|Publication number||US3583399 A|
|Publication date||Jun 8, 1971|
|Filing date||Aug 29, 1969|
|Priority date||Sep 3, 1968|
|Also published as||CA873458A|
|Publication number||US 3583399 A, US 3583399A, US-A-3583399, US3583399 A, US3583399A|
|Inventors||Anthony F Ritsky|
|Original Assignee||Astra Chem Ltd|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (11), Referenced by (90), Classifications (13)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent H 13,ss3,399
 Inventor Anthony F. Ritsky 2,660,168 11/1953 Pontius ..(128/218PUX) Clarkson, Ontario, Canada 2,798,487 7/1957 Ferguson..... 128/218P  App1.No. 854,054 3,295,525 1/1967 Evers et a1. 128/218PX  Filed Aug. 29, 1969 3,368,558 2/1968 Sarnoff 128/218D Patented June 8,  Assignee Astra Chemicals Ltd.
453011 11/1948 Canada M dd ta issauga On no Canada 59,880 2/1954 France 1,508,686 11/1967 France 54 SELF-ASPIRATING SYRINGE Primary Examinerlos eph Reich 10 Claims, 6 Drawing Figs. Alwrney$mart and Bigger  US. Cl 128/218D,
l23/218? 128/22l 128/272 ABSTRACT: A hypodermic syringe for medical, dental, or (51] Int. Cl A6lm 5/24, veterinary use employing cartridge ampuls f injectable fl id 1 1/06 arranged to be automatically self-aspirating. A resilient mem- [501 Field of Search 128/218 R, brane is d fl t d at the f d end f the ampul rearwardly Z 21 218 D, P, 221, 272 of the ampul each time the syringe plunger is actuated, so that upon release of the plunger the membrane is automatically  References cued resiliently restored to its normal position thereby producing UNITED STATES PATENTS conditions of reduced pressure or aspiration within the ampul. 1,712,070 5/1929 Cressler 128/218D The membrane is deflected on a stud positioned at the forward 1,798,117 3/1931 Brockway.... 128/22 1 X end of the ampul-receiving cavity in the syringe, or on a mova- 2,020,828 11/1935 Goldberg..... 128/272X ble flanged tubular element on'the ampul adjacent the mem- 2,244,969 6/1941 Smith 128/218D brane and projecting forwardly of the ampul.
IO l6 PATENTED JUN 8197! INVENTOR THONY ERITSKY ATTORNEYS.
SELF-ASPIRATING SYRINGE BACKGROUN D OF THE INVENTION This invention relates to improvements in hypodermic syringes and in particular to a new or improved self-aspirating syringe. Aspiration" is the procedure whereby an operator in making an injection determines whether or not the needle is in a proper position for injecting to prevent inadvertent deposition of injection solution directly into a blood vessel which could cause untoward patient reaction. After the needle has been inserted in the area to be injected, the syringe is manipu' lated to create a reduced pressure within the fluid to be injeeted whereby if the needle is uncorrectly positioned, blood from the area to be injected is drawn back through the hypodermic needle into the syringe where it can be observed by the operator.
DESCRIPTION OF THE PRIOR ART In the medical, dental and veterinary fields cartridge am puls of injectable fluid are now commonly used in hypodermic syr inges. Such ampuls usually comprise a cylindrical container of glass or clear plastics material, the forward end of which is sealed by a rubber membrane and the rear end of which is sealed by a rubber piston which is slidable within the body of the container. In use such cartridge ampuls are positioned within the barrel of a syringe so that the membrane is pierced by the rear end of the needle and the rubber piston is ad vanced by a thumb-operated plunger to inject the fluid. Where such a syringe is required to be capable of aspiration, it has generally been found necessary to form the syringe plunger with a pointed tip having barbs or flukes so that when the plunger is pressed forward to engage the piston of the ampul, the barbs or flukes bite into the material of the piston so that the piston can be drawn rearward slightly by the plunger to create conditions of aspiration within the ampul.
