|Publication number||US3825015 A|
|Publication date||Jul 23, 1974|
|Filing date||Dec 14, 1972|
|Priority date||Dec 14, 1972|
|Publication number||US 3825015 A, US 3825015A, US-A-3825015, US3825015 A, US3825015A|
|Original Assignee||American Optical Corp|
|Referenced by (107), Classifications (6), Legal Events (2) |
|External Links: USPTO, USPTO Assignment, Espacenet|
Single catheter for atrial and ventricular stimulation
US 3825015 A
United States Patent 91 Berkovits i 1 3,825,015 [451 July 23, 1974 1 SINGLE CATHETER FOR ATRIAL AND VENTRICULAR STIMULATION  Inventor: Barough V. Berkovits, Newton Highlands, Mass.
 Assignee: American Optical Corporation,
 Filed: Dec. 14, 1972  Appl. No.: 315,252
 US. Cl, 128/404, 128/419 P  Int. Cl A6ln 1/34  Field of Search.... 128/404, 418, 419 D, 419 P, 128/419 R  References Cited UNITED STATES PATENTS 3,253,595 5/1966 Murphy, Jr. et a1 128/419 P 3,478,746 11/1969 Greatbatch 128/419 P 3,595,242 Berkovits 128/419 P 7 l [L IL IL 3,718,142 2/1973 M ulier 128/419? Primary Examiner-William E. Kamm Attorney, Agent, or Firm-Joel Wall; William C.
Nealon 57 ABSTRACT A single catheter for atrial and ventricular stimulation. A single catheter is disclosed that provides separate electrical stimulation to the atrium and separate electrical stimulation to the ventricle on mutually insu- 3 Claims, 2 Drawing Figures t 1 SINGLE CATHETER FOR ATRIAL AND VENTRICULAR STIMULATION BACKGROUND OF THE INVENTION Description of Prior Art In the electro-medical field, therapeutic heat stimulating devices are well known. Some of these devices are heart pacers which providestimulation to the heart in order to cause the heart to beat. Some pacers provide stimulation only to a ventricle but another type of pacer provides sequential stimulation to both artrium and to ventricle to cause the heart to beat in a more efficient manner. This latter type of pacer is disclosed in US. Pat. No. 3,595,242 entitled Atrial and Ventricular Demand Pacer which has issued in the name of the inventor of the instant invention. Background material disclosed in this patent is incorporated herein by reference.
A problem associated with this type of improved heart pacing is that electrical contact made between the artium wall and the electrode may be difficult to maintain. This is due to the nature of the atrial chambers shape and motion. A solution to this problem is presented in a co-pending application Ser. No. 101,836 filed on Dec. 28, 1970 and which has since matured into U.S.,Pat. No. 3,729,008 and entitled Electrode for Atrial Pacingwith Curved End for Atrial Wall Engagement, wherein a hook-type electrode for gripping the atrium wall is disclosed. This type of electrode solves the atrial wall-electrode contact problem. However, use of this hook catheter for atrial stimulation necessitates a separate catheter for stimulation of the ventricle. Thus, two catheters are used which require additional surgical procedures. The instant invention solves both the electrical contact problem and the dual catheter problem. The present invention provides a single catheter which contains electrodes that separately stimulate both the atrium and the ventricle and simultaneously provide good contact the the atrium through electrode selection.
SUMMARY OF THEINVENTION A single catheter contains a plurality of mutually insulated electrical conductors which are electrically connected within the catheter to conductive rings. The rings extend through the surface of the catheter and are exposed to the heart chamber walls. They are spaced from each other to provide proper stimulation to atrium and ventricle. The catheter is designed to be in-- serted into the ventricle by way of the atrium and a atrium, but there may be as many rings as is conceivably practical. The distance between the two ventricular rings is selected for optimum performance as are the distances among the atrial rings.
Some of the atrial rings will make better contact with the atrium than others. These contacts are determined by testing different pairs of conductors after insertion of the catheter into the heart but prior to permanent connection to the heart stimulator. Thus, two of the atrial rings or terminals are selected for providing the stimulation, but more than two may be selected if it is felt that parallel paths of conductors in a particular case will provide a more reliable and efficient electrical contact. I
The construction of the catheter utilizes an electrostatic shield around the'ventricular electrodes therby electromagnetically separating atrial stimulation from ventricular stimulation. In a particular embodiment, the shield may be utilized as one of the conductors for ventricular stimulation.
