Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS3561429 A
Publication typeGrant
Publication dateFeb 9, 1971
Filing dateMay 23, 1968
Priority dateMay 23, 1968
Publication numberUS 3561429 A, US 3561429A, US-A-3561429, US3561429 A, US3561429A
InventorsWalter C Bialobrzeski, Warren R Jewett
Original AssigneeEversharp Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Instrument for obtaining a biopsy specimen
US 3561429 A
Abstract  available in
Images(3)
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)

United States Patent [72] Inventors Warren R. Jewett [56] Reference Cited 8 M] b K C UNITED STATES PATENTS [2 A l N :3 ms 2,790,437 4/1957 Moore 128/2 pp o. 2,881,756 4/1959 Crosby et a1 128/2 [22] Filed May 23,1968 3 033 19 [45] Patented Fehg, 1971 4 5/1962 Lrppert 128/2 [73] Assi nee Eversharp Inc 3,084,691 4/1963 Stoner 128/278 g 3,173,414 3/1965 Guillant 128/2 3 253 524 5 1966 A h 1 5 1 by direct and mesne assignments 9 S 1Z3Wa et a 9 I Continuation-impart of application Ser. No. FOREIGN PATENTS 503,166, Oct. 23, 1965, now abandoned. 1,161,400 3/ 1958 France 128/2 136,009 1961 U.S.S.R. 128/2 146,433 1962 U.S.S.R. 128/2 Primary Examiner-Dalton L. Truluck Assistant Examinerl(yle L. Howell Attorneys-Delio and Montgomery and Jeremiah J. Duggan [54] INSTRUMENT FOR OBTAINING A BIOPSY SPECIMEN ABSTRACT: An instrument useful in obtaining biopsy 10Cla1ms 8Draw1n F s.

g lg specimens or the like from the body. In particular, the mstru- [52] US. Cl 128/2, ment is in the form of a gun having a triggerlike mechanism 128/305 which, in a single stroke, will activate a vacuum-producing [51] Int. Cl A6lb 10/00 means to draw a specimen into a tip supported by the gun and, Field of Search 128/2, 2B, thereafter, cause a portion of the specimen drawn into the tip 307, 309, 310, 31 1, 328, 276, 278, 305 to become severed.

VPATENTEDVFEB 919m 3.561.429

f sum 1 or 3 A INVENTORS warren Rdeiuei' WaHeY C Bla\obrzesK\ INSTRUMENT FOR OBTAINING A BIOPSY SPECIMEN This application is a continuation-impart of US. Pat. application Ser. No. 503,166 filed Oct. 23, 1965, now abandoned.

This invention relates to medical and surgical instruments and, more particularly, to an instrument for obtaining a specimen from a membrane body.

In order to avoid the difficulties of exploratory surgery, doctors rely on biopsy material obtained from the interior organs of the body by instruments inserted into the body through the mouth or other natural opening. Biopsy specimens from inaccessible regions of the body have, for the most part, been obtained by utilizing punch forceps and biting forceps. These instruments are fairly satisfactory but have the big disadvantage of requiring practice for the operator to gain facility in their use as well as a very high incidence of unsatisfactory material obtained. A specimen obtained with these instruments is frequently macerated because of the necessity of the operator having to make several bites to obtain the specimen. This is due in part to the dullness of the cutting edges of the instruments and in part to the design of the instruments themselves. In addition, these types of biopsy instruments are not without dangers, that is to say, they frequently require the operator to twist, pull and, sometimes, tear the mucosa being biopsied in order to obtain a specimen. Moreover, it is difficult for the operator to accurately gage the depth of the cut when using the punch or biting forceps.

In more recent years, another techniqueof intestinal biopsy has been advanced. This is the suction biopsy technique, wherein one person applies suction'to the tube of the instrument while a second person draws back on the cutting blade. These instruments cut cleanly and are associated with a low incidence of complications, such as bleeding, and the depth of the specimen can be controlled by the amount of suction applied to the instrument.

In their present form, these instruments are so constructed that two individuals are required to effect the obtaining of a specimen. Furthermore, it has been rather difficult to sequentially effectuate movement of the knife at the correct time, so as to accurately gage the amount of material being cut.

In view of the foregoing, a new and improved instrument for obtaining a specimen was required. The instrument must not only be operable by a single individual, but must also include means for controllably gaging the amount of material to be cut. Additionally, such an instrument must include means for pulling the material being biopsied into a portion of the instrument and thereafter sequentially actuating a cutting instrument at the proper moment to thereby sever a specimen of the right size.

Accordingly, it is an object of this invention to provide a new and improved instrument for obtaining a specimen.

Another object of this invention is to provide a new and improved instrument for accurately gaging-the amount of material to be severed from a membrane body.

Another object of the invention is to provide a new and improved biopsy instrument operable by one individual.

