|Publication number||US3693623 A|
|Publication date||Sep 26, 1972|
|Filing date||Dec 25, 1970|
|Priority date||Dec 25, 1970|
|Publication number||US 3693623 A, US 3693623A, US-A-3693623, US3693623 A, US3693623A|
|Inventors||Edwin A Amstutz, Richard A Harte|
|Original Assignee||Gregory System Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (3), Referenced by (218), Classifications (16)|
|External Links: USPTO, USPTO Assignment, Espacenet|
350 3611 7 Ell H United States Pal Harte et al. 5] Sept. 26, 1972  PHOTOCOAGULATION MEANS AND  References Cited 4 METHOD FOR DEPILATION UNITED STATES PATENTS  Inventors: Richard A. Harte, Redwood City;
Edwin A, Amstutz Santa Clara, l 1/1970 Meyer 128/398 bOth Of Calif. 3,471,215 10/1969 snitzel' 128/398 X Assignee: g y y Inc. Houston Tex- 3,327,712 6/1967 Kaufrnan et al. 128/393 I Filed! 1970 Primary Examiner-Lawrence W. Trapp [2!] Appl NM 92598 Attorney-Laurence R. Brown i Related U.S. Application Data 57 ABSTRACT Continuation-impart 0f March Depilation is effected by use of light energy of a 1970, abandofledselected frequency band concentrated into a flexible fiber small enough to enter the region of the follicle. "123/3031, 128/355, 128/398 This effects photocoagulation tissue in a limited region [51 1 int. "A61l' d t rmined the placement of the fiber  Field Of Search ..l23/303.l, 398, 303.18, 355
20 Claims, 3 Drawing Figures XENO N AF C PULSE D POWER SUPPLY -'SHEET 1 UF 2 XENOIN AFC POWER SUPPLY 7 K PULSED INVENTORS Richard Hay-Tc, Edwin AmSt vdiz ATTORNEY PATEMEfisms m2 SHEET 2 OF 2 INVENTOR RICHARD A HARTE ED IN A. AMSTU ATTORNEY PHOTOCOAGULATION MEANS AND METHOD FOR DEPILATION This application is a continuation-in-part of the copending abandoned application Ser. No. 23,921 filed Mar. 30, 1970. I
This invention relates to depilation by photocoagulation means and methods and in particular to the use of light energy to destroy hair.
BACKGROUND OF THE INVENTION It is desirable to introduce means and methods for removing unwanted body hair painlessly. In the conventional state of the art, processes where electrolysis by either galvanic current electrochemical or high frequency diathermy techniques are employed, thermal coagulation of the tissues at the hair root takes place. These techniques, however, are not painless and are difficult to administer and gauge. Thus, expert operators must be available to determine dosage and conditions for use of these methods.
Light has been used, historically in the treatment of a number of medical problems, but until the advent of the laser, its use as a coagulator of local tissues was not widespread.
Zeiss of Germany has manufactured a Xenon arc lamp device to coagulate retinal tissue in the case of detached retina, but this was a very large, cumbersome, inefficient and costly device.
The ruby laser provided to be acceptable for the purpose of welding detached retinas, and other uses for laser coagulation have been suggested, including the epilation of hair by destruction of vascular papilla which feeds the germinal hair cells at the base of the follicle.
bed. In order to have effective absorption, enormous energy must be delivered because of the mismatch, and this degree of energy was sufficient to destroy the glass fiber probes.
Literature sources provide some indices to be used in determining threshold levels of coagulation of human and animal tissues using light energy. This data is available, primarily for the vascular and pigmented connective tissues of the retina. As Table 1 below indicates (1) F A LEsperance Jr. and G.R. Kelly, The Threshold of the Retina to Damage by Argon Laser Radiation" Arch. Ophthal. Vol. 81, April 1969, 588 reported the determination of threshold levels of photocoagulation in the rabbit and monkey retina, using argon gas lasers whose output energy was contained in several lines between 4,579 angstroms and 5,145 angstroms in the blue-green portion of the spectrum. For comparitive purposes it should be noted that a Xenon flash lamp used in this invention was a black body radiator with peak energy at about 4,000 angstroms and much of its energy below 5500 angstroms. Thus, the comparison between these sources, in regard to biological effects, is quite reasonable.
The general levels for threshold effect, as determined by visual si n of tissue coagulation, proved to be on the order of 2 to 6 joules per square centimeter. LEsperance reported that in an earlier study done with Xenon light by WJ. Gerraets, W.T. Ham, R.C. Wil-- liams Jr., H.A. Mueller, J. Burkhart, D. Guerry, and J .J Vos, Laser vs light coagular; A Funduscopic and Histological Study of Chonoretinal Injury as a function of exposure time. Fed. Proceedings Vol. 24, No. 1, Part III, Jan-Feb. 1965, the threshold level was determined to be 4 joules per square centimeter as compared with his values of 2 to 6 joules per square centimeter for green laser light. The pulse lengths of the Gerraets'study with Xenon arc lamps were varied from microseconds to 30 milliseconds. A summary of the data of both studies is given in Table 1 below along with comparative data on the measured performance of a model built in accordance with the present invention?" In a report following a careful measurement program of blood and tissue absorption, the present inventors determined that maximum efficiency for coupling to hemoglobin with minimum absorption in surrounding tissue could be accomplished by utilizing blue-green light of from 530-560 nanometer wave length. They, therefore suggested a doubled neodymium laser with spectrum output at 5 30 nm.
It is accordingly an object of the present invention to provide painless, simple to administer means and method of photocoagulation of tissue useful in depi1ation, and the like.
The invention, together with other objectives, features and advantages is described hereinafter with reference to the embodiments set forth in the accompanying drawings.
DRAWINGS FIG. 1 is a schematic view, partially in block diagram of a Xenon arc photoepilator, showing in section view the probe as inserted into a follicle;
FIG. 2 is a view in perspective, partly diagrammatic of a linear flash lamp device as used in accordance with the invention, and
FIG. 3 is an enlarged fragmentary view in elevation and in section of the needle inserted into the hair follicle.
