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Publication numberUS3428042 A
Publication typeGrant
Publication dateFeb 18, 1969
Filing dateAug 10, 1964
Priority dateAug 10, 1964
Publication numberUS 3428042 A, US 3428042A, US-A-3428042, US3428042 A, US3428042A
InventorsChesnut Merrill Gaines
Original AssigneeUnited Aircraft Corp
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Heart pump actuator
US 3428042 A
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Description  (OCR text may contain errors)

Feb. i8, i969 M. G. CHESNUT HEART PUMP AcTUAToR sheet Z @f2 Filed Aug. lO, 1964 United States Patent O 3,428,042 HEART PUMP ACTUATOR Merrill Gaines Chesnut, Arvada, Colo., assignor, by mesne assignments, to United Aircraft Corporation, a corporation of Delaware Filed Aug. 10, 1964, Ser. No. 388,526 U.S. Cl. 128-1 10 Claims Int. Cl. A61m 5/20; A61h 31/00; Fil-lb 9/10 ABSTRACT F THE DISCLOSURE A catheter for insertion into a patients circulatory system communicates blood from one chamber of a bellows pump, the other chamber of the pump driving the pump piston in response to fluid pressure communicated thereto from a positive displacement actuator pump which includes a pump (pressure) coil and a withdrawal (suction) coil mounted in one of two chambers, in magnetic communication with an armature reciprocally mounted in the other of said chambers. The armature has a stroke rate responsive to the magnitude of current in the coils, and is provided with a hollow recess so as to reduce its mass and, therefore, the delay time of the actuator pump. The other chamber has a pump piston reciprocally disposed therein which is rigidly connected to the armature, the piston also having a recess or cavity so as to reduce its inertia. Grooves provided in the housing of the pump adjacent the coils control the flux path between the coils and the armature so as to provide linear operation.

BACKGROUND OF THE INVENTION Field of invention This invention relates generally to a device for assisting the natural action of a defective heart. More particularly, it concerns an apparatus for assisting insufficient natural heart action by synthesizing the parameters of the patients physical heart Wave form.

The present invention relates to an improvement in the actuating mechanism shown in the copending application of Chesnut and Ball, Ser. No. 347,500, filed Feb. 26, 1964. This copending application relates to a heart-assisting system in which an open ended cannula is inserted into the descending aorta and expanded and contracted in timed relation to the patients natural heart beat as derived from one of the patients physiological parameters, such as the EKG wave form.

Description 0f the prior art Heart pumps fall into two general categories; those which augment the natural heart action by operating in series with the natural heart, and those which either partially or totally bypass the heart. The present system, and that disclosed in Ser. No. 347,500, are of the augmentation type and in counter distinction to the bypass type system operate in series with the heart while the heart is actually beat-ing and supplying blood to the arterial tree. The series or augmentation type systems reduce the work load of the heart by lowering the pressure head against which the ventricle must eject its contained blood, and aid the coronary circulation by increasing the blood flow during the correct phase of the natural heart cycle. This phase corresponds to the period of time when the resistance in the coronary circulation is at a minimum and has been found to be in, what is described as, a post systolic period. Consequently, in the augmentation system the flow and pressure developments are very accurately phased in timed relationships to the normal beating ac- 3,428,042 Patented Feb. 18, 1969 tion of the heart, in counter distinction to the parallel or bypass systems which have been used in the past for by-passing blood from the veins to the arteries when the heart may be arrested.

In the augmentation or series system described in Ser. No. 347,500, a reciprocating piston pump, phased with the patients EKG wave form, delivers fluid to and withdraws fluid from the patients aorta to achieve a controlled pressure wave form in the patients circulatory system. To achieve complete control over the patients synthesized pressure wave form, it was found desirable to control the length of stroke, the speed of stroke, and the delay time of the reciprocating piston artificial heart pump. The present invention relates to an actuator for driving the reciprocating piston heart pump particularly designed for operating room use and combining the advantages of fast response time, accuracy, and simplicity of construction.

