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Publication numberUS3856185 A
Publication typeGrant
Publication dateDec 24, 1974
Filing dateDec 26, 1973
Priority dateDec 26, 1973
Also published asCA1010425A1, DE2461376A1, DE2461376B2, DE2461376C3
Publication numberUS 3856185 A, US 3856185A, US-A-3856185, US3856185 A, US3856185A
InventorsRiccio P
Original AssigneeCiba Geigy Corp
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Single dose, replaceable supply air pressure operated dispenser
US 3856185 A
Abstract
A single dose dispensing device for aspirating a product located in a replaceable container by means of compressed air is disclosed. The device includes a piston-cylinder assembly having a movable member and a fixed member and has a compressed air flow path therethrough with an aperture at the free end of the fixed member. A product dispensing member, also having a compressed air flow path therethrough is connected to the piston-cylinder assembly, the respective compressed air flow paths being in communication with one another. The dispensing member further includes a product storing chamber and an aspirating means in communication with both the product storing chamber and the compressed air flow path. A diaphragm member normally blocks the compressed air flow path and is adapted to open when the movable member substantially completes a compression stroke, thus allowing product to be dispensed by means of compressed air.
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Description  (OCR text may contain errors)

United States Patent 1 Riccio [45 Dec. 24, 1974 SINGLE DOSE, REPLACEABLE SUPPLY- AIR PRESSURE OPERATED DISPENSER Inventor:

[73] Assignee:

Filed:

Appl. No.:

Dec. 26, 1973 Pasquale R. Riccio, Salem, N.H.

Ciba-Geigy Corporation, Ardsley, N.Y.

US. Cl 222/193, 128/266, 239/309 Int. Cl B67d 5/54 Field of Search 222/83, 193, 145, 391;

References Cited UNITED STATES PATENTS 8/1950 Fields 4/1966 11/1970 Oakes Corsette et a1.

Wells 222/193 X 128/266 222/385 X Solowey 222/83 FOREIGN PATENTS OR APPLICATIONS l l l n Great Britain 128/265 Primary Examiner-Stanley 1-1. Tollberg Assistant Examiner-Norman L. Stack, Jr. Att0rney,'Agent, or Firm-Wenderoth, Lind & Ponack [57] ABSTRACT A single dose dispensing device for aspirating a product located in a replaceable container by means of compressed air is disclosed. The device includes a piston-cylinder assemblyhaving a movable member and a fixed member and has a compressed air flow path therethrough with an aperture at the free end of the fixed member. A product dispensing member, also having a compressed air flow path therethrough is connected to the piston-cylinder assembly, the respective compressed airflow paths being in communication with one another. The dispensing member further includes a product storing chamber and anaspirating means in communication with both the product storing chamber and the compressed air flow path. A diaphragm member normally blocks the compressed air flow path and is adapted to open when the movable member substantially completes a compression stroke,

thus allowing product to be dispensed by means of compressed air.

10 Claims, 2 Drawing Figures BACKGROUND OF THE DEVICE 1. Field of the Invention The invention relates to a dispenser and particularly to a device for dispensing a single dose of material preferably powder, by means of aspiration using compressed air, and in which the supply of dispensed material is readily replaceable.

2. Description of the Prior Art The art of dispensing material is highly developed. Recently there have been great advances in the art of dispensing materials by means of a compressed propellant while keeping the material and propellant separate prior to dispensing. This is typified by the recently developed so-called double aerosol type dispensers which are quite satisfactory, but nevertheless have some disadvantages, particularly where they must be made in small sizes.

A most serious disadvantage arises from the fact that so-called aerosol propellants are used to dispense the material. When medicaments are dispensed from the inhaler type devices, these propellants are inhaled by.

the user along with the medicament. It has recently been reported that fluorocarbon propellants, e.g. Freon which is a commonly used propellant, may be highly toxic, and the same situation may be found to hold true for other propellants. Pharmaceutical marketers would thus prefer to have the product dispensed by air instead of the chemical vapor conventionally used as a propellant.

A further disadvantage of the prior art dispensing devices is leakage of propellant from the propellant car tridge during storage, which reduces the shelf life of the dispenser. Additionally, the problem of exactly matching the amount of propellant with the amount of material to be dispensed is often difficult because of leakage problem. Also because of differences between the various materials being dispensed a proper amount of propellant for the material will not suffice or will be in excess of that necessary for dispensing all of another material. In the first instance, part of the product is wasted and in the second instance part of the propellant is wasted.

A further disadvantage is that, with compressed gas type propellants when the propellant is running low, the dispensing of the last of the material to be dispensed can be carried out only at a very slow rate, as compared to when the dispenser is initially filled with propellant, when dispensing takes place rapidly.

