|Publication number||US3728213 A|
|Publication date||Apr 17, 1973|
|Filing date||Aug 18, 1971|
|Priority date||Aug 18, 1971|
|Publication number||US 3728213 A, US 3728213A, US-A-3728213, US3728213 A, US3728213A|
|Original Assignee||American Cyanamid Co|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (32), Classifications (15)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent 1191 Hinz 1 221 Filed:
[ ANTIBIOTIC PAPER  Inventor: Charles Frank Hinz, East Norwalk,
[73'] Assignee: American Cyanamid Company, Stamford, Conn.
Aug. 18, 1971  Appl. No.: 172,880
Related US. Application Data  Continuation-impart of Ser. No. 773,954, Nov. 6, I968, abandoned, and a continuation-in-part of Ser. No. 42,479, June 1, 1970, abandoned.
 U.S.-Cl. ..162/l6l, 47/9, 162/158, i 424/28, 424/322  Int. Cl. ..D2lh 5/22, D21h 3/12  Field of Search ..162/158, 161,190; 424/322, 326, 2729  References Cited UNITED STATES PATENTS 2,923,656 2/l960 Hackman ..424/322X 2,980,734 4/1961 Kosmin ..424/322 x 3,060,079 l0/l962 PamnOCh 162/161 3,483,296 12/1969 Martin ..l62/l61 x FOREIGN PATENTS OR APPLICATIONS 618,089 4/1961 Canada 162/161 Primary Examiner-S. Leon Bashore Assistant Examiner'-Wi11iam F. Smith Attorney-Evans Kahn 5 7] ABSTRACT 7 Claims, No Drawings ANTIBIOTIC PAPER This is a continuation-in-part of my copending applications, Serial Nos. 773,954 and 42,749, respectively, filed November 6, 1968 and June 1, 1970, and now both abandoned.
The present invention relates to cellulose fibers and fibrous cellulose structures having antimicrobial properties. More particularly, the invention relates to cellulose fibers, water-laid cellulose webs (including paper) and articles made therefrom having antimicrobial properties resulting from the presence therein of a uniformly adsorbed content of an ionic pseudourea, and to methods for the manufacture of said fibers and webs. For convenience, the term antimicrobial is hereafter used to describe the inhibiting of the life of all microbes including fungi, bacteria, protozoa and viruses.
Antimicrobial paper is paper composed of fibers which have an effective content of an agent which inhibits the growth thereon of some or all of the forms of life just mentioned. In the past, the principal use of such paper has been as mulch paper (paper which is spread on the ground to inhibit the growth of weeds and the evaporation of water), but such paper is coming to find important use for such purposes as handages, boxes for bandages and other surgical equipment, diapers, surgical drape sheets, hospital gowns and bed sheets, and as the base for surgical adhesive tape. Such items are commonly supplied in sterile form, and during their period of use they must resist microbial growth. Paper which possesses antiviral properties is urgently desired, for example in connection with the care of patients with head colds, influenza and mumps.
Because of the long period of time during which it must maintain its integrity in the warmth and humidity of the environment, mulch paper must be highly and comparatively permanently resistant tomicrobial attack. Mulch paper is moist during much of its life at a temperature most favorable to the growth of microorganisms, andis subject to severe tearing forces (e.g., by
t the wind) from time to time. Mulch paperdesirably maintains its identity and strength during the growing season and nevertheless should ultimately succumb to attack by microorganisms, i.e., it should be greatly weakened or disintegrated by them within two to three months after being plowed under ground at the end of the growing season. PaPer used for bandages, hospital outdoor weathering. l have found that in preferred embodiments such as when the paper is sufficiently antimicrobial to strongly resist the growth of microbial life under incubating conditions, the fibers carrying a pseudourea of the type described remain substantially sterile.
The present invention in preferred embodiments provides improvements as follows:
respect to yeasts, bacteria, protozoa, and lipophilic viruses. 2. Paper comprising the aforesaid fibers possesses similar antimicrobial properties and remains substantially sterile when employed as diaper material for babies, surgical drape sheets, hospital gowns bed sheets, etc.
3. The paper strongly resists attack by microorganisms found in agricultural fields, and this activity is not masked when the paper has an effective amount of a normally water-soluble wet strength resin in thermoset state. Moreover, the paper is readily permeable by water, and hence permits rain to penetrate into the ground, and is accordingly well-suited for use as mulch paper. The paper is substantially unaffected by the action of microorganisms when allowed to remain for three to five months on fields under temperature and humidity conditions highly conducive to the rapid growth of microorganisms (temperatures of F. F. and relative humidity in excess of 50 percent).
