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Publication numberUS3656185 A
Publication typeGrant
Publication dateApr 18, 1972
Filing dateFeb 4, 1970
Priority dateFeb 4, 1969
Also published asCA930503A1, DE2005112A1, DE2005112B2, DE2005112C3
Publication numberUS 3656185 A, US 3656185A, US-A-3656185, US3656185 A, US3656185A
InventorsCarpentier Alain F
Original AssigneeRhone Poulenc Sa
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Cardiac valvular support prosthesis
US 3656185 A
Abstract
A cardiac valvular prosthesis, e.g., for the mitral valve, consisting solely of an annular or part-annular member adapted to fit against the base of the cusps of a human heart valve, and suture means for securing the member in place. The prosthesis cooperates with the natural valve cusps of the patient to form the valve.
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United States Patent Carpentier [54] CARDIAC VALVULAR SUPPORT PROSTHESIS [72] Inventor: Alain F. Carpentier, Paris, France [73] Assignee: Rhone-Poulenc S.A., Paris, France [22] Filed: Feb. 4, 1970 [2]] Appl. No.: 8,564

[30] Foreign Application Priority Data Feb. 4, 1969 France ..690244l Dec. 19, 1969 France ..6944124 [52] US. Cl "3/15 128534 R [5 1] Int. Cl. ..A61f 1/24 [58] Field olSearch ..3/l,DIG. 3; 128/334 R,1

[56] References Cited UNITED STATES PATENTS 3,396,409 8/1968 Meirose ..3/l

' OTHER PUBLICATIONS A Prosthetic Stented Aortic Homograft For Mitral Valve Replacement Q. S. Weldon et al., Journal of Surgical [151 3,656,185 [451 Apr. 18, 1972 Research, Vol. 6, No. 12, Dec. 1966, pgs. 548.- 552 Simplified Insertion of Aortic Homograft Valves With Nonthrombogenic Prosthetic Frames by Nina S. Braunwald et al., Transaction American Soc. For Artificial Internal 0rgans, vol. XIII, 1967, pgs. 1 l l- 113 The In Vivo Comparison of Hemodynamic Function of Bali, Disk, and Eccentric Monocusp Artifial IMitral Valves" by R. W. M. Frater et al., Prosthetic Heart Valves, Charles C. ThomasPublisher, Springfield, Illinois, I 968, pgs. 262- 266 Primary Examiner-Dalton L. Truluck Assistant Examiner-Ronald L. Frinks Attorney-Stevens, Davis, Miller & Mosher [57] ABSTRACT A cardiac valvular prosthesis, e.g., for the mitral valve, consisting solely of an annular or part-annular member adapted to fit against the base of the cusps of a human heart valve, and suture means for securing the member in place. The prosthesis cooperates with the natural valve cusps of the patient to form the valve.

6 Claims, 6 Drawing Figures PATENTEUAPR 18 1912 SHEET 1 OF 2 inventor V ALAIN CARPENTIER Attorney! PATENTEUAPR 18 1972 3,656,185

sum 2 [IF 2 Inventor BY ALAIN CARPENTIER mwws M Attorneys CARDIAC VALVULAR SUPPORT PROSTHESIS The present invention relates to a prosthesis intended for the surgical correction of valvular diseases and notably diseases affecting the mitral valve.

In the case of mitral disease, it is known to preserve the natural cusps of a valve and to correct the defects therein. However, Kays annuloplasty, Woolers asymmetrical annuloplasty and Reeds annuloplasty give uncertain results, because leakage may persist. In addition, the mitral ring may continue to distend and the stitches made in the commissuroplasty may yield under the action of the tensile forces to which they are subjected. This results in a reduction in the efficiency of the valve with a frequency which is given as to 40 percent by the authors.

It is also known, in order to obviate valvular deformation, especially mitral valve deformation, to proceed with ablation of the defective cusps and to replace them by a prosthesis.

Such a prosthesis is described in US. Pat. No. 3,374,489 and includes an annular member which is inserted into the mitral ring and a valve disc provided with hooks, the disc oscillating between two extreme positions and alternately opening and closing the mitral orifice. The annular member performs the double function of retaining the valve disc and constituting the valve seat.

Such a prosthesis has various disadvantages, in that it interferes with the normal physiology of the mitral apparatus, it necessitates the prolonged use of anticoagulants and it may cause a thrombosis or a sudden mechanical defect.

According to the present invention, there is provided a cardiac valvular prosthesis consisting solely of an annular or partannular member adapted to fit against the base of the cusps of a human heart valve, and suture means for securing the member in place. With such a prosthesis the natural valve cusps are retained, and the prosthesis is inserted at the base thereof.

The annular or part-annular member may consist of a rigid frame, suture means and a textile sheath enclosing the frame and suture means.