Many of these disadvantages could be overcome if, instead of using compressed conventional propellant gases, air was used as a propellant and was compressed each time the dispensing operation was to be. carried out. Conventional squeeze bulb and piston-cylinder atomizers operate somewhat in this fashion bu have the serious drawback that the compression is carried out gradually, the amount of material dispensed being dependent on how fast and with what force the squeeze bulb or'the piston-cylinder means is operated. They very often include a check valve at the delivery end of the cylinder, but this valve does not provide any significant resistance to flow of compressed gas once the piston starts to move into the cylinder. v

A number of devices have recently been invented which use charges of compressed air which are produced at each actuation of the device. However, these devices tend to be somewhat complex and hence rather expensive to make.

Technical progress would be achieved if there could be provided a simply constructed device which would dispense single doses of product with air compressed as the device is actuated under the control of a very simple and easily made means, the parts of which device would be simple to mold in plastic, and which could have the product supply readily replaced.

OBJECTS AND SUMMARY OF THE INVENTION It is an object of the present invention to provide a simple and compact single dose dispensing device having a replaceable supply cartridge, which utilizes compressed air for aspiration in a manner so as to overcome. all of the recited disadvantages of the prior art dispensers.

It is further object of the present invention to provide a simple and compact single dose dispensing device having a replaceable supply cartridge which utilizes compressed air that is compressed as the dispensing takes place, but which releases the compressed air only after the pressure has built to a desired level.

It is a still further object of the present invention to provide a simple and compact dispensing device which can be stored without loss of a propellant and without a product container, therefore having an unlimited shelf life, which can also be stored without fear of an explosion of a compressed propellant and which can be shipped in interstate commerce as a non-pressurized item, thereby eliminating the need for special packaging and labeling.

It is a still further object of the invention to provide a simple and compact single dose dispensing device having a replaceable supply cartridge, preferably for a powdered medicament, which has a positively operated simple diaphragm member in a compressed airflow path between a piston and aspirating means. The diaphragm member seals the compressed air flow path when product is not being dispensed.

These objects are achieved by providing a dispensing device having a piston-cylinder assembly defining a compressed air flow path therethrough and having a piston slidable therein. A single dose, replaceable product dispensing member having aspirating means is removably connected to the piston-cylinder assmbly such that the aspirating means communicates with the compressed air flow path therein. The product dispensing member has adiaphragm member operatively positioned across the compressed air flow path.'The pistoncylinder assembly preferably has a cylinder around the compressed air flow path and has a piston slidable therein. A piston rod is connected to the piston for moving the piston into the cylinder. When the piston 1 reaches substantially the inner end of the cylinder, the

diaphragm member and consequently the compressed air flow path opens, thus releasingthe compressed air 'from the cylinder. The actuation of the aspirating means in response to the compressed air causes the product to be dispensed. The dispensing member is then replaced by a full one. All of the parts of the device are easily molded in plastic and easily assembled.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a side view of the device constructed in accordance with a subject disclosure;

FIG. 2 is a sectional elevation view of the device of 5 FIG. 1 with the parts in the rest or non-dispensing position.

DETAILED DESCRIPTION OF THE INVENTION Referring first to FIG. 1, a side view of a configuration of the subject invention is disclosed. A single dose, replaceable product dispensing member is inserted within and retained by a dispenser l2 and operatively communicates therewith. The dispenser 12 has a piston which is operated by means of piston rod 18 to produce a compressed air supply which is fed to the product dispensing member 10 for aspiration ofthe material, preferably powder, contained in the member.

Next, referring to FIG. 2, which discloses a cross sectional elevation view of the device of FIG. 1, the compressed air is generated by an air compressing pistoncylinder means which may be a hollow cylinder 14 having an aperture at one end and an aperture in the lateral surface of the cylinder at the opposite end thereof. A piston member 16 is slidably positioned within the cylinder l4 and the piston rod 18 is an extension thereof which extends through the end aperture of the cylinder 14. The piston member 16 has a piston face 20, the piston being slidably retained within the cylinder by means of retaining cap 22. The cylinder further includes a partition member 24 having an aperture 26 therein. A probe member 28 protrudes from the face of the piston in alignment with the aperture 26.

Compression ring 30 seals the piston head in its movement within the cylinder 14 and a return spring 32 within the cylinder normally urges the piston away from the partition member 24. The piston, the partition and the cylinder define a chamber 34 for compressing air.

