|Publication number||US3767085 A|
|Publication date||Oct 23, 1973|
|Filing date||Aug 2, 1971|
|Priority date||Aug 2, 1971|
|Publication number||US 3767085 A, US 3767085A, US-A-3767085, US3767085 A, US3767085A|
|Inventors||J Cannon, R Kinsey|
|Original Assignee||J Cannon, R Kinsey|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (8), Referenced by (269), Classifications (26)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent 1 Cannon et al.
[ 1 Oct. 23, 1973 1 1 MIXING SYRINGE 21 Appl. No.: 168,056
 US. Cl 222/82, 222/137, 222/145,
222/327  Int. Cl B67b 7/28  Field of Search 222/82, 86, 88, 136,
Myers et a1... Melsen 3,311,265 311967 Creighton et a1. 222/137 FOREIGN PATENTS OR APPLICATIONS 896,993 5/1962 Great Britain lSIDIG. 1
1,126,082 3/1962 Germany 15/DIG. 1
Primary Examiner-Robert B. Reeves Assistant Examiner-Larry Martin Attorney-Newton, Hopkins & Ormsby  1 ABSTRACT A double barrel carpule type syringe having, at its discharge end, a common mixing and dispensing chamber provided with a rotary agitator driven from a motor on the syringe. One barrel of the carpule contains an elastomeric base material and the other an ac celerator, therefor. The syringe has a double plunger by means of which the base material and the accelerator are simultaneously discharged into the chamber in prescribed proportions as the mixed material is discharged from the end of the chamber. The mixing chamber assembly and the carpule assembly are readily removable from the body of the syringe.
1 Claim, 9 Drawing Figures MIXING SYRINGE SUMMARY OF THE INVENTION This invention relates to a dental mixing syringe, and is more particularly concerned with a device for mixing elastic impression material immediately prior to the material being discharged into the mouth of a patient for creating an impression of a tooth.
In the past, numerous elastic or elastomeric impression materials have been produced, each of these being a two component system containing an accelerator and a base. According to prior art practices the two components are mixed together in open air, on a pad, and then transferred to the syringe used to place the material in its proper position surrounding the prepared teeth. This method has many problems, some of them are (I) messy (2) time wasted (3) odor when using many materials (4) need for spatula and mixing pad (5) excess force needed to eject the material from the syringe, when using the syringe in placing the material around the last prepared teeth in a multiple tooth impression due to the material beginning to set up in the syringe. It is, therefore, common practice among dentists to utilize a dental technician or assistant to prepare the material and assist him so that the dentist can concentrate on the preparation of the mouth for receiving the impressionmaterial and to apply the material rapidly so as to minimize the problems as much as possible.
Briefly described, the present invention which obviates the difficulties described above is a multi-cylinder syringe having a removable, double barrel carpule. One cylinder or barrel of the carpule contains the base while the other contains the accelerator. The syringe has a pair of plungers which simultaneously discharge the liquid, i.e. base and accelerator, contained in the respective cylinders into one end of a common chamber where an agitator, driven by a motor, thoroughly mixes the same and provides for the discharge from the other end of the mixed material. The device is held as a conventional syringe, and the rate of depression of the plunger regulates the discharge of material.
The term carpule, as used herein, means a fluid container comprising one or more cylindrical barrels and adapted for insertion in a syringe.
Accordingly, it is an object of the present invention to provide a mixing syringe which is inexpensive to manufacture, durable in structure and efficient in operation.
Another object of the present invention is to provide a mixing syringe which will uniformly mix two fluids and provide for the discharge of the mixed fluids at a manually controlled rate therefrom.
Another object of the present invention is to provide a dental mixing syringe which will accurately measure and adequately mix the ingredients of an impression material, and thereafter dispense prescribed increments of the resulting mix.
Another object of the present invention is to provide a dental mixing syringe which will waste very little material and will save time and effort in enabling a dentist to mix the accelerator and base of impression material in a person's mouth immediately prior to dispensing the same.
Another object of the present invention is to provide a dental mixing syringe which will mix and dispense the material in small portions so that the consistency of the material is always the same no matter how many teeth are involved in the impression.
Another object of the present invention is to provide a method of mixing impression material which will confine the odor of the mixed material and which will provide a convenient and non-messy way of producing a thoroughly mixed impression material.
Another object of the present invention is to provide a dental mixing syringe in which the carpule therefore may be readily and easily inserted and in which the nozzle assembly therefore may be readily and easily changed, as desired.
Another object of the present invention is to provide a method of mixing a dental impression material which will obviate the necessity of a mixing pad and a spatula.
Another object of the present invention is to provide a disposable nozzle assembly for a dental mixing syringe, the disposable nozzle assembly being inexpensive to manufacture, efficient in operation and readily attached and removed from the syringe body.
Another object of the present invention is to provide a disposable multi-barrel carpule which may be readily and easily inserted into a syringe body for use, and readily and easily removed therefrom after use.
Another object of the present invention is to provide DESCRIPTION OF THE DRAWINGS FIG. 1 is an exploded perspective view of a dental mixing syringe constructed in accordance with the present invention;
FIG. 2 is an enlarged fragmentary perspective view of the mixing nozzle assembly of the syringe disclosed in FIG. 1;
FIG. 3 is a vertical sectional view of the syringe shown in FIG. I, the cover of the syringe body being open to disclose the double barrel carpule received therein;
FIG. 4 is a rear, partially broken away, vertical sectional view of the backside of the syringe illustrated in FIGS. 1 and 3;
FIG. 5 is an enlarged, vertical-sectional, fragmentary view showing the discharge nozzle portion of the mixing tube of the syringe shown in FIG. 1;
FIG. 6 is a cross-sectional view taken substantially along lines 66 in FIG. 3;
FIG. 7 is a schematic electrical diagram showing the one circuit arrangement for the motor of the syringe shown in FIG. 1;
FIG. 8 is a view similar to FIG. 7, showing a second embodiment of the electrical arrangement for the motor; and
FIG. 9 is a view similar to FIGS. 7 and 8 but showing still a third embodiment of the electrical circuitry forthe motor of the syringe, shown in FIG. 1.
DETAILED DESCRIPTION Referring now in detail to the embodiments chosen for the purpose of illustrating the present invention, numeral 10 denotes generally the metal body of the syringe which body includes a pair of opposed carpule receiving or housing members, i.e. a cradle 11 and a cover 12, hinged along a common edge by a piano hinge 13.
The base housing member or cradle 11 includes a pair of parallel, concaved, juxtaposed, semi-cylindrical grooves or inner surfaces 14 and 15 which merge along a central ridge 16, so as to provide a receiving cradle for the double barrel carpule, denoted generally by numeral 20.
The double barrel carpule 20 includes a pair of hollow, clear plastic, tubular barrels or cylinders 21 and 22 which are joined axially throughout their length by a rectangular petition plate 23. The petition plate 23 is disposed along the plane, common to the axes of the cylinders 21 and 22. At one end of the plate 23 is pro vided an ejector lever 24, projecting sidewise or normal to the plane of 23.
Preferably, the double barrel carpule 20 is cast as an integral or unitary member, the cylinders 21 and 22 being provided respectively with a pair of axial, cylindrical or uniform diameter bores 25 and 26, throughout their lengths.
As is common in carpules, liquid within the bores 25 and 26 are confined by rubber or resilient sliding plugs 27 and 28 and fixed plugs 29 and 30. As will be understood by those skilled in the art, liquid is discharged from the interior of'the bores 25 and 26 by puncturing the plugs 29 and 30, respectively, and by urging the sliding plugs 27 and 28 inwardly toward plugs 29 and 30.
The lever 24 is provided for the purpose of permitting the carpule 20 to be tilted out of the base member or cradle 11, when the syringe body is open. This lever 24 tapers outwardly and is provided with a rounded knob 31 at its distal end. It is disposed approximately parallel to the piston end of the double barrel carpule 20.
The hinged cover member 12 is pivotally carried by the cradle or base member 11 and is adapted to pivot about the piano hinge 13 from an open position, as seen in FIGS. 1 and 3, to a closed position, as illustrated in FIG. 4.
