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Publication numberUS3810367 A
Publication typeGrant
Publication dateMay 14, 1974
Filing dateJul 16, 1970
Priority dateJul 16, 1970
Publication numberUS 3810367 A, US 3810367A, US-A-3810367, US3810367 A, US3810367A
InventorsW Peterson
Original AssigneeW Peterson
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Container for cooling, storage, and shipping of human organ for transplant
US 3810367 A
Abstract
A system of containers having an organ holding container in a compartment, the compartment having its major interior walls being a heat transfer cup, the exterior of the heat transfer cup being another compartment for holding heat absorbing material (ice and water), the two compartments surrounded by a wall and lids of a heat insulating material.
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Description  (OCR text may contain errors)

llnited States Patent '62/64; 195/104, l27, 1.7; 220/94 R,94 A; 229/43 Peterson [45] May V14, i974 i [54] CONTAINER FOR COOLING, STORAGE, 3,236,206 2/1966 willingt-r 119;62/3;457 AND SHIPPING 0F HUMAN ORGAN FOR 3,468,l36 9/1969 Swenson (i2/(14 l,5l2,945 l0/l924 Norcross 62/457- TRANSPLANT. 1,369,367 2/1921 Th6fnn6n 62/457 [76] Inventor.; william D, Peterson, 1996 E, 4675 1,721,311 7/1929 Muenchen 62/457 v South sa Lake Ctyf Utah 84117 FOREIGN PATENTS 0R APPuCATloNs [22] Filedz July 16, 1970 672,665 9/1929 France 62/457 402,889 l2/l933 Great Britain 62/457 [21] APPL No" 55512 671,497 9/1929 Frnncn 62/457 i521 U.s. C1...g.'TI1162/4s672763, 627371, 62/372, prima@ Exm,-e, wi11iam 1 Wye 62/64, 195/104,` [9S/127, l95/l.7,220/9 4 [5l] Int. Cl. F2511 3/08 [57] ABSTRACT [58] Field-of Search 62/457, 463, 371, 372,

A system of containers having an organ holding container in a compartment, the compartment having its major interior walls being a heat transfer cup, the exterior of the heat transfer cup being another 'compartn ment for holding heat absorbing material (ice and water), the two compartments surrounded by a wall and lids of a heat insulating material.

7 Claims, 3 Drawing Figures ,f ff

PATENTEDMAY 14 |914 SHE. 2 F 2 FIG DI BACKGROUND OF THE INVENTION The present invention relates -to a need for being able to transfer a kidney or other human organ from a human cadaver or donor to the recipiant which in some cases may be lmany miles away. If an organ which has been removed is not to be implanted for several hours, it is desirable that the organ'be cooled andmaintained at 32 F, the transition temperature of ice to water. It is also desirable that the organ be kept sterile in a consistant normal saline solution which could vary if ice were used in the same container with the organ. Itis desirable that an organ being removed from the donor, be placed in a sterile container, which in turn is placed in a sterile compartment; such that, when the organ container is removed from the compartment at the facility for implantation, the container is sterile and can be handled in the. operating room without fear of contamination to the room and its contents.

SUMMARY OF THE INVENTION yThe invention is a system of containers, the system having two scalable lids for two separate lcompart-l ments, the outside ywalls of the system and two lids being made of a heat insulating material, the walls between the two compartments beingmade of a heat` transferring materialor, consisting of a heat transfer cup, the two compartments being sealed from each other. One compartment of the system is for holding a container which in turn holds an organ in asaline solution for cooling, storage, and/or shipping. The other compartment of the system is for ice and water .for cooling the organ to 32 F and maintaining it at that temperature until itis to be removed for implantation.

BRIEF DESCRIPTION OF THE DRAWING media between the heattransfer cup and the liner.

