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Publication numberUS3807119 A
Publication typeGrant
Publication dateApr 30, 1974
Filing dateJun 21, 1972
Priority dateJun 21, 1972
Publication numberUS 3807119 A, US 3807119A, US-A-3807119, US3807119 A, US3807119A
InventorsW Shields
Original AssigneeW Shields
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Method of assembling a multiple compartment hypodermic syringe
US 3807119 A
Abstract
A liquid containing syringe barrel is first fully assembled including a valve in the discharge portion of the barrel, liquid above the valve, a plunger above the liquid, a plunger rod attached to the plunger and a piston cap on the discharge end of the liquid syringe barrel, and subsequently a second syringe barrel is engaged over the discharge end portion of the liquid containing syringe barrel, the piston cap retaining the second syringe barrel on the first or liquid containing syringe barrel. Said assembly of the two syringe barrels is then inverted to permit the filling of powder into the second syringe barrel which is subsequently capped and provided with a sheathed hypodermic syringe needle.
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United States Patent [1 1 Shields [451 Apr. 30, 1974 METHOD OF ASSEMBLING A MULTIPLE COMPARTMENT HYPODERMIC SYRINGE Inventor: Walter A. Shields, Jamaica, NY.

Filed: June 21, 1972 Appl. No.: 264,960

US. Cl 53/22 R, 29/208 B, 128/218 M, 128/220 Int. Cl B65b 3/06, B65b 29/10 Field of Search 53/22 R, 37, 43; 29/208 B; 128/220, 218 M References Cited UNITED STATES PATENTS Primary ExaminerDonald R. Schran ABSIRACT A liquid containing syringe barrel is first fully assembled including a valve in the discharge portion of the barrel, liquid above the valve, a plunger above the liquid, a plunger rod attached to the plunger and a piston cap on the discharge end of the liquid syringe barrel, and subsequently a second syringe barrel is engaged over the discharge end portion of the liquid containing syringe barrel, the piston cap retaining the second syringe barrel on the first or liquid containing syringe barrel. Said assembly of the two syringe barrels is then inverted to permit the filling of powder into the second syringe barrel which is subsequently capped and provided with a sheathed hypodermic syringe needle.

8 Claims, 19 Drawing Figures :RATENTEDAPR 30 ISM 3807-119 sum 3 ur 3 ringe barrel is conveyed to a second assembling station where a measured quantity of liquid is delivered through the open end of the first syringe barrel above I the valve.' From the liquid delivering station, the first syringe barrel is conveyed to a third assembling station where a plunger is inserted through the open end into the first syringe barrel to sealthe liquid in said syringe barrel. From the third assembling station, the first syringe barrel 'is conveyed to'a fourthassembling station wherea plunger rod is'attached to the plungerfwitha manipulating'portion of the plunger rod extended exteriorly from the first syringe barrel through the open end 2' site ends'of said body 10 arranged with liquid-sealing rings 13 to tightly and slidably engage the bore of the syringe barrel The valves v are delivered from a hopper 14 to the vibratory feeder 8 and the mechanism 9.

After the valve v isins erted in the syringe barrel 5, said syringe barrel is advanced by the vibratory feeder 8 to a filling device 15, at station C, which will delivery a measured quantity of liquid 1', such as a solvent, to the syringe barrel against the valve v having the slit l2 closed by the resiliency of the material of saidvalve.