It is an advantage of this invention to provide atrial and ventricular stimulation of the kind that may be utilized by a demand atrial and ventricular heart pacer where there is no need for separate atrial and ventricular catheters thereby reducing surgical problems involved.
It is thus an object of this invention to provide improved heart stimulation equipment.
It is yet another object of this invention to provide improved atrial and ventricular demand heart pacing.
part of the illustrative embodiment depicted in FIG. 1. I
. DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring to FIG. 1, enclosure 10 is intended to schematically represent the ventricle of a heart and enclo sure 12 is intended to schematically represent the atrium of the heart. Single catheter 30 is depicted as being inserted into ventricle 10 via atrium l2. Conductive rings 14 and 15 make electrical contact with the inside of the ventricle chamber, and conductive rings 16, 17, 18 and 19 are-conductively connected to the inside wall of the atrium chamber. Typical distances between rings 16, 17, 18 and 19 may be on the order of 1 centimeter respectively as may be the distance between rings 14 and 15. The distance between rings 15 and 16 is on the order of 6 centimeters. However, all these ring locations can be varied with respect to each other; the distances therebetween are not necessarily critical. However, the constraint of rings 14 and 15 lying in the ventricle and rings 16-19 lying in the atrium must be satisfied.
Terminal 24 is conductively connected to ring 14, terminal 25 is'conductively connected to ring 15, terminal 26 is conductively connected to ring 16, terminal 27 is conductively connected to ring 17, terminal 28 is conductively connected to ring 18, and terminal 29 is conductively connected to ring 19. The respective numbers with the .subscript I is intended to represent the respective insulated conductors. For example, insulated conductor 24l is associated with terminal 24.
Catheter portion 30 is illustrated as being broken away from catheter portion 31. However, these portions are part of the same catheter and are illustrated as such for the purpose of indicating relative distance. For example, the distance between catheter portion 30 and catheter portion 31 may be on the order of several feet.
Referring to FIG. 2, one observes the insulated conductors depicted in FIG. 1. Insulated conductor N is intended to mean that the number of insulated conductors contained within a catheter are to be limited only by physical space available and there is no special total number of catheters that can be used. Electro-static shield 40 is depicted as encompassing insulated conductors 241 and 251 which provide ventricular stimulation. Electro-static shield 40 effectively prevents interference from the stimulation provided on the ventricular conductors from being picked up by the atrial conductors and vice versa. In an alternative embodiment, one of the ventricular conductors can be comprised of shield 40 itself. Typically, but not necessarily, shield 40 is braided.
In a particular embodiment, the conductive rings 14-19 may be made from a platinum compound and the respective conductors contained within catheter 30 are welded to the inner portion of the conductive rings. The catheter itself may be constructed of a typical high grade durameter rubber which is normally used in surgical implantations. The conductors themselves in a particular embodiment may be ordinary conductive copper wire, but can also be constructed from coiled wire as well.
ln operation, catheter 30 is inserted through a blood vessel and into atrium 12. It is then further urged into ventricle so that catheter 30 comes torest in the manner schematically depicted. Conductive rings 14 and 15 make electrical contact with ventricle 10, and
conductive rings 16-19 make electrical contact with atrium 12. Although the catheter is depicted as linear, in reality it is a flexible tube and certain of the conductive rings will become located within the atrium 12 to provide better electrical contact than other of those rings. The best contacts are determinable from external measurements made on terminals 26-29 and at least two of the atrial rings are selected. More than two can be selected by utilizing two rings in parallel if this seems to be advisable. Otherwise,.the unselected electrodes need not be used.
The optimum electrode combination for best atrialventricular stimulation is thus selectable after insertion of the catheter into the heart. Since the size of the heart tends to vary from person to person, it is desirable to select from the above-described electrode stimulation to provide best electrical contact. The availability of these different contact combinations permits the adapt- 4 ing of this electrode to the size of the particular heart in which it is implanted and provides optimum contact. It is thus seen that the need for separate catheters, one for insertion into the ventricle, and another for insertion into the atrium,are eliminated by use of this single catheter for atrial and ventricular stimulation.