The microbial life against which the paper of the present invention possesses activity include the bacteria, (including sulfate-reducing bacteria), yeasts, fungi, and green algae, and lipophilio viruses.
The pseduoureas referred to have the formula alkyl substituents include octyl, dodecyl, hexadecyl and 1 octadecyl. The aforesaid pseudoureas dissolve in water containing a stoichiometric excess of hydrochloric acid,'acetic acid, formic acid, trichloroacetic acid,
nitric acid, phosphoric acid or other strong acid. The molecule as awhole is cationic.
The amount of pseudourea present in cellulose fibers and in the paper of the present invention depends upon the specific antimicrobial activity of the pseudourea present, the vitality of the microorganisms present, and the degree of antimicrobial activity which it is desired that the fibers (or paper, paperboard, etc. which have a content thereof) should possess. As a rule of thumb, I have foundthat in most instances, cellulose fibers possess perceptible antimicrobial activity when they contain as little as 0.1 percent of the pseudourea based on the dry weight of the fibers. On the other hand, I have found that the fibers need not contain more than about 3 percent by weight of the pseudourea for them to possess very satisfactory antimicrobial activity. .My results to date indicate that satisfactory results are obtained when the fibers contain between about 0.3 percent and 0.5 percent by weight of the pseudourea as in this range the fibers (and the paper) possess very satisfactory antimicrobial activity yet over-use of the pseudourea. is avoided. The optimum amount of pseudourea that need be present in any instance to procure the desired antimicrobial activity can be readily found by laboratory trial.
The pseudoureas referred to above are most conveniently applied by forming an aqueous suspension of cellulose fibers and adding to the suspension one or more of the aforesaid pseudoureas as a water-soluble salt. The pseudourea component of the salts are rapidly and substantively absorbed by the fibers and the amount of pseudourea which is present in the fibers of the final product can be determined by calculation based on Kjeldahl nitrogen analysis.
Thereafter the suspension is processed into paper or paperboard in any customary manner. The fibers are formed into a web web by flowing the suspension over a foraminous substrate, and the web is dried at an elevated temperature into the desired form.
For the manufacture of cotton wool the fibers in the suspension may be allowed to accumulate on the foraminous substrate so as to form a wet web of substantial thickness which may be dried, and the resulting batt carded so as to separate the fibers into a fluffy wool-like product.
For processing into paper, the suspension is formed into a wet web at some normal basis weight and the wet web is dried over steam-heated rolls.
In many instances when the end product is paper or paperboard, it is desired that such product possess wet strength properties. These properties can be imparted by adding any of the known cationic thermosetting wet strength resins for paper along with the pseudourea, or by applying the wet strength resin subsequently, for exampleat the size press, the paper being subsequently the present invention possess superior dry strength without possessing permanent wet strength (to facilitate disposal of the paper after use). This can be accomplished by adding a water-soluble cationic or non-ionic dry strengthening agent along with pseudourea. Suitable polymers for this purpose are disclosed in Woodberry, U.S. Pat. Nos. 2,959,514 and 3,258,393.
The invention will be further illustrated by the following examples which illustrate embodiments of the invention and are not to be construed as limitations thereon.
EXAMPLE 1 The following illustrates the manufacture of antimicrobial cellulose fibers resulting from the presence thereon of a small amount of water-insoluble pseudourea.
Aliquots are taken from an aqueous neutral suspension of well-beaten cellulose papermaking fibers at a consistency 0.6 percent and to these are respectively added sufficient of 10 percent by weight solutions of:
l n-Decylpseudourea hydrochloride 2. n-Dodecylpseudourea nitrate .3. n-Dodecyl-N,N-dimethylpseudourea acetate 4. n-Hexadecylpseudourea trichloroacetate to provide up to 0.5 'percent of the urea derivative (as the free base), based on the dry weight of the fibers. The pH of the aliquots is then adjusted to 6, and the suspensions are gently stirred for a minute to permit the pseudourea to be adsorbed by the fibers. The pH of the suspension simultaneously decreases.
