|Publication number||US3592184 A|
|Publication date||Jul 13, 1971|
|Filing date||Dec 16, 1969|
|Priority date||Dec 16, 1969|
|Publication number||US 3592184 A, US 3592184A, US-A-3592184, US3592184 A, US3592184A|
|Inventors||Erwin J Klink, David H Watkins|
|Original Assignee||David H Watkins, Erwin J Klink|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (6), Referenced by (110), Classifications (14)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent inventors David ll. Watkins 6039 N. Waterbury Road, Des Moinee, Iowa 50312; Erwin J. Klink, 814 Laurel Circle S.E., Alilquerqne, N. Mex. 87108 Appl No 885,507
Filed Dee. I6, 1969 Patented July [3, i971 HEART ASSIST METHOD AND CATHETER 5 Chi-54 Drawing Figs.
US. CL 128/1 R, I28/245, 128/348 Int. Cl. A61n1 1/03, A6ib l9/OO fieltlolsenrch l28/l R,
2l4, 348, 24l,245, 344; 3/l
 References Cited UNITED STATES PATENTS 3,071,137 l/l963 Niebel et al 128/348 X 3,266,487 8/1966 Watkins et al. 128/] R 3,426,743 2/i969 Chesnut et al. I 28/1 R 3,472,230 10/1969 Fogarty v a v a 128/345 3,504,662 4/1970 Jones i28/l R 3,516,410 6/1970 Hakim l28/245 X Primary Examiner- Dalton L. Truluck Anonleylohn Howard Joynt ABSTRACT: Method and device for augmenting the action of an ailing heart having an incompetent aortic valve, wherein blood is sucked up from the aorta, while blocking flow to the arterial tree, and then, upon reverse, a major portion of the blood is forced into the arterial tree and a minor portion forced into the coronary arteries of the heart itself.
PATENTEI] JUL 1 3H]?! 3, 592, l 84 SHEET 1 0F 2 INVENTORS David h! Watkins Enw' J link BY .fl
ATTORNEY PATENIED JUL 1 3 an SHEET 2 BF 2 m S w W m m a 1 WM A HJ V m w 3 m HEART ASSIST METHOD AND CATHETER As a matterof introduction, our invention relates to method and apparatus for augmenting the action of the ailing heart of a patient.
Among the objects of our invention is the provision of a method and a device for safely, effectively and reliably moving blood from the incompetent aortic valve of a failing heart and then discharging the same into the arterial tree while supplying a minor portion of the blood to the coronary arteries of the heart itself.
Other objects in part will be apparent and in part particularly pointed to in the description which follows.
Our invention may be considered to reside in the combination of elements, features of construction and arrangement of parts and in the several operational steps and the relation of each of the same to one or more of the others, all as described herein and set out in the claims at the end of this specification.
CROSS-REFERENCE TO RELATED APPLICATION The present application for patent is generally related to our application of May 27, I969, Ser. No. 828,151 entitled Heart Assist Method and Apparatus.
BACKGROUND OF THE INVENTION In order to gain a better understanding of certain features of our invention, it is to be noted at this point that situations occur wherein the heart action of the patient is wholly insuffi cient to supply the bodily needs. In certain of these instances the patient has an incompetent aortic valve. And blood pumped out of the left ventricle of the heart partially flows back into the left ventricle, this as a result of the inability of the aortic valve to prevent the back flow. As a result, there is a loss of pressure, and a loss of blood supplied the arterial tree. Moreover, in many instances there is insufficient blood supplied the coronary arteries of the heart itself.
Although many efforts have been made in the past to overcome the deficiencies of an ailing heart, and indeed to take ac.- count of an incompetent aortic valve, for one reason or another these have not been entirely satisfactory. In some instances prior systems and apparatus have been too complicated. In others they have been either too costly or not sufficiently reliable for most use.
An object of the present invention, therefore, is to provide a system, as well as a method and device, for overcoming the deficiencies of the prior art and assure effective movement of blood from an incompetent aortic valve of the heart and discharge a major portion of the same into the arterial tree while at the same time supplying a minor portion to the coronary arteries.
SUMMARY OF THE INVENTION Directing attention to the practice of our invention, we provide a method and device of novel construction. A catheter is introduced into the aorta, or into the left subclavian artery, by means of an arterialotomy incision. The proximate end of the catheter of course protrudes from the artery and is provided with a plastic tube connecting to a reciprocating pump and apparatus of the character more generally shown and described in our copending application for patent identified above. The distal end of the catheter is directed toward the heart. It is this end of the catheter which is provided with one hole or port. Back from this first opening there is provided a further hole or port. An expandible membrane is located circumferentially and radially extending about the catheter at a position between the two holes or ports referred to.
