|Publication number||US3823717 A|
|Publication date||Jul 16, 1974|
|Filing date||Apr 16, 1973|
|Priority date||Apr 22, 1972|
|Also published as||DE2219790A1, DE2219790B2, DE2219790C3|
|Publication number||US 3823717 A, US 3823717A, US-A-3823717, US3823717 A, US3823717A|
|Inventors||Cichos M, Pohlman R|
|Original Assignee||Pohlman R|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (3), Referenced by (158), Classifications (13)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent [191 Pohlman et a1.
APPARATUS'FOR DISINTEGRATING CONCRETIONS IN BODY CAVITIES OF LIVING ORGANISMS BY MEANS OF AN ULTRASONIC PROBE Reimar Pohlman; Manfred Cichos, both of Aachen, Germany Assignee: Reimar Pohlman, Aachen, Germany Filed: Apr. 16, 1973 Appl. No.: 351,140
Foreign Application Priority Data Apr. 22, 1972 Germany 2219790 U.S. Cl 128/305, 128/276, 128/328, 128/24 A Int. Cl A6lb 17/32 Field of Search 128/303, 24 A, 305, 276, 128/328, 319
Primary Examiner-Lawrence W. Trapp I [5 7 1 ABSTRACT An ultrasonic probe for disintegrating concretions e.g. urinary calculus, in body cavities comprises a probe tube, ultrasonically vibrated in a longitudinal direction, having at one end a tubular impact element loosely coupled to it in the direction of vibration. The impact element is provided on its free end with a cutting edge, preferably formed by a plurality of teeth. The disintegrated concretions are continuously evacuated through the tubular impact element and the tubular probe.
12 Claims, 7 Drawing Figures PATENTED JUL 1 s 1924 APPARATUS FOR DISINTEGRATING CONCRETIONS IN BODY CAVITIES OF LIVING ORGANISMS BY MEANS OF AN ULTRASONIC PROBE BACKGROUND OF THE INVENTION This invention relates to an apparatus for disintegrating concretions in body cavities of living organisms by means of an ultrasonic probe.
It is known to treat hard and brittle materials by means of ultrasonic vibrations. in this case a tool profiled in any desired manner and excited to longitudinal vibrations is lowered into the material to be treated with interposition of a boron carbide suspension. By this means perforations, dies etc. can be made in hard and brittle materials.
The present invention pursues a totally different purpose, namely to produce brittle fractures in hard and brittle bodies in order to destroy the said bodies, e.g. urinary calculus. By this means it is desired to destroy or disintegrate a urinary calculus presentin the human bladder to such an extent that the debris can be exhausted or removed from the bladder through natural channels without difficulty.
Now when it is attempted to obtain brittle fractures by means of ultrasonic vibrations, although e.g. in the case of disintegration of urinary calculus, relatively soft types of calculus such as phosphate calculus, can be reduced fairly rapidly by ultrasonic vibrations; on the other hand harder types, such as urate Calculus, oxalate calculus, can only be disintegrated into small debris extraordinarily slowly, or even not at all.
Known apparatusses operate on the principle that a concretion present in a body cavity is touched by a rodshaped ultrasonic probe introduced through natural channels, whereupon by pressing the concretion against the wall of the body cavity the ultrasonic vibrations are transmitted to the concretion and the latter is thereby destroyed. Because the pressure forces required in this case are relatively powerful. there is a risk, more particularly with small smooth concretions, that the sonic probe may slip off, so that the wall of the body cavity may become damaged. Moreover, if such small smooth concretions are also extremely hard, then in the majority of cases they cannot be disintegrated at all by this procedure, because they move away at the very first contact by the ultrasonic probe.
Furthermore, the known apparatus suffers from an other disadvantage. When it is actually possible to disintegrate a concretion, then in every case initially the disintegrated debris of the calculus and the stone dust suspended in the liquor are left behind in the body cavity. This gives rise to on the one hand to a visual obstruction for the optical examination instrument (endoscope) introduced with the ultrasonic probe, and on the other hand to the necessity of removing the stone residues from the body cavity by a separate operation, which furthermore can no longer be performed under visual control. For this purpose the ultrasonic probe must be removed out of the body cavity and another instrument, for example a so-called suction syringe, must be used.
SUMMARY OF THE lNVENTlON The invention aims at providing an apparatus for disintegrating concretions in body cavities by means of an ultrasonic probe, whereby the disadvantages of the apparatusses of this type hitherto known are obviated.
To this end, the present invention consists in an apparatus for disintegrating concretions in body cavities in living organisms, comprising a tubular probe ultrasonically vibrated longitudinally and a tubular impact element loosely coupled in the direction of vibration to one end of said tubular probe whereby the ultrasonic vibrations transmitted to the impact element are transformed into shock forces.
