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Publication numberUS3769490 A
Publication typeGrant
Publication dateOct 30, 1973
Filing dateMar 27, 1972
Priority dateMar 27, 1972
Publication numberUS 3769490 A, US 3769490A, US-A-3769490, US3769490 A, US3769490A
InventorsCzaplinski T
Original AssigneeSquibb & Sons Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Transparent storage container for tc-99m eluate
US 3769490 A
Abstract
A storage vessel for a reaction vial containing Tc-99m eluate comprises either a transparent leaded glass vessel having a thickness of from about 0.3 cm to about 2.5 cm and a lead content of from about 30 percent to about 65 percent by weight or an inner transparent receptacle which fits into an outer transparent container, the space between the inner and outer containers being filled with an aqueous, substantially saturated solution of lead perchlorate. A syringe for injecting Tc-99m eluate into a patient is formed of leaded glass as above.
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Description  (OCR text may contain errors)

zifraii btie i rim v 7 V, r Umted Stat; [111 3,769,490 Czaplinski Oct. 30, 1973 [54] TRANSPARENT STORAGE CONTAINER 2,223,118 11/1940 Miller 250/108 WS FOR 99 ELUATE 3,655,985 4/1972 Brown et al 250/108 WS X [75] Inventor: Thomas V. Czaplinski, North Brunswick, NJ

[73] Assignee: E. R. Squibb & Sons, Inc.,

Princeton, NJ.

Primary Examiner-Archie R. Borchelt AttorneyLawrence S. Levinson et al.

57 ABSTRACT [22] Filed: Mar. 27, 1972 A storage vessel for a reaction vial containing Tc-99m 1 1 pp N05 8,140 eluate comprises either a transparent leaded glass vessel having a thickness of from about 0.3 cm to about [52] U5. CL. 250/108 ws 250/106 R 250/108 R 2.5 cm and a lead content of from about 30 percent to 51 int. Cl. .3 621i 5/00 65 Percent by weight inner "amparem [58] Field of Search 250/108 R, 108 ws; ceptacle which fits into an Outer transparent on- 252 m R 106 S 108 R 108 ws tainer, the space between the inner and outer containers being filled with an aqueous, substantially satu- [56] References Cited rated solution of lead perchlorate. A syringe for inject- UNITED STATES PATENTS ing Tc-99m eluate into a patient is formed of leaded glass as above. 3,673,411 6/1972 Glasser... 250/108 R 3,286,095 11/1966 Lane 250/108 WS 5 Claims, 3 Drawing Figures TRANSPARENT STORAGE CONTAINER FOR TC-99M ELUATE BACKGROUND OF THE INVENTION The present day use of the field of medicine of radioactive diagnostic kits requires that the vessel containing the radioactive substance be shielded to reduce radiation exposure to personnel administering the radioactive diagnostic test to the patient. For example, an aliquot of an eluate from a Tc-99m generator that contains from about 1 to about 100 millicuries of Tc-99m is used to prepare a radioactive formulation in a reaction vial from which it is withdrawn into a syringe for injection into the patient. While it is desirable to be able to observe the product during preparation, it has not been possible heretofore to permit this due to the necessity of providing lead shielding around both the reaction vial and the syringe. The eluate remaining in the reaction vial is then stored in' a lead container which does not permit visual observation of the amount of eluate remaining. Even when the syringe shielding and the lead container are provided (at great cost) with glass windows, it is still not possible to observe the eluate clearly.

OBJECTS OF THE INVENTION It is,'accordingly, an object of the present invention to provide a storage vessel for a reaction vial containing radioactive material, which storage vessel, while transparent, nevertheless provides protection against exposure to radiation. Another object is to provide a syringe which, while transparent, nevertheless provides protection against exposure to radiation. These and other objects of the present invention will be apparent from the following description.

BRIEF DESCRIPTION OF THE DRAWING FIG. 1 is an elevational view of one embodiment of a storage vessel, partially in section; and

FIG. 2 is an elevational view of another embodiment of a storage vessel, partially in section; and

FIG. 3 is a plan view of a syringe.

DETAILED DESCRIPTION Referring to the drawings, FIG. 1 shows a storage container formed of an inner, substantially beakershaped container which is formed of glass or transparent plastic, and an outer substantially beakershaped container 11 also formed of glass or transparent plastic. The inner and outer containers are spaced apart a distance of from about 0.6 cm to about 2.5 cm and the intervening space is filled with a substantially saturated solution of lead perchlorate 12. Inner container 10 has top flange 13 which rests on the rim 14 of outer container 11. In use the reaction vial (not shown) is placed in inner container 10 and a lead cap 15 placed on the top. Cap 15 and lead perchlorate solu tion 12 provide protection against radiation.