The resulting suspensions are formed into thick water-laid webs on a laboratory handsheet machine which are oven-dried at 190 F and the resulting webs are hand-carded using a textile carder. Fluffy resilient masses are obtained which resemble surgical cotton wool. I
Samples of the cotton wool are respectively sprayed with suspensions of: g
. Aerobacter aerogenes Bacillus cereals var. mycoides Pseudamonas aefuginosa Chaetamium globosum i Penicillium citrinum Penicillium expdnsum Trichoderma viride Aspergillusflavus Fusarium moniliforme l0. Aspergillus niger in a standard laboratory nutrient medium (agar-agar medium containing protein as source of nitrogen, carbohydrate, and calcium, magnesium, potassium and iron salts of the type normally present in said medium) to provide nutritional requirements for the microbial life thereon. The samples are allowed to stand for three days at 30 C. and 75 percent relative humidity, to permit the fibers to exert their biocidal properties, and then are incubated on sterile agar plates, in comparison with control samples of cotton wool which contain no antimicrobial agent, to determine the extent to which the microbial life has been arrested. At the end of the incubation period the plates carrying the test cotton wool are substantially or completely free from microorganisms, whereas the control plates carry heavy growths of microorganisms.
seepage-m EXAMPLE 2 The following illustrates the manufacture and use of mulch paper according to the present invention.
Into a furnish composed of a50z50 mixture of hard wood and soft wood papermaking fibers at pH 4.5 at a consistency of 0.6 percent, as it passes through the machine chest in a paper mill, is metered a 5 percent by weight solution of n-dodecylpseudourea hydrochloride at a sufficient rate to provide 0.5 1 percent of ndodecylpseudourea (as the free base) based on the dry .weight of the fibers and a solution of the melamine-formaldehyde wet strength acid colloid of Maxwell et al. U.S. Pat. No. 2,345,543 at the same rate. The furnish is processed into paper at a basis weight of 50 lbs. per 25" X 40"/500 ream, and the paper is dried at 190 F.-250 F. for about 1 minute. Kjeldahl nitrogen analyses of the paper show that the dry paper contains 60 percent percent by weight of the dodecylpseudourea which had been added. From experience it is known that most of the remainder was adsorbed by the cellulose fibers, which were lost with the white water.
The resulting paper is transported to a pineapple plantation, and is rolled upon the ground by an automatic pineapple seedling planter. Pineapple seedlings are then planted through approximately 1 inch diameter holes punched through the paper.
The paper largely prevents the growth of weeds around the seedlings, does not support microbiological growth during the period that the pineapples are growing, resists tearing when wet, and shortens the vegetation period of the pineapples. The paper loses virtually all its strength and disintegrates to fibrous state within three months after being ploughed under the ground.
EXAMPLE 3 The procedure of Example 2 is repeated except that the paper is applied as a mulch for watermelons, cauliflower, cabbage, celery, parsnips and tomatoes grown in a Florida soil. Similar results are obtained.
EXAMPLE 4 The following illustrates the remarkable antimicrobial properties possessed by a preferred paper of the present invention.
A sample of the paper of Example 2 is pressed upon a sterile Petri dish of agar upon which has previously rhesus monkey kidney cultures. A control is prepared consisting of 0.5 ml. of the virus in. 4.5 ml. of Earls lactalbumin hydrolysate medium.
The virucidal effectiveness of the solution is determined by the hemadsorption test wherein 3 days after inoculation the cell culture tubes are washed twice with 1.0 ml. of phosphate-buffered saline solution and 1 ml. of 0.4 percent guinea pig erythrocytes is added to each tube. The tubes are incubated for 20 minutes at 4" C. and washed again with 1.0 ml. of the saline solution. The erythrocytes adsorbed the monkey kidney cells that are infected with influenza.
The procedure is repeated except that 2-n-dodecyl- N,N-dimethyl pseudourea dihydro'gen phosphate is used in place of the acetate.
The virus potency (log TCID /ml.) is 5.2 for the control and 2.2 for each of the tests with the pseudou rea salts, where TCID represents Tissue Culture lnfection Dose.
Each of the pseudourea salts is toxic to the virus concentrations at 10'.
Control 1 Percent virus Test number Virus nsvd DPA P DDPITP 3 Test method used DPA 1 DDPHP 3 A Influenza ll 5.2 22 22 llemadsorption 100 100 13.. Adeuovirus type 3. 5. t 4. 7 4. 7 Viral eytopathologv... 80 80 C. Parainfluenza 3 4.2 22 22 d0 5 99.2 99, 2 1). Influenza A l5. 0 2. 2 2. 2 Hornadsorption 100 100 E.. Herpes simplex Vlt 2150 6.9 3. 2 3. 2 Viral cytopathology L 99. 2 99. 2 F U Para inlluenzali 5.7 2.2 llernadsorption 100 1 Log TCID/ /ml. (TCIl)=tissue culture infection (lOSl).
