US3612059A - Heat exchanger for blood during transfusions - Google Patents

Heat exchanger for blood during transfusions Download PDF

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US3612059A
US3612059A US16762A US3612059DA US3612059A US 3612059 A US3612059 A US 3612059A US 16762 A US16762 A US 16762A US 3612059D A US3612059D A US 3612059DA US 3612059 A US3612059 A US 3612059A
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flow channels
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Robert A Ersek
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NEUROMEDICS Inc A CORP OF TX
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Assigned to INTERMEDICS, INC., INTERMEDICS CARDIASSIST, INC., INTERMEDICS INTRAOCULAR, INC., SURGITRONICS CORPORATION, CARBOMEDICS, INC., NEUROMEDICS, INC., CALCITEK, INC., TEXAS CORPORATION AND AMERICAN PACEMAKER CORPORATION, A CORP OF MASS. reassignment INTERMEDICS, INC., INTERMEDICS CARDIASSIST, INC., INTERMEDICS INTRAOCULAR, INC., SURGITRONICS CORPORATION, CARBOMEDICS, INC., NEUROMEDICS, INC., CALCITEK, INC., TEXAS CORPORATION AND AMERICAN PACEMAKER CORPORATION, A CORP OF MASS. SECURED PARTY HEREBY RELEASE THE SECURITY INTEREST IN AGREEMENT RECORDED AUGUST 5, 1985. REEL 4434 FRAMES 728-782 Assignors: CITIBANK, N.A.
Assigned to INTERMEDICS, INC., INTERMEDICS CARDIASSIST, INC., INTERMEDICS INTRAOCULAR, INC., SURGITRONICS CORPORATION, CARBOMEDICS, INC., NEUROMEDICS, INC., CALCITEK, INC., INTERVASCULAR, INC., AND MASTER IMAGES, INC., TEXAS CORPORATIONS, AND AMERICANPACEMAKER CORPORATION, A CORP. OF MA. reassignment INTERMEDICS, INC., INTERMEDICS CARDIASSIST, INC., INTERMEDICS INTRAOCULAR, INC., SURGITRONICS CORPORATION, CARBOMEDICS, INC., NEUROMEDICS, INC., CALCITEK, INC., INTERVASCULAR, INC., AND MASTER IMAGES, INC., TEXAS CORPORATIONS, AND AMERICANPACEMAKER CORPORATION, A CORP. OF MA. SAID PARTIES RECITES OBLIGATIONS RECITED IN SECURITY AGREEMENT RECORDED SEPTEMBER 17, 1984 REEL 4303 FRAMES 077-127 HAVE BEEN PAID IN FULL ALL SEE RECORD FOR DETIALS Assignors: CITIBANK, N.A., INDIVIDUALLY AND AS AGENT FOR BANK OF AMERICA NATIONAL TRUST AND SAVINGS ASSOCIATION, THE CHASE MANHATTAN BANK, N.A., THE FIRST NATIONAL BANK OF CHICAGO, TRUST COMPANY BANK, FIRST FREEPORT NATIONAL BANK OF BRAZOSPORT BANK OF TEXAS
Assigned to INTERMEDICS, INC., SURGITRONICS CORPORATION, INTERMEDICS CARDIASSIST, INC., CARBO-MEDICS, INC., INTERMEDICS INTRAOCULAR, INC. reassignment INTERMEDICS, INC. RELEASED BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: CHASE COMMERCIAL CORPORATION
Assigned to NEUROMEDICS, INC., A TEXAS CORP., INTERMEDICS INTRAOCULAR, INC., A TEXAS CORP., INTERMEDICS, INC., A TEXAS CORP., CARBOMEDICS, INC., A TEXAS CORP., AMERICAN PACEMAKER CORPORATION, A MASSACHUSETTS CORP., INTERMEDICS CARDIASSIST, INC., A TEXAS CORP., CALCITEK, INC., A TEXAS CORP., SURGITRONICS CORPORATION, A TEXAS CORP. reassignment NEUROMEDICS, INC., A TEXAS CORP. RELEASED BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: B. A. LEASING CORPORATION
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3613—General characteristics of the apparatus related to heating or cooling by body heat

Definitions

  • the present invention relates generally to a means for controlling the temperature of intravenous fluids being administered to a patient, and more particularly relates to such a structure which is adapted to be secured to the surface of either the patient or attending party for bringing the temperature of intravenous fluids to a level closely approximating that of the normal system.
  • the apparatus of the present invention is, on the other hand, simple, disposable, sterile, and is essentially foil-safe.
  • the structure provides low resistance to normal fluid flow, and the patients or attending partys body heat is utilized to regulate the temperature of the intravenous fluid being injected.