Still another object of the invention is to provide a new and improved biopsy instrument for drawing material therein and severing the material after a predetermined amount of material has been drawn into the instrument.

A further object of the invention is to provide a new and improved instrument for obtaining biopsy specimens from previously inaccessible areas of the human body.

Still other objects and advantages of the invention will in part be apparent and will in part appear hereinafter.

The invention accordingly comprises the features of construction, combinations of elements and arrangement of parts which will be exemplified in'the construction hereinafter set forth and the scope of the invention will be indicated in the claims.

For a fuller understanding of the nature and objects of the invention, reference should be had to the following detailed description, taken in connection with the accompanying drawings, in which:

FIG. 1 is a longitudinal sectional view of the instrument according to the invention;

FIG. 2 is a sectional view taken along line 2-2 of FIG. 1;

FIG. 3 is a top view of the invention with a cover portion removed;

FIG. 4 is a sectional view taken along line 4-4 of FIG. 1;

FIG. 5 is a top view, similar to FIG. 3, showing the position of some of the movable portions of the instrument;

FIG. 6 is a view similar to FIG. 5, showing the position of some of the movable portions of the invention at a later time;

FIG. 7 is a sectional side view of a modified form according to the invention; and

FIG. 8 is a sectional view taken along line 8-8 of FIG. 7.

Referring to FIGS. l 4, there is shown a housing 10 having a handle portion 11 and a front cap portion 12. The housing 10 may be constructed of plastic, wood, metal, or any other suitable material. An elongated hollow tube 14 having a fixedly positioned member 15 mounted thereon and a threaded flanged nut 16 surrounding the member 15, is coupled to a threaded plug 17. The plug 17 is itself threaded into the front cap portion 12. The tube 14 is provided with a hollow tip 20 having an opening 21 formed on one surface thereof for permitting a portion of a membrance body to be drawn into it. The tip 20 is preferably constructed of metal, but plastic or any other suitable material may be utilized. The tip 20 is removable from tube 14 to gain access to the specimen and for sterilization purposes.

Positioned within the tip 20 is a cutting member 24 which is slidably movable within the tip past the opening 21, such that any membrane material extending through opening 21 may be cut by the cutting edge 25 of the mechanism 24 as it moves past the opening. The cutting mechanism 24 should preferably have an edge engaging the inner cylindrical wall of the tip, such that it closes opening 21 after the cut has been made to prevent any tissue entering the opening 21 on the return of the cutting mechanism to its original position. In order to move the cutting mechanism 24 past the opening at a predetermined time, there is provided an actuating wire 27 extending through the tube 14 and into the interior of the housing 10 through plug 15 and cap 12. The wire 27 is slidably supported by member 30 which forms a portion of the suction or vacuumproducing means of the invention. The member 30 is mounted on a trigger 31 and is preferably resiliently biased by a spring 32 such that a force greater than a predetermined force is required to depress the trigger. The wire 14 threadedly engages cutting mechanism 24 such that the tip 20 and the cutting mechanism may be discarded and a new sterile unit substituted therefor.

The suction-producing means of the invention comprises bellows 35 mounted on one end to housing cap 12. It is coupled at its other end to member 30 in a manner such that, upon movement of member 30, the bellows 35 may be drawn to the left of FIG. 1 so as to suck air into the bellows. Positioned within the bellows is a filler plug 36 having a conduit 37 therethrough which is coupled to a conduit arrangement 38 in the cap 12. The arrangement 38 extends into a conduit 39 in plug 15 which cooperates with the interior of the tube 14. Also coupled to conduit 38 is a valve arrangement 40 for prcventing air from escaping when the bellows is drawn to the left of FIG. 1 and for permitting air to escape when the bellows is in a collapsed position. Additionally, to prevent the vacuum from escaping into the housing by way of the cap portion surrounding wire 27, a ball wire vacuum seal 43, preferably made of Teflon, is utilized. To produce a vacuum to draw a portion of a membrane body into the tip 20 through opening 21, the trigger is pulled to the left (FIG. 1), thereby expanding the bellows and causing a vacuum to be formed within tube 14 to draw the membrane into the tip portion. The bellows may be of the normally expanded type or normally collapsed type, although the latter is preferred. If the normally expanded type is utilized, the spring 32 should provide a greater force in order to cause the bellows to remain in a collapsed position until the trigger 31 is pulled.