1 2-(n-d0decyl) pseudourea acetate.
3 2-(n-dodecyl)-l,1dimethyl-psoud0nrea dihydrogvn phosphate. 4 In this test the concentration of the dodecylpseudourea is 50 p,p.n1.
5 And hemadsorption.
been sprinkled an aqueous suspension of Aspergillus niger and other fungal spores. The dish is incubated at C. along with a control dish which contains no paper. After 48 hours the control dish carries a heavy growth of fungi, but the paper in the test dish shows no growth whatever. I
EXAMPLE 5 EXAMPLE 6 The following illustrates the virustatic and virucidal efficiency of the pseudoureas against typical lipophilic viruses.
Virus Used: Influenza B (National lnstitute of Health s Massachusetts Strain RMK-3) 80 mg. of 2-n-dodecylpseudourea acetate is dissolved in 200 ml. of warm distilled water giving a solution containing 400 ppm. of the agent. To 4.5 ml. of this solution is added 0.5 of the virus and shaken to form a uniform solution. The solution is maintained at 22C. 'for 10 minutes. Several dilutions are made to below 10 biocide concentration and inoculated into Example 7 The following illustrates the manufactureofan infants diaper according to the present invention.
To an aqueous suspension of cellulose papermaking fibers at pH 4.5 and a consistency of 0.6 percent is added sufficient of an aqueous solution of n (2- decyl)pseudourea acetate to provide 2 percent based on the dry weight of the fibers. The fibers are formed into a web on a screen and the web is allowed to air dry. The web is carded to form cotton wool whichv is formed into a batt about 18 inches X 18 inches X Vi inch. The batt is placed between two sheets of wet strength paper 18 inches l8 inches, one of. which is sized and the other is unsized. The edges of the two sheets are bound together with pressure-sensive adhesive tape.
Example 8 The following illustrates the antimicrobial effect of increasing amounts of a preferred antimicrobial agent as afunction of the kinds of microbial life present.
A water-leaf paper sheet (paper containing no additive) of 40 lb. basis weight per 25" X 40"/500 ream is immersed in a 0.05 percent by weight solution of 2-ndodecyl pseudourea (PU) and removed. Surplus solution is allowed to drain off. The resulting wet web is dried for one minute on a laboratory drum drier having a drum temperature of 240 F. and contains about 0.05 percent of the pseudourea by weight. The procedure is successively repeated with solutions of increasing strength, yielding papers of the psedudourea content shown in the table below.
The papers are then tested for their antimicrobial power against fungus (Aspergillus niger), and on a bacterium (Aerobacter aerogenes).
Results are as follows.
Growth After 48 PU Hours at 80F. No. In Paper Fungus Bacterium Control None Heavy Heavy l 0.05 Mod. Mod. 2 0.1 Do. Slight 3 0.2 Little Little 4 0.3 None None 5 0.5 Do. None 6 1.0 Do. Do.
Since 2-dodecylpseudourea is known to be a virucide, and since the above results show that this compound is adsorbed on paper in strongly biologically active form, it is expected that the paper described possesses strong antiviral properties as well.
Example 9 The following illustrates the manufacture of highly antimicrobial paper of excellent wet strength properties according to the invention.
To an aqueous suspension of unbleached softwood kraft fibers at 0.6 percent consistency and pH 6 in ordinary (non-aseptic) laboratory water is added with gentle stirring sufficient of a 5 percent by weight solution of 2-n-dodecylpseudourea hydrochloride to supply 3/4 percent of this compound based of the dry weight of the fibers. There is then added sufficient of a 1 percent solution of a water-soluble cationic thermosetting glyoxylated 95:5 molar ratio acrylamidezdiallyl dimethyl ammonium chloride copolymer to supply 1 percent of the polymer based of the dry weight of the fibers.
The suspension is then formed into handsheets at 50 lb. basis weight which are dried for one minute on a drying roll having a surface temperature of 220F.
The resulting paper carries about 0.6 percent and 0.8
percent by weight of the respective agents, and has a TAPPl wet tensile of 9 lb. per inch.
A 6" X 6" sheet of the paper is then inoculated with stock laboratory cultures so as to place on the sheet cultures of a bacterium and a fungus, and the sheet is allowed to airdry at 80F. for 30 minutes. The sheet is then rolled in a plastic sheet and allowed to incubate in the dark for 48 hours. The sheet is then incubated and is found to be sterile.