The outer edge 32 of the cover member 12 which is opposite the edge containing hinge 13 is provided with one element; namely, a latch 33 of a detent, the latch 33 having an inwardly projecting lug 34 which is received in an opening 35 in the outer side edge 36 of the cradle member 11, when the cover 12 is closed against the cradle member 11.
The inner surface of the cover member 12 is complementary to the inner surface of the cradle member 11, including a pair ofjuxtaposed semi-cylindrical surfaces 37 and 38 which are joined along a central ridge portion 39.
It will be understood that when the cover member-12 is closed against the cradle member 11, the surfaces 38 and 14 define a cylinder having a longitudinal axis and adapted to confine the cylinder 21. In like manner, the opposed concaved surfaces and 37 confine the cylinder 22. The opposed ridges l6 and 39 thus receive and clamp, therebetween, the plate 23. Hence, the double barrel carpule is confined by the cradle member 11 and the cover member 12 against a lateral movement, when the lug 34 is received in the aperture 35.
For confining the double barrel carpule 20 against longitudinal movement, with respect to the body 10,
the forward end portion of body 10 is provided with a nozzle member receiving cap, denoted generally by numeral 50. Furthermore, the rear end of body 10 is provided with a flat transversely extending handle or finger grip, denoted generally by numeral 60, the extremities of which protrude outwardly of member 11 and 12 to provide finger receiving wings 61 and 62. The wings 61, 62 extend in opposite directions outwardly in generally radial directions from the body 10, as seen best in FIG. 1, and are concaved facing downwardly, as best seen in FIGS. 3 and 4 so as to provide concaved lower surfaces 63 and 64 for receiving the fingers of a person which grasp the instrument.
Between the wings 61 and 62, the end plate is flat, being provided with generally cylindrical,'juxtaposed, merged abutment plates 65 and 66 which limit the upward or rearward movement of the carpule 20. Furthermore, these abutment plates 65 and 66 slidably receive, through their respective centers, a pair of parallel disposed spaced piston rods 67 and 68 of the plunger 70. The forward end of the piston rods 67 and 68 are provided with flat plate like pistons 71 and 72 which abut against the inner surfaces of the abutment plates 65, 66 to limit outward movement of the plunger and abut the plugs 27, 28.
The outer ends of the piston rods 67 and 68 are connected by a common transversely extending handle 73. The handle 73 is disposed in approximately a parallel position with respect to the end plate 60. The distance from the handle 73 to the end plate 60 is the stroke of the plunger 70, being such that with the plunger extended, the instrument may be grasped in a persons hand with a pair of fingers of his hand looping under and receiving the surfaces 63 and 64 as the ball of the hand or the thumb receives the top or outer surface of the handle 73. In such a manner, the piston rods 67' and 68 may be urged axially inwardly from a position shown in FIGS. 1, 3 and 4 to a position in which the handle 73 is disposed adjacent the end plate 60, whereby the pistons 71 and 72 are urged their full distance through the cylinders 21 and 22, urging plugs 27, 28 downwardly or inwardly toward and against plugs 29, 30. The forward or downward movement of the carpule 20 is arrested by the cap 50.
The forward end of cap 50 is cylindrical, being provided with external threads 51 which receive the internal threads 52 (seen in FIG. 3) of a collar or sleeve 53 of the nozzle assembly 80.
In more detail, the clamping collar or the sleeve 53 includes a cylindrical portion 54 having the internal threads 52 and having its outer surface knurled, at numeral 55, so that it may be readily rotated on and off the cap 50. The forward end portion of the sleeve 53 is provided with a flat plate 56, the central portion of which is provided with a circular aperture 57 for receiving the nozzle assembly, denoted by numeral 80. The inner surface of plate 56, which defines the central opening therein, is tapered outwardly toward the discharge end of the syringe.
The nozzle assembly includes a clear plastic mixing tube 81, having an inner frustoconical or flaring proximal cylindrical hollow tubular end 82 which is received in the tapered central hole of plate 56. The distal-end 83 of the mixing tube 81 tapers axia'lly outwardly and is curved to terminate in a small radially facing discharge opening 84, through which the mixed material is discharged.
The nozzle assembly 80 also includes an end bearing or spider 85, seen best in FIGS. 2 and 3, received within the cylindrical portion of the mixing tube 81. The spider 85 includes a central journal or hub from which radiate circumferentially equally spaced outwardly extending arms. The ends of the arms of spider 85 engage the inner surface of the mixing tube 81. The journal portion of the spider 85 receives the end of a central axially disposed shaft 86 of a rotatable agitator, denoted generally by numeral 87. The shaft 86 is provided, as best seen in FIG. 2, with a plurality of radially extending mixing fingers or rods 88. Rods 88 are axially and circumferentially spaced along the length of shaft 86 to provide effective means for mixing the base material and accelerator and for advancing the mixed material through tube 81.
The shaft 86 projects throughout substantially the entire length of the mixing tube 81, terminating at its lower end in the journal of spider 85. Its upper or inner end extends through the tapered proximal end 82, being journaled by a cone shaped or frustoconical journal block, denoted by numeral 90. The inner end or protruding end of the shaft 86 passes through and beyond block 90 and is splined at numeral 89, so that it may be received in the circumferential spaced lands and grooves in the center of a drive pinion 90, seen in FIGS. 1, 3 and 6.
Pinion 91 is disposed within a central counterbored recess of the cap 50. The teeth of pinion 91 mesh with a laterally off-set drive cog 92 which is also recessed in cap 50. The drive cog 92 is received on the end of a drive shaft 93 extending from an electrical motor 94 which is nestled between the convexed outer surfaces of the lobes of cradle member 11.
A motor housing 100, the inner edge portion of which conforms to outer surface of the cradle member 11, encases the motor 94, the housing 100 being sufficiently large that it also receives the A batteries 96 and 97, on opposite sides of motor 94, as illustrated in FIG. 4. The housing 100 thus confines the motor 94 in place for driving, by the cog wheels 92 and pinion 91, the shaft 87. Coil springs 98 and 99 in housing 100 urge the batteries 96 and 97 into their appropriate positions.
As seen in FIG. 3, the pinion 91 is carried for rotation by a stub shaft 95 which projects through a central opening in the cap 50, the stub shaft 95 having an enlarged retainer flange 101 on its end for preventing outward movement of pinion 91.
On opposite sides of the splined end 89 of shaft 87, the conical journal block 90 is provided with spaced, parallel, outwardly projecting eduction tubes 102 and 103, the ends of which are beveled at numerals 104 and 105, respectively, so as to provide pointed ends which are adapted to penetrate the end plugs 29 and 30, respectively, of the carpule when the carpule 20 is inserted into the cradle member 11 or when the mixing nozzle 80 is installed in place on cap 50. The eduction tubes 102 and 103 are disposed parallel to each other and are equally spaced on opposite sides of the major axes of the syringe. These tubes 102 and 103 communicate with channels 106 and 107, on the surface of journal block 90, which in turn communicate with the interior mixing chamber of the mixing tube 81, adjacent the proximal end 82.
The cap 50 is provided with a pair of parallel apertures for holes 108 and 109, seen best in FIG. 1, through which the eduction tubes 102 and 103 pass.
Since the eduction tubes 102 and 103 are longer than the thickness of cap 50, they project through the plugs 29 and 30 so as to terminate within the cylinders 21 and 22, respectively. Therefore, downward movement of the plunger 70, will urge the liquid from the respective chambers of cylinders 21 and 22, through the eduction tubes 102 and 103 and thence down the passageways 106 and 107, respectively, so that they are co-mingled as they enter the cylindrical part of the mixing tube 81. The rotation of motor 94 through its gear train, including cog wheel 92 and pinion 91, rotates the shaft 86 thereby causing the rods 88 to travel in rotary paths so as to mix the two ingredients fed into the mixing tube.
Further, depression of plunger urges this mixed material out of the discharge opening 84 of the mixing tube.
By regulating the distance traveled by the plunger 70, the quantity of material mixed and discharged from the mixing tube 81 may be quite accurately regulated.
In FIGS. 7, 8 and 9 are three different ways of supplying current to the motor 94. In each instance, there is a lever 120, mounted for pivoting on a transverse pivot pin 121 carried by cradle member 11.