In order to effectuate the timed movement of cutting mechanism 24 past the opening 21, there is provided a triggering mechanism generally shown at 45, comprising a block 48 fixedly mounted on wire 27. The block 48 cooperates with a cam follower 49a and spring mechanisms 49b and 490 positioned in a guide area 50 cut in the housing 10. A portion of the guide area 50 forms a cam surface generally shown at 51 for moving the member 49a as shown by the arrow 52 against the springs 49b and 49c when the member 30 contacts an adjustable screw member 53 threadedly mounted on the cam follower 49a at a rearward portion 49d. As clearly shown in FIGS. 1 and 3, member 53 is mounted loosely in a channel 54 cut into housing 10. The block 48 is also coupled to member 30 by way of a spring 55. Thus, as the trigger is pulled rear wardly, the vacuum is formed in tube 14 and tip 20 while, at the same time, spring 55 is being expanded. When the member 30 engages the threadedly adjustable screw 53, the cam follower 49a will pivot as shown by the arrow 52 against the cam 51 to permit the block to snap rearwardly until it hits a stop 56 as shown in FIG. 6. In this manner, the cutting mechanism 24 is snapped past the opening 21 to sever a portion of the membrane sucked therein.

It will be evident from FIGS. 1, 3 and that channel 54, having a diameter slightly larger than that of screw 53, permits sufficient rearward and vertical motion of the portion 49d so that the forward portion of member 49a slides along the edge of cam 51 in the direction of arrow 52 (FIG. 5).

The adjustable screw 53 permits the depth of cut to be controlled inasmuch as it limits the amount of vacuum supplied by the bellows prior to the actuating of the cutting mechanism. Therefore, to cut a larger specimen, the screw is adjusted such that the trigger must travel a greater distance prior to snapping the cutting mechanism 24 past opening 21.

In order to return the block 48 to its original blocked position, a tubular member 58 is slidably mounted on wire 27 and is of a dimension such that upon return of the member 30 to the right of FIG. 5, the side of the block 48 will be engaged by tubular member 58 and forced forward past the edge of the cam follower 49a.

As an additional improvement, the invention includes a member 60 mounted on the tube 14 for rotating the tip when the tip is inserted in the body from which a specimen is to be extracted. It is to be further understood that the tube 14 may be constructed of any suitable material such as plastic, metal, etc. Additionally, it is to be understood that the tube 14 may be rigid or flexible so as to permit its guidance into remote regions of the human body.

In operation, the instrument of this invention is generally placed in an endoscope tube which has been inserted in the region of the body from which the specimen is to be taken. The trigger 31 is then pulled rearwardly to form a vacuum and thereby pull a specimen into the tip 20. As the trigger eontinues its rearward movement, the adjustable screw 53 is contacted to trigger the cutting mechanism 24 past the opening 21 to sever the specimen. The instrument is then removed in the manner in which it was inserted and the specimen is taken from the tip.

Referring now to FIGS. 7 and 8, there is shown a modified form of the invention described in connection with FIGS. 1- 6. In place of the bellows shown in FIGS. 1-6, there is utilized a syringe for producing a vacuum. The instrument, according to this invention, is essentially in the form of a gun having a handle shown at 60 with an outer casing 61. The triggerlike mechanism 62 in the fonn of a ring is for permitting an index finger to move a member 63 slidable within a slot shown at 64 positioned within the casing 61. The member 63 is coupled to a member 65 having a caplike member 66 affixed thereto. Positioned within the casing 61 and supported by the sidewall thereof are syringe support elements 68. The syringe shown at 69 having a piston 70 is inserted within the casing. The member 70 fits within the cap member 66 and the piston 70 is movable therewith. The syringe element 69 is provided with a screwable insert tip member 73 which is coupled to a plastic (or other type material) tubing 74 which is itself coupled to a tube member 75. The tube 75 extends into a passage shown at 78 formed within the rodlike member 79 connected to the casing 61 by a coupling joint 80.

A tip, such as disclosed in FIGS. 1-6, and shown at 81, is supported at the end of the member 79 and has an opening 82 for permitting a specimen to be drawn therein. The syringe 69 as well as its cooperating tubings 74 and 75 provide a vacuum which will draw a specimen into the tip 81 through the opening 82.

Positioned within the tip 81 is a severing member which moves past the window or opening 82 to sever a piece of tissue (specimen) drawn therein. The severing member 85 is connected to a wire 86 which is in turn looped at 88 about a member 87. The member 87 is slidably movable within the coupling member 80. In order to effect movement of the member 87 to move the severing knife 85, there is provided a member 89 which is supported on two pins shown at 90 and 91, respectively. The pins 90 and 91 are themselves supported by the casing 61 in a manner not shown. The member 89 is provided with two slots. 92 and 93, respectively, the slot 92 being in the direction of movement of the member 87 whereas, in the preferred embodiment, slot 93 is positioned at an angle of about 45. It should be understood that this angle could be varied.

