Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS3563240 A
Publication typeGrant
Publication dateFeb 16, 1971
Filing dateJul 20, 1966
Priority dateJul 20, 1966
Publication numberUS 3563240 A, US 3563240A, US-A-3563240, US3563240 A, US3563240A
InventorsJules Silver
Original AssigneeJules Silver
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Dual unit syringe
US 3563240 A
Images(1)
Previous page
Next page
Description  (OCR text may contain errors)

United States Patent 218M, 218N, 218NV, 218?, 218PA, 218.1, 218.2, 221, 272; 222/145, 309; 128/225, 234, 235, 239, 261

ll, /0 ll [56] References Cited UNITED STATES PATENTS 2,856,925 10/1958 Helmer et a1. 128/218 3,276,632 10/1966 Stanzel 222/83.5 3,326,416 6/1967 Hayes 222/145X 3,354,883 1 H1967 Southerland 128/272X Primary Examiner- Richard A. Gaudet Assistant Examiner-Kyle L. Howell Atlorney- Rommel & Rommel ABSTRACT: A dual unit syringe capable of supporting a pluralit'y of isolated medicaments or pharmaceuticals separated one from the other under such circumstances that they will be maintained in stable form for long shelf life. The syringe has means using one liquid medicament and a cannula containing another and different liquid medicament under such circumstances that the medicaments can be mixed in and expelled from the cannula in blended form.

DUAL UNIT SYRINGE This invention relates to a dual unit syringe capable of supporting a plurality of isolated medicaments or pharmaceuticals. The medicaments are separated from one another under such circumstances that they will be maintained in stable form and properly packaged for long shelf life. The syringe parts are so associated that the medicaments can, with ease, at the time of intended use, be properly blended and applied.

The primary object of this invention is the provision of a dual unit syringe which is adapted to be used for admixing a plurality of pharmaceuticals, one of the pharmaceuticals being penicillin. Penicillin is sensitive to various bases and other drugs frequently necessary to be added thereto as a supplement. It is easily destroyed or degraded when compounded with other pharmaceuticals. it is necessary therefore to isolate penicillin and maintain it in a very stable form. Therefore, the dual unit syringe of this invention comprises means for isolating the penicillin under such circumstances that the syringe can be manipulated for expelling medicinal supplements into penicillin and applying the resultant mixture.

A further object of this invention is the provision of a dual unit syringe which consist of a main tubular body adapted to receive a pharmaceutical or pharmaceuticals, and having as sociated therewith a cannula adapted to isolate penicillin under such circumstances that at the time of use the pharmaceuticals of the tubular body may be expelled into and through the penicillin of the cannula and the resultant mixture applied as desired. I

A further object of this invention is the provision of a convenient and satisfactory means of packaging and maintaining a multiple dose syringe with medicinal ingredients thereof separated until desired to be used, and under such circumstances that the syringe may be operated to cause admixture of the ingredients and application at a desired time.

A further object of this invention is the provision of a dual unit syringe capable of handling a plurality of medicaments respectively isolated from each other within the syringe, and under such circumstances that they may be admixed at the proper time and applied. One such use would be infusing the mammary gland of a cow through the teat canal.

Other objects and advantages of this invention will be apparent during the course of the following detailed description, taken in connection with the accompanying drawing, forming portions of this specification, and in which drawing:

FIG. 1 is a side elevation of the assembled dual unit syringe.

FIG. 2 is a longitudinal cross-sectional view taken through the syringe showing the parts of the same ready for medicinal application.

FIG. 3 is a side elevation of a different form of dual unit syringe in which expulsion power is received from an aerosol container.

H6. 4 is a vertical cross-sectional view taken through a cannula adapted to isolate penicillin under such circumstances that it can be maintained for a prolonged shelf life prior to compounding.

FIG. 5 is a fragmentary view, partly in section, showing the upper end of a tubular body or container adapted to receive one or more pharmaceuticals.

FIG. 6 is a cross-sectional view taken on the line 6-6 of FIG. 2.

