|Publication number||US3490452 A|
|Publication date||Jan 20, 1970|
|Filing date||Jun 20, 1967|
|Priority date||Jun 20, 1967|
|Publication number||US 3490452 A, US 3490452A, US-A-3490452, US3490452 A, US3490452A|
|Inventors||Greenfield Samuel L|
|Original Assignee||Greenfield Samuel L|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (50), Classifications (11)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Jan. 20, 1970 s. 1.. GREENFIELD 3,490,452
THERAPEUTIC FACE MASK Filed June 20, 1967 4 Sheets-Sheet 1 INVENTOR SAMUEL L. GREENFIELD ATTORNEY.
Jan. 20, 1970 s. 1.. GREENFIELD ,4
THERAPEUTIC FACE MASK Filed June 20, 1967 4 Sheets-Sheet 2 Fl G. 2
2 l 39 awax 2O b INVENTOR. SAMUEL L. GREENFIELD BY.
Jan. 20, 1970 s. 1.. G-REENFIELD 3, 9
THERAPEUTIC .FACE MASK Filed June 20, 1967 4 Sheets-Sheet 4 INVENTOR SAMUEL L. GREENFIELD ATTORNEY.
United States Patent 3,490,452 THERAPEUTIC FACE MASK Samuel L. Greenfield, Stevenson Terrace, 6201 N. 10th St, Philadelphia, Pa. 19126 Filed June 20, 1967, Ser. No. 647,496 Int. Cl. A61j 7/00; A61m 15/00, 16/00 US. Cl. 128-196 Claims ABSTRACT OF THE DISCLOSURE The therapeutic face mask is formed from two separable parts. One part consists of a face mask portion which is provided at its forward end with an integral receiving chamber having an open top and also with a side inlet port adapted to be connected to a suitable oxygen supply source. The second part of the face mask consists of an elongated mouth tube which is positioned Within the face mask and extends horizontally therein. One end of the mouth tube terminates in a cylindrical nebulizer chamber which is received and retained in the receiving chamber in nested relation. The nebulizer chamber is provided with an inlet port which is adapted to communicate with an oxygen supply source. A removable adapter head is provided which can be positioned in the nebulizer chamber. A conventional aerosol cartridge containing therapeutic agents is adapted to be received in the adapter head for supplying a controlled stream of nebulized therapeutic agents to the nebulizer chamber. The oxygen stream and nebulized stream supplied by the cartridge are commingled in the nebulizer chamber and are then fed into the mouth tube and directly into the patients mouth.
BACKGROUND OF THE INVENTION Field of the invention Nebulization therapy is concerned with delivering a dose of medication in the treatment of patients suffering from chronic bronchitis, emphysema, asthma and other diseases. In such cases the pulmonary airways are constricted, congested, or edematous, and obstructed with thick secretions. It is therefore necessary to achieve effective bronchodilation and mucosol decongestion and in some cases to administer antibiotics, steroids, liquefying agents, etc. Deposition of the necessary agents is accomplished by delivery of medication by nebulization; that is, by administering the medication in droplets suspended in air or other gases which are deposited in the respiratory tract upon inhalation of the nebulized medication.
Description of prior art It has been found that the droplets in nebulized streams tend to coalesce when the stream changes direction of flow or encounters a bafiiing action; coalescence of droplets also occurs when turbulence is increased in the nebulized stream. In recent years cartridge-type bronchodilator aerosol generators have become available. A selfcontained propellant (Freon, etc.) delivers a metered stream of bronchodilator particles when a plunger is depressed. These metered dose cartridges are very convenient for administering bronchodilator or bronchodilatordecongestant drugs, especially in ambulatory patients. Their main disadvantage is that production of mist occurs over too short a time to allow full utilization of slow, deep inhalation. Furthermore, losses of the nebulized drugs occur when such cartridge generators are used on account of rain-out or coalescence of the particles.