  • the apparatus of the present invention consists simply of two layers of thin plastic film which is inherently heat scalable, or which is coated with a film of adhesive which will bond the two layers together.
  • Generally parallel flow channels are created so that multiple parallel low-resistance high-flow channels are formed.
  • the structure is placed in series with the intravenous fluids, and is adapted to be secured to the patients skin or to the skin of an attending party.
  • the inner surface adjacent the body is preferably coated with a highly thermally emissive film in order to absorb heat from the body rapidly, while the outer surface is coated with aluminum or other thermally reflective film in order to prevent or retard radiant dissipation of heat into the environment Therefore, the heat exchange occurs utilizing the bodys own temperature regulating mechanisms to achieve the desired temperature of the infused fluid prior to the time that it enters the body of the patient.
  • FIG. 1 is a perspective view of a heat exchanger device prepared in accordance with the present invention
  • FIG. 2 is a detail sectional view of the flow channels of the device shown in FIG. I, this figure showing the thermally emissive and thermally reflective coatings applied to the surface of the structure, along with an adhesive bonding layer;
  • FIG. 3 is a view of the device of FIG. lsecured to the arm of a patient receiving intravenous fluids.
  • the intravenous heat exchanger shown in FIG. 1, and generally designated 10 includes a pair of op posed films 11 and 12, these films being bonded together firmly along and around substantially the entire periphery thereof.
  • the structure of FIG. I is preferably in the form of a rectangular parallelopiped, having an elongated axis generally parallel to the broken axial line 13.
  • the films 11 and I2 are provided with an inlet orifice as at 15, for accommodating fluid flow in the direction of the arrow 16, the inlet orifice communicating with an inlet manifold as at 17, the manifold introducing the inlet to a plurality of generally parallelly disposed flow channels as at l8, l9, and 20, for example.
  • seals are formed between the films 11 and 12, such as at 21, 22 and 23. These seals thereby form a plurality of generally parallelly disposed flow channels which extend between the inlet manifold 17, and an outlet manifold shown at 25.'The outlet manifold 25 communicates with an outlet orifice as at 26.
  • suitable fluid-type coupling arrangements are provided, such as, for example, by the use of extruded tubing or the like which may be bonded to the inlet and outlet orifices, such as at 27.
  • the individual flow channels such as are shown at 18, I9 and 20, are separated by bonded webs as at 22 and 23, as indicated hereinabove.
  • These webs 22 and 23 may be fonned by either thermal welding, or adhesive bonding techniques.
  • the lower surface of the structure such as the lower surface of the film 12, is provided with a highly thermally emissive coating such as carbon black or the like, this coating being applied directly to the surface of the film l2, and shown at 28.
  • a pressure sensitive adhesive is applied to the film I2 as at 29, this adhesive permitting direct attachment or bonding of a heat exchanger structure to the surface of the skin of either the patient or the skin of an attending party.
  • the outer surface of the upper film II is coated with a highly thermally reflective coating such as aluminum or other metallic reflective coating 30.
  • a highly thermally reflective coating such as aluminum or other metallic reflective coating 30.
  • strap members such as the straps 31, 32, 33, and 34 may be employed. These straps permit fast attachment of the structure to the skin surface, and also provide for a minimum risk to mechanical compression of the individual flow channels due to a tight bond being formed between the heat exchanger device and the skin surface.
  • the structure is provided with a plurality of generally parallelly disposed flow channels which provide for a high-low rate, maximum exposure to the desirable thermal environment, all of this being accomplished with a minimum of impedance to flow.
  • silicone rubber for treatment with blood, it is normally desired that silicone rubber be utilized in order to prevent anomalous effects from occurring in the blood solution upon contact with the film surface. This is, of course, desirable inasmuch as surface contact is at a maximum in this type of structure.
  • the device is readily introduced into flow systems, and is readily attached or secured to the skin surface of either the patient or anattending party.
  • the device is quick, simple, and reliable. Any failure or rupture of the structure will, of course, result in a fail-safe condition inasmuch as the fluids will be readily visible, thus permitting corrective measures. to be taken prior to the time that the patient may be harmed.
  • the device has a size measuring, approximately, 3 inches on a side, with the flow channel preferably being less than about 3 inches in length.
  • Apparatus for controlling the temperature of intravenous fluids being infused to a patient utilizing a persons body heat comprising:
  • first means defining an inlet orifice along one edge thereof communicating with an inlet manifold at one end of said parallel flow channels and second means defining heat can be transmitted into the flow channels and held therein so as to effect heating of the fluid being infused into the patient.