The invention will be more readily understood from the following description, given merely by way of example reference being made to the accompanying drawings, in which:

FIG. 1 is an elevation of one embodiment of prosthesis according to the invention;

FIG. 2 is a section taken along the line AA, of FIG. 1, and drawn to a large scale;

FIG. 3 is a view of the mitral valve in the course of the positioning of the prosthesis of FIG. 1;

FIG. 4 is a view of the mitral valve after the positioning of the prosthesis of FIG. 1;

FIG. 5 is an elevation of a second embodiment of prosthesis according to the invention; and

FIG. 6 is a view of the mitral valve after the the prosthesis according to FIG. 5.

The prosthesis shown in FIG. 1 closely follows the form of the base of the valve cusps and it has substantially the form of a closed ring 1, which is plane, circular, oval or, as shown, slightly flattened at 2 over a length between one-quarter and one-half of its periphery. Substantially straight portion 2 corresponds to the curvature of the large cusp and the complementary zone corresponds to the curvature of the small cusp. The ring has in its plane an axis of symmetry, its largest dimensions, along this axis and along a perpendicular axis, being generally between and 30 mm. and and 40 mm. respectively.

As seen in FIG. 2, the ring comprises a rigid frame}, for example of stainless steel. This frame is light since it has an asymmetric, outwardly hollow channel section defining an extemal groove. The flanges of the channel section are of unequal widths, the lower edge 4, which is flat being narrower positioning of and intended to rest on the mitral ring, while the upper flange 5 has a rounded profile. The width of the lower flange is generally between 0.5 and 2 mm. and that of the upper flange between I and 3 mm. This arrangement makes it possible for the suture stitches to be automatically embedded.

Within the groove is disposed a stitchable cord 6, which is maintained within the groove by a filament 8 of large caliber, formed for example of polytetrafluorethylene. The ring also comprises a woven textile sheath 7, for example also of polytetrafluorethylene, which simultaneously encloses or covers the frame 3 and the cord 6.

A prosthesis according to the invention may be made from any inert materials which are well tolerated by the organism and have appropriate strength, and stainless steel and polytetrafluorethylene have only been referred to by way of example. For example ethyleneglycol polyterephthalate may be used instead of polytetrafluoroethylene.

As seen in FIG. 5 and 6, the prosthesis may be in the form of an open ring, i.e., it may be part of an annulus 1, which is slightly flattened to fit closely against the base of the cusps. This part-annulus is open over a length generally between onequarter and one-half of its periphery, so that the space between the free ends is between one-third and one times the peripheral length of the part annular member itself. This length corresponds substantially to the length of the base of the cusp which it is desired to allow to have free movement. In FIGS. 5 and 6, the ring is open over a length equal to one-third of its periphery, this length corresponding substantially to the base of the large cusp 12. The ring thus closely fits against the base of the small cusp 13 and allows the large cusp to have free movement.

The ends 14 and 15 of the ring are rounded in order not to damage the tissues in which they are disposed.

The profile of the ring is similar to that of the construction of FIGS. 1 to 4, i.e., its cross section is as shown in FIG. 2. Thus, it has an external groove, the lower flange intended to rest on the mitral ring again being plane, while the upper edge has a rounded profile. Situated inside the groove is a largecaliber filament of polytetrafluoroethylene or of ethyleneglycol polyterephthalate, which maintains a stitchable cord within the frame, after having been stretched between the two ends of the frame. For this purpose, the ends of the frame are each formed with a hole, the filament is pulled between these holes and is fused on either side of the holes so as to produce beads, and then released.

The annular mitral prosthesis of FIGS. 1 to 4 is positioned between the left auricle and the left ventricle by the surgical technique described below with reference to FIGS. 3 and 4.

First of all, the dilatation of the mitral ring is checked, and it is verified that the cusps are sufficiently supple, that the large cusp has sufficient freedom of movement and that there is no lesion of the ligaments by which the large cusp is fixed.

Two appropriate suture filaments l0 and 11 are disposed in U-form and stitched with the aid of a needle into the thickness of the mitral ring, parallel to the latter, at the ends of the large cusp 12. The distance between these two filaments corresponds to the width of the flattened zone 2 of the annular prosthesis and permits of defining the dimension of the prosthesis appropriate for the orifice under consideration.

About 20 filaments constituting as many absolutely equidistant stitches are positioned in the same way between the filaments l0 and 11 and around the whole periphery of the mitral ring, at the base of the cusps and immediately above. These filaments are then passed through the cord of the prosthesis, with an identical spacing for the filaments corresponding to the large cusp and with a reduced spacing for the filaments corresponding to the small cusp 13.

The prosthesis is then slid along the filaments against the mitral ring and thereafter fixed by knotting the filaments. The knots are substantially invisible and the projection of the prosthesis is insignificant, so that it can be rapidly overlapped and incorporated by the neighboring organic tissues.

The surgical technique of positioning the open ring is similar to that described above.