SUMMARY OF THE INVENTION The present invention provides a face mask which is constructed to retain a cartridge-type aersol generator conice taining the prescribed medicinal agents so that the medication can be self-administered by the patient by manually depressing the plunger provided in such cartridges. The nebulized stream of medication is administered directly into the mouth and is inhaled by the patient orally so that treatment of the entire respiratory tract and depths of the lungs is accomplished. The present face mask also provides means for supplying a stream of oxygen or other gas to the face mask and simultaneously supplying a nebulized stream of medication which are commingled and inhaled by the patient to ensure that the entire respiratory tract and lungs are treated with the medication and to maintain the medication droplets in the optimum droplet size for deposition in the respiratory tract. The present invention also ensures that any rain-out of the medication is reduced to a minimum and if any coalescence of the drops occurs, the secondary stream of oxygen or other gas fed to the mask will nebulize the coalesced drops.
The mask is designed to serve a dual purpose-for acute emergency situations and for daily or as needed therapy.
The essential features of its construction permit a controlled fiow of oxygen into the mask and the use of nebulizer mouthpiece built into the mask as one unit. The nebulizer is designed for the use of cartridge-type aerosol generators containing the appropriate medication and prescribed by the patients physician. This is inhaled into the lungs through a mouthpiece.
While primarily designed to be adapted to a small portable source of medicinal oxygen, it can be connected to any other oxygen intake including piped in oxygen in hospital rooms.
The oxygen when released flows directly through the nebulizer mouthpiece portion and can be used independently or simultaneously with the flow of nebulized medication. Likewise, the aerosol medication can be used in dependently.
Thus the oxygen can be used separately for emergency purposes or when combined with the medicinal mist cause it to break down into finer particles resulting in deeper penetration into the air sacs (alveoli) of the lungs with greater therapeutic effect. The patient can obtain the initial beneficial effects of his medication and then immediately follow with some inhalations of oxygen for additional comfort.
While most of the aerosol cartridge-type medical inhalants to be used in this adapter will be of the decongestant, bronchodilating type, to correct the interference with the normal movement of air in and out of the lungs, such as in asthma, emphysema, chronic bronchitis, other types of aerosol medication have been or will be developed which can be used in this unitfor instance one recently released for treatment of migraine headaches.
According to the present invention the face mask is constructed to enclose the mouth and nose portions of the face of a patient for medical treatment of his respiratory system or other system for which aerosol medication by inhalation is available. The mask is preferably formed of two separable parts. These parts can be assembled and easily disassembled for cleaning or sterilizing the parts after use. One part consists of a face receiving chamber which is open at the top. The other part consists of a removable mouth tube which is open at its front end to be receivable within the mouth of a patient and the other end terminates in a cylindrically shaped nebulizer chamber. The mouth tube is adapted to be positioned Within the face mask portion so as to extend lengthwise therein with the nebulizer chamber being positioned within the receiving chamber of the face mask portion in nested relation. These two chambers are generally complemental in shape. The mouth tube and face mask portion if desired can be formed in an integral unit without being separable.
The nebulizing chamber has an open top for receiving a removable adapter which receives and retains an aerosol cartridge filled with a suitable aerosol therapeutic drug composition which is ejected under pressure by actuating a valve provided in the aerosol cartridge. The nebulizer chamber is also provided with an inlet port through which a stream of oxygen or other gas under suitable pressure is supplied. The stream of oxygen or other gas and aerosol drug composition are mixed in the nebulizer chamber and flow through the mouth tube extending forwardly within the face mask. The open end of the mouth tube is adapted to be received in the mouth of the patient and to be sealed by his lips. The stream of nebulized therapeutic composition is thus fed directly into the mouth of the patient in completely nebulized condition for inhalation by the patient. The present mask construction facilitates the administration of combined medicinal oxygen and selected drugs such as bronchodilating, vasoconstricting, mucolytic and other drugs for treating the respiratory system by inhalation, or other systems when such medication is available.
BRIEF DESCRIPTION OF THE DRAWINGS bled face mask,
FIGURE 5 is an elevational rear view of the assembled face mask,
FIGURE 6 is an enlarged vertical sectional view showing a modified construction of the cartridge adapter head, and
FIGURE 7 is a perspective view of a modified construction of a disassembled face mask showing the separate components thereof.
DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring to the drawings, FIGURE 1 shows an illustrative embodiment of my invention. The face mask is preferably formed from a normally rigid plastic material, such as acrylic resin, polypropylene and the like. The face portion is designated generally by numeral 10. The mouth tube is designated generally by numeral 30. The cartridge adapter is designated generally by numeral 50. The aerosol cartridge is designated generally by numeral 70. These parts are suitably dimensioned so that they can be readily assembled into an operable unit, as shown in FIGURE 2, and connected to a suitable source of oxygen, designated in general by numeral 100. These parts are preferably individually separable and can be readily assembled manually for use. The parts are suitably proportioned so that they interfit closely to avoid gas leakage and the respective passageways and parts provided therein are precisely aligned. The separate parts are assembled by first inserting mouth tube 30 Within the face mask portion 10 so that it extends lengthwise therein with the aerosol chamber 32a being positioned within the receiving chamber 32 in nested relation as shown in FIGURES 2 and 3. The cartridge adapter 50 is then positioned within the open top of the aerosol chamber 32a in the position shown in FIGURE 2. The aerosol cartridge is shown in FIGURE 2 in elevated position prior to its insertion in the adapter 50 for the sake of clarity. The cartridge 70 contains a selected pressurized inhalation aerosol therapeutic composition suitable for treatment of a specific pulmonary condition or other disease of a patient. The cartridge 70 is preferably provided with a valve housing 71 terminating in a neck portion 72 and hollow plunger 73. The specific valve gonstruction is disclosed in Patent 2. 1. 10. 0st. 1 195.5, whi h d sp nses measured amounts of the aerosol composition stored in the cartridge. A suitable desired therapeutic inhalation composition is stored in the cartridge 70 which is suitably pressurized with non-toxic volatile lower alkane conventional propellants, such as dichloro difluoromethane, 1,2- dichloro-1,2,2-tetrafluoroethane, their mixtures, and the like. When the assembled mask is connected to the oxygen cylinder 100, as shown in FIGURE 2, and the cartridge 70 is positioned in the cartridge adapter, upon manually tilting the front end of the mask downwardly from its horizontal position as shown in FIGURE 2, plunger pin 101 of the oxygen cylinder will be depressed and pressurized oxygen will flow through inlet port 21 and port 22 in the stem 39 of the mouth tube 30, into the aerosol chamber 32a as indicated by arrow a where the oxygen stream will commingle with the aerosol therapeutic stream ejected, through port 57 of the cartridge adapter when cartridge 70 is manually depressed so as to actuate plunger 73. The combined nebulized stream then flows through the mouth tube as indicated by the arrows b into the mouth of the patient.
The face mask portion 10 is suitably dimensioned and contoured to receive the nose and mouth portions of the patient. The face mask is generally conical in shape and may be provided in different sizes for use by adults, children or infants. The open end of the face mask is provided with an outwardly beaded or rolled rim 14 to facilitate snug sealing contact with the face portions of the patient. The side wall portions 15 of the face mask are formed with integral elevated portions 11 which are provided with a plurality of spaced openings 12 to permit escape of excess gas pressure or air expelled by the patient when in position on the patients face.
The face mask portion is provided at its upper front portion with a flat vertical wall 16 having integral therewith a projecting key portion 17. The lower portion of face mask is connected to a receiving chamber 32 and communicates therewith (see FIGURE 1). The chamber 32 is open at the top 38 and closed at the bottom 13. The Opposed side walls and bottom wall 13 of the receiving chamber are connected to the sides and bottom wall of the mask portion and form continuous extensions thereof. The side walls 13' of the receiving chamber merge in a forward rounded end wall which is provided with a sleeve portion 34 having a passageway 33 for receiving stem 39 of the mouth tube 30 (see FIGURE 2).
The stem 39 is provided with an internal channel or port 22 which extends longitudinally thereof, as shown in FIGURES 2 and 3. The channel 22 communicates with opposed inlet ports 21 provided in stem 39 and which extend at right angles thereto, as shown in FIGURE 3. Channel 22 communicates with chamber 32a, as shown in FIGURE 2. The outer end of stem 39 is provided with a hole 20 adapted to receive a pivot pin 20, as shown in FIGURE 2, and which is carried by the head portion of oxygen cylinder 100. Valve pin 101 in the head portion 105 controls the flow of oxygen stored under pressure in cylinder 100. The details of this valve construction are disclosed in Patent 3,186,407, June 1, 1965. When the entire face mask assembly is manually tilted downwardly on the pivot pin 20' from its horizontal position shown in FIGURE 2, valve pin 101 will be depressed by virtue of the leverage applied by stem 39 against it. The head portion 105 is enclosed by a flexible rubber cover 104 which also embraces and seals sleeve 34 and thus prevents escape of oxygen.