Example l0 An experimental childs diaper (a commercial cloth diaper having pinned to the center a pillow" composed of a batt of cellulose papermaking fibers between two sheets of wet strength paper, the fibers in the batt and the paper containing 1 percent of n-n-dodecylpseudourea by weight) is placed about a baby in approximately customary manner and left in position until soiled. The soiled pillow is removed and a sample incubated at F. No microbial growth develops.
1. Cellulose fibers having a uniformly adsorbed effective content within the range of 0.01 percent -3 percent based on the dry weight of the fibers as agent inhibiting the growth of microorganisms thereon of a 2- (Cg-C1 substantially straight chain alkyl) pseudourea.
2. Fibers according to claim 1 wherein the pseudourea is 2-n-dodecylpseudourea.
3. Antimicrobial paper consisting essentially of fibers according to claim 1.
4. lnfants diapers consisting essentially of a substantially square assembly of a batt of fibers according to claim 1 and two sheets of wet strength paper, one of which is sized and the other is unsized, said batt being positioned between said sheets of paper.
5. A process for the manufacture of antimicrobial paper which comprises forming an aqueous suspension of cellulose papermaking fibers, adding thereto a small but effective amount as antimicrobial agent of a salt of a 2-(C C substantially straight chain alkyl) pseudourea, forming said fibers into a wet web, and drying said web at a temperature between about F. to form paper.
6. A process according to claim 5 for the manufacture of paper which comprises forming an aqueous suspension of cellulose papermaking fibers, adding thereto sufficient of an acid solution ofa 2-(C C substantially straight chain alkyl polypseudourea) to deposit on said fibers an effective amount thereof within the range of 0.01 percent 3 percent based on the dry weight of said fibers as antimicrobial agent, adding to said suspension 0.1 percent 3 percent of a water-soluble cationic wet strength resin, forming said fibers into a web, and drying said web at a temperature between about 190 F. and 250 F.
7. A process according to claim 6 wherein the wet strength resin is a thermosetting resin containing amine-reactive substituents.
- UNITED STATES PATENT OFFICE QEE'EEMCATE OF CORRECTION Patent No. 5 7 5 Dated April 7, 97
Inventbflsg CHARLES mum HI m It is certified that error appears in the above-identified patent and that said Letters Patent arehereby corrected as shown below:
Column 1, line 2, !-2,7 +9" should read 423%??? Column 5, line 15, "web web" should read wet web Column L line 16, "i Penicillium oitrinum should read Penioillium citrinum colum 4 line 49, 0.5 1 percent" should read 0.5 percent Column 7 line 52, f the dry weight" should read on the dry weight Columhf 8 line 51 190F. to form" shouldread 190F. and 250F. to form Signed and sealed this 18th day of December 1973.
EDWARD l LFLETCI-IERJR. RENE D TEGTMEYER a A ttescing Officer Acting Commissioner of Patents FORM Po-wso (10-69) USCOMM-DC 00376-5 60 9 \LS. GOVIINIINT PIIIUING OFFICE I"! 0--36rlll
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2923656 *||Sep 18, 1953||Feb 2, 1960||Shell Dev||Acyl thiourea fungicidal and bactericidal compositions and method of protecting plants with the same|
|US2980734 *||Mar 10, 1959||Apr 18, 1961||Monsanto Chemicals||Thiopseudourea derivatives|
|US3060079 *||Aug 5, 1960||Oct 23, 1962||Electro Chem Fiber Seal Corp||Germicidal paper and method|
|US3483296 *||Mar 22, 1966||Dec 9, 1969||Ciba Ltd||Method of combatting microorganisms with benzylthioureas|
|CA618089A *||Apr 11, 1961||Du Pont||Paper treatment|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US4615937 *||Sep 5, 1985||Oct 7, 1986||The James River Corporation||Antimicrobially active, non-woven web used in a wet wiper|
|US4692374 *||Jul 16, 1986||Sep 8, 1987||James River Corporation||Antimicrobially active, non-woven web used in a wet wiper|
|US4732797 *||Feb 27, 1987||Mar 22, 1988||James River Corporation||Wet wiper natural acid preservation system|
