|Publication number||US3470876 A|
|Publication date||Oct 7, 1969|
|Filing date||Sep 28, 1966|
|Priority date||Sep 28, 1966|
|Publication number||US 3470876 A, US 3470876A, US-A-3470876, US3470876 A, US3470876A|
|Original Assignee||John Barchilon|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (11), Referenced by (329), Classifications (19)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Oct. 7, 1969 J. BARcHlLoN DIRIGIBLE CATHETER 4 Sheets-Sheet 1 Filed Sept. 28, 1966 INVENTOR BmfcMon John 3f Momo/Mq DI w wg ATTORNEYS Oct. 7, 1969 J. BARCHILON DIRIGIBLE CATHETER 4 Sheets-Sheet 2 Filed Sept. 28, 1966 John Boxdmbh BY .910160 wwbxqww ATTORNEYS Oct. 7, 1969 J. BARcHlLoN DIRIGIBLE CATHETER 4 Sheets-Sheet 5 Filed sept. 2a. 196e INVENTOR Bcxvch \ov1 John BY Dafo ATTORNEYS Oct. 7, 1969 J. BARcHlLoN DIRIGIBLE CATHETER 4 Sheets-Sheet 4 Filed Sept. 28, 1966 INVENTOR BY ma@ a www@ ATTORNEYS United States Patent O 3,47 0,876 DIRIGIBLE CATHETER John Barchilon, 436 E. 69th St., New York, N.Y. 10021 Filed Sept. 28, 1966, Ser. No. 582,624
Int. Cl. A61m 25 00; A61b 5/10 U.S.y Cl. 128--348 `9 Claims ABSTRACT F THE DISCLOSURE This disclosure relates to a dirigible catheter having This invention relates to catheters, and more particularly relates to dirigible catheters.
A catheter is basically a tube-like member insertable into a body passage or cavity which may be used for drawing off samples, or for other medical purposes. This invention relates to such devices and providesI a new and improved catheter which is guidable through 360 degrees.
Cathetens which have been capable of some guidance in direction of the distal end from the proximal end have heretofore been proposed. Such proposed guidance was usually accomplished by one tensioning member in the form of a wire or cord which extended along the length of the catheter within its innerv channel or bore, Wasattached adjacent the distal end of the catheter, and tensioning the cord from the proximal end of the catheter would bend the tip or distal end of the catheter in one direction.
Additionally, some 'catheters have been proposed which require such a tensioning cord as a guide means .but offset the bore of the catheter. Such construction resulted in extremely thick walls of the catheter and, therefore, reduced the bore thereof and its usefulness.
A catheter must be highly flexible so that it can be turned upon itself, yet sufficiently rigid to be Ipushed from its proximal end without kinking upon itself. Its external diameter is limited both by the passage in whichl it must be inserted and by the requirements for strength and longitudinal rigidity required for insertion and manipulation.
The present invention provides a new and improved thin-walled catheter which has a high ratio of bore or lumen dimension to overall diameter. Tlhe structure of this catheter is such that :both the outer walls and the inner walls la-re smooth and cylindrical, and the bore is concentric with the outer cylindrical walls. However, the walls have such strength as to Ireceive a plurality of tension means therein Ito allow the distal end thereof to be guided from the proximal end through 360 degrees freedom of motion.
Moreover, the construction is such that the guide lines may be simultaneously manipulated to easily guide the distal end of the catheter. The structure is further such that the walls may be made thin to maximize the ratio of the external diameter to the internal diameter. The invention Ifurther provides a catheter having a continuous bore of constant diameter concentric with the lou-ter walls and having no obstructions therein which would hinder maximum utilization of the catheter.
Accordingly, an object of this invention is to provide a new and improved catheter.
Anotlher object tof this invention is to provide a new and improved catheter having an increased ratio of internal diameter to `external diameter.
A further object of this invention is to provide a new and improved catheter having a distal end which is Idirigible through 360 degrees of motion.
Another object lof this invention is to provide new and improved means lfor guiding the distal end of a catheter from the proximal end thereof.
Further objects and `advantages of the invention will in part Ibe pointed out and in part be made apparent from the following description.
The features of the invention which are believed to be novel are set forth with particularity and Idistinctly claimed in the concluding portion of this specification. However, the invention both as to its organization and operation, together with further objects and advantages thereof may best be appreciated by reference to the following detailed description taken in conjunction with the drawings, in which:
FIG. l is a view in longitudinal section of a catheter embodying the invention;
FIG. 2 is 'a `sectional View seen in lthe plane of lines 2-2 of FIG. 1;
FIG. 3 is a view of a catheter embodying the invention together with the guidance mechanism therefor;
FIG. 4 is an enlarged view of the operating mechanism of the catheter of FIG. 3 shown partly in section;
FIG. 5 is a view seen in the plane of lines 5-5 of FIG. 4;
FIG. 6 is a view seen in the plane of lines 6 6 of FIG. 4;
FIG. 7 is an enlarged view of a portion of the operating mechanism shown in FIG. 4;
FIG. 8 is a lsectional view seen inthe plane of lines 8 8 of FIG. 7;
FIG. 9 is a view in half section of another operating mechanism Ifor t-he catheter of FIG. 1;
FIG. 10 is a sectional view seen in the plane of lines 10--10 of FIG. 9;
FIG. 11 is a view in section of a portion of the operating mechanism of FIG. 9; and
FIG. 12 is a schematic diagram showing the circuit connections for the operation of the mechanism of FIG. 9.
A catheter embodying the invention is generally indicated by the reference numeral 10 and comprises an outer cylindrical wall member 11 which is continuous along the length of the catheter 10. At the distal end 12 of catheter 10 is a tip or end piece 13 of fairly rigid material having an inwardly directed flange-like portion 14 which ts over the end of the inner catheter tube 15, and which further has a cylindrical portion 16 surrounding the inner catheter tube 15 at the distal end thereof and wlhich is bonded thereto. The member 13 further 'has a flange 17 thereon which receives guiding or tensioning cords 18a, 18b, 18C and 18d. These cords or lines are fastened to ange 17 to prevent being pulled therefrom, as by enlargement of the ends thereof by knotting of end pieces attached thereto. The cords extend through tube-like members, 19a, 1911, 19e and 19d, disposed at 90 degrees with respect to eacih other within the catheter body. A nose piece 20 is disposed about member 13 and extends back to a body member 21. Member 20 may be recessed as at 22 to enhance freedom of movement of the cords 18. Body member 21 may be formed with a shoulder 23 adapted to receive thereon the end of nose piece 20, and provide a continuous outer diameter therewith.
The catheter 10 is assembled by disposing tubes 19a and 191) about inner catheter tube 15 at 90 degrees around Uhe circumference of tube 15. This assembly is then molded within member 21 which is of a suitable exible material. One such material which has been found to have been satisfactory is a silicone compound RTV 11 of the General Electric Company. The inner tube 15 and tubes 19a- 19d'are chosen to be exible, and suitable materials have been found to be polyethylene or vinyl. During this molding operation a reinforcing sleeve of a suitable mesh material 24 is preferably disposed about the catheter tube 15 and the guide tubes 19a-19d and molded within member 21 to provide reinforcing if deemed necessary.
The member 13 is then fitted over the distal end of tube 15 and the guide or tension cords 18 may be attached and threaded through tubes 19. Member 20, which has previously been molded of similar compound as member 21, is then iitted over member 13 and extended into the shoulder 23 on member 21. Then the outer tubing 11 which has been separately molded is slipped over members and 21 to provide a smooth outer surface which is continuous throughout its length.
This construction provides a catheter which is continuous and of constant cross-section throughout its length except for the rounded distal end 12. Further, the inner tube 15 is of constant cross-section throughout its length with no obstructions therein and defines the inner catheter passage or lumen 26.
The catheter tube described may be varied in length from less than one foot to more than thirty feet, depending upon its usages which may be to inject radiopaque dyes quickly to points where lesions are suspected. Barium can be squirted directly in the region of the duodenal bulb, or the ascending colon. The catheter is further ideal for transporting a highly flexible, but rather unwildy, fiberscope. For example, a catheter could be passed into the tracheobronchial tree and with the berscope, a suspected epithelial lesion could be located. Furthermore, when the catheter is in the proper position, suction could be applied and cells can be aspirated for a cytological examination.
The cross-sectional diameter may vary from between one-eighth inch up to two inches, again depending upon its desired use. The inner diameter will vary correspondingly, but will generally be about sixty percent or more of the outer diameter.
The materials of the catheter tube are made of flexible compounds such that it can be bent and turned on itself to make right angle turns and conform to pretzel congurations. Its tiexibility range is such that it is suliiciently rigid to be pushed from its proximal portions -without kinking on itself, and at the same time exible enough to make the above-mentioned bends. The specific flexibility of the material will vary depending on its intended use. The previously mentioned General Electric Company RTV 1l silicone compound has a durometer of 48. The catheter tube itself is not subjected to tension greater than that required to pull or push it. The guide lines 18 running within its walls may be subjected to approximately twenty pounds of pull, depending upon the use of the catheter. These guide lines 18 may be made of wire, nylon, surgical silk or other suitable materials. It has been determined that the above-mentioned material can be autoclaved at 250 degrees Fahrenheit for forty-five minutes, which is more than sutlicient to assure its sterility.