The cylindrical cartridge adaptor 50 is preferably made of a suitable plastic material and is provided with an external longitudinal groove 58, as shown in FIGURES 1 and 3, for receiving the key portion 17. A slightly modified construction of the adapter is shown in FIGURE 6. In both constructions the adapter is provided with an internal longitudinal bore 56a which communicates with outlet port 57 positioned at right angles thereto. This onst uction is shown in FIGURE 6.
Mouth tube 30 is provided with a beaded edge 31 at its outer open end which is adapted to be contacted and sealed by the lip portions of the patient when in use. The other end 37 of the mouth tube terminates and communicates with a cylindrical nebulizer chamber 32a which is provided with an inlet port 33 in sleeve 34. The nebulizer chamber 32a is proportioned and shaped so as to be receivable and nestable within the chamber 32 as shown in FIGURE 2 when the mouth tube 30 is positioned longitudinally within the mask. The lower wall portion of the nebulizer chamber 32a is provided with circular area defined by a circular protrusion or ridge 36 integral with the lower Wall of the chamber, as shown in FIGURES 1 and 2. This circular ridge serves to locate and position the stem 56 of adapter 50, as shown in FIGURE 2, when the adapter is positioned within the nebulizer chamber 32a. The vertically extending groove 58 in adapter 50 is positioned in the side wall of the adapter so that the exit port 57 is aligned with-the inlet port 33 of the mouth tube.
The adapter 50 is suitably dimensioned to receive the cylindrical valve housing 71 of cartridge 70. The collar portion terminates in neckportion 72 which retains the hollow valve-actuating plunger 73. When the cartridge 70 is positioned in adapter 50 the hollow plunger 73 will extend into the longitudinal port 102 provided in adapter 50 (see FIGURE 6). When the cartridge 70 is manually depressed the plunger 73 will move inwardly of the valve housing provided in the cartridge 70 and actuate the valve to permit a measure amount of aerosol material to be ejected through the bore 103 of the plunger 73. The aerosol stream will then flow downwardly through the bore 103 in adapter 50 and then laterally through orifice 57 into the aerosol chamber 32a provided at the inner end of the mouth tube 30 as previously described. The aerosol stream supplied from cartridge 70 will commingle with a stream of oxygen which is supplied to the aerosol chamber through inlet port 33 as previously described. The commingled oxygen and aerosol stream will flow in a straight unimpeded path directly into the inlet port 37 of the mouth tube 30 in a straight unimpeded path as shown by arrows b in FIGURE 2 and then directly into the mouth of the patient.
It is to be understood that the invention is not restricted to the specific embodiment previously described and that changes and modifications may be made which embody the essential features of the invention. The adapter for receiving the aerosol cartridge may obviously be replaced by other modified constructions for receiving other types of aerosol cartridges. For example, FIGURE 6 illustrates a modified construction of the cartridge adapter which is designated by numeral 50A. It is similar to the adapter 50 shown in FIGURE 1 except that it is provided with a flange 90 adapted to seat on the shoulder 23 of the inner end of the mouth tube 30. The foot portion 56 of the adapter seats in the area defined by circular ridge 36 as in the construction shown in FIGURE 2. The aerosol stream flows through the bore 103 of hollow plunger 73 of the aerosol cartridge 70 into the vertical passageway 56a in the adapter and then laterally through exit port 57 which in turn communicates with the inlet 37 of the mouth tube 30.
FIGURE 7 illustrates a modified face mask construction. The face mask 10 has the same general construction as the mask shown in FIGURE 1 except that sleeve 34 is not provided with a stem 39 as in FIGURE 1. Mouth tube 60 is similar to the mouth tube in FIGURE 1 except that the sleeve 34 is provided with a connector stem 64 having a bore 66 extending therethrough and communieating with nebulizing chamber 62. Chamber 62 has a port 67 which communicates with mouth tube 60. The mouth tube 60 is adapted to be inserted within the face mask portion 10 so that nebulizing chamber 62 is positioned and nested within receptacle portion 32. Connector 6 stem 64 will then extend externally through the opening 3 of sleeve 34 in the same relation as stem 39 extends from chamber 32 as shown in FIGURE 1. Stem 64 is provided with a grooved surface 65 for frictionally retaining the end of hose 81 which is connected to a suitable source of oxygen, such as a conventional oxygen cylinder or to a piped-in oxygen system used in hospitals. In event a cartridge 70 is not required for supplying medication to mask 10 and only oxygen or other gas is to be supplied from cylinder 100, the open end 38 of receiving chamber 32 can be closed by a closure or cover 80. In the event it is desired to administer oxygen and an aerosol inhalant composition, the closure is remved and the cartridge adapter 50 is inserted in the receptacle 32. An aerosol cartridge is then positioned in the adapter to supply an aerosol stream of inhalant composition as desired.