SUMMARY OF THE INVENTION According to the present invention there is provided a selfaspirating syringe adapted for use with a plunger-type cartridge ampul of the type comprising a tubular body filled with injectable fluid closed at one end by a movable piston member and at the other end by a flexible membrane, said syringe comprising: a body member having a cavity adapted to accommodate therewithin one of said cartridge ampuls, and having axially disposed openings at the front and rear ends thereof; a plunger member extending through the opening at the rear end of said cavity and slidable with respect thereto, said plunger having a head at its forward end adapted to engage the said movable piston member to slide the same forwardly within said tubular body, and a thumb piece or palm rest at the rear end thereof for pressing said plunger forward; a adapter within the opening at the front end of the syringe body member arranged to receive and secure hypodermic needle in axial alignment with said tubular body with the rear end of the needle extending through said flexible membrane into said injectable solution; and stud means at the front end of said cavity projecting rearwardly thereof and adapted to engate said membrane whereby upon movement forward of said tubular body under the influence of said plunger, said membrane is stretched rearwardly of said tubular body, and upon release of said influence said tubular body moves rearwards under the influence of said stretched membrane to create conditions of aspiration within said tubular body.
With this arrangement, conditions of aspiration are created within the ampul each time the plunger is released.
Preferably the plunger is guided within a bushing in the opening in the rear end of the body member, the bushing itself being movable axially of the opening and being resilient urged in a forwards direction to engage the rear end of the cartridge ampul. Preferably, the rear end of the bushing carries a flange to the rear of the syringe body whereby the bushing can be manually engaged and moved axially to cause aspiration of the syringe without movement of the plunger. The stud means may comprise a central rearwardly projecting stud integral with the adapter or alternatively may comprise a collar on the hypodermic needle itself arranged to seat against the rear face of the adapter when the needle is secured therein.
From another aspect, the invention provides a plunger-type cartridge ampul comprising a generally tubular container having a rear end sealed by a piston which is movable axially of the container, and a front end sealed by a resilient membrane associated with which is a central forwardly projecting element which is capable of transmitting to the membrane a deflection inwards of the front end of the container. The forwardly projecting element associated with the membrane performs the same function as the stud means referred to above in the aspiration of the syringe.
BRIEF DESCRIPTION OF THE DRAWINGS The invention will further be described with reference to the accompanying drawings wherein:
FIG. I is a perspective view of a plunger-type cartridge am- P FIG. 2 is a longitudinal sectional view of a self-aspirating hypodermic syringe according to the invention;
FIG. 3 and 4 are fragmentary sectional views to a larger scale illustrating details of the operation of the syringe of FIG.
FIG. 5 is a fragmentary sectional view showing a modified syringe;and
FIG. 6 is a fragmentary longitudinal sectional view of a modified cartridge ampul according to the invention.
DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 illustrates a cartridge ampul 10 of known kind which comprises a container defined by generally cylindrical glass wall sealed at one end by a rubber piston 11 and at the other end by a rubber membrane 12. The injectable fluid is sealed in the container between the piston 11 and membrane 12. The membrane is secured against the end of the container by an annular sheet metal collar 13, one end of which is spun or crimped into a depression 14 in the surface of the container and the other end of which carries an inwardly projecting radial flange 15 which overlies the peripheral area of the membrane and presses it against the end of the container.
The syringe generally indicated at 16 in FIG. 2, comprises a cylindrical barrel [7 defining a cavity 18 to receive a cartridge ampul 10. As is common practice, the barrel 17 is formed with a large axially extending aperture (not shown) in its wall to permit insertion and removal of the ampul. The forward end of the barrel is secured to a fitting I9 formed with a central axially directed screw-threaded opening 20. An adapter 21 in threaded engagement with the opening 20 is formed with a central stud 22 which projects rearwardly into the cavity 18. The front end of the adapter 21 is formed with a spigot 23 which is in threaded engagement with a hub 24 which carries an axially extending hypodermic needle 25. The needle 25 extends rearwardly from the hub through an axial bore 26 in the adapter and in the stud 22 and extends into the cavity 18 beyond the stud 22.
The rear end of the barrel I7 is received in a fitting 27 which carries a pair of laterally extending finger grips 28. A sleeve 29 in threaded engagement with the fitting 27 carries at its rear end a gland 30 having a radial flange 31. The gland 30 extends forwardly within the sleeve 29 and its inner surface forms a smooth cylindrical continuation of the inner surface of the barrel 17. A bushing 32, which extends through an axial hole in the gland 30, has a flanged head 33 which is guided for reciprocating movement by the cylindrical inner surface of the gland. The rear end of the bushing 32 carries a radially extending flange 34 secured thereto by a retaining clip 35. The bushing is surrounded within the gland 30 by a compression spring 36 acting between the flanged head 33 and the end wall of the gland 30 and urging the bushing in a forward direction.