  • the means as defined in claim 1 being particularly characterized in that means are provided along said flexible films for attaching the structure to the skin surface of a human.
  • the means as defined in claim 1 being particularly characterized in that pressure sensitive coatings are applied along the surface coated with thermally emissive material for securing said structure to the surface of the skin of a human.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Means for controlling the temperature of intravenous fluids being administered to a patient and comprising a pair of relatively thin films of flexible silicone rubber bonded together to form a generally rectangular parallelepiped having a pair of opposed major surfaces and having a plurality of generally parallelly disposed flow channels extending therebetween, the flow channels being arranged transversely to the elongated axis of said parallelepiped; means defining an inlet orifice along one edge thereof communicating with an inlet manifold at one end of said parallel flow channels and an outlet orifice along the opposite edge thereof communicating with an outlet manifold at the opposite end of said flow channels; and a highly thermally emissive coating applied along one of said major surfaces, and a highly thermally reflective coating applied to the opposed major surface.

Description

United States Patent Robert A Ersek [72] Inventor 8806 Minnetonka Blvd., Minneapolis, Minn. 55436 [21] App]. No. 16,762" [22] Filed Mar. 5, 1970 [45] Patented Oct. 12, 1971 [54] HEAT EXCHANGER FOR BLOOD DURING TRANSFUSIONS 6 Claims, 3 Drawing Figs.
[52] U.S. Cl 128/399, 128/214, 165/46,165/133 [51] Int. Cl A611 07/00 [50] Field of Search 128/214, 214.2, 254, 258, 399, 402, 403; 165/46, 133
[ 56] References Cited UNITED STATES PATENTS 2,397,232 3/1946 Barnes et al. 128/399 X Primary Examiner-Dalton L. Truluck Attorney-Orrin M. I-Iaugen ABSTRACT: Means for controlling the temperature of intravenous fluids being administered to a patient and comprising a pair of relatively thin films of flexible silicone rubber bonded together to form a generally rectangular parallelepiped having a pair of opposed major surfaces and having a plurality of generally parallelly disposed flow channels extending therebetween, the flow channels being arranged transversely to the elongated axis of said parallelepiped; means defining an inlet orifice along one edge thereof communicating with an inlet manifold at one end of said parallel flow channels and an outlet orifice along the opposite edge thereof communicating with an outlet manifold at the opposite end of said flow channels; and a highly thermally emissive coating applied along one of said major surfaces, and a highly thermally reflective coating applied to the opposed major surface.
30 Metollized Ref Ieclive Cooling 28 (Block coating) 29 (Surface adhesive coating PATENTED mm 1 2 I97! $3,612,059
3O Metallized Ref leciive Coating 28 (Black coating) "W N 2O 29 (Surface adhesive coating) INVENTOR.
ROBERT A. Ersek HEAT EXCHANGER FOR BLOOD DURING TRANSFUSIONS The present invention relates generally to a means for controlling the temperature of intravenous fluids being administered to a patient, and more particularly relates to such a structure which is adapted to be secured to the surface of either the patient or attending party for bringing the temperature of intravenous fluids to a level closely approximating that of the normal system.
At the present time, elaborate electrical, mechanical, and other devices are utilized for controlling the temperature of fluids being administered to a patient. Frequently, large volumes of fluids such as blood or the like are required for initially priming or preparing the devices, and such volumes being of course, lost. In addition, the presently employed electrical or mechanical units are expensive, and dangerous when a breakdown occurs during use. The apparatus of the present invention is, on the other hand, simple, disposable, sterile, and is essentially foil-safe. The structure provides low resistance to normal fluid flow, and the patients or attending partys body heat is utilized to regulate the temperature of the intravenous fluid being injected.
Recent studies have shown that the rhythm of the heart may be intrinsically disturbed if solutions at a significantly lower temperature are administered to the heart muscle itself. This disturbing activity may occur when cold blood or other intravenous solutions are rapidly infused.
Briefly, the apparatus of the present invention consists simply of two layers of thin plastic film which is inherently heat scalable, or which is coated with a film of adhesive which will bond the two layers together. Generally parallel flow channels are created so that multiple parallel low-resistance high-flow channels are formed. The structure is placed in series with the intravenous fluids, and is adapted to be secured to the patients skin or to the skin of an attending party. The inner surface adjacent the body is preferably coated with a highly thermally emissive film in order to absorb heat from the body rapidly, while the outer surface is coated with aluminum or other thermally reflective film in order to prevent or retard radiant dissipation of heat into the environment Therefore, the heat exchange occurs utilizing the bodys own temperature regulating mechanisms to achieve the desired temperature of the infused fluid prior to the time that it enters the body of the patient. I
Therefore, it is an object of the present invention to provide an improved device which functions as a heat exchanger for intravenous solutions, the structure utilizing the body temperature of the patient or attending party for achieving a temperature balance in the solutions being infused.