Returning to FIGS. l and 2, it may be seen that tensioning one or more of the guide cords 18 will produce bending of the distal end of the catheter 10 as represented by the broken line 27. For example, the bending of the distal end shown in FIG. 1 may result from merely applying tension to the 180 degree line 18e which would exert a pull downwardly as shown in FIG. l on the ange 17 of member 13. By selectively tensioning different ones of lines 18a-18d the distal end may be directed in any direction throughout 360 degrees with respect to a plane perpendicular to the axes thereof.
Reference is now made to FIG. 3 which shows the Catheter 10 mounted to a manipulating device 30 which contains a mechanism for selectively operating `the cords 18a-18d. The manipulating device is exemplified in the form of a member having a pistol grip 31 which has a passage 32 defined therethrough which is coaxial and of essentially the same size as lumen 26.
The catheter `tube 11 is coupled to the `assembly 31 by means of an adaptor 34. Adaptor 34 at one end thereof has longitudinally extending lfingers 35 defined by longitudinally extending slits 36 therein, and is threaded at 37 to receive a chuck-like member 38. Adaptor member 34 further includes a collar-like member 39 received in an undercut 40 therein which has internal threads 41 adapted to mate with threads 42 on the exterior of barrel 43. To assemble the catheter tube to the handle and operating assembly, the lines 18a-18d are connected to mating lines 18a-18d' extending from an operating mechanism, hereinafter described, as by means such as hook and eye connectors 44. Then adaptor 34 is fitted to barrel 43 and has an intercocking tit as indicated at 45 therewith. Then the collar-like member 39 is threaded on t-o handle member 30 and the adaptor is made fast to handle `30.
Then the catheter tube is pulled outwardly of adaptor 34 to tension the lines 18a-18d so that there is no slack therein, and all lines are equally tensioned with the distal end of the catheter tube unbent. At this time, chuck-like member 38 is threaded tightly on to adaptor 34 so that the inclined portion 38a of chuck-like member 38 rides up over lingers 35 and compresses lingers 35 about the catheter tube. This compression of the fingers 35 about catheter tube 11 `holds it securely in place and prevents either longitudinal or rotational movement thereof with respect to barrel 43.
The lumen of catheter 10 is now coaxially aligned with the passage 32 dened in 'barrel 43.
Disposed within barrel 43 is a bushing or sleeve-like member 46 which acts as a guide for lines l8a'-18d extending from a guiding cont-rol mechanism 47. The function of sleeve 46 is to space the guide lines 18a-18d' as they change from a generally inclined direction with respect to the lumen of the catheter to a direction which is parallel of the axis -of the lumen of the catheter. This further provides a clear access to the lumen through the barrel 43. This is more clearly shown in FIG. 6. It will be noted that the line 18a must cross passage 32 without adding an obstruction thereto. This is done by gently curving line 18a in a helical path about the bushing or sleeve 46, and for this purpose such Ia path may be dened therein. In this manner, appropriately contoured passages may be defined in the exterior periphery thereof yfor any yor all of line 18a18d as may `be required.
The catherter guidance mechanism 47 is more clearly shown in FIGS. 6-8. This mechanism provides a means for guiding the distal end of the catheter through 360 degrees projected on one plane.
The lines or cords 18a and 18C', and 18b' and 18d are in continuous pairs, each pair disposed about a wheel which upon rotation thereof tensions one line of a pair and releases tension in the other line of the pair.
The guidance mechanism 47 comprises a base member in the form of a plate 49 having `an aperture defined therethrough which receives a ball 50. Ball `50 is vrotatable in plate 49 and retained in position with respect thereto by upper and lower -retaining plates 51 and 52. Extending through ball 50 is 1a shaft 53 having a trimble-like end piece 54 adapted to receive a iinger for manipulation of shaft 53.
Shaft 53 extends through an opening 55 delined by two pairs of half ring members 56, 57; and `58, 59, disposed perpendicular to each other. Members 56 and 57 are secured at their ends to coaxi-al shafts `and 61 which are rotatably carried in brackets 62 and 63, respectively, which are in turn carried on plate 49. Similarly, members 58 and 59 are secured to shafts 64 and 65, rotatably carried in briackets 66 and 67, mounted on plate 49.
Mounted to shafts 61 and 65 are gears 68 and 69, respectively. Also rotatably carried in brackets 62 and 67 are shafts and 71, respectively. Mounted to shaft 70 is a gear 72 in meshing engagement with gear 68. When vgear 72 is driven by gear 68 it'rotates a sheave 'or wheel 73. Mounted to shaft 71 is a gear 74 and wheel 7S. When gear 69 rotates gear 74 it also rotates a sheave or wheel 75.
Disposed about wheel 73 are lines 18b' and 18d. Disposed about Wheel 75 are lines 18a and 18e.
In operation, it may be seen that when 'shaft 53 is manipulated it will act against one or both pairs of members 56, 57 or 58, 59 and produce rotation of'one or both of shafts -61 and/or 65. This will produce resultant rotation of one or both of wheels 73 and 75.l Wheel 73, about which is wound lines 18b and 18d, upon rotation thereof, will tension one of the lines and provide slack in the other of the lines. Similarly, rotation of wheel 75 will tension oneA of lines 18a or 18e and provide slack in the other of the lines. "llherefore, any two of lines 18a through 18d residing at righ-t angles to each other may be simultaneously tensioned to exert a pulling force on member 1,3 and, therefore, bend and guide the distal end of the catheter through 360 degrees.
It may thus be seen that this operating mechanism, While providing 360 degrees of motion at the `distal end of the catheter tube, allows the gui-de lines which are 180 degrees apart to be tensioned and slacked simultaneously, and fur-ther provides that varying amounts of tension may be applied to the guide lines which are 90 degrees apart .to bend and position the distal end of the catheter Iat any angle.
While the degree of motion has been spoken of as 360 degrees, it will be understood that this refers to 360 degress in one plane which is perpendicular to the axis of the catheter in its relaxed position, and further provides for three-dimensional positioning of the distal end of the catheter with respect to such 360 degrees.
Other techniques of selectively tensioning one of a pair of the guide lines may be utilized. FIG. 9 shows an alternate embodiment 4which works on 4an electromagnetic principle. In FIG. 9 each of the lines '18a-18d are connected to the plungers 80er-80d of electromagnets having coils 81a-81dgDependent upon the magnitude of energization of the coils, the plungers therein will either advance as shown in FIG. 9 or be retracted towards the left. Each of the electromagnets is disposed 90 degrees with respect t-o the axis of the catheter within a housing member 82 having Aa bore 83 coaxial with the catheter lumen.
The electromagnets are selectively energized through a mechanism similar to that shown in FIGS, 6-8. This mechanism lis illustnated in fFIG. 11 and like reference numerals to those used in FIGS. 6-8 identify like elements in FIG. 11. In the mechanism 84, the shaft 61 has mounted thereto the contact arm 85 of a potentiometer 86. The shaft 65 carries a contact arm 87 of a potentiometer 88.
The circuit connection to the potentiometers 86 and 88 with coils 81a-81d are shown in FIG. 12. It will be noted that the current from va-source such as battery 89 is applied to both of the contact arms 85 and 87, and when these contact arms are on the midpoint of the resistance of potentiometers -86 and 88 all coils will be equally energized and the tension in all 0f lines 18a-18d will -be equal. However, when the contact arms are displaced as 'shown in FIG. l2, coils 81a and 81b will receive more current than coils y81C and 81d, respectively. Therefore, lines 18a and 18d will be tensioned with respect to other lines and the distal end of the catheter will be guided in a quadrant dened by the lines 18a and 18b.
It may thus be seen that by proper manipulation of shaft S3 with one tinger, the distal end of the catheter may be guided through 360 degrees, and provides continuous three-dimensional vectonal resolution to coordinate axes. Preferably, a pistol-type grip las illustrated is used to handle the manipulation assembly so that the distal end of the catheter may be guided through use of one dinger.
The disclosed catheter may have many applications. 'For example, in radiology, the catheter provides a means by way of which radiopaque dyes can be injected quickly to points where lesions are suspected. The disclosed catheter is ideal for transporting the highly flexible, but rather unwieldy fiberscope. In another embodiment of the invention a Ifiber-scope could be incorporated into the walls of the catheter and the catheter lumen would be then used for providing instrumentation. For example, the catheter with la built-in iiberscope could be passed into the tracheobronchial tree and a suspected epithelial lesion located. Then suction could be applied to the region in question and cells coul-d be aspirated for cytological examination. Further, this catheter would be useful in pulmonary embolectorny. Once the ldisclosed catheter, for example, with a fiberscope therein is utilized to locate an embolus (cardiac catheterization and injection of radiopaque dye under iiuoroscopy) a second catheter, the embolectomy catheter, which consists of a small plastic drill piece Iwould be utilized to break up and drive the thrombus linto the catheter. Suction applied :at pressures greater than right ventricular systole would cause bits of thrombus to be sucked back through the embolectomy catheter. Additionally, the embolectomy catheter could be utilized for taking small samples which would be drawn back into the disclosed catheter.