Therefore, in accordance with one embodiment (see FIG. 1), photocoagulation is accomplished by transmitting pulsed light energy from an arc source to terminate in the region of a hair root follicle with just enough energy in a very short pulse to destroy the life processes in the hair. In accordance with some other r 3 aspects of the invention, specific absorption of green light energy by hemoglobin may be effected to photocoagulate the blood vessel structure nourishing the hair root without significant absorption in other non-pigmented tissues at or near the hair follicle.
High energy light bursts may be obtained from gas discharge lamps 5 such as Mercury, Xenon, Argon, etc. Flash durations may be controlled by conventional pulsed power supplies 6, initiated at any desired instant by means of a switch 7, for example. Various spectral qualities can be obtained from available gas discharge lamps by employing different gases, pressures, optical filters, etc.
Typically, lamp 5 is a high peak power pulsed Xenon arc source producing peak powers in excess of 30 kilowatts when an operator closes switch 7, which might be a foot pedal trigger. The lamp produces a flash of intense visible radiation in less than a few milliseconds. Because this duration is less than the Chronaxie" for pain fibers, there is no sensation created by the energy in the body.
The flash pulse may be obtained from a bank of storage capacitors which delivers up to 660 joules in less than a three millisecond period. These capacitors are recharged within one second, and ready to deliver the next pulse.
A spherical mirror or lens 8 of high optical speed (f/0.5) collimates the light in rays 9. The collimated light is focused by a lens system 10 as shown by rays 11 to be concentrated at the end of a flexible conduit 12 which, for example, is a single glass fiber 100 microns in diameter. A flexible steel sheath 14 or other surgical tubing may encompass the light conduit 12 to confine light and protect the fiber 12. Preferably, the steel sheath 14 is covered with polyvinyl chloride.
The ends of the fiber are carefully ground and polished to permit the maximum light energy to escape. Overall the probes may be about 48 to 60 inches long with transmission losses that should approximate no greater than about 60 percent.
At the terminal or distal tip end 15 of fiber 12, where the light energy escapes, is a stainless steel hollow needle or stainless steel tubing 17 of typically 125 to 200 microns in diameter and about 2 mm. to 4 mm. in length held in a holder 16 similar to a hypodermic syringe. This structure serves to introduce the fiber near the root 18 of hair 19 under the skin surface 20. The needle 17 serves the function of preventing escape of light energy at any other point than the terminal end 15 of fiber 12 to thereby concentrate all the energy at a known position in the vicinity of hair follicle 21. to thereby depilate the hair without damage to other surrounding tissue. The drawing shows various features out of size proportion in order to show the details and the particular mode of depilation provided by this invention.
In order to further selectively protect the adjoining tissue about the hair root 18, the light energy from are lamp 5 may be further selected or confined to a particular waveband such as that provided by a double neodymium selective output laser, by introduction of selective filter 22. Thus, for example, light energy entering fiber 12 may be confined to green light of approximately 530 millimicron wavelength. This wavelength provides for specific absorption of the bulk of the photo energy by hemoglobin, resulting in photocoagulation of the blood vessel structure 23 in the vicinity of follicle 21 that nourishes the hair root with minimal absorption in other non-pigmented tissues at or near the hair follicle. Ultraviolet energy at about 280 millimicrons wavelength could also be used for maximum absorption in the protein materials at the hair root 18.
It has been found that the amount of photo energy to be supplied by the arc lamp source for effective use in hair depilation without sensing pain or incurring significant damage to surrounding tissue is of the order of 20 to I00 joules per square centimeter at the proximal end ofa micron diameter fiber which would give about 5 to 30 joules per square centimeter at the distal end of the fiber. Several successive flashes one second apart may be administered. This energy is a function of the light intensity and pulse duration, both of which may be varied to provide the optimum energy output at the follicle, but the time duration is preferably less than 3 milliseconds.
In laboratory experiments with humans, in photoepilation, it has been shown that 68 percent of the hairs release well under such conditions, with hair roots often showing a matchstick" effect of burnt or shrivelled appearance. Biopsies showed no more than slight irritation in any case after such epilation and there were no reports of pain at the flash or afterwards. The surrounding tissue was not damaged.
Accordingly, the photocoagulation means and method afforded by this embodiment results in a simple practical improvement over prior art depilation techniques.
Another embodiment comprises a linear flash lamp having an arc length greater than 10 millimeters, preferably in the order of 40 millimeters. it provides for direct takeoff by a fiber optic cable located close to the exterior of the lamp, the takeoff being from approximately the center of the arc. Energy control may be ob tained by regulating the distance of the cable end from the arc.
This embodiment does not require an extensive optical system as described in the first embodiment and thus it has been found that this type of lamp has a relatively long lifetime and gives a higher energy output at a not much greater energy input.
This embodiment (see FIG. 2) comprises a linear flash lamp having two electrodes 111 and 112 located a substantial distance apart in an envelope 113. The electrodes 111 and 112 should be at least 10 millimeters apart; for example, one such lamp on the market has an arc length of 39 millimeters. The distance should be contrasted with the short arcs heretofore used, where the arc length was in the nature of 1 mil limeter. The envelope 113 is also preferably very slender, typically cylindrical, and in the nature of a capillary tube. A typical diameter for such a lamp 110 is 5 millimeters, as contrasted with the 25 millimeter diameter of typical short are lamps a feature which made it impossible to get very close to the are or to get very good control of the location.
A pulsed power supply 114 is connected to the linear flash lamp, any suitable pulsing means being used. The lamp 110 may be held in place by suitable supports 115 secured to a base 116.
In conjunction with the linear flash lamp 110, this embodiment employs an optical fiber type of cable 12th, which may comprise a single glass fiber 121 typitheir lengths approximating no more than 50 per cent.
Near the outlet end of needle 125, a handle 126 is provided for use of the operator. The input end 124 of the fiber optic cable l2l lies closely adjacent the flash lamp 110.
A constant energy input of about 300 joules is a typical amount with the linear flash lamp 310, and this contrasts with the somewhat lower 60 to 200 joules, a variable amount, used in a short-arc lamp of this type.