The present invention provides convenient means for administering oxygen alone or admixed with nebulized drugs for inhalation therapy. Mist is always changed as it passes through conventional equipment; large droplets are selectively removed by any bend or change in direction in flow. At the same time, turbulence increases the coalescence of smaller droplets. In the present mask construction the aerosol stream generated from the cartridge which issues from the -degree bend through orifice 57 is promptly diluted and evaporated to smaller droplet size as the stream enters the nebulizer chamber 32a and commingles with the oxygen stream entering the nebulizer chamber 32a through inlet 33. Any rain-out of the aerosol stream will be promptly evaporated to smaller droplets in the nebulizer chamber as well as in the month tube. The interior side wall of the nebulizer chamber 32a is preferably cylindrical in shape and it has a smooth and continuous surface which facilitates complete mixing of the oxygen stream and aerosol stream of medicament agents fed into the nebulizer chamber without turbulence. Such construction ensures minimum rainout of the aerosol stream and facilitates the evaporation of the droplets so as to produce the smallest possible droplet size of the therapeutic agents for inhalation by the patient. Penetration of the medication into the bronchi of the patient is thus achieved by making delivery of a very fine aerosol and deposit of the medication agent throughout the depths of the lung. The present construction assures more penetration of the medication through the mouth into the alveoli by achieving complete evaporation and reduction of particle size of the droplets before they are inhaled.
It is to be understood that modifications and changes may be made in the specific details of the embodiments of the invention previously described and that such modifications embodying the essential features of this invention are intended to be included within the scope of the appended claims.
, I claim:
1. A face mask for administering therapeutic agents to a patient for inhalation in nebulized condition which comprises a mask portion having an open end, side walls, a bottom wall, and a vertically extending forward end wall, terminating short of the bottom wall, the open end of the mask portion being dimensioned and contoured to receive the nose and mouth portions of the patient and contact the adjacent face portions in sealing relation, :1 receiving chamber extending forwardly of the lower portion of the said forward vertical end wall of the mask portion, said receiving chamber consisting of opposed side walls, a bottom wall and top wall, the said opposed side walls of the receiving chamber being aligned with the adjacent side walls of the mask portion and the said bottom wall of the receiving chamber being aligned with the adjacent bottom wall of the mask portion to provide an unobstructed passageway from the receiving chamber into the mask portion, the said top wall of the receiving chamber being provided with an opening retaining nebulizer means to supply a stream of nebulized therapeutic agents, a mouth tube positioned and extending horizontally within the said mask portion, the open end of said mouth tube being dimensioned to be receivable with in the mouth of the patient and embracingly sealed by the lips of the patient, the forward end of the mouth tube being integrally connected to a nebulizer chamber, said nebulizer chamber having an open top receiving therethrough said means to supply a stream of nebulized therapeutic agents, said nebulizer chamber being generally complemental in shape with the receiving chamberand positioned in nested relation within said receiving cham her, and Said nebulizer means being adapted to feed into said nebulizer chamber a controlled stream of nebulized therapeutic agents, said stream of nebulized therapeutic agents being adapted to flow through said nebulizer chamber and mouth tube into the mouth of the patient for inhalation by the patient.
2. A face mask as defined in claim 1 wherein the nebulizer chamber is provided with a generally cylindrical smooth interior side wall.
3. A face mask as defined in claim 1 wherein the nebulizer chamber is provided with a side inlet port for supplying therein a stream of gas under pressure.
