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Publication numberUS3474789 A
Publication typeGrant
Publication dateOct 28, 1969
Filing dateMay 8, 1967
Priority dateMay 8, 1967
Publication numberUS 3474789 A, US 3474789A, US-A-3474789, US3474789 A, US3474789A
InventorsSoto Ricardo Hurtado
Original AssigneeSoto Ricardo Hurtado
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Flexible ampoule
US 3474789 A
Abstract  available in
Images(1)
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Claims  available in
Description  (OCR text may contain errors)

ocr. 2s, 1969 R. H. SOT@ 3,474,789

FLEXI BLE AMPOULE Filed May 8, 1967 FIG. 2 .7

INVENTOR.- RICARDO HU RTADO SOTO ATT'YS ,SfaSiPatfO- 3,474,789 y I FLEXIBLE'AMPOULE i RicardoHurtado Soto, Aptdo. Aereo 9263, f Bogota, Colombia Continuation-in-part of application Ser. No. 405,551,

Oct. 21, 1964. This application May 8, 1967, Ser. Y No. 636,831

Int. Cl. A613' 1/06il365d 83/ 00 s ABSTRACT F THE DISCLOSURE A liexible ampoule for storing medicaments and the like. The ampoule comprises an outer envelope and an inner envelope, and an antioxidant or antiseptic material may be dispersed therebetween. The outer envelope is formed of a pair of relatively non-elastic films which are heat sealed together along their edges. The inner envelope includes a gusset along one edge thereof formed by folding the inner envelope along spaced parallel lines. The other edges of the inner envelope are heat se'aled together between the associated heat-sealed edges of the outer envelope.

RELATED APPLICATION This application is a continuation-in-part of my prior co-pending application entitled Liquid Container and Method, Ser. No. 405,551, filed Oct. 21, 1964, now abandoned.

BACKGROUND OF THE INVENTION This invention relates to a liquid-filled container, and nds particular utility in medicinal use. It is known that individual doses of Amedication to be injected are divided into small glass ampoules. However, handling, washing, filling and labeling of the ampoules are considered complicated and expensive operations. There is also a need for a container in which small quantities of medicine in powdered form, such as antibiotics, can be stored, diluted, and withdrawn without exposing the solution to air. Rubbercapped antibiotic flasks now in use have proved to be unsatisfactory for this use.

SUMMARY OF THE INVENTION The inventive ampoule stores a measured quantity of medicament and permits easy withdrawal of the medicament when it is to be administered. The heat sealed edge of the outer envelope which is adjacent the gusset of the inner envelope may be readily torn olf to expose the gusset. The sides of the gusset serve to guide a hypodermic syringe and facilitates perforation of the inner envelope by the syringe. After the medicament is withdrawn, the relatively inexpensive ampoule may be discarded.

DESCRIPTION OF THE DRAWING FIG. 1 is an elevational view of the inventive ampoule;

FIG. 2 is a view similar to FIG. 1 showing the contents of the ampoue being withdrawn;

FIG. 3 is a sectional view taken along the line 3--3 0f FIG. l; and

FIG. 4 is a fragmentary sectional view showing the contents ofthe ampoule being withdrawn.

DESCRIPTION OF THE PREFERRED EMBODIMENT Referring now to FIGS. 1 and 3, the numeral 10 designates -generally the inventive ampoule, which may advantageously be formed according to the method described in my co-pending application entitled Method of Forming Flexible Ampoules, Ser. No. 636,830, filed May 8, 1967.

3,474,789 A PatentedvOct-UZS, 1969 IICC , Ampoule is seen to be generally rectangular in shape t Ul Derivatives of the phenol group such as hexylresorcin hav been found particularly suitable.

Outer envelope 11 is advantageouslyl formed of a pair of films 14 and 15 of a relatively non-elastic material which is relatively impervious to oxygen and moisture such as ethyl vinyl acetate, polyvinylidene chloride (saran), or the like. It is desirable that at least one of the films 14 or 15 be transparent in order to permit visual observation of the contents of the ampoule. However, one of the ilms may be of metallic foil or other opaque material which provides better protection for the inner envelope. The edges of the lms 14 and 15 are heat sealed together as at 16, 17, 18, and 9.

Inner envelope 13, which is preferably made of an elastic thermo-plastic material such as polyethylene, is also generally rectangular in shape and is approximately co-extensive with the outer envelope, One end of the inner envelope is seen to be provided with a gusset 20 which is formed by folding the inner envelope along spaced parallel lines as at 21, 22, and 23. The gusset-equipped edge of the inner envelope terminates short of the sealed edge 19 of the outer envelope, and the sides of the gusset formed by fold lines 21 and 23 are preferably of unequal length. The edge of the inner envelope opposite the gusset is heat sealed between the associated edge of the outer envelope by heat seal 17, and the edges of the inner envelope extending transversely of the gusset are also heat sealed between the associated edges of the outer envelope by seals 16 and 18. The inner envelope thereby provides a liquid-tight pocket 24 in which medicaments may be stored.

When it is desired to withdraw the contents of the ampoule, the nurse or physician tears the outer envelope along the seal 19, thereby exposing the gusset 20 of the inner envelope. A needle 25 of a hypodermic syringe 26 may then perforate the inner envelope along the fold 22 of the gusset. The gusset guides the syringe and facilitates perforation of the inner envelope. The unequal sides of the gusset facilitate insertion of the syringe between the gusset sides, and the shorter gusset side providing by the fold 21 may be more readily observable by imprinting thereon a line 27.

When the lm 12 is an antiseptic, the gusset 20 becomes coated with the antiseptic and the needle of the syringe is lubricated with the antiseptic as it passes through the gusset, thereby preserving the aseptic qualities of the arnpoule contents.