, After the syringe barrel 5 received its measured quantityof liquid 1, the syringe barrelS is conveyed by the vibratory feeder 8 to station D where plungers p are delivered from a hopper 16 to the. vibratory, feeder 8 relative to apparatus 17 for inserting a plunger p into the syringe barrel 5 through the open end 6 into proximity with the liquid 1 to seal'said liquid 1 in the syringe barrel 5; As shown in FIG. 4, the plunger p comprises thereof. At the succeeding fifth assembling station, a

piston cap is engaged over the neck portion of the first syringe barrel and at the succeeding sixth assembling station, a second syringe barrel 'is positioned in vertical spaced alignment below the capped neck portion of the first syringe barrel. At the seventh assembling station, the second syringe barrel is moved over the first syringe barrel with the piston cap retaining the second syringe barrel on the firstsyringe barrel. At the eight assembling station, the assembled first and second syringe barrels are inverted and in said inverted position they are conveyed toa ninth as'semblingstation where powder is delivered to the second syringe barrel through a neck portion of said second syringe. barrel and against the capped neck portion of the first syringe barrel. At

tion. Finally at thetwelfth and thirteenth assembling stations; a hypodermic needle carrying cap is successively positioned over the 'pierceable cap and spun to the neck portion of the second syringe barrel.

In the drawings accompanyingand forming apart of this application: I

FIGS.- 1A to 1N, inclusive, show the successive steps of assembling a multiple compartment hypodermi y e byrs zgwin h .el mentsiuve y d;

FIG. 2 is a diagrammaticplan view of the devices for performing the steps of the-present invention;

FIG. 3 is a vertical-sectional view of a valve;

FIG. 4 is a vertical-sectional view of a plunger;

FIG. 5 is a view of a plunger rod; and

FIG. 6 is a vertical-sectional view of a piston cap.

In carrying out the method ofassembling a multiple compartment hypodermic syringe, there are provided devices or apparatus shown in FIG; 2 as comprising a hopper 4 fora plurality of first syringe barrels 5 having an open filler end 6 and a discharge neckportion 7. The syringe barrels 5 are delivered in a vertical position with the neck portion 7 lowermost to a vibratory feeder 8 conveying said syringe barrels 5 fromstation A to station B where valves v of resilient material, such as rub her, are inserted into the syringe barrels 5 by mechanism 9 to abut the neck portion 7. As shown in FIG. 3, the 'valve comprises a tubular body 10 closed by a transverse wall 11 provided with a slit 12 and the oppoa rubber plug 1'8lhaving a recess 19 in the upper end and'liquid-sealing rings 20 to slid-ably engage the bore of the syringe barrel 5.

From station D, the syringe barrel 5 is conveyed by the vibratory feeder 8 to station E where plunger rods r are delivered from a hopper 21 to a device 22 to insert a plunger rod rinto the recess 19 of the rubber plug 18. As shown in FIG. 5,:said plunger rods r comprise a rod 23 having a reduced. screw-threaded end 24 to be threaded into the recess 19 and a knob 25 at the oppo site erid which ispositioned exteriorly of the open end The syringe barrel 5 is then conveyed from station E to station F by the vibratory feeder 8 and a rotating table 23 to receive a piston cap 24 of resiliant material, such as rubber, having the closed end or bottom provided with a pair of holes 25 on diametrically/opposite sides of aprotuberance26to plug up the opening in the neck portion 7 and sealing rings 27, as shown in FIG. 6. The caps 24 arede'livered from a hopper 28 by a chute 29to the syringe barrel 5 on the rotating table 23 at station F..

The completely assembledsyringe barrel 5 is conveyed by the'rot'ating table 23 'from station F to station G where a second syringe barrel 30is positioned in vertical spaced alignment below theneck portion 7 by a chute 31' delivering saidsyringe barrels 30 from a hopper 32. The stringe barrels 30'have'a bore to snugly fit the sealing rings 27 of the caps 24. The syringe barrel 30 is provided with an open end 33 and a neck portion 34 at the opposite end, and the syringe barrels 30 are delivered and positioned in vertical spaced alignment with the syringe barrel 5with' the open end 33 uppermost.

I The syringe barrels5 and 30 are conveyed in vertical spaced alignment with each other by the rotating table 23 from station G to station H, where the syringe barrel 30- is moved 'onto the syringe barrel 5 to a predetermined distance toprovide a space between the cap 24 and the neck 'portion'34. The sealing rings 27 will retain thesyringe barrel 30 'on the syringe barrel 5.