BRIEF DESCRIPTION OF THE DRAWINGS In the accompanying drawings in which we disclose two preferred embodiments of our invention:
FIG. I is the catheter of our invention on a somewhat enlarged scale;
FIG. 2 is a sectional view of the catheter of FIG. I as installed in the aorta of a patient at a position adjacent to the aortic valve;
FIG. 3 is a detached view ofa portion of the catheter of FIG. 1 on enlarged scale in order to best illustrate certain features of the invention; and
FIG. 4 is a similar sectional view on an enlarged scale of an alternate embodiment of the catheter of our invention.
Like reference characters denote like parts throughout the several views of the drawings.
DESCRIPTION OF THE PREFERRED EMEODIM ENTS Turning now to a preferred embodiment of our invention, attention is directed to FIGS. 1, 2 and 3 of the drawings. It is seen that our catheter essentially comprises a hollow shaft portion with proximate end 500 received and secured in tube 29 leading to a suitable blood pump (not shown). The distal end of the catheter is provided with a suitable port or opening 54 just back from tip 50b (see FIG. The the distal end, moreover, is provided with a further port 55 back from port 54. Surrounding the catheter at a point between the ports 54 and 55 there is an expansible imperforate membrane 52 serving as valve means exteriorly of said catheter. This is suitably secured to catheter 50 and flares outwardly and circumferentially about the same. The outer circumferential extremity of the flaring membrane is secured to catheter shaft 50 by suitable radial filaments SI.
During the cyclic operation of the blood pump associated with our device, and connecting to the catheter by way of tube 29 as indicated above, with the suction stroke of the pump the blood coming from the aortic valve enters port 54. In this action a membrane valve means 56 secured to the inner walls of the catheter adjacent the distal end thereofcollapses inwardly. Such action permits the free flow of blood into the catheter and to the pump. During this action any loss of blood through the second port 55 is prevented by virtue of the collapse of the exteriorly mounted membrane valve means 57 (see FIG. 3) against the outer wall of the catheter. And any inflow of blood from the arterial tree toward the distal end of the catheter and into port 54 is prevented by the expansion of circumferential membrane 52. Membrane 52 also serves to prevent any collapse of the walls of the aorta under the reduced pressure conditions obtaining during this cycle in the pump.
With a reverse of pump action, that is, the discharge stroke, blood flows back into the catheter by way of tube 29 and out through port 55 into the aorta. During this action the exteriorly positioned membrane 57 is expanded outwardly under the pressure of the blood and allows an unimpeded flow into the arterial tree.
It will be noted that port 54 adjacent to the distal end of the catheter is not completely closed by the interiorly positioned membrane 56. The construction is such that there is provided a portion 54a that amounts roughly to some one-third the area of the entire port 54. As a result, a substantial portion of the blood coming from the pump with the discharge stroke passes into the aorta near its distal end, this by way of port 540, and effectively supplies the coronary arteries of the heart itself. While provision is made for sufficient blood to flow into the coronary arteries, there is no undue reverse filling of the incompetent left ventricle.
A modified catheter construction is shown in FIG. 4 of the drawings. In this the distal end of the catheter is provided with a reciprocable sleeve 58, with valve means comprising closed end 60 and port 59. A lug 61 provided on sleeve 58 rides back and forth in slot 50'0 provided in the catheter wall. With the pressure stroke of the pump, movement of sleeve 58 to the left, as seen in FIG. 4, is arrested by lug 61 striking one end of slot 50'a, and with the suction stroke the reverse movement is arrested by the lug striking the other end of the slot.
During the suction stroke of the pump, sleeve 58 is drawn to the right. With this movement the walls of sleeve 58 effectively close port 55' of the catheter. And concurrently with this action, port 59 of sleeve 58 is brought into register with port 54' of the catheter. Blood from the aorta then is sucked into catheter 50' by way of registered ports 54' and 59. Any flow of blood from the arterial tree under the back pressure of the tree and the suction conditions maintaining in the area of the aorta is prevented by the outward expansion of membrane valve 52.