One end of lever projects inwardly of cradle member 11 and terminates in the central portion thereof, so as to be urged upwardly or outwardly by coiled spring 122, seen in FIG. 3. The upward movement of the inner arm, however, is arrested by the handle 60. The outer end of lever 120 protrudes below the wing 62 of the handle 60 and is normally in spaced relationship thereto so that when the lever 120 is urged into juxtaposition or to a position contiguous with the wing 62, a circuit is made to energize or actuate a motor 64.
In the embodiment illustrated in FIG. 7, a normally open switch 123 is closed when the lever 120 is pivoted in a counterclockwise direction. This switch 123 is in series with the batteries 96, 97 and motor 94. In more detail, one wire 124 connected to one terminal of switch 123 is connected to the negative side of battery 196. The other wire 125, leading from the other terminal of switch 123 is connected to the motor 94. The motor, in turn, is connected to a positive terminal of battery 97 via wire 126 while the two batteries are arranged in series,- through wire 127. Hence, the closing of switch 123 completes a circuit to the motor 94. Since the spring 122 urges the lever in a clockwise direction, the switch 123 is normally open until the lever is rotated, as aforesaid.
In FIG. 8, it will be seen that if desired the motor may be driven from a power pack illustrated generally by numeral 130. Current is supplied to the power pack at intervals by terminals 131 and 132. The switch 133 completes a circuit from the power pack to the motor 194 to drive the gear train heretofore described.
If desired, the motor may be connected through an extension cord (not shown) which connects the motor 294 to line current from an external source. In such an arrangement, the terminals 141 and 142 supply current by normally opened switch 143 and fuse 144 to the motor 294. It will be understood that the lever, such as lever 120, closes switch 143 and that the springs, such as spring 122 in FIG. 3, opens the switch 143 when the lever 120 is not depressed. It will also be understood that the motor 294 functions in identical fashion to the motor 94. g
It is now seen that when carpule 20 is installed in the cradle 1 l, the axes of pistons 6, 7 and 8 are respectively aligned longitudinally of the syringe with the axes of cylinders 21 and 22. Also'the axes of passageways 108 and 109 are aligned respectively with the axes of cylinders 21 and 22. Therefore, the axes of eduction tubes 102 and 103 are aligned respectively with the axes of cylinders 21 and 22.
Furthermore, one component axis passing through piston 67, cylinder 21, passageway 108 and eduction tube 102 is on one side parallel to the major axis of the syringe, i.e. the axis of shaft 86, while the other component axis passing through piston 68, cylinder 22, passageway 109 and eduction tube 103 is equidistance from and parallel to the major axes on the other side, thereof.
It will also be observed that when plunger 70 is in its most retracted position the pistons 71 and 72 are recessed into cavities in the plates 65 and 66 so that exposed surfaces of pistons 71 and 72 are in a common plane with the inner surface of plates 65 and 66. Also, the distance from plates 65, 66 to cap 50 mounted on opposite ends of cradle 11, is slightly greater than the length of carpule so that it may be snugly received by the cradle 11.
OPERATION From the foregoing description, the operation of the present device is quite apparent. First, a carpule 20, containing the base in one cylinder 21 and the accelerator in another cylinder 22, is installed in the cradle member 11. Then the cover 12 is closed thereover, the detent, including latch 34, latching the cover in place in apposition to the cradle member 11. This confines the double barrel carpule 20 in place, aligning the slidable plugs 27 and 28 with the pistons 71 and 72. It will be understood, of course, that prior to the installation of the carpule 20 in place, the plunger 70 must be retracted to its outermost position, as shown in FIG. 1. It is also to be understood that the nozzle assembly 80 is not installed, at this stage.
After the carpule 20 has been installed and clamped in place by closing of the cover-12, the nozzle assembly 80 is installed by inserting the eduction tubes 102 and 103 through the passageways 108 and 109 and thence through the central portions of the stationary plugs 29 and 30 so that the pointed tips or points 104 and 105 pass through the plugs 29 and 30 and terminate within the chambers of the cylinders 21 and 22.
Thereafter, the collar 53 is threaded onto the cap 50. Of course, the inserting of the eduction tubes 102 and 103 through the passageways 108 and 109 automatically align the spline 89 so that it will be received in the lines and grooves of the pinion 91. When the syringe is ready to be used, the operator grasps the syringe with his fingers engaging the wings 61 and 62, one finger looping over the lever 120. The base of the thumb of the operators hand can rest against the handle 73 so upon contracting of the fingers of the hand, the plunger 70 will be urged inwardly, while simultaneously therewith the lever 120 is depressed against the wing 62 so as to actuate the motor 91, 191 or 291, as the case may be. This commences rotation of shaft 87 so that the mixing rods 88 mix the material as such material is discharged simultaneously through the eduction tubes 102 and 103 and thence via passageways 106 and 107 into the chamber of the mixing tube 81. Thence, as explained above, the thoroughly mixed accelerator and base material is discharged from opening 84.
The syringe, thus described, is of such a size that the nozzle assembly and the body of the syringe may be inserted into the open mouth of a patient so that the mixed material may be directed against the appropriate tooth for making an impression of such tooth.
Since the material is not exposed to the atmosphere in the mixing tube, no appreciable odor is apparent from the mixing thereof.
When the operation of the device is completed, the plunger may be retracted quite readily and the nozzle assembly removed.
In some instances, it is only necessary to remove from the nozzle assembly, the mixing tube, so that it may be flushed out, and the agitator shaft 87 washed. Since the passageways 106 and 107 open outwardly, once the mixing tube has been removed, these passageways may be flushed out as well as the eduction tubes 102 and 103. The nozzle assembly, illustrated in FIG. 2, is so inexpensive, however, that it may be disposed of in toto so that a sterile and clean nozzle assembly can be used for each successive patient. Also, the carpules 20 are readily removed by the opening of cover 12 and replaced for successive patients or successive operations of the plunger.
