|Publication number||US3839741 A|
|Publication date||Oct 8, 1974|
|Filing date||Nov 17, 1972|
|Priority date||Nov 17, 1972|
|Publication number||US 3839741 A, US 3839741A, US-A-3839741, US3839741 A, US3839741A|
|Original Assignee||Haller J|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (3), Non-Patent Citations (1), Referenced by (230), Classifications (10)|
|External Links: USPTO, USPTO Assignment, Espacenet|
[451 Oct. 8, 1974"  HEART VALVE AND RETAINING MEANS THEREFOR  Inventor: Jordan D. Haller, 2701 W.
. Alameda, Burbank, Calif. 91505  Filed: Nov. 17,1972  Appl. No.: 307,351
 US. Cl 3/1, 3/DIG. 3,"l37/512.2,
 References Cited UNITED STATESPATENTS 3,378,029 4/1968 Lee 3,579,642 5/1971 Heffernan et al 3/1 FOREIGN PATENTS OR APPLICATIONS 482,441 12/1969 Switzerland 3/DlG. 3
OTHER PUBLICATIONS The In Vivo Comparison of Hemodynamic Function of Ball, Disk, and Eccentric Monocusp Artificial Mitral Valves, by R. W. M. Frater et al., Prosthetic Heart Valves, (Book), Charles C. Thomas, publisher,
1 1968, pages 262-277.
Primary Examiner-Richard A. Gaudet Assistant Examiner-Ronald L. Frinks Attorney, Agent, or Firm-Larson, Taylor and Hinds [5 7] ABSTRACT An arrangement for retaining a heart valve in a passageway of a cardiovascular system, and a heart valve useable therewith. The retaining arrangement includes an annular arrangement surrounding the circular heart valve and engaging it so as to be radially expandable and cont'ractable relative thereto while securely holding the heart valve in place. The annular arrangement may include a single overlapping loop or a plurality of arcuate segments, all of which could slidingly engage a circumferentially extending flange on the outside of the heart valve. The heart valve includesa plurality of circular elements interfitting in a single plane to close the valve and extending axially relative to each other to open the valve and hence permit fluid flow through the passageway.
PATENTEB UB7 3 i 74 SREUIBF 3 Fla. 5
HEART VALVE AND RETAINING MEANS THEREFOR BACKGROUND OF THE INVENTION This invention relates to a prosthetic device, and in particular it relates to a valve structure useable as a heart valve; and this invention also relates to a retaining means for adjustably securing a heart valve in a passageway of a cardiovascular system.
'Many forms of heart valves are currently known and used. For example, one such device is shown in the Lee U.S. Pat. No. 3,378,029, which shows a heart valve having a plurality of nested circular elements. However, in view of the extremely specialized and highly delicate nature of the use to which a heart valve is put, there is a continuing need for new and improved valve structures therefor.
Heart valves generally include a substantially fixed outer support part to which a suitable fabric such as a Dacron or Teflon fabric is attached, this fabric serving as the means for connecting the heart valve to the walls of the passageway. However, while these support parts have generally been fixed elements, the systems in which they are used are dynamic parts, i.e., passages in the heart which expand and contract each time that the heart beats. Also, the heart shrinks in size following reparative surgery. This conflict between the dynamic nature of the cardiovascular system and the static nature of the conventional heart valve support means creates problems, the solutions to which the present invention is directed.
SUMMARY OF THE INVENTION Thus, it is a purpose of this invention to provide a new and improved prosthetic structure for the cardiovascular system which improves upon and solves problems associated with structures known heretofore.
The present invention provides a new and improved means for retaining a heart valve of the construction in the passageway of a cardiovascular system. According to the invention, the connecting means is an annular arrangement surrounding the heart valve and so connected to the heart valve that it is permitted to expand and contract radially while at the same time it is capable of being positively secured to the walls of the passageway. A cloth is connected to the outer periphery of the annular arrangement and the cloth is sutured to the walls of the passageway.
Within this basic structure, the annular arrangement can have many different forms. The heart valve will preferably have formed on the outer circumference thereof an outwardly extending circumferential flange to which the annular arrangement would be attached for sliding movement both circumferentially therealong and radially relative thereto. In a preferred embodiment, the annular arrangement will comprise a plurality of arcuate segments, each having a slot on its inner periphery to engage said flange. Of course a circumferential space will be provided between adjacent segments permitting them to move radially relative to the heart valve. The segments may be interconnected circumferentially by means which permit relative circumferential sliding movement or the circumferential engagement of the segments may simply be provided by the cloth fabric referred to above which will extend in a continuous circle all about the outer periphery of the annular arrangement. The cloth should have a degree of elasticity so that it could stretch and relax circumferentially as the segments moved radially outwardly and inwardly respectively.
In another embodiment, the annular arrangement may take the form of a single loop which overlaps itself and is thus capable of increasing and decreasing the extent of overlap so as to expand and contract radially relative to the heart valve.
With the above described heart valve retaining means, it is now possible to secure the heart valve in place during the operative procedure, after which the overall dimensions of the heart valve (i.e., the heart valve and its retaining means) will shrink in size concurrently as the heart shrinks in size following surgery. This has the advantage of minimizing pressure on the conduction system on the heart and thus reducing the possibility of subsequent arrhythmias. In addition, this will minimize the possibility of the sutures tearing out by the gradual shrinkage of the heart, which might be the case if the overall heart valve structure were completely fixed relative to the dynamic, shrinking heart. Further, the normal action of the heart includes expansion and contraction and by allowing motion of the valve during this normal cardiac cycle, the possibility is reduced of the sutures tearing out until such time as the valve is anchored to the passage walls by the ingrowth of fibrous tissues.
While the heart valve retaining means is usable with essentially any type of heart valve, the present invention also provides a new and improved heart valve structure capable of being used in combination with the new and improved annular retaining means or separately therefrom.
According to the preferred embodiment, this new heart valve structure comprises a plurality of circular and ring shaped segments which, in the closed condition interfit with each other in a single plane, and which in an expanded condition separate from each other axially to an extent permitted by retaining struts to permit fluid to low therethrough. This structure provides several advantages. First, in the closed condition the valve is rather compact since all'elements lie in a single plane. Secondly, the structure is such that a good seal may be formed between the individual. elements of the valve in the closed condition. Further, in the open condition the elements can separate from each other a relatively large distance, thus permitting free flow of fluid therethrough. Moreover, the valve structure provides a unique combination of ruggedness and flexibility. This is so because the individual valve elements are plates which can be formed of a strong metal material containing the retaining struts to interconnect them in the open condition, and the various ring elements can turn out of their normal transverse planes, thus permitting a certain degree of flexibility. In a preferred arrangeand improved prosthetic device for the cardiovascular system.