The member 89 is supported at its rear by a sponge like spring member 95, such as of foam rubber, which is itself supported from a member 96 formed as part of the housing. The member 65 supports a tube shown at 99 having a slot 100 cut therein, in which there is movable a bar 101 supported by a threaded screw member 102 so as to position the bar 101 within the tube 99. The bar 101 is movable by the use of a knob 103 by way of a flat 104 shown on the screw member 102. The fiat permits the screw member 102 to be rotated by the knob 103 but permits screw member 102 to slide therein.

A member 97 is coupled to the member 99 by means of a spring 105. A pin 106 is also provided on the member 89 and cooperates with the bar 101'. In operation, the bar 101 is moved rearwardly as the member 65 moves rearwardly and engages pin 106 causing the member 89 to move rearwardly. This in turn causes member 89 to pivot and release the member 97 which, by way of the spring 105, forces the member 87 rearwardly and this, in turn, causes the severing knife to move rearwardly past the opening 82. The spring is of sufficient resiliency to force the member 89 to return to its original position after the member 97 is returned to the position shown in FIG. 8.

Thus, by the operation of a triggerlike mechanism, a vacuum is first formed to draw tissue into the opening of the tip 81 and thereafter, in a single stroke, causes the severing knife to move rearwardly to sever tissue drawn within the tip. By adjusting the position of the knob 103 and, thus the bar 101, the amount of vacuum required may be varied since the syringe will pull back a lesser amount if the bar 101 is moved toward the front of the instrument.

It will thus be seen that the objects set forth above, among those made apparent from the preceding description, are efficiently attained and since certain changes may be made in the foregoing construction without departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawings shall be interpreted as illustrative and not in a limiting sense.

It is to be understood that the following claims are intended to cover all the generic and specific features of the invention herein described and all statements of the scope of the invention which, as a matter of language, might be said to fall therebetween.

We claim:

1. An instrument for obtaining a specimen from a membrane body, comprising a housing, a hollow tube extending from said housing, tip means positioned on one end of said tube, said tip having an opening in a wall thereof, cutting means positioned in said tip and movable past the opening in said tip, vacuum-producing means mounted in said housing and having a movable portion for producing the vacuum, a vacuum conduit between said tube and said vacuum-producing means, means for actuating said vacuum-producing means to draw a portion of the membrane body into the tip and move said cutting means past said tip opening to sever a specimen from'said membrane body drawn into said tip; said actuating means including a trigger, a first member for moving the vacuum-producing means movable portion coupled to said trigger, a wire extending through the tube and connected to the severing means at one end and supported by said first member at its other end, a block responsive to movement of said wire, means connected between said block and said first member for resiliently biasing said block, a cam follower positioned to prevent movement of the block while said first member is being moved over a portion of its travel, and an abutment member positioned on said cam follower in the line of travel of said first member such that upon contact of said first member and said abutment member, said cam follower is moved to release said block, whereby said cutting means is moved.

2. An instrument in accordance with claim 1 including means mounted on the cam follower adjustable so as to set the amount of vacuum provided prior to moving the cutting means.

3. An instrument in accordance with claim 1 including a tubular member slidably mounted on the wire and positioned to engage said block and said first member.

4. An instrument according to claim 1 in which said vacuum-producing means comprises a syringe having a piston, said piston adapted to move with said actuating means.

5. An instrument according to claim 1 in which said vacuum-producing means is a bellows which is actuated to produce a vacuum by the movement of said actuating means.

6. An instrument according to claim 1 including means mounted on said hollow tube for rotating said tip.

7. An instrument according to claim 1 in which said actuating means includes means for setting the amount of vacuum provided to said tube prior to moving the severing member.

8. An instrument according to claim 1 in which said abutment member comprises an adjustable screw and said block is mounted on said wire.