The described prosthesis permit of treating mitral inadequacies due, for example, to contraction of the large cusp, to

' opening of the commissural curvatures, to distension of the mitral ring in the zone of attachment of the small cusp, and so on. They also permit, after commissurotomy, of treating an orificial stricture due to a fibrous fusion of the commissures.

A prosthesis according to the invention has many advantages other than its simplicity and its safety of use. Owing to its particular form, it permits the preservation and repositioning of the valvular elements, as also the correction of various anomalies. For example, it permits repositioning and development of the large cusp, commissural remodelling, and reduction of the small cusp. Thus, it renders possible recontacting of the cusps in a mitral orifice of normal surface. The open ring prosthesis permits free movement of one of the cusps of a valve, notably the free movement of the large cusp in the mitral valve. In addition, owing to the rigid frame it is possible to distribute the tractive forces over a large number of points and to counteract secondary distension of the mitral ring. Finally, owing to the woven sheath to which the fibrin can adhere, it is rapidly incorporated in the tissues and therefore requires no prolonged anticoagulant treatment and involves no danger of thrombosis.

Although only two particular embodiments of mitral prosthesis have been described by way of example, a prosthesis according to the invention may undergo various modifications of construction and may readily be adapted to other valves, notably to the tricuspid valve, by using a ring of the same type, of circular form, or to the aortic valve by using a ring adapted to the trifoliate form of the aortic valvular orifice.

Iclaim:

l. A cardiac valve support for supporting the cusps of a natural human heart valve without excising said valve and cusps, consisting solely of: an elongated member curved along its length to define a generally ring-shaped rigid member of a size and shape to fit against the base of the cusps of a natural human heart valve, the central axis of said curved elongated member lying substantially in a single plane, and suture means for suturing the member in place, said suture means being substantially coextensive with said elongated member.

2. A cardiac valve support as claimed in claim 1, wherein the elongated member comprises a rigid frame, and wherein said frame and suture means are enclosed in a textile sheath.

3. A cardiac valve support as claimed in claim 2, wherein said frame comprises an asymmetric, outwardly hollow, channel section having unequal length flanges defining an external groove, and said suture means comprises a suturable cord disposed within said external groove.

4. A cardiac valve support as claimed in claim 3, wherein a reinforcing filament extends along said elongated member within said cord.

5. A cardiac valve support as claimed in claim 1, wherein said elongated member is curved in an annular shape, including a circular sector portion and a substantially straight portion together defining the annular periphery of said elongated member, said straight portion comprising between onequarter and one-half of said periphery.