What is claimed is:
1. A mixing syringe comprising a syringe body including a pair of body members, a hinge disposed along and joining the sides of said members, said members forming a cradle and a cover, said cover being movable in an arcuate path to and away from said cradle, the inside surfaces of said members each including a pair of concave surfaces joined along a common convex central ridge extending longitudinally of said member, a carpule received between said members, said carpule including a pair of hollow, cylindrical parallel disposed barrels open at both ends, a partition joining said barrels for maintaining the same in their parallel relationsip, a cap at one end of said body mounted on one body member, a transversely extending plate mounted on said one body member at the opposite end thereof from said cap, the distance between said handle and said cap being approximately the length of said carpule, said plate extending outwardly of said one member on both sides thereof, a plunger including a pair of spaced parallel slidable pistons carried by'said plate, a handle joining the outer ends of said piston so as to maintain the same in parallel relationship, said ,carpules including a pair of plugs in the ends of both of said cylinders and a fluid material within said carpule cylinders, a pair of said plugs being disposed adjacent said pistons when said carpule is installed in said one member and being movable towards the other plugs of said cylinders when said plunger is pushed inwardly of said one member, a removable nozzle assembly mounted on said cap, a collar, on said cap for maintaining said nozzle assembly in position on said cap, said nozzle assembly including a mixing tube, an agitator within said mixing tube, said agitatorincluding a shaft disposed along the axis of said tube and agitator members extending from said shaft, a spider within the distal end of said mixing tube receiving one end of said shaft, a journal block within the other end of said mixing tube, said shaft extending through said journal block and therebeyond, said shaft terminating in the splined end, said journal block and the proximal end of said mixing tube being retained in place by said collar, a pair of eduction tubes on opposite sides of said shaft and extending from said journal block, said journal block being provided with a pair of passageways communicating with said eduction tubes, respectively, and also communicating with the proximal end of said mixing tube, said eduction tubes extending parallel to each other and terminating in pointed ends, said cap being provided with passageways, said passageways receiving said eduction tubes when said nozzle assembly is mounted on said cap, said eduction tubes being of sufficient length that they penetrate through the plugs in the ends of said cylinders when said carpule is installed in said one member and when said nozzle assembly is installed on said cap, a
gear train within said cap, said gear train receiving the splined end of said shaft when said nozzle assembly is mounted on said cap, said mixing tube being provided at its distal end with an opening through which a mixture of the fluid materials contained in said carpule which are fed through said eduction tubes and said passageways in this mixing tube are discharged therefrom, a motor within said body for driving said gear train, and detent means for maintaining said body members in a closed position around said carpule.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1555711 *||Oct 26, 1921||Sep 29, 1925||Hershinger Harry B||Grease gun|
|US3035775 *||Jun 5, 1959||May 22, 1962||Ici Ltd||Spray gun with mixing means|
|US3130872 *||Feb 6, 1962||Apr 28, 1964||R C Can Co||Device for discharging viscous fluid|
|US3166221 *||Apr 24, 1962||Jan 19, 1965||Leo Pharm Prod Ltd||Double-tube dispensing container|
|US3311265 *||Jun 3, 1965||Mar 28, 1967||Chem Dev Corp||Double-barreled dispensing gun|
|US3390814 *||Sep 24, 1965||Jul 2, 1968||Chem Dev Corp||Mixing device|
|DE1126082B *||Dec 16, 1960||Mar 22, 1962||Dr Hermann Neuhierl||Kuechenmaschine|
|GB896993A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3952920 *||Dec 30, 1974||Apr 27, 1976||Bridgeport Chemical Corporation||Dispenser for multi-component products|
|US4067479 *||Jul 31, 1975||Jan 10, 1978||Products Research & Chemical Corporation||Two part material meter-mix dispenser apparatus|
|US4090129 *||Jan 28, 1977||May 16, 1978||University Of Virginia||Stopped-flow reaction apparatus utilized in conjunction with continuous-flow resistive-particle counting apparatus|
|US4197942 *||Nov 7, 1977||Apr 15, 1980||Picker Corporation||Containerized fluid supply for fluid mixing and dispensing system|
|US4260077 *||Oct 4, 1979||Apr 7, 1981||Aelco Corporation||Dual separable dispenser|
|US4621747 *||Jun 28, 1984||Nov 11, 1986||Tebel Machinefabrieken B.V.||Apparatus for charge-wise dosing a metered volume quantity of a flowing medium continuously supplied to the apparatus under delivery pressure|
|US4655372 *||Sep 21, 1984||Apr 7, 1987||The Joy Of Painting||Paint dispenser|
|US4759633 *||Mar 6, 1986||Jul 26, 1988||Alfred Schmid||Apparatus and process for metering and mixing two different materials that are pasty or of low to high viscosity|
|US4846373 *||Oct 15, 1987||Jul 11, 1989||Penn Laurence R||Apparatus for proportioning or for proportioning and mixing plural different fluid compositions|
|US4871090 *||Jul 21, 1988||Oct 3, 1989||Hilti Aktiengesellschaft||Cartridge assembly for flowable masses|
|US4902281 *||Aug 16, 1988||Feb 20, 1990||Corus Medical Corporation||Fibrinogen dispensing kit|
|US4948016 *||Sep 9, 1988||Aug 14, 1990||Sashco, Inc.||Laminated materials container|
|US4951843 *||Aug 16, 1989||Aug 28, 1990||Sealant Equipment & Engineering, Inc.||Disposable mixing chamber liner and paddle for a dynamic mixing and dispensing gun|
|US4974752 *||Nov 27, 1989||Dec 4, 1990||Sirek Andrew J||Heated caulk dispensing gun|
|US4979942 *||Oct 16, 1989||Dec 25, 1990||Johnson & Johnson Medical, Inc.||Two component syringe delivery system|
|US5064098 *||Feb 23, 1990||Nov 12, 1991||Physical Systems, Inc.||Dual component dispenser gun|
|US5080262 *||Jan 16, 1990||Jan 14, 1992||Thera Patent Gmbh & Co. Kg Gesellschaft Fur Industrielle Schutzrechte||Mixing dispenser for pasty masses|
|US5161715 *||Mar 25, 1991||Nov 10, 1992||Giannuzzi Anthony C||Double-barreled epoxy injection gun|
|US5240141 *||Jun 24, 1992||Aug 31, 1993||Minnesota Mining And Manufacturing Company||Hand-held dispenser with pivotal cover for collapsible tubes|
|US5249862 *||Dec 23, 1991||Oct 5, 1993||Thera Patent Gmbh & Co.Kg Gesellschaft Fur Industrielle Schutzrechte||Dynamic mixer|
|US5271527 *||Aug 18, 1992||Dec 21, 1993||Habley Medical Technology Corporation||Reusable pharmaceutical dispenser with full stroke indicator|
|US5286105 *||Dec 23, 1991||Feb 15, 1994||Thera Patent Gmbh & Co. Kg Gesellschaft Fuer Industrielle Schutzrechte||Apparatus for mixing and dispensing multiple-component substances|
|US5286257 *||Nov 18, 1992||Feb 15, 1994||Ultradent Products, Inc.||Syringe apparatus with detachable mixing and delivery tip|
|US5286258 *||Mar 8, 1991||Feb 15, 1994||Habley Medical Technology Corporation||Multipharmaceutical delivery system|