9. An instrument according to claim 1 in which said abutment member comprises a pin.

10. An instrument according to claim 1 including means mounted on said housing for resiliently biasing said cam follower.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2790437 *Oct 12, 1955Apr 30, 1957Welch Allyn IncSurgical instrument
US2881756 *Feb 3, 1958Apr 14, 1959Crosby William HIntestinal biopsy capsule
US3033194 *Nov 8, 1960May 8, 1962Lippert Henry EBiopsy capsule and apparatus
US3084691 *Nov 4, 1960Apr 9, 1963Air ShieldsAspirator
US3173414 *Mar 6, 1962Mar 16, 1965Levallois Optique Et PrecBiopsy probe, and combination thereof with an endoscope
US3253524 *Jan 2, 1963May 31, 1966Olympus Optical CoFlexible tube assembly
FR1161400A * Title not available
SU136009A * Title not available
SU146433A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3831585 *Jul 19, 1972Aug 27, 1974T BrondyRetrograde renal biopsy device
US3989033 *Dec 5, 1974Nov 2, 1976David Marcos HalpernSurgical instrument for biopsies
US4246902 *Mar 10, 1978Jan 27, 1981Miguel MartinezSurgical cutting instrument
US4445517 *Sep 28, 1981May 1, 1984Feild James RodneySuction dissector
US4522206 *Jan 26, 1983Jun 11, 1985Dyonics, Inc.For cutting a range of body tissue
US4603694 *Mar 8, 1983Aug 5, 1986Richards Medical CompanyArthroscopic shaver
US4662371 *Jun 10, 1985May 5, 1987Whipple Terry LSurgical instrument
US4669469 *Feb 28, 1986Jun 2, 1987Devices For Vascular InterventionSingle lumen atherectomy catheter device
US4753234 *Nov 3, 1986Jun 28, 1988Miguel MartinezSurgical cutting instrument having a offset probe for ophthalmic surgery
US4768506 *Sep 26, 1985Sep 6, 1988Alcon Laboratories, Inc.Handpiece drive apparatus for powered surgical scissors
US4776346 *May 14, 1986Oct 11, 1988Dan BerahaBiopsy instrument
US4781186 *Jul 31, 1987Nov 1, 1988Devices For Vascular Intervention, Inc.For use in a vessel
US4838281 *Oct 13, 1987Jun 13, 1989Alcon Laboratories, Inc.Linear suction control system
US4989614 *Feb 23, 1988Feb 5, 1991Vance Products IncorporatedFine-needle aspiration cell sampling methods
US5025797 *Mar 29, 1989Jun 25, 1991Baran Gregory WAutomated biopsy instrument
US5069224 *Jun 8, 1990Dec 3, 1991Zinnanti Jr AnthonyEndometrial aspirator
US5121751 *Mar 16, 1990Jun 16, 1992Ryder International CorporationInstrument for tissue sampling
US5125413 *Apr 17, 1991Jun 30, 1992Baran Gregory WAutomated biopsy instrument
US5172701 *Feb 28, 1990Dec 22, 1992Medical Device Technologies, Inc.Single use automated soft tissue aspiration biopsy device
US5213110 *Mar 16, 1992May 25, 1993Du-Kedem Projects Ltd.Pistol-grip vacuum soft tissue biopsy device
US5249583 *Nov 9, 1992Oct 5, 1993Vance Products IncorporatedElectronic biopsy instrument with wiperless position sensors
US5395312 *May 10, 1993Mar 7, 1995Desai; AshvinSurgical tool
US5469860 *Oct 27, 1994Nov 28, 1995De Santis; Stephen A.Manually operated aspirating device
US5511556 *Apr 11, 1994Apr 30, 1996Desantis; Stephen A.Needle core biopsy instrument
US5560373 *Apr 6, 1995Oct 1, 1996De Santis; Stephen A.Needle core biopsy instrument with durable or disposable cannula assembly
US5674232 *Sep 20, 1996Oct 7, 1997Halliburton; Alexander GeorgeMethod of excising an obstruction from a body channel
US5713368 *Sep 13, 1995Feb 3, 1998Medical Device Technologies, Inc.Single use automated soft tissue aspiration biopsy device
US5779647 *Jun 7, 1995Jul 14, 1998Chau; SonnyAutomated biopsy instruments
US5817033 *Jun 10, 1996Oct 6, 1998Desantis; Stephen A.Needle core biopsy device
US5833643 *Nov 18, 1997Nov 10, 1998Scieran Technologies, Inc.Apparatus for performing ophthalmic procedures
US5971939 *Apr 22, 1998Oct 26, 1999Laurus Medical CorporationNeedle core biopsy device
US6019733 *Sep 18, 1998Feb 1, 2000United States Surgical CorporationBiopsy apparatus and method
US6050955 *Sep 18, 1998Apr 18, 2000United States Surgical CorporationBiopsy apparatus and method
US6077231 *Nov 17, 1997Jun 20, 2000United States Surgical CorporationApparatus and method for localizing and removing tissue