The bushing is preferably of a low friction material such as nylon and is formed with a central bore within which is slidably received a plunger 37. The forward end of the plunger carries a head 38 adapted to engage the rubber piston of an ampul 10. The plunger 37 may be pressed forward by means of a thumb plate 39 carried on the rear end thereof. In the retracted position of the plunger 37, the head 38 is received in a recess 40 in the forward end of the flanged head of the bushing 32.
To load a cartridge ampul into the syringe 16, the plunger 37 is withdrawn rearwardly and the ampul is inserted through the aperture in the barrel 17, plunger end firstv The plunger is thereafter released and the bushing 32 is advanced under the force of the compression spring 36 until the flanged head thereof engages the end of the cylindrical wall of the ampul. This movement forces the ampul 10 forward so that the membrane 12 of the ampul is pierced by the rear end of the hypodermic needle 25. In this position the end of the stud 22 at the forward end of the cavity 18 rests against the membrane 12 but the strength of the spring 36 is chosen such that this engagement does not cause any appreciable deflection of the membrane.
Subsequent forward pressure applied to the thumb plate 39 forces the ampul ll forwards until the flange 15 of the collar 13 engages the end face of the adapter 21 as shown in FIG. 3. In reaching this position, the membrane 12 is deflected by the stud 22 as shown in the Figure. Forward pressure applied to the thumb plate 39 will now cause the piston 11 to be advanced within the ampul 10 so that the fluid from the ampul is ejected through the needle 25. Upon release of the thumb plate 39, the syringe is automatically aspirated by the resilient action of the membrane 12 which restores to its normal position as indicated in FIG. 4 thus causing conditions of reduced pressure within the ampul 10. Aspiration can also be effected by pressing forward and releasing the flange 34 of the bushing 32 as indicated by the arrows in FIG. 2. The piston II is adapted to engage the internal wall of the ampul 10 with sufficient friction to enable the head 38 to cause the membrane 12 to be flexed as shown in FIGS. 3 and 4, and also to permit the ejection of the contents of the ampul when and as desired.
An alternative arrangement is shown in FIG. wherein an adapter 210, also constitutes a hub to secure a hypodermic needle 25a in the forward end of the syringe. In this case the stud means is formed not on the adapter but as a collar 41 on the needle 25a itself. As shown, the collar 41 is positioned to the rear of the adapter 210 and performs a function similar to that of the stud 22 in the embodiment of FIGS. 2 to 4.
Alternatively, the stud means instead of being associated with the syringe or with the needle can be formed as an integral part of the ampul. Thus, as shown in FIG. 6, an ampul b, generally similar to the one illustrated in FIG. 1, has an aspirating element 42 positioned between the collar 13!) and the membrane 121;. The element 42 comprises an outwardly extending radial flange 43 positioned between the radial flange b of the collar 13b and the membrane 12b and a forwardly extending tubular portion 44 extending from the front end of the ampul. It will be apparent that the ampul 10b, when fitted in a syringe 16 of the type shown in FIG. 2, the adapter of which does not have the stud 22, will perform the same aspirating function as the stud 22 or as the collar 41 in the em bodiment shown in FIG. 5.
1. A self-aspirating syringe for use with a plunger-type cartridge ampul of the type comprising a tubular body filled with injectable filled fluid having a rear end closed by a movable piston member and a forward end closed by a flexible resilient membrane, said syringe comprising: a body member having means providing a cavity to accommodate therewithin one of said cartridge ampules, and having axially disposed openings at the front and rear ends thereof; a plunger member extending through the opening at the rear end of said cavity and slidable with respect thereto, said plunger having a head at its forward end adapted to engage the said movable piston member to slide the same forwardly within said tubular body, and a manually engageable actuator at the rear end thereof for pressing said plunger forward; means for mounting an adapter within the opening at the front end of the syringe body member, said adapter being arranged to receive and secure a hypodermic needle in axial alignment with said tubular body with the rear end of the needle extending through said flexible membrane into said injectable solution; and stud means adjacent to the front end of said body, projecting rearwardly therewithin and adapted to be engaged by said membrane whereby upon movement forward by of said tubular body under the influence of said plunger said membrane is stretched rearwardly of said tubular body, and upon release of said influence said tubular body moves rearwards under the influence of said stretched membrane to create conditions of aspiration within said tubular body.