The inventive ampoule permits ready insertion of the syringe when it is iilled with either a liquid or a powdered medicament. The ampoule may be used to store a small quantity of medicine in a powdered form, such as an antibiotic. The medicine can be diluted in the ampoule by injection of a solvent through the syringe, and when the powder is dissolved, the solution can be aspirated by the syringe. The ampoule thereby allows antibiotics to be prepared for use without the introduction of air, which cannot be done with antibiotic asks provided with rubber caps currently being used.

While in the foregoing specifications, detailed description of the preferred embodiment was set down for the purpose of explanation, many variations of the details herein given may be made by those skilled in the art Without departing from the spirit and scope of the invention.

I claim:

1. A flexible container of generally rectangular shape comprising an outer envelope and an inner envelope, said outer envelope formed by a pair of films, said films being heat sealed along the edges thereof, said inner envelope being disposed within the outer envelope and being folded on itself along spaced parallel lines to develop a gusset along one edge, the other edges of said inner envelope being heat sealed between associated edges of said films.

2. The container of claim 1 in which an antioxidant is dispersed between said inner and outer envelopes.

3. The container of claim 1 in which an antiseptic is dispersed between said inner and outer envelopes.

4. The container of claim 1 in which said gusset is developed by three reverse folds of said inner envelope to form a pair of gusset sides, said sides being of unequal length.

. .14v Y 5. The container of claim 1 in which said films are relatively non-elastic.

References Cited 5 UNITED STATES PATENTS 2,687,130 8/1954 Cohen 12S-272 2,676,212 12/1954 Dunmre .12S-216 2,737,339 3/1956 Doyle 229.-55 2,760,630 8/1956 Lasko.

10 3,255,872 6/1966 Long etal.

RICHARD A. GAUDET, Primary Examiner M. F. MAJESTIC, Assistant Examiner l5 U.S. Cl. X.R.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2676212 *Aug 20, 1948Apr 20, 1954Clevite CorpMagnetic recording and reproducing
US2687130 *Jan 13, 1950Aug 24, 1954Cohen Milton JMedicament and container therefor
US2737339 *Oct 2, 1951Mar 6, 1956Arkell Safety Bag CoMultiply bags
US2760630 *Dec 8, 1954Aug 28, 1956Sterling Drug IncFoil covered ampoule
US3255872 *Nov 17, 1959Jun 14, 1966Continental Can CoTwo compartment package
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3991912 *Jan 23, 1975Nov 16, 1976Ricardo Hurtado SotoFlexible package with counter-pressure dispenser
US4078699 *Jun 16, 1976Mar 14, 1978Steriflex Packaging Co.Flexible package with fluid-pressure sealing dispenser
US4089415 *Jul 14, 1976May 16, 1978Laib Jakob CAmpule
US4263910 *Apr 21, 1980Apr 28, 1981Eli Lilly And CompanyImplantate package, system and method
US4553971 *Mar 23, 1983Nov 19, 1985Metal Box P.L.C.Pouch-like bags for containing liquids
US5006117 *Jan 17, 1989Apr 9, 1991Instruments Medecine VeterinaireContainer for biological liquids
US5084042 *Jun 29, 1990Jan 28, 1992Mcgaw, Inc.Medical solution container outlet port with improved pierceable diaphragm
US5121996 *Nov 4, 1988Jun 16, 1992Drg Flexpak LimitedFluid containers and ports therefor
US5251982 *Jul 6, 1989Oct 12, 1993Ab Tetra PakDischarging device for a packaging container
US6077208 *Jul 27, 1998Jun 20, 2000The Coca-Cola CompanyStable flexible pouch and method for making the pouch
US6164825 *Dec 4, 1997Dec 26, 2000The Coca-Cola CompanyStable, flexible, easy open pouch
US6270255 *Apr 18, 1997Aug 7, 2001Kraft Foods, Inc.Opening system for beverage container
US8297841 *Feb 5, 2010Oct 30, 2012Sonoco Development, Inc.Tubular package
US8772034 *Oct 24, 2011Jul 8, 2014Roche Diagnostics Operations, Inc.Control solution packets and methods for calibrating bodily fluid sampling devices
US20110195209 *Feb 5, 2010Aug 11, 2011Sonoco Development, Inc.Tubular package
US20120041341 *Oct 24, 2011Feb 16, 2012Juergen Rasch-MengesControl solution packets and methods for calibrating bodily fluid sampling devices
WO1983002226A1 *Dec 22, 1982Jul 7, 1983Hardy, Peter, DerekPouch-like bags for containing liquids
Classifications
U.S. Classification604/408, 229/202, 604/415, 383/203, 383/200, 383/109, 383/120, 206/484.2
International ClassificationA61J1/06
Cooperative ClassificationA61J1/06
European ClassificationA61J1/06
Legal Events
DateCodeEventDescription
Sep 6, 1985AS02Assignment of assignor's interest
Owner name: CYCLO-PROCESS R&D
Owner name: HURTADO, RICARDO M.
Effective date: 19850825
Sep 6, 1985ASAssignment
Owner name: HURTADO, RICARDO M.
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:CYCLO-PROCESS R&D;REEL/FRAME:004451/0627
Effective date: 19850825
Feb 4, 1985AS02Assignment of assignor's interest
Owner name: CYCLO-PROCESS R&D, CORP. OF FL.
Effective date: 19850111
Owner name: STERIFLEX PACKAGING COMPANY
Feb 4, 1985ASAssignment
Owner name: CYCLO-PROCESS R&D, CORP. OF FL.
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:STERIFLEX PACKAGING COMPANY;REEL/FRAME:004363/0178
Effective date: 19850111