As utilized in the operating room, the augmentation type system consists of three basic physical components, the reciprocating pump, an actuator for the pump, and a control console for directing predetermined commands to the actuator for controlling the mot-ion of the pump. As the catheters which supply and withdraw fluid from the aorta are most advantageously inserted into the patients femoral arteries, the pump itself is usually placed between the patients legs on the operating table during surgery or treatment. It has been found that when a hydraulic actuator is used, a plurality of hydraulic and electric control lines must run from the control component, which may house the source of hydraulic fluid, and the actuator located on the operating table, and this may, in some instances, result in there being too much apparatus and too -many hydraulic lines around the operating table thereby interfering with the surgeons and technicians7 work which during the operation must be directed wholly to the' patient rather than the equipment and apparatus.

Summary of invention It is, therefore, a primary object of the present invenciprocating pump heart augmentation system.

It is another object of the present invention to provide a new and simplified electric actuator for a reciprocating pump heart augmentation system permitting the reciprocating pump to be physically separated from the actuator and its associated circuitry so that only the reciprocating pump need be in the immediate vicinity of the operating table.

Another object of the present invention is to provide an electric actuator for driving a reciprocating heart pump in an augmentation type heart pump system which accurately controls all the pumping parameters.

A further object Iof the present invention is to provide an electric actuator for use in :an augmentation heart pump system wherein the control circuit is responsive to the patients physiological parameters.

According to the present invention ythere is provided a push-pull type -reciprocating electric actuator pump and a fluid coupling for a reciprocating heart pump. By utilizling :a fluid coupling, fthe electric actuator pump may be placed tothe side ofthe operating room and a single uid line may be connected between the .actuator and the reciprocating piston pump thereby providing a simplified pumping apparatus with an extremely fast response time due to fthe utilization of hydraulic fluid having a high bulk modulus.

Other objects and advantages will become readily apparent from the following detailed `description taken in connection with the accompanying drawings.

Brief description of the drawings FIG. l lis a schem-atic diagram of the complete heart augmentation system;

FIG. 2 is a cross sectional elevation of the heart pump and the electric -actuator connected by a fluid coupling; and

FIG. 3 is an electric circuit diagram showing a portion of the power switching amplifier in FIG. 1.

Description of the preferred embodiment While an illustrative embodiment of the invention is shown in the drawings land will be described in detail herein, the invention is susceptible of embodiment in many different forms and it should be understood that the present disclosure to be considered as an exemplification of the principles ofthe invention and is not intended to limit the invention to the embodiment illustrated. The scope of the invention will be pointed out in the appended claims.

Referring to FIG. 1 wherein the over-all augmentation system is shown in block diagram form, a myocardial augmentation instrumentation system (hereinafter referred to as MAIS) control, generally designated by numeral 10, receives an input signal from a suitable source, such as an electrocardiogram, which monitors one of the patients physiological parameters. The MAIS control shapes the input pulse, filters unwanted signals therefrom, and delays the input pulse behind a selected portion of the physiological input signal so that the pump cycle may be delayed therefrom in accordance with the surgeons desired augmentation technique. An output pulse from the MAIS control energizes the pump control circuit 11 wherein sui-table adjustments may be made by the surgeon to vary the length of pumping stroke and the speed of pumping on both pump and withdrawal strokes. The specific circuitry of the MAIS control 10 and the pump control 11 are described in detail in Ser. No. 347,500, and it is unnecessary to go into the circuitry therein as these components form no part of the present invention. However, it is important to note that the pump control circuit produces a signal on each of the pumping and withdrawal strokes of the heart pump, the duration of which dictates the length of stroke of the pump and the magnitude of which dictates the speed of the heart pump during each stroke. The pump control signal is indicated by the numeral 12 and the withdrawal control signal is indicated by the numeral 13, both of which are supplied to a power switching amplifier 14.

A D.C. power supply of a suitable design delivers approximately 1,000 watts to the power switching amplifier 14 at a voltage level of approximately 50 v. D.C., these levels being merely exemplary. The power supply 15 may consist of an input transformer, a full wave rectifier, and conventional filtering if desired.

