maintaining said space relation of said blocks, means on the proximal end of said guide tube for tensioning said Bowden Wire to bend said strut whereby said catheter tube is bent, and a compression spring coiled around said Bowden wire and abutting said blocks at its opposite ends to straighten said strut when said Bowden wire is relaxed.
14. A catheter comprising a freely flexible and substantially limp tube having a connector fitting on its proximal end, a bending device for said tube comprising a body member having a connector fitting for connection with said tube fitting, a freely flexible and substantially limp guide tube projecting out of said body member fitting removably received in said catheter tube, a bending element on the distal end of said guide tube for bending the distal end of said catheter tube, and means on said body member operable through said guide tube for flexing said bending element.
15. A catheter as defined in claim 14 including a passageway in said body member containing a proximal end portion of said guide tube and communicating with said first tube, a branch tube connection on said body member communicating with said passageway, and means for closing said passageway on the proximal side of said branch tube connection.
16. A catheter as defined in claim 14 including means on said body member for rotating one of said tubes relative to said body member.
17. A catheter as defined in claim 16, said rotatable tube including reinforcement means to impart torsional rigidity to the tube.
18. A catheter handle and bending device comprising an elongated body having a longitudinal passageway therein, a connector fitting for a catheter tube on the distal end of said body in communication with said passageway, a flexible guide tube extending out of said passageway and fitting for insertion in and removal from the catheter tube, a bending element on the distal end of said guide tube for bending the distal end of said catheter tube, a pull wire in said guide tube for flexing said bending element, means in said body for seating the proximal end of said guide tube, an operating lever mounted on said body,
means for detachably connecting said lever with said pull wire, means on said body for rotating one of said tubes relative to said body, a branch tube connection on said body communicating with said passageway, and means on the proximal side of said branch tube connection for closing said passageway.
19. A device as defined in claim 18, said means for detachably connecting said lever with said pull wire comprising a slidable member extending from the proximal end of said body, and means on said member for anchoring the proximal end of said pull Wire, said lever engaging and moving said member to tension said pull wire.
20. A device as defined in claim 18, said elongated body comprising a proximal end member and a distal end member, said operating lever being on said proximal end member and said branch tube being on said distal end member, and means connecting said members together end to end with said operating lever and branch tube turned in different directions about the axis of said longitudinal passageway in adjustable relation.
21. A device for guiding a catheter into a branch tube at an angle from the direction of approach comprising an elongated handle body having a longitudinal passageway therein, a flexible guide tube extending out of said passageway for insertion in and removal from a catheter tube, said guide tube comprising a tight coil of Wire having adjacent turns in contacting relation, a bending element on the distal end of said guide tube, a pull wire slidable in said guide tube for flexing said bending element, means in said body for seating the proximal end of said guide tube, an operating lever mounted on said body for tensioning said pull wire, and means providing detachable connection between said pull wire and operating lever, said guide tube and pull wire being removable from said handle body.
22. A manipulative catheter apparatus comprising a catheter tube having a central passage, said catheter tube having in the walls thereof a plurality of spirally disposed courses of metal wire, said wires terminating at the proximal end thereof, said walls comprising flexible plastic material to prevent fluid passage therethrough, a flexible guide tube held lightly within said passage comprising a tightly wound helical coil of metal wire extending from the proximal end of said passage through a major portion of the length thereof, a cantilever spring attached to the distal end of said guide tube and eccentric thereto, said spring extending loosely through a minor length of said passage, a pull wire within said guide tube attached at its distal end to the distal end of said spring, a lever-equipped handle mechanism rotatably attached to the proximal end of the catheter tube, said guide tube abutting said handle mechanism, said pull wire being attached at its proximal end to the lever of said handle, the combination of which to provide a torsionally stable catheter whereby the bendable distal tip may be manipulated into difficult positions.
23. A manipulative catheter apparatus comprising a catheter tube having a central passage, said catheter tube having in the walls thereof a plurality of spirally disposed courses of metal wire, said wires terminating at the proximal end thereof, said walls comprising flexible plastic material to prevent fluid leakage therethrough, a flexible guide tube held lightly within the passage comprising a tightly wound helical coil of metal wire extending from the proximal end of said passage through a major portion of the length hereof, a helical compression spring of metal wire distal to said guide tube loosely held in said passage abutting and in axial alignment with said guide tube extending through a minor length of said passage, a cantilever spring attached to both ends of said compression spring, a pull wire within said guide tube and compression spring extending the full length of both, the distal end of said pull wire being attached to the distal end of said cantilever spring, a lever-equipped handle mechanism rotatably attached to the proximal end of the catheter tube, said guide tube abutting said handle mechanism, said pull wire being attached at its proximal end to the lever of said handle, the combination of which to provide a torsionally stable catheter whereby the bendable distal tip may be manipulated into difiicult positions.
24. A manipulative catheter for exploring blood vessels comprising: a tube of flexible material having a central passageway and having a distal end for insertion into a tortuous passage in the body of a patient, said distal end having radial openings from said passage through the tube wall and a proximal end adapted to remain outside said passage; means embedded in the wall of said tube resistant to torsional deflection of said tube about its longitudinal medial line; a connector secured to said proximal end and adapted to attach said proximal end to a variety of instrumentalities each adapted to operate through said central passage, said connector, when so attached being freely rotatable relative to said instrumentalities and when thus rotated acting to rotate both ends and all porions of said tube about said medial line, said reinforcing means being so designed that said tube is freely bendable transverse to said medial line.
25. A catheter handle for manipulating a catheter having a bending element in its tip, comprising an elongated body having a longitudinal bore therethrough, a catheter connector fitting swivel mounted on the forward end of said body in communication with said bore for rotating the catheter, an operating lever mounted on said body, a pull wire for flexing said bending element extending through said connector fitting and said bore and connected with said operating lever, a seal for said pull wire in said bore, a branch tube on said body com municating with said bore between said connector fitting and said seal, a thrust tube adapted for insertion in the catheter surrounding said pull wire and arranged to assume the thrust reaction of said pull wire on said bending element, and means in said bore to assume the thrust reaction of said tube.
References Cited UNITED STATES PATENTS 2,688,329 9/1954 Wallace 128-349 3,058,473 10/1962 Whitehead 128349 1,977,209 10/ 1934 Sargent 264103 2,810,424 10/ 1957 Swartswelter 264-103 1,011,090 12/1911 Subers 138130 2,788,804 4/1957 Larkin 138-125 2,961,675 11/1960 Stickney 15-104.38 3,010,357 11/1961 Hirschowitz 1286 X 3,093,160 6/1963 Boggs 138125 2,893,395 7/1959 Buck 128---349 FOREIGN PATENTS 156,901 11/1956 Sweden.