It is another object of this invention to provide a new and improved heart valve retaining means which is capable of undergoing radial expansion and contraction.
It is still another object of this invention to prov de a new and improved valve retaining means having a plurality of arcuate segments arranged annularly around the valve for connecting the valve to the passageway in the cardiovascular system, the annular arrangement being movable radially.
It is another object of this invention to provide a new and improved heart valve having a plurality of circular or ring shaped elements which, in the closed position, lie in a common plane, and which in the open position, separate axially from each other to an extent permitted by struts.
It is still another object of this invention to provide a new and improved heart valve having a plurality of circular or ring shaped elements movable between an open position. and a closed position in combination with a radially adjustable annulus for connecting the heart valve to the passageway of the cardiovascular system.
Other objects and the advantages of the invention will become apparent from the detailed description to follow together with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS There follows a detailed description. of preferred embodiments which are to be read together with the accompanying drawings.
FIG. 1 is a plan view of a heart valve constructed in accordance with the present invention in combination with an adjustable annular retaining means therefor.
FIG. 2 is a cross-sectional view taken along line 22 of FIG. 1.
FIG. 3 is a cross-sectional view similar to FIG. 2 but showing the valve elements in the valve-opened condition and excluding the adjustable annular retaining structure.
FIG. 4 is an enlarged, long line 44 of FIG. 2.
FIG. 5 is a cross-sectional view similar to the righthand side of FIG. 2 but showing a modification of the invention.
FIG. 6 is a plan view showing a portion of a modified annular valve retaining means.
FIG. 7 is a cross-sectional view taken along line 7-7 of FIG. 6.
FIG. 8 is a perspective view of an elementof FIGS. 6 and 7.
FIG. 9 is a plan view similar to FIG. 1 but omitting the valve itself and showing a modified structure of the annular valve retaining means.
FIG. 10 is a perspective view of an element of FIG.
partial sectional view taken FIG. 11 is a plan view similar to FIG. 1 but omitting the valve structure and showing a modification of the annular valve retaining means.
FIG. 12 is a cross-sectional view taken along line 12-12 of FIG. 11.
DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring now to the drawings, like elements are represented by like numerals throughout the several views.
FIGS. 14 show a heart valve assembly 10 having a heart valve 11 in combination with an expandable annular retaining means 12.
Referring in particular to FIGS; 2 and 3, the heart valve 11 comprises acylindrical outer ring 13, intermediate annular rings 14 and 15, and an inner circular element 16. Each of elements l4, l5 and 16 have a bevelled frusto-conical outwardly facing surface 17 and each of elements 13, 14 and 15 have inwardly facing frustro-conical surfaces 18. As is apparent in FIG. 2, in the closed condition of the valve, facing surfaces 17 and 18 engage each other to seal the passageway in which the valve is located. Each one of the elements 13, 14 and 15 includes a lower annular shoulder 19. In turn, each of the elements 14, 15 and 16 has fixed thereto a plurality of struts 20, 22, and 23, respectively, which struts extend downwardly from the element with which it is connected and then outwardly as shown at 21 for the righthand element 20 in FIGS. 2 and 3 to engage the shoulder 19 of the element immediately be neath it. In this manner, the struts limit the upward and hence the opening movement of the valve.
In practice, the valve must of course assume any orientation and of course it does not depend on gravity to open and close. In practice, pressure on the upstream side of the valve (the lower part in FIGS. 2 and 3) would open the valve, and then a pressure differential in the opposite direction during another part of the car diac cycle wouldclose the valve.
In FIG. 2, the walls of the passageway in which the valve is located is designated by 25. In FIG. 2, the flow would be in the upward direction. Referring now to FIGS. 1, 2 and 4, the valve is secured in the passageway 25 by the adjustable annular retaining means in the following manner. A flange 30 projects outwardly from the outer ring 13 and extends continuously around the valve and includes an upwardly extending lip 31. In this embodiment, the annular retaining means comprises a plurality of arcuate segments 32, each of which includes an inner cavity 33 for receiving the lip 31 of the flange 30 in such a manner that the segment 32 can move radially relative to the flange 30. The segment 32 also includes an outer element 34, the purpose of which is to secure to the segment 32 a clock 35 of fabric or the like. As shown in FIG. 1, this cloth 35 will extend circumferentially completely around the annular retaining means 13, even across the spaces between adjacent segments. The annular retaining means 12 is then connected to wall 25 by means of sutures secured to the fabric 35 in a manner known per se, and it also extends from wall 25 radially inwardly to completely cover the means 12. It is connected above to the outside of ring 13 and below to the radial inner side of bottom wall 39.
The segments 32 are probably adequately supported in all directions by their engagement with the flange 30 and lip 31. However, to further guide these elements 32 in their relative movement, guiding means 36-38 may be provided. This guiding means includes an elongated hollow slot 36 attached to each segment 32, each slot 36 having fixed thereto a rod 37 extending into the slot 36 of the adjacent segment and including at its end a head 38 engageable in said adjacent slot 36. See FIG. 4.
Means must be provided for preventing fluid flow through the expandable annular retaining means when the valve is in the closed position, i.e., around the flange 30 or between the segments 32. For this purpose, a suitable flexible waterproof material can be connected to the two facing ends of adjacent segments 32 and also from the lower end of element 13 across to the bottom wall 39 of the segment 32 as shown at 43 in FIG. 2. In lieu of element 43, the flange 30 can of course engage the bottom wall 39 in a tight watertight manner.
FIG. 5 shows a modification of the invention wherein the flange 30 is replaced by a spring loaded flange 40 which has a lower portion spring biassed downwardly against bottom wall 39 at point 41. This provides a scraping action of the bottom wall 39 and prevents thrombus formation of the components until final closure is established. In addition, this can of course provide the fluid tight seal preventing fluid to flow through the annular retaining means 12 when the valve is in-the closed position.