6. A cardiac valve support as claimed in claim 1, wherein said member is a part-annular member curved in an annular shape but omitting between one-quarter and one-half of the total peripheral length of said total annular shape, said partannular member having spaced apart ends, the annular arcuate spacing between said ends being not less than about one third of the actual peripheral length of said part-annular member.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US3396409 *Dec 9, 1965Aug 13, 1968Nat Res DevArtificial heart valve
Non-Patent Citations
Reference
1 * A Prosthetic Stented Aortic Homograft For Mitral Valve Replacement by C. S. Weldon et al., Journal of Surgical Research, Vol. 6, No. 12, Dec. 1966, pgs. 548 552
2 * Simplified Insertion of Aortic Homograft Valves With Nonthrombogenic Prosthetic Frames by Nina S. Braunwald et al., Transaction American Soc. For Artificial Internal Organs, vol. XIII, 1967, pgs. 111 113
3 * The In Vivo Comparison of Hemodynamic Function of Ball, Disk, and Eccentric Monocusp Artifial Mitral Valves by R. W. M. Frater et al., Prosthetic Heart Valves, Charles C. Thomas Publisher, Springfield, Illinois, 1968, pgs. 262 266
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3908201 *Jun 8, 1973Sep 30, 1975Ici LtdProsthetics
US4042978 *Jun 11, 1975Aug 23, 1977Imperial Chemical Industries LimitedProsthetics
US4042979 *Jul 12, 1976Aug 23, 1977Angell William WValvuloplasty ring and prosthetic method
US4055861 *Apr 9, 1976Nov 1, 1977Rhone-Poulenc IndustriesSupport for a natural human heart valve
US4164046 *May 16, 1977Aug 14, 1979Cooley DentonValve prosthesis
US4204283 *May 3, 1978May 27, 1980National Research Development CorporationProsthetic valve
US4217665 *Jun 22, 1976Aug 19, 1980Societe D'utilisation Scientifique Et Industrielle Du Froid - UsifroidProsthesis for use in valvuloplasty
US4290151 *Jul 22, 1980Sep 22, 1981Massana Miguel PAdjustable annular prosthesis for cardiac surgery
US4489446 *Jul 14, 1982Dec 25, 1984Reed Charles CHeart valve prosthesis
US4865600 *Aug 25, 1981Sep 12, 1989Baxter International Inc.Mitral valve holder
US4917698 *Dec 22, 1988Apr 17, 1990Baxter International Inc.Multi-segmented annuloplasty ring prosthesis
US5041130 *Nov 30, 1989Aug 20, 1991Baxter International Inc.Flexible annuloplasty ring and holder
US5061277 *Sep 2, 1988Oct 29, 1991Baxter International Inc.Flexible cardiac valvular support prosthesis
US5104407 *Sep 20, 1990Apr 14, 1992Baxter International Inc.Selectively flexible annuloplasty ring
US5258023 *Feb 12, 1992Nov 2, 1993Reger Medical Development, Inc.Prosthetic heart valve
US5350420 *May 25, 1993Sep 27, 1994Baxter International Inc.Flexible annuloplasty ring and holder
US5415667 *Jun 4, 1991May 16, 1995Frater; Robert W. M.Mitral heart valve replacements
US5562729 *Nov 1, 1994Oct 8, 1996Biocontrol Technology, Inc.Heart valve
US5607471 *Aug 21, 1995Mar 4, 1997Jacques SeguinProsthetic ring for heart surgery
US5674279 *Jun 29, 1995Oct 7, 1997Medtronic, Inc.Annuloplasty and suture rings
US5776189 *Mar 5, 1997Jul 7, 1998Khalid; NaqeebCardiac valvular support prosthesis
US5824066 *May 21, 1997Oct 20, 1998Medtronic, Inc.Annuloplasty prosthesis
US6024096 *May 1, 1998Feb 15, 2000Correstore IncAnterior segment ventricular restoration apparatus and method
US6102945 *Oct 16, 1998Aug 15, 2000Sulzer Carbomedics, Inc.Separable annuloplasty ring
US6143024 *Jun 4, 1998Nov 7, 2000Sulzer Carbomedics Inc.Annuloplasty ring having flexible anterior portion
US6174332Dec 5, 1997Jan 16, 2001St. Jude Medical, Inc.Annuloplasty ring with cut zone
US6221104Jan 22, 1999Apr 24, 2001Cor Restore, Inc.Anterior and interior segment cardiac restoration apparatus and method
US6231602Apr 16, 1999May 15, 2001Edwards Lifesciences CorporationAortic annuloplasty ring
US6254636Jun 26, 1998Jul 3, 2001St. Jude Medical, Inc.Single suture biological tissue aortic stentless valve
US6283993May 27, 1998Sep 4, 2001Edwards Lifesciences CorporationAnnuloplasty ring delivery system
US6306133Oct 2, 1999Oct 23, 2001Quantum Cor IncorporatedAblation catheter system and methods for repairing a valvular annulus
US6312464Apr 28, 1999Nov 6, 2001NAVIA JOSť L.Method of implanting a stentless cardiac valve prosthesis
US6348068Jul 23, 1999Feb 19, 2002Sulzer Carbomedics Inc.Multi-filament valve stent for a cardisc valvular prosthesis