Optics such as lenses are not required in this device, and it is noted that the energy output is greater than 0.6 millijoules as compared with an output less than 0.1 millijoule in a short are having an input of up to 200 joules. Thus, a much greater efiiciency and energy output are obtained.
in use for photoepilation, the needle 125 is inserted individually into each hair follicle, as shown in FIG. 3, operating on the principle of selective damage to hair papilla and blood supply, so that it does not affect the surrounding cells. The device is lightweight and portable, and no realignment is required between uses. It may, for example, have a 5-foot cable and the probe may be 5 or 7 mils in diameter. The harmless (to all but the hair papilla and their blood supply) high intensity light enables longer treatment sessions, and treatment of special problem areas. The selective absorption prevents scarring, and there are no hot probes to cause discomfort, so that inflammation and swelling are minimized.
It should be noted that an advantage of the I photoepilation technique over the thermolysis technique is the distance the needle must penetrate into the skin into the hair follicle in order to destroy it. Using the photoepilation technique the needle need only penetrate the skin into the follicle a small distance, approximately one-sixteenth inch, whereas the use of the thermolysis technique requires the placement of the needle down near the root of the follicle in order to properly treat the hair. Therefore, the light transmitting means in photoepilation need only be inserted a small distance into the follicle to destroy the hair. Thus there is less chance of accidentally damaging the surrounding tissue along with a further reduction in pain utilizing the photoepilation technique.
in a modified form of this embodiment, the apparance is exactly the same except at the output end, where in place of a needle there is merely a blunt end. In this instance, the fiber optics cable is somewhat larger, for example, about one-eighth inch in diameter and contains several thousand individual smalldiameter fibers. Otherwise the structure is unchanged. As a result, over 20 millijoules of energy can be trum and is capable of coagulating retinal blood vessels.
10 What is claimed is;
1. The method of epilation, comprising in combination the steps of a. Producing a pulse of high energy light by electronilight radiation,
b. Positioning a flexible thin single fiber conduit formed from fiberoptic material capable of transmitting said light energy from the gaseous media so that the input end of said conduit collects intense light from said high energy light and the output end of said conduit is positioned in a hair follicle, and
c. Transmitting said pulse of light energy in said conduit with enough energy passed through said conduit to said hair follicle to cause photocoagulation of body tissue in the vicinity of said region at an intensity killing the hair.
2. The method defined in claim 1, including the additional step of limiting the frequency of the light energy to a predetermined bandwidth.
3. The method defined in claim 2, including the additional step of producing light of a wavelength in the green region of the light spectrum that is specifically absorbed by hemoglobin, thereby selectively photocoagulating the blood vessel structure about the region with the light energy becoming significantly absorbed in other nonpigmented tissues near the region. 7
v 4. The method defined in claim 2, including the additional step of limiting the light energy supplied to the follicle to less than 3 millijoules.
' 5. The method defined in claim 1 including the step of limiting the light pulse to less than 3 milliseconds in duration.
6. The method as defined in claim 1 including the step of successively flashing said light energy a plurality of times at approximately 1 second intervals.
7. The method defined in claim 1, including locating the output end of said conduit only partly within said hair follicle.
8. Depilation apparatus for depilationby photocoagulation in a limited region about a hair root comprising in combination,
a. A high energy gaseous medium light source including electrical means for producing therein short intense pulses of light,
b. A single fiber conduit formed from fiberoptic material positioned to transmit light energy from said source to said region with a polished end for inserting into the follicle for releasing the transmitted light energy in said body tissue, and
c. Means for locating said polished output end of said conduit in the follicle.
9. Apparatus as claimed in claim 8, wherein said locating means comprises a needle having a cavity therein for receiving a portion, of said conduit at the terminating end. .5"
cally triggering a gaseous media to produce visible 10. Apparatus as defined in claim 8 wherein said light energy producing means further comprises a spherical lens of high optical speed which eollimates said light in rays.
11. Apparatus as defined in claim 10, including a lens system for focusing said collimated light to be concentrated at the end of said flexible conduit.
12. Apparatus as defined in claim 8, further comprising means for producing light energy from said pulse to provide light in a specific range of the spectrum.
l3. Apparatus as defined in claim 12, wherein said light as provided in the green range of the spectrum.
14. Apparatus as claimed in claim 12, wherein said light is provided having a wave length of approximately 530 nanometers.
15. Apparatus as claimed in claim 8, in which means provides light energy at the end of said conduit to reach said region with approximately one-half to 3 millijoules.
l6. Apparatus as claimed in claim 8 limited to produce light flashes ofless than 3 milliseconds in duratron.
17. Apparatus as claimed in claim 16 adapted to produce a series of successive flashes at approximately 1 second intervals.
18. Photoepilation, comprising producing pulses primarily of blue-green high-energy light in a gaseous medium across an are longer than the millimeters,
transmitting said light through a single fiber optic filament of about 5 to 7 mills thickness directly from an input end adjacent said are to a needle end,
inserting said needle end into a hair follicle, and
transmitting into said follicle the pulses for a time sufficient to coagulate the tissue therein responsible for hair growth.
19. Photoepilation according to claim 18 wherein the energy input is approximately 300 joules and the output is greater than 0.6 millijoules.