From the foregoing disclosure, it may be seen that the objects of the invention set lorth as well as those made apparent `from the preceding `description are ediciently attained. While presently preferred embodiments of the invention have been set -forth for purposes of disclosure, other embodiments of the invention and modilications to the disclosed embodiments which do not deplamt from the spirit and scope of this invention may oc cur to others skilled in the art. Accordingly, the appended claims are intended to cover all embodiments of the invention as well als modifications to the disclosed embodiments of the invention which do not depart from the spirit 'and scope thereof.
What is claimed Lis:
1. A catheter comprising a flexible elongated tube hav ing a proximal end and a distal en-d adapted to be inserted into a body passage, said tube having a continuously smooth outer `surface `and continuously smooth inner walls defining a continuous unobstructed passage from said proximal end to said distal end, a plurality of guide lines anchored adjacent the distal end of said tube and equiangularly between the walls defining the passage and the outer surface of the catheter, said lines being longitudinally movable with respect to said tube, said lines being four in number and disposed degrees about said catheter, the lines degrees apart forming a pair, to means for tensioning said lines including means for simultaneously tensioning one line of a pair and releasing tension in the other line of a pair.
2. The catheter of claim 1 wherein said catheter -further comprises an inner tube derning the continuous passage 'and an |outer |tube defining said outer surface spaced from said inner tube, said lines being disposed .about said inner tube, means secured to said inner tube adjacent the distal end thereof, land said lines being anchored to said coupling means.
3. The catheter of claim \1 wherein said means for tensioning comprises electrornagnetically operated means connected to each of said lines, energizing means for said electromagnetically operated means, said energizing means being differentially connected so that as the tension in one of said lines of a pair is increased the ten-sion in the other of the line of a pair is decreased.
4. An elongated tube-like member comprising -an inner exible tube member having a smooth, continuous inner wall, an outer flexible tube member disposed about said inner tube and having a s-mooth continuous outer surface, means coupling said tubes at the distal ends thereof, our `guide lines disposed at 90 degrees with respect to each 7 other between said tubes and securedlto Said coupling means, and means `for selectively tensioning two lines and releasing 'tension the lines 180 `degrees therefrom.
5. The apparatus of claim 4 wherein said coupling means comprises a member disposed about and secured to said inner tube and having an annular flange adapted to receive said lines.
6. A catheter comprising an elongated flexible tube member having proximal and distal ends, two pairs of force-producing lines extending alongsaid member between said proximal and distal ends, the lines of said pairs being spaced substantially 180 degrees apart so that Said exible member may be caused to bend by exerting a force on one line of a pair and releasing force on the other line of a pair, electromagnetically operated force-producing means for each of said lines, means connecting each of said lines to one of Said electromagnelically operated means, and energizing means for simultaneously operating two of said electromagnetically operated means to release forced on one line of a pair and apply force to another line of a pair.
7. The apparatus of claim 6 further including means for simultaneously energizing all of said electromagnetically operated means in pairs.
8. The apparatus of clairn 6 wherein Said electromagnetically operated means comprise two pairs of electromagnets having magnetic elements movable in a direction and magnitude dependent on the strength of a magnetic eld applied thereto, means for producing magnetic elds for each of said magnetic elements and means for simultaneously Strengthening the field of one electromagnet of a pair and weakening the field of the other electromagnet of a pair.
9.*The apparatus' of claim 6 wherein said energizing means for each pair of lines includes a potentiometer having a resistance and contact arm, each pair of energizing means` being .connected to opposite ends of one potentiometer resistance and differentially energized therethrough dependent of the position` of the Contact arm on said re- Sistance, and means connected to Said contact arms to allow simultaneous and independent movement of the contact arm of each potentiometer.
References Cited UNITED STATES PATENTS 2,432,869 12/1947 Elmer 244-87X 2,453,862 11-/1948 Salisbury 128-9 2,498,692 2/1950 Mains 128-348 2,836,253 5/1958 Lovell 18o-27 2,975,785 3/1961 Sheldon 128-6 3,058,473 10/1962 Whitehead 128-349 3,091,235 5/1963 Richards 128-6 3,183,410 5/1965 Fiora 335-268 x 3,190,286 6/1965 Stokes 128-6 3,162,214 12/1964 Bazinet 128-4 `FOREIGN PATENTS 548,462 10/1942 Great Britain.
DALT ON L. TRULUCK, Primary Examiner U.S. Cl. X.R.
'(gjtlgo UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION Patent No. 3, l470 876 Dated October 7 1969 Invencor(s) John Barchi lon It is certified that error appears in the above-identified patent and that said Letters Patent are hereby corrected as shown below:
r- Column 6, line 52, after "pair," delete the word "to" and substitute therefor and Column 7, line 20, delete "forced" and substitute therefor force SIGNED ND SEALED JUN 9 1970 'ximvvjl'Ufnn'a f. r. .jgmgj' ,mxm (SEAL) Auen:
WIIILIAM E? ISGHUYIIER, J'R. r. Edvard Mjitcher'] Commissioner of Patents Atteating cer
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2432869 *||Mar 29, 1945||Dec 16, 1947||Westinghouse Electric Corp||Steering control solenoid structure|
|US2453862 *||Jun 2, 1947||Nov 16, 1948||Salisbury Peter Frederic||Gastroscope|
|US2498692 *||Jan 4, 1949||Feb 28, 1950||Mains Marshall Paul||Gastrointestinal tube|
|US2836253 *||Apr 12, 1954||May 27, 1958||Jac M Lovell||Automatic golf caddy vehicle|
|US2975785 *||Sep 26, 1957||Mar 21, 1961||Bausch & Lomb||Optical viewing instrument|
|US3058473 *||Nov 27, 1959||Oct 16, 1962||Whitchead Alfred E||Remotely directing catheters and tools|
|US3091235 *||Jun 15, 1960||May 28, 1963||American Optical Corp||Diagnostic instruments|
|US3162214 *||Jan 16, 1963||Dec 22, 1964||American Optical Corp||Flexible tubular structures|
|US3183410 *||Dec 30, 1960||May 11, 1965||Ibm||Magnetic multipositioning actuators|
|US3190286 *||Oct 31, 1961||Jun 22, 1965||Bausch & Lomb||Flexible viewing probe for endoscopic use|
|GB548462A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3625200 *||Aug 26, 1969||Dec 7, 1971||Us Catheter & Instr Corp||Controlled curvable tip member|
|US3631848 *||Sep 4, 1968||Jan 4, 1972||Us Catheter & Instr Corp||Extensible catheter|
|US3788304 *||Jun 15, 1971||Jan 29, 1974||Olympus Optical Co||Endoscope|
|US3892228 *||Oct 3, 1973||Jul 1, 1975||Olympus Optical Co||Apparatus for adjusting the flexing of the bending section of an endoscope|
|US3913565 *||Apr 25, 1974||Oct 21, 1975||Olympus Optical Co||Guide tube for a treating instrument to be inserted into body cavity|