FIGS. 6-8 show another modification of the annular retaining means 12. In this case, only the outer ring 13 of the valve 11 is shown and the flange 30 is replaced by a simple flange 45 which does not have a lip 31. In this embodiment, each of the arcuate segments 46 include a rod 47 integral therewith and projecting circumferentially therefrom and having at its outer end an enlarged head 48. On its opposite circumferential side, the segment 46 includes an opening 49 large enough to receive rod 47, but not large enough to receive head 48. On its radial inner side, the segment 46 includes a slot 50 adapted to receive the flange 45. In the same manner as in the embodiment of FIGS. 1-5, a fabric material such as Dacron or Teflon surrounds and is attached to the outer periphery of the segments 46 for attaching the valve means to the wells of passageway 25.
The embodiment of FIGS. 9-10 is similar to the embodiment of FIGS. 6-8 except that the shape of the individual segments is somewhat changed. In this case, the arcuate segments 55 are cylindrical and include at one end a circular arcuate rod 56 which does not have an enlarged head but which is adapted to fit through the opening 57 on the adjacent arcuate segment. Slot 58 is provided on the radial inner facing surface to engage flange 45, and a fabric ring surrounds the outer periphery of the segments 55.
In the embodiment of FIGS. 11 and 12, a single element 65 extends completely around the valve means and overlaps itself loosely through a harness 67 which permits the element 65 to decrease and increase its overlap, thus expanding and contracting, radially, respectively. A plurality of inwardly facing slots 66 engage flange 45 and a fabric ring 68 completely surrounds the element 65 for attaching the same to the walls of passage 25.
In all of the embodiments, it will therefore be seen that the expandable annular retaining means 12 is capable of limited radial expansion and contraction relative to the valve member itself. Thus, in operation the valve with an adjustable annular retaining means can be inserted into a passage in the cardiovascular system during which time the passage will be enlarged. Then, following surgery, as the passage shrinks, the annular retaining means will also contract, moving inwardly as the individual segments move closer together. For example, in the embodiment of FIGS. 1 and 2, the means 12 is shown in its radial outer position. Note the space A between the lip 31 and the outer side of cavity 33 and a similar space B between the inner wall of cavity 33 and the element 13. Also not in FIG. 1 that the segments 32 are spaced apart from each other circumferentially. The assembly might be installed in the passageway 25 in this manner. Then, in the course of time, the passageway 25 would shrink and the means 12 would move radially inwardly, the cavities 33 moving in on the flange 30 as the spaces A and B reduce in size. Thus, contrary to the prior art wherein such shrinkage would cause a stress where the wall engaged the support, in this case the wall can simply shrink, moving with it the valve retaining means. The valve retaining means would be so dimensioned that even after shrinkage had been completed, the spaces A and B would not be completely eliminated, i.e., the element 13 would not touch the element 33. This would leave some leeway for the means 12 to expand and contract as the passageway 25 expanded and contracted during the normal cardiac cycle without tearing the valve from its sutures anchoring the fabric 35 to the walls of passageway 25.
In the preferred embodiment of the valve 11, the structural elements 13, 14, 15 and 16 would be made entirely of steel containing struts. In a normal useage of the present invention, a total change in diameter of approximately three to four millimeters would be sufficient for preventing the sutures from being torn.
Although the invention has been described in considerable detail with respect to preferred embodiments thereof, it will be apparent that the invention is capable of numerous modifications and variations apparent to those skilled in the art without departing from the spirit and scope of the invention.
1. In combination, a valve means and a valve retaining means for securing the valve means to the internal walls of a passageway in a cardiovascular system as a prosthetic replacement in the cardiovascular system, said valve means being movable between open and closed positions and including fixed external means at the outer periphery thereof; said retainer means including an annular arrangement surrounding the valve means and including at least one stiff element operatively engaging the external means of the valve means, at least one of said external means and stiff element having slot means therein slidably engaging the other for radial movement relative thereto, the retainer means thus being expandable and contractable relative to the valve means transversely of the direction of fluid flow in the passageway as the passageway enlarges and contracts.
2. The invention according to claim 1, said retainer means comprising-a single element surrounding the valve means and overlapping itself circumferentially.
3. The invention according to claim 2, said single element including at least one slot on the radial inner side thereof and a radially outwardly extending circumferential flange on the outer wall of the valve means engaging said at least one slot so as to permit sliding radial movement of the single element relative to the flange.
6. The invention according to claim 5, wherein said flange'includes a spring means for urging said flange into engagement with the walls of the slots.
7. The invention according to claim 1, including a ring of fabric material surrounding the annular arrangement and adapted to be connected to the said passageway in the cardiovascular system.
8. The invention according to claim 1, said retaining means including a plurality of arcuately extending segments engaging the valve means for said radial sliding movement relative thereto.
9. The invention according to claim 8, said segments including a radial inner cavity having a radially inwardly opening slot slidingly engaging a circumferential flange on the valve means and an outer part adapted to secure thereto a fabric ring.
10. The invention according to claim 8, said segments being slidingly connected to each other circumferentially such that they can move circumferentially relative to each other as well as radially relative to the valve means.
1 l. The invention according to claim 8, each segment having an opening at one circumferential end thereof and a rod extending from the other circumferential end thereof, the rods slidingly interfitting into openings in the respective adjacent segment.
12. The invention according to claim 11, the segments, viewed in a radial plane, being essentially circular.
13. The invention accordng to, claim 11, the segments, viewed in a radial plane, being essentially rectangular.
14. A valve adapted to be used as a replacement for a valve in a cardiovascular system comprising a valve body including a plurality of concentric ring shaped elements having inner and outer bevelled outer surface and a ring shaped outer ring element having a bevelled inner surface, said circular inner element, said ring shaped elements and said ring shaped outer element interfitting to lie in a common plane when the valve is closed, struts on each of said ring shaped elements and said inner circular element having bent outer ends to engage the adjacent element to limit the separation of said elements when the valve is opened, and a radially expandable contractable annular retainer means comprising at least one stiff segment arranged in an annulus around the valve body and having an inner cavity formed thereon with a radially inwardly facing slot in said cavity and a stiff flange means on said ring shaped outer element slidably engaging in said slot.
15. A valve accordng to claim 14, wherein said flange means includes spring means for urging said means into engagement with the walls of the slots.