DALTON L. TRULUCK, Primary Examiner.
US. Cl. X.R. 138-123 UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION Patent No. 3,416,531 December 17 1968 Miles Lowell Edwards pears in the above identified It is certified that error ap cted as patent and that said Letters Patent are hereby corre shown below:
line 54, "banding" should re Column 7 line ad bending Column 6, 58 after "binders" insert between Column 8 line 54 the claim reference numeral "1'' should read l4 Column 9, line 10, "street" should read strut line 33, "space should read spaced Signed and sealed this 17th day of March 1970.
WILLIAM E. SCHUYLER, JR.
Edward M. Fletcher, J r.
Commissioner of Patents Attesting Officer
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1011090 *||Oct 17, 1910||Dec 5, 1911||Lawrence A Subers||Fire-hose and analogous tubing constructed of laminated cohesive interwound members having varying limits of elasticity.|
|US1977209 *||Dec 1, 1931||Oct 16, 1934||Macintosh Cable Company Ltd||Electric cable|
|US2688329 *||Mar 19, 1953||Sep 7, 1954||American Cystoscope Makers Inc||Catheter|
|US2788804 *||Mar 30, 1954||Apr 16, 1957||Fidelity Machine Company Inc||Flexible hose|
|US2810424 *||Mar 20, 1953||Oct 22, 1957||Aetna Standard Eng Co||Method and apparatus for making reinforced plastic tubing|
|US2893395 *||Feb 8, 1957||Jul 7, 1959||Becton Dickinson Co||Medical assembly and unit for liquid transfer|
|US2961675 *||Dec 5, 1958||Nov 29, 1960||Stickney Harold S||Conduit cleaning device|
|US3010357 *||Dec 28, 1956||Nov 28, 1961||Lawrence E Curtiss||Flexible light transmitting tube|
|US3058473 *||Nov 27, 1959||Oct 16, 1962||Whitchead Alfred E||Remotely directing catheters and tools|
|US3093160 *||Dec 4, 1959||Jun 11, 1963||H D Boggs Company Ltd||Plastic articles|
|SE156901A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3485234 *||Apr 13, 1966||Dec 23, 1969||Cordis Corp||Tubular products and method of making same|
|US3500820 *||Jul 1, 1966||Mar 17, 1970||Torsten Hakan Oskar Almen||Medical probe for injecting x-ray contrast medium into the body|
|US3503385 *||Sep 27, 1965||Mar 31, 1970||Cordis Corp||Guidable catheter assembly and manipulator therefor|
|US3509883 *||Nov 29, 1967||May 5, 1970||Gen Electric||Expanding cannula|
|US3521620 *||Oct 30, 1967||Jul 28, 1970||Cook William A||Vascular coil spring guide with bendable tip|
|US3552384 *||Jul 3, 1967||Jan 5, 1971||American Hospital Supply Corp||Controllable tip guide body and catheter|
|US3568660 *||Nov 20, 1967||Mar 9, 1971||Battelle Development Corp||Pacemaker catheter|
|US3598126 *||Jul 25, 1968||Aug 10, 1971||Baxter Laboratories Inc||Vascular canula for medical applications|
|US3599676 *||Jul 19, 1968||Aug 17, 1971||George Angus Canada Ltd||Firehose|
|US3618613 *||May 19, 1969||Nov 9, 1971||Heyer Schulte Corp||Antithrombotic intravascular catheter reinforced with nonkinking means|
|US3618614 *||May 6, 1969||Nov 9, 1971||Scient Tube Products Inc||Nontoxic radiopaque multiwall medical-surgical tubings|
|US3635223 *||Dec 2, 1969||Jan 18, 1972||Us Catheter & Instr Corp||Embolectomy catheter|
|US3829903 *||Mar 15, 1973||Aug 20, 1974||Dow Corning||Method of inhibiting blood clot on silicone rubber medical devices|
|US3897775 *||Aug 19, 1974||Aug 5, 1975||Olympus Optical Co||Endoscope with facile bending operation|
|US3903895 *||May 1, 1974||Sep 9, 1975||Sherwood Medical Ind Inc||Cardiovascular catheter|
|US3924632 *||Jun 17, 1974||Dec 9, 1975||William A Cook||Fiber glass reinforced catheter|
|US4159022 *||Apr 25, 1977||Jun 26, 1979||Pevsner Paul H||Catheter delivery system and method|
|US4329983 *||May 9, 1980||May 18, 1982||Fletcher Thomas S||Guide device for endotracheal tubes|
|US4516972 *||Aug 12, 1983||May 14, 1985||Advanced Cardiovascular Systems, Inc.||Guiding catheter and method of manufacture|
|US4529400 *||Mar 23, 1984||Jul 16, 1985||Scholten James R||Apparatus for naso and oroendotracheal intubation|
|US4534363 *||Apr 26, 1984||Aug 13, 1985||Cordis Corporation||Coating for angiographic guidewire|
|US4547193 *||Apr 5, 1984||Oct 15, 1985||Angiomedics Incorporated||Catheter having embedded multi-apertured film|
|US4573576 *||Oct 27, 1983||Mar 4, 1986||Krol Thomas C||Percutaneous gastrostomy kit|
|US4586923 *||Jun 25, 1984||May 6, 1986||Cordis Corporation||Curving tip catheter|
|US4634432 *||May 13, 1985||Jan 6, 1987||Nuri Kocak||Introducer sheath assembly|
|US4639252 *||Apr 5, 1985||Jan 27, 1987||Research Medical, Inc.||Venous return catheter|
|US4650466 *||Nov 1, 1985||Mar 17, 1987||Angiobrade Partners||Angioplasty device|
|US4650467 *||Aug 22, 1985||Mar 17, 1987||Sarcem S.A.||Remote control catheter|
|US4651753 *||Oct 12, 1984||Mar 24, 1987||Jayco Pharmaceuticals||Endoscopic multiple biopsy instrument|
|US4665604 *||Feb 16, 1982||May 19, 1987||Cordis Corporation||Non-fused torque control catheter|
|US4685457 *||Aug 29, 1986||Aug 11, 1987||Donenfeld Roger F||Endotracheal tube and method of intubation|
|US4690175 *||Dec 9, 1985||Sep 1, 1987||Kabushiki Kaisha Medos Kenkyusho||Flexible tube for endoscope|
