|Publication number||US3737579 A|
|Publication date||Jun 5, 1973|
|Filing date||Apr 19, 1971|
|Priority date||Apr 19, 1971|
|Also published as||CA994869A1, DE2219044A1, DE2219044B2, DE2219044C3, DE7214841U|
|Publication number||US 3737579 A, US 3737579A, US-A-3737579, US3737579 A, US3737579A|
|Original Assignee||Medtronic Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (3), Referenced by (99), Classifications (8)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Paten Bolduc 1 June 5,1973
Appl. No.: 135,277
US. Cl. ..12s/41s,-12s/419 P- lnt; Cl. ..A6ln 1/04 Field of Search ..l28/404, 4l 8, 419 P References Cited UNITED STATES PATENTS 12/1968 Quinn ..128/418 9/1971 Bolduc ..12s/41s 10/1969 Tachick ..l28l4l8 Primary Examiner-William E. Kamm Attorney-Irving S. Rappaport, Donald R. Stone and Lew Schwartz [5 7 ABSTRACT A body implantable electrode comprising a flexible insulated conductor having a proximal end adapted for connection to a power supply and a distal end portion comprising an uninsulated, conductive, rigid helix adaptedfor attachment to body tissue. Means located and engageable at substantially the distal end portion are provided for facilitating the screwing of the helix into body tissue. A device is provided with means for firmly holding the means for facilitating the screwing of the helix into bodyv tissue. The device also has means for holding the conductor and for preventing the transmission of torque to the proximal end of the conductor when the helix is being screwed into body tissue.
10 Claims, 4 Drawing Figures PAT'ENTEDJUN 5197s FIG.3
INVENTOR. LEE R. BOLDUC BY I ATTORNEY.
BODY TISSUE ELECTRODE AND DEVICE FOR SCREWING THE ELECTRODE INTO BODY TISSUE BACKGROUND OF THE INVENTION Electrical stimulation of body tissue and organs as a method of treating various pathological conditions is becoming quite common-place. Such stimulation generally entails making some type of electrical contact with the body tissue or organ. In particular, with respect to the heart, electrical leads have been developed in which an electrode formed on the end of the lead are physically implanted into the myocardial tissues. Various electrode structures and various techniques for implanting those structures into the myocardium have been developed. One such technique required a plurality of stab wounds to be made in the myocardium both for the location of the electrode as well as the suturing of the lead to myocardial tissue. Obviously, such wounds are undesirable for a variety of reasons. Other techniques have included the percutaneous insertion through the chest wall or an open wound by means of a hollow needle with the subsequent placement of the electrode into the myocardial tissue. Still another technique involved the deformation or flattening of one convolution of a rigid helix serving as the electrode so that a keyed stylet could engage the deformed convolution to permit the electrode to be screwed into the myocardial tissue. However, this technique requires that the stylet be in physical contact with the helix during insertion into the myocardium and in addition has the undesirable effect of imparting torque to the proximal end of the coiled conductor.
SUMMARY OF INVENTION In the present invention a body implantable electrode assembly is provided in which a flexible insulated electrical conductor has a proximal end thereof adaptable for connection to a power supply and a rigid helix serving as the distal end portion thereof. The rigid helix serves as the electrode to be screwed into the body tissue. This procedure is facilitated by a tool or member which is substantially cylindrically-shaped and having a slot located in one end surface thereof, the slot being substantially orthogonal to the longitudinal axis of the member. A groove is located in the outer surface of the member and extends from the end surface opposite the slotted end surface to just short of the slotted end surface and lies in a plane substantially parallel to the longitudinal axis. Also, starting in the same end surface as the groove is a bore extending for the entire length of the member for receiving the proximal end of the conductor.
The assembly is used during the implantation of the electrode into body tissue. A raised portion on the conductor near the distal end thereof is fitted into the slotted end of the cylindrically-shaped member. The insulated portion of the conductor is fitted into the groove and the remaining proximal portion of the conductor is inserted into the bore, connector end first. In this position the electrode comprising the rigid helix is securely held by the tool and by applying a twisting or rotation of the tool, the helical electrode may be screwed into the tissue, which in the case of the heart is the myocardium. When the electrode is securely screwed into the tissue, the portion of the conductor lying in the groove is removed and then the slotted end of thern'embe r is removed from the raised portion of the conductor.