It is yet a further object of the present invention to provide an improved heat exchanger device which is fabricated from a pair of thin flexible films bonded together so as to form a plurality of parallelly disposed flow channels, these channels providing a plurality of low-resistance high-flow rate paths.
It is yet a further object of the present invention to'provide an improved heat exchanger device for modifying the temperature of intravenous solutions being infused, the structure being adapted to be mounted adjacent the patients skin or the skin of an attending party, the surface of the heat exchanger device adjacent the skin being coated with a highly thermally emissive film, the surface remote from the patients skin being coated with a highly thermally reflective coating.
Other and further objects of the present invention will become apparent to those skilled in the art upon a study of the following specification, appended claims, and accompanying drawing wherein:
FIG. 1 is a perspective view of a heat exchanger device prepared in accordance with the present invention;
FIG. 2 is a detail sectional view of the flow channels of the device shown in FIG. I, this figure showing the thermally emissive and thermally reflective coatings applied to the surface of the structure, along with an adhesive bonding layer; and
FIG. 3 is a view of the device of FIG. lsecured to the arm of a patient receiving intravenous fluids.
In accordance with the preferred modification of the present invention, the intravenous heat exchanger shown in FIG. 1, and generally designated 10, includes a pair of op posed films 11 and 12, these films being bonded together firmly along and around substantially the entire periphery thereof. The structure of FIG. I is preferably in the form of a rectangular parallelopiped, having an elongated axis generally parallel to the broken axial line 13. The films 11 and I2 are provided with an inlet orifice as at 15, for accommodating fluid flow in the direction of the arrow 16, the inlet orifice communicating with an inlet manifold as at 17, the manifold introducing the inlet to a plurality of generally parallelly disposed flow channels as at l8, l9, and 20, for example. Intermediate the individual flow channels l8, l9, and 20, seals are formed between the films 11 and 12, such as at 21, 22 and 23. These seals thereby form a plurality of generally parallelly disposed flow channels which extend between the inlet manifold 17, and an outlet manifold shown at 25.'The outlet manifold 25 communicates with an outlet orifice as at 26. In order to accommodate mounting of the structure on an in-line basis, suitable fluid-type coupling arrangements are provided, such as, for example, by the use of extruded tubing or the like which may be bonded to the inlet and outlet orifices, such as at 27.
With attention now being directed to FIG. 2 of the drawing, the individual flow channels such as are shown at 18, I9 and 20, are separated by bonded webs as at 22 and 23, as indicated hereinabove. These webs 22 and 23 may be fonned by either thermal welding, or adhesive bonding techniques. The lower surface of the structure, such as the lower surface of the film 12, is provided with a highly thermally emissive coating such as carbon black or the like, this coating being applied directly to the surface of the film l2, and shown at 28. In addition, a pressure sensitive adhesive is applied to the film I2 as at 29, this adhesive permitting direct attachment or bonding of a heat exchanger structure to the surface of the skin of either the patient or the skin of an attending party.
In order to enhance the thermal environment, the outer surface of the upper film II is coated with a highly thermally reflective coating such as aluminum or other metallic reflective coating 30. These materials are, of course, commercially available and may be utilized to an advantage in this type of structure.
As an alternative to the use of a pressure sensitive adhesive film along the base of the structure, strap members such as the straps 31, 32, 33, and 34 may be employed. These straps permit fast attachment of the structure to the skin surface, and also provide for a minimum risk to mechanical compression of the individual flow channels due to a tight bond being formed between the heat exchanger device and the skin surface.
It will be appreciated that the structure is provided with a plurality of generally parallelly disposed flow channels which provide for a high-low rate, maximum exposure to the desirable thermal environment, all of this being accomplished with a minimum of impedance to flow.
It will be appreciated that a variety of materials may be employed, such as, for example, silicone rubber, polyethylene, polypropylene, or the. like. For treatment with blood, it is normally desired that silicone rubber be utilized in order to prevent anomalous effects from occurring in the blood solution upon contact with the film surface. This is, of course, desirable inasmuch as surface contact is at a maximum in this type of structure.
The device is readily introduced into flow systems, and is readily attached or secured to the skin surface of either the patient or anattending party. Thus, the device is quick, simple, and reliable. Any failure or rupture of the structure will, of course, result in a fail-safe condition inasmuch as the fluids will be readily visible, thus permitting corrective measures. to be taken prior to the time that the patient may be harmed.