With the reverse stroke of the pump during the discharge cycle of the same, the reciprocable sleeve 58 is forced outwardly or to the left, as seen in the drawing, under the pressure conditions then maintaining. This provides free access of the blood to port 55' and thence to the arterial tree. Under the pressure action port 59 is brought forward from register with port 54' and extends somewhat beyond the end portion 50'b of the catheter, this providing an opening of the port equal to about one-third of that of port 59 itself. We conveniently refer to this portion of the opening as 59a. While the major portion of the blood exits through port 55', and thence to the arterial tree, a minor portion exits through port 5% to supply the coronary arteries. The amount of this minor portion, however, and the conditions of pressure associated therewith are not sufficient to discharge blood back into the incompetent left ventricle.
It will be seen that in the method and apparatus of our invention the content of the left ventricle of the heart is exhausted with a suction stroke. Yet, even with an incompetent aortic valve, any backflow of blood under the pressure condi tions obtaining with a succeeding discharge stroke, there is no undue reverse filling as encountered with normal operation of a defective heart with incompetent valve.
Thus, it will be seen that we provide in our invention a method and apparatus in which the various objects hereinbefore set forth are successfully had. The method and apparatus is simple, direct and reliable.
Since many embodiments may be made of our invention, and since many changes may be made in the embodiments hereinbefore set forth, it should be understood that all matter described herein, or shown in the accompanying drawings, is to be interpreted as illustrative, and not by way oflimitation.
1. Method for augmenting the action of an ailing heart having associated aorta and arterial tree supplied thereby and coronary arteries supplying the heart itself wherein an open ended catheter is inserted into the aortic, or left subclavian artery, to a point adjacent the aortic valve, comprising in sequential operation sucking blood from said aorta through said catheter during systolic heart pulsation, while blocking backflow from the said arterial tree; and on reverse cycle forcing the major portion of the said blood back through said catheter into the arterial tree while forcing a minor portion into the said coronary arteries during diastolic period.
2. Method according to claim I wherein about two-thirds of the blood on reverse cycle is supplied the arterial tree and about one-third is supplied the coronary arteries of the heart itself.
3 Heart assist device comprising catheter means including an elongated member with a bore extending therethrough and having a distal end with opening therein and a second opening back from said first-mentioned opening; expandible and imperforate membrane valve means flaring out circumferentially and extending radially extending about said catheter means from a point between said two openings; valve means engaging said catheter closing said second opening upon a suction being established in said catheter; and valve means within said catheter largely closing said first-mentioned opening upon a pressure being established in said catheter.
4. Device according to claim 3 wherein said catheter engaging valve means is in the form of an expandible sleeve positioned externally of said catheter and secured thereto; and said valve means within the catheter is in the form of an expandible sleeve positioned internally of said catheter and secured thereto. I I
5. Device according to claim 3 wherein said catheter engag-
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3071137 *||Aug 18, 1960||Jan 1, 1963||Niebel Benjamin W||Animated intestinal tube|
|US3266487 *||Jun 4, 1963||Aug 16, 1966||Sundstrand Corp||Heart pump augmentation system and apparatus|
|US3426743 *||Oct 27, 1964||Feb 11, 1969||United Aircraft Corp||Heart pump augmentation system|
|US3472230 *||Dec 19, 1966||Oct 14, 1969||Fogarty T J||Umbrella catheter|