|US5301842 *||Feb 21, 1992||Apr 12, 1994||Frank Ritter||Multicomponent cartridge for plastic materials|
|US5314412 *||May 16, 1991||May 24, 1994||Novo Nordisk A S||Manifold for a two barrel syringe|
|US5328459 *||May 6, 1993||Jul 12, 1994||Laghi Aldo A||Apparatus and method for dispensing and aspirating high viscosity materials|
|US5332124 *||May 17, 1993||Jul 26, 1994||Chesebrough-Pond's, Usa Co., A Division Of Conopco, Inc.||Multi-cavity dispensing refill cartridge|
|US5335827 *||Dec 22, 1992||Aug 9, 1994||Chesebrough-Pond's Usa Co., A Division Of Conopco, Inc.||Multi-cavity dispensing refill cartridge|
|US5336014 *||Nov 18, 1992||Aug 9, 1994||Keller Wilhelm A||Manually operated dispensing appliance, in particular for a double dispensing cartridge for two-component substances|
|US5409465 *||Feb 7, 1994||Apr 25, 1995||Boggs; Michael S.||Impression syringe|
|US5478323 *||Nov 2, 1994||Dec 26, 1995||Eli Lilly And Company||Manifold for injection apparatus|
|US5542934 *||Jun 2, 1995||Aug 6, 1996||Silver; Richard M.||Multiple carpule hypodermic syringe|
|US5547107 *||Jan 4, 1993||Aug 20, 1996||Package Research, Inc.||Dispenser for flowable materials|
|US5582596 *||Sep 24, 1993||Dec 10, 1996||Juridical Foundation The Chemo-Sero-Therapeutic Research Institute||Applicator for applying a biocompatible adhesive|
|US5656035 *||Apr 25, 1995||Aug 12, 1997||Avoy; Donald R.||Refillable fibrinogen dispensing kit|
|US5814022 *||Feb 6, 1996||Sep 29, 1998||Plasmaseal Llc||Method and apparatus for applying tissue sealant|
|US5875928 *||Jan 5, 1996||Mar 2, 1999||Bayer Aktiengesellschaft||Device for mixing and discharging a molding composition|
|US5881920 *||May 6, 1997||Mar 16, 1999||The Plastek Group||Product dispenser having separable refill cartridge|
|US5881921 *||Jul 31, 1997||Mar 16, 1999||The Plastek Group||Product dispenser having separable refill top loading cartridge|
|US5967373 *||May 6, 1998||Oct 19, 1999||The Plastek Group||Product dispenser having separable refill cartridge and staging and locking structure|
|US6039215 *||Jun 12, 1998||Mar 21, 2000||The Procter & Gamble Company||Dual product pump dispenser with multi-outlet closure for product separation|
|US6132396 *||Aug 3, 1998||Oct 17, 2000||Plasmaseal Llc||Apparatus for applying tissue sealant|
|US6234994 *||Sep 9, 1997||May 22, 2001||Omrix Biopharmaceuticals Sa||Multicomponent tissue adhesive application device and holder for such device|
|US6290101 *||Sep 1, 2000||Sep 18, 2001||Peter J. Chang||Cartridge stabilizing plate for dual barrel dispensers|
|US6331172||Apr 14, 1997||Dec 18, 2001||Baxter International Inc.||Applicator for dispensing measured quantities with use of controlled suction|
|US6394643 *||Oct 14, 1999||May 28, 2002||Kettenbach Gmbh & Co. Kg||Device for mixing two pasty materials, especially for mixing a dental impression material with a catalyst material|
|US6394982||Jan 31, 2000||May 28, 2002||United States Surgical Corporation||Fibrin glue applicator system|
|US6443612 *||Nov 21, 2000||Sep 3, 2002||Wilhelm A. Keller||Dynamic mixer|
|US6454739 *||Sep 5, 2000||Sep 24, 2002||Korea Greencross Corp.||Fibrin sealant delivery device|
|US6458095||Mar 10, 2000||Oct 1, 2002||3M Innovative Properties Company||Dispenser for an adhesive tissue sealant having a housing with multiple cavities|
|US6471670||Oct 4, 1999||Oct 29, 2002||Karl Enrenfels||Fibrin sealant applicator system|
|US6475183 *||May 7, 1999||Nov 5, 2002||Baxter International Inc.||Direct dual filling device for sealing agents|
|US6523992 *||Nov 13, 2000||Feb 25, 2003||Kettenbach Gmbh & Co. Kg||Device for mixing two pasty substances, particularly for mixing a dental impression substance with catalyst substance|
|US6527749||Jun 19, 2000||Mar 4, 2003||United States Surgical Corporation||Two component dispenser system|
|US6540395 *||Dec 22, 2000||Apr 1, 2003||Ernst Mühlbauer KG||Dynamic mixer for dental impression compounds|
|US6569113||Aug 9, 2002||May 27, 2003||3M Innovative Properties Company||Dispenser for an adhesive tissue sealant|
|US6612465 *||Apr 11, 2002||Sep 2, 2003||Dentsply Research & Development Corp.||Multi-component mixing storage and dispensing device|
|US6620138 *||Mar 17, 2000||Sep 16, 2003||Disetronic Licensing Ag||Infusor, catheter means and catheter head|
|US6644365||Apr 19, 2002||Nov 11, 2003||Baxter International, Inc.||Tilting direct dual filling device|
|US6648852||Mar 27, 2003||Nov 18, 2003||3M Innovative Peroperties Company||Dispenser for an adhesive tissue sealant|
|US6723067||Jul 26, 2001||Apr 20, 2004||David H. Nielson||Apparatus for delivering aerosolized fibrin endoscopically to a wound|
|US6764467||Dec 16, 1998||Jul 20, 2004||United States Surgical Corporation||Fibrin mixture and dispenser assembly|
|US6837612 *||Dec 30, 2002||Jan 4, 2005||Kettenbach Gmbh & Co. Kg||Device for mixing two paste-like compounds, in particular for mixing a dental-molding compound with a catalyzing compound|
|US6848906 *||Nov 27, 2001||Feb 1, 2005||Heraeus Kulzer Gmbh & Co. Kg||Syringe for the metered delivery of dental materials|
|US6854621||Aug 14, 2002||Feb 15, 2005||Mixpac Systems Ag||Cartridge dispenser including drive for dynamic mixer|
|US6874657 *||Apr 1, 2002||Apr 5, 2005||Zlb Behring Gmbh||Biological sealant storage and dispensing system|
|US6884230||May 2, 2000||Apr 26, 2005||Baxter International Inc.||Dispensing head for a tissue sealant applicator and process of use|
|US6921380||Sep 29, 1999||Jul 26, 2005||Baxter International Inc.||Component mixing catheter|
|US6932243 *||Jul 9, 2002||Aug 23, 2005||Mixpac Systems Ag||Dispensing assembly with dynamic mixer|
|US7018357||Feb 27, 2002||Mar 28, 2006||Tyco Healthcare Group Lp||External mixer assembly|
|US7025755||May 31, 2002||Apr 11, 2006||Baxter International Inc.||Medical suctioning apparatus and methods of use|
|US7077339||Feb 3, 2003||Jul 18, 2006||Biomet, Inc.||Spray applicator|
|US7081103||Nov 4, 2002||Jul 25, 2006||Baxter International Inc.||Direct dual filling device for sealing agents|
|US7207969||Dec 2, 2002||Apr 24, 2007||Baxter International Inc.||Direct dual filling device for sealing agents|
|US7320541 *||Aug 11, 2004||Jan 22, 2008||3M Espe Ag||Mixer element for a mixer for multi-component pastes, and mixer using the same|
|US7322956 *||Jul 14, 2004||Jan 29, 2008||Straumann Holding, Ab||System and method for mixing at least four components|
|US7604185||Sep 14, 2005||Oct 20, 2009||Btg International Ltd.||Generation of therapeutic microfoam|
|US7635343 *||Jan 27, 2006||Dec 22, 2009||Arteriocyte Medical Systems, Inc.||Fluid dispenser|
|US7699803 *||Jan 3, 2008||Apr 20, 2010||Medtronic Vascular, Inc.||Devices and methods for injection of multiple-component therapies|
|US7712635 *||Jun 20, 2006||May 11, 2010||Kovac Karen S||Quick load caulking gun cartridge holder|
|US7731986||Nov 17, 2004||Jun 8, 2010||Btg International Ltd.||Therapeutic foam|
|US7763269||Nov 17, 2004||Jul 27, 2010||Btg International Ltd.||Therapeutic foam|
|US7766900||Sep 8, 2005||Aug 3, 2010||Biomet Manufacturing Corp.||Method and apparatus for application of a fluid|
|US7828178 *||May 7, 2010||Nov 9, 2010||Kovac Karen S||Quick load cartridge holder for a caulking gun|
|US7842282||Oct 13, 2006||Nov 30, 2010||Btg International Limited||Generation of therapeutic microfoam|