For most applications, the device has a size measuring, approximately, 3 inches on a side, with the flow channel preferably being less than about 3 inches in length.
It will be appreciated, of course, that the examples provided herein are for purposes of illustration only and are not disclosed by way of limitation.
What is claimed is:
,1. Apparatus for controlling the temperature of intravenous fluids being infused to a patient utilizing a persons body heat comprising:
a. a pair of relatively thin flexible films bonded together to form a generally rectangular parallelepiped having a pair of opposed major surfaces and having a plurality of generally parallelly disposed flow channels extending therebetween:
b. first means defining an inlet orifice along one edge thereof communicating with an inlet manifold at one end of said parallel flow channels and second means defining heat can be transmitted into the flow channels and held therein so as to effect heating of the fluid being infused into the patient.
2. The means as defined in claim 1 being particularly 5 characterized in that said thermally emissive and thermally reflective coatings are applied externally of said generally rectangular parallelepiped.
3. The means as defined in claim 1 being particularly characterized in that said relatively thin flexible films are fabricated from silicone rubber.
4. The means as defined in claim 1 being particularly characterized in that means are provided along said flexible films for attaching the structure to the skin surface of a human.
5. The means as defined in claim 1 being particularly characterized in that pressure sensitive coatings are applied along the surface coated with thermally emissive material for securing said structure to the surface of the skin of a human.
6. The means as defined in claim 1 being particularly

Claims (5)

  1. 2. The means as defined in claim 1 being particularly characterized in that said thermally emissive and thermally reflective coatings are applied externally of said generally rectangular parallelopiped.
  2. 3. The means as defined in claim 1 being particularly characterized in that said relatively thin flexible films are fabricated from silicone rubber.
  3. 4. The means as defined in claim 1 being particularly characterized in that means are provided along said flexible films for attaching the structure to the skin surface of a human.
  4. 5. The means as defined in claim 1 being particularly characterized in that pressure sensitive coatings are applied along the surface coated with thermally emissive material for securing said structure to the surface of the skin of a human.
  5. 6. The means as defined in claim 1 being particularly characterized in that said rectangular parallelopiped has an elongated axis and a shorter transverse axis, and said parallelly disposed flow channels are generally parallel to said transverse axis.
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Cited By (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048980A (en) * 1976-03-08 1977-09-20 The United States Of America As Represented By The United States Energy Research And Development Administration Solar radiation absorbing material
US4092750A (en) * 1976-05-14 1978-06-06 Ellis Donald G Inflatable insulating apparatus
US4139004A (en) * 1977-02-17 1979-02-13 Gonzalez Jr Harry Bandage apparatus for treating burns
US4230175A (en) * 1977-02-15 1980-10-28 Hoechst Aktiengesellschaft Heat exchanger element
US4309592A (en) * 1977-10-07 1982-01-05 Guy Le Boeuf Electric heating device for heating sterilized fluids, such as blood
US4508123A (en) * 1983-06-01 1985-04-02 American Hospital Supply Corporation Thermodilution injectate assembly
US4735609A (en) * 1986-07-24 1988-04-05 Medical Industrial Technologies, Inc. IV fluid warmer
US4738119A (en) * 1987-02-09 1988-04-19 Westinghouse Electric Corp. Integral cooling garment for protection against heat stress
US4782212A (en) * 1986-11-17 1988-11-01 Bakke Allan P Electric blood warmer utilizing a metallic ribbon-flow cartridge
US4847470A (en) * 1987-12-14 1989-07-11 Bakke Allan P Electric blood warmer utilizing metallic ribbon flow cartridge and low thermal mass heating units
US4919134A (en) * 1987-07-31 1990-04-24 Becton, Dickinson And Company Thermoelectric chiller and automatic syringe
US4925743A (en) * 1987-03-31 1990-05-15 Nihon Food Culture Co., Ltd. Disposable body warmer and heat generating material therefor