|US4702252 *||Jan 27, 1986||Oct 27, 1987||Smiths Industries Public Limited Company||Catheters|
|US4787399 *||Jul 1, 1987||Nov 29, 1988||Sarcem S.A.||Remote controlled catheter guide|
|US4790331 *||Dec 2, 1986||Dec 13, 1988||Sherwood Medical Company||Method for placement of catheter in a blood vessel|
|US4799496 *||Jun 3, 1987||Jan 24, 1989||Lake Region Manufacturing Company, Inc.||Guide wire handle|
|US4817613 *||Jul 13, 1987||Apr 4, 1989||Devices For Vascular Intervention, Inc.||Guiding catheter|
|US4885003 *||Jul 25, 1988||Dec 5, 1989||Cordis Corporation||Double mesh balloon catheter device|
|US4899787 *||Jun 16, 1987||Feb 13, 1990||Kabushiki Kaisha Medos Kenkyusho||Flexible tube for endoscope|
|US4921484 *||Jul 25, 1988||May 1, 1990||Cordis Corporation||Mesh balloon catheter device|
|US4925445 *||Feb 9, 1989||May 15, 1990||Fuji Terumo Co., Ltd.||Guide wire for catheter|
|US4981478 *||Sep 6, 1988||Jan 1, 1991||Advanced Cardiovascular Systems||Composite vascular catheter|
|US5019057 *||Oct 23, 1989||May 28, 1991||Cordis Corporation||Catheter having reinforcing strands|
|US5037404 *||Nov 14, 1988||Aug 6, 1991||Cordis Corporation||Catheter having sections of variable torsion characteristics|
|US5057092 *||Apr 4, 1990||Oct 15, 1991||Webster Wilton W Jr||Braided catheter with low modulus warp|
|US5058577 *||May 9, 1989||Oct 22, 1991||Gary Six||Flexible tip stylet for use with an endotracheal intubation device|
|US5067957 *||Sep 27, 1988||Nov 26, 1991||Raychem Corporation||Method of inserting medical devices incorporating SIM alloy elements|
|US5069673 *||Feb 7, 1990||Dec 3, 1991||Cordis Corporation||Catheter with double step-down bore|
|US5095911 *||May 18, 1990||Mar 17, 1992||Cardiovascular Imaging Systems, Inc.||Guidewire with imaging capability|
|US5108411 *||Mar 28, 1990||Apr 28, 1992||Cardiovascular Imaging Systems, Inc.||Flexible catheter drive cable|
|US5125906 *||Nov 2, 1990||Jun 30, 1992||Arrow International Investment Corporation||Hand-held device for feeding a spring wire guide|
|US5147315 *||Apr 6, 1990||Sep 15, 1992||C. R. Bard, Inc.||Access catheter and system for use in the female reproductive system|
|US5176660 *||Mar 8, 1991||Jan 5, 1993||Cordis Corporation||Catheter having reinforcing strands|
|US5176661 *||Oct 15, 1991||Jan 5, 1993||Advanced Cardiovascular Systems, Inc.||Composite vascular catheter|
|US5190546 *||Apr 9, 1991||Mar 2, 1993||Raychem Corporation||Medical devices incorporating SIM alloy elements|
|US5217440 *||Oct 8, 1992||Jun 8, 1993||C. R. Bard, Inc.||Multilaminate coiled film catheter construction|
|US5231989 *||Feb 15, 1991||Aug 3, 1993||Raychem Corporation||Steerable cannula|
|US5254107 *||Sep 23, 1992||Oct 19, 1993||Cordis Corporation||Catheter having extended braid reinforced transitional tip|
|US5273042 *||Nov 5, 1991||Dec 28, 1993||Medical Parameters, Inc.||Guidewire advancement method|
|US5318032 *||Feb 5, 1992||Jun 7, 1994||Devices For Vascular Intervention||Guiding catheter having soft tip|
|US5327906 *||Apr 28, 1993||Jul 12, 1994||Medtronic, Inc.||Steerable stylet handle|
|US5334169 *||May 11, 1992||Aug 2, 1994||American Interventional Technologies, Inc.||Reinforced catheter with thin monolithic walls|
|US5345937 *||Jul 28, 1993||Sep 13, 1994||Raychem Corporation||Steerable cannula|
|US5358493 *||Feb 18, 1993||Oct 25, 1994||Scimed Life Systems, Inc.||Vascular access catheter and methods for manufacture thereof|
|US5396902 *||May 28, 1993||Mar 14, 1995||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5409015 *||May 11, 1993||Apr 25, 1995||Target Therapeutics, Inc.||Deformable tip super elastic guidewire|
|US5438993 *||Apr 26, 1994||Aug 8, 1995||Medical Parameters, Inc.||Guidewire advancement system|
|US5441489 *||Apr 11, 1990||Aug 15, 1995||Mitsubishi Cable Industries, Ltd.||Catheter with body temperature glass transition region|
|US5448993 *||Mar 31, 1994||Sep 12, 1995||Medical Parameters, Inc.||Guidewire advancement system|
|US5454795 *||Jun 27, 1994||Oct 3, 1995||Target Therapeutics, Inc.||Kink-free spiral-wound catheter|
|US5472435 *||May 21, 1993||Dec 5, 1995||Navarre Biomedical, Ltd.||Drainage catheter|
|US5478330 *||Mar 11, 1994||Dec 26, 1995||Cardiac Pathways Corporation||Steerable catheter with adjustable bend location and/or radius and method|
|US5484419 *||Jun 27, 1994||Jan 16, 1996||Arrow International Investment Corporation||Hand-held device for feeding a spring wire guide|
|US5490859 *||Apr 29, 1993||Feb 13, 1996||Scimed Life Systems, Inc.||Expandable intravascular occlusion material removal devices and methods of use|
|US5496294 *||Jul 8, 1994||Mar 5, 1996||Target Therapeutics, Inc.||Catheter with kink-resistant distal tip|
|US5501694 *||Mar 3, 1994||Mar 26, 1996||Scimed Life Systems, Inc.||Expandable intravascular occlusion material removal devices and methods of use|
|US5507728 *||Nov 22, 1994||Apr 16, 1996||Erskine; Timothy J.||Peristaltic interlumenar device advances|
|US5507995 *||Jul 12, 1994||Apr 16, 1996||Scimed Life Systems, Inc.||Process for making a catheter|
|US5524337 *||Sep 21, 1994||Jun 11, 1996||Ep Technologies, Inc.||Method of securing ring electrodes onto catheter|
