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Publication numberUS3715189 A
Publication typeGrant
Publication dateFeb 6, 1973
Filing dateJun 15, 1970
Priority dateJun 15, 1970
Publication numberUS 3715189 A, US 3715189A, US-A-3715189, US3715189 A, US3715189A
InventorsS Nighohossian, J Tobin
Original AssigneeSecretary Of The Treasury
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Qualitative analysis device
US 3715189 A
A qualitative analysis device which allows for the performance of a qualitative analysis for cannabis material in vegetable matter which required a performed extraction step followed by a reaction step. The device has an outer container and an inner container within the outer container. The inner container has a frangible section and is also provided with a means for breaking the frangible section. The device is sealable so that the reagents may be stored within the device and be ready for use at any time.
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Description  (OCR text may contain errors)

United States Patent [191 Nighohossian et al.

[ 1 Feb. 6, 1973 [54] QUALITATIVE ANALYSIS DEVICE [75] Inventors: Sarkie Nighohossian, Baltimore; John J. Tobin, Jr., Hyattsville, both of Md.

[73] Assignee: The United States of America as represented by the Secretary of the Treasury [22] Filed: June 15, 1970 [211 App]. No.: 46,365

[52] US. Cl. ..23/259, 23/230 R, 23/230 M, 23/253 R, 23/292, 206/47 A, 215/6 [51] int. Cl ..G01n 1/10, 865d 81/00, B65d 79/00 [58] Field of Search ..23/230, 253, 259, 292; 206/47 A; 215/6; 220/89 [56 References Cited UNITED STATES PATENTS 5/1969 Salivar et al. ..23/253 R 11/1969 Johnson et al. ..23/253 R 3,480,398 11/1969 Hamilton ....23/259 X 3,497,320 2/1970 Blackburn ..23/230 3,504,376 3/1970 Bednar et al. .....23/230 3,545,935 12/1970 Kearns ..23/292 3,582,283 6/1971 Mirasol Jr ..23/292 X Primary ExaminerMorris O, Wolk Assistant Examiner-R. E. Serwin Attorney-Thomas Hayward Brown, Joseph A. Hill and A. David Spevack [57] ABSTRACT 1 Claim, 7 Drawing Figures PATENTED FEB 6 I975 0 I 5 R M s N a Q WWW HB ta mm I N J 4 E y F SJ A d v M 7 Y B 8 2 5 m F o o 5 M 0 4 I N F m ATTORNEY QUALITATIVE ANALYSIS DEVICE I GOVERNMENT LICENSE The invention described herein may be manufactured and used by or for the Government of the United States of America for Governmental purposes without the payment of any royalties thereon or therefor.

This invention pertains to a qualitative analysis device and more particularly pertains to a qualitative analysis device which allowsfor the serial extraction and reaction of vegetable matter to determine if the vegetable matter contains cannabis material.

BACKGROUND OF THE INVENTION At the present time the use of marijhauna, hashish or hemp-type hallucinagenic drugs is illegal in the United States. Law enforcement offices are often faced with a problem in the performance of their duties of determining, under field conditions, whether suspected vegetable matter in fact contains cannabis material and therefore is within the scope of the regulations pertaining to the possession of marijhauna. There are known qualitative organic tests which can be applied to vegetable matter in order to detect if there are cannabinols components within the vegetable matter. The term cannabinols is used herein in a collective sense and refers to Cannabidiol, Tetrahydrocannabinol, Cannabinol and Cannabidiolic Acid. These substances are the important constituents in marijhauna.

One test commonly used is the Duquenois-Levine color test wherein the suspected vegetable matter is first extracted in Duquenois reagent and then treated with concentrated hydrochloric acid. If marijhauna or one of the' derivatives is present, a blue to violet color can be extractedinto chloroform. At present this qualitative test is performed, even under field conditions, by providing the three reagents in separate flasks or vials. A field agent must handle all three vials and follow the instructions of first extracting in the Duquenois reagent then pouring the resultant mixture into the hydrochloric acid reagent and finally extracting with the chloroform. This procedure is clumsy and inconvenient.