Due to the interposition of the impact element, the shattering effect of the ultrasonic vibrations is increased by orders of magnitude. The impact element should be as hard and highly elastic as possible, and is arranged loosely between the ultrasonic probe and the body to be disintegrated. This unyielding element is capable of collecting impulse shocks statistically from the ultrasonic vibrations acting periodically upon it, and to transmit them in very brief and highly intensive impact shocks to the body to be disintegrated. lt has been found that these collected" highly intensive impulse shocks can achieve orders of magnitude and can initiate percussive forces which exceed many times the pressure peaks transmitted periodically by the ultrasonic probe tube and are capable of causing the desired brittle fractures. Even the hardest types or urinary calculus (urate and oxalate calculus) can be destroyed by this means.
By virtue of the tubular construction of the impact element and of the ultrasonic probe tube, it becomes possible to exhaust the fragments of calculus continuously by an exhauster device as they are detached during the actual disintegration operation, so that it is unnecessary to use additionally a further apparatus to exhaust them after the disintegration of the concretion. Furthermore, the continuous exhaustion of the fragments of calculus and of the stone dust produce the further advantage that no obstruction of vision for the optical observation instrument (endoscope) occurs. And
lastly, the exhaustion of the fragments of calculus also sucks the calculus itself towards the front end of the tubular impact element, so that on the one hand it centres itself automatically upon the impact element, so that the latter is largely prevented from slipping off, while at the same time a certain'contact pressure is generated whereby the contact force against the wall of the body cavity which was hitherto necessary is substantially reduced. Since furthermore the shocks of the impact element only have a destructive effect when they strike hard bodies, no injury to the soft wall of the body cavity occurs even if the latter is accidentally touched.
The characteristic property of the impact element to transform the ultrasonic vibrations transmitted to it into powerful shock forces of low frequency produces a number of advantages:
Only a much weaker contact pressure is required to achieve the desired effect, compared to the apparatusses hitherto known. Furthermore, it is possible to destroy with ultrasonic vibrations of hitherto customary amplitude and power, concretions which would have withstood destruction without the interposition of an impact element.
Preferably, the end of the tubular impact element remote from said coupling is constructed as a cutting edge which may advantageously be constituted by a plurality of teeth. The efficacity of the destruction of concretions is increased by these measures.
It is furthermore advantageous to make the teeth of undercut trapezoidal construction so that their cutting surfaces are larger than their root surfaces, since in this manner the disintegrated culculus material can easily be discharged by the exhaustion operation. Furthermore, if the teeth are arranged mutually joggled or twisted, so that their cutting edges project partly beyond the outer circumference of the tube supporting them and into the interior space of the said tube, then on the one hand the risk of the impact element seizing in the calculus is reduced, while on the other hand it has the effect that the diameter of the hole generated is greater than the diameter of the impact element carrying the teeth, and the stone fragments are smaller than the internal diameter of the impact element and of the tubular ultrasonic probe. In this way a clogging of the entire instrument by the disintegrated stones is reliably obviated. Furthermore the advantage is obtained that with this mode of construction the tubular impact element tends to dance" in the peripheral direction, so that it repeatedly strikes fresh points of the concretion to be destroyed.
The impact element is preferably guided loosely with slight radial and axial play on the end of the ultrasonic probe tube. In this case the impact element can be prevented from falling out by various measures which later be more fully explained.
It has further been found particularly advantageous to construct the ultrasonic vibrator tube and/or the impact element coupled to it, at the mutual contact surfaces, so that a linear or punctiform contact occurs, since in the case of an areal contact the recoil of the element is considerably impaired by the adherence layer of interlying liquid. The elastic shock conditions are also appreciably improved.
BRIEF DESCRIPTION OF THE DRAWINGS In order that the invention may be more readily understood. reference is made to the accompanying drawings which illustrate diagrammatically and by way of example several embodiments thereof, and in which:
FIG. 1 shows the front end of an ultrasonic probe with tubular impact element. partly in section;
FIG. 2 shows the side elevation of the cutting edge of the impact element with trapezoidal teeth;
FIG. 3 shows the plan of the cutting edge with twisted teeth and of the impact-element (in a section along the line III-III of FIG. 1);
FIG. 4 shows an impact element with rounded and corrugated impact surface;
FIG. 5 shows an impact element with conical impact surface and cap sleeve;
FIG. 6 shows an impact element with helicoidal spring retaining means; and
FIG. 7 shows an impact element with tubular retaining means.
DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring to FIG. 1, an ultrasonic probe comprises a tube 1 and an impact element 2. The tube 1 is oscillated longitudinally by an ultrasonic generator indicated by the double arrow 27. The impact element 2 is likewise of tubular construction and carries at one end teeth 7 as a cutting edge. Due to the longitudinal oscillations of the tube 1, impulses are transmitted to the impact element 2, which are intensified in the above described manner into very powerful impulse peaks, because the "impact element 2 is supported loosely in the radial and axial direction in or on the tube 1. The loose mounting ofthe impact element is ensured in that a sufficient tolerance in the radial direction is provided by shank guide means 4 in the end of the tube 1, whilst axial movement of the impact element 2 is limited on the one hand by an impact surface 3 on the element 2 and on the other hand by retaining pins 5, 5 which engage in slots 6, 6' in the impact element 2, so that the impact element 2 is prevented from dropping out of the tube 1. The teeth 7 of the impact element 2 constructed as a tube section are arranged joggled, so that only those fragments of the concretion treated which have a smaller diameter than that of the tube can penetrate into the tube 1, so that easy evacuation of the fragments in the direction of the arrow 27 through the tube 1 is possible.
As FIG. 2 shows, the teeth 7 are advantageously of trapezoidal construction with their wide side acting as chisels, so that they do not jam in the case ofa less brittle concretions, but can automatically bore themselves free. The discharge of the material to the exhaustor device is furthermore greatly facilitated by this means.
FIG. 3 illustrates the impact element 2 viewed axially in plan and partly in section along the line Ill-Ill of FIG. 1. The teeth 7 are arranged twisted so that a line connecting the outer edges of the teeth has a greater diameter than the outside diameter D of the impact element 2, whilst a line connecting the inner edges of the teeth has a smaller diameter than the inside diameter d of the impact element 2.
FIG. 4 shows a construction of the impact surfaces at the front end of the ultrasonic probe tube 8 and on the impact element 9. The end of the tube 8 is substantially conically countersunk at its end face 9a, whereby an automatic centering of the impact element 9 is created. The impact element 9 is rounded at its contact surface 10, so that its rests not upon a plane surface but only upon an encircling line. If desired, the rounded support surfaces 10 may be corrugated as at 100, so that only support points remain.
FIG. 5 shows the mode of supporting an impact element 1] on an ultrasonic probe tube 12 by a cap sleeve 13. In this case, for the purpose of automatic centering, both the impact surfaces l4, 15 are conically tapered.
FIG. 6 illustrates an embodiment in which an impact element 16 is loosely supported on an ultrasonic probe tube 17 by means of a helical spring 18. The spring is dimensioned so that in the rest position a small gap 19 remains between the impact element I6 and the tube 17, which is closed only when the impact element 16 is pressed against the tube 17, so that energy is transmitted only then. By virtue of this construction, during idle running, the excited but inoperative ultrasonic vibrator does not touch the impact element at all and avoids unnecessary wear of the impact surfaces and stressing of the support means.
FIG. 7 shows means for supporting an impact element 20 on an ultrasonic probe tube 21 by means of a soft resilient sleeve 22 which can be adjusted so that again a small gap 23 remains between impact surfaces 24, 25. The impact surfaces may be rounded and/or conically tapered.
1. An apparatus for disintegrating concretions in body cavities in living organisms, comprising a tubular probe adapted to be ultrasonically vibrated longitudinally and a tubular impact element loosely coupled in the direction of vibration to one end of said tubular probe whereby the ultrasonic vibrations transmitted to the impact element are transformed into shock forces.
2. An apparatus as claimed in claim I, wherein the end of the tubular impact element remote from said coupling is constructed as a cutting edge.
3. An apparatus as claimed in claim 2, wherein the cutting edge is constituted by a plurality of teeth.
4. An apparatus as claimed in claim 3, wherein the teeth are of an undercut. trapezoidal construction so that their cutting surfaces are larger than their root surfaces.
5. An apparatus as claimed in claim 3, wherein the teeth are arranged mutually joggled or twisted so that a line connecting the outer edges of the teeth has a greater diameter than the external diameter of the impact element and a line connecting the inner edges of the teeth has a smaller diameter than the internal diameter of the impact element.
6. An apparatus as claimed in any of the claim 2, wherein the impact element is guided loosely with slight radial and axial play on the end of the tubular probe.
7. An apparatus as claimed in claim 6, wherein the impact element is prevented from dropping out of the tubular probe by retaining pins which engage in slots provided in the impact element.
8. An apparatus as claimed in claim 6, wherein the impact element is loosely supported by a cap sleeve secured to the tubular probe.