In the drawing, wherein for the purpose of illustration are shown different forms of the invention, and wherein similar reference characters designate corresponding parts throughout the several views, the letter A may generally designate the preferred form of invention and B a modification thereof. ln both forms of invention a cannula 10 is provided, which may be of any desirable material, preferably a synthetic plastic, It comprises an elongated tubular body 11 which at the upper end thereof tapers at 12 in an upward converging relation. It is provided withan applicator nozzle inserting stem or needle 13 of uniform diameter from end to end. The body 11 has a chamber 12 therein adapted to receive penicillin, or some other pharmaceutical which is intended to be expelled through the tapered passageway 14 of the neck 12 and then through the duct 15 of the applicator tube 13. A removable cap 16 normally seals the outer end of the nozzle 13. The tubular body 11 intermediate the ends thereof is provided with a rupturable membrane 20 adapted to seal off the chamber 12 for the purpose of isolating the body of penicillin 21 in liquid form. The tubular body 11 below the membrane 20 has a socket 22 and a base flange 23; the socket 22 being adapted to receive a tubular nozzle 25 at the outer or upper end of the syringe tubular body 30.

The tubular body 30 is preferably made of plastic and is of uniform diameter from end to end. It has a chamber 31 therein adapted to receive one or more supplemental medicaments. At its outer end it is provided with an end wall 32, upon which the nozzle 25 is mounted; a duct 34 extending through the wall 32 and the nozzle 25. The tubular body 30 at the lower end thereof is provided with laterally extending handle or finger flanges 36 as shown in the drawing. The chamber 31 is of uniform diameter from end to end and opens at the same diameter at the lower end of the tubular body 30. It is adapted to receive one or more supplemental pharmaceuticals, such as neomycin, dihydrostreptomycin, hydrocortisone or sulfonamides.

ln the form of invention A the means for expelling the liquid pharmaceuticals from the tubular body 30 into the cannula and through the medicament therein may comprise a single dose plunger or a plunger 40 which consists of a body formed of a plurality of radially extending flat flanges 60, connected centrally at 61. They are notched at 62 at the outer edges thereof. The upper ends of these flanges support a slidable plunger head 64 of flexible plastic or other suitable material. lt is adapted for insertion through the bottom opening of the chamber 31 and operates in leak-proof sliding relation in the chamber 31. The flanges 61 at the lower ends thereof support a palm engaging base or flange 66. A plunger limiting nut or ring 67 is threaded in the notches 62 having a segmental rib 68 thereon for such purpose. Rotation of the nut or ring 67 enables it to be properly located along the length of the plunger so as to permit a proper dosage of the amount of the medicament or combination of medicament 70 from ,the chamber 31 to be expelled into and through the cannula 10.

In the areosol type of syringe B, the cannula 10 is similar in structure to that above described. It also includes an aerosol container adapted to receiver the medicaments in liquified gas. The container 80 has an adapter cap 81 with a nozzle 25" similar to the nozzle 25 of the form of invention A and for the same purpose. The cap 81 is provided with an operating handle 82 which may be manipulated as by tilting, as with conventional aerosol syringes to release the medicament and gas from the container 80 for the admixture with penicillin as it passes through the cannula 10.

It will be noted in the form of invention A that the syringe barrel or tube 30 has a plunger adapted to divide the combination of medicaments 70 into four doses. As before stated, the plunger may provide for a single dose or a multiple dose. In the multiple dose the assembly should include a number of loaded cannulas 10 with the medicament 21 in amount equivalent to the number of doses. to be disbursed from chamber 31. The package as sold may comprise the equipment above described and with each syringe barrel there is provided four cannulas 10, each loaded with penicillin or some other medicament. The user can remove an empty cannula after administering one dose and continue using the same syringe barrel for the application of the remaining three doses.

Various changes in the size, shape and arrangement of parts may be made to the forms of invention herein shown and described, without departing from the spirit of the invention or the scope of the claims.

lclaim:

1. in a dual unit medicament dispensing syringe the combination of a tubular body having a chamber therein containing a liquid medicament and having a reduced top discharged nozzle provided with a passageway therethrough communicating with the chamber, the chamber at the lower end of said tudischarge passage communicatng with said cannula chamber, said cannula at is its opposite end from said applicator having a sealing disc disposed inwardly a sufiicient distance from said end to provide an opened ended socket receiving the nozzle of the tubular body, said socket being of such length that when the nozzle is fully inserted therein it will rupture the disc, and a removable sealing cap for the reduced end of said cannula.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2856925 *Nov 25, 1957Oct 21, 1958EastonSyringe structure
US3276632 *Apr 2, 1965Oct 4, 1966Stanzel George ARepellent fluid-dispensing weapon
US3326416 *Jan 14, 1966Jun 20, 1967Du PontApparatus for codispensing a plurality of liquids
US3354883 *Mar 8, 1965Nov 28, 1967Lee Southerland ElizabethDisposable syringe having frangible means for mixing plural medicaments
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3789844 *Sep 10, 1971Feb 5, 1974Burges AFoil sealed syringe
US4275729 *Oct 29, 1979Jun 30, 1981Jules SilverAdjustable dosage syringe
US4723938 *Dec 24, 1986Feb 9, 1988Schneider-Shiley (Usa) Inc.Single plunger inflation device for angioplasty catheter
US4750373 *Jan 22, 1987Jun 14, 1988Shapiro Justin JAdjustable volume, pressure-generating pipette sampler
US4874385 *Dec 16, 1987Oct 17, 1989Sherwood Medical CompanyPlunger lock device
US5320845 *Jan 6, 1993Jun 14, 1994Py Daniel CApparatus for delivering multiple medicaments to an eye without premixing in the apparatus
US5322800 *Aug 13, 1993Jun 21, 1994The United States Of America As Represented By The Secretary Of The InteriorSyringe containing salt solution and ion exchange filter to generate acid or base when actuated
US5328486 *Nov 19, 1991Jul 12, 1994American Cyanamid CompanySyringe for dispensing multiple dosages
US5344409 *Jun 14, 1993Sep 6, 1994Genesis Industries Inc.Syringe latch
US5501373 *Jul 30, 1992Mar 26, 1996R.G.S.A.S.Di Rosaria Galli & CAtomizing dispenser for endonasal drug spray administration
US5522804 *Apr 22, 1994Jun 4, 1996Lynn; Lawrence A.Aspiration, mixing, and injection syringe
US5531708 *Jul 1, 1994Jul 2, 1996American Cyanamid CompanySyringe for dispensing multiple dosages
US5549569 *Mar 30, 1995Aug 27, 1996Lawrence A. LynnFor the sequential/repetitive aspiration/injection of liquid and blood
US5613957 *Mar 11, 1994Mar 25, 1997Daniel PyApparatus for applying medicament to an eye
US5643218 *Aug 20, 1996Jul 1, 1997Lawrence A. LynnAuto-flushing medical fluid injection system
US5685869 *May 2, 1995Nov 11, 1997Daniel PyApparatus for applying medicament to an eye
US5697915 *May 30, 1996Dec 16, 1997Lynn; Lawrence A.Displacement-activated medical check valve
US5743886 *Aug 20, 1996Apr 28, 1998Lawrence A. LynnSequential medical fluid aspiration and injection system and method
US5769825 *Aug 20, 1996Jun 23, 1998Lynn; Lawrence A.Self-contained syringe and pharmaceutical packaging system for enclosed mixing of pharmaceutical and diluent
US5811061 *Jul 25, 1996Sep 22, 1998Baxter International Inc.Method and device for testing blood units for viral contamination
US5944702 *Sep 11, 1997Aug 31, 1999Instill & Co.Method for instilling a predetermined volume of medicament into an eye
US6228065Jun 22, 1998May 8, 2001Lawrence A. LynnDisplacement activated medical check valve
US6312413 *Oct 21, 1998Nov 6, 2001Novo Nordisk A/SCylinder ampoule
US6562007Sep 28, 2000May 13, 2003Bayer Healthcare LlcAdjustable dosage syringe
US6981963Mar 13, 2002Jan 3, 2006Mdc Investment Holdings, Inc.Pre-filled safety diluent injector