The present invention has a number of advantages and features which include: (1') the tool used in facilitating the screwing-in of the electrode into the tissue or organ never contacts the electrode; (2) the configuration of the cylindrically-shaped member and the positioning of the conductor with respect thereto prevents any torque from being imparted to the conductor along its entire length during the rotation of the member; (3) the electrode assembly permits the use of wrapped on tinsel wire, rather than a coiled wire, which has great strength and a very good flex tolerance; (4) the electrode is extremely easy to install, reduces patient trauma, effects a very sound electrical connection description taken in connection with the accompanying drawings.
DESCRIPTION OF DRAWINGS FIG. 1 shows a diagram of an implantable lead in accordance with the present invention;
FIG. 2 illustrates an embodiment of the device used in conjunction with the lead of FIG. 1 for screwing the electrode into body tissue;
FIG. 3 is a cross-sectional view of the device shown in FIG. 2; and
FIG. 4 illustrates the lead of FIG. 1 and the device of FIGS. 2 and 3 in operative relationship for the insertion of the electrode into body tissue.
DESCRIPTION OF THE PREFERRED EMBODIMENT FIG. 1 shows an implantable lead 10 which includes a flexible electrical conductor 12. Conductor 12 may, for example, be made of wrapped platinum wire or other suitable conducting material adaptable to the intemal environment of a human or animal body. Wrapped platinum wire is generally comprised of a pluv rality of platinum ribbons each helically wound around a separate electrically non-conductive core and then all the platinum ribbons are helically wound around a central electrically non-conductive core. A specific description of this type of conductor may be found in my US. Pat. No. 3,572,344, issued Mar. 23, 197i, and entitled Electrode Apparatus With Novel Lead Construction." Affixed to the proximal end of conductor 12 is an electrical connector 14 having a tip orextension 16 which may be connected to a suitable implantable or external power supply. Affixed to and serving as the distal end portion of conductor 12 is a rigid helical electrode 18 having several convolutions. Helical electrode 18 is a rigid coil which may, for example, be made of platinum irridium, and terminates in a sharply pointed end 19. Electrode 18 serves as the distal end portion of conductor 12 which may be screwed into body tissue as will be explained later. Electrode l8 and of projection 24 are three spaced, substantially vertical ribs 25 which are adapted to permit projection 24 to be more securely engaged as will be explained. The distal portion of casing 22 is terminated and shaped as a circular disc 26 through which helical electrode 18 projects. Helical electrode 18 projects through disc 26 at substantially a right angle to conductor 12. Affixed to the under surface of disc 26 is a circular sheet of netting 28, which may, for example, be made of Dacron which is a trademark of E. I. Du Pont De Nemours and Company for a type of polyester fiber. Netting 28 enhances fibroticgrowth, further insuring a secure connection of the electrode to the tissue.
FIGS. 2 and 3 illustrate the device used in conjunction with lead to facilitate the screwing of electrode 18 into body tissue. Device 40 comprises a substantially cylindrically-shaped member or tool having a longitudi- I nal axis 42 and end surfaces 44 and 46. Member 40 may be made, for example, of a hard plastic material such as Delrin which is a trademark of the E. I. Du Pont De Nemours and Company for acetal resins. Preferably member 40 should be made of a autoclavable material. Formed in end surface 44 is a slot 48. Slot 48 is shaped so as to be adapted to substantially conform to and securely-engage ribs 25 of raised portion 24 of lead 10. The edge defined by end surface 46 is rounded in order to permit member 40 to be used for surgically producing a tunnel in subcutaneous tissue without causing severe tissue damage. Formed in the outer surface of member 40, lying in a plane substantially parallel to axis 42, and extending from end surface 46 for substantially the entire length of member 40 is a groove 50. Groove 40 is substantially aligned with slot 48. Groove 50 is adaptable to receive and securely engage at least a portionof the length of the insulated portion of lead 10 housed in casing 22. Also formed in end surface 46 is an axial opening or bore 52 extending the entire length of member 40 from end surface 46 to slot 48. Bore 52 is adapted to receive at least a portion of the proximal end of lead 10 including connector 14 and tip 16.