9. An apparatus as claimed in claim 6, wherein the impact element is supported by a helicoidal spring contacting the tubular probe and the impact element.
10. An apparatus as claimed in claim 6, wherein the impact element is supported by a resilient tube contacting the tubular probe and the impact element.
11. An apparatus as claimed in claim 6, wherein those parts of the ultrasonic probe tube and of the impact element where the two components are in mutual contact during their axial movement caused by the ultrasonic vibrations are of tapered construction of at least one of said parts.
12. An apparatus as claimed in claim 1, wherein the ultrasonic probe tube is adapted to be connected to an exhaustor device.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3352303 *||Jul 28, 1965||Nov 14, 1967||Lawrence J Delaney||Method for blood clot lysis|
|US3433226 *||Jul 21, 1965||Mar 18, 1969||Aeroprojects Inc||Vibratory catheterization apparatus and method of using|
|US3526219 *||Jul 21, 1967||Sep 1, 1970||Ultrasonic Systems||Method and apparatus for ultrasonically removing tissue from a biological organism|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US4748971 *||Jan 30, 1987||Jun 7, 1988||German Borodulin||Vibrational apparatus for accelerating passage of stones from ureter|
|US4750488 *||Feb 27, 1987||Jun 14, 1988||Sonomed Technology, Inc.||Vibration apparatus preferably for endoscopic ultrasonic aspirator|
|US4750902 *||May 19, 1986||Jun 14, 1988||Sonomed Technology, Inc.||Endoscopic ultrasonic aspirators|
|US4823793 *||Oct 30, 1985||Apr 25, 1989||The United States Of America As Represented By The Administrator Of The National Aeronuautics & Space Administration||Cutting head for ultrasonic lithotripsy|
|US4838853 *||Feb 5, 1987||Jun 13, 1989||Interventional Technologies Inc.||Apparatus for trimming meniscus|
|US4907572 *||Apr 18, 1989||Mar 13, 1990||Urological Instruments Research, Inc.||Vibrational method for accelerating passage of stones from ureter|
|US4911149 *||Sep 7, 1988||Mar 27, 1990||Urological Instruments Research, Inc.||Vibratory treatment method and apparatus|
|US4922902 *||Dec 16, 1987||May 8, 1990||Valleylab, Inc.||Method for removing cellular material with endoscopic ultrasonic aspirator|
|US5019083 *||Jan 31, 1989||May 28, 1991||Advanced Osseous Technologies, Inc.||Implanting and removal of orthopedic prostheses|
|US5058570 *||Nov 27, 1986||Oct 22, 1991||Sumitomo Bakelite Company Limited||Ultrasonic surgical apparatus|
|US5103556 *||Sep 14, 1990||Apr 14, 1992||Circon Corporation||Method of manufacturing an electrohydraulic probe|
|US5116343 *||Aug 28, 1990||May 26, 1992||Richard Wolf Gmbh||Device for disintegrating concretions disposed in body cavities|
|US5154722 *||Sep 14, 1990||Oct 13, 1992||Circon Corporation||Electrohydraulic probe having a controlled discharge path|
|US5243997 *||Sep 14, 1992||Sep 14, 1993||Interventional Technologies, Inc.||Vibrating device for a guide wire|
|US5246447 *||Mar 5, 1992||Sep 21, 1993||Physical Sciences, Inc.||Impact lithotripsy|
|US5267954 *||May 5, 1992||Dec 7, 1993||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5269291 *||Dec 10, 1990||Dec 14, 1993||Coraje, Inc.||Miniature ultrasonic transducer for plaque ablation|
|US5284484 *||May 29, 1991||Feb 8, 1994||Advanced Osseous Technologies, Inc.||Apparatus for implantation and extraction of osteal prostheses|
|US5295955 *||Feb 14, 1992||Mar 22, 1994||Amt, Inc.||Method and apparatus for microwave aided liposuction|
|US5304115 *||Jan 11, 1991||Apr 19, 1994||Baxter International Inc.||Ultrasonic angioplasty device incorporating improved transmission member and ablation probe|
|US5312328 *||Jul 9, 1992||May 17, 1994||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5318570 *||Jun 11, 1991||Jun 7, 1994||Advanced Osseous Technologies, Inc.||Ultrasonic tool|