|US7842283||Oct 13, 2006||Nov 30, 2010||Btg International Limited||Generation of therapeutic microfoam|
|US7959370||Sep 18, 2008||Jun 14, 2011||Dentsply International, Inc.||Packaged dental composition|
|US7963938||Nov 13, 2003||Jun 21, 2011||Chemische Fabrik Kreussler & Co.||Device for producing medicinal foam|
|US7972057 *||Jul 18, 2007||Jul 5, 2011||Ernst Muhlbauer Gmbh & Co. Kg||Device for producing a multi-component compound|
|US8034396||Feb 10, 2009||Oct 11, 2011||Tyco Healthcare Group Lp||Bioadhesive composition formed using click chemistry|
|US8048439||May 13, 2005||Nov 1, 2011||Btg International Ltd.||Therapeutic foam|
|US8057426 *||Jan 3, 2008||Nov 15, 2011||Medtronic Vascular, Inc.||Devices and methods for injection of multiple-component therapies|
|US8088099 *||Nov 23, 2009||Jan 3, 2012||Arteriocyte Medical Systems, Inc.||Fluid dispenser|
|US8091801||Jun 18, 2009||Jan 10, 2012||Btg International Limited||Generation of therapeutic microfoam|
|US8100295||Mar 23, 2007||Jan 24, 2012||Medmix Systems Ag||Dispensing assembly with removably attachable accessories|
|US8104642 *||Aug 31, 2005||Jan 31, 2012||Quikshot Packaging Pty Ltd||Beverage dispenser and method|
|US8147122 *||Mar 4, 2004||Apr 3, 2012||Dentsply International Inc.||Dispensing and mixing tip for reactive componets|
|US8177747||Nov 30, 2010||May 15, 2012||Alcon Research, Ltd.||Method and apparatus for drug delivery|
|US8182769||Apr 4, 2008||May 22, 2012||Biomet Biologics, Llc||Clean transportation system|
|US8197122||Apr 13, 2009||Jun 12, 2012||Tyco Healthcare Group Lp||Dynamic mixing applicator|
|US8246629 *||Mar 31, 2003||Aug 21, 2012||Cemvac System Ab||Feeding device for a monomer|
|US8292846 *||Oct 28, 2010||Oct 23, 2012||Tyco Healthcare Group Lp||Applicator tip|
|US8322909||Sep 21, 2005||Dec 4, 2012||3M Deutschland Gmbh||Mixer for multi-component pastes, kit, and method of mixing paste components|
|US8323677||Apr 23, 2010||Dec 4, 2012||Btg International Ltd.||Therapeutic foam|
|US8372036||May 5, 2010||Feb 12, 2013||Alcon Research, Ltd.||Multi-layer heat assembly for a drug delivery device|
|US8383163||Dec 19, 2008||Feb 26, 2013||Ultradent Products, Inc.||Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent|
|US8394052||Aug 16, 2010||Mar 12, 2013||Ultradent Products, Inc.||Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods|
|US8444620||Jul 8, 2010||May 21, 2013||Biomet Biologics, Llc||Method and apparatus for application of a fluid|
|US8454558||Apr 26, 2007||Jun 4, 2013||Ultradent Products, Inc.||Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems and methods|
|US8512680||Jul 16, 2007||Aug 20, 2013||Btg International Ltd.||Injectables in foam, new pharmaceutical applications|
|US8512728||Feb 19, 2010||Aug 20, 2013||Sofradim Production||Method of forming a medical device on biological tissue|
|US8518272||Apr 4, 2008||Aug 27, 2013||Biomet Biologics, Llc||Sterile blood separating system|
|US8518349 *||Apr 17, 2012||Aug 27, 2013||Lanny Johnson||Use of autologous sediment from fluid aspirates as vehicles for drug delivery|
|US8535477||Feb 19, 2010||Sep 17, 2013||Sofradim Production||Medical devices incorporating functional adhesives|
|US8561845 *||Dec 22, 2010||Oct 22, 2013||3M Innovative Properties Company||Capsule for two-component materials|
|US8632511||May 5, 2010||Jan 21, 2014||Alcon Research, Ltd.||Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device|
|US8648144||Feb 22, 2010||Feb 11, 2014||Sofradim Production||Crosslinked fibers and method of making same by extrusion|
|US8651338 *||Jun 1, 2010||Feb 18, 2014||Sanofi-Aventis Deutschland Gmbh||Delivery of two or more medicaments through a single dose selection and single dispense interface|
|US8663689||Feb 19, 2010||Mar 4, 2014||Sofradim Production||Functionalized adhesive medical gel|
|US8684233 *||Oct 15, 2009||Apr 1, 2014||Saraya Co., Ltd.||Fluid container unit and method for injecting different kinds of fluids into fluid usage equipment|
|US8703827||May 12, 2006||Apr 22, 2014||Btg International Ltd.||Therapeutic foam|
|US8777906 *||Jun 22, 2011||Jul 15, 2014||Robin Scott Gray||Syringe with inspection window|
|US8795331||Mar 24, 2011||Aug 5, 2014||Covidien Lp||Medical devices incorporating functional adhesives|
|US8807394 *||Apr 21, 2011||Aug 19, 2014||3M Innovative Properties Company||System comprising a mixing and dispensing device and a material container|
|US8820581 *||Dec 13, 2012||Sep 2, 2014||Sulzer Mixpac Ag||Dispensing device for multi-component cartridges|
|US8852561||Feb 7, 2013||Oct 7, 2014||Ultradent Products, Inc.||Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent|
|US8865857||Jun 30, 2011||Oct 21, 2014||Sofradim Production||Medical device with predefined activated cellular integration|
|US8877170||Feb 19, 2010||Nov 4, 2014||Sofradim Production||Medical device with inflammatory response-reducing coating|
|US8956603||Feb 22, 2010||Feb 17, 2015||Sofradim Production||Amphiphilic compounds and self-assembling compositions made therefrom|
|US8968733||Feb 19, 2010||Mar 3, 2015||Sofradim Production||Functionalized surgical adhesives|
|US8968818||Feb 19, 2010||Mar 3, 2015||Covidien Lp||Medical devices having activated surfaces|
|US8969473||Feb 22, 2010||Mar 3, 2015||Sofradim Production||Compounds and medical devices activated with solvophobic linkers|
|US9005178||Oct 31, 2008||Apr 14, 2015||3M Innovative Properties Company||Dispensing cartridge|
|US9028457||May 21, 2013||May 12, 2015||Biomet Biologics, Llc||Method and apparatus for application of a fluid|
|US9039979||Feb 22, 2010||May 26, 2015||Sofradim Production||Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices|
|US9044549 *||Apr 19, 2011||Jun 2, 2015||Noviscens Ab||Syringe dispenser, stand and application plate for said syringe dispenser and method for its use|
|US9095654 *||Aug 14, 2013||Aug 4, 2015||Allergan, Inc.||Syringe for mixing and dispensing adipose tissue|
|US9180172 *||Dec 15, 2011||Nov 10, 2015||Ams Research Corporation||Treatment of Peyronies disease|
|US9211487||Aug 26, 2013||Dec 15, 2015||Biomet Biologics, Llc||Sterile blood separating system|
|US9216226||Feb 3, 2015||Dec 22, 2015||Sofradim Production||Compounds and medical devices activated with solvophobic linkers|
|US9220577||Jan 15, 2013||Dec 29, 2015||Ultradent Products, Inc.||Syringe-to-syringe mixing systems and related apparatus and methods|
|US9247931||Jun 29, 2011||Feb 2, 2016||Covidien Lp||Microwave-powered reactor and method for in situ forming implants|
|US9272074||Mar 24, 2011||Mar 1, 2016||Sofradim Production||Surgical fasteners and methods for sealing wounds|
|US9273191||Feb 22, 2010||Mar 1, 2016||Sofradim Production||Medical devices with an activated coating|
|US9289922||Jan 8, 2007||Mar 22, 2016||Atomic Energy Of Canada Limited/Energie||Device and method for surface replication|
|US9375699||Feb 22, 2010||Jun 28, 2016||Sofradim Production||Apparatus and method of reacting polymers by exposure to UV radiation to produce injectable medical devices|
|US9415361||Nov 19, 2012||Aug 16, 2016||3M Innovative Properties Company||Mixer for multi-component pastes, kit, and method of mixing paste components|
|US9421296||Jan 23, 2014||Aug 23, 2016||Covidien Lp||Crosslinked fibers and method of making same by extrusion|