US6142955 *Feb 20, 1998Nov 7, 2000United States Surgical CorporationBiopsy apparatus and method
US6165137 *Sep 16, 1999Dec 26, 2000United States Surgical CorporationApparatus and method for localizing and removing tissue
US6193673Feb 19, 1999Feb 27, 2001United States Surgical CorporationBiopsy instrument driver apparatus
US6197041Sep 15, 1993Mar 6, 2001United States Surgical CorporationTrocar
US6258111Aug 5, 1999Jul 10, 2001Scieran Technologies, Inc.Apparatus and method for performing ophthalmic procedures
US6358260Apr 20, 1998Mar 19, 2002Med-Logics, Inc.Automatic corneal shaper with two separate drive mechanisms
US6425905Nov 29, 2000Jul 30, 2002Med-Logics, Inc.Method and apparatus for facilitating removal of a corneal graft
US6428508Feb 1, 2000Aug 6, 2002Enlighten Technologies, Inc.Pulsed vacuum cataract removal system
US6436054Nov 24, 1999Aug 20, 2002United States Surgical CorporationBiopsy system
US6488636Jun 7, 2001Dec 3, 2002United States Surgical CorporationBiopsy apparatus
US6554779Feb 16, 2001Apr 29, 2003United States Surgical CorporationBiopsy instrument driver apparatus
US6626850Mar 30, 1998Sep 30, 2003Allegiance CorporationAutomated biopsy instruments
US6638235May 23, 2001Oct 28, 2003Suros Surgical Systems, Inc.Biopsy apparatus
US6663644Jun 2, 2000Dec 16, 2003Med-Logics, Inc.Cutting blade assembly for a microkeratome
US6699285Feb 9, 2001Mar 2, 2004Scieran Technologies, Inc.Eye endoplant for the reattachment of a retina
US6702832Oct 15, 2002Mar 9, 2004Med Logics, Inc.Medical device for cutting a cornea that has a vacuum ring with a slitted vacuum opening
US6712773Sep 11, 2000Mar 30, 2004Tyco Healthcare Group LpBiopsy system
US6758824Nov 6, 2000Jul 6, 2004Suros Surgical Systems, Inc.Biopsy apparatus
US6814743Dec 26, 2001Nov 9, 2004Origin Medsystems, Inc.Temporary seal and method for facilitating anastomosis
US6860860Nov 19, 2001Mar 1, 2005Tyco Healthcare Group, LpTissue sampling and removal apparatus and method
US7189207May 23, 2003Mar 13, 2007Tyco Healthcare Group LpBiopsy system having a single use loading unit operable with a trocar driver, a knife driver and firing module
US7311700Nov 29, 2000Dec 25, 2007Med-Logics, Inc.LASIK laminar flow system
US7390306Oct 14, 2004Jun 24, 2008Suros Surgical Systems, Inc.Vacuum assisted biopsy needle set
US7399310Dec 16, 2003Jul 15, 2008Edrich Vascular Devices, Inc.Endovascular stapler
US7458940Jul 28, 2004Dec 2, 2008Suros Surgical Systems, Inc.Biopsy apparatus
US7497833Oct 21, 2004Mar 3, 2009Suros Surgical Systems, Inc.Biopsy apparatus with vacuum relief
US7497862Aug 5, 2002Mar 3, 2009Tyco Healthcare Group LpTissue marking apparatus and method
US7513877Jun 3, 2004Apr 7, 2009Tyco Healthcare Group LpTissue sampling and removal apparatus and method
US7544203Sep 27, 2004Jun 9, 2009Maquet Cardiovascular LlcTemporary seal and method for facilitating anastomosis
US7556622May 18, 2005Jul 7, 2009Suros Surgical Systems, Inc.Selectively openable tissue filter
US7569057 *Sep 9, 2004Aug 4, 2009Warsaw Orthopedic, Inc.Impulsive percussion instruments for endplate preparation
US7670299Mar 7, 2006Mar 2, 2010Ethincon Endo-Surgery, Inc.Device for minimally invasive internal tissue removal
US7806834 *Mar 7, 2006Oct 5, 2010Devicor Medical Products, Inc.Device for minimally invasive internal tissue removal
US7837630Feb 10, 2006Nov 23, 2010Suros Surgical Systems, Inc.Fluid control element for biopsy apparatus
US7883476Feb 28, 2006Feb 8, 2011Suros Surgical Systems, Inc.Selectively detachable outer cannula hub
US7947062Apr 15, 2002May 24, 2011Maquet Cardiovascular LlcTemporary anastomotic seal and method
US7988642Feb 28, 2008Aug 2, 2011Suros Surgical Systems, Inc.Vacuum assisted biopsy device
US8002713 *Mar 5, 2003Aug 23, 2011C. R. Bard, Inc.Biopsy device and insertable biopsy needle module
US8012102Mar 1, 2007Sep 6, 2011C. R. Bard, Inc.Quick cycle biopsy system
US8016772Mar 1, 2007Sep 13, 2011C. R. Bard, Inc.Biopsy device for removing tissue specimens using a vacuum
