Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.


  1. Advanced Patent Search
Publication numberUS3654085 A
Publication typeGrant
Publication dateApr 4, 1972
Filing dateNov 17, 1969
Priority dateNov 26, 1968
Also published asDE1958314A1
Publication numberUS 3654085 A, US 3654085A, US-A-3654085, US3654085 A, US3654085A
InventorsFritz Bertil Willy Holm, Artur Valter Leopold Norr
Original AssigneeAga Ab
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Storage device for organ transplants
US 3654085 A
Abstract  available in
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)

April 4, 1972 A. v. L. NORR ErAL STORAGE DEVICE FOR ORGAN TRANSPLANTS Filed Nov. 17, 1969 INVENTORS ARTUR VALTER LEOPOLD NORR FRITZ BERTIL WILLY HOLM m 32592 ATTORNEYS United States Patent 3,654,085 STORAGE DEVICE FOR ORGAN TRANSPLANTS Artur Valter Leopold Norr and Fritz Bertil Willy Holm, Lidingo, Sweden, assignors to AGA Aktiebolag, Lidingo, Sweden Filed Nov. 17, 1969, Ser. No. 877,217 Claims priority, application Sweden, Nov. 26, 1968, 16,077/ 68 Int. Cl. A61b 19/00 U.S. Cl. 195-127 3 Claims ABSTRACT OF THE DISCLOSURE A pressure chamber for storing organic transplants and supplying them With oxygenated blood is provided with an oxygenator and a blood pump in the chamber. The pump is driven from a motor outside the chamber so as to avoid pressure influence on the blood, a pressuretight transmission connecting the motor with the pump through the chamber wall.

BACKGROUND OF THE INVENTION The invention relates to a device for storage and blood perfusion of an organic transplant.

This type of storage requires a continuous supply of oxygenated blood to the transplant in order to keep it in fresh condition. An oxygenator is provided in the chamber and a blood pump is also necessary to collect blood from the oxygenator and supply it to the transplant, which may be a heart or a liver or some other organ.

If, in a chamber of the type referred to, the blood pump is placed outside the chamber, lead-through conduits for the perfusion blood are required from the interior of the chamber to the pump and from the latter back into the chamber. This requires the blood to overcome the pressure differential between the outside and the interior of the chamber and a corresponding amount of energy must be supplied by the pump. Also, there is an increased danger of haemolysis of the blood.

SUMMARY OF THE INVENTION It is an object of the invention to provide a storage device which obviates the disadvantage referred to. The characteristic feature of the invention consists in that the blood pump is located in the chamber, whereas the motor is placed outside it, a transmission being provided for connecting the motor with the pump through the wall of the chamber in an air-tight manner.

THE DRAWING The attached drawing shows an embodiment of the invention.

DESCRIPTION OF EMBODIMENT The storage device comprises a chamber having a cylindrical wall V with a window F provided therein for observation of the interior of the chamber. Inserted in the chamber is a container B which is supported by a plate S. The plate S rests on guides SK, on which container B can be pushed into or pulled out of the chamber. The container has a lid, in which a window F is provided in a position corresponding to that of window F. The organic transplant is indicated by L and the artery A thereof is connected via a lead-through at G to a tube SL, which connects the same with the outlet of a blood pump BP. The blood issuing from transplant L flows into an oxygenator OX, from which a conduit L' leads to the inlet of blood pump BP. The axle AX of blood pump BP is brought out through the chamber wall via a bushing H to connect with a motor M. Also, placed outside the chamber is a pump P for supplying oxygen or air to the chamber under increased pressure via conduits R and lead-throughs G and. G".

Owing to the fact that the pressure gas is supplied via lead-through G" to container B there is a direct supply of fresh air or oxygen to the transplant.

The arrangement of blood pump BP within the chamber removes the drawbacks referred to above, which are present if the blood, is to be brought out of the chamber and back after passage through the pump. There is less energy required to be supplied by the pump and the danger of haemolysis is substantially reduced. This advantage is particularly noticeable in connection with a blood pump of a type known per se comprising elastic tubing which is compressed by rotating rollers moving over the tubing for feeding the blood.

The lead-through H referred to above may be of any known type which is capable of withstanding a pressure of about 5 to 10 at.

The pump P can be replaced by some other type of gas supply, such as a container for gas under increased pressure.