16. A valve according to claim 14, including a plurality of said segments arranged annularly about the valve. l l
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3378029 *||Nov 23, 1965||Apr 16, 1968||Lucas Industries Ltd||Nested ring valve|
|US3579642 *||Apr 15, 1968||May 25, 1971||Heffernan Bart T||Heart valve assembly and method of implanting in the body|
|CH482441A *||Title not available|
|1||*||The In Vivo Comparison of Hemodynamic Function of Ball, Disk, and Eccentric Monocusp Artificial Mitral Valves, by R. W. M. Frater et al., Prosthetic Heart Valves, (Book), Charles C. Thomas, publisher, 1968, pages 262 277.|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US4030142 *||Mar 26, 1976||Jun 21, 1977||Intermed, Inc.||Occluder for prosthetic heart valve assembly|
|US4038703 *||Nov 14, 1975||Aug 2, 1977||General Atomic Company||Prosthetic devices having a region of controlled porosity|
|US4055861 *||Apr 9, 1976||Nov 1, 1977||Rhone-Poulenc Industries||Support for a natural human heart valve|
|US4345340 *||May 7, 1981||Aug 24, 1982||Vascor, Inc.||Stent for mitral/tricuspid heart valve|
|US4743253 *||Mar 4, 1986||May 10, 1988||Magladry Ross E||Suture rings for heart valves and method of securing same to heart valves|
|US5176171 *||Oct 17, 1991||Jan 5, 1993||Flomatic Corporation||Check valve|
|US5607470 *||May 1, 1995||Mar 4, 1997||Milo; Simcha||Suture rings for prosthetic heart valves|
|US5788689 *||Jan 31, 1996||Aug 4, 1998||St. Jude Medical, Inc.||Prosthetic heart valve rotator tool|
|US5824068 *||Aug 7, 1997||Oct 20, 1998||St. Jude Medical, Inc.||Cardiac valve holders|
|US5876436 *||Feb 13, 1997||Mar 2, 1999||St. Jude Medical, Inc.||Rotatable cuff assembly for a heart valve prosthesis|
|US6126007 *||Dec 30, 1998||Oct 3, 2000||St. Jude Medical, Inc.||Tissue valve holder|
|US6174332||Dec 5, 1997||Jan 16, 2001||St. Jude Medical, Inc.||Annuloplasty ring with cut zone|
|US6319281 *||Mar 22, 1999||Nov 20, 2001||Kumar R. Patel||Artificial venous valve and sizing catheter|
|US6358278||Sep 24, 1999||Mar 19, 2002||St. Jude Medical, Inc.||Heart valve prosthesis with rotatable cuff|
|US6454799||Apr 6, 2000||Sep 24, 2002||Edwards Lifesciences Corporation||Minimally-invasive heart valves and methods of use|
|US6613085||Sep 26, 1997||Sep 2, 2003||St. Jude Medical, Inc.||Prosthetic heart valve rotator tool|
|US6767362||Jun 28, 2002||Jul 27, 2004||Edwards Lifesciences Corporation||Minimally-invasive heart valves and methods of use|
|US7186265||Dec 3, 2004||Mar 6, 2007||Medtronic, Inc.||Prosthetic cardiac valves and systems and methods for implanting thereof|
|US7201771||Dec 26, 2002||Apr 10, 2007||Arbor Surgical Technologies, Inc.||Bioprosthetic heart valve|
|US7329279||Jul 15, 2004||Feb 12, 2008||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US7381218||Jan 28, 2004||Jun 3, 2008||Edwards Lifesciences Corporation||System and method for implanting a two-part prosthetic heart valve|
|US7381219||Dec 23, 2003||Jun 3, 2008||Sadra Medical, Inc.||Low profile heart valve and delivery system|
|US7445631||Jul 15, 2004||Nov 4, 2008||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US7503930||Feb 16, 2007||Mar 17, 2009||Medtronic, Inc.||Prosthetic cardiac valves and systems and methods for implanting thereof|
|US7513909||Apr 10, 2006||Apr 7, 2009||Arbor Surgical Technologies, Inc.||Two-piece prosthetic valves with snap-in connection and methods for use|
|US7524331||Apr 6, 2006||Apr 28, 2009||Medtronic Vascular, Inc.||Catheter delivered valve having a barrier to provide an enhanced seal|
|US7530997 *||Jan 21, 2005||May 12, 2009||Advanced Surgical Design And Manufacture Limited||Heart valve|
|US7544206||Jul 19, 2004||Jun 9, 2009||Medtronic, Inc.||Method and apparatus for resecting and replacing an aortic valve|
|US7591848||Apr 6, 2006||Sep 22, 2009||Medtronic Vascular, Inc.||Riveted stent valve for percutaneous use|
|US7611535||Nov 3, 2009||Medtronic, Inc.||Fixation band for affixing a prosthetic heart valve to tissue|
|US7625403||Apr 4, 2006||Dec 1, 2009||Medtronic Vascular, Inc.||Valved conduit designed for subsequent catheter delivered valve therapy|
|US7682390||Jul 30, 2002||Mar 23, 2010||Medtronic, Inc.||Assembly for setting a valve prosthesis in a corporeal duct|
|US7708775||May 24, 2006||May 4, 2010||Edwards Lifesciences Corporation||Methods for rapid deployment of prosthetic heart valves|
|US7712606||Feb 2, 2006||May 11, 2010||Sadra Medical, Inc.||Two-part package for medical implant|
|US7717955||Feb 28, 2005||May 18, 2010||Medtronic, Inc.||Conformable prosthesis for implanting two-piece heart valves and methods for using them|
|US7727276 *||Apr 4, 2007||Jun 1, 2010||Machiraju Venkat R||System and method for heart valve replacement|
|US7740655||Apr 6, 2006||Jun 22, 2010||Medtronic Vascular, Inc.||Reinforced surgical conduit for implantation of a stented valve therein|
|US7748389||Oct 21, 2004||Jul 6, 2010||Sadra Medical, Inc.||Leaflet engagement elements and methods for use thereof|
|US7758606||Feb 5, 2004||Jul 20, 2010||Medtronic, Inc.||Intravascular filter with debris entrapment mechanism|
|US7758640 *||Jul 20, 2010||Valvexchange Inc.||Cardiovascular valve assembly|
|US7776083||Dec 28, 2005||Aug 17, 2010||The Cleveland Clinic Foundation||Bioprosthetic cardiovascular valve system|
|US7780725||Jun 16, 2004||Aug 24, 2010||Sadra Medical, Inc.||Everting heart valve|