|US5324255 *||Jul 10, 1992||Jun 28, 1994||Baxter International Inc.||Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm|
|US5324297 *||Mar 5, 1991||Jun 28, 1994||Advanced Osseous Technologies, Inc.||Ultrasonic tool connector|
|US5326342 *||Jul 8, 1992||Jul 5, 1994||Baxter International Inc.||Ultrasonic angioplasty device incorporating all ultrasound transmission member made at least partially from a superlastic metal alloy|
|US5334183 *||Apr 9, 1992||Aug 2, 1994||Valleylab, Inc.||Endoscopic electrosurgical apparatus|
|US5342292 *||May 24, 1993||Aug 30, 1994||Baxter International Inc.||Ultrasonic ablation device adapted for guidewire passage|
|US5344395 *||Jan 24, 1992||Sep 6, 1994||Scimed Life Systems, Inc.||Apparatus for intravascular cavitation or delivery of low frequency mechanical energy|
|US5368557 *||May 5, 1993||Nov 29, 1994||Baxter International Inc.||Ultrasonic ablation catheter device having multiple ultrasound transmission members|
|US5368558 *||Jun 3, 1993||Nov 29, 1994||Baxter International Inc.||Ultrasonic ablation catheter device having endoscopic component and method of using same|
|US5380273 *||May 19, 1993||Jan 10, 1995||Dubrul; Will R.||Vibrating catheter|
|US5380274 *||Oct 12, 1993||Jan 10, 1995||Baxter International Inc.||Ultrasound transmission member having improved longitudinal transmission properties|
|US5382228 *||Sep 28, 1993||Jan 17, 1995||Baxter International Inc.||Method and device for connecting ultrasound transmission member (S) to an ultrasound generating device|
|US5382251 *||Feb 14, 1992||Jan 17, 1995||Biomet, Inc.||Plug pulling method|
|US5390678 *||Oct 12, 1993||Feb 21, 1995||Baxter International Inc.||Method and device for measuring ultrasonic activity in an ultrasound delivery system|
|US5397301 *||Jul 19, 1993||Mar 14, 1995||Baxter International Inc.||Ultrasonic angioplasty device incorporating an ultrasound transmission member made at least partially from a superelastic metal alloy|
|US5405318 *||Sep 28, 1993||Apr 11, 1995||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5417672 *||Oct 4, 1993||May 23, 1995||Baxter International Inc.||Connector for coupling an ultrasound transducer to an ultrasound catheter|
|US5425735 *||Sep 22, 1993||Jun 20, 1995||Psi Medical Products, Inc.||Shielded tip catheter for lithotripsy|
|US5427118 *||Oct 4, 1993||Jun 27, 1995||Baxter International Inc.||Ultrasonic guidewire|
|US5443078 *||Jun 29, 1994||Aug 22, 1995||Interventional Technologies, Inc.||Method for advancing a guide wire|
|US5447509 *||Oct 4, 1993||Sep 5, 1995||Baxter International Inc.||Ultrasound catheter system having modulated output with feedback control|
|US5456686 *||Oct 25, 1993||Oct 10, 1995||Biomet, Inc.||Implantation and removal of orthopedic prostheses|
|US5474530 *||Jun 8, 1994||Dec 12, 1995||Baxter International Inc.||Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasospasm|
|US5492528 *||Dec 5, 1994||Feb 20, 1996||Anis; Azis Y.||Removal of tissue|
|US5524635 *||Oct 24, 1994||Jun 11, 1996||Interventional Technologies Inc.||Apparatus for advancing a guide wire|
|US5562609 *||Oct 7, 1994||Oct 8, 1996||Fibrasonics, Inc.||Ultrasonic surgical probe|
|US5562610 *||Oct 7, 1994||Oct 8, 1996||Fibrasonics Inc.||Needle for ultrasonic surgical probe|
|US5626560 *||Nov 13, 1995||May 6, 1997||Soring Medizintechnik Gmbh||Diathermic hand-held instrument with an endoscopic probe|
|US5722945 *||Apr 1, 1996||Mar 3, 1998||Aziz Yehia Anis||Removal of tissue|
|US5725570 *||Feb 29, 1996||Mar 10, 1998||Boston Scientific Corporation||Tubular medical endoprostheses|
|US5730718 *||Apr 29, 1996||Mar 24, 1998||Aziz Yehia Anis||Removal of tissue|
|US5827292 *||Feb 12, 1996||Oct 27, 1998||Anis; Aziz Yehia||Removal of tissue|
|US5906623 *||Jul 29, 1997||May 25, 1999||Boston Scientific Corporation||Lithotripsy system|