We claim:

1. A device for the storage and blood perfusion of organic transplants comprising:

a chamber capable of holding gas under increased pressure,

means for supporting an organ in said chamber,

a pump device in said chamber for maintaining a stream of blood,

first conduit means for conveying said stream of blood from said pump to said organ,

an oxygenator in said chamber positioned to receive blood from said organ,

second conduit means for conveying blood from said oxygenator to said pump,

a motor outside of said chamber for driving said pump, and

a transmission member connecting said motor with said pump device through the wall of said chamber in an airtight manner.

2. A device as claimed in claim 1, in which said pump device comprises a flexible tube and rollers movable along said tube and compressing the same.

3. A device as claimed in claim 1, which includes a support for holding a transplant slidable in said chamber and supporting said oxygenator.

References Cited UNITED STATES PATENTS 1(1/ 1968 Swenson et al. 62--306 12/1970 Swenson et al. 62-231 OTHER REFERENCES A. LOUIS MONACELL, Primary Examiner R. B. ANDEWELT, Assistant Examiner U.S. Cl. X.R.

l28--Heart-Lung Digest

Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3777507 *Nov 24, 1971Dec 11, 1973Waters Instr IncRenal preservation system
US4837390 *May 11, 1983Jun 6, 1989Keyes Offshore, Inc.Storage in perfusate nutrient liquid
US6673594Aug 25, 2000Jan 6, 2004Organ Recovery SystemsPortable hermetically-sealed housing configured to be received by organ perfusion device
US7572622Aug 14, 2003Aug 11, 2009Transmedic, Inc.Apparatus which allows heart to continue beating and pumping blood through all of its chambers and vessels during heart surgery
US7678563Apr 2, 2004Mar 16, 2010Organ Recovery Systems, Inc.Organ perfusion device for monitoring, sustaining and/or restoring viability of organs and for the preserve of organs for storage and/or transport
US7691622Apr 2, 2004Apr 6, 2010Lifeline Scientific, Inc.Method and apparatus for transferring heat to or from an organ or tissue container
US7749693Feb 2, 2004Jul 6, 2010Lifeline Scientific, Inc.Perfusing organ with immunotoxin and monitoring effects; sustaining and/or restoring viability of organs and preserving organs for storage and/or transport
US7824848Jul 11, 2003Nov 2, 2010Lifeline Scientific, Inc.Organ perfusion device for sustaining, restoring viability, storage, transport and preservation of tissues
US7998725Apr 2, 2004Aug 16, 2011Organ Recovery SystemsMethod and apparatus for holding a plurality of tubes connectible to an organ or tissue container
US8097449Feb 16, 2010Jan 17, 2012Organ Recovery SystemsMethod and apparatus for transferring heat to or from an organ or tissue container
US8128740Apr 2, 2004Mar 6, 2012Organ Recovery Systems, Inc.Device for separating gas from a liquid path
US8268547Oct 25, 2005Sep 18, 2012Lifeline Scientific, Inc.Method of transporting and storing a kidney
US8268612Aug 10, 2011Sep 18, 2012Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8318415Oct 22, 2010Nov 27, 2012Lifeline Scientific, Inc.Method of determining transport and/or storage parameters for maintaining viability of an organ
US8323954Mar 29, 2011Dec 4, 2012Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8349551Nov 5, 2010Jan 8, 2013Lifeline Scientific, Inc.Method for controlling perfusion of an organ
US8361091Aug 25, 2003Jan 29, 2013Organ Recovery Systems, Inc.Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US8389271Dec 31, 2009Mar 5, 2013Organ Recovery Systems, Inc.Method and apparatus for controlling air pressure in an organ or tissue container
US8420381Nov 5, 2010Apr 16, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8431385Jan 21, 2011Apr 30, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8445260Aug 10, 2011May 21, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8609400May 12, 2010Dec 17, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8822203Sep 28, 2010Sep 2, 2014Transmedics, Inc.Systems and methods for ex vivo organ care
US8828034Apr 29, 2011Sep 9, 2014Lifeline Scientific, Inc.Cannula
U.S. Classification435/284.1
International ClassificationA01N1/00, A01N1/02
Cooperative ClassificationA01N1/0205, A01N1/02
European ClassificationA01N1/02, A01N1/02C