DESCRIPTION OF. THE PREFERRED EMBODIMENTS The organ container system consists of basically two compartments. The upper or organ compartment houses the organ container which-is formed as a liner that hasta lid l which snaps on a cup 2. The lid Vl and cup 2 are standard plastic molded items-made of polypropylene or another material which is inert to human tissue. The human organ l3 or any other animal tissue being stored is kept submerged in a normal saline solution 4. The cup 2 and lid l are -keptsterile within the pre-sterilized organ compartment which is sealed from the outside atmosphere by anO-ring 5. The organ lid 6 is attached to the container base 7 lby threads 8. The cup 2 and lid l may be kept sterile without sterilization of the organ chamber by sealing them in a sterile container 1 9 such as a plasticA or film bag before placing them in the organ compartment.-

The ice 9 and water 10 compartment is separated from the organ compartment by a heat transfer cup ll made of a heat conducting material such as aluminum. The container base 7 is molded about, bonded to, and supports the heat transfer cup 1 1. Thev heat transfer cup t 1 l has an integral inverted cup l2 such that ice 9 floating on the water l0 is kept against the heat transfer wall or cup 1 ll bottom. The ice 9 and water 10 compartment is sealed from the outside atmosphere by an O-ring 13 and is accessible by removal of a lid 14 which is held in place by threads 15.

The lids 6 and 14 and base section 7- are made of polyurethane or another heat-insulating material with similar properties. The ice and water compartment lid 14 has integrally molded feet 16 consisting of a circular ring which provides additional insulation in that it creates an airpocket between itself and the floor it is seton. The organ compartment lid 6 has an integrally molded handle 17 for carrying the system and also has feet 18 to support the system when inverted for access to the ice 9 and water 10 chamber by removal of lid I4.

solution being kept sterile within a sealed and removable organ and saline holding compartment, said sealed compartment having common heat conducting walls to a heat controlling media containing compartment, said heat controlling media being a solution of ice and water to control the temperature of the saline to its temperature by heat transfer to and from the saline, said heat controlling media containing compartment having a lid opening for access to service the media, and said removable organ and saline holding compartment having a lid opening for access to service the saline and to place in and remove said organ.-

2. Container according to claim l with the addition of a sterile container surrounding the removable organ and saline holding compartment and interposed between it and the heat controlling media, said sterile container for keeping the exterior walls of the removable organ and saline 'holding compartment sterile.

3. A controlled temperature container comprising of a housing divided into two compartments separated by a heat-transferring cup-like member, one of said compartments being adapted to hold an animal organ and the other of said compartments adapted'to hold a heat absorbing material, said cup being lined with a removableV liner material inert to animal tissue and having an additional vsterile container surrounding the liner and interposed between it and the cup, having a pair of detachable lids, a first lid on said housing for opening and closing access to oneof said compartments anda second lid of saidl housing for opening and closing access to said other compartment.

4. A controlled temperature container comprising of a housing divided into two compartments separated by a heat-transferring cup-like member, one ,of said compartments being adapted to hold an animal organ and the other of said compartments adapted to hold a heat absorbing material, having a pair of detachable lids, a

first lid on said housing for opening and closing access to one of said compartments and a second lid of said housing for opening and closing access to said other compartment, said lids having feet on their exterior enabling the standing of the container on either end, and in which the feet of at least one of said lids are formed as a handle for carrying the container.

S. Container according to claim 4 with the addition of threads on the container base and lids, for holding the lids on and in place.

6. A controlled temperature container comprising of a housing divided into two compartments separated by a heat-transferring cup-like member, one of said compartments being adapted to hold an animal organ and the other of said compartments adapted to hold a heat absorbing material, said cup being lined with a removable liner material inert to animal tissue, having a fluid such as water between the heat transfer cup and the liner to improve the heat flow from the organ to the heat absorbing material, having a pair of detachable lids, a first lid on said housing for opening and closing access to one of said compartments and a second lid of said housing for opening and closing access to said other compartment.