The connected syringe barrels 5 and 30 are conveyed by the rotatingtable 23 from station H to station I where said connected syringe barrels 5 and 30 are inverted and delivered to a vibratory feeder 35 which conveys the inverted syringe barrels 5 and 30 to a rotating table 36 which conveys said inverted syringe barrels 5 and 30 to a filling device 37 at station J where medicament m in powder form is delivered to the syringe barrel 30 through the neck portion 34. The amount of powder delivered is limited by the space in the syringe barrel 30 between the cap 24 and the neck portion 34.

From station J, the assembled or connected syringe barrels and 30 are conveyed by the rotating table 36 and rotating tables 38 and 39 to station K where a pierceable closure cap 40 is positioned on the neck portion 34 at the delivery end of a chute 41 receiving said pierceable closure caps 40 from a hopper 42.

From station K, the assembled syringe barrels 5 and v 30 are conveyed by the rotating table 39 to station L From station M, the vibratory feeder 44 conveys the assembled syringe barrels 5 and 30 to station N where a spining device 49 secures the mounting cap 47 to the neck portion 34.

From station N, the vibratory feeder 44 delivers the fully assembled multiple compartment hypodermic syringe to a suitable depository, not shown.

Having thus described my invention, I claim:

1. Method of assembling a multiple compartment hypodermic syringe which comprises providing a first syringe barrel open at one end and having a neck portion at the opposite end, inserting a valve into the first syringe barrel through the open end thereof and against the neck portion of the first syringe barrel, delivering a measured quantity of liquid to the first syringe barrel through the open end thereof, inserting a plunger into the first syringe barrel through the open end thereof to retain the liquid in the first syringe barrel, connecting a plunger rod to the plunger through the open end of 4 the first syringe barrel, and applying a piston cap to the neck portion.

2. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 1, providing a second empty syringe barrel open at one end and having a neck portion at the opposite end and having a bore of a diameter to form a tight sliding fit with the piston cap on the-neck portion of the first syringe barrel, positioning said second syringe barrel in vertical spaced alignment below the first syringe barrel with the neck portion of the second syringebarrel lowermost, and raising the second syringe barrel onto the first syringe barrel with the piston cap of the first syringe barrel spaced from the neck portion of the second syringe barrel and retaining the second syringe barrel on the first syringe barrel. I

3. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 2, reversing the vertical positions of the first and second syringe barrels with the second syringe barrel uppermost.

4. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 3, filling the second syringe barrel with powder through the neck portion thereof.

5. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 4, positioning a pierceable closure cap on the neck portion of the second syringe barrel. 1

6. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 5, securing said pierceable closure cap to the neck portion of the second syringe barrel.

7. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 6, positioning an assembled sheathed hypodermic needle and mounting cap on the pierceable closure cap secured to the neck portion of the second syringe barrel.

8. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 7, securing the mounting cap to the neck portion of the second syringe barrel.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US3557787 *May 28, 1968Jan 26, 1971Milton J CohenDisposable syringe
US3678931 *Jun 9, 1970Jul 25, 1972Milton J CohenSyringe
US3708945 *Jan 6, 1971Jan 9, 1973Upjohn CoSyringe assembling method and machine
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US4729875 *Jun 26, 1986Mar 8, 1988Allelix Inc.Device for performing immunochemical assays
US5522804 *Apr 22, 1994Jun 4, 1996Lynn; Lawrence A.Aspiration, mixing, and injection syringe
US5549569 *Mar 30, 1995Aug 27, 1996Lawrence A. LynnEx vivo blood isolation system
US5586975 *Dec 29, 1994Dec 24, 1996Takeda Chemical Industries. Ltd.Air and liquid tight container with a slidable gasket
US5605542 *Nov 14, 1995Feb 25, 1997Takeda Chemical Industries, Ltd.Prefilled syringe
US5643218 *Aug 20, 1996Jul 1, 1997Lawrence A. LynnAuto-flushing medical fluid injection system
US5697915 *May 30, 1996Dec 16, 1997Lynn; Lawrence A.Displacement-activated medical check valve
US5716339 *Sep 19, 1995Feb 10, 1998Takeda Chemical Industries, Ltd.Prefilled syringe
US5743886 *Aug 20, 1996Apr 28, 1998Lawrence A. LynnSequential medical fluid aspiration and injection system and method
US5769825 *Aug 20, 1996Jun 23, 1998Lynn; Lawrence A.Self-contained syringe and pharmaceutical packaging system for enclosed mixing of pharmaceutical and diluent
US5817056 *Sep 11, 1996Oct 6, 1998Takeda Chemical Industries, Ltd.Prefilled syringe
US5865799 *Jul 23, 1997Feb 2, 1999Takeda Chemical IndustriesPrefilled syringe
US5884457 *Feb 5, 1997Mar 23, 1999Smithkline Beecham CorporationMethod and apparatus for automatically producing a plurality of sterile liquid filled delivery devices
US6065270 *Dec 18, 1997May 23, 2000Schott GlaswerkeMethod of producing a filled plastic syringe body for medical purposes
US6228065Jun 22, 1998May 8, 2001Lawrence A. LynnDisplacement activated medical check valve
US6813868Aug 10, 2001Nov 9, 2004Baxa CorporationMethod, system, and apparatus for handling, labeling, filling and capping syringes
US6915619Dec 3, 2003Jul 12, 2005Baxa CorporationMethod for handling syringe bodies
US6957522Dec 3, 2003Oct 25, 2005Baxa CorporationMethod and system for labeling syringe bodies
US6976349Jul 30, 2003Dec 20, 2005Baxa CorporationMethod for filling and capping syringes
US7207152Feb 24, 2006Apr 24, 2007Baxa CorporationMethod for handling, labeling and filling syringes
US7392638Feb 28, 2006Jul 1, 2008Baxa CorporationMethod, system, and apparatus for handling, labeling, filling, and capping syringes with improved cap
US7469518Jun 29, 2006Dec 30, 2008Baxa CorporationMethod for handling and labeling syringes
US7478513Jun 29, 2006Jan 20, 2009Baxa CorporationMethod for handling and labeling syringes
US7621887 *Oct 23, 2003Nov 24, 2009Meridian Medical Technologies, Inc.Wet/dry automatic injector assembly
US7631475May 14, 2008Dec 15, 2009Baxa CorporationMethod for filling and capping syringes
US8234769 *Sep 6, 2007Aug 7, 2012Robert Bosch GmbhDevice and method for mounting a needle guard on a syringe body
US8763350 *Jun 16, 2009Jul 1, 2014Arzneimittel Gmbh Apotheker Vetter & Co. RavensburgMethod for filling dual-chamber systems in pre-sterilizable carrier systems
US20100162548 *Sep 6, 2007Jul 1, 2010Juergen LeidigDevice and method for mounting a needle guard on a syringe body
US20100299904 *May 21, 2010Dec 2, 2010Angelo AnsaloniMethod and apparatus for screwing pistons of syringes
US20110094189 *Jun 16, 2009Apr 28, 2011Arzneimittel Gmbh Apotheker Vetter & Co. RavensburgMethod for filling dual-chamber systems in pre-sterilizable carrier systems and pre-sterilizable carrier system
US20110138749 *Dec 15, 2009Jun 16, 2011Donald ChowSystem and method for manufacturing a tubular container with opening and closing means
US20130219710 *Nov 11, 2011Aug 29, 2013Michael JuglAssembly Device for Injection Needles
Classifications
U.S. Classification53/471, 29/778, 29/777, 604/89
International ClassificationA61M5/00, A61M5/19
Cooperative ClassificationA61M5/31596, A61M2207/00, A61M2005/31598, B65B3/003, B65B7/2821
European ClassificationA61M5/315M, B65B3/00B, B65B7/28C