|US5527307 *||Apr 1, 1994||Jun 18, 1996||Minimed Inc.||Implantable medication infusion pump with discharge side port|
|US5562619 *||Oct 19, 1993||Oct 8, 1996||Boston Scientific Corporation||Deflectable catheter|
|US5569218 *||Feb 14, 1994||Oct 29, 1996||Scimed Life Systems, Inc.||Elastic guide catheter transition element|
|US5597378 *||Oct 2, 1992||Jan 28, 1997||Raychem Corporation||Medical devices incorporating SIM alloy elements|
|US5599326 *||Dec 20, 1994||Feb 4, 1997||Target Therapeutics, Inc.||Catheter with multi-layer section|
|US5611777 *||Aug 23, 1995||Mar 18, 1997||C.R. Bard, Inc.||Steerable electrode catheter|
|US5614136 *||Mar 2, 1995||Mar 25, 1997||Scimed Life Systems, Inc.||Process to form dimensionally variable tubular members for use in catheter procedures|
|US5636642 *||Apr 25, 1995||Jun 10, 1997||Target Therapeutics, Inc.||Deformable tip super elastic guidewire|
|US5658264 *||Nov 10, 1994||Aug 19, 1997||Target Therapeutics, Inc.||High performance spiral-wound catheter|
|US5662119 *||Apr 21, 1995||Sep 2, 1997||Medtronic Inc.||Steerable stylet and manipulative handle assembly|
|US5662622 *||Apr 4, 1995||Sep 2, 1997||Cordis Corporation||Intravascular catheter|
|US5667499 *||Oct 4, 1994||Sep 16, 1997||Scimed Life Systems, Inc.||Guide catheter unibody|
|US5676659 *||Sep 26, 1995||Oct 14, 1997||Medtronic, Inc.||Small diameter, high torque catheter|
|US5682897 *||Sep 12, 1996||Nov 4, 1997||Cardiovascular Imaging Systems, Inc.||Guidewire with imaging capability|
|US5695483 *||Aug 17, 1995||Dec 9, 1997||Target Therapeutics Inc.||Kink-free spiral-wound catheter|
|US5702373 *||Aug 31, 1995||Dec 30, 1997||Target Therapeutics, Inc.||Composite super-elastic alloy braid reinforced catheter|
|US5711909 *||May 9, 1996||Jan 27, 1998||Cordis Corporation||Intravascular catheter and method of manufacturing|
|US5728063 *||Nov 24, 1995||Mar 17, 1998||Micro International Systems, Inc.||High torque balloon catheter|
|US5733400 *||May 8, 1996||Mar 31, 1998||Cordis Corporation||Intravascular catheter|
|US5749837 *||Aug 1, 1996||May 12, 1998||Target Therapeutics, Inc.||Enhanced lubricity guidewire|
|US5759173 *||Jul 3, 1996||Jun 2, 1998||Micro Interventional Systems||High torque balloon catheter|
|US5769796 *||Jan 22, 1997||Jun 23, 1998||Target Therapeutics, Inc.||Super-elastic composite guidewire|
|US5772609 *||Jun 28, 1996||Jun 30, 1998||Target Therapeutics, Inc.||Guidewire with variable flexibility due to polymeric coatings|
|US5782811 *||May 30, 1996||Jul 21, 1998||Target Therapeutics, Inc.||Kink-resistant braided catheter with distal side holes|
|US5791338 *||Jan 17, 1996||Aug 11, 1998||William T. Merchant||Endotracheal intubation apparatus|
|US5792157 *||Sep 30, 1996||Aug 11, 1998||Scimed Life Systems, Inc.||Expandable intravascular occlusion material removal devices and methods of use|
|US5795341 *||Jun 7, 1995||Aug 18, 1998||Target Therapeutics, Inc.||High performance spiral-wound catheter|
|US5810012 *||May 31, 1995||Sep 22, 1998||Medical Parameters, Inc.||Guidewire advancement system|
|US5827202 *||Mar 24, 1997||Oct 27, 1998||Baxter International Inc.||Guide wire dispenser apparatus and method|
|US5836868 *||Mar 25, 1996||Nov 17, 1998||Scimed Life Systems, Inc.||Expandable intravascular occlusion material removal devices and methods of use|
|US5843002 *||Jun 10, 1996||Dec 1, 1998||Baxter International Inc.||Guide wire dispenser apparatus and method|
|US5853400 *||Jun 3, 1997||Dec 29, 1998||Target Therapeutics, Inc.||High performance spiral-wound catheter|
|US5855552 *||Jun 13, 1997||Jan 5, 1999||Ep Technologies, Inc.||Catheter having ring electrodes secured thereon|
|US5863366 *||Nov 15, 1996||Jan 26, 1999||Heartport, Inc.||Method of manufacture of a cannula for a medical device|
|US5865800 *||Oct 8, 1996||Feb 2, 1999||Boston Scientific Corporation||Deflectable catheter|
|US5868718 *||Oct 24, 1996||Feb 9, 1999||Scimed Life Systems, Inc.||Process to form dimensionally variable tubular members for use in catheter procedures|
|US5873842 *||Jun 26, 1997||Feb 23, 1999||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5879499 *||Jun 17, 1996||Mar 9, 1999||Heartport, Inc.||Method of manufacture of a multi-lumen catheter|
|US5891112 *||Jun 7, 1995||Apr 6, 1999||Target Therapeutics, Inc.||High performance superelastic alloy braid reinforced catheter|
|US5891114 *||Sep 30, 1997||Apr 6, 1999||Target Therapeutics, Inc.||Soft-tip high performance braided catheter|
|US5897537 *||Aug 27, 1996||Apr 27, 1999||Scimed Life Systems, Inc.||Guide catheter having a plurality of filled distal grooves|
|US5897567 *||Sep 9, 1997||Apr 27, 1999||Scimed Life Systems, Inc.||Expandable intravascular occlusion material removal devices and methods of use|
|US5911715 *||Feb 13, 1997||Jun 15, 1999||Scimed Life Systems, Inc.||Guide catheter having selected flexural modulus segments|
|US5927345 *||Apr 30, 1996||Jul 27, 1999||Target Therapeutics, Inc.||Super-elastic alloy braid structure|
|US5935102 *||Oct 23, 1996||Aug 10, 1999||C. R. Bard||Steerable electrode catheter|