The invention may be embodied in other specific forms without departing from the spirit .or the essential characteristics thereof. It should be understood that the number of conductive rings utilized'is limited only by physical size. It should be understood further that the distancesbetween the atrial rings, the ventricular rings, and between the two groups, can be selected for optimum performance. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description. ltshould be further understood that no limitations are placed upon utilization of the invention with an implantable or external heart stimulating device. When utilized-with an implantable'devic'e, after the conductive measurements are made, the selected conductors are utilized, the others are ignored by sealing them within the catheter. Of course, in the external configuration the unused conductors are merely ignored without any sealing necessary. Thus, all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
What is claimed is:
1. A single catheter for use'with a heart stimulatorwhich generates electrical inpulses forthe purpose of separately stimulating the atrium-and ventricle of said heart, said catheter comprising first means for conductirg itrial stimulation from said stimulator to said atrium, said first means including a plurality of at least three insulated electrical conductors disposed internal to said single catheter and terminating at different locations along said catheter from which at least two said conductors are chosen to conduct said atrial stimulation, second means for conducting ventricular stimulation from said stimulator to said ventricle, and means for preventing electro-magnetic interference between said first and second stimulation application means.
2. A single catheter as recited in claim 1 and wherein said first means further includes a plurality of at least three regularly spaced conductive rings exposed to the surface of said catheter, each of said rings being conductively connected respectively to one of said plurality of at least three insulated electrical conductors.
3. A single catheter as recited in claim 2 and wherein said second means includes a plurality of at least two insulated electrical conductors disposed internal to said catheter and a plurality of at least two conductive rings exposed to the surface of said catheter where each of said plurality of at least two'conductive rings is conductively connected respectively to one of said plurality of at least two insulated electrical conductors.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3949757 *||May 13, 1974||Apr 13, 1976||Sabel George H||Catheter for atrio-ventricular pacemaker|
|US4010755 *||May 27, 1975||Mar 8, 1977||Preston Thomas A||Unipolar pacing catheter with plural distal electrodes|
|US4245645 *||Jul 20, 1978||Jan 20, 1981||Arseneault Pierre Michel||Self-locking cerebral electrical probe|
|US4365639 *||Mar 11, 1981||Dec 28, 1982||Applied Cardiac Electrophysiology||Catheter, cardiac pacemaker and method of pacing|
|US4379462 *||Oct 29, 1980||Apr 12, 1983||Neuromed, Inc.||Multi-electrode catheter assembly for spinal cord stimulation|
|US4444195 *||Nov 2, 1981||Apr 24, 1984||Cordis Corporation||Cardiac lead having multiple ring electrodes|
|US4458695 *||Jul 16, 1982||Jul 10, 1984||Cordis Corporation||Multipolar electrode assembly for pacing lead|
|US4481953 *||Dec 29, 1983||Nov 13, 1984||Cordis Corporation||Endocardial lead having helically wound ribbon electrode|
|US4522212 *||Nov 14, 1983||Jun 11, 1985||Mansfield Scientific, Inc.||Endocardial electrode|
|US4549548 *||Sep 14, 1983||Oct 29, 1985||Vitafin N.V.||Pacemaker system with automatic event-programmed switching between unipolar and bipolar operation|
|US4585004 *||Jun 1, 1984||Apr 29, 1986||Cardiac Control Systems, Inc.||Heart pacing and intracardiac electrogram monitoring system and associated method|