FIG. 4 illustrates the operative relationship between lead 10 and member 40 as will now be described. Raised portion 24 is first inserted into slot 48 so that the surfaces defining slot 48 firmly grip ribs 25 to pro vide a friction fit and securely hold projection 24 in the slot. A small loop is left in the portion of casing 22 im- Pointed end 19 is placed against the tissue or organ and member 40 is rotated as indicated by the curved arrow-The diameter of the wound is confined to the diameter of the wire of which helical electrode 18 is formed. As member 40 is rotated, helical electrode 18 is firmly screwed into the tissue or organ until netting 2'8 firmly contacts the outer-surface of the organ. Netting 28 helps to provide a more secure and permanent placement of electrode 18 in the tissues in that the netting promotes more rapid fibrosis in andaround the netting, as well as around disc 26 and raised portion 24 of casing 22.
When electrode 18 is firmly screwed into the tissue and netting 28 firmly seated against theouter surface of the tissue or organ, the connector-end of lead '10 is removed from bore 52, the portion of casing 22 lying in groove 50 is removed from the groove,and then slot 48 is disengaged from projection 24 thereby freeing lead 10 from member 40. With the use of the procedure described, since projection 24 and a substantial portion of casing 22 are firmly secured during the rotation of member 40, no torque is transmitted to lead 10 and consequently to conductor 12. In addition, before, during, and after the insertion procedure, member 40 in no way contacts the helical convolutions of electrode 18, permitting a very positive action in screwing electrode 18 into the tissue at substantially a angle. Then, if desired, end surface 46 of member 40 may be used to provide a tunnel in the subcutaneous layers. The connector-end oflead 10 may then be inserted into bore 52 and member 40 guided back through the tunnel in order to facilitate connecting tip 16 of conductor 14 to a power supplyv to be implanted under the skin.
Obviously, many modifications and variationsof the present invention are possible in the light of the above teachings even though only one embodiment of the invention has been shown. For example, the presence and use of bore 52 are entirely optional and do not affect the screwing of the electrode into body tissue. Also, the exact shape and size of the projection 24 and the matching slot 48, as well as the shape, size and extent of groove 50, are all subject to modification within the scope of the present invention. It is therefore to be understood, that within the scope of the appended claims, the invention may be practiced otherwise than as specifically described.
What is claimed is:
I. In a body implantable electrode assembly that includes a flexible electrical conductor means having a proximal end thereof adaptable for connection to a power supply and wherein the distal end portion of the conductor comprises an uninsulated, conductive, rigid helix adapted for attachment to body tissue, the improvement which comprises:
means located and engageable at substantially said distal end portion for facilitating the screwing of said helix into body tissue and for preventing the transmission of torque to said proximal end of said conductor means when said helix is being screwed into body tissue, said means including further friction increasing means adapted to be firmly held by means used for screwing said helix into body tissue, said means and said further means being substantially inert to body fluids and tissue; and
means substantially inert to body fluids and tissue enclosing substantially the entire length of said conductor means except for said distal endportion for permitting said electrode assembly to be implanted within the body.
2. The invention as set forth in claim 1 wherein:
said means located and engageable at the distal end portion comprises a raised section of insulation surrounding the conductor, and wherein;
said further means comprises at least one rib on the outer surface of said raised section adapted to frictionally fit with a member having a slot defined therein for receiving said raised section and said at least one rib.
3. The invention as set forth in claim 1 wherein:
said conductor comprises a plurality of electrically non-conducting cores, a plurality of conductive metal ribbons, each of said ribbons being helically wound around a separate one of said electrically non-conducting cores, and a central electrically non-conducting core, said plurality of ribbons wound on said cores being helically wound around said central core.
4. The invention as set forth in claim 3 wherein:
said ribbons are made of platinum. 5. A device for use in screwing the conductive uninsulated distal end portion of a body implantable electrode assembly into body tissue, said assembly being of the type including a flexible insulated electrical conductor having a proximal end thereof adaptable for connection to a power supply, said device comprising:
first means for firmly holding a portion of said electrode assembly near said uninsulated distal end portion thereof, said first means contacting only an insulated portion of said electrical conductor; and
second means adapted to contact an insulated portion of said insulated conductor for holding said conductor to facilitate the screwing of said distal end portion into body tissue and for preventing the transmission of torque to said proximal end of said conductor means when said distal end portion is being screwed into body tissue.