|US4150676 *||Jul 1, 1975||Apr 24, 1979||National Catheter Corp.||Endotracheal tubes with intubation direction control means|
|US4353358 *||Aug 28, 1980||Oct 12, 1982||Emerson Reynolds L||Sigmoidoscope|
|US4475902 *||Mar 23, 1982||Oct 9, 1984||Werner Schubert||Device for introducing medical instruments into a body|
|US4586923 *||Jun 25, 1984||May 6, 1986||Cordis Corporation||Curving tip catheter|
|US4589410 *||Jul 15, 1985||May 20, 1986||Miller Larry S||Endotracheal tube|
|US4650467 *||Aug 22, 1985||Mar 17, 1987||Sarcem S.A.||Remote control catheter|
|US4677990 *||Feb 25, 1986||Jul 7, 1987||Siemens Aktiengesellschaft||Endocardial electrode controllable to form selected contours|
|US4685457 *||Aug 29, 1986||Aug 11, 1987||Donenfeld Roger F||Endotracheal tube and method of intubation|
|US4714075 *||Feb 10, 1986||Dec 22, 1987||Welch Allyn, Inc.||Biopsy channel for endoscope|
|US4723936 *||Jul 22, 1986||Feb 9, 1988||Versaflex Delivery Systems Inc.||Steerable catheter|
|US4770653 *||Jun 25, 1987||Sep 13, 1988||Medilase, Inc.||Laser angioplasty|
|US4822345 *||Mar 16, 1988||Apr 18, 1989||Danforth John W||Controllable flexibility catheter|
|US4826087 *||Feb 6, 1986||May 2, 1989||David Chinery||Manipulative device|
|US4827931 *||Jan 13, 1987||May 9, 1989||Longmore Donald B||Surgical catheters with suturing device and NMR opaque material|
|US4874371 *||Nov 5, 1987||Oct 17, 1989||Medilase, Inc.||Control handle|
|US4875897 *||Apr 6, 1988||Oct 24, 1989||Regents Of University Of California||Catheter assembly|
|US4909787 *||Aug 11, 1988||Mar 20, 1990||Danforth John W||Controllable flexibility catheter with eccentric stiffener|
|US4920980 *||Sep 14, 1987||May 1, 1990||Cordis Corporation||Catheter with controllable tip|
|US4921482 *||Jan 9, 1989||May 1, 1990||Hammerslag Julius G||Steerable angioplasty device|
|US4944740 *||Aug 18, 1988||Jul 31, 1990||Medtronic Versaflex, Inc.||Outer exchange catheter system|
|US4976688 *||Feb 3, 1989||Dec 11, 1990||Rosenblum Jeffrey L||Position-adjustable thoracic catheter|
|US4998916 *||Jan 4, 1990||Mar 12, 1991||Hammerslag Julius G||Steerable medical device|
|US5037391 *||Aug 1, 1990||Aug 6, 1991||Pilot Cardiovascular Systems, Inc.||Steerable angioplasty device|
|US5108368 *||Sep 17, 1990||Apr 28, 1992||Pilot Cardiovascular System, Inc.||Steerable medical device|
|US5123421 *||Jan 16, 1991||Jun 23, 1992||C. R. Bard, Inc.||Liquid activated steerable catheter guidewire|
|US5125895 *||Dec 19, 1988||Jun 30, 1992||Medtronic Versaflex, Inc.||Steerable catheter|
|US5167221 *||Mar 14, 1991||Dec 1, 1992||Kabushiki Kaisha Machida Seisakusho||Bending device|
|US5195968 *||Jul 17, 1992||Mar 23, 1993||Ingemar Lundquist||Catheter steering mechanism|
|US5199950 *||Aug 22, 1991||Apr 6, 1993||Willy Rusch Ag||Medical instrument|
|US5203772 *||Apr 8, 1992||Apr 20, 1993||Pilot Cardiovascular Systems, Inc.||Steerable medical device|
|US5254088 *||Dec 16, 1992||Oct 19, 1993||Ep Technologies, Inc.||Catheter steering mechanism|
|US5279559 *||Mar 6, 1992||Jan 18, 1994||Aai Corporation||Remote steering system for medical catheter|
|US5306245 *||Feb 23, 1993||Apr 26, 1994||Advanced Surgical Inc.||Articulating device|
|US5308324 *||Mar 17, 1993||May 3, 1994||Pilot Cardiovascular Systems, Inc.||Steerable medical device|
|US5318525 *||Apr 10, 1992||Jun 7, 1994||Medtronic Cardiorhythm||Steerable electrode catheter|
|US5318526 *||Sep 29, 1992||Jun 7, 1994||Neuro Navigational Corporation||Flexible endoscope with hypotube activating wire support|
|US5336182 *||Jul 30, 1993||Aug 9, 1994||Ep Technologies, Inc.||Catheter steering mechanism|
|US5342299 *||Jul 6, 1992||Aug 30, 1994||Catheter Imaging Systems||Steerable catheter|
|US5354266 *||Sep 30, 1993||Oct 11, 1994||Catheter Imaging Systems||Method of epidural surgery|
|US5358478 *||May 6, 1993||Oct 25, 1994||Ep Technologies, Inc.||Catheter steering assembly providing asymmetric left and right curve configurations|
|US5368564 *||Dec 23, 1992||Nov 29, 1994||Angeion Corporation||Steerable catheter|
|US5372587 *||Mar 15, 1993||Dec 13, 1994||Pilot Cariovascular Systems, Inc.||Steerable medical device|
|US5378234 *||May 14, 1993||Jan 3, 1995||Pilot Cardiovascular Systems, Inc.||Coil polymer composite|
|US5383852 *||Dec 4, 1992||Jan 24, 1995||C. R. Bard, Inc.||Catheter with independent proximal and distal control|
|US5395327 *||Jul 30, 1993||Mar 7, 1995||Ep Technologies, Inc.||Catheter steering mechanism|
|US5397304 *||Jun 29, 1993||Mar 14, 1995||Medtronic Cardiorhythm||Shapable handle for steerable electrode catheter|
|US5399164 *||Nov 2, 1992||Mar 21, 1995||Catheter Imaging Systems||Catheter having a multiple durometer|
|US5423807 *||Jan 24, 1994||Jun 13, 1995||Implemed, Inc.||Cryogenic mapping and ablation catheter|
|US5437636 *||Jul 22, 1994||Aug 1, 1995||Catheter Imaging Systems||Steerable catheter with fiberoptic scope inserting means|
|US5441483 *||Nov 8, 1993||Aug 15, 1995||Avitall; Boaz||Catheter deflection control|
|US5462527 *||Jun 29, 1993||Oct 31, 1995||C.R. Bard, Inc.||Actuator for use with steerable catheter|
|US5480382 *||Sep 2, 1994||Jan 2, 1996||Pilot Cardiovascular Systems, Inc.||Steerable medical device|
|US5489270 *||Jun 10, 1994||Feb 6, 1996||Cordis Corporation||Controlled flexible catheter|
|US5496269 *||Oct 11, 1994||Mar 5, 1996||Catheter Imaging Systems, Inc.||Method of epidural surgery|
|US5507725 *||Dec 22, 1993||Apr 16, 1996||Angeion Corporation||Steerable catheter|
|US5531686 *||Dec 23, 1994||Jul 2, 1996||Ep Technologies, Inc.||Catheter steering mechanism|
|US5531687 *||Dec 30, 1994||Jul 2, 1996||Catheter Imaging Systems||Steerable catheter|
|US5542924 *||Jan 13, 1995||Aug 6, 1996||Catheter Imaging Systems||Method of forming a catheter having a multiple durometer|
|US5549644 *||Feb 2, 1994||Aug 27, 1996||Vidamed, Inc.||Transurethral needle ablation device with cystoscope and method for treatment of the prostate|
|US5562619 *||Oct 19, 1993||Oct 8, 1996||Boston Scientific Corporation||Deflectable catheter|
|US5591141 *||Sep 15, 1995||Jan 7, 1997||Megadyne Medical Products, Inc.||Suction coagulator bending tool|
|US5611777 *||Aug 23, 1995||Mar 18, 1997||C.R. Bard, Inc.||Steerable electrode catheter|
|US5618294 *||Jul 21, 1995||Apr 8, 1997||Aust & Taylor Medical Corporation||Surgical instrument|
|US5624397 *||Sep 19, 1994||Apr 29, 1997||Snoke; Phillip J.||Catheter having a multiple durometer|
|US5666970 *||May 2, 1995||Sep 16, 1997||Heart Rhythm Technologies, Inc.||Locking mechanism for catheters|
|US5667488 *||Jan 25, 1995||Sep 16, 1997||Vidamed, Inc.||Transurethral needle ablation device and method for the treatment of the prostate|
|US5681280 *||May 2, 1995||Oct 28, 1997||Heart Rhythm Technologies, Inc.||Catheter control system|
|US5715817 *||Jun 7, 1995||Feb 10, 1998||C.R. Bard, Inc.||Bidirectional steering catheter|
|US5741320 *||May 2, 1995||Apr 21, 1998||Heart Rhythm Technologies, Inc.||Catheter control system having a pulley|
|US5762626 *||Aug 23, 1996||Jun 9, 1998||Vidamed, Inc.||Transurethral needle ablation device with cystoscope and method for treatment of the prostate|
|US5779699 *||Mar 29, 1996||Jul 14, 1998||Medtronic, Inc.||Slip resistant field focusing ablation catheter electrode|
|US5810790 *||Nov 19, 1996||Sep 22, 1998||Ebling; Wendell V.||Catheter with viewing system and port connector|