It is therefore an object of this invention to provide a qualitative analysis device for conducting the Duquenois-Levine color test in one apparatus.

It is also an object of this invention to provide a qualitative analysis device which is easily portable and simply used either under field or laboratory conditions.

An additional object of this invention is to provide a qualitative analysis device which allows for the serial conduction of qualitative tests involving extraction of a material and a subsequent reaction step.

Yet another object of this invention is to provide a qualitative analysis device having a frangible member.

Other objects of this invention will become apparent in the following description.

Devices have appeared in the prior art which utilized a frangible or separable member for selectively releasing one reactant into another reactant. Grosskopf in US Pat. No. 2,709,127 describes a device which provides a color test kit for detecting certain acid esters in a gas or vapor train. The device is basically a tube sealed at both ends which contains a reacting material supported on a resin, an indicator supported on filter paper and a developing solution contained in a frangible container. In operation the ends of the Grosskopf device are broken off and the gas train passed through the tube. Then the developing solution (water) is released by breaking the frangible container. This developing solution flows through the filter paper containing the indicator and over the resin thereby completing the test.

Although Grosskopf describes a device which contains a frangible element, the device does not allow for the serial extraction of vegetable matter and subsequent reaction and color development of the extracted liquor. Buchoff, in US. Pat. No. 2,929,687, discloses a simple device for testing boiler water which includes a small container mounted within a larger container. The small container is filled with a test liquid and then is sealed by placing a metal ball at its top. The outer container is filled with the liquid to be tested and sealed; the entire device is then inverted, causing the ball to drop off, releasing the testing solution contained within the inner container. These devices are exemplary of existing qualitative analysis devices.

SUMMARY OF THE INVENTION This invention contemplates a qualitative analysis device having an outer container and an inner container wherein the inner container has a frangible section, and a fracturing means associated with the inner container.

BRIEF DESCRIPTION OF DRAWING FIG. 1 is an elevation section of the device.

FIG. 2 (a) through (c) is a depiction of sequential steps of the device in use.

FIG. 3 is a general perspective view of the device.

FIG. 4 is an alternate construction of the plunger piston of the device.

FIG. 5 is a second alternate construction for the plunger piston of the device.

DESCRIPTION OF THE PREFERRED EMBODIMENTS The qualitative analysis of this invention has an outer container which has an opening therein and an inner container which is positioned and firmly held in the opening of the outer container. The inner container is substantially contained within the outer container but is spaced apart, on at least one face, from said outer container so that at least one wall of the inner container does not touch the walls of the outer container. The inner container has a cap which can be removed to close and seal the inner container and at least a section of the inner container is frangible. A fracturing means is positioned in the inner container in such a manner that it may selectively fracture the frangible section when desired.

The container is so designed that it will both allow for the performance of the serial steps of the Duquenois-Levine color test without having to handle separate reagent containers and, in addition, it will act as a portable storage container for the reagents. The device of this invention takes many forms and may be assembled from a number of differently shaped components falling within the following guidelines. The outer container is transparent to the extent that a change in color taking place within the device would be visible. The outer container can be of any shape but must have an opening in at least one side thereof to allow the inner container to be inserted therethrough. This may be done by having the inner container actually sealed to the outer container once the reagents for the outer container are in place or more preferably a tight fitting cap can be used to close the outer container wherein the cap contains an opening therein wherein the inner container may be mounted and affixed. The outer container may be made of any materials which will not interact with the reagents contained therein and are sufficiently stable to withstand the shock of transport. Such materials are glass, plastic and non-woven coated fabrics. The inner container may be made of any material which will not interact with the reagents contained therein or interfere with the reaction to be performed therein. The inner container should be of sufficiently strong material that allows for safe manipulation during the test. The inner container should have at least one frangible section. In the preferred embodiment the inner container is made of glass and a bottom portion of said glass container is of extremely thin construction so that it may easily be fractured. In an alternate embodiment the inner container can be a simple glass or plastic tube having a frangible plastic membrane or film across one end positioned so that it may be easily fractured or torn. It is not necessary for the inner container to be transparent and the inner container can also be manufactured from metal and metal foil or similar material as long as said metal is coated with a substance which prevents the interaction of the reagents with the container.