|US7780726||Aug 24, 2010||Medtronic, Inc.||Assembly for placing a prosthetic valve in a duct in the body|
|US7819915||Oct 26, 2010||Edwards Lifesciences Corporation||Heart valve holders and handling clips therefor|
|US7824442||Nov 2, 2010||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US7824443||Feb 2, 2006||Nov 2, 2010||Sadra Medical, Inc.||Medical implant delivery and deployment tool|
|US7871436||Jan 18, 2011||Medtronic, Inc.||Replacement prosthetic heart valves and methods of implantation|
|US7892281||Feb 22, 2011||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US7914569||May 13, 2005||Mar 29, 2011||Medtronics Corevalve Llc||Heart valve prosthesis and methods of manufacture and use|
|US7951197||May 31, 2011||Medtronic, Inc.||Two-piece prosthetic valves with snap-in connection and methods for use|
|US7959666||Jun 14, 2011||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US7959672||Jun 14, 2011||Sadra Medical||Replacement valve and anchor|
|US7959674||Jun 14, 2011||Medtronic, Inc.||Suture locking assembly and method of use|
|US7967857||Jun 28, 2011||Medtronic, Inc.||Gasket with spring collar for prosthetic heart valves and methods for making and using them|
|US7972377||Aug 29, 2008||Jul 5, 2011||Medtronic, Inc.||Bioprosthetic heart valve|
|US7972378||Jul 5, 2011||Medtronic, Inc.||Stents for prosthetic heart valves|
|US7981153 *||Jul 19, 2011||Medtronic, Inc.||Biologically implantable prosthesis methods of using|
|US7988724||Aug 2, 2011||Sadra Medical, Inc.||Systems and methods for delivering a medical implant|
|US8002826||Oct 14, 2009||Aug 23, 2011||Medtronic Corevalve Llc||Assembly for placing a prosthetic valve in a duct in the body|
|US8016877||Jun 29, 2009||Sep 13, 2011||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US8021161||May 1, 2006||Sep 20, 2011||Edwards Lifesciences Corporation||Simulated heart valve root for training and testing|
|US8021421||Sep 20, 2011||Medtronic, Inc.||Prosthesis heart valve fixturing device|
|US8025695 *||Sep 27, 2011||Medtronic, Inc.||Biologically implantable heart valve system|
|US8048153||Nov 1, 2011||Sadra Medical, Inc.||Low profile heart valve and delivery system|
|US8052749||Nov 8, 2011||Sadra Medical, Inc.||Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements|
|US8052750||Nov 8, 2011||Medtronic Ventor Technologies Ltd||Valve prosthesis fixation techniques using sandwiching|
|US8070801||Dec 6, 2011||Medtronic, Inc.||Method and apparatus for resecting and replacing an aortic valve|
|US8075615||Dec 13, 2011||Medtronic, Inc.||Prosthetic cardiac valve formed from pericardium material and methods of making same|
|US8083793||Dec 27, 2011||Medtronic, Inc.||Two piece heart valves including multiple lobe valves and methods for implanting them|
|US8092487||Jan 10, 2012||Medtronic, Inc.||Intravascular filter with debris entrapment mechanism|
|US8092518||Jan 10, 2012||Edwards Lifesciences Corporation||Methods of implanting two-part heart valves|
|US8109996||Feb 7, 2012||Sorin Biomedica Cardio, S.R.L.||Minimally-invasive cardiac-valve prosthesis|
|US8136659||May 10, 2010||Mar 20, 2012||Sadra Medical, Inc.||Two-part package for medical implant|
|US8157852||Jan 22, 2009||Apr 17, 2012||Medtronic, Inc.||Delivery systems and methods of implantation for prosthetic heart valves|
|US8157853||Apr 17, 2012||Medtronic, Inc.||Delivery systems and methods of implantation for prosthetic heart valves|
|US8163014||Apr 5, 2010||Apr 24, 2012||Medtronic, Inc.||Conformable prostheses for implanting two-piece heart valves and methods for using them|
|US8182528||Dec 23, 2003||May 22, 2012||Sadra Medical, Inc.||Locking heart valve anchor|
|US8211169||Jul 3, 2012||Medtronic, Inc.||Gasket with collar for prosthetic heart valves and methods for using them|
|US8226710||Mar 25, 2011||Jul 24, 2012||Medtronic Corevalve, Inc.||Heart valve prosthesis and methods of manufacture and use|
|US8231670||Jul 31, 2012||Sadra Medical, Inc.||Repositionable heart valve and method|
|US8241274||Aug 14, 2012||Medtronic, Inc.||Method for guiding a medical device|
|US8246678||Mar 9, 2007||Aug 21, 2012||Sadra Medicl, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US8252052||Aug 28, 2012||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US8287584||Nov 14, 2005||Oct 16, 2012||Sadra Medical, Inc.||Medical implant deployment tool|
|US8308798||Nov 13, 2012||Edwards Lifesciences Corporation||Quick-connect prosthetic heart valve and methods|
|US8313525||Nov 20, 2012||Medtronic Ventor Technologies, Ltd.||Valve suturing and implantation procedures|
|US8328868||Dec 11, 2012||Sadra Medical, Inc.||Medical devices and delivery systems for delivering medical devices|
|US8343213||Oct 21, 2004||Jan 1, 2013||Sadra Medical, Inc.||Leaflet engagement elements and methods for use thereof|
|US8348995||Jan 8, 2013||Medtronic Ventor Technologies, Ltd.||Axial-force fixation member for valve|
|US8348996||Mar 23, 2007||Jan 8, 2013||Medtronic Ventor Technologies Ltd.||Valve prosthesis implantation techniques|
|US8348998||Jan 8, 2013||Edwards Lifesciences Corporation||Unitary quick connect prosthetic heart valve and deployment system and methods|
|US8349003||Apr 12, 2011||Jan 8, 2013||Medtronic, Inc.||Suture locking assembly and method of use|
|US8366769||Mar 17, 2004||Feb 5, 2013||Edwards Lifesciences Corporation||Low-profile, pivotable heart valve sewing ring|
|US8414643||Apr 9, 2013||Medtronic Ventor Technologies Ltd.||Sinus-engaging valve fixation member|