|US4592372 *||May 22, 1984||Jun 3, 1986||Cordis Corporation||Pacing/sensing electrode sleeve and method of forming same|
|US4614192 *||Mar 23, 1983||Sep 30, 1986||Mieczyslaw Mirowski||Implantable cardiac defibrillator employing bipolar sensing and telemetry means|
|US4699147 *||Sep 25, 1985||Oct 13, 1987||Cordis Corporation||Intraventricular multielectrode cardial mapping probe and method for using same|
|US4754753 *||Nov 12, 1985||Jul 5, 1988||Medtronic, Inc.||System for sensing electrical depolarization wave signals and their direction|
|US4832051 *||Jun 27, 1986||May 23, 1989||Symbion, Inc.||Multiple-electrode intracochlear device|
|US4848352 *||Jul 7, 1988||Jul 18, 1989||Telectronics, N.V.||Method for cardiac pacing and sensing using combination of electrodes|
|US4892102 *||Sep 26, 1986||Jan 9, 1990||Astrinsky Eliezer A||Cardiac pacing and/or sensing lead and method of use|
|US4917115 *||Jul 11, 1988||Apr 17, 1990||Vitatron Medical B. V.||Pacing system and method for physiological stimulation of the heart utilizing Doppler means|
|US4940064 *||Jun 30, 1987||Jul 10, 1990||Desai Jawahar M||Catheter for mapping and ablation and method therefor|
|US5127403 *||Aug 21, 1990||Jul 7, 1992||Cardiac Control Systems, Inc.||Pacemaker catheter utilizing bipolar electrodes spaced in accordance to the length of a heart depolarization signal|
|US5231995 *||Sep 30, 1992||Aug 3, 1993||Desai Jawahar M||Method for catheter mapping and ablation|
|US5365926 *||Oct 13, 1992||Nov 22, 1994||Desai Jawahar M||Catheter for mapping and ablation and method therefor|
|US5397339 *||May 7, 1993||Mar 14, 1995||Desai; Jawahar M.||Catheter for mapping and ablation and method therefor|
|US5398687 *||May 18, 1992||Mar 21, 1995||Wilson-Cook Medical Inc.||Methods for measuring motility within the biliary tract and instrumentation useful therefor|
|US5456706 *||Jan 4, 1994||Oct 10, 1995||Ventritex, Inc.||Cardiac defibrillation lead having defibrillation and atrial sensing electrodes|
|US5476497 *||Aug 15, 1994||Dec 19, 1995||Ann Mirowski||Oval electrode lead body|
|US5500011 *||Nov 4, 1994||Mar 19, 1996||Desai; Jawahar M.||Catheter for mapping and ablation and method therefor|
|US5529574 *||Aug 16, 1994||Jun 25, 1996||Frackelton; James P.||Method and apparatus for treatment of the prostate|
|US5545204 *||Mar 7, 1994||Aug 13, 1996||Cammilli; Leonardo||Sequential cardiostimulation system (DDD) using a single electrocatheter inserted through the coronary sinus|
|US5628778 *||Nov 21, 1994||May 13, 1997||Medtronic Inc.||Single pass medical electrical lead|
|US5701907 *||Dec 16, 1996||Dec 30, 1997||Hewlett-Packard Company||Electrocardiographic waveform monitoring method and system|
|US5800465 *||Oct 30, 1996||Sep 1, 1998||Medtronic, Inc.||System and method for multisite steering of cardiac stimuli|
|US5846196 *||Dec 12, 1996||Dec 8, 1998||Cordis Europa N.V.||Intravascular multielectrode cardiac mapping probe|
|US5922014 *||Sep 2, 1997||Jul 13, 1999||Medtronic, Inc.||Single pass lead and method of use|
|US5948014 *||Jan 23, 1998||Sep 7, 1999||Pacesetter, Inc.||Implantable stimulation system having a single-pass, tripolar lead and programmable polarity|
|US5978704 *||Jun 3, 1997||Nov 2, 1999||Uab Research Foundation||Method and apparatus for treating cardiac arrhythmia|
|US5987354 *||Oct 14, 1997||Nov 16, 1999||Uab Research Foundation||Dual shock atrial defibrillation apparatus|
|US5995876 *||Feb 3, 1997||Nov 30, 1999||Medtronic, Inc.||Single pass medical electrical lead|
|US6006131 *||Aug 13, 1996||Dec 21, 1999||Uab Research Foundation||Dual current pathway atrial defibrillation apparatus|
|US6006139 *||Feb 3, 1997||Dec 21, 1999||Medtronic, Inc.||Single pass medical electrical lead with cap electrodes|
|US6021354 *||Dec 31, 1998||Feb 1, 2000||Medtronic, Inc.||Single pass lead and method of use|
|US6122553 *||Sep 9, 1999||Sep 19, 2000||Uab Research Foundation||Method and apparatus for treating cardiac arrhythmia|
|US6201994||Nov 30, 1999||Mar 13, 2001||Medtronic, Inc.||Single pass lead and method of use|