Product dispensing member 10 is a sepa'rate replaceable body which is insertable through the first lateral aperture in the cylinder as shown. The dispensing end of the member 10 has an outer annular channel 36 and an inner recessed region 38 having a central passageway 39 extending from the recessed region 38 and intersecting a lateral opening 40 of a larger diameter which opens laterally out of the member 10. A Venturi nozzle insert 42 is seated in the inner recessed region 38 and an aperture cover 44 sits within the annular channel 36 and fits over the Venturi nozzle insert 42; an elongated extension 46 fitting tightly against the peripheral wall 48 of the dispensing member 10. A tab seal 50 is provided over an aperture in the cover and the Venturi nozzle and is removed prior to operation of the device.'This tab seal insures that the product will not become contaminated and also prevents the unintentional egress of product from the device.

The Venturi nozzle 42, cover 44 and member 10 define a supply chamber 45 from which passages 47 open into the central passage of nozzle 42. Supply chamber 45 can be filled by loading a preferably powdered product through material supply passageway 52 which communicates with the supply chamber. A thumb knockout pin 54 may optionally be provided on the dispensing member. The cylinder 14 has a second lateral aperture 56 through which extends the thumb knockout pin 54. An air tight seal 58 is provided over the back of member 10 to prevent leakage of compressed air, to seal the supply passageway 52, to protect the .product contained in the supply chamber from contamination and to retain the product therein.

The air flow path-which begins at the passageway 39 is normally blocked by solid, breakable diaphragm member 60 which is preferably seated in a recessed region of the dispensing member 10 in coaxial relationship with lateral opening 40. The diaphragm member may be constructed of paper, plastic or the like and fits snugly within the recess to block the compressed air flow path. The diaphragm member initially acts, in combination with the partition member 24, as an end of a compression chamber; the other end being formed member is broken, compressed air surges through passageway 39 and into the Venturi nozzle 42 and the material in supply chamber 45 is aspirated therefrom and dispensed through theVenturi nozzle 42.

Operation of the device is as follows:

When pressure is exerted by the fingers of the user on the piston rod 18, air is compressed in the cylinder 14 ahead of the piston face 20. The diaphragm member 60 blocks the passage of air until the piston reaches the end of its stroke, at which time the diaphragm member opens and the compressed air in the cylinder is suddenly released to flow through the compressed air flow path and the product dispensing member, causing aspiration of the product as described above.

The memberlO contains a single dose of product and may be removed, for instanceby pressing the thumb knockout pin 54, from the dispenser and a new capsule may be coupled thereto in preparation'for the next dispensing operation. The piston 16, upon release, returns to its initial position due to the force exerted by the spring 32. v

It will be seen that a simple diaphragm is provided in the replaceable member 10. instead of there being a more complex valve and spring arrangement. All of the parts are easily molded of plastic, except for return spring 32, so that the device is easily and inexpensively manufactured. v

It is thought that the invention and its advantages will be understood from the foregoing description, and it is apparent that various changes may be made in the form, construction and arrangement of the parts without departing from the spirit and scope of the invention or sacrificing its material advantages, the form hereinbefore described and illustrated in the drawings being merely a preferred embodiment thereof.

I claim:

1. A single dose replaceable product supply dispensing device comprising: I v a piston-cylinder means having a movable member and a fixed member having a compressed air flow path therethrough with an aperture at thelend remote from said movable member;

a single dose replaceable product dispensing member having a product dispensing aperture and adapted to be operatively connected to said fixed member and having a compressed air fiow path therethrough, said fiow path being operatively positioned relative to said compressed air flow path of said piston-cylinder means when said product dispensing member is connected to said fixed member for communication therebetween, said dispensing member further having a product supply chamber, and aspirating means in said compressed air flow path communicating with said product supply chamber for dispensing said product via said product dispensing aperture; and

a diaphragm member normally blocking the compressed air flow path and adapted to open only when said movable member approaches thereto, during its compression stroke;

whereby as said movable member moves toward said fixed member in a compression stroke, air is compressed in the fixed member, said diaphragm member remaining closed until said movable member substantially reaches the end of its compression stroke whereupon said diaphragm member opens, allowing compressed air to travel along said compressed air flow path into said product dispensing member and through said aspirating means, product being dispensed thereby.

2. In the dispensing device of claim 1, said diaphragm member being a solid breakable member and said de- 4. In the dispensing device of claim 3, said cylinder further having an aperture in the lateral surface thereof and. said product dispensing member being insertable therethrough whereby said product dispensing member is operatively seated within said cylinder.

5. The device of claim 4, wherein said aspirating means is a Venturi nozzle insert member in said compressed air flow path and having lateral passages extending to said product containing chamber, said product being aspirated by said compressed air flow through said nozzle and being dispensed through said nozzle.