2. A self-aspirating syringe according to claim 1 wherein said plunger member is guided to slide within a bushing carried within said opening at the rear end of the body member, said bushing having a front end adapted to extend within the rear end of the tubular body of the cartridge ampul, said bushing extending rearwardly through said opening at the rear end of said body member and being axially slidable therein, and wherein resilient means engaging said bushing are adapted controllably to bias said bushing in a forward direction.
3. A self-aspirating syringe according to claim 2 wherein said bushing carries a flange at the rear of the syringe body member by means of which the bushing can be engaged and moved axially to urge said cartridge ampul forward; whereby said membrane is stretched inwardly of said tubular body and upon release of said bushing the tubular body moves rearwards under the influence of said stretched membrane to create conditions for aspiration within said tubular body.
4. A self-aspirating syringe according to claim 2 wherein said resilient means comprises a compression spring surrounding a length of the bushing between a flange at the forward end thereof and the rear end of said body member.
5. A self-aspirating syringe according to claim 2 wherein the plunger has a head at the forward end thereof and the forward end of the bushing is formed with an enlarged recess of a size to accommodate the head of said plunger.
6. A self-aspirating syringe according to claim 1 wherein said stud means comprises a central rearwardly projecting stud integral with said adapter.
7. A self-aspirating syringe according to claim 1 wherein said stud means comprises a collar on said hypodermic needle arranged to seat against the rear face of the adapter when the needle is secured therein.
8. A plunger-type cartridge ampul for use in a hypodermic syringe comprising a generally tubular container having a rear end sealed by a piston which is movable axially of the container, and a front end sealed by a resilient membrane, the cartridge having a central forwardly projecting element at the forward end thereof which in use is operative to transmit to the membrane a deflection rearwardly of the front end of the container.
9. A plunger-type cartridge ampul according to claim 8 wherein said membrane is secured to the front end of the container by an annular collar which has a radial inwardly-projecting flange which overlies the peripheral area of said membrane, said element comprising a short tubular member extending forwardly from the membrane and having a radial outwardly extending flange retained between the membrane and the collar flange.
10. A self-aspirating syringe comprising a generally tubular body having a cavity and an open rear end and a plunger-type cartridge ampul received in said syringe body and comprising a tubular body filled with injectable fluid and having a rear end closed by a movable piston member and a forward end closed by a flexible resilient membrane, the syringe having an axially disposed plunger extending through the opening in the rear end thereof and into the cavity and being axially movable said plunger having a forward end having a head operative to and engaging said membrane, said abutment means being operative, upon forward movement of said ampul in said cavity under the influence of said plunger, to stretch said membrane rearwardly of said tubular body, whereby upon release of said influence said stretched membrane is operative to move said tubular body rearwardly to create conditions of aspiration within said ampul.
UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION Patent 3,583,399 Dated une 8, 197i Inventor(s) Anthony F. Ritsky It is certified that error appears in the above-identified patent and that said Letters Patent are hereby corrected as shown below:
In the heading below the last line thereof, insert --C1aims priority, Canadian application Serial No. 29,115, filed September 3, 1968-- Signed and sealed this 2 +th day of April 1973.