|US5938609 *||Aug 1, 1997||Aug 17, 1999||Cardiovascular Imaging Systems, Inc.||Guidewire with imaging capability|
|US5947940 *||Jun 23, 1997||Sep 7, 1999||Beisel; Robert F.||Catheter reinforced to prevent luminal collapse and tensile failure thereof|
|US5951539 *||Dec 19, 1997||Sep 14, 1999||Target Therpeutics, Inc.||Optimized high performance multiple coil spiral-wound vascular catheter|
|US5971975 *||Oct 9, 1996||Oct 26, 1999||Target Therapeutics, Inc.||Guide catheter with enhanced guidewire tracking|
|US6004310 *||Jun 17, 1998||Dec 21, 1999||Target Therapeutics, Inc.||Multilumen catheter shaft with reinforcement|
|US6011988 *||Apr 29, 1998||Jan 4, 2000||Arrow International Investment||Guidewire advancement system|
|US6036682 *||Dec 2, 1997||Mar 14, 2000||Scimed Life Systems, Inc.||Catheter having a plurality of integral radiopaque bands|
|US6063318 *||Jul 29, 1996||May 16, 2000||Ep Technologies, Inc.||Method of forming a catheter body from tubing segments|
|US6090099 *||May 24, 1996||Jul 18, 2000||Target Therapeutics, Inc.||Multi-layer distal catheter section|
|US6139510 *||May 11, 1994||Oct 31, 2000||Target Therapeutics Inc.||Super elastic alloy guidewire|
|US6143013 *||Apr 30, 1996||Nov 7, 2000||Target Therapeutics, Inc.||High performance braided catheter|
|US6152912 *||Jun 10, 1997||Nov 28, 2000||Target Therapeutics, Inc.||Optimized high performance spiral-wound vascular catheter|
|US6159187 *||Dec 6, 1996||Dec 12, 2000||Target Therapeutics, Inc.||Reinforced catheter with a formable distal tip|
|US6165163 *||Mar 26, 1999||Dec 26, 2000||Target Therapeutics, Inc.||Soft-tip performance braided catheter|
|US6165166 *||Jan 28, 1998||Dec 26, 2000||Schneider (Usa) Inc.||Trilayer, extruded medical tubing and medical devices incorporating such tubing|
|US6171296 *||Apr 28, 1998||Jan 9, 2001||Microtherapeutics, Inc.||Flow directed catheter|
|US6197014||Mar 11, 1998||Mar 6, 2001||Target Therapeutics, Inc.||Kink-resistant braided catheter with distal side holes|
|US6203507||Mar 3, 1999||Mar 20, 2001||Cordis Webster, Inc.||Deflectable catheter with ergonomic handle|
|US6212422||Jul 2, 1999||Apr 3, 2001||Scimed Life Systems, Inc.||Catheter having a high tensile strength braid wire constraint and method of manufacture|
|US6217566||Oct 2, 1997||Apr 17, 2001||Target Therapeutics, Inc.||Peripheral vascular delivery catheter|
|US6258080||Nov 18, 1998||Jul 10, 2001||Target Therapeutics, Inc.||Kink-free spiral-wound catheter|
|US6296631||Dec 12, 2000||Oct 2, 2001||Sean L. Chow||Flow directed catheter|
|US6306141||Jun 7, 1995||Oct 23, 2001||Medtronic, Inc.||Medical devices incorporating SIM alloy elements|
|US6322534||Oct 8, 1999||Nov 27, 2001||Cordis Corporation||Variable stiffness balloon catheter|
|US6368316||Jun 11, 1998||Apr 9, 2002||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US6464684||Sep 9, 1998||Oct 15, 2002||Scimed Life Systems, Inc.||Catheter having regions of differing braid densities and methods of manufacture therefor|
|US6477402||Sep 29, 1999||Nov 5, 2002||Arrow International Investment Corp.||Guidewire advancement system|
|US6482171||Jan 13, 1997||Nov 19, 2002||Heartport, Inc.||Multi-lumen catheter|
|US6500130||Dec 21, 2000||Dec 31, 2002||Scimed Life Systems, Inc.||Steerable guidewire|
|US6500285||Aug 23, 1999||Dec 31, 2002||Scimed Life Systems, Inc.||Method of making a catheter having interlocking ribbed bond regions|
|US6505066||Feb 1, 2001||Jan 7, 2003||Scimed Life Systems, Inc.||Catheter having a high tensile strength braid wire constraint and method of manufacture|
|US6508805 *||Oct 10, 2000||Jan 21, 2003||Scimed Life Systems, Inc.||Intravascular catheter with composite reinforcement|
|US6533770||Jan 21, 1998||Mar 18, 2003||Heartport, Inc.||Cannula and method of manufacture and use|
|US6551281||Jan 13, 2000||Apr 22, 2003||Medical Components, Inc.||Guide wire advancer and assembly and method for advancing a guide wire|
|US6629952||Dec 29, 2000||Oct 7, 2003||Scimed Life Systems, Inc.||High pressure vascular balloon catheter|
|US6648854||May 14, 1999||Nov 18, 2003||Scimed Life Systems, Inc.||Single lumen balloon-tipped micro catheter with reinforced shaft|
|US6689120||Aug 4, 2000||Feb 10, 2004||Boston Scientific Scimed, Inc.||Reduced profile delivery system|
|US6824553||Aug 25, 2000||Nov 30, 2004||Target Therapeutics, Inc.||High performance braided catheter|
|US6858024||May 18, 1999||Feb 22, 2005||Scimed Life Systems, Inc.||Guide catheter having selected flexural modulus segments|
|US6945970||Dec 27, 2001||Sep 20, 2005||Scimed Life Systems, Inc.||Catheter incorporating a curable polymer layer to control flexibility and method of manufacture|
|US6951555||Nov 7, 2000||Oct 4, 2005||Chase Medical, L.P.||Catheter having integral expandable/collapsible lumen|
|US7104979||Feb 19, 2002||Sep 12, 2006||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US7297302||Dec 4, 2002||Nov 20, 2007||Boston Scientific Scimed, Inc.||Catheter having a high tensile strength braid wire constraint and method of manufacture|
|US7306585||Sep 30, 2004||Dec 11, 2007||Engineering Resources Group, Inc.||Guide catheter|