6. A device for use in screwing the conductive, uninsulated distal end portion of a body implantable electrode assembly into body tissue, said assembly being of the type including a flexible insulated electrical conductor having a proximal end thereof adaptable for connection to a power supply, said device comprising:
a substantially cylindrically-shaped member having a pair of end surfaces;
one end surface of said member having a slot defined therein for engagement with a portion of said electrode assembly located proximally with respect to said distal end portion thereof; and the outer surface of said member having a groove formed therein, said groove lying substantially parallel to the longitudinal axis of said member, said groove being engageable with a portion of said insulated conductor, whereby rotation of said member about said longitudinal axis permits said distal end portion to be screwed into body tissue without said member contacting said distal end portion and without imparting any torque to said conductor along its length.
7. The device as set forth in claim 6 wherein:
said member has an axially-extending opening extending from said one end surface to said other end surface.
8. The device as set forth in claim 6 wherein:
said groove extends from said other end surface toward said one end surface.
9. The combination of a body implantable electrode assembly including a flexible insulated electrical conductor means having a proximal end thereof adaptable for connection to a power supply and a conductive uninsulated distal end portion and a device for use in screwing the conductive, uninsulated distal end portion of said assembly into body tissue, said combination comprising:
an electrical conductor having its uninsulated distal end portion formed as a rigid helix;
slot engageable means surrounding said conductor proximally with respect to said distal end portion; first means defining a slot for rigidly engaging said slot engageable means; and second means formed integrally with said first means for rigidly engaging a portion of said insulated conductor, whereby rotation of said first and second means permits said distal end portion to be screwed into body tissue without said first and second means coming into contact with said distal end portion and without imparting any torque to said conductor along its length. 10. The combination as set forth in claim 9 wherein: said device for screwing comprises a substantially cylindrically-shaped member having an axiallyextending bore, said bore extending from said one end surface to said other end surface of said member, said bore being adapted to receive the proximal end of said conductor;
said first means comprises one end surface of said member having said slot formed therein; and
said second means comprises the outer surface of said member having a groove formed therein, said groove lying substantially parallel to the longitudinal axis of said member and extending from the other end surface of said member toward said one end surface.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3416534 *||Apr 11, 1966||Dec 17, 1968||Gen Electric||Body organ electrode|
|US3472234 *||Aug 15, 1967||Oct 14, 1969||Gen Electric||Body organ electrode|
|US3572344 *||Dec 31, 1968||Mar 23, 1971||Medtronic Inc||Electrode apparatus with lead construction|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3875947 *||Feb 19, 1974||Apr 8, 1975||Jula James L||Device for screwing body tissue electrode into body tissue|
|US3910271 *||May 24, 1974||Oct 7, 1975||Theodore C Neward||Method of making a bipolar electrode structure|