|US5957882 *||Mar 12, 1997||Sep 28, 1999||Advanced Cardiovascular Systems, Inc.||Ultrasound devices for ablating and removing obstructive matter from anatomical passageways and blood vessels|
|US6277084||May 5, 1997||Aug 21, 2001||Boston Scientific Corporation||Ultrasonic medical device|
|US6287271||Jan 9, 1998||Sep 11, 2001||Bacchus Vascular, Inc.||Motion catheter|
|US6287331||May 12, 1998||Sep 11, 2001||Boston Scientific Corporation||Tubular medical prosthesis|
|US6290721||Oct 21, 1997||Sep 18, 2001||Boston Scientific Corporation||Tubular medical endoprostheses|
|US6375651||Feb 18, 2000||Apr 23, 2002||Scimed Life Systems, Inc.||Laser lithotripsy device with suction|
|US6440123 *||Apr 9, 1998||Aug 27, 2002||Konrad Engel||Metal probe for use in intracorporeal lithotripsy|
|US6497709||May 5, 1997||Dec 24, 2002||Boston Scientific Corporation||Metal medical device|
|US6508782||Aug 16, 2000||Jan 21, 2003||Bacchus Vascular, Inc.||Thrombolysis device|
|US6517531||Apr 27, 2001||Feb 11, 2003||Scimed Life Systems, Inc.||Medical suction device|
|US6527802||Sep 23, 1997||Mar 4, 2003||Scimed Life Systems, Inc.||Clad composite stent|
|US6689086||Jul 29, 1999||Feb 10, 2004||Advanced Cardiovascular Systems, Inc.||Method of using a catheter for delivery of ultrasonic energy and medicament|
|US6726681||Mar 15, 2002||Apr 27, 2004||Scimed Life Systems, Inc.||Laser lithotripsy device with suction|
|US6752801 *||Jun 27, 2002||Jun 22, 2004||Konrad Engel||Metal probe for intracorporeal calculi crushing|
|US6929632||Jun 27, 2002||Aug 16, 2005||Advanced Cardiovascular Systems, Inc.||Ultrasonic devices and methods for ablating and removing obstructive matter from anatomical passageways and blood vessels|
|US6936025||Nov 1, 2000||Aug 30, 2005||Bacchus Vascular, Inc.||Thrombolysis device|
|US6942677||Feb 26, 2003||Sep 13, 2005||Flowcardia, Inc.||Ultrasound catheter apparatus|
|US7101392||Aug 8, 2001||Sep 5, 2006||Boston Scientific Corporation||Tubular medical endoprostheses|
|US7104983||Mar 16, 2004||Sep 12, 2006||Boston Scientific Scimed, Inc.||Laser lithotripsy device with suction|
|US7137963||Aug 26, 2002||Nov 21, 2006||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US7220233||Apr 8, 2003||May 22, 2007||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US7335180||Nov 24, 2003||Feb 26, 2008||Flowcardia, Inc.||Steerable ultrasound catheter|
|US7393330||Feb 16, 2006||Jul 1, 2008||Broncus Technologies, Inc.||Electrosurgical device having hollow tissue cutting member and transducer assembly|
|US7422563||Feb 21, 2002||Sep 9, 2008||Broncus Technologies, Inc.||Multifunctional tip catheter for applying energy to tissue and detecting the presence of blood flow|
|US7462162||Jul 19, 2004||Dec 9, 2008||Broncus Technologies, Inc.||Antiproliferative devices for maintaining patency of surgically created channels in a body organ|
|US7540852||Aug 26, 2004||Jun 2, 2009||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US7540868||Nov 4, 2002||Jun 2, 2009||Boston Scientific Scimed, Inc.||Medical suction device|
|US7540870||Aug 27, 2007||Jun 2, 2009||Bacoustics, Llc||Ablative ultrasonic-cryogenic apparatus|
|US7604608||Jan 14, 2003||Oct 20, 2009||Flowcardia, Inc.||Ultrasound catheter and methods for making and using same|
|US7621902||Aug 24, 2006||Nov 24, 2009||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US7621929||Jul 11, 2005||Nov 24, 2009||Flowcardia, Inc.||Ultrasound catheter apparatus|
|US7708712||Jul 19, 2004||May 4, 2010||Broncus Technologies, Inc.||Methods and devices for maintaining patency of surgically created channels in a body organ|
|US7803168||Dec 9, 2005||Sep 28, 2010||The Foundry, Llc||Aortic valve repair|
|US7955293||Aug 23, 2006||Jun 7, 2011||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US8043251||Aug 7, 2009||Oct 25, 2011||Flowcardia, Inc.||Ultrasound catheter and methods for making and using same|