4. A face mask as defined in claim 1 wherein the nebulizer chamber is open at the top for receiving an adapter head for retaining an aerosol cartridge containing therapeutic agents, said cartridge having valve means for controlling the emission of a stream of nebulized therapeutic agents therefrom, and means in said adapter head for actuating said valve means. i
5. A face mask as defined in claim 1 wherein the nebulizer chamber is provided with an inlet port for supplying therein a stream of gas under pressure and said nebulizer chamber is open at the top and receives an adapter head, said adapter head being provided with a cylindrical bore and receiving an aerosol cartridge comprising and nebulizer means containing therapeutic agents and said cartridge having valve means for controlling the emission of a stream of nebulized therapeutic agents therefrom, and means in said adapter head for actuating said valve means. Y r
References Cited UNITED STATES PATENTS Meshberg 128-208 XR ANTON O. OECHSLE, Primary Examiner P. E. SHAPIRO, Assistant Examiner US. Cl. X.R. 128-173, 173.1
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US146730 *||Oct 10, 1873||Jan 20, 1874||Improvement in combined inhalers and dental props|
|US1418182 *||Dec 19, 1919||May 30, 1922||Tabor Benjamin C||Inhaler|
|US2123353 *||Apr 2, 1936||Jul 12, 1938||George Catt Samuel||Inhaler|
|US2788784 *||Aug 23, 1955||Apr 16, 1957||Birch Herbert M||Means for administering medication orally into the respiratory organs|
|US3012555 *||May 18, 1959||Dec 12, 1961||Philip Meshberg||Dispensing package for material under pressure|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3949743 *||Sep 6, 1974||Apr 13, 1976||Schick Incorporated||Medicated vapor production method and apparatus|
|US4011864 *||Oct 23, 1974||Mar 15, 1977||Paul Guichard||Respiratory apparatus|
|US4240418 *||Feb 28, 1979||Dec 23, 1980||Schering Aktiengesellschaft||Apparatus for the inhalation of medicinal agents|
|US4637387 *||May 27, 1983||Jan 20, 1987||Hall Lester B||Breathing apparatus|
|US5012803 *||Mar 6, 1989||May 7, 1991||Trudell Medical||Modular medication inhaler|
|US5012804 *||May 23, 1990||May 7, 1991||Trudell Medical||Medication inhaler with adult mask|
|US5178138 *||Sep 11, 1990||Jan 12, 1993||Walstrom Dennis R||Drug delivery device|
|US5497765 *||Jan 24, 1995||Mar 12, 1996||Rd-Chus Inc.||Device for the simultaneous delivery of beta-2 agonists and oxygen to a patient|
|US5645049 *||Jul 5, 1994||Jul 8, 1997||Trudell Medical Limited||Exhalation valve for face mask with spacer chamber connection|
|US5701886 *||Aug 7, 1995||Dec 30, 1997||Ryatt; Sadie||Treatment non-rebreather assembly and method for delivering oxygen and medication|
|US5765553 *||Nov 27, 1996||Jun 16, 1998||Diemolding Corporation||Aerosol medication delivery facemask adapter|
|US5769070 *||Oct 11, 1996||Jun 23, 1998||Istoria Farmaceutici S.P.A.||Device for the treatment of asthmatic patients, suitable for measuring the peak expiratory flow rate and for delivering drugs used in the treatment of asthma|
|US5842467 *||Jun 19, 1996||Dec 1, 1998||Greco; Michael||Metered dose inhaler and ambulatory manual breathing unit combination|
|US5988160 *||Apr 25, 1997||Nov 23, 1999||Trudell Medical Limited||Exhalation valve for face mask with spacer chamber connection|
|US6039042 *||Feb 23, 1998||Mar 21, 2000||Thayer Medical Corporation||Portable chamber for metered dose inhaler dispensers|
|US6202643||Jul 20, 1999||Mar 20, 2001||Thayer Medical Corporation||Collapsible, disposable MDI spacer and method|
|US6453900 *||Jun 9, 2000||Sep 24, 2002||Pulmonary Services, Inc.||Inhaler device|
|US6581590 *||Mar 21, 2000||Jun 24, 2003||Iep Pharmaceutical Devices Inc.||Inhalation actuated device|