FIG. 2 shows another substantially beaker-shaped storage container 20 formed of solid, transparent leaded glass having a wall thickness of from about 0.3 cm to about 2.5 cm, preferably from about 0.6 cm to about l.2 cm, and a lead content of from about 30 percent to about 65 percent by weight. Generally, a higher lead content will be associated with a thinner wall. Once the reaction vial (not shown) is placed in container 20, a lead cap 21 is placed over the container.

If desired, the cap in either of the above storage containers may be formed of leaded glass in which event the entire container including the cap is transparent.

FIG. 3 is a plan view of a syringe which is otherwise conventional but which is formed of transparent leaded glass barrel 40 having a wall thickness of from about 0.6 cm to about 1.2 cm, and a lead content of from about 30 percent to about 65 percent. Generally, a higher lead content is employed with a thinner wall syringe.

What is claimed is:

1. A storage container for a vessel housing radioactive eluate comprising an entirely transparent outer container shell including side and bottom walls, an entirely transparent cover memberrseated on the rim of the outer container side walls, said cover member including a central depression defining a radioactive material receiving cavity, said cavity being spaced from the interior walls of the outer shell defining a continu ous compartment therebetween, said compartment being filled with transparent radioactive shielding material.

2. The container recited in claim 1 including a cap member sealing the tops of said depression and said outer shell which cap member extends across the rim of said outer shell and across said depression, said cap member being crimped about the exterior side walls of said outer shell, and said cap member is fabricated from radioactive shielding material.

3. The container of claim 1 wherein said radioactive shielding material is a solution of substantially saturated lead perchlorate.

4. The storage container of claim 1 wherein said cover and said outer shell are fabricated from glass having a wall thickness of 0.3 cm to 2.5 cm and a lead content of from 30 percent to 65 percent by weight.

5. The storage container of claim 1 wherein said cover and said outer shell are fabricated from a transparent plastic.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2223118 *Mar 25, 1938Nov 26, 1940Pittsburgh Plate Glass CoAbsorptive glass
US3286095 *Sep 30, 1963Nov 15, 1966Lane William BZinc bromide radiation-shielding window maintained under an inert gas atmosphere
US3655985 *May 20, 1969Apr 11, 1972Mallinckrodt Chemical WorksRadiation-shielding receptacle for a bottle for receiving a radioactive eluate
US3673411 *Mar 3, 1970Jun 27, 1972Nuclear Associates IncHolder for radioactive material
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3973554 *Apr 24, 1975Aug 10, 1976The United States Of America As Represented By The Secretary Of The Department Of Health, Education And WelfareRadiation safety shield for a syringe
US4022317 *Jul 7, 1975May 10, 1977Kms Fusion, Inc.Package for fragile objects
US4122836 *Sep 13, 1976Oct 31, 1978Nuclear Pacific, Inc.Shielding holder for radionuclid syringes
US4185619 *Dec 1, 1975Jan 29, 1980Atomic Products CorporationRetractable shield for syringes
US4270052 *Jun 18, 1979May 26, 1981King Russell WRadioactive gas dose computer
US4466426 *Jun 13, 1983Aug 21, 1984Blackman Seymour NSyringe with actinic ray blocking stripe
US5552612 *Dec 22, 1994Sep 3, 1996Nihon Medi-Physics Co., Ltd.Transport container for transporting radiation shield member
US6166284 *Nov 25, 1998Dec 26, 2000Mds Nordion Inc.Container for radioisotopes
US7842023Feb 3, 2003Nov 30, 2010Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
US8292869Jul 14, 2010Oct 23, 2012Sigma-Tau Industrie Farmaceutiche Riunite SpaContainer for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
EP0091175A1 *Apr 5, 1983Oct 12, 1983Machiel Nicolaas DuivelaarMethod for the safe storage of dangerous materials endangering persons and/or the environment, and appropriate shielding casing
WO2003069632A2Feb 3, 2003Aug 21, 2003Marco ChinolContainer for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
Classifications
U.S. Classification250/432.00R, 250/506.1, 600/5, 976/DIG.350
International ClassificationG21F5/015, G21F5/00
Cooperative ClassificationG21F5/015
European ClassificationG21F5/015