|US20020161335 *||Apr 1, 2002||Oct 31, 2002||Metzner Hubert J.||Biological sealant storage and dispensing system|
|US20020175186 *||Jul 9, 2002||Nov 28, 2002||Keller Wilhelm A.||Dynamic mixer|
|US20020190082 *||Aug 14, 2002||Dec 19, 2002||Ammann Patentanwalte Ag Bern||Cartridge dispenser including drive for dynamic mixer|
|US20030123323 *||Dec 30, 2002||Jul 3, 2003||Alexander Bublewitz||Device for mixing two paste-like compounds, in particular for mixing a dental-molding compound with a catalyzing compound|
|US20030139774 *||Dec 2, 2002||Jul 24, 2003||Epstein Gordon Howard||Direct dual filling device for sealing agents|
|US20040144801 *||Jan 16, 2004||Jul 29, 2004||Pierson Paul Richard||Mixing tip for dental materials|
|US20040159715 *||Feb 3, 2003||Aug 19, 2004||Leach Michael D.||Spray applicator|
|US20040257909 *||Mar 4, 2004||Dec 23, 2004||Pieroni Robert J.||Dispensing and mixing tip|
|US20050027240 *||Jul 14, 2004||Feb 3, 2005||Daniel Fehr||System and method for mixing at least four components|
|US20050049558 *||Jun 14, 2004||Mar 3, 2005||Michael Knee||Dispensing cartridge|
|US20050226095 *||Aug 11, 2004||Oct 13, 2005||Wagner Ingo W||Mixer element for a mixer for multi-component pastes, and mixer using the same|
|US20050226819 *||Jun 7, 2005||Oct 13, 2005||Pierson Paul R||Packaged dental composition|
|US20050228396 *||Mar 31, 2003||Oct 13, 2005||Soren Jonsson||Feeding device for a monomer|
|US20050232073 *||Jun 30, 2004||Oct 20, 2005||Wagner Ingo W||Dynamic mixer|
|US20060049269 *||Sep 14, 2005||Mar 9, 2006||Tariq Osman||Generation of therapeutic microfoam|
|US20060062736 *||Nov 17, 2004||Mar 23, 2006||Wright David D I||Therapeutic foam|
|US20060071023 *||Dec 19, 2003||Apr 6, 2006||Ernst Muhlbauer Gmbh * Co. Kg||Device for dispensing a mixed multi-component compound|
|US20060116646 *||Jun 28, 2005||Jun 1, 2006||Weiss Jennifer J||Bi-inoculator dual syringe clip|
|US20060178620 *||Nov 13, 2003||Aug 10, 2006||Chemische Fabrik Kreussler & Co., Gmbh||Device for producing medicinal foam|
|US20060253082 *||Jan 27, 2006||Nov 9, 2006||Mcintosh Kevin D||Fluid dispenser|
|US20060280690 *||Nov 17, 2004||Dec 14, 2006||Wright David D I||Methods of preparing a foam comprising a sclerosing agent|
|US20060283891 *||Jun 20, 2006||Dec 21, 2006||Kovac Karen S||Quick load caulking gun cartridge holder|
|US20070003488 *||Nov 17, 2004||Jan 4, 2007||Wright David D I||Methods of preparing a foam comprising a sclerosing agent|
|US20070003489 *||May 13, 2005||Jan 4, 2007||Wright David D I||Therapeutic foam|
|US20070031345 *||Oct 13, 2006||Feb 8, 2007||Harman Anthony D||Generation of therapeutic microfoam|
|US20070031346 *||Oct 13, 2006||Feb 8, 2007||Harman Anthony D||Generation of therapeutic microfoam|
|US20070041776 *||Oct 26, 2006||Feb 22, 2007||Pierson Paul R||Packaged dental composition|
|US20070104651 *||Nov 17, 2004||May 10, 2007||Wright David D I||Therapeutic foam|
|US20070244442 *||May 16, 2007||Oct 18, 2007||Chowhan Masood A||Device for Ophthalmic Drug Delivery|
|US20080031827 *||Jul 16, 2007||Feb 7, 2008||Maria Garcia-Olmedo Dominguez||Injectables in foam. New Pharmaceutical applications|
|US20080087683 *||Dec 14, 2007||Apr 17, 2008||3M Innovative Properties Company||Dynamic mixer|
|US20080145401 *||Feb 28, 2008||Jun 19, 2008||Tariq Osman||Generation of Therapeutic Microfoam|
|US20080161757 *||Jan 3, 2008||Jul 3, 2008||Medtronic Vascular, Inc.||Devices and Methods for Injection of Multiple-Component Therapies|
|US20080161772 *||Jan 3, 2008||Jul 3, 2008||Medtronic Vascular, Inc.||Devices and Methods for Injection of Multiple-Component Therapies|
|US20080267005 *||Apr 24, 2007||Oct 30, 2008||Tyco Healthcare Group Lp||Applicator system and method of use|
|US20090020440 *||Sep 18, 2008||Jan 22, 2009||Pierson Paul R||Packaged dental composition|
|US20090034357 *||Sep 21, 2005||Feb 5, 2009||Jens Gramann||Mixer for multi-component pastes, kit, and method of mixing paste components|
|US20090041827 *||Aug 1, 2008||Feb 12, 2009||Btg International Ltd.||Therapeutic Microfoam|
|US20090057338 *||Oct 31, 2008||Mar 5, 2009||3M Innovative Properties Company||Dispensing cartridge|
|US20090093788 *||Oct 1, 2008||Apr 9, 2009||Alcon Research, Ltd.||Thermal Coefficient Driven Drug Pellet Size For Ophthalmic Injection|
|US20090093789 *||Oct 1, 2008||Apr 9, 2009||Alcon Research, Ltd.||Method of Delivering A Rate And Temperature - Dependent Substance Into The Eye|
|US20090124704 *||May 12, 2006||May 14, 2009||William John Jenkins||Therapeutic foam|
|US20090191279 *||Dec 19, 2008||Jul 30, 2009||Ultradent Products, Inc.||Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent|
|US20090247651 *||Feb 10, 2009||Oct 1, 2009||Tyco Healthcare Group Lp||Bioadhesive Composition Formed Using Click Chemistry|
|US20090256006 *||Jun 18, 2009||Oct 15, 2009||Tariq Osman||Generation of therapeutic microfoam|
|US20090268546 *||Apr 13, 2009||Oct 29, 2009||Jon Reinprecht||Dynamic mixing applicator|
|US20090272759 *||Aug 31, 2005||Nov 5, 2009||Quickshot Packaging Pty Ltd.||Beverage dispenser and method|
|US20100076399 *||Nov 23, 2009||Mar 25, 2010||Arteriocyte Medical Systems, Inc.||Fluid dispenser|
|US20100091607 *||Jul 18, 2007||Apr 15, 2010||Sven Meyer||Device for producing a multi-component compound|
|US20100163579 *||Mar 23, 2007||Jul 1, 2010||Medmix Systems Ag||Dispensing Assembly with Removably Attachable Accessories|
|US20100212829 *||Feb 19, 2010||Aug 26, 2010||Sebastien Ladet||Medical devices incorporating functional adhesives|
|US20100215659 *||Feb 19, 2010||Aug 26, 2010||Sebastien Ladet||Functionalized surgical adhesives|
|US20100215709 *||Feb 19, 2010||Aug 26, 2010||Sebastien Ladet||Medical device with inflammatory response-reducing coating|
|US20100215748 *||Feb 19, 2010||Aug 26, 2010||Sebastien Ladet||Functionalized adhesive medical gel|
|US20100219210 *||May 7, 2010||Sep 2, 2010||Kovac Karen S||Quick load cartridge holder for a caulking gun|
|US20100307935 *||Aug 16, 2010||Dec 9, 2010||Ultradent Products, Inc.||Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods|
|US20110077672 *||Nov 16, 2010||Mar 31, 2011||Fleischman Sidney D||Devices For Installing Stasis Reducing Means In Body Tissue|
|US20110084094 *||Dec 22, 2010||Apr 14, 2011||3M Innovative Properties Company||Capsule for two-component materials|
|US20110139821 *||Sep 18, 2009||Jun 16, 2011||Medmix Systems Ag||Connector having mixing element for discharge arrangement|
|US20110253739 *||Oct 15, 2009||Oct 20, 2011||Suguru Nishio||Fluid container unit and method for injecting different kinds of fluids into fluid usage equipment|
|US20120101472 *||Jul 9, 2010||Apr 26, 2012||Schroeder Tania M||Multi-chamber cellular mixing and delivery system and method|
|US20120109053 *||Oct 28, 2010||May 3, 2012||Tyco Healthcare Group Lp||Applicator Tip|
|US20120125951 *||Jun 1, 2010||May 24, 2012||Sanofi-Aventis Deutschland Gmbh||Delivery of Two or More Medicaments Through a Single Dose Selection and Single Dispense Interface|
|US20120156178 *||Dec 15, 2011||Jun 21, 2012||Natalie Ann Borgos||Treatment of peyronies disease|
|US20120203167 *||Apr 17, 2012||Aug 9, 2012||Lanny Johnson||Use of autologous sediment from fluid aspirates as vehicles for drug delivery|