The fracturing means can include any device which can be inserted into the inner container to break the frangible section of the inner container. In its preferred form the fracturing device is a piston plunger which also works in cooperation with the closure of the inner container to seal the inner container and prevent loss of material in storage. The fracturing means may be constructed of any material which will not interact with the reagents contained within the device and will provide a slidable seal for the inner container. In its preferred embodiment, the fracturing means is a plunger piston made of plastic or synthetic material such as polyethylene polypropolyene or nylon which can have sufficient stiffness to act as a plunger and yet be sufficiently self lubricating to allow for the plunger to slidably seal the inner container. The plunger piston may be the only seal for the inner container but, most preferably, the plunger piston is mounted in the inner container closure. The closure is provided with a guideway for the plunger piston to increase the stability and safety of the device. The device is also provided with a protective cap of any one of the types commonly used in the aerosol and pump bottle art to protect the plunger assembly during storage and transport and to prevent the unintentional depression of the plunger thereby breaking the frangible seal before it is desired to do so. These protective caps include such devices as twist-off caps used on the liquid soap pump bottles and snap-off caps as are commonly used on aerosol shave creams.

Now having generally described the qualitative analysis device of this invention, reference is made to the drawings to describe specific embodiments of the invention which are illustrative of the device when made of glass.

Referring now to the drawings, FIG. 1 is an elevation of the qualitative analysis device 10, having an outer container 11 with closure 12. Closure 12 is securely attached to container 11 by means of detent 13. In an alternate embodiment (not illustrated) closure 12 can be threadably secured to container 11.

A second container 14 is securely affixed to closure 12 by means of shoulder 15 integrally formed on container 14 and threaded nut 16. Nut 16 is provided with outer threads 17 which provide a means for securing protective cap 18 to the device 10. The bottom of inner container 14 is a frangible section 22.

A piston plunger 19, having plunger handle 20 and piston head 21, is slidably positioned in container 14 in such a manner that piston head 21 seals inner container 14.

Plunger handle 20 is of sufficient length that piston 21 exerts force on liquid contained in container 14 to an extent sufficient to fracture section 22 when plunger 20 is depressed.

As illustrated, container 14 is spaced apart from container 11 on all sides. In actuality side walls 23 of container 14 can be spaced adjacent to side walls 24 of container 11 with just sufficient room-between containers 11 and 14 to allow for easy insertion of container 14 into container 11.

It is required that sufficient space be provided between the frangible section of the inner container and the outer container adjacent the frangible section to both contain the quantities of reagents used and allow for the fracturing of the frangible section. Of course, with glass construction it is only necessary to score the container sufficiently that a part of the container will break when force is exerted.

Referring again to FIG. 1 approximately one milliliter of Duquenois solution 26 is placed in container 14 and slightly in excess of one milliliter each of chloroform 27 and hydrochloric acid 28 is placed in container 1 l. Sufficient head room is provided between frangible section 22 and the surface of the hydrochloric acid 28 to contain the contents of container 14 during the test.

In an alternate embodiment illustrated in FIG. 5, piston head 521 is provided with blades 500 which aid in the fracturing of the frangible section.

Another arrangement is illustrated in FIG. 4 where container 411 is substantially cylindrical and is threaded at the top. Inner container 414 is suspended by shoulders 415 within container 411. Screw cap 416 seals both inner container 414 and outer container 416 and holds these containers together in position. Plunger 420,having a pointed end 421,is slidably mounted in collar 401 surrounding opening 402 in closure 416 and is of sufficient length so as to pierce frangible section 422 when depressed. A protective cap 418 is provided to protect the device and prevent the accidental activation of the plunger 420. In its preferred form the device, as illustrated in FIG. 4 is formed from plastic.