|US5820592 *||Jul 16, 1996||Oct 13, 1998||Hammerslag; Gary R.||Angiographic and/or guide catheter|
|US5846221 *||May 13, 1998||Dec 8, 1998||Catheter Imaging Systems, Inc.||Steerable catheter having disposable module and sterilizable handle and method of connecting same|
|US5851212 *||Jun 11, 1997||Dec 22, 1998||Endius Incorporated||Surgical instrument|
|US5853004 *||Jun 2, 1997||Dec 29, 1998||Goodman; Evan J.||Pharyngeal bulb airway|
|US5857996 *||Oct 22, 1997||Jan 12, 1999||Catheter Imaging Systems||Method of epidermal surgery|
|US5860953 *||Feb 9, 1996||Jan 19, 1999||Catheter Imaging Systems, Inc.||Steerable catheter having disposable module and sterilizable handle and method of connecting same|
|US5865800 *||Oct 8, 1996||Feb 2, 1999||Boston Scientific Corporation||Deflectable catheter|
|US5885288 *||Jun 11, 1997||Mar 23, 1999||Endius Incorporated||Surgical instrument|
|US5891088 *||Mar 6, 1997||Apr 6, 1999||Ep Technologies, Inc.||Catheter steering assembly providing asymmetric left and right curve configurations|
|US5899914 *||Jun 11, 1997||May 4, 1999||Endius Incorporated||Surgical instrument|
|US5935102 *||Oct 23, 1996||Aug 10, 1999||C. R. Bard||Steerable electrode catheter|
|US5938678 *||Jun 11, 1997||Aug 17, 1999||Endius Incorporated||Surgical instrument|
|US6007531 *||Jan 5, 1999||Dec 28, 1999||Catheter Imaging Systems, Inc.||Steerable catheter having disposable module and sterilizable handle and method of connecting same|
|US6010493 *||Apr 27, 1998||Jan 4, 2000||Catheter Imaging Systems||Method of epidural surgery|
|US6017322 *||Jan 5, 1999||Jan 25, 2000||Catheter Imaging Systems, Inc.||Steerable catheter having disposable module and sterilizable handle and method of connecting same|
|US6033378 *||Mar 27, 1997||Mar 7, 2000||Ep Technologies, Inc.||Catheter steering mechanism|
|US6066125 *||Nov 10, 1998||May 23, 2000||Cordis Webster, Inc.||Omni-directional steerable catheter|
|US6077287 *||May 28, 1999||Jun 20, 2000||Endius Incorporated||Surgical instrument|
|US6123699 *||Sep 5, 1997||Sep 26, 2000||Cordis Webster, Inc.||Omni-directional steerable catheter|
|US6146355 *||Jul 31, 1998||Nov 14, 2000||Myelotec, Inc.||Steerable catheter|
|US6165139 *||Jun 1, 1995||Dec 26, 2000||Fonar Corporation||Remotely steerable guide wire with external control wires|
|US6171277||Aug 7, 1998||Jan 9, 2001||Cordis Webster, Inc.||Bi-directional control handle for steerable catheter|
|US6183463||Aug 28, 1998||Feb 6, 2001||Cordis Webster, Inc.||Bidirectional steerable cathether with bidirectional control handle|
|US6198974||Sep 18, 1998||Mar 6, 2001||Cordis Webster, Inc.||Bi-directional steerable catheter|
|US6210407||Dec 3, 1998||Apr 3, 2001||Cordis Webster, Inc.||Bi-directional electrode catheter|
|US6213974||Dec 15, 1998||Apr 10, 2001||Visionary Biomedical, Inc.||Steerable catheter having segmented tip and one-piece inlet housing, and method of fabricating same|
|US6241702||Jun 9, 1998||Jun 5, 2001||Vidamed, Inc.||Radio frequency ablation device for treatment of the prostate|
|US6321749 *||Sep 27, 1999||Nov 27, 2001||Merlyn Associates Inc||Endotracheal tube with tip directional control and position preserving mechanism|
|US6464682||Jan 3, 2000||Oct 15, 2002||Catheter Imaging Systems, Inc.||Method of epidural surgery|
|US6470209||Jul 13, 1999||Oct 22, 2002||Catheter Imaging Systems, Inc.||System for enhancing visibility in the epidural space|
|US6482221||Oct 31, 2000||Nov 19, 2002||Counter Clockwise, Inc.||Manipulatable delivery catheter for occlusive devices (II)|
|US6500167||Nov 8, 1999||Dec 31, 2002||Biosense Webster, Inc.||Omni-directional steerable catheter|
|US6539942 *||Apr 19, 2001||Apr 1, 2003||Richard Schwartz||Endotracheal intubation device|
|US6544215||Oct 2, 1998||Apr 8, 2003||Scimed Life Systems, Inc.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US6553993||Nov 27, 2001||Apr 29, 2003||Merlyn Associates, Inc.||Endotracheal tube with tip directional control and position preserving mechanism|
|US6554793 *||Apr 7, 1999||Apr 29, 2003||Stm Medizintechnik Starnberg Gmbh||Flexible trocar with an upturning tube system|
|US6571131||Nov 10, 2000||May 27, 2003||Biosense Webster, Inc.||Deflectable catheter with modifiable handle|
|US6585717||Jun 15, 2000||Jul 1, 2003||Cryocath Technologies Inc.||Deflection structure|
|US6726700||Aug 21, 2000||Apr 27, 2004||Counter Clockwise, Inc.||Manipulatable delivery catheter for occlusive devices|
|US6761171||Apr 4, 2002||Jul 13, 2004||Andrew J. Toti||Endotracheal tube with tip directional control and position preserving mechanism|
|US6793667||Jun 27, 2002||Sep 21, 2004||Counter Clockwise, Inc.||Manipulatable delivery catheter for occlusive devices (II)|
|US6925323||Aug 12, 2002||Aug 2, 2005||Phillip Jack Snoke||System for enhancing visibility in the epidural space|
|US6976991||Mar 12, 2002||Dec 20, 2005||Stephen Hebert||Manipulatable delivery catheter for occlusive devices (LL)|
|US6991616||Jan 29, 2003||Jan 31, 2006||Boston Scientific Scimed, Inc.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US7008375||Mar 31, 2004||Mar 7, 2006||Surgical Solutions Llc||Articulating shaft|
|US7077823 *||Nov 19, 2003||Jul 18, 2006||Biosense Webster, Inc.||Bidirectional steerable catheter with slidable mated puller wires|
|US7137990||Sep 20, 2004||Nov 21, 2006||Micrus Endovascular Corporation||Manipulatable delivery catheter for occlusive devices (II)|
|US7241263||Sep 30, 2004||Jul 10, 2007||Scimed Life Systems, Inc.||Selectively rotatable shaft coupler|
|US7413543||Mar 29, 2004||Aug 19, 2008||Scimed Life Systems, Inc.||Endoscope with actively cooled illumination sources|
|US7479106||Sep 30, 2004||Jan 20, 2009||Boston Scientific Scimed, Inc.||Automated control of irrigation and aspiration in a single-use endoscope|
|US7553275||Aug 25, 2005||Jun 30, 2009||Surgical Solutions Llc||Medical device with articulating shaft|
|US7578786||Sep 30, 2004||Aug 25, 2009||Boston Scientific Scimed, Inc.||Video endoscope|
|US7591783||Sep 30, 2004||Sep 22, 2009||Boston Scientific Scimed, Inc.||Articulation joint for video endoscope|
|US7597661||May 11, 2006||Oct 6, 2009||Ethicon Endo-Surgery, Inc.||Medical instrument having a catheter and method for using a catheter|
|US7597662||May 8, 2006||Oct 6, 2009||Boston Scientific Scimed, Inc.||Multi-fluid delivery system|
|US7655004||Feb 15, 2007||Feb 2, 2010||Ethicon Endo-Surgery, Inc.||Electroporation ablation apparatus, system, and method|
|US7670284||Jun 8, 2007||Mar 2, 2010||Surgical Solutions Llc||Medical device with articulating shaft|
|US7695451||Apr 13, 2010||Boston Scientific Scimed, Inc.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US7731682||Oct 24, 2007||Jun 8, 2010||Boston Scientific Scimed, Inc.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US7758593||Jul 20, 2010||Ethicon Endo-Surgery, Inc.||Medical instrument handle and medical instrument having same|
|US7771416||Aug 10, 2010||Ethicon Endo-Surgery, Inc.||Control mechanism for flexible endoscopic device and method of use|
|US7815662||Mar 8, 2007||Oct 19, 2010||Ethicon Endo-Surgery, Inc.||Surgical suture anchors and deployment device|
|US7837620||Nov 23, 2010||Ethicon Endo-Surgery, Inc.||Medical tubular assembly|
|US7846107||Dec 7, 2010||Boston Scientific Scimed, Inc.||Endoscopic apparatus with integrated multiple biopsy device|