20. Photoepilation according to claim 18, wherein in said inserting step said needle is inserted only partly into said hair follicle.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3327712 *||Sep 15, 1961||Jun 27, 1967||Ira H Kaufman||Photocoagulation type fiber optical surgical device|
|US3471215 *||Jul 16, 1965||Oct 7, 1969||American Optical Corp||Fiber laser device provided with long flexible energy-directing probe-like structure|
|US3538919 *||Apr 7, 1967||Nov 10, 1970||Gregory System Inc||Depilation by means of laser energy|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3834391 *||Jan 19, 1973||Sep 10, 1974||Block Carol Ltd||Method and apparatus for photoepilation|
|US4122853 *||Mar 14, 1977||Oct 31, 1978||Spectra-Med||Infrared laser photocautery device|
|US4185633 *||Sep 7, 1976||Jan 29, 1980||Malyshev Boris N||Method of surgical treatment using laser emission and apparatus for realizing same|
|US4299229 *||Dec 5, 1979||Nov 10, 1981||Cavitron Corporation||Method of observing the aim or effect of a laser beam on a target|
|US4311138 *||Mar 10, 1980||Jan 19, 1982||Sugarman Edward D||Illuminated hypodermic needle|
|US4388924 *||May 21, 1981||Jun 21, 1983||Weissman Howard R||Method for laser depilation|
|US4537193 *||Oct 28, 1982||Aug 27, 1985||Hgm, Inc.||Laser endocoagulator apparatus|
|US4567882 *||Dec 10, 1984||Feb 4, 1986||Vanderbilt University||Method for locating the illuminated tip of an endotracheal tube|
|US4608978 *||Sep 26, 1983||Sep 2, 1986||Carol Block Limited||Method and apparatus for photoepiltion|
|US4617926 *||Jan 30, 1984||Oct 21, 1986||Sutton A Gunilla||Depilation device and method|
|US4658817 *||Apr 1, 1985||Apr 21, 1987||Children's Hospital Medical Center||Method and apparatus for transmyocardial revascularization using a laser|
|US4784132 *||Sep 5, 1985||Nov 15, 1988||Fox Kenneth R||Method of and apparatus for laser treatment of body lumens|
|US4800876 *||Mar 25, 1983||Jan 31, 1989||Fox Kenneth R||Method of and apparatus for laser treatment of body lumens|
|US4819669 *||Apr 1, 1986||Apr 11, 1989||Politzer Eugene J||Method and apparatus for shaving the beard|
|US4848336 *||Jul 29, 1988||Jul 18, 1989||Fox Kenneth R||Apparatus for laser treatment of body lumens|
|US4873446 *||Jul 6, 1988||Oct 10, 1989||Albert Kreitmair||Device for irradiating denture parts|
|US5041108 *||Jun 9, 1989||Aug 20, 1991||Pillco Limited Partnership||Method for laser treatment of body lumens|
|US5182857 *||Oct 29, 1990||Feb 2, 1993||U.S. Philips Corp.||Shaving apparatus|
|US5207673 *||Dec 6, 1991||May 4, 1993||Premier Laser Systems, Inc.||Fiber optic apparatus for use with medical lasers|
|US5226907 *||Oct 29, 1991||Jul 13, 1993||Tankovich Nikolai I||Hair removal device and method|
|US5280788 *||Feb 26, 1991||Jan 25, 1994||Massachusetts Institute Of Technology||Devices and methods for optical diagnosis of tissue|
|US5300066 *||Jun 23, 1992||Apr 5, 1994||Coherent, Inc.||Contact laser delivery system|
|US5320618 *||Apr 9, 1991||Jun 14, 1994||Morgan Gustafsson||Device for treatment of undesired skin disfigurements|
|US5344418 *||Dec 12, 1991||Sep 6, 1994||Shahriar Ghaffari||Optical system for treatment of vascular lesions|
|US5344434 *||Dec 21, 1992||Sep 6, 1994||Technion Research & Development Foundation, Ltd.||Apparatus for the photodynamic therapy treatment|
|US5595568 *||Feb 1, 1995||Jan 21, 1997||The General Hospital Corporation||Permanent hair removal using optical pulses|
|US5606798 *||Mar 10, 1992||Mar 4, 1997||Kelman; Elliot||Hair cutting apparatus|
|US5630811 *||Mar 25, 1996||May 20, 1997||Miller; Iain D.||Method and apparatus for hair removal|
|US5632741 *||Jan 20, 1995||May 27, 1997||Lucid Technologies, Inc.||Epilation system|
|US5647866 *||May 14, 1996||Jul 15, 1997||Zaias; Nardo||Method of hair depilation|
|US5653706 *||Feb 27, 1995||Aug 5, 1997||Lucid Technologies Inc.||Dermatological laser treatment system with electronic visualization of the area being treated|
|US5658323 *||Oct 23, 1995||Aug 19, 1997||Miller; Iain D.||Method and apparatus for dermatology treatment|
|US5683380 *||Mar 29, 1995||Nov 4, 1997||Esc Medical Systems Ltd.||Method and apparatus for depilation using pulsed electromagnetic radiation|
|US5713845 *||Jun 12, 1995||Feb 3, 1998||Thermolase Corporation||Laser assisted drug delivery|
|US5735844 *||Jan 30, 1996||Apr 7, 1998||The General Hospital Corporation||Hair removal using optical pulses|
|US5752948 *||Jun 19, 1995||May 19, 1998||Thermolase Corporation||Hair removal method|
|US5752949 *||May 13, 1996||May 19, 1998||Thermolase Corporation||Hair removal method|
|US5755751 *||Jun 7, 1995||May 26, 1998||Esc Medical Systems Ltd.||Method and apparatus for therapeutic electromagnetic treatment|
|US5769840 *||May 22, 1995||Jun 23, 1998||Schirmer; Kurt E.||Microsurgery using alternating disruptive and thermal laser beam pulses|
|US5769844 *||Jun 7, 1995||Jun 23, 1998||Ghaffari; Shahriar||Conventional light-pumped high power system for medical applications|
|US5785704 *||Jul 29, 1996||Jul 28, 1998||Mrc Systems Gmbh||Method for performing stereotactic laser surgery|
|US5817089 *||Jun 12, 1995||Oct 6, 1998||Thermolase Corporation||Skin treatment process using laser|
|US5836938 *||Dec 18, 1996||Nov 17, 1998||Slatkine; Michael||Hair removal with a laser system and waveguide for radial transmission of laser energy|
|US5843072 *||Nov 7, 1996||Dec 1, 1998||Cynosure, Inc.||Method for treatment of unwanted veins and device therefor|