FIG. 3 is a perspective view of device 10 ready for use or storage. Protective cap 18 is in place and outer container 11 is charged with chloroform 27 and hydrochloric acid 28. Container 14 is charged with Duquenois reagent. In the preferred embodiment approximately 1 milliliter of Duquenois agent is placed in the inner container and slightly in excess of one milliliter each of chloroform and hydrochloric acid are placed in the outer container. It is only necessary to use equal portions of hydrochloric acid and chloroform to the quantity of Duquenois reagent used but in practice it is preferrable to use a slight excess of hydrochloric acid and chloroform.

Duquenois reagent is a mixture of vanillin, acetaldehyde and ethanol (95 percent). The chloroform is reagent grade material and the hydrochloric acid is concentrated reagent grade material.

The chloroform and hydrochloric acid are immiscible and will remain in two layers in the outer container with the hydrochloric acid layer on top. Once the chloroform and hydrochloric acid are placed in the outer container the outer container may be either permanently sealed or provided with a tight fitting removable cover. The Duquenois solution is placed in the inner container. This device, as seen in FIG. 3 fully set up, may be stored for extended periods of time or easily transported with field agents so that it may be used in the field when necessary. The operation of the device will be demonstrated by referring to FIG. 2 (a)(c). When it is necessary to use the device in the field, the outer protective cap 18 is removed and discarded. Piston plunger 20 is removed and the suspected vegetable matter 250 is dropped into the Duquenois solution 26 contained in container 14 as is seen in FIG. 2. The plunger 20 is then replaced thereby sealing the vegetable matter into container 14. Device is shaken to allow the Duquenois reagent 26 to extract the cannibus material from vegetable matter 250. Then plunger is depressed causing piston 21 to exert pressure on Duquenois solution 26 which in turn exerts the pressure against the frangible section 22 of container 14 fracturing said section 22 as is seen in FIG. 2b. The vegetable matter 250 and Duquenois reagent 26, now containing any extracted matter, is dumped into the hydrochloric acid layer 28 contained in container 11. Device 10 is then swirled to allow an interaction of the hydrochloric acid 28 with any cannibus material extracted into the Duquenois reagent 26. Lastly, unit 10 is shaken to extract any formed color from the hydrochloric acid layer into the chloroform layer 27. A positive test is illustrated in FIG. 20 by the violet color extracted into the chloroform layer 27.

This device provides a simple-to-use compact and readily available unit for the identification of marijhauna or marijhauna-type products by law enforcement officers and others either in the field or in the laboratory. The relatively tight fit of the closure and inner container and the relatively narrow vapor space between the outer container and the inner container reduces the vaporization and loss of both the chloroform and hydrochloric acid which are both relatively volatile materials. In field tests this device has proved usable in the field, even on the Texas border at temperatures up to F. The device provides a simple unitary structure for accomplishing a reaction sequence which can be rather complicated for one not skilled in chemical techniques. 5

Although the invention has been particularly disclosed for a device constructedout of glass, it is to be understood that the invention IS applicable for other materials such as plastics. It is also obvious to one of ordinary skill in the art that the foregoing is presented by way of example only and the invention is not to be unduly restricted thereby since modifications may be made in the structure of the various parts without functionally departing from the spirit of this invention.

What I claim is:

l. A self-contained device for performing qualitative analysis comprising:

an outer container open at one end;

a closure having an inner container affixed thereto for sealing said outer container;

said inner container positioned in the opening of said outer container, said inner container. being substantially contained within said outer container and spaced apart from said outer container on at least one face thereof, said inner container having a frangible section;

a removable plunger piston for slidably sealing said inner container, said plunger piston being of sufficient length so as to exert a force on liquid contained in said inner container sufficient to fracture said frangible section when said plunger is depressed;

said inner container containing Duquenois reagent and said outer container containing chloroform and hydrochloric acid, each in an amount slightly in excess of the amount of Duquenois reagent present; and

a protective cap placed over said plunger piston to prevent the accidental depression of said plunger piston.