|US7354430||Aug 25, 2005||Apr 8, 2008||Boston Scientific Scimed, Inc.||Catheter incorporating a curable polymer layer to control flexibility|
|US7597830||Jul 9, 2003||Oct 6, 2009||Boston Scientific Scimed, Inc.||Method of forming catheter distal tip|
|US7615043||Jun 23, 2004||Nov 10, 2009||Boston Scientific Scimed, Inc.||Medical device incorporating a polymer blend|
|US7674411||Apr 1, 2004||Mar 9, 2010||Boston Scientific Scimed, Inc.||Guide catheter having selected flexural modulus segments|
|US7674421||Dec 11, 2007||Mar 9, 2010||Engineering Resources Group, Inc.||Method of making a guide catheter|
|US7704245||Apr 13, 2004||Apr 27, 2010||Cook Incorporated||Large diameter delivery catheter/sheath|
|US7713215||Jan 31, 2008||May 11, 2010||Shriver Edgar L||Steering, piercing, anchoring, distending extravascular guidewire|
|US7763063||Jul 2, 2004||Jul 27, 2010||Bolton Medical, Inc.||Self-aligning stent graft delivery system, kit, and method|
|US7815599||Dec 10, 2004||Oct 19, 2010||Boston Scientific Scimed, Inc.||Catheter having an ultra soft tip and methods for making the same|
|US7824392||Aug 20, 2003||Nov 2, 2010||Boston Scientific Scimed, Inc.||Catheter with thin-walled braid|
|US7828790||Dec 3, 2004||Nov 9, 2010||Boston Scientific Scimed, Inc.||Selectively flexible catheter and method of use|
|US7841994||Nov 2, 2007||Nov 30, 2010||Boston Scientific Scimed, Inc.||Medical device for crossing an occlusion in a vessel|
|US7881809||Dec 5, 2006||Feb 1, 2011||St. Jude Medical, Atrial Fibrillation Division, Inc.||Electrophysiology/ablation catheter and remote actuator therefor|
|US7883474||Apr 30, 1996||Feb 8, 2011||Target Therapeutics, Inc.||Composite braided guidewire|
|US7909812||Sep 6, 2006||Mar 22, 2011||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US7918806||Feb 13, 2006||Apr 5, 2011||Boston Scientific Scimed, Inc.||Guide wire with adjustable flexibility|
|US7949412||Jun 1, 2006||May 24, 2011||Advanced Bionics, Llc||Coated electrode array having uncoated electrode contacts|
|US7955298 *||May 9, 2005||Jun 7, 2011||Medtronic Cryocath Lp||Defined deflection structure|
|US7955313||Dec 17, 2003||Jun 7, 2011||Boston Scientific Scimed, Inc.||Composite catheter braid|
|US7968038||Mar 8, 2010||Jun 28, 2011||Cook Medical Technologies Llc||Large diameter delivery catheter/sheath|
|US7972465||Feb 2, 2010||Jul 5, 2011||C. R. Bard, Inc.||Reinforced multi-lumen catheter|
|US8000764||Mar 29, 2007||Aug 16, 2011||St. Jude Medical, Atrial Fibrillation Division, Inc.||Electrophysiology/ablation catheter having second passage|
|US8007605||Jan 30, 2007||Aug 30, 2011||Bolton Medical, Inc.||Method of forming a non-circular stent|
|US8062345||Jul 26, 2007||Nov 22, 2011||Bolton Medical, Inc.||Delivery systems for delivering and deploying stent grafts|
|US8062349||Jan 31, 2007||Nov 22, 2011||Bolton Medical, Inc.||Method for aligning a stent graft delivery system|
|US8064978||Nov 24, 2004||Nov 22, 2011||Cathrx Ltd||Modular catheter|
|US8070790||Feb 13, 2006||Dec 6, 2011||Bolton Medical, Inc.||Capture device for stent graft delivery|
|US8190271||Aug 29, 2008||May 29, 2012||Advanced Bionics, Llc||Minimizing trauma during and after insertion of a cochlear lead|
|US8251976||Oct 27, 2009||Aug 28, 2012||Boston Scientific Scimed, Inc.||Medical device incorporating a polymer blend|
|US8260394||Oct 5, 2011||Sep 4, 2012||Cathrx Ltd||Modular catheter|
|US8271101||Jul 31, 2009||Sep 18, 2012||Advanced Bionics||Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead|
|US8292943||Feb 23, 2004||Oct 23, 2012||Bolton Medical, Inc.||Stent graft with longitudinal support member|
|US8308790||Feb 6, 2006||Nov 13, 2012||Bolton Medical, Inc.||Two-part expanding stent graft delivery system|
|US8317772||Mar 10, 2011||Nov 27, 2012||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US8328791||Nov 4, 2010||Dec 11, 2012||Stryker Corporation||Selectively flexible catheter and method of use|
|US8377035||Jan 17, 2003||Feb 19, 2013||Boston Scientific Scimed, Inc.||Unbalanced reinforcement members for medical device|
|US8382826||Aug 12, 2010||Feb 26, 2013||Edwards Lifesciences Corporation||Method of delivering a prosthetic heart valve|
|US8430988||Apr 15, 2011||Apr 30, 2013||C. R. Bard, Inc.||Reinforced multi-lumen catheter|
|US8449595||Nov 14, 2011||May 28, 2013||Bolton Medical, Inc.||Delivery systems for delivering and deploying stent grafts|
|US8500792||Mar 31, 2009||Aug 6, 2013||Bolton Medical, Inc.||Dual capture device for stent graft delivery system and method for capturing a stent graft|
|US8636788||Aug 3, 2012||Jan 28, 2014||Bolton Medical, Inc.||Methods of implanting a prosthesis|
|US8715705||Jul 29, 2009||May 6, 2014||Covidien Lp||Multilayer medical devices having an encapsulated edge and methods thereof|
|US8740963||Jun 8, 2006||Jun 3, 2014||Bolton Medical, Inc.||Methods of implanting a prosthesis and treating an aneurysm|
|US8795255||Nov 12, 2012||Aug 5, 2014||Boston Scientific Scimed, Inc.||Catheter with composite stiffener|
|US8968383||Sep 27, 2013||Mar 3, 2015||Covidien Lp||Delivery of medical devices|