7. A controlled temperature container comprising of two compartments separated by a heat-transferring member, one of said compartments being adapted to hold an animal organ and the other of vsaid compartment adapted to hold a heat absorbing material, said animal organ holding compartment being lined with a removable liner material inert to animal tissue, and having an additional sterile container surrounding the liner and interposed between it and the heattransferring member.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1369367 *Jan 5, 1920Feb 22, 1921Henry M WhitneyCooling-container
US1512945 *Mar 12, 1924Oct 28, 1924Norcross Crandall UShipping receptacle
US1721311 *Sep 28, 1925Jul 16, 1929Arctic Refrigeration Mfg CorpRefrigerating vessel
US2662520 *Feb 6, 1951Dec 15, 1953Little Inc APreservation and storage of biological materials
US3006165 *Oct 31, 1956Oct 31, 1961Masson Paul IncContainers
US3027734 *Mar 18, 1960Apr 3, 1962Reflectotherm IncChilling and freezing systems
US3205677 *Dec 17, 1962Sep 14, 1965Arthur M StonerPortable device for cooling drinking glasses and the like and their contents
US3236206 *Jan 3, 1964Feb 22, 1966Aquariums IncPackage for shipping tropical fish
US3468136 *Jul 16, 1968Sep 23, 1969Swenson Emil SMethod for maintaining organs in a completely viable state
FR671497A * Title not available
FR672665A * Title not available
GB402889A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3995444 *Nov 8, 1974Dec 7, 1976American Hospital Supply CorporationOrgan perfusion system
US4042142 *Apr 30, 1976Aug 16, 1977Ruano Robert WBeer keg cooling container
US4145895 *Jan 6, 1977Mar 27, 1979Hjertstrand Ake WApparatus for storing goods at stable temperatures in a heat-insulated container
US4217890 *Nov 3, 1978Aug 19, 1980Owens Milton LSurgical sling for positioning a harvested kidney during surgical reattachment
US4242883 *Apr 2, 1979Jan 6, 1981Henry Ford HospitalLiver preservation
US4262494 *Jan 30, 1980Apr 21, 1981Karow Jr Armand MPortable device for cryopreservation, transportation and temporary cryogenic storage of semen and other similar tissue
US4322954 *Jun 11, 1981Apr 6, 1982Sheehan Laurence MPortable cooler for medicine
US4473637 *Nov 10, 1982Sep 25, 1984Guibert, Colman & AssociatesApparatus for flushing, cooling
US4502295 *Feb 21, 1984Mar 5, 1985Mount Carmel Research And Education CorporationOrgan hypothermic storage unit
US4530816 *Jun 15, 1983Jul 23, 1985Hamilton FarmVeterniary medicine; equine semen and embryos
US4723974 *Aug 27, 1986Feb 9, 1988Ammerman Stephen WPlurality of cooling bags containing pair of substances that produce even distribution of cooling when mixed
US4739626 *Apr 6, 1987Apr 26, 1988Titomir DjelicCool-air cooling box for motor vehicles
US4745759 *Dec 23, 1986May 24, 1988Bauer Dan OKidney preservation machine
US4862674 *Oct 23, 1987Sep 5, 1989Lejondahl Lars ErikThermally insulated container
US4878363 *Feb 15, 1989Nov 7, 1989Wells Sr Francis ESuper kooler
US4951482 *Dec 21, 1988Aug 28, 1990Gilbert Gary LHypothermic organ transport apparatus
US4955480 *Jul 21, 1989Sep 11, 1990Sexton Wilson CPortable insulated carrier
US5171660 *Apr 26, 1989Dec 15, 1992Cryolife, Inc.Process of revitalizing cells and tissue prior to cryopreservation
US5236088 *Jul 29, 1992Aug 17, 1993Smith & Nephew Richards, Inc.Biomedical material shipment kit and method
US5295365 *Oct 27, 1992Mar 22, 1994Redford Thomas AInvertible cooler
US5355684 *Apr 30, 1992Oct 18, 1994Guice Walter LCryogenic shipment or storage system for biological materials