US6406492Apr 8, 1999Jun 18, 2002Sulzer Carbomedics Inc.Annuloplasty ring holder
US6439237Jan 11, 2000Aug 27, 2002Correstore, Inc.Anterior segment coronary restoration apparatus and method
US6450171Oct 11, 2000Sep 17, 2002Correstore, Inc.Anterior and inferior segment ventricular restoration apparatus and method
US6485489Mar 19, 2002Nov 26, 2002Quantum Cor, Inc.Catheter system for repairing a mitral valve annulus
US6524338Aug 25, 2000Feb 25, 2003Steven R. GundryMethod and apparatus for stapling an annuloplasty band in-situ
US6544167May 17, 2001Apr 8, 2003Correstore, Inc.Ventricular restoration patch
US6558416Mar 6, 2001May 6, 2003Edwards Lifesciences CorporationAnnuloplasty ring delivery method
US6558417Jul 2, 2001May 6, 2003St. Jude Medical, Inc.Single suture biological tissue aortic stentless valve
US6569198Mar 30, 2001May 27, 2003Richard A. WilsonMitral or tricuspid valve annuloplasty prosthetic device
US6602289 *Jun 8, 1999Aug 5, 2003S&A Rings, LlcAnnuloplasty rings of particular use in surgery for the mitral valve
US6669725Dec 28, 2000Dec 30, 2003Centerpulse Biologics Inc.Annuloplasty ring for regeneration of diseased or damaged heart valve annulus
US6689163Mar 28, 2002Feb 10, 2004Carbomedics Inc.Annuloplasty ring holder
US6730121May 14, 2002May 4, 2004MedtentiaAnnuloplasty devices and related heart valve repair methods
US6749630Aug 28, 2001Jun 15, 2004Edwards Lifesciences CorporationTricuspid ring and template
US6802860Apr 8, 2003Oct 12, 2004Edwards Lifesciences CorporationAnnuloplasty ring delivery system
US6837247Apr 8, 2003Jan 4, 2005Correstore, Inc.Method of using ventricular restoration patch
US6908482May 3, 2002Jun 21, 2005Edwards Lifesciences CorporationThree-dimensional annuloplasty ring and template
US6918917Oct 10, 2000Jul 19, 2005Medtronic, Inc.Minimally invasive annuloplasty procedure and apparatus
US6921407Apr 10, 2002Jul 26, 2005Medtronic, Inc.Minimally invasive annuloplasty procedure and apparatus
US6964684Feb 26, 2004Nov 15, 2005MedtentiaAnnuloplasty devices and related heart valve repair methods
US7033390Jan 2, 2003Apr 25, 2006Medtronic, Inc.Prosthetic heart valve system
US7056280Aug 7, 2002Jun 6, 2006Correstore, Inc.Anterior segment ventricular restoration apparatus and method
US7066954Mar 3, 2004Jun 27, 2006Medtronic, Inc.Annuloplasty system
US7077861Nov 19, 2004Jul 18, 2006Medtentia AbAnnuloplasty instrument
US7077862Jun 15, 2004Jul 18, 2006Myocor, Inc.Devices and methods for heart valve treatment
US7112219Nov 10, 2003Sep 26, 2006Myocor, Inc.Devices and methods for heart valve treatment
US7118595Jun 19, 2002Oct 10, 2006Medtronic, Inc.Flexible annuloplasty prosthesis and holder
US7122043May 19, 2004Oct 17, 2006Stout Medical Group, L.P.Tissue distention device and related methods for therapeutic intervention
US7189199May 2, 2002Mar 13, 2007Myocor, Inc.Methods and devices for improving cardiac function in hearts
US7189258Apr 25, 2002Mar 13, 2007Medtronic, Inc.Heart valve system
US7220277Mar 20, 2003May 22, 2007Sorin Biomedica Cardio S.P.A.Prosthesis for annuloplasty comprising a perforated element
US7229469Apr 26, 2003Jun 12, 2007Quantumcor, Inc.Methods for treating and repairing mitral valve annulus
US7247134Nov 10, 2003Jul 24, 2007Myocor, Inc.Devices and methods for heart valve treatment
US7275546Mar 29, 2004Oct 2, 2007Buckberg Gerald DAnterior and inferior segment ventricular restoration apparatus and method
US7276079Jul 13, 2004Oct 2, 2007Medos Medizintechnik AgImplant with an annular base
US7294148Apr 29, 2004Nov 13, 2007Edwards Lifesciences CorporationAnnuloplasty ring for mitral valve prolapse
US7367991Jun 14, 2004May 6, 2008Edwards Lifesciences CorporationConformal tricuspid annuloplasty ring and template
US7371259Sep 20, 2005May 13, 2008Medtronic, Inc.Annuloplasty band and method
US7377940Aug 13, 2004May 27, 2008Medtronic, Inc.Implantable prosthesis
US7452376May 10, 2005Nov 18, 2008St. Jude Medical, Inc.Flexible, non-planar annuloplasty rings
US7468073Apr 11, 2006Dec 23, 2008Medtronic, Inc.Heart valve system
US7476247Apr 11, 2006Jan 13, 2009Medtronic, Inc.Flexible annuloplasty prosthesis and holder
US7503929Jan 23, 2006Mar 17, 2009Medtronic, Inc.Prosthetic heart valve system
US7547313May 16, 2003Jun 16, 2009Medtronic, Inc.Tissue connector apparatus and methods