|US8062289||Apr 24, 2009||Nov 22, 2011||Bacoustics, Llc||Ablative ultrasonic-cryogenic apparatus|
|US8062566||Jul 25, 2006||Nov 22, 2011||Flowcardia, Inc.||Method of manufacturing an ultrasound transmission member for use in an ultrasound catheter device|
|US8100892||Apr 24, 2009||Jan 24, 2012||Boston Scientific Scimed, Inc.||Medical suction device|
|US8133236||Nov 7, 2006||Mar 13, 2012||Flowcardia, Inc.||Ultrasound catheter having protective feature against breakage|
|US8152753||Aug 7, 2009||Apr 10, 2012||Flowcardia, Inc.||Ultrasound catheter and methods for making and using same|
|US8221343||Jan 20, 2005||Jul 17, 2012||Flowcardia, Inc.||Vibrational catheter devices and methods for making same|
|US8226566||Jun 12, 2009||Jul 24, 2012||Flowcardia, Inc.||Device and method for vascular re-entry|
|US8246643||Jul 18, 2008||Aug 21, 2012||Flowcardia, Inc.||Ultrasound catheter having improved distal end|
|US8308677||Jun 3, 2011||Nov 13, 2012||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US8409167||Oct 5, 2006||Apr 2, 2013||Broncus Medical Inc||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8496669||Dec 21, 2007||Jul 30, 2013||Flowcardia, Inc.||Ultrasound catheter having protective feature against breakage|
|US8506519||Jul 16, 2007||Aug 13, 2013||Flowcardia, Inc.||Pre-shaped therapeutic catheter|
|US8608724||Nov 4, 2010||Dec 17, 2013||Broncus Medical Inc.||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8613751||Jan 28, 2008||Dec 24, 2013||Flowcardia, Inc.||Steerable ultrasound catheter|
|US8617096||Feb 1, 2011||Dec 31, 2013||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US8641630||Jul 7, 2010||Feb 4, 2014||Flowcardia, Inc.||Connector for securing ultrasound catheter to transducer|
|US8647293||May 22, 2008||Feb 11, 2014||Flowcardia, Inc.||Therapeutic ultrasound system|
|US8668709||Feb 25, 2008||Mar 11, 2014||Flowcardia, Inc.||Steerable ultrasound catheter|
|US8672928||Dec 16, 2011||Mar 18, 2014||Boston Scientific Scimed, Inc.||Medical suction device|
|US8679049||Jul 17, 2012||Mar 25, 2014||Flowcardia, Inc.||Device and method for vascular re-entry|
|US8690819||Nov 9, 2012||Apr 8, 2014||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US8709034||May 13, 2011||Apr 29, 2014||Broncus Medical Inc.||Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall|
|US8784400||May 16, 2012||Jul 22, 2014||Broncus Medical Inc.||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8790291||Apr 22, 2009||Jul 29, 2014||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US8932316||Apr 7, 2014||Jan 13, 2015||Broncus Medical Inc.||Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall|
|US8956375||Sep 23, 2011||Feb 17, 2015||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US8961423||Oct 1, 2009||Feb 24, 2015||Flowcardia, Inc.||Ultrasound catheter apparatus|
|US9034032||Jul 19, 2013||May 19, 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9034033||Jul 19, 2013||May 19, 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9039757||Mar 15, 2013||May 26, 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9113935 *||May 9, 2014||Aug 25, 2015||Gyrus Acmi, Inc.||Oscillating lithotripter|
|US9125740||Jul 23, 2013||Sep 8, 2015||Twelve, Inc.||Prosthetic heart valve devices and associated systems and methods|
|US9168099||Mar 13, 2013||Oct 27, 2015||Gyrus Acmi, Inc.||Lithotripsy apparatus using a flexible endoscope|
|US9186164||Mar 13, 2013||Nov 17, 2015||Gyrus Acmi, Inc.||Impact lithotripsy tip|
|US20020128647 *||Feb 21, 2002||Sep 12, 2002||Ed Roschak||Devices for applying energy to tissue|
|US20030009125 *||Jun 27, 2002||Jan 9, 2003||Henry Nita||Ultrasonic devices and methods for ablating and removing obstructive matter from anatomical passageways and blood vessels|
|US20030078566 *||Nov 4, 2002||Apr 24, 2003||Scimed Life Systems, Inc.||Medical suction device|