* i k i

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US3446596 *Apr 2, 1965May 27, 1969Mallinckrodt Chemical WorksAnalytical package and method
US3476515 *Apr 26, 1966Nov 4, 1969Du PontAnalytical test pack and process for analysis
US3480398 *Dec 26, 1967Nov 25, 1969Xerox CorpChemical package
US3497320 *Dec 15, 1966Feb 24, 1970Xerox CorpAutomated chemical analyzer
US3504376 *Dec 15, 1966Mar 31, 1970Xerox CorpAutomated chemical analyzer
US3545935 *Nov 22, 1968Dec 8, 1970Xerox CorpDisposable reaction container for an automatic chemical analyzer
US3582283 *Mar 25, 1970Jun 1, 1971Xerox CorpChemical package
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3856169 *Jul 5, 1973Dec 24, 1974Cutts RApparatus for collection of sediment in bottled fluids
US3860114 *Jun 18, 1973Jan 14, 1975Merckardt VolkerMulti-chamber container
US3894845 *May 24, 1973Jul 15, 1975Bernard McdonaldUrine collection and analysis device
US3970068 *May 15, 1975Jul 20, 1976Shotaro SatoHeat exchange package for food
US3990683 *Dec 24, 1974Nov 9, 1976Reichhold Chemicals, Inc.Packaging means
US4020832 *Dec 24, 1974May 3, 1977Reichhold Chemicals, Inc.Package and method for preparing orthopedic cast-making materials
US4066407 *Dec 16, 1976Jan 3, 1978Vincent LupicaCapillary pipette, multicell container and timer
US4193698 *Feb 7, 1979Mar 18, 1980Veit GartnerDevice for rupturing a frangible partition between separate chambers in a container
US4196167 *Dec 26, 1978Apr 1, 1980California Medical Developments, Inc.Drug detection device
US4252538 *Mar 2, 1979Feb 24, 1981Engineering & Research Associates, Inc.Centrifuging
US4253773 *Aug 20, 1979Mar 3, 1981Minnesota Mining And Manufacturing CompanyFluid container
US4315570 *Dec 26, 1979Feb 16, 1982Jules SilverTwo-compartment container with means for dispersing contents of one compartment into the other compartment
US4324758 *Apr 18, 1980Apr 13, 1982The United States Of America As Represented By The Secretary Of The Air ForceAnalysis of lubricating oils for iron content
US4404170 *Apr 23, 1982Sep 13, 1983The United States Of America As Represented By The Secretary Of The NavyForces reactant cylinder into reactant or non-reactant liquid
US4623373 *Feb 15, 1985Nov 18, 1986At&T Bell LaboratoriesTechnique for fabricating a gas-in-glass fiber
US4653337 *Feb 3, 1986Mar 31, 1987Metal Box P.L.C.Containers for use in detecting micro-organisms
US4657534 *Nov 4, 1985Apr 14, 1987Alcon Laboratories, Inc.Dual compartment, disposable, mixing and dispensing container
US4663127 *Oct 15, 1982May 5, 1987Hemotec, Inc.Gas flow cartridge having resilient flexible membrane with slit separating reaction and reagent chambers
US4686192 *Sep 2, 1983Aug 11, 1987Electric Power Research Institute, Inc.Method for detecting impurities in an oil sample
US4917254 *Apr 17, 1989Apr 17, 1990Ciriacks Brian LSanitary disposable container
US4944921 *Mar 6, 1984Jul 31, 1990Maxwell LaboratoriesAutomated PCB analyzer system
US5174961 *Jan 18, 1991Dec 29, 1992Hemotec, Inc.With separately controlled automatic dispenser subassembly
US5176634 *Aug 2, 1990Jan 5, 1993Mcgaw, Inc.Flexible multiple compartment drug container
US5200149 *Jul 18, 1990Apr 6, 1993Electric Power Research Institute, Inc.Chemical test kit for use in detecting impurities in oil samples
US5240861 *Jul 29, 1988Aug 31, 1993Spectrum Medical Industries, Inc.Device and process for concentrating biologic specimens in liquid form