|US4737405 *||Oct 31, 1986||Apr 12, 1988||James River Corporation||Binder catalyst for an antimicrobially active, non-woven web|
|US4740398 *||Sep 30, 1985||Apr 26, 1988||James River Corporation||Binder catalyst for an antimicrobially active, non-woven web|
|US4781974 *||Mar 9, 1987||Nov 1, 1988||James River Corporation||Antimicrobially active wet wiper|
|US4929498 *||Jan 31, 1989||May 29, 1990||James River Corporation Of Virginia||Engineered-pulp wet wiper fabric|
|US4948585 *||May 26, 1989||Aug 14, 1990||Schlein Allen P||Washcloth containing cleansing agent|
|US5191734 *||Apr 24, 1990||Mar 9, 1993||Kimberly-Clark Corporation||Biodegradable latex web material|
|US5242052 *||Jan 27, 1992||Sep 7, 1993||Highland Supply Corporation||Antimicrobial material and methods|
|US5558873 *||Mar 8, 1995||Sep 24, 1996||Kimberly-Clark Corporation||Soft tissue containing glycerin and quaternary ammonium compounds|
|US5652049 *||Dec 5, 1995||Jul 29, 1997||Paragon Trade Brands, Inc.||Antibacterial composite non-woven fabric|
|US5666784 *||May 23, 1995||Sep 16, 1997||Southpac Trust International, Inc.||Floral wrapper utilizing a breathable packaging material|
|US5743398 *||Oct 19, 1994||Apr 28, 1998||Southpac Trust International, Inc.||Floral wrapper utilizing a breathable packaging material|
|US5755320 *||May 23, 1995||May 26, 1998||Southpac Trust International, Inc.||Floral wrapper utilizing a breathable packaging material|
|US5783502 *||Jun 7, 1995||Jul 21, 1998||Bsi Corporation||Virus inactivating coatings|
|US5921062 *||Apr 1, 1998||Jul 13, 1999||Southpac Trust International, Inc.||Method of using a floral wrapper utilizing a breathable packaging material|
|US6382418||Jun 26, 2000||May 7, 2002||Southpac Trust International, Inc.||Floral wrapper utilizing a breathable packaging material|
|US7213366 *||Jun 23, 1999||May 8, 2007||Bentle Products Ag||Mixture of a carrier and additives for use in germinating units containing seeds or similar growth-suited parts of a plants as well as a method of producing the mixture|
|US7749525||Jul 6, 2010||The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center||Pest-impervious packaging material and pest-control composition|
|US8545906||May 31, 2010||Oct 1, 2013||The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center)||Pest-impervious packaging material and pest-control composition|
|US8802132 *||Jan 18, 2011||Aug 12, 2014||Cascades Canada Ulc||Anti-microbial tissue paper and process to manufacture same|
|US20030108761 *||Sep 12, 2002||Jun 12, 2003||Tammy Eddlemon||Anti-bacterial paper products|
|US20040038605 *||Dec 13, 2002||Feb 26, 2004||Hooper Douglas L.||Material and process for self-regulating temperature, wickability, flame- , biological-agent-, and soil-resistant controlled yarn, substrate or fabric|
|US20040083556 *||May 29, 2001||May 6, 2004||Masahiko Kurauchi||Fiber product having antibacterial and deodorant function|
|US20060105657 *||Nov 12, 2004||May 18, 2006||Cline Harry B||Microbial resistant kraft facing for fiberglass insulation|
|US20100236971 *||May 31, 2010||Sep 23, 2010||The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research||Pest-impervious packaging material and pest-control composition|
|US20120301536 *||Jan 18, 2011||Nov 29, 2012||Cascades Canada Ulc||Anti-microbial tissue paper and process to manufacture same|
|US20130197461 *||Mar 13, 2013||Aug 1, 2013||Gp Cellulose Gmbh||Modified cellulose from chemical kraft fiber and methods of making and using the same|
|EP0387586A1 *||Feb 26, 1990||Sep 19, 1990||Sakai Engineering Co., Ltd.||Antimicrobial/antibromic processing preparations|
|EP1291460A1 *||May 29, 2001||Mar 12, 2003||Ajinomoto Co., Inc.||Fiber product having antibacterial and deodorant function|
|EP1576882A1||Mar 31, 2004||Sep 21, 2005||Biopack Ltd||Pest-impervoius packaging material and pest-control composition|
|U.S. Classification||162/161, 424/443, 47/9, 162/158, 424/447, 514/588, 424/404|
|International Classification||A61L15/16, A61L15/20, D21H21/36, D21H21/14|
|Cooperative Classification||A61L15/20, D21H21/36|
|European Classification||A61L15/20, D21H21/36|