|US20040039311 *||Aug 26, 2002||Feb 26, 2004||Flowcardia, Inc.||Ultrasound catheter for disrupting blood vessel obstructions|
|US20040138570 *||Jan 14, 2003||Jul 15, 2004||Flowcardia, Inc., A Delaware Corporation||Ultrasound catheter and methods for making and using same|
|US20040167507 *||Feb 26, 2003||Aug 26, 2004||Flowcardia, Inc.||Ultrasound catheter apparatus|
|US20040204670 *||Apr 8, 2003||Oct 14, 2004||Flowcardia, Inc., A Delaware Corporation||Ultrasound catheter devices and methods|
|US20040243123 *||Mar 16, 2004||Dec 2, 2004||Scimed Life Systems, Inc.||Laser lithotripsy device with suction|
|US20050043752 *||Jul 19, 2004||Feb 24, 2005||Broncus Technologies, Inc.||Methods and devices for maintaining patency of surgically created channels in a body organ|
|US20050113688 *||Nov 24, 2003||May 26, 2005||Flowcardia, Inc.,||Steerable ultrasound catheter|
|US20050245951 *||Jul 11, 2005||Nov 3, 2005||Flowcardia, Inc., A Delaware Corporation||Ultrasound catheter apparatus|
|US20060047239 *||Aug 26, 2004||Mar 2, 2006||Flowcardia, Inc.||Ultrasound catheter devices and methods|
|US20060161098 *||Jan 20, 2005||Jul 20, 2006||Flowcardia, Inc.||Vibrational catheter devices and methods for making same|
|US20060229659 *||Dec 9, 2005||Oct 12, 2006||The Foundry, Inc.||Aortic valve repair|
|US20080039745 *||Aug 27, 2007||Feb 14, 2008||Bacoustics Llc||Ablative ultrasonic-cryogenic apparatus|
|US20080097251 *||Jun 15, 2006||Apr 24, 2008||Eilaz Babaev||Method and apparatus for treating vascular obstructions|
|US20080172067 *||Feb 25, 2008||Jul 17, 2008||Flowcardia, Inc.||Steerable ultrasound catheter|
|US20090099536 *||Nov 6, 2007||Apr 16, 2009||Takayuki Akahoshi Akahoshi||Bidirectional Phacoemulsification Needle Tips for Torsional and Longitudinal Motion|
|US20100049209 *||Oct 1, 2009||Feb 25, 2010||Flowcardia, Inc.||Ultrasound catheter apparatus|
|US20140336666 *||May 9, 2014||Nov 13, 2014||Gyrus Acmi, Inc., D.B.A. Olympus Surgical Technologies America||Oscillating lithotripter|
|USRE37024||Sep 12, 1997||Jan 16, 2001||Boston Scientific Corporation||Endoscopic lithotripsy system|
|CN101401755B||Sep 25, 2008||Jan 23, 2013||株式会社尼德克||Head for ultrasonic operation and knife head for ultrasonic operation|
|EP0617590A1 *||Dec 16, 1992||Oct 5, 1994||Psi Medical Products, Inc.||Shielded tip catheter|
|EP0820727A2||May 4, 1993||Jan 28, 1998||Baxter International Inc.||Ultrasonic angioplasty catheter device|
|EP0820728A2||May 4, 1993||Jan 28, 1998||Baxter International Inc.||Ultrasonic angioplasty catheter device|
|EP2417945A2||Mar 19, 2004||Feb 15, 2012||Flowcardia Inc.||Improved ultrasound catheter devices and methods|
|EP2471474A1||Feb 13, 2004||Jul 4, 2012||Flowcardia Inc.||Ultrasound catheter apparatus|
|EP2609878A1||Mar 19, 2004||Jul 3, 2013||FlowCardia, Inc.||Improved ultrasound catheter devices and methods|
|WO1990009762A1 *||Feb 22, 1990||Sep 7, 1990||Physical Sciences Inc||Acoustic impact delivery catheter with end cap|
|WO1993011711A1 *||Dec 16, 1992||Jun 24, 1993||Psi Medical Products Inc||Shielded tip catheter|
|WO1996039955A1 *||Oct 11, 1995||Dec 19, 1996||Will R Dubrul||Vibrating catheter|
|WO2004018019A2||Aug 26, 2003||Mar 4, 2004||Flowcardia Inc||Ultrasound catheter for disrupting blood vessel obstructions|
|WO2004093736A2||Mar 19, 2004||Nov 4, 2004||Flowcardia Inc||Improved ultrasound catheter devices and methods|
|WO2005053769A2||Oct 25, 2004||Jun 16, 2005||Flowcardia Inc||Steerable ultrasound catheter|
|WO2014183051A1 *||May 9, 2014||Nov 13, 2014||Gyrus Acmi, Inc., D.B.A. Olympus Surgical Technologies America||Oscillating lithotripter tip|
|U.S. Classification||606/128, 601/4, 604/22, 606/169|
|International Classification||A61B17/22, B02C19/18, B02C19/00, A61B17/32|
|Cooperative Classification||A61B17/22012, A61B2017/320072, B02C19/18|
|European Classification||B02C19/18, A61B17/22B2|