|US3924639 *||Jul 17, 1974||Dec 9, 1975||Cordis Corp||Cardiac pacer lead system for interim pacing during pacer changeover|
|US3943936 *||Oct 9, 1973||Mar 16, 1976||Rasor Associates, Inc.||Self powered pacers and stimulators|
|US3964473 *||Sep 19, 1973||Jun 22, 1976||Telectronics Pty. Limited||Bone prosthesis|
|US4010757 *||Jan 24, 1975||Mar 8, 1977||Jula James L||Auxiliary tool for removing electrode from holder|
|US4010758 *||Sep 3, 1975||Mar 8, 1977||Medtronic, Inc.||Bipolar body tissue electrode|
|US4011861 *||Oct 28, 1975||Mar 15, 1977||Case Western Reserve University||Implantable electric terminal for organic tissue|
|US4026300 *||Mar 14, 1975||May 31, 1977||Liberty Mutual||Method and apparatus for interfacing to nerves|
|US4026301 *||Apr 21, 1975||May 31, 1977||Medtronic, Inc.||Apparatus and method for optimum electrode placement in the treatment of disease syndromes such as spinal curvature|
|US4030509 *||Sep 30, 1975||Jun 21, 1977||Mieczyslaw Mirowski||Implantable electrodes for accomplishing ventricular defibrillation and pacing and method of electrode implantation and utilization|
|US4031882 *||Jun 28, 1976||Jun 28, 1977||Liberty Mutual Insurance Company||Apparatus for interfacing to anatomic signal sources|
|US4046141 *||Jul 14, 1975||Sep 6, 1977||Liberty Mutual Insurance Company||Method and apparatus for interfacing to anatomic signal sources|
|US4058128 *||Aug 26, 1976||Nov 15, 1977||Frank Howard A||Electrode|
|US4066085 *||May 20, 1976||Jan 3, 1978||Cordis Corporation||Contact device for muscle stimulation|
|US4094321 *||Feb 7, 1977||Jun 13, 1978||Rudolph Muto||Shallow, dome-shaped pacer with bottom storage means for catheter|
|US4149542 *||Jan 28, 1977||Apr 17, 1979||Siemens Aktiengesellschaft||Endocardial electrode|
|US4207903 *||Apr 28, 1978||Jun 17, 1980||Medtronic, Inc.||Device for screwing body tissue electrode into body tissue|
|US4235246 *||Feb 5, 1979||Nov 25, 1980||Arco Medical Products Company||Epicardial heart lead and assembly and method for optimal fixation of same for cardiac pacing|
|US4270549 *||Apr 30, 1979||Jun 2, 1981||Mieczyslaw Mirowski||Method for implanting cardiac electrodes|
|US4271846 *||Apr 23, 1979||Jun 9, 1981||Daig Corporation||Lead installation tool|
|US4282885 *||Aug 21, 1978||Aug 11, 1981||Bisping Hans Juergen||Electrode for implantation in the heart|
|US4282886 *||Nov 13, 1979||Aug 11, 1981||Medtronic, Inc.||Adhesive bonded positive fixation epicardial lead|
|US4299239 *||Feb 5, 1979||Nov 10, 1981||Intermedics, Inc.||Epicardial heart lead assembly|
|US4323081 *||Jun 30, 1980||Apr 6, 1982||Medtronic, Inc.||Pacing lead|
|US4355642 *||Nov 14, 1980||Oct 26, 1982||Physio-Control Corporation||Multipolar electrode for body tissue|
|US4444206 *||Apr 29, 1982||Apr 24, 1984||Cordis Corporation||Mesh tip pacing lead assembly|
|US4644957 *||Apr 8, 1985||Feb 24, 1987||Ricciardelli Robert H||Applicator structure for biological needle probes employing spiral-shaped retaining coils|
|US4819661 *||Oct 26, 1987||Apr 11, 1989||Cardiac Pacemakers, Inc.||Positive fixation cardiac electrode with drug elution capabilities|
|US4865037 *||Nov 13, 1987||Sep 12, 1989||Thomas J. Fogarty||Method for implanting automatic implantable defibrillator|
|US4936306 *||Nov 27, 1985||Jun 26, 1990||Doty James R||Device and method for monitoring evoked potentials and electroencephalograms|
|US4972847 *||Nov 2, 1989||Nov 27, 1990||Dutcher Robert G||Pacing lead and introducer therefor|
|US5052392 *||Feb 14, 1990||Oct 1, 1991||Angeion Corporation||Cardiac sensing lead|
|US5143090 *||May 30, 1991||Sep 1, 1992||Possis Medical, Inc.||Cardiac lead|
|US5150709 *||Feb 11, 1991||Sep 29, 1992||Neward Theodore C||Spiral electrode with contact retainer|