US5424207 *Aug 10, 1992Jun 13, 1995Cryolife, Inc.Preincubation
US5434045 *May 8, 1992Jul 18, 1995Jost Leonora IBiological support system container
US5435142 *Sep 30, 1994Jul 25, 1995In Vitro Technologies, Inc.Method of and apparatus for packaging temperature sensitive materials for transportation
US5586438 *Mar 27, 1995Dec 24, 1996Organ, Inc.Portable device for preserving organs by static storage or perfusion
US5983661 *Nov 27, 1998Nov 16, 1999Wiesman; Jon P.Container arrangement and method for transporting equine semen
US6230515Aug 6, 1999May 15, 2001Jon P. WiesmanContainer arrangement and method for transporting equine semen
US6238907Feb 26, 1999May 29, 2001Doris Schuler-MaloneyVessels for accurate evaluation of biological tissues
US6506205Feb 20, 2001Jan 14, 2003Mark GoldbergBlood clot filtering system
US6673594Aug 25, 2000Jan 6, 2004Organ Recovery SystemsPortable hermetically-sealed housing configured to be received by organ perfusion device
US6736836Feb 16, 2001May 18, 2004The Johns Hopkins UniversityTransplant organ external cooling system
US6918922Jan 28, 2003Jul 19, 2005Amir OronIschemia laser treatment
US7176015Oct 23, 2003Feb 13, 2007Organ Transport Systems, Inc.Using cooled, oxygenated nutrient solution; flexible permeable tube, electric pump
US7303578Oct 9, 2003Dec 4, 2007Photothera, Inc.Device and method for providing phototherapy to the brain
US7309348Jan 19, 2005Dec 18, 2007Photothera, Inc.Method for treatment of depression
US7316922Jan 8, 2003Jan 8, 2008Photothera Inc.Method for preserving organs for transplant
US7534255Jan 26, 2004May 19, 2009Photothera, IncLow level light therapy for enhancement of neurologic function
US7575589Mar 21, 2006Aug 18, 2009Photothera, Inc.Light-emitting device and method for providing phototherapy to the brain
US7678563Apr 2, 2004Mar 16, 2010Organ Recovery Systems, Inc.Organ perfusion device for monitoring, sustaining and/or restoring viability of organs and for the preserve of organs for storage and/or transport
US7691622Apr 2, 2004Apr 6, 2010Lifeline Scientific, Inc.Method and apparatus for transferring heat to or from an organ or tissue container
US7695504Jan 7, 2008Apr 13, 2010The United States Of America As Represented By The Department Of Health And Human ServicesMethod for regeneration and functional recovery after spinal cord injury using phototherapy
US7721566Feb 6, 2007May 25, 2010Minnesota Thermal Science, LlcCollapsible interconnected panels of phase change material
US7749693Feb 2, 2004Jul 6, 2010Lifeline Scientific, Inc.Perfusing organ with immunotoxin and monitoring effects; sustaining and/or restoring viability of organs and preserving organs for storage and/or transport
US7824848Jul 11, 2003Nov 2, 2010Lifeline Scientific, Inc.Organ perfusion device for sustaining, restoring viability, storage, transport and preservation of tissues
US7848035Sep 18, 2008Dec 7, 2010Photothera, Inc.Single-use lens assembly
US7998725Apr 2, 2004Aug 16, 2011Organ Recovery SystemsMethod and apparatus for holding a plurality of tubes connectible to an organ or tissue container
US8025687May 4, 2009Sep 27, 2011Photothera, Inc.Low level light therapy for enhancement of neurologic function
US8097449Feb 16, 2010Jan 17, 2012Organ Recovery SystemsMethod and apparatus for transferring heat to or from an organ or tissue container
US8128740Apr 2, 2004Mar 6, 2012Organ Recovery Systems, Inc.Device for separating gas from a liquid path
US8149526Nov 2, 2010Apr 3, 2012Photothera, Inc.Single use lens assembly