US7575595Mar 22, 2006Aug 18, 2009Edwards Lifesciences CorporationAnnuloplasty ring and holder combination
US7594886Jan 3, 2005Sep 29, 2009Correstore LlcMethod of using ventricular restoration patch
US7637944Apr 26, 2006Dec 29, 2009Medtronic, Inc.Annuloplasty system
US7648532Jan 3, 2006Jan 19, 2010Septrx, Inc.Tissue distention device and related methods for therapeutic intervention
US7666224Jul 7, 2005Feb 23, 2010Edwards Lifesciences LlcDevices and methods for heart valve treatment
US7678145Jul 1, 2005Mar 16, 2010Edwards Lifesciences LlcDevices and methods for heart valve treatment
US7695425Feb 17, 2004Apr 13, 2010Edwards Lifesciences LlcHeart wall tension reduction apparatus and method
US7722523Jul 9, 2002May 25, 2010Edwards Lifesciences LlcTransventricular implant tools and devices
US7722643Jul 29, 2002May 25, 2010Medtronic, Inc.Tissue connector apparatus and methods
US7744611Nov 19, 2003Jun 29, 2010Medtronic, Inc.Minimally invasive valve repair procedure and apparatus
US7758494Jun 5, 2006Jul 20, 2010Correstore, Inc.Anterior segment ventricular restoration apparatus and method
US7758638Aug 29, 2007Jul 20, 2010Ats Medical, Inc.Implant with an annular base
US7763040Feb 10, 2003Jul 27, 2010Medtronic, Inc.Tissue connector apparatus and methods
US7766812Apr 14, 2006Aug 3, 2010Edwards Lifesciences LlcMethods and devices for improving mitral valve function
US7842085Sep 1, 2006Nov 30, 2010Vaso AdzichAnnuloplasty ring and holder combination
US7879047Dec 10, 2003Feb 1, 2011Medtronic, Inc.Surgical connection apparatus and methods
US7879087 *Oct 5, 2007Feb 1, 2011Edwards Lifesciences CorporationMitral and tricuspid annuloplasty rings
US7883538Sep 20, 2005Feb 8, 2011Guided Delivery Systems Inc.Methods and devices for termination
US7883539Apr 23, 2002Feb 8, 2011Edwards Lifesciences LlcHeart wall tension reduction apparatus and method
US7892255Aug 28, 2003Feb 22, 2011Medtronic, Inc.Tissue connector apparatus and methods
US7896892Apr 3, 2003Mar 1, 2011Medtronic, Inc.Multiple bias surgical fastener
US7914438Sep 28, 2009Mar 29, 2011Correstore LlcVentricular restoration patch
US7914544Dec 7, 2004Mar 29, 2011Medtronic, Inc.Minimally invasive valve repair procedure and apparatus
US7922762Jun 3, 2008Apr 12, 2011Guided Delivery Systems Inc.Devices and methods for cardiac annulus stabilization and treatment
US7935145 *Jun 30, 2004May 3, 2011Edwards Lifesciences CorporationAnnuloplasty ring for ischemic mitral valve insuffuciency
US7938840Nov 18, 2003May 10, 2011Medtronic, Inc.Apparatus and methods for anastomosis
US7938856May 10, 2005May 10, 2011St. Jude Medical, Inc.Heart valve annuloplasty prosthesis sewing cuffs and methods of making same
US7951196Feb 2, 2006May 31, 2011Edwards Lifesciences CorporationAnnuloplasty ring for mitral valve prolapse
US7959673Sep 11, 2008Jun 14, 2011Edwards Lifesciences CorporationDegenerative valvular disease specific annuloplasty rings
US7963973Sep 2, 2005Jun 21, 2011Medtronic, Inc.Multiple loop tissue connector apparatus and methods
US7976556Dec 21, 2006Jul 12, 2011Medtronic, Inc.Anastomosis apparatus and methods
US7981020Jun 5, 2008Jul 19, 2011Edwards Lifesciences LlcTransventricular implant tools and devices
US7988725Jun 15, 2009Aug 2, 2011Valtech Cardio, Ltd.Segmented ring placement
US7993393Sep 10, 2009Aug 9, 2011Edwards Lifesciences CorporationFlexible heart valve and associated connecting band
US7993395Jan 22, 2009Aug 9, 2011Medtronic, Inc.Set of annuloplasty devices with varying anterior-posterior ratios and related methods
US7993396Sep 21, 2009Aug 9, 2011Edwards Lifesciences CorporationMitral valve annuloplasty ring having an offset posterior bow
US8007530Apr 26, 2006Aug 30, 2011Medtronic, Inc.Tool and method for implanting an annuloplasty prosthesis
US8029519Sep 14, 2006Oct 4, 2011Medtronic, Inc.Eversion apparatus and methods
US8029564Feb 17, 2009Oct 4, 2011Medtronic, Inc.Prosthetic heart valve system
US8034103Dec 28, 2006Oct 11, 2011Sorin Biomedica Cardio S.R.L.Annuloplasty prosthesis with an auxetic structure
US8048152Apr 26, 2006Nov 1, 2011Medtronic, Inc.Method of implanting an annuloplasty prosthesis
US8052748May 12, 2005Nov 8, 2011St. Jude Medical, Inc.Systems and methods for holding annuloplasty rings
US8066724Jan 10, 2003Nov 29, 2011Medtronic, Inc.Anastomosis apparatus and methods