|US8430927||Feb 2, 2009||Apr 30, 2013||Medtronic, Inc.||Multiple orifice implantable heart valve and methods of implantation|
|US8449625||May 28, 2013||Edwards Lifesciences Corporation||Methods of measuring heart valve annuluses for valve replacement|
|US8460373||Jul 1, 2011||Jun 11, 2013||Medtronic, Inc.||Method for implanting a heart valve within an annulus of a patient|
|US8500798||May 24, 2006||Aug 6, 2013||Edwards Lifesciences Corporation||Rapid deployment prosthetic heart valve|
|US8500802||Mar 8, 2011||Aug 6, 2013||Medtronic, Inc.||Two-piece prosthetic valves with snap-in connection and methods for use|
|US8506625||Aug 9, 2010||Aug 13, 2013||Edwards Lifesciences Corporation||Contoured sewing ring for a prosthetic mitral heart valve|
|US8512397||Apr 27, 2009||Aug 20, 2013||Sorin Group Italia S.R.L.||Prosthetic vascular conduit|
|US8535373||Jun 16, 2008||Sep 17, 2013||Sorin Group Italia S.R.L.||Minimally-invasive cardiac-valve prosthesis|
|US8539662||Jun 16, 2008||Sep 24, 2013||Sorin Group Italia S.R.L.||Cardiac-valve prosthesis|
|US8540768||Dec 30, 2011||Sep 24, 2013||Sorin Group Italia S.R.L.||Cardiac valve prosthesis|
|US8551162||Dec 20, 2002||Oct 8, 2013||Medtronic, Inc.||Biologically implantable prosthesis|
|US8562672||Nov 18, 2005||Oct 22, 2013||Medtronic, Inc.||Apparatus for treatment of cardiac valves and method of its manufacture|
|US8574257||Aug 10, 2009||Nov 5, 2013||Edwards Lifesciences Corporation||System, device, and method for providing access in a cardiovascular environment|
|US8579962||Dec 20, 2005||Nov 12, 2013||Sadra Medical, Inc.||Methods and apparatus for performing valvuloplasty|
|US8579966||Feb 4, 2004||Nov 12, 2013||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US8591570||Mar 14, 2008||Nov 26, 2013||Medtronic, Inc.||Prosthetic heart valve for replacing previously implanted heart valve|
|US8603159||Dec 11, 2009||Dec 10, 2013||Medtronic Corevalve, Llc||Prosthetic valve for transluminal delivery|
|US8603160||Dec 23, 2003||Dec 10, 2013||Sadra Medical, Inc.||Method of using a retrievable heart valve anchor with a sheath|
|US8603161||Jul 6, 2009||Dec 10, 2013||Medtronic, Inc.||Attachment device and methods of using the same|
|US8617236||Nov 2, 2011||Dec 31, 2013||Sadra Medical, Inc.||Medical devices and delivery systems for delivering medical devices|
|US8623076||Sep 22, 2011||Jan 7, 2014||Sadra Medical, Inc.||Low profile heart valve and delivery system|
|US8623077||Dec 5, 2011||Jan 7, 2014||Medtronic, Inc.||Apparatus for replacing a cardiac valve|
|US8623078||Jun 8, 2011||Jan 7, 2014||Sadra Medical, Inc.||Replacement valve and anchor|
|US8623080 *||Sep 22, 2011||Jan 7, 2014||Medtronic, Inc.||Biologically implantable prosthesis and methods of using the same|
|US8628570||Aug 18, 2011||Jan 14, 2014||Medtronic Corevalve Llc||Assembly for placing a prosthetic valve in a duct in the body|
|US8641757||Jun 23, 2011||Feb 4, 2014||Edwards Lifesciences Corporation||Systems for rapidly deploying surgical heart valves|
|US8652204||Jul 30, 2010||Feb 18, 2014||Medtronic, Inc.||Transcatheter valve with torsion spring fixation and related systems and methods|
|US8668733||Nov 12, 2008||Mar 11, 2014||Sadra Medical, Inc.||Everting heart valve|
|US8673000||May 20, 2011||Mar 18, 2014||Medtronic, Inc.||Stents for prosthetic heart valves|
|US8685077||Mar 14, 2012||Apr 1, 2014||Medtronics, Inc.||Delivery systems and methods of implantation for prosthetic heart valves|
|US8685084||Dec 28, 2012||Apr 1, 2014||Sorin Group Italia S.R.L.||Prosthetic vascular conduit and assembly method|
|US8696742||Oct 10, 2012||Apr 15, 2014||Edwards Lifesciences Corporation||Unitary quick-connect prosthetic heart valve deployment methods|
|US8721708||Sep 23, 2011||May 13, 2014||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US8721714||Sep 17, 2008||May 13, 2014||Medtronic Corevalve Llc||Delivery system for deployment of medical devices|
|US8728155||Sep 20, 2013||May 20, 2014||Cephea Valve Technologies, Inc.||Disk-based valve apparatus and method for the treatment of valve dysfunction|
|US8747458||Aug 20, 2007||Jun 10, 2014||Medtronic Ventor Technologies Ltd.||Stent loading tool and method for use thereof|
|US8747460||Dec 23, 2011||Jun 10, 2014||Medtronic Ventor Technologies Ltd.||Methods for implanting a valve prothesis|
|US8747463||Aug 3, 2011||Jun 10, 2014||Medtronic, Inc.||Methods of using a prosthesis fixturing device|
|US8771302||Apr 6, 2007||Jul 8, 2014||Medtronic, Inc.||Method and apparatus for resecting and replacing an aortic valve|
|US8771345||Oct 31, 2011||Jul 8, 2014||Medtronic Ventor Technologies Ltd.||Valve prosthesis fixation techniques using sandwiching|
|US8771346||Jul 25, 2011||Jul 8, 2014||Medtronic Ventor Technologies Ltd.||Valve prosthetic fixation techniques using sandwiching|
|US8777980||Dec 23, 2011||Jul 15, 2014||Medtronic, Inc.||Intravascular filter with debris entrapment mechanism|
|US8801779||May 10, 2011||Aug 12, 2014||Medtronic Corevalve, Llc||Prosthetic valve for transluminal delivery|
|US8808369||Oct 5, 2010||Aug 19, 2014||Mayo Foundation For Medical Education And Research||Minimally invasive aortic valve replacement|
|US8821569||Apr 30, 2007||Sep 2, 2014||Medtronic, Inc.||Multiple component prosthetic heart valve assemblies and methods for delivering them|
|US8828078||Sep 20, 2005||Sep 9, 2014||Sadra Medical, Inc.||Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements|