The power switching amplifier 14 drives alternatively the pump solenoid coil 16 and the withdrawal solenoid coil 17 in accordance with the values set by the surgeon or technician lin the MAIS control 10 and fthe pump control circuit 11. The solenoid coils 16 -and 17, described in more detail below, lare responsive to both the magnitude and duration of the signal from the power switching amplifier 14 to drive an actuating piston 18 at a preselected speed to a preselected length of stroke. The actuating piston 18 delivers and withdraws hydraulic fluid from a fluid coupling 19 which is connected to drive a bellows blood pump 20.

Referring to FIGS. 1 and 3, the power switching amplifier 14 consists of two transistor circuits 30, one for the pump stroke and one -for the withdrawal stroke, each having a power transistor 31 connected at its base to receive one of the pump or withdrawal control signals 12 or 13 from the pump control circuit 11. The pump solenoid coil 16 is connected to the collector of transistor 31 so that the amount of base current drive to the power switching transistor 31 dictates the collector current driving the solenoid coil 16 thereby controlling the magnitude and duration of the signal in the pump solenoid coil. While FIG. 3 is described with respect to the pump control signal, the identical operation applies to the withdrawal power switching transistor which is not shown. It is understood that the pump control circuit only energizes one of the power yswitching amplifier circuits 30 depending upon the direction in which the blood pump 20 is moving.

Viewing FIG. 2, an electric actuator 40 supplies hydraulic iiuid to the pump 20 and includes a push-pull type solenoid 41, a shaft 42 and the actuating piston 18. A housing 44 encloses all of the components of the electric :actuator 40. The solenoid coils 16 and 17 are mounted within a cylindrical bore 45 in one end of the housing 44 and are separated 'by la suitable retaining ring 46. The coils are secured in the cylinder or bore 45 by an end cap 47 which closes one end of housing 44. An armature 50 is slidably mounted within the coils 16 and 17 and includes a cylindrical core 48 mounted on an enlarged end of shaft 42. Annular grooves 53 `and 54 are formed in the housing 44 and define narrow saturating sections that direct the fiux path to achieve approximately linear force versus stroke in the solenoid 41. These sections limit the gap iiux when the armature reaches a position close to either end of the bore or cylinder 45. The amplitude of the signal in one of the coils 16 or 17 controls the speed of the armature 50 and thereby the rate of flow of fiuid delivered by the -actuator piston 18 to the pump 20. Also, the coils will continue to drive the armature 50 at the predetermined speed until the pump control circuit 11 switches the control signal to the other coil. This is in counter distinction to a positioning type system based upon the derivation of an error signal. A potentiometer 55 driven by a projection 58 on the shaft 42 produces a signal proportional to the length of stroke of the shaft which is fed back to the pnrnp control circuit 11 for controlling the length of stroke of the piston 18. A linear variable transformer may be `used equally well in place of the potentiometer 55.

The shaft 42 connects the armature 50 to the piston 18 and is constructed of a suitable nonmagnetic material, and has counterbores 56 and 57 adjacent the armature 50 and the piston 18 respectively, to eliminate weight which wou-ld otherwise cause mechanical time lags. Time lags are particularly undesirable in this system as the heart pump 20 must accurately be synchronized with the patients selected natural physiological parameter.

The actuating piston 18, formed integrally with shaft 42, is reciprocally mounted in a cylinder 60 in one end of the housing 44 and carries suitable sealing rings 61 and 62. The piston 18 divides the cylinder 60 into a working chamber 64 and a venting chamber 65. Chamber 65 is in continuous communication with the atmosphere through a vent 66 to prevent any back pressure on the piston 18.

The cylinder 60 is closed by an end cap 70 fastened to one end of the housing 44 by suitable means and has formed thereon a threaded nipple 71 which receives a threaded fitting 72 of the hydraulic coupling 19. The hydraulic coupling 19 includes a suitable iiexible hose 73 of a synthetic material such yas one of the plastics, and carries Ia threaded fitting 74 at its other end fastened to a threaded nipple 80 fonmed on the end of a cup-shaped housing member 81 of the bellows puimp 20.