|US5176137 *||Mar 1, 1991||Jan 5, 1993||Medtronic, Inc.||Apparatus for discrimination of stable and unstable ventricular tachycardia and for treatment thereof|
|US5193535 *||Aug 27, 1991||Mar 16, 1993||Medtronic, Inc.||Method and apparatus for discrimination of ventricular tachycardia from ventricular fibrillation and for treatment thereof|
|US5243980 *||Jun 30, 1992||Sep 14, 1993||Medtronic, Inc.||Method and apparatus for discrimination of ventricular and supraventricular tachycardia|
|US5246014 *||Nov 8, 1991||Sep 21, 1993||Medtronic, Inc.||Implantable lead system|
|US5257621 *||Jan 29, 1993||Nov 2, 1993||Medtronic, Inc.||Apparatus for detection of and discrimination between tachycardia and fibrillation and for treatment of both|
|US5342413 *||May 19, 1993||Aug 30, 1994||Siemens-Elema Ab||Medical electrode arrangement|
|US5344430 *||Apr 8, 1993||Sep 6, 1994||Medtronic, Inc.||Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation|
|US5383922 *||Mar 15, 1993||Jan 24, 1995||Medtronic, Inc.||RF lead fixation and implantable lead|
|US5531779 *||Jan 24, 1995||Jul 2, 1996||Cardiac Pacemakers, Inc.||Stent-type defibrillation electrode structures|
|US5851226 *||Oct 22, 1996||Dec 22, 1998||Medtronic, Inc.||Temporary transvenous endocardial lead|
|US5876430 *||Dec 17, 1997||Mar 2, 1999||Medtronic, Inc.||Method to stiffen and provide abrasion to connector end of leads|
|US5928276 *||Jun 11, 1998||Jul 27, 1999||Griffin, Iii; Joseph C.||Combined cable and electrophysiology catheters|
|US6010526 *||Sep 18, 1998||Jan 4, 2000||Medtronic, Inc.||Epicardial lead implant tool and method of use|
|US6718212||Oct 12, 2001||Apr 6, 2004||Medtronic, Inc.||Implantable medical electrical lead with light-activated adhesive fixation|
|US6745079||Nov 7, 2001||Jun 1, 2004||Medtronic, Inc.||Electrical tissue stimulation apparatus and method|
|US6876885||Jan 11, 2002||Apr 5, 2005||Medtronic, Inc.||Implantable bifurcated gastrointestinal lead with active fixation|
|US6952613||Jan 11, 2002||Oct 4, 2005||Medtronic, Inc.||Implantable gastrointestinal lead with active fixation|
|US7146225||Oct 30, 2002||Dec 5, 2006||Medtronic, Inc.||Methods and apparatus for accessing and stabilizing an area of the heart|
|US7251532||Oct 17, 2003||Jul 31, 2007||Medtronic, Inc.||Medical lead fixation|
|US7270669 *||Mar 5, 2003||Sep 18, 2007||Medtronic, Inc.||Epicardial lead placement for bi-ventricular pacing using thoracoscopic approach|
|US7418298||Oct 22, 2004||Aug 26, 2008||Cardiac Pacemakers, Inc.||Myocardial lead with fixation mechanism|
|US7437195||Jan 3, 2002||Oct 14, 2008||Metalure N.V.||Regulation of eating habits|
|US7499757||Oct 22, 2004||Mar 3, 2009||Cardiac Pacemakers, Inc.||Absorbable myocardial lead fixation system|
|US7499759||Oct 22, 2004||Mar 3, 2009||Cardiac Pacemakers, Inc.||Distal or proximal fixation of over-the-tether myocardial leads|
|US7502649||Jun 20, 2004||Mar 10, 2009||Metacure Ltd.||Gastrointestinal methods and apparatus for use in treating disorders|
|US7512442||Oct 28, 2005||Mar 31, 2009||Metacure N.V.||Acute and chronic electrical signal therapy for obesity|
|US7546164||Mar 19, 2004||Jun 9, 2009||Medtronic, Inc.||Electrical tissue stimulation apparatus and method|
|US7720550||Dec 3, 2004||May 18, 2010||Medtronic, Inc.||High impedance active fixation electrode of an electrical medical lead|
|US7840283||Sep 21, 2006||Nov 23, 2010||Pacesetter, Inc.||Bipolar screw-in lead|
|US7862573||Apr 21, 2006||Jan 4, 2011||Darois Roger E||Method and apparatus for surgical fastening|
|US8170692||Jan 29, 2010||May 1, 2012||Pacesetter, Inc.||Implant tool for active fixation lead|
|US8295932||Dec 5, 2006||Oct 23, 2012||Metacure Limited||Ingestible capsule for appetite regulation|