6. The device of claim 5, wherein said product dispensing member further comprises a thumb knockout pin extending from an end of said product dispensing member opposite said product dispensing aperture and said cylinder further having a second lateral aperture opposite said first lateral aperture, said pin extending through said second lateral aperture.

7. The device of claim 6, wherein said product dispensing member further comprises an annular cartridge member having a substantially cylindrical shape,

and having opposite ends, one end thereof having an outer annular channel and an inner recessed portion, said compressed air flow path extending from said recessed portion to the lateral surface of said annular cartridge member, said Venturi nozzle insert being seated within said inner recessed portion, a cartridge cover having a central aperture and having an elongated portion positioned within said outer annular channel, said central passage being positioned in alignment with said Venturi nozzle and said cartridge cover, said Venturi nozzle insert and said cartridge member end forming said product supply chamber.

8. The device of claim 7, wherein said cartridge member further has a material filling passageway communicating with said product supply chamber and the opposite end of said cartridge member.

9. The device of claim 8, further comprising a first removable sealing member positioned over said Ven-' turi'nozzle for preventing contamination of the product contained therein and a second sealing member positioned over the opposite end of said member.

10. A single dose replaceable product dispensing member for dispensing a product by means of compressed air supplied by a dispensing device, comprising:

a dispensing member body, one end thereof having an outer annular channel and an inner recessed portion, a first aperture within said inner recessed portion, a second aperture through which compressed air may be admitted to said dispensing member, a compressed air flow path between said first andsecond apertures, aspirating means comprised of a Venturi nozzle insert member having a central air passageway positioned within said inner recessed portion in operative alignment with said first aperture and receiving compressed air therefrom, said Venturi nozzle insert member further having lateral passageways extending from the central air passageway to the periphery of a cover member having a central aperture positioned over said one end of said dispensing member said central aperture being in alignment with said Venturi nozzle insert member, said cover member, said Venturi nozzle insert member and said dispensing member body defining a product supply chamber, said product supply chamber communicating with the central passageway of said nozzle insert member through said lateral passageways, and a material filling passageway intersecting said product supply chamber in said outer annular channel and intersecting an opposite end of said dispensing member whereby product may be supplied to said chamber and a diaphragm member normally blocking said compressed air-flow path and adpated to open when the pressure of said compressed air supplied to said dispensing member exceeds a predetermined value whereby compressed air aspirates product as the compressed air passes through said Venturi nozzle member insert, product being thereby dispensed.

Patent Citations
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Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US5027808 *Oct 31, 1990Jul 2, 1991Tenax CorporationBreath-activated inhalation device
US5178513 *Oct 8, 1991Jan 12, 1993Sundstrand CorporationTurbine nozzle phasing device
US5301664 *Mar 6, 1992Apr 12, 1994Sievers Robert EMethods and apparatus for drug delivery using supercritical solutions
US5307953 *Dec 2, 1992May 3, 1994Glaxo Group LimitedSingle dose dispenser having a piercing member
US5547131 *Jun 3, 1994Aug 20, 1996Bespak PlcDispensing device with spray nozzle and driven piston
US5639441 *Apr 8, 1994Jun 17, 1997Board Of Regents Of University Of ColoradoDissolving substance to form solution, mixing with fluid which forms gas on rapid depressurization, depressurization
US6095134 *Apr 24, 1997Aug 1, 2000The Board Of Regents Of The University Of CoMethods and apparatus for fine particle formation
US8734392May 18, 2004May 27, 2014Aptar Radolfzell GmbhDosing device having a pumping device
US8800550Nov 26, 2008Aug 12, 2014Innovata Biomed LimitedMedicament delivery assembly
US20130289595 *Apr 26, 2012Oct 31, 2013Gyrus Ent, L.L.C.Surgical instrument
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EP1446181A2 *Nov 22, 2002Aug 18, 2004Innovata Biomed LimitedMedicament delivery assembly
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WO2011013003A2Aug 2, 2010Feb 3, 2011Shin Nippon Biomedical Laboratories, Ltd.Intranasal granisetron and nasal applicator
WO2013033321A1 *Aug 30, 2012Mar 7, 2013Mccormick & Company, IncorporatedParticulate sprayer
WO2013150129A1 *Apr 5, 2013Oct 10, 2013Rpc Formatec GmbhDispenser for discharging an in particular granular or powdery substance, and method for emptying a substance reservoir
Classifications
U.S. Classification222/635, 604/58, 604/143, 239/309
International ClassificationA61M15/00, A61M11/06, B05B11/06
Cooperative ClassificationA61M11/06, A61M15/0028, A61M2205/073, A61M2202/064, B05B11/062
European ClassificationA61M15/00C, B05B11/06B, A61M11/06