|US3504662 *||May 16, 1967||Apr 7, 1970||Avco Corp||Intra-arterial blood pump|
|US3516410 *||Jan 3, 1968||Jun 23, 1970||Hakim Salomon||Cerebro-ventricular catheter|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3769983 *||Aug 26, 1970||Nov 6, 1973||A Meray||Medical devices|
|US3995617 *||May 31, 1972||Dec 7, 1976||Watkins David H||Heart assist method and catheter|
|US4014317 *||Feb 18, 1972||Mar 29, 1977||The United States Of America As Represented By The Department Of Health, Education And Welfare||Multipurpose cardiocirculatory assist cannula and methods of use thereof|
|US4407271 *||May 25, 1981||Oct 4, 1983||Peter Schiff||Apparatus for left heart assist|
|US4531936 *||Jan 12, 1983||Jul 30, 1985||Gordon Robert T||Device and method for the selective delivery of drugs to the myocardium|
|US4535757 *||Mar 12, 1982||Aug 20, 1985||Webster Wilton W Jr||Autoinflatable catheter|
|US4592340 *||May 2, 1984||Jun 3, 1986||Boyles Paul W||Artificial catheter means|
|US4655748 *||Sep 4, 1985||Apr 7, 1987||Aisin Seiki Kabushikikaisha||Cannula for infusion of fluid|
|US4705507 *||Apr 28, 1986||Nov 10, 1987||Boyles Paul W||Arterial catheter means|
|US4785795 *||Jan 14, 1987||Nov 22, 1988||Abiomed Cardiovascular, Inc.||High-frequency intra-arterial cardiac support system|
|US4857054 *||Jul 15, 1988||Aug 15, 1989||Eastman Kodak Company||Perfusion angioplasty catheter with pump assist|
|US4902272 *||Jun 17, 1987||Feb 20, 1990||Abiomed Cardiovascular, Inc.||Intra-arterial cardiac support system|
|US5024668 *||Jan 20, 1987||Jun 18, 1991||Rocky Mountain Research, Inc.||Retrograde perfusion system, components and method|
|US5092844 *||Apr 10, 1990||Mar 3, 1992||Mayo Foundation For Medical Education And Research||Intracatheter perfusion pump apparatus and method|
|US5100385 *||Sep 28, 1990||Mar 31, 1992||C. R. Bard, Inc.||Fast purge balloon dilatation catheter|
|US5147388 *||Mar 5, 1991||Sep 15, 1992||Kenji Yamazaki||Auxiliary artificial heart of the embedded-in-body type|
|US5163921 *||Oct 4, 1990||Nov 17, 1992||Feiring Andrew J||Valved perfusion cardiovascular catheters|
|US5224933 *||Mar 23, 1992||Jul 6, 1993||C. R. Bard, Inc.||Catheter purge device|
|US5290263 *||Jul 27, 1992||Mar 1, 1994||Regents Of The University Of Minnesota||Bidirectional check valve catheter|
|US5827237 *||Jun 17, 1996||Oct 27, 1998||Cardeon Corporation||Dual lumen catheter with controlled antegrade and retrograde fluid flow|
|US5833671 *||Jun 17, 1996||Nov 10, 1998||Cardeon Corporation||Triple lumen catheter with controllable antegrade and retrograde fluid flow|
|US5916193 *||Nov 30, 1996||Jun 29, 1999||Heartport, Inc.||Endovascular cardiac venting catheter and method|
|US6007479 *||Jul 8, 1996||Dec 28, 1999||H.D.S. Systems Ltd.||Heart assist system and method|
|US6059757 *||Jun 18, 1996||May 9, 2000||Cardeon||Single lumen catheter with controlled antegrade and retrograde flow|
|US6083215 *||Jul 17, 1995||Jul 4, 2000||Milavetz; James J.||Method and apparatus for antegrade coronary perfusion|
|US6110145 *||Apr 14, 1998||Aug 29, 2000||Cardeon Corporation||Catheter system for surgical access and circulatory support of the heart|
|US6200260||Oct 2, 1998||Mar 13, 2001||Fore Flow Corporation||Implantable heart assist system|
|US6245007 *||Jan 28, 1999||Jun 12, 2001||Terumo Cardiovascular Systems Corporation||Blood pump|
|US6299575||Apr 25, 2000||Oct 9, 2001||Orqis Medical Corporation||Implantable heart assist system|
|US6387037||Dec 23, 1999||May 14, 2002||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US6390969||Apr 21, 2000||May 21, 2002||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US6428464||Apr 9, 1999||Aug 6, 2002||Orqis Medical Corporation||Implantable heart assist system|
|US6458096||Apr 5, 1996||Oct 1, 2002||Medtronic, Inc.||Catheter with autoinflating, autoregulating balloon|
|US6464662 *||Jul 26, 2000||Oct 15, 2002||Image-Guided Neurologics, Inc.||Drug delivery and catheter systems, apparatus and processes|
|US6533770||Jan 21, 1998||Mar 18, 2003||Heartport, Inc.||Cannula and method of manufacture and use|
|US6572579||Sep 13, 2000||Jun 3, 2003||Image-Guided Neurologics, Inc.||Drug delivery and catheter systems, apparatus and processes|