US5284621 *Sep 10, 1992Feb 8, 1994Kaufman Jack WWaste fluid disposal aid
US5318183 *Nov 4, 1992Jun 7, 1994Glaxo, Inc.Bottle with insert to reduce effective volume
US5322165 *Feb 16, 1993Jun 21, 1994University Of FloridaSharp instrument encasement system
US5344780 *Aug 20, 1991Sep 6, 1994Ulf NonboeMethod for determining indole compounds associated with boar taint in pork as well as a sample container to be used in the method
US5445965 *Jun 8, 1994Aug 29, 1995Hybrivet Systems, Inc.Detection of nutrients and contaminants in liquid sample
US5449494 *Jun 30, 1992Sep 12, 1995Amersham International Plc.Cylindrical tube with plunger, reagent sealed in tube
US5496736 *May 17, 1995Mar 5, 1996Hybrivet Systems, Inc.Process for testing for substances in liquids
US5525299 *Aug 13, 1993Jun 11, 1996Lowe; Henry E.Container closure
US5658531 *Oct 29, 1992Aug 19, 1997The University Of BirminghamAssay device
US5772017 *Oct 25, 1996Jun 30, 1998Kang; Heung SunFor a bottle
US6149866 *Jun 18, 1997Nov 21, 2000Orion-Yhtyma OyjA closure device which can render the reagent used in bioassay of biological fluid such as blood, into a state assuring a reliable test result and is able to maintain storage stability of the reagent under adverse conditions
US6152296 *Nov 6, 1998Nov 28, 2000Shih; Kuang-ShengAdditive holder for a pet bottle
US6168758 *Nov 19, 1997Jan 2, 2001Starplex ScientificLiquid sample assay device
US6343718Oct 15, 1998Feb 5, 2002Loctite CorporationUnit dose dispense package
US6372270 *May 16, 2000Apr 16, 2002Sean P. DennyDrink mix apparatus for making personal quantities of beverage
US6598762Jan 22, 2002Jul 29, 2003Affinity Management Solutions, Inc.Coating touch up kit
US6641782 *Nov 15, 2000Nov 4, 2003Polaroid CorporationApparatus for performing diagnostic testing
US6740294 *Apr 16, 2001May 25, 2004Macherey, Nagel Gmbh & Co.Analyzing vapor forms of a sample; insert sample into receptacle, mix with tracer, eject into analysis receptacle, monitor evolved vapor
US6805844 *Mar 3, 2000Oct 19, 2004Tennessee Valley AuthoritySingle-use vessel for holding frangible container of toxic material and treatment chemical, having upper compressible section, cover, jack and impact member on cover; upon compression impact member breaks container, releasing material
US6820740 *Jun 18, 2003Nov 23, 2004Donald SpectorUniversal cap for dispensing materials by retrofit upon existing bottled beverage containers
US6854595 *Jul 15, 2002Feb 15, 2005Danny KiserSeal for the lower end of the storage compartment; plunger to unseal the seal to allow interaction between the mix and liquid; particularly beverage containers
US6878338May 6, 2002Apr 12, 2005Prismedical CorporationComprises housing, diluent, reagent bed, wherein diluent and reagent bed are separated by friable barrier and a flow distribution disk; maintaining each component separately prior to use
US7249690Dec 24, 2004Jul 31, 2007Erie County Plastics CorporationIndependent off-bottle dispensing closure
US7303328 *May 20, 2004Dec 4, 2007C.R.F. Societa Consortile Per AzioniDisposable cartridge for mixing exothermic or endothermic reaction substances, and relative cartridge-support assembly
US7506782Dec 24, 2004Mar 24, 2009Ronald J WaltersSingle use unit dosage dispensing closure
US7645424May 16, 2006Jan 12, 2010O'donovan MichaelReagent cuvette
US7686188Dec 21, 2004Mar 30, 2010Berry Plastics CorporationDrain-back spout fitment closure with drip-less pour tip