US5125069A (en) * 1989-12-22 1992-06-23 Netherlands Health Sciences Blood warmer
US5245693A (en) * 1991-03-15 1993-09-14 In-Touch Products Co. Parenteral fluid warmer apparatus and disposable cassette utilizing thin, flexible heat-exchange membrane
US5254094A (en) * 1989-07-17 1993-10-19 Starkey David L Physiological fluid warmer
US5372608A (en) * 1993-08-12 1994-12-13 Johnson; Bertrand L. Circulating chilled-fluid therapeutic device
US5381510A (en) * 1991-03-15 1995-01-10 In-Touch Products Co. In-line fluid heating apparatus with gradation of heat energy from inlet to outlet
US5403281A (en) * 1992-09-25 1995-04-04 Minnesota Mining And Manufacturing Company Inline heat exchanger and cardioplegia system
US5601894A (en) * 1995-07-06 1997-02-11 Johns Hopkins Hospital Insulated intravenous administration tubing and drip chambers
US5634269A (en) * 1994-09-09 1997-06-03 Gas Research Institute Thin plastic-film heat exchanger for absorption chillers
US5846224A (en) * 1996-10-01 1998-12-08 Baxter International Inc. Container for use with blood warming apparatus
US6047108A (en) * 1996-10-01 2000-04-04 Baxter International Inc. Blood warming apparatus
US6467953B1 (en) 1999-03-30 2002-10-22 Medical Solutions, Inc. Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items
US6824528B1 (en) 1997-03-03 2004-11-30 Medical Solutions, Inc. Method and apparatus for pressure infusion and temperature control of infused liquids
US20050126750A1 (en) * 2003-11-18 2005-06-16 Mitsuo Yokozawa Flow-path constituting body
US7041941B2 (en) 1997-04-07 2006-05-09 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7090658B2 (en) 1997-03-03 2006-08-15 Medical Solutions, Inc. Temperature sensing device for selectively measuring temperature at desired locations along an intravenous fluid line
US7211104B2 (en) 2002-10-08 2007-05-01 Vital Wear, Inc. Contrast therapy system and method
US7276675B2 (en) 1997-04-07 2007-10-02 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7276046B1 (en) 2002-11-18 2007-10-02 Biosynergy, Inc. Liquid conductive cooling/heating device and method of use
US20080039815A1 (en) * 2004-02-17 2008-02-14 Genshirou Ogawa Infusion Fluid Warming Method, Infusion Fluid Warming Apparatus, and Infusion Fluid Warming Bag
US7611504B1 (en) 2004-03-09 2009-11-03 Patented Medical Solutions Llc Method and apparatus for facilitating injection of medication into an intravenous fluid line while maintaining sterility of infused fluids
US20100030306A1 (en) * 2002-10-08 2010-02-04 Howard Edelman Therapeutic Cranial Wrap for a Contrast Therapy System
US7658205B1 (en) 2002-12-19 2010-02-09 Vitalwear, Inc. Systems for a fluid circuit coupler
US7694693B1 (en) 2002-10-08 2010-04-13 Vitalwear, Inc. Mixing valve for a contrast therapy system
US7740611B2 (en) 2005-10-27 2010-06-22 Patented Medical Solutions, Llc Method and apparatus to indicate prior use of a medical item
US8052628B1 (en) 2002-10-08 2011-11-08 Vitalwear, Inc. Spinal column brace for a contrast therapy system
US8226605B2 (en) 2001-12-17 2012-07-24 Medical Solutions, Inc. Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion
US8226293B2 (en) 2007-02-22 2012-07-24 Medical Solutions, Inc. Method and apparatus for measurement and control of temperature for infused liquids
US8425579B1 (en) 2002-10-08 2013-04-23 Vitalwear, Inc. Therapeutic knee brace for a contrast therapy system
US9119912B2 (en) 2001-03-12 2015-09-01 Medical Solutions, Inc. Method and apparatus for controlling pressurized infusion and temperature of infused liquids
US9211381B2 (en) 2012-01-20 2015-12-15 Medical Solutions, Inc. Method and apparatus for controlling temperature of medical liquids
US9656029B2 (en) 2013-02-15 2017-05-23 Medical Solutions, Inc. Plural medical item warming system and method for warming a plurality of medical items to desired temperatures
WO2020143940A1 (en) * 2019-01-10 2020-07-16 B. Braun Melsungen Ag Throttle for heating infusate by means of body heat

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2397232A (en) * 1944-05-06 1946-03-26 Eugene L Barnes Flexible applicator
US2631410A (en) * 1945-08-20 1953-03-17 Libbey Owens Ford Glass Co Apparatus for forming flat glass
US3140716A (en) * 1961-06-26 1964-07-14 Baxter Laboratories Inc Heat exchanger for blood
US3315681A (en) * 1964-08-17 1967-04-25 Heinz F Poppendiek Means and techniques useful for changing temperature of fluids, particularly blood