US8066766Aug 20, 2007Nov 29, 2011Guided Delivery Systems Inc.Methods and devices for termination
US8070805Jan 25, 2010Dec 6, 2011Edwards Lifesciences LlcDevices and methods for heart valve treatment
US8092367May 16, 2008Jan 10, 2012Mardil, Inc.Method for external stabilization of the base of the heart
US8096985May 7, 2009Jan 17, 2012Guided Delivery Systems Inc.Deflectable guide
US8105345Jan 10, 2003Jan 31, 2012Medtronic, Inc.Anastomosis apparatus and methods
US8114155Apr 14, 2008Feb 14, 2012Edwards Lifesciences CorporationAnnuloplasty ring with offset free ends
US8118822Apr 5, 2001Feb 21, 2012Medtronic, Inc.Bridge clip tissue connector apparatus and methods
US8123800Apr 14, 2005Feb 28, 2012Edwards Lifesciences CorporationThree-dimensional annuloplasty ring and template
US8128553Dec 12, 2006Mar 6, 2012Mardil, Inc.Method and apparatus for external stabilization of the heart
US8142495May 15, 2007Mar 27, 2012Edwards Lifesciences AgSystem and a method for altering the geometry of the heart
US8152844May 7, 2009Apr 10, 2012Edwards Lifesciences CorporationQuick-release annuloplasty ring holder
US8177836Mar 10, 2009May 15, 2012Medtronic, Inc.Apparatus and methods for minimally invasive valve repair
US8197538May 31, 2007Jun 12, 2012Medtronic, Inc.Annuloplasty prosthesis with in vivo shape identification and related methods of use
US8206439Feb 22, 2005Jun 26, 2012International Heart Institute Of Montana FoundationInternal prosthesis for reconstruction of cardiac geometry
US8211124Feb 5, 2007Jul 3, 2012Medtronic, Inc.Sealing clip, delivery systems, and methods
US8211131Apr 5, 2011Jul 3, 2012Medtronic, Inc.Apparatus and methods for anastomosis
US8216304May 24, 2010Jul 10, 2012Edwards Lifesciences CorporationAnnuloplasty ring and holder combination
US8226711Jul 1, 2005Jul 24, 2012Edwards Lifesciences, LlcValve to myocardium tension members device and method
US8236050Dec 18, 2007Aug 7, 2012Edwards Lifesciences CorporationMitral annuloplasty ring having upward bows
US8267852Jul 8, 2010Sep 18, 2012Edwards Lifesciences, LlcHeart wall tension reduction apparatus and method
US8273118Sep 16, 2008Sep 25, 2012Medtronic, Inc.Heart valve holder assembly for use in valve implantation procedures
US8287555Dec 19, 2003Oct 16, 2012Guided Delivery Systems, Inc.Devices and methods for heart valve repair
US8287557Aug 20, 2007Oct 16, 2012Guided Delivery Systems, Inc.Methods and devices for termination
US8287591Sep 19, 2008Oct 16, 2012Edwards Lifesciences CorporationTransformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation
US8298251Feb 27, 2008Oct 30, 2012Medtronic, Inc.Anastomosis apparatus and methods
US8328798May 15, 2007Dec 11, 2012Quantumcor, IncMethod for treating and repairing mitral valve annulus
US8343173Jun 4, 2008Jan 1, 2013Guided Delivery Systems Inc.Delivery devices and methods for heart valve repair
US8353092Feb 7, 2011Jan 15, 2013Medtronic, Inc.Multiple bias surgical fastener
US8353921Aug 4, 2010Jan 15, 2013Medtronic, IncTissue connector apparatus and methods
US8353956Feb 17, 2010Jan 15, 2013Valtech Cardio, Ltd.Actively-engageable movement-restriction mechanism for use with an annuloplasty structure
US8382828Dec 22, 2010Feb 26, 2013Edwards Lifesciences CorporationMitral annuloplasty rings
US8388680Oct 18, 2006Mar 5, 2013Guided Delivery Systems, Inc.Methods and devices for catheter advancement and delivery of substances therethrough
US8394114Sep 26, 2003Mar 12, 2013Medtronic, Inc.Surgical connection apparatus and methods
US8449608Jan 20, 2011May 28, 2013Edwards Lifesciences CorporationTricuspid ring
US8460173Sep 11, 2012Jun 11, 2013Edwards Lifesciences, LlcHeart wall tension reduction apparatus and method
US8506624Dec 2, 2011Aug 13, 2013Edwards Lifesciences, LlcDevices and methods for heart valve treatment
US8518060Apr 9, 2009Aug 27, 2013Medtronic, Inc.Medical clip with radial tines, system and method of using same
US8529583Mar 31, 2000Sep 10, 2013Medtronic, Inc.Surgical clip removal apparatus
US8529620Apr 29, 2008Sep 10, 2013Ottavio AlfieriInwardly-bowed tricuspid annuloplasty ring
US8529621 *Mar 9, 2012Sep 10, 2013Edwards Lifesciences CorporationMethods of repairing an abnormal mitral valve
US8568473Dec 15, 2006Oct 29, 2013Georgia Tech Research CorporationSystems and methods for enabling heart valve replacement