|US6579259||Jun 25, 1999||Jun 17, 2003||Heartport, Inc.||Endovacular cardiac venting catheter and method|
|US6610004||Feb 15, 2002||Aug 26, 2003||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US6685621||Jun 11, 2002||Feb 3, 2004||Orois Medical Corporation||Implantable heart assist system and method of applying same|
|US6749583||Sep 5, 2002||Jun 15, 2004||Medtronic, Inc.||Catheter with autoinflating, autoregulating balloon|
|US6889082||Nov 6, 2002||May 3, 2005||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US6974409 *||Feb 7, 2002||Dec 13, 2005||Intra-Vasc.Nl B.V.||Catheter pump, catheter and method for supporting organ perfusion|
|US7125376||Apr 7, 2003||Oct 24, 2006||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7144365||Dec 5, 2003||Dec 5, 2006||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7267660 *||Nov 20, 2002||Sep 11, 2007||Cardiac Assist, Inc.||Method and apparatus for treating a patient|
|US7331921||Jun 28, 2004||Feb 19, 2008||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7445592||Jun 10, 2004||Nov 4, 2008||Orqis Medical Corporation||Cannulae having reduced flow resistance|
|US7458929||May 3, 2005||Dec 2, 2008||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7513863||Jun 28, 2004||Apr 7, 2009||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7588531||May 3, 2006||Sep 15, 2009||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7591778||May 3, 2006||Sep 22, 2009||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7614997||Nov 10, 2009||Orqis Medical Corporation||Implantable heart assist system and method of applying same|
|US7909794||Jun 1, 2004||Mar 22, 2011||Medtronic, Inc.||Catheter with autoinflating, autoregulating balloon|
|US7988655 *||Aug 2, 2011||Pulsecath B.V.||Catheter pump, catheter and fittings therefore and methods of using a catheter pump|
|US7993260||Aug 9, 2011||Thoratec Corporation||Implantable heart assist system and method of applying same|
|US8052749||Nov 8, 2011||Sadra Medical, Inc.||Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements|
|US8182528||Dec 23, 2003||May 22, 2012||Sadra Medical, Inc.||Locking heart valve anchor|
|US8231670||Jul 31, 2012||Sadra Medical, Inc.||Repositionable heart valve and method|
|US8246678||Mar 9, 2007||Aug 21, 2012||Sadra Medicl, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US8252052||Aug 28, 2012||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US8328868||Dec 11, 2012||Sadra Medical, Inc.||Medical devices and delivery systems for delivering medical devices|
|US8343213||Oct 21, 2004||Jan 1, 2013||Sadra Medical, Inc.||Leaflet engagement elements and methods for use thereof|
|US8579962||Dec 20, 2005||Nov 12, 2013||Sadra Medical, Inc.||Methods and apparatus for performing valvuloplasty|
|US8584678||Feb 4, 2011||Nov 19, 2013||Guillermo L. Pol||Medical tubes for selective mechanical ventilation of the lungs|
|US8603160||Dec 23, 2003||Dec 10, 2013||Sadra Medical, Inc.||Method of using a retrievable heart valve anchor with a sheath|
|US8617236||Nov 2, 2011||Dec 31, 2013||Sadra Medical, Inc.||Medical devices and delivery systems for delivering medical devices|
|US8623076||Sep 22, 2011||Jan 7, 2014||Sadra Medical, Inc.||Low profile heart valve and delivery system|
|US8623078||Jun 8, 2011||Jan 7, 2014||Sadra Medical, Inc.||Replacement valve and anchor|
|US8668733||Nov 12, 2008||Mar 11, 2014||Sadra Medical, Inc.||Everting heart valve|
|US8828078||Sep 20, 2005||Sep 9, 2014||Sadra Medical, Inc.||Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements|
|US8840662||Oct 27, 2011||Sep 23, 2014||Sadra Medical, Inc.||Repositionable heart valve and method|
|US8840663||Dec 23, 2003||Sep 23, 2014||Sadra Medical, Inc.||Repositionable heart valve method|
|US8858620||Jun 10, 2011||Oct 14, 2014||Sadra Medical Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US8894703||Jun 22, 2011||Nov 25, 2014||Sadra Medical, Inc.||Systems and methods for delivering a medical implant|
|US8900115||Jul 1, 2011||Dec 2, 2014||Thoratec Corporation||Implantable heart assist system and method of applying same|
|US8992608||Jun 26, 2009||Mar 31, 2015||Sadra Medical, Inc.||Everting heart valve|