|US20120214124 *||Feb 21, 2011||Aug 23, 2012||Dr. Bryan W. McLelland||High Volume Carpule System|
|US20130037570 *||Apr 21, 2011||Feb 14, 2013||3M Innovative Properties Company||System comprising a mixing and dispensing device and a material container|
|US20130043282 *||Apr 19, 2011||Feb 21, 2013||Noviscens Ab||Syringe dispenser, stand and application plate for said syringe dispenser and method for its use|
|US20130161353 *||Dec 13, 2012||Jun 27, 2013||Sulzer Mixpac Ag||Dispensing device for multi-component cartridges|
|US20130309136 *||Apr 1, 2013||Nov 21, 2013||Boston Microfluidics||Sample processing methods and systems to collect and dilute a biological sample|
|US20140052059 *||Aug 14, 2013||Feb 20, 2014||Allergan, Inc.||Syringe for mising and dispensing adipose tissue|
|US20140117046 *||Aug 20, 2012||May 1, 2014||Sulzer Mixpac Ag||Cartridge, method of manufacturing same and multicomponent cartridge|
|US20150105749 *||May 16, 2013||Apr 16, 2015||Sanofi-Aventis Deutschland Gmbh||Dispense interface for an ejection device|
|USRE36235 *||May 27, 1992||Jun 29, 1999||Wilhelm Keller||Dispensing and mixing apparatus|
|DE3537381A1 *||Oct 21, 1985||May 22, 1986||Alfred Schmid Ag Plastikwerk||Vorrichtung und verfahren zum dosieren und mischen von zwei unterschiedlichen, pastoesen oder niedrig oder hoeher viskosen massen|
|DE3823708A1 *||Jul 13, 1988||Jan 18, 1990||Licentia Gmbh||Verfahren zum herstellen eines austrittsquerschnitts fuer in eine verschlussmembran enthaltenden behaeltnissen befindliche substanzen|
|DE4312740A1 *||Apr 20, 1993||Oct 27, 1994||Gurit Essex Ag||Vorrichtung zum Entleeren von Kartuschen|
|DE9417665U1 *||Nov 7, 1994||Jan 26, 1995||Wegener Gmbh||Vorrichtung zum Verarbeiten und Austragen von wenigstens zwei pastösen Komponenten|
|DE19618693A1 *||May 9, 1996||Nov 13, 1997||Upat Max Langensiepen Kg||Cartridge for interchangeable twin component masses in foil bags|
|DE19618718B4 *||May 9, 1996||Jan 13, 2005||3M Espe Ag||Verfahren zur Anmischung von Abformmassen|
|DE19912434B4 *||Mar 19, 1999||Oct 24, 2013||Roche Diagnostics Gmbh||Infusionsgerät, Kathetereinrichtung und Katheterkopf|
|DE29617872U1 *||Oct 16, 1996||Dec 12, 1996||Dreve Otoplastik Gmbh||Vorrichtung zum Auspressen von Kunststoffmassen enthaltenden Kartuschen|
|DE102014111035A1 *||Aug 4, 2014||Feb 4, 2016||Aap Biomaterials Gmbh||Mischvorrichtung, insbesondere ausgebildet zum Mischen von Knochenzement|
|EP0087029A1 *||Feb 4, 1983||Aug 31, 1983||Hans Klaus Schneider||Device for mixing dental masses|
|EP0319639A1 *||Apr 19, 1988||Jun 14, 1989||Lawrence Dr. Colin||Dispensing mixer for the storage and mixing of separate materials|
|EP0492412A1 *||Dec 18, 1991||Jul 1, 1992||THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte||Dynamic mixer|
|EP0492413A1 *||Dec 18, 1991||Jul 1, 1992||THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte||Device for mixing and applying masses composed of several components|
|EP0603492A1 *||Oct 22, 1993||Jun 29, 1994||Franz-Josef Dr. Bergmann||Device for mixing and distributing pasty substances|
|EP0710487A2 *||Nov 1, 1995||May 8, 1996||Eli Lilly And Company||Manifold for injection apparatus|
|EP0723807A2 *||Aug 24, 1995||Jul 31, 1996||Wilhelm A. Keller||Mixer and multiple component dispensing device assembly and method for the aligned connection of the mixer to the multiple component dispensing device|
|EP0880372A1 *||Feb 3, 1997||Dec 2, 1998||Plasmaseal Corporation||Method and apparatus for applying tissue sealant|
|EP1083962A1 *||Jun 2, 1999||Mar 21, 2001||Baxter International Inc.||Direct dual filling device for sealing agents|
|EP1488758A1 *||Jun 18, 2003||Dec 22, 2004||3M Espe Ag||Dispensing cartridge|
|EP1550512A2 *||Nov 22, 2004||Jul 6, 2005||Mixpac Systems AG||Fluid applying device for a fluid dispensing apparatus|
|EP1985358A1 *||Apr 23, 2008||Oct 29, 2008||Tyco Healthcare Group, LP||Applicator system and method of use|
|EP2102076A1 *||Dec 14, 2007||Sep 23, 2009||3M Innovative Properties Company||Mixing and dispensing curable multi-component materials|
|EP2111801A1 *||Apr 21, 2009||Oct 28, 2009||Tyco Healthcare Group LP||Dynamic mixing applicator|
|EP2236088A1||Mar 29, 2010||Oct 6, 2010||Confluent Surgical Inc.||Compartmented syringe|
|EP2275039A1||Mar 2, 2001||Jan 19, 2011||NeoMend, Inc.||Dispenser for an adhesive tissue sealant|
|EP2364771A1||Apr 23, 2008||Sep 14, 2011||Tyco Healthcare Group LP||Applicator system and method of use|
|WO1983002712A1 *||Feb 4, 1983||Aug 18, 1983||Hans Klaus Schneider||Device for blending dental pastes|
|WO1990001959A1 *||Aug 14, 1989||Mar 8, 1990||Corus Medical Corporation||Fibrinogen dispensing kit|
|WO1991002593A1 *||Aug 15, 1990||Mar 7, 1991||Sealant Equipment & Engineering, Inc.||Disposable mixing chamber liner and paddle for a dynamic mixing and dispensing gun|
|WO1997028834A1 *||Feb 3, 1997||Aug 14, 1997||Plasmaseal Llc||Method and apparatus for applying tissue sealant|
|WO1998050302A1 *||May 6, 1998||Nov 12, 1998||The Plastek Group||Product dispenser having separable refill cartridge|
|WO1999020328A2||Oct 22, 1998||Apr 29, 1999||Minnesota Mining And Manufacturing Company||Dispenser for an adhesive tissue sealant|
|WO1999020328A3 *||Oct 22, 1998||Apr 6, 2000||Minnesota Mining & Mfg||Dispenser for an adhesive tissue sealant|
|WO2000021653A1 *||Oct 14, 1999||Apr 20, 2000||Kettenbach Gmbh & Co. Kg||Device for applying a pasty two-component mixture|
|WO2001024869A1 *||Oct 6, 1999||Apr 12, 2001||United States Surgical||Fibrin sealant applicator system|
|WO2001062333A1 *||Feb 23, 2001||Aug 30, 2001||United States Surgical, A Division Of Tyco Healthcare Group||Adhesive applicator|
|WO2001067961A1 *||Mar 2, 2001||Sep 20, 2001||3M Innovative Properties Company||Dispenser for an adhesive tissue sealant|
|WO2004030729A1 *||Sep 24, 2003||Apr 15, 2004||Bausch & Lomb Incorporated||Double-barrel syringe for ophthalmic surgeries|
|WO2004047969A1 *||Nov 13, 2003||Jun 10, 2004||Chemische Fabrik Kreussler & Co. Gmbh||Device for producing medical foam|
|WO2004056281A1 *||Dec 19, 2003||Jul 8, 2004||Ernst Mühlbauer Gmbh & Co. Kg||Device for dispensing a mixed multi-component compound|
|WO2004071329A1 *||Feb 11, 2004||Aug 26, 2004||Tchouangang Lydie||Kit which is used to take individual human or animal dental impressions|
|WO2007109915A1 *||Mar 23, 2007||Oct 4, 2007||Medmix Systems Ag||Discharge arrangement with detachably fastenable accessory parts|
|WO2008091251A2 *||Jan 23, 2007||Jul 31, 2008||Infusive Technologies, Llc||Mixing syringe with and without flush|
|WO2011006056A1 *||Jul 9, 2010||Jan 13, 2011||Ams Research Corporation||Multi-chamber cellular mixing and delivery system and method|
|WO2015077456A3 *||Nov 20, 2014||Nov 19, 2015||Tapocik Bryan||Pen removably retaining single use capsule|
|WO2016152527A1 *||Mar 9, 2016||Sep 29, 2016||株式会社ジーシー||Double syringe|
|U.S. Classification||222/82, 604/82, 222/145.6, 222/137, 604/191, 222/327|
|International Classification||B05C17/01, B01F15/00, B05C17/005, A61C9/00, B01F13/00|
|Cooperative Classification||B05C17/00566, B05C17/00513, A61C5/064, B05C17/00593, B01F15/00487, B01F15/00519, B01F13/002, A61C9/0026, B01F2215/0039|
|European Classification||B01F13/00K2B, B01F15/00L8D, B05C17/005X, A61C5/06A2, B05C17/005F6, A61C9/00C|