EDI-YARD M. FLETCHER, J'R. ROBERT GOTTSCHALK Attesting Officer Commissioner of Patents FORM po'mso H069) USCOMM-DC eos'ls-pe W U Sv GOVERNMENT PRINTING OFFICE r 969 O-366-33l
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1712070 *||Jan 30, 1924||May 7, 1929||Cook Lab Inc||Syringe|
|US1798117 *||May 2, 1930||Mar 24, 1931||Macgregor Instr Company||Syringe|
|US2020828 *||Jun 12, 1933||Nov 12, 1935||Novocol Chemical Mfg Co Inc||Hypodermic syringe and closure cap for containers|
|US2244969 *||May 20, 1940||Jun 10, 1941||Arthur E Smith||Ampoule syringe|
|US2660168 *||Jul 10, 1951||Nov 24, 1953||Hoechst Ag||Syringe casing and stoppered cylindrical ampoule for direct injection|
|US2798487 *||May 9, 1952||Jul 9, 1957||Becton Dickinson Co||Syringe assembly|
|US3295525 *||Apr 7, 1964||Jan 3, 1967||Astra Apotekarnes Kem Fab||Self-aspirating cartridge ampoule|
|US3368558 *||Aug 21, 1964||Feb 13, 1968||Sarnoff||Two compartment cartridge|
|CA453011A *||Nov 30, 1948||Mizzy||Hypodermic syringe|
|FR59880E *||Title not available|
|FR1508686A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3797487 *||Oct 27, 1971||Mar 19, 1974||Woelm Fa M||Hypodermic syringe with clutch for aspiration|
|US3809298 *||Jul 18, 1973||May 7, 1974||Precision Sampling Corp||Syringe|
|US3878846 *||Nov 22, 1972||Apr 22, 1975||Spad Lab||Hypodermic syringe with parts disposable after use|
|US3977402 *||Jul 14, 1975||Aug 31, 1976||William Floyd Pike||Injection apparatus and method with automatic aspiration feature|
|US3990446 *||Feb 18, 1975||Nov 9, 1976||Jewel Dean Randolph Taylor||Hypodermic syringe for stabilized aspiration by one hand|
|US4216771 *||Dec 5, 1977||Aug 12, 1980||Sven Arlers||Hypodermic syringe with aspiration effect|
|US4333456 *||Feb 9, 1981||Jun 8, 1982||Sterling Drug Inc.||Self-aspirating hypodermic syringe and self-aspirating assembly therefor|
|US4333457 *||Feb 9, 1981||Jun 8, 1982||Sterling Drug Inc.||Self-aspirating syringe with frictionally engaged locking collet|
|US4381779 *||Jul 16, 1981||May 3, 1983||Sterling Drug Inc.||Deformable slidable piston to provide self-aspiration in hypodermic cartridge ampoules|
|US4407283 *||Oct 19, 1981||Oct 4, 1983||Dale C. Grier||Self-injecting syringe|
|US4540405 *||Jul 12, 1983||Sep 10, 1985||Cilco, Inc.||Disposable syringe sleeve|
|US4744791 *||Dec 18, 1986||May 17, 1988||Georges Egolf||Syringe with automatic piston retraction|
|US4883472 *||Jul 31, 1987||Nov 28, 1989||Disetronic Ag.||Injection device|
|US5232457 *||Aug 5, 1991||Aug 3, 1993||Grim John P||Medical syringe|
|US5505704 *||Jun 1, 1995||Apr 9, 1996||Eli Lilly And Company||Manifold medication injection apparatus and method|
|US5536249 *||Mar 9, 1994||Jul 16, 1996||Visionary Medical Products, Inc.||Pen-type injector with a microprocessor and blood characteristic monitor|
|US5584815 *||Apr 19, 1995||Dec 17, 1996||Eli Lilly And Company||Multi-cartridge medication injection device|
|US5593390 *||Feb 28, 1995||Jan 14, 1997||Visionary Medical Products, Inc.||Medication delivery device with a microprocessor and characteristic monitor|
|US5728074 *||Dec 5, 1994||Mar 17, 1998||Visionary Medical Products, Inc.||Pen-type injector with a microprocessor and blood characteristic monitor|
|US5820602 *||Sep 5, 1996||Oct 13, 1998||Visionary Medical Products, Inc.||Pen-type injector drive mechanism|
|US5876379 *||Jan 22, 1998||Mar 2, 1999||Alcon Laboratories, Inc.||Syringe cannula holder|
|US5925021 *||Jul 24, 1997||Jul 20, 1999||Visionary Medical Products, Inc.||Medication delivery device with a microprocessor and characteristic monitor|
|US5925032 *||Feb 17, 1998||Jul 20, 1999||Alcon Laboratories, Inc.||Syringe cannula holder|
|US5989226 *||Nov 10, 1994||Nov 23, 1999||Seldoren Limited||Syringe with detachable drug housing|