|US6253109||Nov 5, 1998||Jun 26, 2001||Medtronic Inc.||System for optimized brain stimulation|
|US6327500||Nov 15, 1999||Dec 4, 2001||Uab Research Foundation||Dual shock atrial defibrillation apparatus|
|US6345198||Jul 29, 1999||Feb 5, 2002||Pacesetter, Inc.||Implantable stimulation system for providing dual bipolar sensing using an electrode positioned in proximity to the tricuspid valve and programmable polarity|
|US6470211||Aug 18, 2000||Oct 22, 2002||Uab Research Foundation||Method and apparatus for treating cardiac arrhythmia|
|US6480747||Jan 16, 2001||Nov 12, 2002||Quetzal Biomedical, Inc.||Cardiac electrode catheter and method of manufacturing same|
|US6484057||Dec 21, 2000||Nov 19, 2002||Uab Research Foundation||Pacing methods and devices for treating cardiac arrhythmias and fibrillation|
|US6484059||Mar 7, 2001||Nov 19, 2002||Medtronic, Inc.||Method for optimized brain stimulation for treating movement disorders|
|US6549812||Nov 29, 1999||Apr 15, 2003||Medtronic, Inc.||Medical electrical lead having bending stiffness which increase in the distal direction|
|US6556873||Nov 29, 1999||Apr 29, 2003||Medtronic, Inc.||Medical electrical lead having variable bending stiffness|
|US6711440||Apr 11, 2002||Mar 23, 2004||Biophan Technologies, Inc.||MRI-compatible medical device with passive generation of optical sensing signals|
|US6718203||Feb 19, 2002||Apr 6, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6718207||Feb 19, 2002||Apr 6, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6718211||Sep 6, 2001||Apr 6, 2004||Medtronic, Inc.||Medical electrical lead having bending stiffnesses which increase in the distal direction|
|US6725092||Apr 25, 2002||Apr 20, 2004||Biophan Technologies, Inc.||Electromagnetic radiation immune medical assist device adapter|
|US6731979||Aug 30, 2001||May 4, 2004||Biophan Technologies Inc.||Pulse width cardiac pacing apparatus|
|US6738673||Aug 21, 2002||May 18, 2004||Jawahar M. Desai||Method for catheter mapping and ablation|
|US6741893||Sep 6, 2001||May 25, 2004||Medtronic, Inc.||Medical electrical lead having variable bending stiffness|
|US6757566||Feb 19, 2002||Jun 29, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6760628||Feb 19, 2002||Jul 6, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6763268||Feb 19, 2002||Jul 13, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6778856||Feb 19, 2002||Aug 17, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6795736||Feb 19, 2002||Sep 21, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6799069||Feb 19, 2002||Sep 28, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6819954||Feb 19, 2002||Nov 16, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6819958||Feb 19, 2002||Nov 16, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6829509||Feb 19, 2002||Dec 7, 2004||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6845266||Feb 19, 2002||Jan 18, 2005||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6850805||Feb 19, 2002||Feb 1, 2005||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6875180||Feb 19, 2002||Apr 5, 2005||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6889092||Dec 28, 2001||May 3, 2005||Cardiac Pacemakers, Inc.||High impedance electrode assembly|
|US6901290||Feb 19, 2002||May 31, 2005||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6925328||Aug 2, 2001||Aug 2, 2005||Biophan Technologies, Inc.||MRI-compatible implantable device|
|US6954674||Feb 19, 2002||Oct 11, 2005||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US6968236||Jan 28, 2002||Nov 22, 2005||Biophan Technologies, Inc.||Ceramic cardiac electrodes|
|US6980848||May 2, 2005||Dec 27, 2005||Biopham Technologies Inc.||Optical MRI catheter system|
|US6981314||Jan 9, 2002||Jan 3, 2006||Advanced Neuromodulation Systems, Inc.||Method of forming a lead|
|US6988001||Oct 30, 2002||Jan 17, 2006||Biophan Technologies, Inc.||Hermetic component housing for photonic catheter|