US7767447Dec 12, 2008Aug 3, 2010Gen-Probe IncorporatedInstruments and methods for exposing a receptacle to multiple thermal zones
US7780336Dec 12, 2008Aug 24, 2010Gen-Probe IncorporatedInstruments and methods for mixing the contents of a detection chamber
US7793655Jul 11, 2005Sep 14, 2010Boehringer Ingelheim Pharma Gmbh & Co. KgTwo-chamber cartridge for propellant-free metering aerosols
US7971454 *Jul 28, 2008Jul 5, 2011Datacolor Holding AgBeaker type dyeing machine
US7980243 *Jun 7, 2007Jul 19, 2011Boehringer Ingelheim Pharma Gmbh & Co., KgTwo-chamber cartridge for propellant-free metering aerosols
US8048375Dec 12, 2008Nov 1, 2011Gen-Probe IncorporatedGravity-assisted mixing methods
US8052929Apr 1, 2011Nov 8, 2011Gen-Probe IncorporatedGravity-assisted mixing methods
US8480976Jul 13, 2011Jul 9, 2013Gen-Probe IncorporatedInstruments and methods for mixing the contents of a detection chamber
US8491178Mar 7, 2012Jul 23, 2013Gen-Probe IncorporatedInstruments and methods for mixing the contents of a detection chamber
US8642323 *Jan 17, 2012Feb 4, 2014Zyzeba Testing LimitedContainer for testing for micro-organisms
US8714808 *Aug 22, 2005May 6, 2014Yoshino Kogyosho Co., Ltd.Container for mixing two fluids
US8735055Dec 12, 2008May 27, 2014Gen-Probe IncorporatedMethods of concentrating an analyte
US20110076662 *Dec 7, 2010Mar 31, 2011Spangler Steven DApparatus and method for a solid catalyst and fluid dynamic eruption reaction
US20110318843 *Dec 14, 2009Dec 29, 2011Abraham Robert De KrakerDevice for evaluating a heat exchange fluid
US20120107811 *Feb 5, 2010May 3, 2012Kelso David MBurstable liquid packaging and uses thereof
US20120115216 *Jan 17, 2012May 10, 2012Zyzeba Testing LimitedContainer for testing for micro-organisms
EP0024132A1 *Jul 24, 1980Feb 25, 1981Minnesota Mining And Manufacturing CompanyFluid container
EP0029361A2 *Nov 14, 1980May 27, 1981Robert Charles TurnerLiquid sample collector device
EP0746754A1 *Jun 9, 1992Dec 11, 1996Prisma Systems CorporationCuvette for automated testing machine
EP0838025A1 *Jul 12, 1996Apr 29, 1998Immunological Associates of DenverSelf-contained device integrating nucleic acid extraction, amplification and detection
EP1390466A1 *Apr 26, 2002Feb 25, 2004Boston Biomedica, Inc.Multichamber device and uses thereof for processing of biological samples
WO1987001614A1 *Sep 16, 1985Mar 26, 1987Schumacher Co J CVacuum vapor transport control
WO1989010561A1 *Apr 27, 1989Nov 2, 1989Plastik Grunenberg Gmbh TProcess and device for the qualitative and quantitative analysis of nitrate ions
WO1993000994A1 *Jun 30, 1992Jan 21, 1993Amersham Int PlcSampling device
WO1993009431A1 *Oct 29, 1992May 13, 1993Univ BirminghamAssay device
WO2002010032A2 *Jul 27, 2001Feb 7, 2002Cambridge Life SciencesStorage devices and associated apparatus
WO2002089960A2 *May 6, 2002Nov 14, 2002Carolyn FitzgeraldDual chamber dissolution container with passive agitation
WO2005049207A1 *Nov 18, 2004Jun 2, 2005Michael O'donovanA reagent cuvette
WO2005056402A1 *Dec 7, 2004Jun 23, 2005Bochtler MartinSystem for combining liquids
WO2011054086A1 *Nov 3, 2010May 12, 20117685297 Canada Inc.Systems and methods for preparing samples for chemical analysis
U.S. Classification422/413, 215/6, 206/219, 436/165, 422/236, 436/901, 436/92, 206/222, 422/430
International ClassificationB01L3/00
Cooperative ClassificationY10S436/901, B01L3/502
European ClassificationB01L3/502