|US5853407 *||Apr 18, 1997||Dec 29, 1998||Luxar Corporation||Method and apparatus for hair removal|
|US5860967 *||Jul 21, 1993||Jan 19, 1999||Lucid, Inc.||Dermatological laser treatment system with electronic visualization of the area being treated|
|US5871479 *||Nov 7, 1996||Feb 16, 1999||Cynosure, Inc.||Alexandrite laser system for hair removal and method therefor|
|US5871480 *||Jul 25, 1997||Feb 16, 1999||Thermolase Corporation||Hair removal using photosensitizer and laser|
|US5876397 *||Sep 29, 1992||Mar 2, 1999||Boston Scientific Corporation||Reduction of an arteriosclerotic lesion by selective absorption of electromagnetic energy in a component thereof|
|US5879346 *||Dec 17, 1996||Mar 9, 1999||Esc Medical Systems, Ltd.||Hair removal by selective photothermolysis with an alexandrite laser|
|US5879376 *||May 20, 1996||Mar 9, 1999||Luxar Corporation||Method and apparatus for dermatology treatment|
|US5885273 *||Feb 9, 1996||Mar 23, 1999||Esc Medical Systems, Ltd.||Method for depilation using pulsed electromagnetic radiation|
|US5925035 *||Aug 1, 1996||Jul 20, 1999||Thermolase Corporation||Hair removal method|
|US5993440 *||Feb 20, 1998||Nov 30, 1999||Ghassemi; Faramarz Frank||Non-invasive laser cutting device and method|
|US6027495 *||Mar 20, 1997||Feb 22, 2000||Esc Medical Systems Ltd.||Method and apparatus for dermatology treatment|
|US6036684 *||Oct 6, 1998||Mar 14, 2000||Thermolase Corporation||Skin treatment process using laser|
|US6045548 *||Sep 22, 1998||Apr 4, 2000||Cynosure, Inc.||Alexandrite laser system for hair removal and method therefor|
|US6050990 *||Dec 4, 1997||Apr 18, 2000||Thermolase Corporation||Methods and devices for inhibiting hair growth and related skin treatments|
|US6063074 *||Dec 31, 1996||May 16, 2000||Thermolase Corporation||Hair removal using a contaminant matched to a laser|
|US6104959 *||Jul 31, 1997||Aug 15, 2000||Microwave Medical Corp.||Method and apparatus for treating subcutaneous histological features|
|US6152917 *||Dec 18, 1997||Nov 28, 2000||Thermolase Corporation||Hair removal device|
|US6162211 *||Dec 4, 1997||Dec 19, 2000||Thermolase Corporation||Skin enhancement using laser light|
|US6168590||Aug 11, 1998||Jan 2, 2001||Y-Beam Technologies, Inc.||Method for permanent hair removal|
|US6228075||Mar 15, 1999||May 8, 2001||Cynosure, Inc.||Alexandrite laser system for hair removal|
|US6267771||Feb 27, 1996||Jul 31, 2001||Thermotrex Corporation||Hair removal device and method|
|US6273883||Apr 8, 1997||Aug 14, 2001||Cynosure, Inc.||Alexandrite laser system for treatment of dermatological specimens|
|US6273884||May 13, 1998||Aug 14, 2001||Palomar Medical Technologies, Inc.||Method and apparatus for dermatology treatment|
|US6383176||Mar 15, 1999||May 7, 2002||Altus Medical, Inc.||Hair removal device and method|
|US6461348||Aug 27, 1999||Oct 8, 2002||Howard S. Bertan||Photo-thermal epilation apparatus with advanced energy storage arrangement|
|US6485484||Sep 10, 1999||Nov 26, 2002||Altus Medical, Inc.||Hair removal device|
|US6508813||Mar 12, 1999||Jan 21, 2003||Palomar Medical Technologies, Inc.||System for electromagnetic radiation dermatology and head for use therewith|
|US6511475||Aug 9, 2000||Jan 28, 2003||The General Hospital Corporation||Heads for dermatology treatment|
|US6514243||Feb 17, 2000||Feb 4, 2003||Lumenis Ltd.||Method and apparatus for electromagnetic treatment of the skin, including hair depilation|
|US6517532||Dec 28, 1999||Feb 11, 2003||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US6558411 *||May 11, 1998||May 6, 2003||Photocure Asa||Device for illuminating a defined area|
|US6569155||Mar 13, 2000||May 27, 2003||Altus Medical, Inc.||Radiation delivery module and dermal tissue treatment method|
|US6575964||Feb 4, 2000||Jun 10, 2003||Sciton, Inc.||Selective aperture for laser delivery system for providing incision, tissue ablation and coagulation|
|US6605080||Mar 26, 1999||Aug 12, 2003||The General Hospital Corporation||Method and apparatus for the selective targeting of lipid-rich tissues|
|US6610052||Aug 9, 2001||Aug 26, 2003||Cynosure, Inc.||Laser system and method for treatment of biologic targets|
|US6613042 *||Jun 30, 2000||Sep 2, 2003||Nikolai Tankovich||Rainbow laser|
|US6632218||Oct 21, 1999||Oct 14, 2003||Cynosure, Inc.||Alexandrite laser system for hair removal and method therefor|
|US6653618||Apr 30, 2001||Nov 25, 2003||Palomar Medical Technologies, Inc.||Contact detecting method and apparatus for an optical radiation handpiece|
|US6663620||Jan 18, 2002||Dec 16, 2003||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US6719753||Jun 22, 2002||Apr 13, 2004||Howard Stephen Bertan||Means and method for energizing a flash lamp|
|US6723090||Jul 2, 2002||Apr 20, 2004||Palomar Medical Technologies, Inc.||Fiber laser device for medical/cosmetic procedures|
|US6743221||Mar 12, 2002||Jun 1, 2004||James L. Hobart||Laser system and method for treatment of biological tissues|
|US6770069||Jun 21, 2002||Aug 3, 2004||Sciton, Inc.||Laser applicator|
|US6878144||Sep 17, 2002||Apr 12, 2005||Palomar Medical Technologies, Inc.||System for electromagnetic radiation dermatology and head for use therewith|
|US6916315||Oct 7, 2002||Jul 12, 2005||Kenneth Lawrence Short||Methods of operating a photo-thermal epilation apparatus|