|US6993387||Feb 19, 2002||Jan 31, 2006||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US7010357||Feb 19, 2002||Mar 7, 2006||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US7013174||Feb 19, 2002||Mar 14, 2006||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US7047074||Feb 19, 2002||May 16, 2006||Biophan Technologies, Inc.||Electromagnetic interference immune tissue invasive system|
|US7047627||Aug 3, 2005||May 23, 2006||Advanced Neuromodulation Systems, Inc.||Method for fabricating an implantable apparatus for delivering electrical stimulation from a pulse generator|
|US7054686||Sep 13, 2002||May 30, 2006||Biophan Technologies, Inc.||Pulsewidth electrical stimulation|
|US7139608||Jul 31, 2002||Nov 21, 2006||Uab Research Foundation||Pacing methods and devices using feedback controlled timing|
|US7139610 *||Apr 26, 2002||Nov 21, 2006||Medtronic, Inc.||Capture management in multi-site pacing|
|US7162298||Sep 10, 2002||Jan 9, 2007||Uab Research Foundation||Devices for detecting the presence of cardiac activity following administration of defibrillation therapy|
|US7450996||Oct 22, 2004||Nov 11, 2008||Medtronic, Inc.||Medical device with an electrically conductive anti-antenna geometrical shaped member|
|US7522958||Mar 13, 2003||Apr 21, 2009||Uab Research Foundation||Methods and systems for reducing discomfort from cardiac defibrillation shocks|
|US7734344||Dec 2, 2003||Jun 8, 2010||Uab Research Foundation||Methods, systems and computer program products to inhibit ventricular fibrillation during cardiopulmonary resuscitation|
|US8316537||Dec 4, 2009||Nov 27, 2012||Advanced Neuromodulation Systems, Inc.||Method of forming a lead|
|US8346339||Mar 1, 2012||Jan 1, 2013||Topera, Inc.||Basket style cardiac mapping catheter having a flexible electrode assembly for detection of cardiac rhythm disorders|
|US8364234||Mar 1, 2012||Jan 29, 2013||Topera, Inc.||Basket style cardiac mapping catheter having spline bends for detection of cardiac rhythm disorders|
|US8364235||Mar 1, 2012||Jan 29, 2013||Topera, Inc.||Basket style cardiac mapping catheter having an atraumatic basket tip for detection of cardiac rhythm disorders|
|US8364236||Mar 1, 2012||Jan 29, 2013||Topera, Inc.||Flexible electrode assembly for insertion into body lumen or organ|
|US8504133||Nov 28, 2012||Aug 6, 2013||Topera, Inc.||Basket style cardiac mapping catheter having a flexible electrode assembly and an atraumatic tip for detection of cardiac rhythm disorders|
|US8527046||Sep 21, 2004||Sep 3, 2013||Medtronic, Inc.||MRI-compatible implantable device|
|USRE32204 *||Jun 1, 1983||Jul 15, 1986||Mansfield Scientific, Inc.||Electrode assembly for temporary pacing and heart measurements|
|DE2929498A1 *||Jul 20, 1979||Jan 31, 1980||Medtronic Inc||Implantierbares elektronisches geraet|
|EP0159753A1 *||Apr 4, 1985||Oct 30, 1985||Eliezer A. Astrinski||Cardiac lead|
|EP0661078A2 *||Dec 28, 1994||Jul 5, 1995||Ventritex, Inc.||Cardiac defibrillation lead having defibrillation and atrial sensing electrodes|
|WO1998036794A1 *||Feb 16, 1998||Aug 27, 1998||Luciano Alcidi||A single electrical catheter for sequential cardiac stimulation|
|WO1999011320A1||Jun 1, 1998||Mar 11, 1999||Medtronic Inc||Single pass lead and method of use|
|WO2012170258A1 *||May 30, 2012||Dec 13, 2012||Curtis Guy P||System and method for transvascular activation of cardiac nerves with automatic restart|
|Apr 9, 1985||AS||Assignment|
Owner name: TELECTRONICS PTY. LIMITED
Free format text: CONFIRMS THE GRANTING OF LICENSE AGREEMENT DATED JULY 1, 1973 SUBJECT TO CONDITIONS IN AGREEMENT DATED JANUARY 16, 1984;ASSIGNOR:HONEYWELL MEDICAL ELECTRONICS B.V.;REEL/FRAME:004436/0297
Effective date: 19850306
|Apr 3, 1981||AS||Assignment|
Owner name: COOK PACEMAKER CORPORATION, P.O. BOX 99, BLOOMINGT
Free format text: LICENSE;ASSIGNOR:ATLANTIC RICHFIELD COMPANY;REEL/FRAME:003852/0285
Effective date: 19810327
Owner name: COOK PACEMAKER CORPORATION, INDIANA