The housing of the pump 20 includes the cup-shaped member 81, cylindrical housing member 82 and cupshaped member 83 secured together by suitable clamps (not shown). Housing members 81, 82 and 83 form a cylinder 84 therein which reciprocally receives a cylindrical floating piston 85. A bolt 86 extending through the piston holds clamping plates 87 and 88 against two rolling diaphragms 89 and 90 thereby sealing the diaphragms against both ends of the piston 85 and insures reliability in the pump. The 'diaphragms 89 and 90 form an annular chamber 92 between the piston 85 'and the housing member 82. Communicating with the annular chamber 92 is a passage 93 formed in the housing 82 which communicates at its lower end with the interior of a cylinder 95 integrally formed with housing member 82. The cylinder 95 receives an evacuating piston 97 having a thumb screw 98 rotatably mounted therein. The lower end of the thumb screw 98 has a threaded portion 99 iadapted to engage threads 100 on a cylinder end cap 101 fixed to the cylinder 95. A spring 102 urges the evacuating piston 97 downward. In the upper portion of the housing member 82 a passage 105 formed therein cornmunicates with the annular passage 93 and a fill cap 106.

The evacuating piston mechanism serves to evacuate the annular chamber 92 and assures proper diaphragm rolling action. This mechanism is operated by threading the threaded portion 99 of the thumb screw 98 into the end -cap 101 compressing the spring 102 thereby expelling air :from cylinder 95, filling the chamber 92 with a blood compatible solution such as Dextran through passage 105, replacing the ll cap 106, backing out the thumb screw 98, disengaging the threads 99, thereby permitting the spring 102 to urge the piston 97 downward and thus maintain a low grade vacuum in chamber 93. The low grade vacuum applied by piston 97 insures proper diaphragm rolling action.

Piston 85 divides the cylinder 84 into chamber 110 and chamber 111. Chamber 110, uid coupling 19 and chamber 64 in the electric actuator 40 are lled with Dextran or another blood compatible fluid so that the chamber 111 and the patients circulatory system are isolated from any substance incompatible with the patients system.

A ll cap 109 is provided in pump housing member 81. Blood compatible iluid may be injected into the system through the reservoir 114. Air entrained in the duid is tforced out through air vent 112 in a cap 113 threaded in the reservoir 114 mounted on the upper portion of housing member 81. Cap 113, must be Unthreaded slightly to expose the vent 112, and may be threaded tightly so that during pumping no air may enter the system.

A vent 120 in a cap 121 threaded in the upper portion of housing member 83 permits air bubbles in the chamber 111 to be expelled from the system when the cap 121 is slightly unscrewed in a manner similar to cap 113. A blood supply reservoir 125 delivers blood through a valve 126 and a conduit 127 to working chamber 111 of the reciprocating pump 20, during priming of the chamber 111, but is normally shut off during the operation of the pump. Chamber 111 may be filled with blood compatible uid instead of blood.

Housing member 83 has an elongated portion 130 dening an outlet for the pump with an outlet passage 131 for the pump having a threaded portion 132 engaging threads on catheter tting 133. A flexible catheter 134 has branches 135 and 136 which are open ended.

In operation, the pump 20 is placed on the operating table between the lpatients legs and the catheter branches 135 and 136 are inserted into the patients femoral arteries and gently urged into the descending aorta. Other methods of insertion may be employed such as int-o the left sub-clavian artery. The desired length of stroke and speed of stroking are selected in the pump control circuit by the surgeon or technician and the MAIS control is c-onnected to receive the patients physiological signal. The electric actuator 40 is conveniently mounted in the console containing the MAIS control 10, the pump control circuit 11, and the power switching amplifier 14, all of which may be placed laway from the operating table. Only la single hydraulic line, i.e. conduit 73, runs from the console to the pump located at the operating table. The pump control circuit energizes withdrawal coil 17 and the piston 18 withdraws fluid from pump chamber 110 at Ka rate dictated by the magnitude of current in the coil. The piston 85, of course, accurately follows movement of the piston 18 because of the rigid fluid coupling therebetween. When `the piston reaches its desired length of stroke, the pump control circuit switches the current through the switching plier 14 to the pump coil 16 thereby reversing the direction of travel of the piston 18 and the pump piston 25. The piston 18 then travels toward the right in FIG. 2 in a similar manner as in the withdrawal stroke until the pump control Acircuit 11 terminates `the control signal 12. The pump control circuit 11 then awaits the next EKG input signal through the MAIS control before beginning a new pumping cycle. As the piston 85 reciprocates, it delivers and withdraws blood to and from the patients aor-ta through the catheter 134 in the same manner las described in Ser. No. 347,500.