|US7892166||May 18, 2006||Feb 22, 2011||Ethicon Endo-Surgery, Inc.||Medical instrument including a catheter having a catheter stiffener and method for using|
|US7927327||Apr 19, 2011||Ethicon Endo-Surgery, Inc.||Medical instrument having an articulatable end effector|
|US7955255||Apr 20, 2006||Jun 7, 2011||Boston Scientific Scimed, Inc.||Imaging assembly with transparent distal cap|
|US7959642||May 16, 2006||Jun 14, 2011||Ethicon Endo-Surgery, Inc.||Medical instrument having a needle knife|
|US7967759||Jan 19, 2006||Jun 28, 2011||Boston Scientific Scimed, Inc.||Endoscopic system with integrated patient respiratory status indicator|
|US7972323||Apr 13, 2000||Jul 5, 2011||Boston Scientific Scimed, Inc.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US7985254||Jul 26, 2011||David Tolkowsky||Endobronchial fluid exhaler devices and methods for use thereof|
|US8029504||Oct 4, 2011||Ethicon Endo-Surgery, Inc.||Electroporation ablation apparatus, system, and method|
|US8037591||Feb 2, 2009||Oct 18, 2011||Ethicon Endo-Surgery, Inc.||Surgical scissors|
|US8046049||Feb 23, 2004||Oct 25, 2011||Biosense Webster, Inc.||Robotically guided catheter|
|US8052597||Nov 8, 2011||Boston Scientific Scimed, Inc.||Method for forming an endoscope articulation joint|
|US8070759||May 30, 2008||Dec 6, 2011||Ethicon Endo-Surgery, Inc.||Surgical fastening device|
|US8075572||Apr 26, 2007||Dec 13, 2011||Ethicon Endo-Surgery, Inc.||Surgical suturing apparatus|
|US8083671||Dec 27, 2011||Boston Scientific Scimed, Inc.||Fluid delivery system for use with an endoscope|
|US8097003||Jan 17, 2012||Boston Scientific Scimed, Inc.||Endoscopic apparatus with integrated variceal ligation device|
|US8100922||Apr 27, 2007||Jan 24, 2012||Ethicon Endo-Surgery, Inc.||Curved needle suturing tool|
|US8114072||May 30, 2008||Feb 14, 2012||Ethicon Endo-Surgery, Inc.||Electrical ablation device|
|US8114119||Sep 9, 2008||Feb 14, 2012||Ethicon Endo-Surgery, Inc.||Surgical grasping device|
|US8118732||Sep 30, 2004||Feb 21, 2012||Boston Scientific Scimed, Inc.||Force feedback control system for video endoscope|
|US8157834||Apr 17, 2012||Ethicon Endo-Surgery, Inc.||Rotational coupling device for surgical instrument with flexible actuators|
|US8172772||May 8, 2012||Ethicon Endo-Surgery, Inc.||Specimen retrieval device|
|US8196580||May 10, 2007||Jun 12, 2012||Yossi Gross||Implantable respiration therapy device|
|US8197400||Jun 12, 2012||Boston Scientific Scimed, Inc.||Selectively rotatable shaft coupler|
|US8199187||Jun 12, 2012||Boston Scientific Scimed, Inc.||Adapter for use with digital imaging medical device|
|US8202265||Jun 19, 2012||Boston Scientific Scimed, Inc.||Multiple lumen assembly for use in endoscopes or other medical devices|
|US8206343||Nov 3, 2006||Jun 26, 2012||Custom Medical Applications, Inc.||Reinforced catheter with articulated distal tip|
|US8206349||Jun 26, 2012||Medtronic Xomed, Inc.||Systems and methods for biofilm removal, including a biofilm removal endoscope for use therewith|
|US8211114||Apr 24, 2006||Jul 3, 2012||Ethicon Endo-Surgery, Inc.||Medical instrument having a medical snare|
|US8211125||Aug 15, 2008||Jul 3, 2012||Ethicon Endo-Surgery, Inc.||Sterile appliance delivery device for endoscopic procedures|
|US8214019||Sep 1, 2011||Jul 3, 2012||Biosense Webster, Inc.||Robotically guided catheter|
|US8241204||Aug 29, 2008||Aug 14, 2012||Ethicon Endo-Surgery, Inc.||Articulating end cap|
|US8252057||Jan 30, 2009||Aug 28, 2012||Ethicon Endo-Surgery, Inc.||Surgical access device|
|US8262563||Jul 14, 2008||Sep 11, 2012||Ethicon Endo-Surgery, Inc.||Endoscopic translumenal articulatable steerable overtube|
|US8262655||Nov 21, 2007||Sep 11, 2012||Ethicon Endo-Surgery, Inc.||Bipolar forceps|
|US8262680||Sep 11, 2012||Ethicon Endo-Surgery, Inc.||Anastomotic device|
|US8267951||Sep 18, 2012||Ncontact Surgical, Inc.||Dissecting cannula and methods of use thereof|
|US8268619||Jul 29, 2004||Sep 18, 2012||Universita Degli Studi Di Roma “La Sapienza”||Method for the isolation and expansion of cardiac stem cells from biopsy|
|US8287469||Oct 16, 2012||Ethicon Endo-Surgery, Inc.||Articulating surgical device and method of use|
|US8317806||Nov 27, 2012||Ethicon Endo-Surgery, Inc.||Endoscopic suturing tension controlling and indication devices|
|US8337394||Oct 1, 2008||Dec 25, 2012||Ethicon Endo-Surgery, Inc.||Overtube with expandable tip|
|US8348834||Jan 8, 2013||Ethicon Endo-Surgery, Inc.||Steerable surgical access devices and methods|
|US8353487||Dec 17, 2009||Jan 15, 2013||Ethicon Endo-Surgery, Inc.||User interface support devices for endoscopic surgical instruments|
|US8353860||Jan 15, 2013||Boston Scientific Scimed, Inc.||Device for obstruction removal with specific tip structure|
|US8353894 *||Dec 29, 2006||Jan 15, 2013||St. Jude Medical, Atrial Fibrillation Division, Inc.||Catheter platform and method of manufacture|
|US8357148||Jan 22, 2013||Boston Scientific Scimed, Inc.||Multi-functional endoscopic system for use in electrosurgical applications|
|US8361066||Jan 12, 2009||Jan 29, 2013||Ethicon Endo-Surgery, Inc.||Electrical ablation devices|
|US8361112||Jun 27, 2008||Jan 29, 2013||Ethicon Endo-Surgery, Inc.||Surgical suture arrangement|
|US8403926||Mar 26, 2013||Ethicon Endo-Surgery, Inc.||Manually articulating devices|
|US8409200||Apr 2, 2013||Ethicon Endo-Surgery, Inc.||Surgical grasping device|
|US8425408||Sep 17, 2009||Apr 23, 2013||Boston Scientific Scimed, Inc.||Articulation joint for video endoscope|
|US8425505||Apr 23, 2013||Ethicon Endo-Surgery, Inc.||Electroporation ablation apparatus, system, and method|
|US8435172||May 7, 2013||Boston Scientific Scimed, Inc.||Automated control of irrigation and aspiration in a single-use endoscope|
|US8449538||Jan 27, 2010||May 28, 2013||Ethicon Endo-Surgery, Inc.||Electroporation ablation apparatus, system, and method|
|US8475366||Aug 24, 2009||Jul 2, 2013||Boston Scientific Scimed, Inc.||Articulation joint for a medical device|
|US8480657||Oct 31, 2007||Jul 9, 2013||Ethicon Endo-Surgery, Inc.||Detachable distal overtube section and methods for forming a sealable opening in the wall of an organ|
|US8480689||Sep 2, 2008||Jul 9, 2013||Ethicon Endo-Surgery, Inc.||Suturing device|
|US8496574||Dec 17, 2009||Jul 30, 2013||Ethicon Endo-Surgery, Inc.||Selectively positionable camera for surgical guide tube assembly|
|US8506564||Dec 18, 2009||Aug 13, 2013||Ethicon Endo-Surgery, Inc.||Surgical instrument comprising an electrode|
|US8529563||Aug 25, 2008||Sep 10, 2013||Ethicon Endo-Surgery, Inc.||Electrical ablation devices|
|US8535219||Mar 31, 2010||Sep 17, 2013||Boston Scientific Scimed, Inc.||Fluid manifold for endoscope system|
|US8568410||Apr 25, 2008||Oct 29, 2013||Ethicon Endo-Surgery, Inc.||Electrical ablation surgical instruments|
|US8579897||Nov 21, 2007||Nov 12, 2013||Ethicon Endo-Surgery, Inc.||Bipolar forceps|
|US8585715||Dec 14, 2011||Nov 19, 2013||Boston Scientific Scimed, Inc.||Endoscopic apparatus with integrated variceal ligation device|
|US8608648||Nov 22, 2011||Dec 17, 2013||Boston Scientific Scimed, Inc.||Articulation joint|
|US8608652||Nov 5, 2009||Dec 17, 2013||Ethicon Endo-Surgery, Inc.||Vaginal entry surgical devices, kit, system, and method|
|US8615288||Jun 12, 2012||Dec 24, 2013||Biosense Webster, Inc.||Robotically guided catheter|