|US8301256||Jun 4, 2006||Oct 30, 2012||Metacure Limited||GI lead implantation|
|US8332051||May 18, 2010||Dec 11, 2012||Medtronic, Inc.||High impedance active fixation electrode of an electrical medical lead|
|US8346373||Aug 10, 2010||Jan 1, 2013||Medtronic, Inc.||Method and apparatus for delivering a lead to a heart|
|US8442841||Oct 20, 2006||May 14, 2013||Matacure N.V.||Patient selection method for assisting weight loss|
|US8449569||Dec 30, 2009||May 28, 2013||MiT Capital Partners, LLC||Apparatus for manipulation of implantable medical device and associated method|
|US8463404||Jan 14, 2007||Jun 11, 2013||Metacure Limited||Electrode assemblies, tools, and methods for gastric wall implantation|
|US8612016||Aug 18, 2005||Dec 17, 2013||Metacure Limited||Monitoring, analysis, and regulation of eating habits|
|US8666495||Mar 18, 2005||Mar 4, 2014||Metacure Limited||Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar|
|US8792985||Jan 20, 2006||Jul 29, 2014||Metacure Limited||Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar|
|US8868214||Jul 14, 2006||Oct 21, 2014||Cardiac Pacemakers, Inc.||Cardiac electrode anchoring system|
|US8934975||Feb 1, 2011||Jan 13, 2015||Metacure Limited||Gastrointestinal electrical therapy|
|US8979874||Dec 23, 2010||Mar 17, 2015||Davol, Inc.||Method and apparatus for surgical fastening|
|US9101765||Feb 16, 2006||Aug 11, 2015||Metacure Limited||Non-immediate effects of therapy|
|US20040088035 *||Oct 30, 2002||May 6, 2004||Medtronic, Inc.||Methods and apparatus for accessing and stabilizing an area of the heart|
|US20040186544 *||Mar 19, 2004||Sep 23, 2004||Medtronic, Inc.||Electrical tissue stimulation apparatus and method|
|US20050033396 *||Apr 9, 2004||Feb 10, 2005||Peter Ospyka||Cardiac electrode anchoring system|
|US20050085886 *||Oct 17, 2003||Apr 21, 2005||Medtronic, Inc.||Medical lead fixation|
|US20050113900 *||Oct 22, 2004||May 26, 2005||Cardiac Pacemakers, Inc.||Myocardial lead with fixation mechanism|
|US20050113901 *||Oct 22, 2004||May 26, 2005||Cardiac Pacemakers, Inc.||Myocardial lead attachment system|
|US20050119718 *||Oct 22, 2004||Jun 2, 2005||Cardiac Pacemakers, Inc.||Absorbable myocardial lead fixation system|
|US20050137672 *||Oct 22, 2004||Jun 23, 2005||Cardiac Pacemakers, Inc.||Myocardial lead|
|US20050137674 *||Oct 22, 2004||Jun 23, 2005||Cardiac Pacemakers, Inc.||Distal or proximal fixation of over-the-tether myocardial leads|
|USRE28990 *||Feb 6, 1975||Oct 5, 1976||Corometrics Medical Systems, Inc.||Bipolar electrode structure for monitoring fetal heartbeat and the like|
|DE2917173A1 *||Apr 27, 1979||Nov 8, 1979||Medtronic Inc||Vorrichtung zum anbringen einer elektrode an koerpergewebe|
|DE3523226A1 *||Jun 28, 1985||Jan 8, 1987||Osypka Peter||Defibrillations-elektrode|
|EP0591680A1 *||Sep 2, 1993||Apr 13, 1994||Pacesetter AB||Electrode system for pacemakers|
|WO1982002663A1 *||Feb 4, 1981||Aug 19, 1982||Mieczyslaw Mirowski||Method and apparatus for implanting cardiac electrodes|
|WO1992021405A1 *||May 29, 1992||Dec 10, 1992||Possis Medical Inc||Bipolar cardiac lead|
|WO1998017345A1||Oct 14, 1997||Apr 30, 1998||Medtronic Inc||Temporary transvenous endocardial lead|
|WO2004041349A1||Oct 27, 2003||May 21, 2004||Medtronic Inc||Methods and apparatus for accessing and stabilizing an area of the heart|
|WO2005037368A1 *||Oct 14, 2004||Apr 28, 2005||Hess Douglas N||Medical lead fixation|
|WO2009134960A2||Apr 30, 2009||Nov 5, 2009||Medtronic, Inc.||Extra-cardiac implantable device with fusion pacing capability|
|International Classification||A61N1/375, A61N1/05, A61N1/372|
|Cooperative Classification||A61N1/0587, A61N1/375|
|European Classification||A61N1/375, A61N1/05P|