Having thus described an exemplary embodiment of my invention, what s claimed as new and desired to secure by Letters Patent of the United States is:

f1. A heart augmentation system, comprising:

a free piston bellows pump having iirst and second chambers therein, said rst chamber adapted Ifor connection to a catheter Ifor insertion into ya patient [and for communicating blood thereto;

a reciprocating pump having 'a pis-ton working in a drive chamber, said pump having a suction stroke and pressure stroke adapted to draw fluid into and eject iluid lfrom said drive chamber, respectively;

and la pressurized fluid communication iline between the drive chamber of said reciprocating pump and the second chamber of said bellows pump, said line coupling the action of said reciprocating pump to said second chamber of said bellows pump so that blood is forced into 'and' out -of said rst 'chamber of said bellows pump in response to iluid pressure communicated to the second chamber of said belllolws pump by said reciprocating pump through said 2. In la he-art -augmentation system as defined in claim 1 means connected to said iirst chamber of said bellows pump for supplying additional blood to the circulatory system.

3. A heart augmentation system Iaccording to claim 1 additionally comprising:

ya switching lamplifier lfor controlling the ilow of the current to said electric solenoid;

|and a control circuit connected to said switching ampliiier Isynthesizing the desired characteristic-s of said bellows pump.

4. A heart augmentation system according to claim 1 wherein said reciprocating actuator pump :further comprises:

a housing of magnetic material having an armature slida-bly mounted therein;

rst and second coils in said housing `for moving said armature in respective first and second directions, said coils and said armature comprising the driving solenoid for said `actuator pump, relative movement of the 'armature being responsive to the magnitude of the current in said coil;

said drive chamber comprising a cylinder located within said housing, said armature being rigidly connected `to said piston;

said housing having annular grooves adjacent said rst Iand second coils yfor maintaining a substantially -linear relation 'between the @force on the armature and the rate of movement `of the armature.

5. In a heart augmentation system for assisting natural heart action; a catheter adapted to be inserted into the patients circulatory system, a pump connected to said catheter having a pump and a withdrawal stroke Yfor supplying blood to the circulatory system; an electric actua-tor `for controlling movement of the pump including a housing having two chambers therein, a pump coil and =a withdrawal coil mounted in one of said chambers, an armature having windings thereon reciprocally mounted in said one chamber, the other of said chambers defining a cylinder, an actuator piston mounted in said cylinder, a

shaft rigidly connecting the armature and the actuator piston, saturation means `for controlling the flux path, and an outlet in said other chamber adjacent said piston; and a flexible conduit connecting said outlet to said pump having hydraulic fluid therein thereby providing a rigid fluid coupling between the actuator and the pump.

6. In a heart augmentation system a catheter adapted to be inserted into the patients circulatory system, a blood pump connected to said catheter having a reciprocating piston; an actuator for controlling movement of the pump piston including a housing having two chambers therein, a pump coil and a withdrawal coil mounted in one of said chambers, an armature reciprocally mounted in said one chamber within said coils, said armature having a stroke rate responsive to the magnitude of current in said coils, said larmature also having a hollow section to reduce the delay time of the actuator, the other of said chambers defining a cylinder, an actuator piston mounted in said cylinder and adapted to deliver and withdraw uid from said reciprocating pump, said actuator piston being rigidly connected to said armature, a hollow section within said piston to reduce the `delay time of the actuator, grooves in the housing adjacent the pump and withdrawal coils for controlling the ux path between the coils and the armature, and an outlet fitting in said other chamber adjacent said actuating piston; and `a fluid coupling connecting lsaid outlet fitting and said blood pump.