|US8622894||Dec 30, 2011||Jan 7, 2014||Boston Scientific Scimed, Inc.||Articulation joint|
|US8652150||May 30, 2008||Feb 18, 2014||Ethicon Endo-Surgery, Inc.||Multifunction surgical device|
|US8679003||May 30, 2008||Mar 25, 2014||Ethicon Endo-Surgery, Inc.||Surgical device and endoscope including same|
|US8734440||Mar 12, 2010||May 27, 2014||St. Jude Medical, Atrial Fibrillation Division, Inc.||Magnetically guided catheter|
|US8771260||May 30, 2008||Jul 8, 2014||Ethicon Endo-Surgery, Inc.||Actuating and articulating surgical device|
|US8772030||Sep 26, 2011||Jul 8, 2014||Universita Degli Studi Di Roma “La Sapienza”||Cardiac stem cells and methods for isolation of same|
|US8790301||Jun 13, 2012||Jul 29, 2014||Medtronic Xomed, Inc.||Systems and methods for biofilm removal, including a biofilm removal endoscope for use therewith|
|US8821376||Mar 12, 2008||Sep 2, 2014||David Tolkowsky||Devices and methods for performing medical procedures in tree-like luminal structures|
|US8828031||Jan 12, 2009||Sep 9, 2014||Ethicon Endo-Surgery, Inc.||Apparatus for forming an anastomosis|
|US8840560||Apr 4, 2007||Sep 23, 2014||Volcano Corporation||Ultrasound catheter and hand-held device for manipulating a transducer on the catheter's distal end|
|US8845522 *||Aug 14, 2008||Sep 30, 2014||Boston Scientific Scimed, Inc.||Medical instrument with a deflectable distal portion|
|US8846396||Aug 22, 2011||Sep 30, 2014||Universita Degli Studi Di Roma “La Sapienza”||Methods for the isolation of cardiac stem cells|
|US8858528||Apr 23, 2008||Oct 14, 2014||Ncontact Surgical, Inc.||Articulating cannula access device|
|US8870753||Jun 2, 2011||Oct 28, 2014||Boston Scientific Scimed, Inc.||Imaging assembly with transparent distal cap|
|US8882705||May 18, 2011||Nov 11, 2014||Biosense Webster, Inc.||Steerable catheter with in-plane deflection|
|US8888684||Mar 27, 2006||Nov 18, 2014||Boston Scientific Scimed, Inc.||Medical devices with local drug delivery capabilities|
|US8888792||Jul 14, 2008||Nov 18, 2014||Ethicon Endo-Surgery, Inc.||Tissue apposition clip application devices and methods|
|US8906035||Jun 4, 2008||Dec 9, 2014||Ethicon Endo-Surgery, Inc.||Endoscopic drop off bag|
|US8939897||Feb 4, 2011||Jan 27, 2015||Ethicon Endo-Surgery, Inc.||Methods for closing a gastrotomy|
|US8942530||Aug 27, 2012||Jan 27, 2015||San Marino Capital, Inc.||Endoscope connector method and apparatus|
|US8986199||Feb 17, 2012||Mar 24, 2015||Ethicon Endo-Surgery, Inc.||Apparatus and methods for cleaning the lens of an endoscope|
|US8992557||Aug 16, 2012||Mar 31, 2015||Ncontact Surgical, Inc.||Dissecting cannula and methods of use thereof|
|US9005198||Jan 29, 2010||Apr 14, 2015||Ethicon Endo-Surgery, Inc.||Surgical instrument comprising an electrode|
|US9010320||Mar 11, 2013||Apr 21, 2015||Furman Medical Llc||Manually articulated intubation stylet, intubation device and intubation method|
|US9011431||Sep 4, 2012||Apr 21, 2015||Ethicon Endo-Surgery, Inc.||Electrical ablation devices|
|US9028483||Dec 18, 2009||May 12, 2015||Ethicon Endo-Surgery, Inc.||Surgical instrument comprising an electrode|
|US9049987||Mar 15, 2012||Jun 9, 2015||Ethicon Endo-Surgery, Inc.||Hand held surgical device for manipulating an internal magnet assembly within a patient|
|US9078662||Jul 3, 2012||Jul 14, 2015||Ethicon Endo-Surgery, Inc.||Endoscopic cap electrode and method for using the same|
|US9095686||May 26, 2009||Aug 4, 2015||Universite De Strasbourg||Device for the controlled translational displacement of an elongate element|
|US9101733 *||Sep 29, 2009||Aug 11, 2015||Biosense Webster, Inc.||Catheter with biased planar deflection|
|US9138250||Apr 24, 2006||Sep 22, 2015||Ethicon Endo-Surgery, Inc.||Medical instrument handle and medical instrument having a handle|
|US9220526||Mar 20, 2012||Dec 29, 2015||Ethicon Endo-Surgery, Inc.||Rotational coupling device for surgical instrument with flexible actuators|
|US9226772||Jan 30, 2009||Jan 5, 2016||Ethicon Endo-Surgery, Inc.||Surgical device|
|US9233241||Jan 18, 2012||Jan 12, 2016||Ethicon Endo-Surgery, Inc.||Electrical ablation devices and methods|
|US9242088||Nov 21, 2014||Jan 26, 2016||Simon Fraser University||Apparatus and methods for assisted breathing by transvascular nerve stimulation|
|US9249392||Apr 28, 2011||Feb 2, 2016||Cedars-Sinai Medical Center||Methods and compositions for maintaining genomic stability in cultured stem cells|
|US9254169||Feb 28, 2011||Feb 9, 2016||Ethicon Endo-Surgery, Inc.||Electrical ablation devices and methods|
|US9277957||Aug 15, 2012||Mar 8, 2016||Ethicon Endo-Surgery, Inc.||Electrosurgical devices and methods|
|US9314620||Feb 28, 2011||Apr 19, 2016||Ethicon Endo-Surgery, Inc.||Electrical ablation devices and methods|
|US20020165571 *||Mar 12, 2002||Nov 7, 2002||Stephen Hebert||Manipulatable delivery catheter for occlusive devices (ll)|
|US20030135156 *||Jan 29, 2003||Jul 17, 2003||Bencini Robert F.||Steerable device for introducing diagnostic and therapeutic apparatus into the body|
|US20030208219 *||May 18, 2001||Nov 6, 2003||Aznoian Harold M.||Steerable biliary catheter|
|US20040106897 *||Nov 20, 2003||Jun 3, 2004||Thompson Russell B.||Assemblies for creating compound curves in distal catheter regions|
|US20040148029 *||Jan 13, 2004||Jul 29, 2004||Bianchi John R.||Open intervertebral spacer|
|US20040199051 *||Mar 31, 2004||Oct 7, 2004||Thomas Weisel||Articulating shaft|
|US20050038467 *||Sep 20, 2004||Feb 17, 2005||Counter Clockwise, Inc.||Manipulatable delivery catheter for occlusive devices (II)|
|US20050107737 *||Nov 19, 2003||May 19, 2005||Mcdaniel Benjamin D.||Bidirectional steerable catheter with slidable mated puller wires|
|US20050119614 *||Oct 18, 2004||Jun 2, 2005||Gerald Melsky||Irrigation and aspiration device|
|US20050203382 *||Feb 23, 2004||Sep 15, 2005||Assaf Govari||Robotically guided catheter|
|US20050256452 *||Jun 14, 2005||Nov 17, 2005||Demarchi Thomas||Steerable vascular sheath|
|US20060004329 *||Sep 6, 2005||Jan 5, 2006||Stephen Hebert||Manipulatable delivery catheter for occlusive devices (II)|
|US20070020758 *||Jul 29, 2004||Jan 25, 2007||Universita Degli Studi Di Roma "La Sapienza"||Method for the isolation and expansion of cardiac stem cells from biopsy|
|US20070185523 *||Feb 8, 2007||Aug 9, 2007||Stephen Hebert||Manipulatable delivery catheter for occlusive devices (II)|
|US20070249905 *||Apr 25, 2006||Oct 25, 2007||Nobis Rudolph H||Medical tubular assembly|
|US20070249908 *||Apr 24, 2006||Oct 25, 2007||Ifung Lu||Medical cannula and medical cannula system|
|US20070250012 *||Apr 24, 2006||Oct 25, 2007||Ifung Lu||Medical instrument having a medical needle-knife|
|US20070250070 *||Apr 24, 2006||Oct 25, 2007||Nobis Rudolph H||Medical instrument having a medical snare|
|US20070250111 *||Apr 25, 2006||Oct 25, 2007||Ifung Lu||Medical instrument having an articulatable end effector|
|US20070260264 *||May 4, 2006||Nov 8, 2007||Nobis Rudolph H||Medical instrument handle and medical instrument having same|
|US20070270649 *||May 18, 2006||Nov 22, 2007||Long Gary L||Medical instrument including a catheter having a catheter stiffener and method for using|
|US20070282187 *||May 11, 2006||Dec 6, 2007||Long Gary L||Medical instrument having a catheter and method for using a catheter|
|US20070282358 *||May 21, 2007||Dec 6, 2007||Stan Remiszewski||Steerable medical instrument|