|US6086569 *||May 4, 1999||Jul 11, 2000||Schweizer; Kenneth M.||Hypodermic syringe|
|US6158862 *||Dec 4, 1997||Dec 12, 2000||Alcon Laboratories, Inc.||Method of reducing glare associated with multifocal ophthalmic lenses|
|US6416323||May 11, 2000||Jul 9, 2002||Safety Syringes, Inc.||Aspirating dental syringe with needle shield|
|US6500239||Mar 14, 2001||Dec 31, 2002||Penjet Corporation||System and method for removing dissolved gas from a solution|
|US6613010||Apr 13, 2001||Sep 2, 2003||Penjet Corporation||Modular gas-pressured needle-less injector|
|US6613011||Mar 15, 2002||Sep 2, 2003||Penjet Corporation||Gas-pressured engine with valve|
|US6755220||Apr 25, 2002||Jun 29, 2004||Penjet Corporation||Method and apparatus for filling or refilling a needle-less injector|
|US6824526||Oct 22, 2001||Nov 30, 2004||Penjet Corporation||Engine and diffuser for use with a needle-less injector|
|US7018356||Oct 31, 2002||Mar 28, 2006||Wise Roger R||Method and apparatus for adjusting the contents of a needle-less injector|
|US7601140||Oct 13, 2009||Alcon, Inc.||Syringe pressure applicator|
|US8007491||Sep 19, 2008||Aug 30, 2011||The Board Of Trustees Of The Leland Stanford Junior University||Methods for application of reduced pressure therapy|
|US8100865 *||Jun 14, 2001||Jan 24, 2012||Hambley Limited||Hypodermic syringe with passive aspiration feature|
|US8128607||Apr 14, 2010||Mar 6, 2012||Spiracur Inc.||Devices and methods for treatment of damaged tissue|
|US8177764||Feb 17, 2009||May 15, 2012||Spiracur Inc.||Devices and methods for treatment of damaged tissue|
|US8246590||Oct 10, 2008||Aug 21, 2012||Spiracur, Inc.||Closed incision negative pressure wound therapy device and methods of use|
|US8257324 *||May 21, 2007||Sep 4, 2012||Georgia Tech Research Corporation||Microneedle drug delivery device|
|US8337474||Dec 25, 2012||Spiracur Inc.||Devices and methods for treatment of damaged tissue|
|US8361043||Jan 29, 2013||Spiracur Inc.||Reduced pressure therapy of the sacral region|
|US8366693||Jun 18, 2010||Feb 5, 2013||Spiracur, Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US8372044||Feb 12, 2013||Safety Syringes, Inc.||Syringe with needle guard injection device|
|US8398604||Mar 19, 2013||Spiracur, Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US8409159||Apr 9, 2010||Apr 2, 2013||Spiracur, Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US8435221||Jun 18, 2010||May 7, 2013||Spiracur, Inc.||Closed incision negative pressure wound therapy device and methods of use|
|US8444614||May 21, 2013||Spiracur, Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US8529532||Sep 26, 2011||Sep 10, 2013||The Board Of Trustees Of The Leland Stanford Junior University||Reduced pressure therapy devices|
|US8562576||Jan 11, 2011||Oct 22, 2013||Spiracur, Inc.||Closed incision negative pressure wound therapy device and methods of use|
|US8708966||Aug 9, 2010||Apr 29, 2014||Georgia Tech Research Corporation||Microneedle devices and methods of manufacture and use thereof|
|US8728045||Mar 4, 2010||May 20, 2014||Spiracur Inc.||Devices and methods to apply alternating level of reduced pressure to tissue|
|US8728046||Sep 26, 2011||May 20, 2014||Spiracur Inc.||Controlled negative pressure apparatus and alarm mechanism|
|US8753322||Aug 10, 2011||Jun 17, 2014||Spiracur Inc.||Controlled negative pressure apparatus and alarm mechanism|
|US8795246||Jul 1, 2011||Aug 5, 2014||Spiracur Inc.||Alarm system|
|US8834434||Oct 18, 2013||Sep 16, 2014||Spiracur Inc.||Closed incision negative pressure wound therapy device and methods of use|
|US8858516||Sep 26, 2011||Oct 14, 2014||Spiracur Inc.||Controlled negative pressure apparatus and absorbency mechanism|
|US8926575||Sep 13, 2012||Jan 6, 2015||Spiracur Inc.||Devices and methods for treatment of damaged tissue|