7. In a heart augmentation system the combination of; a catheter adapted to lbe inserted into the Ipatients circulatory system; a pump for supplying blood to the circulatory system including `a housing vhaving la first end member, a central member, and a second end member xed to said central member, a cylinder in said housing, a oating piston slidably mounted in said cylinder, a first diaphragm mounted between said rst end section and said central section on one side of said piston, a second diaphragm mounted between said central section Iand said second end section on the other side of said piston, means on the housing for evacuating the space between the diaphragms thereby eiecting a rolling 'of the diaphragm reciprocation of the piston, a fitting member on said second end section connected to the catheter adjacent the working end of the piston, fa second fitting on said first section of the housing adjacent the driven end of the piston; an electric actuator for [driving the blood pump piston including a housing having two chambers, pump and withdrawal coils mounted in one of said chambers, an armature slidably mounted in said one chamber adjacent said coils, an actuator piston connected to said armature and adapted to 'deliver fluid to one end of the blood pump piston, said actuator piston being rigidly connected to said armature; =a uid coupling connecting said actuator piston and said second fitting whereby the pump piston is driven by the actuator, and control circuit means for altern-atively energizing said coils and controlling the magnitude of current to said coils to vary the speed of movement and length of movement of the armature and the pump.

8. A reciprocating pump lfor a heart augmentation system comprising a housing, a piston reciprocally mounted in said housing, a first diaphragm mounted in said housing covering one end of said piston, a second diaphragm spaced from said first diaphragm mounted in said housing and covering the other end of said piston, and means to evacuate the lspace between said diaphragms, said evacuation means comprising a piston and cylinder mounted -adjacent said housing.

9. A reciprocating pump for a heart augmentation system as defined in claim 8 wherein said means to evacuate the space between the diaphra'gms includes -an opening through said housing communicating with said 4space permitting uid to be injected in said space, a closure for said opening, a cylinder mounted on said housing communicating with said space, an evacuating piston slidably mounted in said cylinder, resilient means urging said piston toward one end of the cylinder in a direction to evacuate said cylinder, and means rfor holding said piston at the other end of said cylinder so that the space between the ldiaphragms ymay be filled with fluid and closed before the resilient lmeans evacuates the space.

10. A reciprocating pump Ifor a heart augmentation system as defined in claim 8 wherein said means to evacuate the space :between the diaphragms includes an opening `through said housing communicating with said space permitting fluid to be injected in said space, a closure for said opening, a cylinder mounted on said housing com municating with said space, an evacuating piston slidably mounted on said cylinder, a spring mounted in said cylinder engaging said piston to one end of the cylinder in a direction to evacuate `the cylinder, a -member rotatably mounted in one end of the piston and having a threaded portion engaged with said one end of the cylinder, said threaded portion being spaced from said one end of said piston whereby when the threads are engaged, the spring is compressed and air is exhausted from the cylinder.

References Cited UNITED STATES PATENTS 799,064 9/ 1905 Kowsky 60-545 2,725,078 11/ 1955 Glancy. 3,099,260 7 1963 Birtwell 128-1 3,162,134 12/1964 Lovell 310-18 3,233,687 2/ 1966 Bolie 128-64 3,266,487 8/1966 Watkins et al. 128--1 FOREIGN PATENTS 292,203 6/ 1928 Great Britain.

OTHER REFERENCES Moudopolous et al.: Extra Corporal Assistance to the Circulation and Intra ortie. Balloon Pumping Trans. American Soc. Artificial Internal Organs, vol. VIII, April 1962, pp. -87.

DALTON L. TRULUCK, Primary Examiner.