|US6974451||Dec 16, 2003||Dec 13, 2005||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US6976985||Apr 17, 2003||Dec 20, 2005||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US6991644||Dec 5, 2003||Jan 31, 2006||Cutera, Inc.||Method and system for controlled spatially-selective epidermal pigmentation phototherapy with UVA LEDs|
|US6997923||Dec 27, 2001||Feb 14, 2006||Palomar Medical Technologies, Inc.||Method and apparatus for EMR treatment|
|US7029469||Feb 4, 2003||Apr 18, 2006||Palomar Medical Technologies, Inc.||Method and apparatus for laser removal of hair|
|US7041094||Oct 16, 2003||May 9, 2006||Cutera, Inc.||Tissue treatment device and method|
|US7044959||Mar 12, 2003||May 16, 2006||Palomar Medical Technologies, Inc.||Method and apparatus for hair growth management|
|US7060061||Aug 12, 2003||Jun 13, 2006||Palomar Medical Technologies, Inc.||Method and apparatus for the selective targeting of lipid-rich tissues|
|US7077840||Oct 21, 2002||Jul 18, 2006||Palomar Medical Technologies, Inc.||Heads for dermatology treatment|
|US7108689||Sep 19, 2002||Sep 19, 2006||Lumenis Ltd||Method and apparatus for electromagnetic treatment of the skin, including hair depilation|
|US7118562||Jul 31, 2003||Oct 10, 2006||Cynosure, Inc.||Laser system and method for treatment of biologic targets|
|US7118563||Feb 19, 2004||Oct 10, 2006||Spectragenics, Inc.||Self-contained, diode-laser-based dermatologic treatment apparatus|
|US7135033||Oct 23, 2003||Nov 14, 2006||Palomar Medical Technologies, Inc.||Phototreatment device for use with coolants and topical substances|
|US7147654 *||Jan 24, 2003||Dec 12, 2006||Laserscope||Treatment Site Cooling System of Skin Disorders|
|US7204832||May 23, 2002||Apr 17, 2007||Pálomar Medical Technologies, Inc.||Cooling system for a photo cosmetic device|
|US7220254||Dec 31, 2004||May 22, 2007||Palomar Medical Technologies, Inc.||Dermatological treatment with visualization|
|US7220256||Sep 23, 2003||May 22, 2007||Hobart James L||Laser system and method for treatment of biological tissues|
|US7250045||Feb 19, 2004||Jul 31, 2007||Spectragenics, Inc.||Self-contained, eye-safe hair-regrowth-inhibition apparatus and method|
|US7274155||Mar 28, 2005||Sep 25, 2007||Palomar Medical Technologies, Inc.||Flash lamp drive circuit|
|US7276058||Jun 19, 2003||Oct 2, 2007||Palomar Medical Technologies, Inc.||Method and apparatus for treatment of cutaneous and subcutaneous conditions|
|US7291140||Mar 5, 2004||Nov 6, 2007||Cutera, Inc.||System and method for low average power dermatologic light treatment device|
|US7309335||Dec 31, 2004||Dec 18, 2007||Palomar Medical Technologies, Inc.||Dermatological treatment with visualization|
|US7326199||Feb 27, 2004||Feb 5, 2008||Cutera, Inc.||System and method for flexible architecture for dermatologic treatments utilizing multiple light sources|
|US7351252||Jun 19, 2003||Apr 1, 2008||Palomar Medical Technologies, Inc.||Method and apparatus for photothermal treatment of tissue at depth|
|US7354433 *||Feb 26, 2004||Apr 8, 2008||Advanced Light Technologies, Llc||Disinfection, destruction of neoplastic growth, and sterilization by differential absorption of electromagnetic energy|
|US7413567||Feb 25, 2004||Aug 19, 2008||Spectragenics, Inc.||Optical sensor and method for identifying the presence of skin|
|US7431719||Mar 30, 2005||Oct 7, 2008||Palomar Medical Technologies, Inc.||System for electromagnetic radiation dermatology and head for use therewith|
|US7452356||Feb 19, 2004||Nov 18, 2008||Tria Beauty, Inc.||Eye-safe dermatologic treatment apparatus|
|US7452358||Mar 25, 2003||Nov 18, 2008||Thermage, Inc.||RF electrode assembly for handpiece|
|US7465307||Nov 2, 2005||Dec 16, 2008||Cutera, Inc.||Tissue treatment system|
|US7473251||Mar 31, 2003||Jan 6, 2009||Thermage, Inc.||Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient|
|US7481809||Jun 20, 2005||Jan 27, 2009||Thermage, Inc.||Handpiece with RF electrode and non-volatile memory|
|US7524328||Mar 14, 2003||Apr 28, 2009||Cutera, Inc.||Radiation delivery module and dermal tissue treatment method|
|US7531967||Sep 24, 2007||May 12, 2009||Palomar Medical Technologies, Inc.||Flashlamp drive circuit|
|US7540869||Dec 27, 2002||Jun 2, 2009||Palomar Medical Technologies, Inc.||Method and apparatus for improved vascular related treatment|
|US7618414||Feb 3, 2006||Nov 17, 2009||Cutera, Inc.||Tissue treatment system|
|US7722600||Nov 23, 2004||May 25, 2010||Cutera, Inc.||System and method for heating skin using light to provide tissue treatment|
|US7758621||May 19, 2006||Jul 20, 2010||Palomar Medical Technologies, Inc.||Method and apparatus for therapeutic EMR treatment on the skin|
|US7763016||Dec 12, 2005||Jul 27, 2010||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US7780652||Dec 10, 2007||Aug 24, 2010||Cutera, Inc.||System and method for flexible architecture for dermatologic treatments utilizing multiple light sources|
|US7837675||May 31, 2005||Nov 23, 2010||Shaser, Inc.||Method and device for skin treatment with replaceable photosensitive window|
|US7891362||Dec 22, 2006||Feb 22, 2011||Candela Corporation||Methods for treating pigmentary and vascular abnormalities in a dermal region|
|US7935107||May 19, 2010||May 3, 2011||Palomar Medical Technologies, Inc.||Heads for dermatology treatment|
|US7942915||Nov 13, 2006||May 17, 2011||Palomar Medical Technologies, Inc.||Phototreatment device for use with coolants|
|US7942916||Dec 1, 2006||May 17, 2011||Palomar Medical Technologies, Inc.||Phototreatment device for use with coolants and topical substances|