US3388803A (en) * 1965-04-16 1968-06-18 Applied Biolog Sciences Lab In Wearable dialysis apparatus
US3485245A (en) * 1967-06-21 1969-12-23 Ibm Portable fluid heater

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2397232A (en) * 1944-05-06 1946-03-26 Eugene L Barnes Flexible applicator
US2631410A (en) * 1945-08-20 1953-03-17 Libbey Owens Ford Glass Co Apparatus for forming flat glass
US3140716A (en) * 1961-06-26 1964-07-14 Baxter Laboratories Inc Heat exchanger for blood
US3315681A (en) * 1964-08-17 1967-04-25 Heinz F Poppendiek Means and techniques useful for changing temperature of fluids, particularly blood
US3388803A (en) * 1965-04-16 1968-06-18 Applied Biolog Sciences Lab In Wearable dialysis apparatus
US3485245A (en) * 1967-06-21 1969-12-23 Ibm Portable fluid heater

Cited By (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048980A (en) * 1976-03-08 1977-09-20 The United States Of America As Represented By The United States Energy Research And Development Administration Solar radiation absorbing material
US4092750A (en) * 1976-05-14 1978-06-06 Ellis Donald G Inflatable insulating apparatus
US4230175A (en) * 1977-02-15 1980-10-28 Hoechst Aktiengesellschaft Heat exchanger element
US4139004A (en) * 1977-02-17 1979-02-13 Gonzalez Jr Harry Bandage apparatus for treating burns
US4309592A (en) * 1977-10-07 1982-01-05 Guy Le Boeuf Electric heating device for heating sterilized fluids, such as blood
US4508123A (en) * 1983-06-01 1985-04-02 American Hospital Supply Corporation Thermodilution injectate assembly
US4735609A (en) * 1986-07-24 1988-04-05 Medical Industrial Technologies, Inc. IV fluid warmer
US4782212A (en) * 1986-11-17 1988-11-01 Bakke Allan P Electric blood warmer utilizing a metallic ribbon-flow cartridge
US4738119A (en) * 1987-02-09 1988-04-19 Westinghouse Electric Corp. Integral cooling garment for protection against heat stress
US4925743A (en) * 1987-03-31 1990-05-15 Nihon Food Culture Co., Ltd. Disposable body warmer and heat generating material therefor
US4919134A (en) * 1987-07-31 1990-04-24 Becton, Dickinson And Company Thermoelectric chiller and automatic syringe
US4847470A (en) * 1987-12-14 1989-07-11 Bakke Allan P Electric blood warmer utilizing metallic ribbon flow cartridge and low thermal mass heating units
US5254094A (en) * 1989-07-17 1993-10-19 Starkey David L Physiological fluid warmer
US5125069A (en) * 1989-12-22 1992-06-23 Netherlands Health Sciences Blood warmer
US5245693A (en) * 1991-03-15 1993-09-14 In-Touch Products Co. Parenteral fluid warmer apparatus and disposable cassette utilizing thin, flexible heat-exchange membrane
US5381510A (en) * 1991-03-15 1995-01-10 In-Touch Products Co. In-line fluid heating apparatus with gradation of heat energy from inlet to outlet
US5403281A (en) * 1992-09-25 1995-04-04 Minnesota Mining And Manufacturing Company Inline heat exchanger and cardioplegia system
US5372608A (en) * 1993-08-12 1994-12-13 Johnson; Bertrand L. Circulating chilled-fluid therapeutic device
US5992508A (en) * 1994-09-09 1999-11-30 Gas Research Institute Thin plastic-film heat exchanger for absorption chillers
US5634269A (en) * 1994-09-09 1997-06-03 Gas Research Institute Thin plastic-film heat exchanger for absorption chillers
US5601894A (en) * 1995-07-06 1997-02-11 Johns Hopkins Hospital Insulated intravenous administration tubing and drip chambers
US5846224A (en) * 1996-10-01 1998-12-08 Baxter International Inc. Container for use with blood warming apparatus
US6047108A (en) * 1996-10-01 2000-04-04 Baxter International Inc. Blood warming apparatus
US8920387B2 (en) 1997-03-03 2014-12-30 Medical Solutions, Inc. Method and apparatus for pressure infusion and temperature control of infused liquids
US8313462B2 (en) 1997-03-03 2012-11-20 Medical Solutions, Inc. Method and apparatus for pressure infusion and temperature control of infused liquids
US7942851B2 (en) 1997-03-03 2011-05-17 Medical Solutions, Inc. Method and apparatus for pressure infusion and temperature control of infused liquids
US6824528B1 (en) 1997-03-03 2004-11-30 Medical Solutions, Inc. Method and apparatus for pressure infusion and temperature control of infused liquids
US7540864B2 (en) 1997-03-03 2009-06-02 Medical Solutions, Inc. Temperature sensing device for selectively measuring temperature at desired locations along an intravenous fluid line
US7090658B2 (en) 1997-03-03 2006-08-15 Medical Solutions, Inc. Temperature sensing device for selectively measuring temperature at desired locations along an intravenous fluid line