U.S. Cl. X.R.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US799064 *Sep 5, 1902Sep 12, 1905Hans KowskyPneumatic or hydraulic transmission of electric power.
US2725078 *Jun 27, 1951Nov 29, 1955Glancy Walter PFlexible liner assembly for a fluid pressure device
US3099260 *Feb 9, 1960Jul 30, 1963Davol Rubber CoHeart pump apparatus
US3162134 *Nov 24, 1961Dec 22, 1964Lovell Mark EElectromagnetic pump and energizing means therefor
US3233687 *Mar 22, 1963Feb 8, 1966Jay Grimes HomerDrop hammer
US3266487 *Jun 4, 1963Aug 16, 1966Sundstrand CorpHeart pump augmentation system and apparatus
GB292203A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3769960 *Apr 17, 1972Nov 6, 1973Us Health Education & WelfareIntra-aortic balloon system
US4046137 *Aug 11, 1976Sep 6, 1977Avco CorporationSolenoid operated blood pump drive system
US4236880 *Mar 9, 1979Dec 2, 1980Archibald Development Labs, Inc.Nonpulsating IV pump and disposable pump chamber
US4322201 *Sep 21, 1979Mar 30, 1982Avi, Inc.IV Pump with back pressure control
US4382753 *Sep 10, 1980May 10, 1983Avi, Inc.Nonpulsating IV pump and disposable pump chamber
US4391600 *Sep 15, 1980Jul 5, 1983Avi, Inc.Nonpulsating IV pump and disposable pump chamber
US4410322 *Sep 10, 1980Oct 18, 1983Avi, Inc.Nonpulsating TV pump and disposable pump chamber
US4611578 *Apr 27, 1984Sep 16, 1986Forschungsgesellschaft fur Biomedizinischs Technik E.V. GoethestrasseRedundant piston pump for the operation of single or multiple chambered pneumatic blood pumps
US4857048 *Mar 21, 1988Aug 15, 1989Hewlett-Packard CompanyIV pump and disposable flow chamber with flow control
US4950134 *Dec 27, 1988Aug 21, 1990Cybor CorporationPrecision liquid dispenser
US5090299 *Jun 13, 1990Feb 25, 1992Tetra Dev-CoPiston unit with rolling membrane
US5320503 *Sep 23, 1993Jun 14, 1994Patient Solutions Inc.Infusion device with disposable elements
US5490765 *May 17, 1993Feb 13, 1996Cybor CorporationDual stage pump system with pre-stressed diaphragms and reservoir
US5527161 *Aug 3, 1994Jun 18, 1996Cybor CorporationFiltering and dispensing system
US5584667 *Jun 6, 1995Dec 17, 1996Davis; David L.Method of providing uniform flow from an infusion device
US5803712 *Feb 14, 1995Sep 8, 1998Patient Solutions, Inc.Method of measuring an occlusion in an infusion device with disposable elements
US5885244 *May 14, 1997Mar 23, 1999Cordis Corporation & University Of MiamiSynchronous, pulsatile angioplasty system
US6146109 *Jun 29, 1998Nov 14, 2000Alaris Medical Systems, Inc.Infusion device with disposable elements
US6312227Mar 30, 1993Nov 6, 2001I-Flow Corp.Infusion device with disposable elements
US6672841 *Mar 26, 1998Jan 6, 2004Fresenius Medical Care Deutschland GmbhPumping and metering device
US6742992Nov 7, 2002Jun 1, 2004I-Flow CorporationInfusion device with disposable elements
EP0124102A2 *Apr 27, 1984Nov 7, 1984Forschungsgesellschaft für Biomedizinische Technik e.V.Redundant piston pump for the operation of single or multiple chambered pneumatic blood pumps
WO1980001934A1 *Mar 3, 1980Sep 18, 1980Archibald Dev LabNonpulsating iv pump and disposable pump chamber
Classifications
U.S. Classification600/17, 604/67, 92/98.00D, 604/152, 417/383, 417/375
International ClassificationA61M1/10
Cooperative ClassificationA61M1/1081, A61M1/1086, A61M1/1037
European ClassificationA61M1/10F, A61M1/10R