|US8973239||Oct 18, 2010||Mar 10, 2015||Boston Scientific Scimed, Inc.||Catheter having an ultra soft tip and methods for making the same|
|US8998970||Mar 14, 2013||Apr 7, 2015||Bolton Medical, Inc.||Vascular prosthetic delivery device and method of use|
|US9017246||Nov 17, 2011||Apr 28, 2015||Boston Scientific Scimed, Inc.||Biliary catheter systems including stabilizing members|
|US9101506||Mar 12, 2010||Aug 11, 2015||Bolton Medical, Inc.||System and method for deploying an endoluminal prosthesis at a surgical site|
|US9173755||Dec 5, 2011||Nov 3, 2015||Bolton Medical, Inc.||Vascular repair devices|
|US9198786||Feb 1, 2007||Dec 1, 2015||Bolton Medical, Inc.||Lumen repair device with capture structure|
|US9220617||Jun 10, 2014||Dec 29, 2015||Bolton Medical, Inc.||Dual capture device for stent graft delivery system and method for capturing a stent graft|
|US9320631||Jan 31, 2007||Apr 26, 2016||Bolton Medical, Inc.||Aligning device for stent graft delivery system|
|US9333104||May 22, 2013||May 10, 2016||Bolton Medical, Inc.||Delivery systems for delivering and deploying stent grafts|
|US9364314||Jun 30, 2009||Jun 14, 2016||Bolton Medical, Inc.||Abdominal aortic aneurysms: systems and methods of use|
|US9408734||Dec 13, 2013||Aug 9, 2016||Bolton Medical, Inc.||Methods of implanting a prosthesis|
|US9408735||Jan 16, 2014||Aug 9, 2016||Bolton Medical, Inc.||Methods of implanting a prosthesis and treating an aneurysm|
|US9439751||Mar 15, 2013||Sep 13, 2016||Bolton Medical, Inc.||Hemostasis valve and delivery systems|
|US9554929||Mar 5, 2015||Jan 31, 2017||Bolton Medical, Inc.||Vascular prosthetic delivery device and method of use|
|US9561124||Jul 20, 2010||Feb 7, 2017||Bolton Medical, Inc.||Methods of self-aligning stent grafts|
|US9655712||Feb 10, 2016||May 23, 2017||Bolton Medical, Inc.||Vascular repair devices|
|US9775733||Mar 2, 2015||Oct 3, 2017||Covidien Lp||Delivery of medical devices|
|US9782186||Mar 2, 2015||Oct 10, 2017||Covidien Lp||Vascular intervention system|
|US9795765||Apr 11, 2011||Oct 24, 2017||St. Jude Medical International Holding S.À R.L.||Variable stiffness steering mechanism for catheters|
|US20010003795 *||Jan 12, 2001||Jun 14, 2001||Mitta Suresh||Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart|
|US20020123738 *||Feb 19, 2002||Sep 5, 2002||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US20030083623 *||Dec 4, 2002||May 1, 2003||Scimed Life Systems, Inc||Catheter having a high tensile strength braid wire constraint and method of manufacture|
|US20030109778 *||Sep 30, 2002||Jun 12, 2003||Cardiac Assist Devices, Inc.||Electrophysiology/ablation catheter and remote actuator therefor|
|US20030153937 *||Feb 6, 2003||Aug 14, 2003||Al-Qahtani Ali Saeed Mohammed||Apparatus for use in the treatment of choanal atresia|
|US20040049170 *||Jul 31, 2001||Mar 11, 2004||Snell Robert Adam||Balloon-free urinary catheter|
|US20040073158 *||Oct 9, 2003||Apr 15, 2004||Medtronic, Inc.||Guide catheter|
|US20040172049 *||Jun 7, 2002||Sep 2, 2004||Hoon-Bum Lee||Vascular anastomosis device|
|US20040181244 *||May 31, 2002||Sep 16, 2004||Hoon-Bum Lee||Vascular anastomosis device|
|US20040186489 *||May 31, 2002||Sep 23, 2004||Lee Hoon Bum||Anastomosis device|
|US20050010194 *||Jul 9, 2003||Jan 13, 2005||Scimed Life Systems, Inc.||Method of forming catheter distal tip|
|US20050033311 *||Jun 18, 2004||Feb 10, 2005||Guldfeldt Signe Uhre||Medical device comprising a braided portion|
|US20050049575 *||Jun 18, 2004||Mar 3, 2005||Robert Snell||Medical device|
|US20050049576 *||Jun 18, 2004||Mar 3, 2005||Robert Snell||Medical device|
|US20050049577 *||Jun 18, 2004||Mar 3, 2005||Robert Snell||Medical device|
|US20050149176 *||Dec 29, 2003||Jul 7, 2005||Scimed Life Systems, Inc.||Selectively light curable support members for medical devices|
|US20050209557 *||May 9, 2005||Sep 22, 2005||Cryocath Technologies Inc.||Defined deflection structure|
|US20050283135 *||Aug 25, 2005||Dec 22, 2005||Scimed Life Systems, Inc.||Catheter incorporating a curable polymer layer to control flexibility and method of manufacture|
|US20060074401 *||Sep 30, 2004||Apr 6, 2006||Ross Christopher D||Guide catheter|
|US20060265037 *||Nov 6, 2002||Nov 23, 2006||Kuzma Janusz A||Construction of cylindrical multicontact electrode lead for neural stimulation and method of making same|
|US20070005003 *||Dec 29, 2004||Jan 4, 2007||Patterson Ryan C||Reinforced multi-lumen catheter|
|US20070049903 *||Sep 6, 2006||Mar 1, 2007||Target Therapeutics, Inc.||Catheter with composite stiffener|
|US20070078455 *||Dec 5, 2006||Apr 5, 2007||Rassoll Rashidi||Electrophysiology/ablation catheter and remote actuator therefor|
|US20070208300 *||Mar 1, 2007||Sep 6, 2007||Applied Medical Resources Corporation||Gas insufflation and suction/irrigation tubing|
|US20070244537 *||Mar 29, 2007||Oct 18, 2007||Rassoll Rashidi||Electrophysiology/ablation catheter having second passage|
|US20080045921 *||Nov 24, 2004||Feb 21, 2008||Anderson Neil L||Modular Catheter|