US8025656Nov 6, 2007Sep 27, 2011Hologic, Inc.Methods, systems and devices for performing gynecological procedures
US8048003Sep 5, 2008Nov 1, 2011Suros Surgical Systems, Inc.Vacuum assisted biopsy device
US8052614Dec 30, 2009Nov 8, 2011C. R. Bard, Inc.Biopsy device having a vacuum pump
US8052615Jul 8, 2005Nov 8, 2011Bard Peripheral Vascular, Inc.Length detection system for biopsy device
US8109885Mar 17, 2003Feb 7, 2012C. R. Bard, Inc.Biopsy device for removing tissue specimens using a vacuum
US8109886Aug 12, 2003Feb 7, 2012Suros Surgical Systems, Inc.Biopsy apparatus
US8128577Jan 16, 2007Mar 6, 2012Tyco Healthcare Group LpBiopsy system
US8133237Mar 18, 2008Mar 13, 2012Restoration Robotics, Inc.Biological unit removal tools with concentric tubes
US8157744Jul 8, 2005Apr 17, 2012Bard Peripheral Vascular, Inc.Tissue sample flushing system for biopsy device
US8162850 *Dec 16, 2008Apr 24, 2012Devicor Medical Products, Inc.Hand actuated tetherless biopsy device with scissors grip
US8162851Oct 5, 2010Apr 24, 2012C. R. Bard, Inc.Biopsy needle system having a pressure generating unit
US8167818Jan 26, 2009May 1, 2012Suros Surgical Systems, Inc.Biopsy apparatus with vacuum relief
US8187204Feb 14, 2008May 29, 2012Suros Surgical Systems, Inc.Surgical device and method for using same
US8192370Oct 27, 2008Jun 5, 2012Suros Surgical Systems, Inc.Biopsy apparatus
US8202229Oct 1, 2007Jun 19, 2012Suros Surgical Systems, Inc.Surgical device
US8226664Mar 13, 2009Jul 24, 2012Restoration Robotics, Inc.Biological unit removal tools with movable retention member
US8231544May 21, 2008Jul 31, 2012Suros Surgical Systems, Inc.Vacuum assisted biopsy needle set
US8251917Aug 17, 2007Aug 28, 2012C. R. Bard, Inc.Self-contained handheld biopsy needle
US8262585Aug 10, 2006Sep 11, 2012C. R. Bard, Inc.Single-insertion, multiple sampling biopsy device with linear drive
US8262586Oct 23, 2007Sep 11, 2012C. R. Bard, Inc.Large sample low aspect ratio biopsy needle
US8267868Aug 10, 2006Sep 18, 2012C. R. Bard, Inc.Single-insertion, multiple sample biopsy device with integrated markers
US8277393May 18, 2004Oct 2, 2012Suros Surgical Systems, Inc.Biopsy apparatus
US8282574Aug 10, 2006Oct 9, 2012C. R. Bard, Inc.Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8283890Sep 25, 2009Oct 9, 2012Bard Peripheral Vascular, Inc.Charging station for battery powered biopsy apparatus
US8292909 *Jul 16, 2012Oct 23, 2012Laurimed, LlcDevices and methods for cutting tissue
US8298246Apr 1, 2010Oct 30, 2012Restoration Robotics, Inc.Follicular unit removal tool with pivoting retention member
US8298254 *Jun 30, 2011Oct 30, 2012Laurimed, LlcDevices and methods for cutting and evacuating tissue
US8357103Mar 24, 2006Jan 22, 2013Suros Surgical Systems, Inc.Vacuum assisted biopsy needle set
US8366636Jul 8, 2005Feb 5, 2013Bard Peripheral Vascular, Inc.Firing system for biopsy device
US8430824Oct 29, 2009Apr 30, 2013Bard Peripheral Vascular, Inc.Biopsy driver assembly having a control circuit for conserving battery power
US8430827Sep 23, 2011Apr 30, 2013Suros Surgical Sysytems, Inc.Vacuum assisted biopsy device
US8454532Nov 11, 2010Jun 4, 2013Devicor Medical Products, Inc.Clutch and valving system for tetherless biopsy device
US8465471Aug 5, 2010Jun 18, 2013Rocin Laboratories, Inc.Endoscopically-guided electro-cauterizing power-assisted fat aspiration system for aspirating visceral fat tissue within the abdomen of a patient
US8485987Oct 5, 2007Jul 16, 2013Bard Peripheral Vascular, Inc.Tissue handling system with reduced operator exposure
US8485989Sep 1, 2009Jul 16, 2013Bard Peripheral Vascular, Inc.Biopsy apparatus having a tissue sample retrieval mechanism
US8528563Apr 4, 2008Sep 10, 2013Hologic, Inc.Systems, methods and devices for performing gynecological procedures
US8529468Jul 1, 2009Sep 10, 2013Suros Surgical Systems, Inc.Surgical system
US8568332May 25, 2012Oct 29, 2013Suros Surgical Systems, Inc.Biopsy apparatus
US8574167Jul 26, 2010Nov 5, 2013Devicor Medical Products, Inc.Needle for biopsy device
US8574253Apr 4, 2008Nov 5, 2013Hologic, Inc.Method, system and device for tissue removal