|US8834563||Dec 16, 2009||Sep 16, 2014||Sorin Group Italia S.R.L.||Expandable prosthetic valve having anchoring appendages|
|US8834564||Mar 11, 2010||Sep 16, 2014||Medtronic, Inc.||Sinus-engaging valve fixation member|
|US8840661||May 13, 2009||Sep 23, 2014||Sorin Group Italia S.R.L.||Atraumatic prosthetic heart valve prosthesis|
|US8840662||Oct 27, 2011||Sep 23, 2014||Sadra Medical, Inc.||Repositionable heart valve and method|
|US8840663||Dec 23, 2003||Sep 23, 2014||Sadra Medical, Inc.||Repositionable heart valve method|
|US8845720||Sep 20, 2011||Sep 30, 2014||Edwards Lifesciences Corporation||Prosthetic heart valve frame with flexible commissures|
|US8858619||May 12, 2006||Oct 14, 2014||Medtronic, Inc.||System and method for implanting a replacement valve|
|US8858620||Jun 10, 2011||Oct 14, 2014||Sadra Medical Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US8870948||Jan 31, 2014||Oct 28, 2014||Cephea Valve Technologies, Inc.||System and method for cardiac valve repair and replacement|
|US8876894||Mar 23, 2007||Nov 4, 2014||Medtronic Ventor Technologies Ltd.||Leaflet-sensitive valve fixation member|
|US8876895||Mar 23, 2007||Nov 4, 2014||Medtronic Ventor Technologies Ltd.||Valve fixation member having engagement arms|
|US8876896||Dec 7, 2011||Nov 4, 2014||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US8894703||Jun 22, 2011||Nov 25, 2014||Sadra Medical, Inc.||Systems and methods for delivering a medical implant|
|US8911493||Jul 30, 2013||Dec 16, 2014||Edwards Lifesciences Corporation||Rapid deployment prosthetic heart valves|
|US8915959||Oct 23, 2001||Dec 23, 2014||Heartport, Inc.||Endovascular aortic valve replacement|
|US8920492||Aug 21, 2013||Dec 30, 2014||Sorin Group Italia S.R.L.||Cardiac valve prosthesis|
|US8925164||Sep 11, 2009||Jan 6, 2015||Valvexchange Inc.||Valve assembly with exchangeable valve member and a tool set for exchanging the valve member|
|US8940014||Nov 14, 2012||Jan 27, 2015||Boston Scientific Scimed, Inc.||Bond between components of a medical device|
|US8951243||Nov 29, 2012||Feb 10, 2015||Boston Scientific Scimed, Inc.||Medical device handle|
|US8951299||Oct 13, 2009||Feb 10, 2015||Sadra Medical, Inc.||Medical devices and delivery systems for delivering medical devices|
|US8956402||Sep 14, 2012||Feb 17, 2015||Medtronic, Inc.||Apparatus for replacing a cardiac valve|
|US8986329||Oct 28, 2013||Mar 24, 2015||Medtronic Corevalve Llc||Methods for transluminal delivery of prosthetic valves|
|US8986361||Oct 17, 2008||Mar 24, 2015||Medtronic Corevalve, Inc.||Delivery system for deployment of medical devices|
|US8986374||May 10, 2011||Mar 24, 2015||Edwards Lifesciences Corporation||Prosthetic heart valve|
|US8992608||Jun 26, 2009||Mar 31, 2015||Sadra Medical, Inc.||Everting heart valve|
|US8998976||Jul 12, 2012||Apr 7, 2015||Boston Scientific Scimed, Inc.||Coupling system for medical devices|
|US8998979||Feb 11, 2014||Apr 7, 2015||Medtronic Corevalve Llc||Transcatheter heart valves|
|US8998981||Sep 15, 2009||Apr 7, 2015||Medtronic, Inc.||Prosthetic heart valve having identifiers for aiding in radiographic positioning|
|US9005273||Apr 4, 2007||Apr 14, 2015||Sadra Medical, Inc.||Assessing the location and performance of replacement heart valves|
|US9005277||Dec 21, 2012||Apr 14, 2015||Edwards Lifesciences Corporation||Unitary quick-connect prosthetic heart valve deployment system|
|US9005278||Oct 25, 2012||Apr 14, 2015||Edwards Lifesciences Corporation||Quick-connect prosthetic heart valve|
|US9011521||Dec 13, 2011||Apr 21, 2015||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US9060856||Feb 11, 2014||Jun 23, 2015||Medtronic Corevalve Llc||Transcatheter heart valves|
|US9060857||Jun 19, 2012||Jun 23, 2015||Medtronic Corevalve Llc||Heart valve prosthesis and methods of manufacture and use|
|US9066799||Jan 20, 2011||Jun 30, 2015||Medtronic Corevalve Llc||Prosthetic valve for transluminal delivery|
|US9078747||Nov 13, 2012||Jul 14, 2015||Edwards Lifesciences Corporation||Anchoring device for replacing or repairing a heart valve|
|US9078781||Jan 11, 2006||Jul 14, 2015||Medtronic, Inc.||Sterile cover for compressible stents used in percutaneous device delivery systems|
|US9089422||Jan 23, 2009||Jul 28, 2015||Medtronic, Inc.||Markers for prosthetic heart valves|
|US9125741||Mar 12, 2013||Sep 8, 2015||Edwards Lifesciences Corporation||Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves|
|US9131926||Nov 5, 2012||Sep 15, 2015||Boston Scientific Scimed, Inc.||Direct connect flush system|
|US9138312||Jun 6, 2014||Sep 22, 2015||Medtronic Ventor Technologies Ltd.||Valve prostheses|
|US9138314||Feb 10, 2014||Sep 22, 2015||Sorin Group Italia S.R.L.||Prosthetic vascular conduit and assembly method|
|US9149357||Dec 23, 2013||Oct 6, 2015||Medtronic CV Luxembourg S.a.r.l.||Heart valve assemblies|
|US9149358||Jan 23, 2009||Oct 6, 2015||Medtronic, Inc.||Delivery systems for prosthetic heart valves|
|US9155617||Apr 18, 2014||Oct 13, 2015||Edwards Lifesciences Corporation||Prosthetic mitral valve|
|US9161836||Feb 10, 2012||Oct 20, 2015||Sorin Group Italia S.R.L.||Sutureless anchoring device for cardiac valve prostheses|
|US9226826||Feb 24, 2010||Jan 5, 2016||Medtronic, Inc.||Transcatheter valve structure and methods for valve delivery|
|US9237886||Apr 14, 2008||Jan 19, 2016||Medtronic, Inc.||Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof|