|US20080009745 *||Apr 4, 2007||Jan 10, 2008||Volcano Corporation||Ultrasound catheter and hand-held device for manipulating a transducer on the catheter's distal end|
|US20080161761 *||Dec 29, 2006||Jul 3, 2008||Tegg Troy T||Catheter platform and method of manufacture|
|US20080188800 *||Oct 24, 2007||Aug 7, 2008||Bencini Robert F||Steerable Device For Introducing Diagnostic And Therapeutic Apparatus Into The Body|
|US20080214891 *||Mar 1, 2007||Sep 4, 2008||Slenker Dale E||Systems and methods for biofilm removal, including a biofilm removal endoscope for use therewith|
|US20080312506 *||Jun 14, 2007||Dec 18, 2008||Ethicon Endo-Surgery, Inc.||Control mechanism for flexible endoscopic device and method of use|
|US20090012422 *||Nov 8, 2005||Jan 8, 2009||Eduardo Marban||Bioptome|
|US20090043299 *||Nov 3, 2006||Feb 12, 2009||Racz N Sandor||Reinforced Catheter With Articulated Distal Tip|
|US20090069632 *||Aug 14, 2008||Mar 12, 2009||Boston Scientific Scimed, Inc.||Medical instrument with a deflectable distal portion|
|US20090107511 *||May 10, 2007||Apr 30, 2009||Yossi Gross||Implantable respiration therapy device|
|US20090177041 *||Jan 9, 2008||Jul 9, 2009||Ethicon Endo-Surgery, Inc.||Articulating surgical device and method of use|
|US20090270676 *||Oct 29, 2009||Ncontact Surgical, Inc.||Articulating cannula access device|
|US20090306476 *||Dec 8, 2008||Dec 10, 2009||Boston Scientific Scimed, Inc.||Automated control of irrigation and aspiration in a single-use endoscope|
|US20090306604 *||Dec 10, 2009||Darmos George P||Hybrid cannula/electrode medical device having protected wire passage|
|US20090312783 *||Jul 16, 2008||Dec 17, 2009||Ncontact Surgical, Inc.||Dissecting cannula and methods of use thereof|
|US20100041949 *||Mar 12, 2008||Feb 18, 2010||David Tolkowsky||Devices and methods for performing medical procedures in tree-like luminal structures|
|US20100093089 *||Nov 9, 2007||Apr 15, 2010||Eduardo Marban||Dedifferentiation of adult mammalian cardiomyocytes into cardiac stem cells|
|US20100111909 *||Jan 11, 2010||May 6, 2010||The Johns Hopkins University||Dedifferentiation of Adult Mammalian Cardiomyocytes into Cardiac Stem Cells|
|US20100112694 *||Jan 11, 2010||May 6, 2010||The Johns Hopkins University||Dedifferentiation of Adult Mammalian Cardiomyocytes into Cardiac Stem Cells|
|US20100160735 *||Dec 18, 2008||Jun 24, 2010||Ethicon Endo-Surgery, Inc.||Steerable surgical access devices and methods|
|US20100160736 *||Mar 1, 2010||Jun 24, 2010||Surgical Solutions Llc||Medical Device With Articulating Shaft|
|US20100174177 *||Jul 8, 2010||Kirk Wu||Magnetically guided catheter|
|US20110009699 *||Jan 13, 2011||Medtronic Xomed, Inc.||Methods for biofilm removal|
|US20110077498 *||Mar 31, 2011||Mcdaniel Benjamin D||Catheter with biased planar deflection|
|US20110184390 *||May 26, 2009||Jul 28, 2011||Universite De Strasbourg||Device for the controlled translational displacement of an elongate element|
|US20110218492 *||Sep 8, 2011||Mcdaniel Benjamin D||Steerable catheter with in-plane deflection|
|USD398986||Jan 16, 1996||Sep 29, 1998||Catheter Imaging Systems, Inc.||Handle interface for steerable catheter|
|USD405881||Jan 16, 1996||Feb 16, 1999||Catheter Imaging Systems, Inc.||Handle for steerable catheter|
|USRE38335||Mar 28, 2000||Nov 25, 2003||Endius Incorporated||Surgical instrument|
|USRE39152||Nov 6, 2000||Jun 27, 2006||Endius Incorporated||Surgical instrument|
|USRE42959||Nov 22, 2011||Abbott Cardiovascular Systems Inc.||Apparatus and methods for stimulating revascularization and/or tissue growth|
|USRE43300||Apr 18, 2002||Apr 3, 2012||Abbott Cardiovascular Systems Inc.||Apparatus having stabilization members for percutaneously performing surgery and methods of use|
|USRE45638 *||Aug 14, 2002||Aug 4, 2015||Abbott Cardiovascular Systems Inc.||Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and method of use|
|EP0077526A2 *||Oct 13, 1982||Apr 27, 1983||Olympus Optical Co., Ltd.||Endoscope system with an electric bending mechanism|
|EP0078017A2 *||Oct 20, 1982||May 4, 1983||Olympus Optical Co., Ltd.||Endoscope apparatus with motor-driven bending mechanism|
|EP0176865A1 *||Sep 17, 1985||Apr 9, 1986||Medtronic Versaflex, Inc.||Steerable soft-tip catheter and method of using same|
|EP0254701A1||Jul 20, 1987||Jan 27, 1988||Medtronic Versaflex, Inc.||Steerable catheter|
|EP0370785A1 *||Nov 22, 1989||May 30, 1990||Med Institute, Inc.||A catheter having durable and flexible segments|
|EP0684014A1 *||May 23, 1995||Nov 29, 1995||Gilbert M. Dr. Aust||Surgical instrument|
|EP0729730A1 *||Mar 1, 1995||Sep 4, 1996||Gilbert M. Dr. Aust||Surgical instrument|
|EP0737487A2 *||Apr 8, 1993||Oct 16, 1996||Cardiorhythm||Steerable electrode catheter|
|EP0904796A2 *||Sep 4, 1998||Mar 31, 1999||Cordis Webster, Inc.||Omni-directional steerable catheter|
|EP1197240A2 *||Mar 17, 1998||Apr 17, 2002||C.R. Bard, Inc.||Rotatable control mechanism for steerable catheter|
|EP1566150A2||Feb 22, 2005||Aug 24, 2005||Biosense Webster, Inc.||Robotically guided catheter|
|EP1915968A2||Feb 22, 2005||Apr 30, 2008||Biosense Webster, Inc.||Robotically guided catheter|
|EP2544749A1 *||Mar 10, 2011||Jan 16, 2013||St. Jude Medical Atrial Fibrillation Division Inc.||Magnetically guided catheter|
|EP2544749A4 *||Mar 10, 2011||Oct 2, 2013||St Jude Medical Atrial Fibrill||Magnetically guided catheter|
|EP2626033A2||Feb 22, 2005||Aug 14, 2013||Biosense Webster, Inc.||Robotically guided catheter|
|WO1983001893A1 *||Nov 30, 1982||Jun 9, 1983||Univ California||A catheter assembly|
|WO1987004080A2 *||Jan 13, 1987||Jul 16, 1987||Donald Bernard Longmore||Surgical catheters|
|WO1987004080A3 *||Jan 13, 1987||Aug 13, 1987||Donald Bernard Longmore||Surgical catheters|
|WO1990007355A1 *||Jan 5, 1990||Jul 12, 1990||Hammerslag Julius G||Steerable medical device|
|WO1991011213A1 *||Jan 31, 1991||Aug 8, 1991||Ep Technologies, Inc.||Catheter steering mechanism|
|WO1993020877A1 *||Apr 8, 1993||Oct 28, 1993||Cardiorhythm||Steerable electrode catheter|
|WO1993020878A1 *||Apr 8, 1993||Oct 28, 1993||Cardiorhythm||Shapable handle for steerable electrode catheter|
|WO1996022742A1 *||Jan 24, 1996||Aug 1, 1996||Vidamed, Inc.||Transurethral needle ablation device and method for the treatment of the prostate|
|WO1998041275A1 *||Mar 17, 1998||Sep 24, 1998||C.R. Bard, Inc.||Rotatable control mechanism for steerable catheter|
|WO2001008575A2||Jul 31, 2000||Feb 8, 2001||Cardiofocus, Inc.||Optical fiber basket device for cardiac photoablation|
|WO2001013812A1||Aug 25, 2000||Mar 1, 2001||Cardiofocus, Inc.||Maneuverable optical fiber device for cardiac photoablation|
|WO2007035297A2 *||Sep 11, 2006||Mar 29, 2007||John Schwartz||Endotracheal intubation device|
|WO2009153438A1 *||May 26, 2009||Dec 23, 2009||UNIVERSITE DE STRASBOURG (Etablissement Public National à Caractère Scientifique, Culturel et Professionnel)||Device for the controlled translational displacement of an elongate element|
|U.S. Classification||604/95.4, 600/146, 138/120, 600/585, 600/131, 273/DIG.500, 273/DIG.290, 273/DIG.400|
|International Classification||A61M25/01, A61B1/005|
|Cooperative Classification||Y10S273/29, Y10S273/05, A61M25/0136, A61M25/0147, Y10S273/04, A61B1/0052|
|European Classification||A61M25/01C10K, A61M25/01C10A, A61B1/005B4|