US8568476Mar 22, 2012Oct 29, 2013Edwards Lifesciences CorporationMethods of assembling and delivering a cardiac implant
US8579798Jun 5, 2008Nov 12, 2013Edwards Lifesciences, LlcExternal cardiac stress reduction method
US8591576Feb 14, 2012Nov 26, 2013Edwards Lifesciences AgMethod for altering the geometry of the heart
US8641727Jun 3, 2008Feb 4, 2014Guided Delivery Systems, Inc.Devices and methods for heart valve repair
US8668704Apr 24, 2009Mar 11, 2014Medtronic, Inc.Medical clip with tines, system and method of using same
US8685083Jun 26, 2006Apr 1, 2014Edwards Lifesciences CorporationApparatus, system, and method for treatment of posterior leaflet prolapse
US8715160Feb 6, 2012May 6, 2014Mardil, Inc.Method and apparatus for external stabilization of the heart
US8758395Jul 19, 2005Jun 24, 2014Septrx, Inc.Embolic filtering method and apparatus
US8764821Mar 16, 2012Jul 1, 2014Edwards Lifesciences CorporationDegenerative vavlular disease specific annuloplasty ring sets
US8790367Feb 5, 2009Jul 29, 2014Guided Delivery Systems Inc.Multi-window guide tunnel
US8795298Oct 9, 2009Aug 5, 2014Guided Delivery Systems Inc.Tether tensioning devices and related methods
US8795353Jan 23, 2009Aug 5, 2014Medtronic, Inc.Holder devices for annuloplasty devices having a plurality of anterior-posterior ratios
US20120172983 *Mar 9, 2012Jul 5, 2012Edwards Lifesciences CorporationMethods of repairing an abnormal mitral valve
USRE42395 *Oct 12, 2007May 24, 2011Medtronic, Inc.Valve holder for tricuspid heart valve
CN100421632CFeb 1, 2005Oct 1, 2008磊 金Artificial heart valve forming ring
DE10301023A1 *Jan 13, 2003Jul 22, 2004Medos Medizintechnik AgImplant, in particular ring for heart valve, designed in curved and asymmetric shape
EP0338994A1 *Jan 10, 1989Oct 25, 1989Mario MoreaProsthetic device for the surgical correction of tricuspid insufficiency
EP1266641A1Jun 11, 2001Dec 18, 2002SORIN BIOMEDICA CARDIO S.p.A.An annuloplasty prosthesis and a method for its manufacture
EP1913900A1Jun 29, 2004Apr 23, 2008SIEVERS, Hans-Hinrich, Dr.Implant with a ring-shaped base plate
EP2153799A1Mar 27, 2002Feb 17, 2010Sorin Biomedica Cardio S.r.l.A prosthesis for annuloplasty comprising a perforated element
WO1991019465A1 *Jun 4, 1991Dec 26, 1991Robert William Mayo FraterMitral heart valve replacements
WO1995003757A1 *Jul 22, 1994Feb 9, 1995Jacques SeguinProsthetic ring for use in cardiac surgery
WO1995006447A1 *Oct 6, 1993Mar 9, 1995Gore & AssImproved device for tissue repair and method for employing same
WO1999029269A1 *Nov 30, 1998Jun 17, 1999St Jude MedicalAnnuloplasty ring with cut zone
WO2000062715A1Apr 14, 2000Oct 26, 2000Edwards Lifesciences CorpAortic annuloplasty ring
WO2000074603A1 *May 23, 2000Dec 14, 2000S & A Rings LlcAnnuloplasty rings for heart valve replacement and repair
WO2002015798A2Aug 27, 2001Feb 28, 2002Sulzer Carbomedics IncMethod and apparatus for stapling an annuloplasty band in-situ
WO2007040998A1 *Sep 20, 2006Apr 12, 2007Medtronic IncFlexible annuloplasty prosthesis
WO2010070455A1Dec 15, 2009Jun 24, 2010Jean-Paul CouetilAnnuloplasty ring with directional flexibilities and rigidities to assist the mitral annulus dynamics
WO2010070649A1Dec 21, 2009Jun 24, 2010Mor Research Applications Ltd.Elongated body for deployment in a coronary sinus
WO2011033508A1Sep 15, 2010Mar 24, 2011Transcardia Ltd.Heart valve remodeling
Classifications
U.S. Classification623/2.36
International ClassificationA61F2/24
Cooperative ClassificationA61F2/2448
European ClassificationA61F2/24R2D
Legal Events
DateCodeEventDescription
Jan 30, 1990ASAssignment
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Effective date: 19880518
Mar 2, 1987ASAssignment
Owner name: BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE
Free format text: MERGER;ASSIGNOR:AMERICAN HOSPITAL SUPPLY CORPORATION INTO;REEL/FRAME:004760/0345
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Oct 29, 1981ASAssignment
Owner name: SOCIETE DES INDUSTRIES PLASTIQUES-SODIP 7 AVENUE L
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Owner name: SOCIETE DES INDUSTRIES PLASTIQUES-SODIP, FRANCE
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Oct 20, 1980AS02Assignment of assignor's interest
Owner name: AMERICAN HOSPITAL SUPPLY CORPORATON, ONE AERICAN P
Owner name: SOCIETE DES INDUSTRIES PLASTIQUES
Effective date: 19800701