|US6779521 *||Sep 14, 2000||Aug 24, 2004||Medic-Aid Limited||Combination mouthpiece for inhalation therapy devices used by oxygen dependent patients|
|US7004162||Sep 30, 1999||Feb 28, 2006||Canadian Monaghan, Ltd.||Exhalation valve|
|US7013896||May 6, 2002||Mar 21, 2006||Trudell Medical International||Mask with inhalation valve|
|US7647928||Feb 21, 2006||Jan 19, 2010||Activaero Gmbh||Inhalation device and inhalation device component|
|US7677244 *||Nov 14, 2003||Mar 16, 2010||Medi-Stream Pty Ltd||Drug delivery device and method|
|US7845354||Nov 19, 2002||Dec 7, 2010||Resmed Limited||Mask and vent assembly therefor|
|US7926487||Apr 19, 2011||Resmed Limited||Respiratory mask having gas washout vent and gas washout vent assembly for a respiratory mask|
|US7942150||May 17, 2011||Resmed Limited||Nasal assembly|
|US7946291 *||Apr 20, 2004||May 24, 2011||Novartis Ag||Ventilation systems and methods employing aerosol generators|
|US8122886 *||Dec 27, 2006||Feb 28, 2012||Resmed Limited||Respiratory mask assembly with vent|
|US8181650 *||May 22, 2012||Robert Fayette Andrew Nelson||Multitask medical treatment respiratory apparatus|
|US8528558||Mar 15, 2011||Sep 10, 2013||Resmed Limited||Respiratory mask having washout vent and gas washout vent assembly for a respiratory mask|
|US8757162||Nov 2, 2010||Jun 24, 2014||Resmed Limited||Nasal assembly|
|US8826910||Feb 11, 2013||Sep 9, 2014||Resmed Limited||Mask and vent assembly therefor|
|US8833371||Nov 11, 2010||Sep 16, 2014||Resmed Limited||Mask and vent assembly therefor|
|US9320866||Oct 19, 2015||Apr 26, 2016||Fisher & Paykel Healthcare Limited||Breathing assistance apparatus|
|US9333315||Sep 4, 2015||May 10, 2016||Fisher & Paykel Healthcare Limited||Breathing assistance apparatus|
|US9339622||Jul 2, 2015||May 17, 2016||Fisher & Paykel Healthcare Limited||Breathing assistance apparatus|
|US20030079751 *||Nov 19, 2002||May 1, 2003||Kwok Philip R.||Mask and vent assembly therefor|
|US20040014917 *||Sep 27, 2001||Jan 22, 2004||Thomas Eberle||Catalyst support, production and use thereof in the polymerization of olefins|
|US20050028811 *||Jun 24, 2004||Feb 10, 2005||Nelson Robert Fayette Andrew||Multitask medical treatment respiratory apparatus|
|US20050229927 *||Apr 20, 2004||Oct 20, 2005||Aerogen, Inc.||Ventilation systems and methods employing aerosol generators|
|US20050241644 *||Apr 8, 2005||Nov 3, 2005||Resmed Limited||Nasal assembly|
|US20060124129 *||Nov 14, 2003||Jun 15, 2006||Wharton David P||Drug delivery device and method|
|US20060191537 *||Feb 21, 2006||Aug 31, 2006||Activaero Gmbh||Inhalation device and inhalation device component|
|US20060196509 *||Apr 28, 2006||Sep 7, 2006||Resmed Limited||Respiratory mask having gas washout vent & gas washout vent assembly for a respiratory mask|
|US20070101998 *||Dec 27, 2006||May 10, 2007||Resmed Limited||Respiratory mask assembly with vent|
|US20080017198 *||Aug 6, 2007||Jan 24, 2008||Aerogen, Inc.||Aerosol delivery apparatus and method for pressure-assisted breathing systems|
|USD738508 *||Jun 11, 2013||Sep 8, 2015||Thomas Nichols||Personal care vaporizer device for the eye area|
|USD753352 *||Sep 24, 2014||Apr 5, 2016||Tonda Collins||Equine mask|
|EP0108145A1 *||May 12, 1983||May 16, 1984||Key Pharma||Device for delivery of a drug.|
|EP1695728A1 *||Feb 23, 2005||Aug 30, 2006||Activaero GmbH||Component for an inhalation device, an inhalation device with this component and a method of controlling for such a component|
|International Classification||A61M16/04, A61M16/06, A61M15/00|
|Cooperative Classification||A61M2016/0493, A61M15/009, A61M16/06, A61M15/00|
|European Classification||A61M15/00P, A61M15/00, A61M16/06|