|US7981111||Feb 25, 2004||Jul 19, 2011||Tria Beauty, Inc.||Method and apparatus for the treatment of benign pigmented lesions|
|US8002768||Jul 21, 2010||Aug 23, 2011||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US8073550||Aug 14, 2000||Dec 6, 2011||Miramar Labs, Inc.||Method and apparatus for treating subcutaneous histological features|
|US8109924||Mar 24, 2011||Feb 7, 2012||Palomar Medical Technologies, Inc.||Heads for dermatology treatment|
|US8182473||Nov 22, 2006||May 22, 2012||Palomar Medical Technologies||Cooling system for a photocosmetic device|
|US8226696||Jun 16, 1998||Jul 24, 2012||Ellipse A/S||Light pulse generating apparatus and cosmetic and therapeutic phototreatment|
|US8246611||Jun 14, 2007||Aug 21, 2012||Candela Corporation||Treatment of skin by spatial modulation of thermal heating|
|US8246613||Oct 4, 2010||Aug 21, 2012||Shaser, Inc.||Method and apparatus of treating tissue|
|US8268332||Apr 1, 2005||Sep 18, 2012||The General Hospital Corporation||Method for dermatological treatment using chromophores|
|US8277495||Sep 16, 2005||Oct 2, 2012||Candela Corporation||Method and apparatus for treating a diseased nail|
|US8328794||Sep 22, 2008||Dec 11, 2012||Palomar Medical Technologies, Inc.||System for electromagnetic radiation dermatology and head for use therewith|
|US8328796||Jul 11, 2011||Dec 11, 2012||Palomar Medical Technologies, Inc.||Light energy delivery head|
|US8346347||Sep 15, 2006||Jan 1, 2013||Palomar Medical Technologies, Inc.||Skin optical characterization device|
|US8367959||Oct 24, 2011||Feb 5, 2013||Miramar Labs, Inc.||Method and apparatus for treating subcutaneous histological features|
|US8401668||Sep 27, 2011||Mar 19, 2013||Miramar Labs, Inc.||Systems and methods for creating an effect using microwave energy to specified tissue|
|US8406894||Sep 27, 2011||Mar 26, 2013||Miramar Labs, Inc.||Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy|
|US8460280||Jun 11, 2013||Cutera, Inc.||Localized flashlamp skin treatments|
|US8469951||Nov 15, 2012||Jun 25, 2013||Miramar Labs, Inc.||Applicator and tissue interface module for dermatological device|
|US8535302||Nov 15, 2012||Sep 17, 2013||Miramar Labs, Inc.||Applicator and tissue interface module for dermatological device|
|US8551104||Oct 10, 2006||Oct 8, 2013||Tria Beauty, Inc.||Self-contained, diode-laser-based dermatologic treatment apparatus|
|US8685017||Jun 6, 2007||Apr 1, 2014||Thermage, Inc.||Method and kit for treatment of tissue|
|US8688228||Dec 12, 2008||Apr 1, 2014||Miramar Labs, Inc.||Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy|
|US8709003||Aug 8, 2008||Apr 29, 2014||Tria Beauty, Inc.||Capacitive sensing method and device for detecting skin|
|US8723121 *||Nov 27, 2008||May 13, 2014||The Flewelling Ford Family Trust||Identification system and method using highly collimated source of electromagnetic radiation|
|US8777935||Aug 18, 2008||Jul 15, 2014||Tria Beauty, Inc.||Optical sensor and method for identifying the presence of skin|
|US8790381||Feb 20, 2008||Jul 29, 2014||Photometics, Inc.||Disinfection, destruction of neoplastic growth, and sterilization by differential absorption of electromagnetic energy|
|US8825176||Feb 20, 2013||Sep 2, 2014||Miramar Labs, Inc.||Apparatus for the noninvasive treatment of tissue using microwave energy|
|US8853600||Nov 9, 2012||Oct 7, 2014||Miramar Labs, Inc.||Method and apparatus for treating subcutaneous histological features|
|US8870856||Feb 27, 2004||Oct 28, 2014||Cutera, Inc.||Method for heating skin using light to provide tissue treatment|
|US8915906||Aug 8, 2005||Dec 23, 2014||Cutera, Inc.||Method for treatment of post-partum abdominal skin redundancy or laxity|
|US8915948||Feb 15, 2008||Dec 23, 2014||Palomar Medical Technologies, Llc||Method and apparatus for photothermal treatment of tissue at depth|
|US9028469||Sep 28, 2006||May 12, 2015||Candela Corporation||Method of treating cellulite|
|US9028477||Sep 3, 2013||May 12, 2015||Miramar Labs, Inc.||Applicator and tissue interface module for dermatological device|
|US9028536||Aug 3, 2009||May 12, 2015||Cynosure, Inc.||Picosecond laser apparatus and methods for its operation and use|
|US9149331||Apr 18, 2008||Oct 6, 2015||Miramar Labs, Inc.||Methods and apparatus for reducing sweat production|
|US20020091377 *||Jan 25, 2001||Jul 11, 2002||Anderson R. Rox||Method and apparatus for medical treatment utilizing long duration electromagnetic radiation|
|US20020161357 *||Dec 27, 2001||Oct 31, 2002||Anderson R. Rox||Method and apparatus for EMR treatment|
|US20030065314 *||Sep 17, 2002||Apr 3, 2003||Palomar Medical Technologies, Inc.||System for electromagnetic radiation dermatology and head for use therewith|
|US20030069567 *||Sep 19, 2002||Apr 10, 2003||Shimon Eckhouse||Method and apparatus for electromagnetic treatment of the skin, including hair depilation|
|US20030144713 *||Jan 21, 2003||Jul 31, 2003||Cynosure, Inc.||Ultra-long flashlamp-excited pulse dye laser for therapy and method therefor|
|US20030195494 *||Apr 17, 2003||Oct 16, 2003||Altshuler Gregory B.||Light energy delivery head|
|US20030199859 *||May 21, 2003||Oct 23, 2003||Altshuler Gregory B.||Method and apparatus for the selective targeting of lipid-rich tissues|
|US20040015156 *||Feb 4, 2003||Jan 22, 2004||Vasily David B.||Method and apparatus for laser removal of hair|
|US20040034319 *||Mar 12, 2003||Feb 19, 2004||Palomar Medical Technologies, Inc.||Method and apparatus for hair growth management|