|US20080091259 *||Dec 12, 2007||Apr 17, 2008||Boston Scientific Scimed, Inc.||Selectively Light Curable Support Members for Medical Devices|
|US20080125752 *||Aug 9, 2006||May 29, 2008||Boston Scientific Scimed, Inc.||Catheter assembly having a modified reinforcement layer|
|US20080228175 *||Mar 13, 2008||Sep 18, 2008||Ranier Limited||Medical device|
|US20090005758 *||Feb 27, 2008||Jan 1, 2009||Sonar Shah||Guide catheter|
|US20090048656 *||Nov 7, 2006||Feb 19, 2009||Ning Wen||Delivery Device for Delivering a Self-Expanding Stent|
|US20090062896 *||Aug 29, 2008||Mar 5, 2009||Overstreet Edward H||Minimizing Trauma During and After Insertion of a Cochlear Lead|
|US20090198153 *||Jan 31, 2008||Aug 6, 2009||Shriver Edgar L||Steering, piercing, anchoring, distending extravascular guidewire|
|US20090292237 *||Jul 31, 2009||Nov 26, 2009||Advanced Bionics, Llc||Modular Drug Delivery System for Minimizing Trauma During and After Insertion of a Cochlear Lead|
|US20100132879 *||Feb 2, 2010||Jun 3, 2010||C.R. Bard, Inc.||Reinforced multi-lumen catheter|
|US20110027334 *||Jul 29, 2009||Feb 3, 2011||Nellcor Puritan Bennett Llc||Multilayer medical devices having an encapsulated edge and methods thereof|
|US20110054596 *||Aug 12, 2010||Mar 3, 2011||Edwards Lifesciences Corporation||Method of Delivering a Prosthetic Heart Valve|
|US20110144625 *||Feb 7, 2011||Jun 16, 2011||Target Therapeutics, Inc.||Composite Braided Guidewire|
|US20110172643 *||Mar 10, 2011||Jul 14, 2011||Target Therapeutics, Inc.||Catheter with Composite Stiffener|
|US20110192008 *||Apr 15, 2011||Aug 11, 2011||C. R. Bard, Inc.||Reinforced multi-lumen catheter|
|US20140276644 *||Mar 14, 2014||Sep 18, 2014||Hlt, Inc.||Elastic Catheter|
|USRE31272 *||Dec 31, 1979||Jun 14, 1983||Catheter delivery system and method|
|USRE32306 *||Jun 7, 1985||Dec 16, 1986||Biosearch Medical Products, Inc.||Intubating device|
|USRE35595 *||Oct 21, 1993||Aug 26, 1997||Six; Gary||Flexible tip stylet for use with an endotracheal intubation device|
|CN103143104A *||Mar 4, 2013||Jun 12, 2013||宁波华科润生物科技有限公司||Bone filler conveying cannula with adjustable bending angle|
|CN103143104B *||Mar 4, 2013||Jul 1, 2015||宁波华科润生物科技有限公司||Bone filler conveying cannula with adjustable bending angle|
|DE3802976C1 *||Feb 2, 1988||Aug 10, 1989||Sterimed Gesellschaft Fuer Medizinischen Bedarf Mbh, 6600 Saarbruecken, De||Guide wire for catheters|
|DE3819372C1 *||Jun 7, 1988||Jan 4, 1990||Andreas Dr. 7800 Freiburg De Zeiher||Guide catheter|
|EP0029185A1 *||Nov 6, 1980||May 27, 1981||Siemens Aktiengesellschaft||Plastic tube|
|EP0715863A2||Nov 10, 1995||Jun 12, 1996||Target Therapeutics, Inc.||Catheter|
|EP0971755A1 *||Jan 19, 1999||Jan 19, 2000||Heartport, Inc.||Cannula and method of manufacture and use|
|EP0971755A4 *||Jan 19, 1999||Oct 10, 2001||Heartport Inc||Cannula and method of manufacture and use|
|EP0998955A1||Nov 5, 1999||May 10, 2000||Cordis Corporation||Variable stiffness balloon catheter|
|EP1686909A1 *||Nov 24, 2004||Aug 9, 2006||Cathrx Ltd||A modular catheter|
|EP1686909A4 *||Nov 24, 2004||Dec 1, 2010||Cathrx Ltd||A modular catheter|
|EP2599458A1 *||Nov 24, 2004||Jun 5, 2013||Cathrx Ltd||A modular catheter|
|WO1990014123A1 *||May 22, 1990||Nov 29, 1990||Target Therapeutics, Inc.||Catheter with low-friction distal segment|
|WO1991017782A1 *||May 17, 1991||Nov 28, 1991||Target Therapeutics||Catheter with low-friction distal segment|
|WO1993023105A1 *||May 10, 1993||Nov 25, 1993||American Interventional Technologies, Inc.||Reinforced catheter and method of manufacturing|
|WO1996015824A1||Nov 21, 1995||May 30, 1996||Micro Interventional Systems, Inc.||High torque balloon catheter|
|WO1998015311A1||Oct 7, 1997||Apr 16, 1998||Target Therapeutics, Inc.||Guide catheter with enhanced guidewire tracking|
|WO1998024502A1||Dec 8, 1997||Jun 11, 1998||Target Therapeutics, Inc.||Reinforced catheter with a formable distal tip|
|WO1998050098A1 *||May 8, 1998||Nov 12, 1998||Microvena Corporation||Improved multi-durometer catheter|
|WO1998056448A1||Jun 9, 1998||Dec 17, 1998||Target Therapeutics, Inc.||Optimized high performance multiple coil spiral-wound vascular catheter|
|WO1998058696A1||Jun 22, 1998||Dec 30, 1998||Beisel Robert F||Catheter reinforced to prevent luminal collapse and tensile failure|
|WO1999000072A1 *||Jun 23, 1998||Jan 7, 1999||Bernard Jean Noel||Apparatus for setting and removing parts such as endoprostheses|
|WO1999016494A1||Sep 29, 1998||Apr 8, 1999||Boston Scientific Limited (Incorporated In Ireland)||Soft-tip high performance braided catheter|
|WO1999017826A1||Oct 1, 1998||Apr 15, 1999||Boston Scientific Limited||Peripheral vascular delivery catheter|
|WO1999055407A1 *||Apr 28, 1999||Nov 4, 1999||Micro Therapeutics, Inc.||Flow directed catheter|
|WO2002096299A1||May 31, 2002||Dec 5, 2002||Hb Medicals Corporation||Anastomosis device|
|U.S. Classification||604/95.4, 600/585, 138/123, 600/433, 604/526|
|International Classification||A61M25/00, A61M25/01|
|Cooperative Classification||A61M25/09041, A61M25/0012, A61M2025/09175, A61M25/09, A61M25/0108|
|European Classification||A61M25/01C1, A61M25/09, A61M25/09C|