|US8961481||Feb 3, 2011||Feb 24, 2015||Spiracur Inc.||Devices and methods for treatment of damaged tissue|
|US9044234||Mar 1, 2013||Jun 2, 2015||Spiracur Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US9067023||Nov 14, 2012||Jun 30, 2015||University Of Louisville Research Foundation, Inc.||Ergonomic syringe and adaptor|
|US9259358||Jan 28, 2013||Feb 16, 2016||Kci Licensing, Inc.||Reduced pressure therapy of the sacral region|
|US9283307||Mar 31, 2011||Mar 15, 2016||Kci Licensing, Inc.||Devices and methods for treatment of damaged tissue|
|US9302903||Dec 14, 2001||Apr 5, 2016||Georgia Tech Research Corporation||Microneedle devices and production thereof|
|US9345822||Feb 27, 2013||May 24, 2016||Kci Licensing, Inc.||Methods and devices for applying closed incision negative pressure wound therapy|
|US20020082543 *||Dec 14, 2001||Jun 27, 2002||Jung-Hwan Park||Microneedle devices and production thereof|
|US20030187406 *||Jun 14, 2001||Oct 2, 2003||Spofforth Leonard Morris||Hypodermic syringe with passive aspiration feature|
|US20050192530 *||Jun 2, 2004||Sep 1, 2005||Penjet Corporation||Method and apparatus for needle-less injection with a degassed fluid|
|US20050288625 *||Jun 25, 2004||Dec 29, 2005||Rossback Richard A||Syringe pressure applicator|
|US20070225676 *||May 21, 2007||Sep 27, 2007||Prausnitz Mark R||Microneedle drug delivery device|
|US20090012482 *||Mar 13, 2008||Jan 8, 2009||Pinto Moshe||Devices and methods for application of reduced pressure therapy|
|US20090076467 *||Sep 19, 2008||Mar 19, 2009||Pinto Moshe||Methods for application of reduced pressure therapy|
|US20090259203 *||Oct 10, 2008||Oct 15, 2009||Dean Hu||Closed incision negative pressure wound therapy device and methods of use|
|US20100042021 *||Feb 18, 2010||Spiracur, Inc.||Devices and methods for treatment of damaged tissue|
|US20100137775 *||Nov 25, 2009||Jun 3, 2010||Spiracur Inc.||Device for delivery of reduced pressure to body surfaces|
|US20100160901 *||Dec 23, 2009||Jun 24, 2010||Dean Hu||Device for delivery of reduced pressure to body surfaces|
|US20100174250 *||Jul 8, 2010||Spiracur Inc.||Reduced pressure therapy of the sacral region|
|US20100198173 *||Aug 5, 2010||Spiracur, Inc.||Devices and methods for treatment of damaged tissue|
|US20100198174 *||Aug 5, 2010||Spiracur, Inc.||Devices and methods for treatment of damaged tissue|
|US20100228205 *||Mar 4, 2010||Sep 9, 2010||Spiracur Inc.||Devices and methods to apply alternating level of reduced pressure to tissue|
|US20100312191 *||Dec 9, 2010||Georgia Tech Research Corporation||Microneedle Devices and Methods of Manufacture and Use Thereof|
|US20110015594 *||Jun 18, 2010||Jan 20, 2011||Dean Hu||Methods and Devices for Applying Closed Incision Negative Pressure Wound Therapy|
|US20110105963 *||May 5, 2011||Spiracur, Inc.||Closed incision negative pressure wound therapy device and methods of use|
|US20110106026 *||May 5, 2011||Kenneth Wu||Methods and devices for applying closed incision negative pressure wound therapy|
|US20110130691 *||Jun 2, 2011||Dean Hu||Devices and methods for treatment of damaged tissue|
|US20110137270 *||Jun 9, 2011||Dean Hu||Pressure indicator|
|EP0160711A1 *||May 3, 1984||Nov 13, 1985||BŁnder Glas GmbH||Injection syringe|
|WO1997040875A2||May 1, 1997||Nov 6, 1997||Stan Janus||Improved drug injection system with self-aspiration feature|
|WO1997040875A3 *||May 1, 1997||Mar 19, 1998||Stan Janus||Improved drug injection system with self-aspiration feature|
|WO2001085237A2||May 2, 2001||Nov 15, 2001||Safety Syringes, Inc.||Aspirating dental syringe with needle shield|
|U.S. Classification||604/232, 604/900|
|International Classification||A61M5/24, A61M5/31|
|Cooperative Classification||A61M2005/2414, A61M2005/3112, Y10S604/90, A61M2005/247, A61M5/3148, A61M2005/2437, A61M5/24, A61M2005/2477|