|US20040034341 *||Aug 12, 2003||Feb 19, 2004||Palomar Medical Technologies, Inc.||Method and apparatus for the selective targeting of lipid-rich tissues|
|US20040068255 *||Oct 7, 2002||Apr 8, 2004||Short Kenneth Lawrence||Methods of operating a photo-thermal epilation apparatus|
|US20040073079 *||Jun 19, 2003||Apr 15, 2004||Palomar Medical Technologies, Inc.||Method and apparatus for treatment of cutaneous and subcutaneous conditions|
|US20040082941 *||Oct 16, 2003||Apr 29, 2004||Connors Kevin P.||Tissue treatment device and method|
|US20040116984 *||Dec 5, 2003||Jun 17, 2004||Greg Spooner||Method and system for controlled spatially-selective epidermal pigmentation phototherapy with UVA LEDs|
|US20040143247 *||Oct 31, 2003||Jul 22, 2004||Anderson R. Rox||Method and apparatus for treating wrinkles in skin using radiation|
|US20040147986 *||Jan 24, 2003||Jul 29, 2004||Baumgardner Jonathan M.||Method and apparatus for treating skin disorders using a near black body flashlamp source|
|US20040162549 *||Nov 12, 2003||Aug 19, 2004||Palomar Medical Technologies, Inc.||Method and apparatus for performing optical dermatology|
|US20040176824 *||Mar 3, 2004||Sep 9, 2004||Weckwerth Mark V.||Method and apparatus for the repigmentation of human skin|
|US20040199227 *||Feb 10, 2004||Oct 7, 2004||Altshuler Gregory B.||Biostimulation of the oral cavity|
|US20040236267 *||Feb 26, 2004||Nov 25, 2004||Advanced Light Technology, Llc, A Corporation Of The State Of California||Disinfection, destruction of neoplastic growth, and sterilization by differential absorption of electromagnetic energy|
|US20050180140 *||May 7, 2003||Aug 18, 2005||George David S.||Intense pulsed light devices|
|US20050256515 *||Jun 8, 2005||Nov 17, 2005||Anderson R R||Method and apparatus for treating wrinkles in skin using radiation|
|US20060089687 *||Nov 14, 2005||Apr 27, 2006||Greg Spooner||System for controlled spatially-selective epidermal pigmentation phototherapy with UVA LEDs|
|US20060111760 *||Dec 28, 2005||May 25, 2006||Lajos Kemeny||Phototherapeutical method and system for the treatment of inflammatory and hyperproliferative disorders of the nasal mucosa|
|US20060122585 *||Nov 2, 2005||Jun 8, 2006||Acme Medical, Inc.||Tissue treatment system|
|US20070038206 *||May 1, 2006||Feb 15, 2007||Palomar Medical Technologies, Inc.||Photocosmetic device|
|US20070239142 *||May 1, 2006||Oct 11, 2007||Palomar Medical Technologies, Inc.||Photocosmetic device|
|US20070255265 *||Apr 28, 2006||Nov 1, 2007||Davenport Scott A||Localized flashlamp skin treatments|
|US20090137995 *||Sep 22, 2008||May 28, 2009||Palomar Medical Technologies, Inc.||System For Electromagnetic Radiation Dermatology And Head For Use Therewith|
|US20090149844 *||Sep 15, 2008||Jun 11, 2009||Palomar Medical Technologies, Inc.||Method And Apparatus For Improved Vascular Related Treatment|
|US20110036983 *||Nov 27, 2008||Feb 17, 2011||Ford Timothy D F||Identification system and method using highly collimated source of electromagnetic radiation|
|US20110202115 *||Aug 18, 2011||Panasonic Electric Works Co., Ltd.||Hair growth modulation device|
|USRE36634 *||Sep 5, 1996||Mar 28, 2000||Ghaffari; Shahriar||Optical system for treatment of vascular lesions|
|EP0142671A1 *||Sep 20, 1984||May 29, 1985||Carol Block, Ltd.||Method and apparatus for photoepilation|
|EP0565331A2 *||Apr 5, 1993||Oct 13, 1993||ESC Medical Systems Ltd.||Therapeutic electromagnetic treatment|
|EP0736308A2 *||Mar 20, 1996||Oct 9, 1996||ESC Medical Systems Ltd.||Method and apparatus for depilation using pulsed electromagnetic radiation|
|EP0788814A2||Feb 7, 1997||Aug 13, 1997||ESC Medical Systems Ltd.||Depilation using pulsed electromagnetic radiaton|
|EP0885629A2 *||Jun 15, 1998||Dec 23, 1998||Danish Dermatologic Development A/S||Light pulse generating apparatus and cosmetic and therapeutic phototreatment|
|EP1078604A2 *||Apr 5, 1993||Feb 28, 2001||ESC Medical Systems Ltd.||Device for therapeutic electromagnetic treatment|
|EP1078605A2 *||Apr 5, 1993||Feb 28, 2001||ESC Medical Systems Ltd.||Device for therapeutic electromagnetic treatment|
|EP1230900A1 *||Jan 31, 1996||Aug 14, 2002||The General Hospital Corporation||Hair removal apparatus using optical pulses|
|EP2316372A1 *||Jan 25, 2001||May 4, 2011||Palomar Medical Technologies, Inc.||Method and apparatus for medical treatment utilizing long duration electromagnetic radiation|
|WO1986005676A1||Apr 1, 1986||Oct 9, 1986||Eugene Jim Politzer||Method and apparatus for shaving the beard|
|WO1993008715A1 *||Oct 28, 1992||May 13, 1993||Thermotrex Corp||Hair removal device and method|
|WO1997035526A1||Feb 11, 1997||Oct 2, 1997||Iain D Miller||Method and apparatus for hair removal|
|WO1997037602A2 *||Apr 4, 1997||Oct 16, 1997||George Cho||Alexandrite laser system for treatment of dermatological specimens|
|WO1998025673A1 *||Dec 10, 1996||Jun 18, 1998||Lucid Tech Inc||Epilation system|
|WO1999032193A1||Dec 23, 1998||Jul 1, 1999||Shimon Eckhouse||Apparatus for therapeutic electromagnetic treatment|
|WO2006120635A2||May 8, 2006||Nov 16, 2006||Koninkl Philips Electronics Nv||Hair-growth control device and hair-growth control method|
|U.S. Classification||606/9, 606/3, 606/15, 606/11|
|International Classification||A61B18/18, A45D26/00, A61B18/20, A61N5/06|
|Cooperative Classification||A61B18/203, A45D26/00, A61B2018/00452, A61B2018/00476, A61B2018/1807, A61N2005/0662|
|European Classification||A61B18/20H, A45D26/00|