US8167921Jun 20, 2011May 1, 2012Jackson StreeterLow level light therapy for enhancement of neurologic function
US8268547Oct 25, 2005Sep 18, 2012Lifeline Scientific, Inc.Method of transporting and storing a kidney
US8268612Aug 10, 2011Sep 18, 2012Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8308784Aug 23, 2007Nov 13, 2012Jackson StreeterLow level light therapy for enhancement of neurologic function of a patient affected by Parkinson's disease
US8318415Oct 22, 2010Nov 27, 2012Lifeline Scientific, Inc.Method of determining transport and/or storage parameters for maintaining viability of an organ
US8323954Mar 29, 2011Dec 4, 2012Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8328857Feb 25, 2010Dec 11, 2012The United States Of America As Represented By The Department Of Health And Human ServicesMethod for treating a patient having a spinal cord injury using phototherapy
US8349551Nov 5, 2010Jan 8, 2013Lifeline Scientific, Inc.Method for controlling perfusion of an organ
US8361091Aug 25, 2003Jan 29, 2013Organ Recovery Systems, Inc.Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US8365941 *May 15, 2009Feb 5, 2013David James MayerDual-capped hydration bottle
US8389271Dec 31, 2009Mar 5, 2013Organ Recovery Systems, Inc.Method and apparatus for controlling air pressure in an organ or tissue container
US8420381Nov 5, 2010Apr 16, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8424335Dec 17, 2009Apr 23, 2013Minnesota Thermal Science, LlcCascading series of thermally insulated passive temperature controlled containers
US8431385Jan 21, 2011Apr 30, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8444666Sep 12, 2003May 21, 2013Cook Medical Technologies LlcRetrievable filter
US8445260Aug 10, 2011May 21, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US8609400May 12, 2010Dec 17, 2013Lifeline Scientific, Inc.Apparatus and method for maintaining and/or restoring viability of organs
US20100288723 *May 15, 2009Nov 18, 2010Clean Designs, LLCHydration bottle
US20120042663 *Feb 25, 2009Feb 23, 2012Ideapro GmbhCooling element with sub-cooling protection
EP0157751A2 *Apr 1, 1985Oct 9, 1985Lars-Erik LejondahlThermally insulated container
EP0159209A1 *Feb 21, 1985Oct 23, 1985Patrick HalesEmergency container for an accidentally amputated limb
EP0360944A1 *Sep 29, 1988Apr 4, 1990Celaster Societe Anonyme Dite:Device comprising a survival container for viable isolated organs
EP2098809A1 *Mar 6, 2008Sep 9, 2009Roche Diagnostics GmbHCooling element with excessive cooling protection
EP2179648A1 *Oct 14, 2009Apr 28, 2010Maco PharmaAssembly for the preparation of organs to be transplanted
WO1990000595A1 *Jun 19, 1989Jan 25, 1990Albert J BanesFloating cell culture device and method
WO1994003378A1 *Jul 28, 1993Feb 17, 1994Smith & Nephew Richards IncBiomedical material shipment kit and method
WO1995022727A1 *Feb 21, 1995Aug 24, 1995Hopital Cantonal UniversitaireTransportable refrigerating container
WO1996030111A1 *Mar 27, 1996Oct 3, 1996Life Resuscitation TechPortable device for preserving organs by static storage or perfusion
WO2003060399A1 *Jan 9, 2003Jul 24, 2003Photothera IncApparatus for preserving tissue
WO2009109494A1 *Feb 25, 2009Sep 11, 2009Ideapro GmbhCooling element with sub-cooling protection
Classifications
U.S. Classification435/1.1, 62/463, 220/771, 62/372, 435/284.1, 62/457.1, 62/64, 62/371
International ClassificationA61F7/10, F25D3/00
Cooperative ClassificationF25D2331/804, F25D2303/081, F25D3/00, A61F2007/101
European ClassificationF25D3/00