|US9248016||Mar 3, 2010||Feb 2, 2016||Edwards Lifesciences Corporation||Prosthetic heart valve system|
|US9248017||May 20, 2011||Feb 2, 2016||Sorin Group Italia S.R.L.||Support device for valve prostheses and corresponding kit|
|US9277991||Dec 31, 2013||Mar 8, 2016||Boston Scientific Scimed, Inc.||Low profile heart valve and delivery system|
|US9277993||Dec 14, 2012||Mar 8, 2016||Boston Scientific Scimed, Inc.||Medical device delivery systems|
|US9289289||Feb 10, 2012||Mar 22, 2016||Sorin Group Italia S.R.L.||Sutureless anchoring device for cardiac valve prostheses|
|US9308085||Sep 23, 2014||Apr 12, 2016||Boston Scientific Scimed, Inc.||Repositionable heart valve and method|
|US9314334||Nov 25, 2013||Apr 19, 2016||Edwards Lifesciences Corporation||Conformal expansion of prosthetic devices to anatomical shapes|
|US9320599||Sep 24, 2014||Apr 26, 2016||Boston Scientific Scimed, Inc.||Methods and apparatus for endovascularly replacing a heart valve|
|US20020058995 *||Oct 23, 2001||May 16, 2002||Stevens John H.||Endovascular aortic valve replacement|
|US20030065386 *||Sep 28, 2001||Apr 3, 2003||Weadock Kevin Shaun||Radially expandable endoprosthesis device with two-stage deployment|
|US20030167089 *||Dec 26, 2002||Sep 4, 2003||Ernest Lane||Bioprosthetic heart valve|
|US20040122514 *||Jan 31, 2003||Jun 24, 2004||Fogarty Thomas J.||Biologically implantable prosthesis and methods of using the same|
|US20040176839 *||Mar 17, 2004||Sep 9, 2004||Huynh Van Le||Low-profile heart valve sewing ring and method of use|
|US20040225355 *||Jun 16, 2004||Nov 11, 2004||Stevens John H.||Endovascular aortic valve replacement|
|US20050137689 *||Dec 23, 2003||Jun 23, 2005||Sadra Medical, A Delware Corporation||Retrievable heart valve anchor and method|
|US20050197695 *||Feb 25, 2005||Sep 8, 2005||Sorin Biomedica Cardio S.R.L.||Minimally-invasive cardiac-valve prosthesis|
|US20060135964 *||Dec 28, 2005||Jun 22, 2006||The Cleveland Clinic Foundation||Bioprosthetic cardiovascular valve system|
|US20060136052 *||Dec 8, 2005||Jun 22, 2006||Valvexchange Inc.||Cardiovascular valve assembly|
|US20060195184 *||Feb 28, 2005||Aug 31, 2006||Ernest Lane||Conformable prosthesis for implanting two-piece heart valves and methods for using them|
|US20060195185 *||Feb 28, 2005||Aug 31, 2006||Ernest Lane||Two piece heart valves including multiple lobe valves and methods for implanting them|
|US20060195186 *||Feb 28, 2005||Aug 31, 2006||Drews Michael J||Connectors for two piece heart valves and methods for implanting such heart valves|
|US20060235508 *||Apr 10, 2006||Oct 19, 2006||Ernest Lane||Two-Piece Prosthetic Valves with Snap-In Connection and Methods for Use|
|US20070016288 *||Jul 13, 2006||Jan 18, 2007||Gurskis Donnell W||Two-piece percutaneous prosthetic heart valves and methods for making and using them|
|US20070150053 *||Dec 7, 2006||Jun 28, 2007||Gurskis Donnell W||Connection Systems for Two Piece Prosthetic Heart Valve Assemblies and Methods for Using Them|
|US20070162107||Mar 9, 2007||Jul 12, 2007||Sadra Medical, Inc.||Methods and apparatus for endovascularly replacing a patient's heart valve|
|US20070244558 *||Apr 4, 2007||Oct 18, 2007||Machiraju Venkat R||System and method for heart valve replacement|
|US20070276479 *||Jan 21, 2005||Nov 29, 2007||Roger Gregory J||Heart Valve|
|US20080004696 *||Jun 11, 2007||Jan 3, 2008||Valvexchange Inc.||Cardiovascular valve assembly with resizable docking station|
|US20080133003 *||Feb 11, 2008||Jun 5, 2008||Jacques Seguin||Prosthetic valve for transluminal delivery|
|US20080188929 *||Apr 8, 2008||Aug 7, 2008||Stefan Schreck||Methods of implanting two-part heart valves|
|US20090287296 *||May 13, 2009||Nov 19, 2009||Sorin Biomedica Cardio S.R.L.||Atraumatic prosthetic heart valve prosthesis|
|US20100161036 *||Dec 10, 2009||Jun 24, 2010||Edwards Lifesciences Corporation||Quick-connect prosthetic heart valve and methods|
|US20100191327 *||Apr 5, 2010||Jul 29, 2010||Medtronic, Inc.||Conformable prostheses for implanting two-piece heart valves and methods for using them|
|US20100274351 *||Apr 27, 2009||Oct 28, 2010||Sorin Biomedica Cardio S.R.I.||Prosthetic vascular conduit|
|US20100331972 *||Jun 23, 2010||Dec 30, 2010||Edwards Lifesciences Corporation||Unitary Quick Connect Prosthetic Heart Valve and Deployment System and Methods|
|US20120053688 *||Sep 22, 2011||Mar 1, 2012||Medtronic, Inc.||Biologically Implantable Prosthesis and Methods of Using the Same|
|USRE40377||Jun 7, 2004||Jun 10, 2008||Cardiovascular Technologies Llc||Means and method of replacing a heart valve in a minimally invasive manner|
|USRE44075 *||Jun 5, 2008||Mar 12, 2013||Medtronic, Inc.||Means and method of replacing a heart valve in a minimally invasive manner|
|EP1659981A2 *||Aug 19, 2004||May 31, 2006||Arbor Surgical Technologies, Inc.||Prosthesis fixturing device and methods of using the same|
|WO2003034950A1 *||Sep 26, 2001||May 1, 2003||Edwards Lifesciences Corporation||Low-profile heart valve sewing ring|
|WO2005020842A2 *||Aug 19, 2004||Mar 10, 2005||Arbor Surgical Technologies, Inc.||Prosthesis fixturing devices|
|WO2005020842A3 *||Aug 19, 2004||May 11, 2006||Arbor Surgical Technologies||Prosthesis fixturing devices|
|U.S. Classification||623/2.34, 623/2.38, 137/512.2, 137/513, 137/799|
|Cooperative Classification||A61F2/2409, A61F2/2421|
|European Classification||A61F2/24F, A61F2/24C|