US7159490 *Mar 24, 2006Jan 9, 2007Ragan Philip JBottle injector
US7261704Dec 26, 2002Aug 28, 2007Terumo Kabushiki KaishaSyringe
US7427276Jul 20, 2007Sep 23, 2008Terumo Kabushiki KaishaSyringe
US7470259Mar 24, 2006Dec 30, 2008Hoyle Jr John DDosage control syringe
US7753890 *Jun 17, 2007Jul 13, 2010Dragon Drug Gun, Inc.Multiple drug injection apparatus
US7935086 *Dec 14, 2006May 3, 2011L M M Global Innovations, Inc.Multiple drug injection apparatus
US8021343 *Nov 9, 2007Sep 20, 2011Medical Components, Inc.Syringe for sequential expression of different liquids
US8021349Jan 29, 2010Sep 20, 2011Medical Components, Inc.Method of using a syringe
US8287491Nov 25, 2009Oct 16, 2012Becton, Dickinson And CompanySingle-use auto-disable syringe
US8771234Jul 6, 2011Jul 8, 2014Medical Components, Inc.Syringe for sequential expression of different liquids
US8771254Jul 12, 2011Jul 8, 2014Medical Components, Inc.Method of using a syringe
US20050215957 *Mar 26, 2004Sep 29, 2005Mallinckrodt Inc.Calibrated pushrod for injection volume control in prefilled syringes
US20120136334 *Jun 1, 2010May 31, 2012Sanofi-Aventis Deutschland GmbhDelivery of Two or More Medicaments Through a Single Dose Selection and Dispense Interface
USRE37047Dec 5, 1995Feb 6, 2001Daniel PyCartridge for applying medicament to an eye from a dispenser
DE2753609A1 *Dec 1, 1977Jan 4, 1979Silver JulesInjektionsspritze
EP0022987A1 *Jul 10, 1980Jan 28, 1981Cutter Laboratories, Inc.Syringe
EP0493639A1Dec 31, 1990Jul 8, 1992Jules Dr. SilverSyringe for dispensing measured quantities of a material
EP2094336A2 *Nov 9, 2007Sep 2, 2009Medical Components, Inc.Syringe for sequential expression of different liquids and method of using same
WO1981001104A1 *Oct 29, 1980Apr 30, 1981J SilverAdjustable dosage syringe
WO1999007421A1 *Aug 8, 1997Feb 18, 1999Mark L AndersonIncrementally adjustable dose syringe
WO2002026298A2Sep 24, 2001Apr 4, 2002Bayer AgAdjustable dosage syringe
WO2003057288A1 *Dec 26, 2002Jul 17, 2003Masaaki KasaiPre-filled syringe
WO2010139666A1 *Jun 1, 2010Dec 9, 2010Sanofi-Aventis Deutschland GmbhDelivery of two or more medicaments through a single dose selection and dispense interface
WO2010139669A1 *Jun 1, 2010Dec 9, 2010Sanofi-Aventis Deutschland GmbhMedicated module with premix medicament
WO2010139670A1 *Jun 1, 2010Dec 9, 2010Sanofi-Aventis Deutschland GmbhMedicated module for a drug delivery device
WO2011040900A1 *Nov 13, 2009Apr 7, 2011Salzman Marc JSyringe-attached topical anesthetic dispenser
WO2011117282A1 *Mar 23, 2011Sep 29, 2011Sanofi-Aventis Deutschland GmbhDedicated needle assembly
Classifications
U.S. Classification604/87, 604/211
International ClassificationA61M3/00, A61M5/315
Cooperative ClassificationA61M5/31551, A61M5/31596, A61M5/31561, A61M3/005, A61M5/31591
European ClassificationA61M5/315E2B1A, A61M5/315F3A, A61M5/315M, A61M3/00M
Legal Events
DateCodeEventDescription
Mar 13, 1981AS04License
Owner name: HARTFORD NATIONAL BANK AND TRUT COMPANY (A NATIONA
Owner name: SILVER INDUSTRIES, INC., ONE WISCONSIN AVE., NORWI
Effective date: 19801119
Mar 13, 1981AS06Security interest
Owner name: HARTFORD NATIONAL BANK AND TRUST COMPANY, 777 MAIN
Effective date: 19801119
Owner name: SILVER INDUSTRIES, INC., A CORP. OF CT.
Mar 13, 1981ASAssignment
Owner name: HARTFORD NATIONAL BANK AND TRUST COMPANY, 777 MAIN
Free format text: SECURITY INTEREST;ASSIGNOR:SILVER INDUSTRIES, INC., A CORP. OF CT.;REEL/FRAME:003844/0146
Owner name: SILVER INDUSTRIES, INC., ONE WISCONSIN AVE., NORWI
Free format text: LICENSE;ASSIGNOR:HARTFORD NATIONAL BANK AND TRUT COMPANY (A NATIONAL BANKING ASSOCIATION);REEL/FRAME:003844/0153
Effective date: 19801119
Sep 2, 1980AS02Assignment of assignor's interest
Owner name: SILVER INDUSTRIES, INC., ONE WISCONSIN AVE.,NORWIC
Owner name: SILVER, JULES
Effective date: 19800609