US8585610 *Jun 28, 2011Nov 19, 2013Depuy Mitek, LlcTissue extraction and maceration device
US8597205Jul 17, 2012Dec 3, 2013C. R. Bard, Inc.Biopsy device
US8597206Oct 12, 2009Dec 3, 2013Bard Peripheral Vascular, Inc.Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8627992 *May 3, 2004Jan 14, 2014Edrich Health Technologies, Inc.Endovascular stapler
US8647349Sep 7, 2007Feb 11, 2014Hologic, Inc.Systems for performing gynecological procedures with mechanical distension
US8657842Jul 12, 2013Feb 25, 2014Laurimed, LlcDevices and methods for cutting tissue
US8679032Jan 17, 2013Mar 25, 2014Suros Surgical Systems, Inc.Vacuum assisted biopsy needle set
US8685052Jan 4, 2013Apr 1, 2014Laurimed, LlcDevices and methods for cutting tissue
US8690793Mar 16, 2009Apr 8, 2014C. R. Bard, Inc.Biopsy device having rotational cutting
US8696686Jun 26, 2012Apr 15, 2014Restoration Robotics, Inc.Biological unit removal tools with movable retention member
US8702621Apr 29, 2011Apr 22, 2014C.R. Bard, Inc.Quick cycle biopsy system
US8702622Aug 10, 2011Apr 22, 2014C.R. Bard, Inc.Quick cycle biopsy system
US8708928Apr 15, 2009Apr 29, 2014Bard Peripheral Vascular, Inc.Biopsy apparatus having integrated fluid management
US8708929Mar 12, 2013Apr 29, 2014Bard Peripheral Vascular, Inc.Biopsy apparatus having integrated fluid management
US8708930Mar 13, 2013Apr 29, 2014Bard Peripheral Vascular, Inc.Biopsy apparatus having integrated fluid management
US8721563Aug 28, 2012May 13, 2014C. R. Bard, Inc.Single-insertion, multiple sample biopsy device with integrated markers
US8728003Aug 28, 2012May 20, 2014C.R. Bard Inc.Single insertion, multiple sample biopsy device with integrated markers
US8728004Apr 12, 2012May 20, 2014C.R. Bard, Inc.Biopsy needle system having a pressure generating unit
US8764679Aug 5, 2013Jul 1, 2014Suros Surgical Systems, Inc.Biopsy apparatus
US8771200Aug 22, 2012Jul 8, 2014C.R. Bard, Inc.Single insertion, multiple sampling biopsy device with linear drive
US8808197Mar 14, 2013Aug 19, 2014Bard Peripheral Vascular, Inc.Biopsy driver assembly having a control circuit for conserving battery power
US8808200Oct 24, 2012Aug 19, 2014Suros Surgical Systems, Inc.Surgical device and method of using same
US8814882 *Mar 18, 2008Aug 26, 2014Restoration Robotics, Inc.Biological unit removal tools with retention mechanism
US8815099Jan 21, 2014Aug 26, 2014Laurimed, LlcDevices and methods for filtering and/or collecting tissue
US8834487Jul 23, 2010Sep 16, 2014Hologic, Inc.Systems and methods for preventing intravasation during intrauterine procedures
US8840625Sep 7, 2007Sep 23, 2014Hologic, Inc.Systems for performing gynecological procedures with closed visualization lumen
US8840626Sep 7, 2007Sep 23, 2014Hologic, Inc.Systems for performing gynecological procedures with simultaneous tissue cutting and removal
US8840632Oct 22, 2012Sep 23, 2014Laurimed, LlcDevices and methods for cutting tissue
US20080234602 *Mar 18, 2008Sep 25, 2008Oostman Clifford ABiological unit removal tools with retention mechanism
US20110257558 *Jun 28, 2011Oct 20, 2011Depuy Mitek, Inc.Tissue extraction and maceration device
US20120004595 *Jun 30, 2011Jan 5, 2012Laurimed, LlcDevices and methods for cutting and evacuating tissue
USRE33569 *May 19, 1989Apr 9, 1991Devices For Vascular Intervention, Inc.Single lumen atherectomy catheter device
EP0010321A1 *Oct 1, 1979Apr 30, 1980Del Re Renzo Dr. BrunDevice for the single-handed operation of a biopsy instrument
EP0120825A1 *Feb 23, 1984Oct 3, 1984Jan Ingemar NäslundA cell sampling apparatus
WO1988007839A1 *Apr 15, 1988Oct 20, 1988James TaylorSampling device
WO1994028803A1 *Jun 10, 1994Dec 22, 1994Hec Medical Arts LtdCatheter and method of use thereof
WO1999015079A1 *Sep 16, 1998Apr 1, 1999United States Surgical CorpBiopsy apparatus and method
Classifications
U.S. Classification600/565, 606/171
International ClassificationA61B17/30, A61B10/04, A61B17/22, A61B10/00
Cooperative ClassificationA61B10/04, A61B17/320783, A61B2017/306
European ClassificationA61B10/04