US7307245B2 (en) 1997-04-07 2007-12-11 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7276675B2 (en) 1997-04-07 2007-10-02 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7041941B2 (en) 1997-04-07 2006-05-09 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7417205B2 (en) 1997-04-07 2008-08-26 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US6722782B2 (en) 1999-03-30 2004-04-20 Medical Solutions, Inc. Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items
US6467953B1 (en) 1999-03-30 2002-10-22 Medical Solutions, Inc. Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items
US8821011B2 (en) 1999-03-30 2014-09-02 Medical Solutions, Inc. Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items
US6566631B2 (en) 1999-03-30 2003-05-20 Medical Solutions, Inc. Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items
US9119912B2 (en) 2001-03-12 2015-09-01 Medical Solutions, Inc. Method and apparatus for controlling pressurized infusion and temperature of infused liquids
US8226605B2 (en) 2001-12-17 2012-07-24 Medical Solutions, Inc. Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion
US9492624B2 (en) 2001-12-17 2016-11-15 Medical Solutions, Inc. Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion
US8920372B2 (en) 2001-12-17 2014-12-30 Medical Solutions, Inc. Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion
US8226698B2 (en) 2002-10-08 2012-07-24 Vitalwear, Inc. Therapeutic cranial wrap for a contrast therapy system
US20100030306A1 (en) * 2002-10-08 2010-02-04 Howard Edelman Therapeutic Cranial Wrap for a Contrast Therapy System
US8052628B1 (en) 2002-10-08 2011-11-08 Vitalwear, Inc. Spinal column brace for a contrast therapy system
US7211104B2 (en) 2002-10-08 2007-05-01 Vital Wear, Inc. Contrast therapy system and method
US8425579B1 (en) 2002-10-08 2013-04-23 Vitalwear, Inc. Therapeutic knee brace for a contrast therapy system
US7694693B1 (en) 2002-10-08 2010-04-13 Vitalwear, Inc. Mixing valve for a contrast therapy system
US7276046B1 (en) 2002-11-18 2007-10-02 Biosynergy, Inc. Liquid conductive cooling/heating device and method of use
US7658205B1 (en) 2002-12-19 2010-02-09 Vitalwear, Inc. Systems for a fluid circuit coupler
US20050126750A1 (en) * 2003-11-18 2005-06-16 Mitsuo Yokozawa Flow-path constituting body
US7715700B2 (en) * 2004-02-17 2010-05-11 Genshirou Ogawa Method, device, and bag for warming infusion liquid
US20080039815A1 (en) * 2004-02-17 2008-02-14 Genshirou Ogawa Infusion Fluid Warming Method, Infusion Fluid Warming Apparatus, and Infusion Fluid Warming Bag
US7611504B1 (en) 2004-03-09 2009-11-03 Patented Medical Solutions Llc Method and apparatus for facilitating injection of medication into an intravenous fluid line while maintaining sterility of infused fluids
US8845586B2 (en) 2004-03-09 2014-09-30 Patented Medical Solutions Llc Method and apparatus for facilitating injection of medication into an intravenous fluid line while maintaining sterility of infused fluids
US8636691B2 (en) 2005-10-27 2014-01-28 Patented Medical Solutions, Llc Method and apparatus to indicate prior use of a medical item
US8444599B2 (en) 2005-10-27 2013-05-21 Patented Medical Solutions, Llc Method and apparatus to indicate prior use of a medical item
US7740611B2 (en) 2005-10-27 2010-06-22 Patented Medical Solutions, Llc Method and apparatus to indicate prior use of a medical item
US8226293B2 (en) 2007-02-22 2012-07-24 Medical Solutions, Inc. Method and apparatus for measurement and control of temperature for infused liquids
US9211381B2 (en) 2012-01-20 2015-12-15 Medical Solutions, Inc. Method and apparatus for controlling temperature of medical liquids
US9764100B2 (en) 2012-01-20 2017-09-19 Medical Solutions, Inc. Method and apparatus for controlling temperature of medical liquids
US9656029B2 (en) 2013-02-15 2017-05-23 Medical Solutions, Inc. Plural medical item warming system and method for warming a plurality of medical items to desired temperatures
WO2020143940A1 (en) * 2019-01-10 2020-07-16 B. Braun Melsungen Ag Throttle for heating infusate by means of body heat
CN113507948A (en) * 2019-01-10 2021-10-15 贝朗梅尔松根股份公司 Throttle for heating by body-heating infusion device
US20220072223A1 (en) * 2019-01-10 2022-03-10 B. Braun Melsungen Ag Medical fluid-line arrangement and medical elastomeric pump having such a fluid-line arrangement

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