|US8998976||Jul 12, 2012||Apr 7, 2015||Boston Scientific Scimed, Inc.||Coupling system for medical devices|
|US9005273||Apr 4, 2007||Apr 14, 2015||Sadra Medical, Inc.||Assessing the location and performance of replacement heart valves|
|US9011521||Dec 13, 2011||Apr 21, 2015||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US9277991||Dec 31, 2013||Mar 8, 2016||Boston Scientific Scimed, Inc.||Low profile heart valve and delivery system|
|US9308085||Sep 23, 2014||Apr 12, 2016||Boston Scientific Scimed, Inc.||Repositionable heart valve and method|
|US9320599||Sep 24, 2014||Apr 26, 2016||Boston Scientific Scimed, Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US9358106||Nov 11, 2013||Jun 7, 2016||Boston Scientific Scimed Inc.||Methods and apparatus for performing valvuloplasty|
|US9358110||Dec 31, 2013||Jun 7, 2016||Boston Scientific Scimed, Inc.||Medical devices and delivery systems for delivering medical devices|
|US20010003795 *||Jan 12, 2001||Jun 14, 2001||Mitta Suresh||Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart|
|US20030069468 *||Nov 6, 2002||Apr 10, 2003||Bolling Steven F.||Implantable heart assist system and method of applying same|
|US20030093062 *||Nov 20, 2002||May 15, 2003||James Fonger||Method and apparatus for treating a patient|
|US20040019251 *||Apr 7, 2003||Jan 29, 2004||Anthony Viole||Implantable heart assist system and method of applying same|
|US20040220522 *||Jun 1, 2004||Nov 4, 2004||Medtronic, Inc.||Catheter with autoinflating, autoregulating balloon|
|US20040236173 *||Jun 28, 2004||Nov 25, 2004||Anthony Viole||Implantable heart assist system and method of applying same|
|US20050085683 *||Oct 15, 2003||Apr 21, 2005||Bolling Steven F.||Implantable heart assist system and method of applying same|
|US20050131385 *||Dec 12, 2003||Jun 16, 2005||Bolling Steven F.||Cannulae for selectively enhancing blood flow|
|US20050256363 *||May 3, 2005||Nov 17, 2005||Bolling Steven F||Implantable heart assist system and method of applying same|
|US20060270892 *||May 3, 2006||Nov 30, 2006||Bolling Steven F||Implantable heart assist system and method of applying same|
|US20060276681 *||May 3, 2006||Dec 7, 2006||Bolling Steven F||Implantable heart assist system and method of applying same|
|US20070162107||Mar 9, 2007||Jul 12, 2007||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US20090149695 *||Jan 9, 2009||Jun 11, 2009||Pulsecath B.V.||Catheter pump, catheter and fittings therefore and methods of using a catheter pump|
|US20110186053 *||Aug 4, 2011||Pol Guillermo L||Medical Tubes for Selective Mechanical Ventilation of the Lungs|
|CN104174078A *||Sep 15, 2014||Dec 3, 2014||湖南埃普特医疗器械有限公司||Left ventricle auxiliary device|
|EP0018179A2 *||Apr 11, 1980||Oct 29, 1980||Regents Of The University Of Minnesota||Catheter tip for infusion|
|EP0238952A2 *||Mar 13, 1987||Sep 30, 1987||Pfrimmer-Viggo GmbH + Co. KG||Catheter for percutaneous gastrotomy|
|EP0364293A2 *||Oct 13, 1989||Apr 18, 1990||Kensey Nash Corporation||Blood pumping catheter|
|EP2263732A2 *||Nov 10, 2004||Dec 22, 2010||Thoratec Corporation||Cannulae having a redirecting tip|
|WO1983003204A1 *||Mar 12, 1982||Sep 29, 1983||Webster, Wilton, W., Jr.||Autoinflatable catheter|
|WO1997002850A1 *||Jul 8, 1996||Jan 30, 1997||Medicard Ltd.||Heart assist system|
|WO1997037714A1 *||Feb 5, 1997||Oct 16, 1997||Medtronic, Inc.||Catheter with autoinflating, autoregulating balloon|
|WO1997048436A2 *||Jun 17, 1997||Dec 24, 1997||Cardeon Corporation||Externally valved catheter for controlled antegrade and retrograde fluid flow|
|WO1997048436A3 *||Jun 17, 1997||May 7, 1998||Cardeon Corp||Externally valved catheter for controlled antegrade and retrograde fluid flow|
|WO1999030765A1 *||Dec 14, 1998||Jun 24, 1999||Cardeon Corporation||Perfusion shunt apparatus and method|
|WO2000013736A1 *||Sep 3, 1998||Mar 16, 2000||H.D.S. Systems, Ltd.||Finned-tip flow guided catheters|
|U.S. Classification||604/192, 604/6.16, 604/247, 604/28, 600/18|
|International Classification||A61M25/01, A61M25/04, A61M25/00|
|Cooperative Classification||A61M25/0075, A61M25/0125, A61M25/04|
|European Classification||A61M25/00T20A, A61M25/01C7, A61M25/04|