Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS3912933 A
Publication typeGrant
Publication dateOct 14, 1975
Filing dateOct 17, 1973
Priority dateOct 17, 1973
Also published asDE2449149A1, DE2449149B2, DE2449149C3
Publication numberUS 3912933 A, US 3912933A, US-A-3912933, US3912933 A, US3912933A
InventorsStappen Albert L Van
Original AssigneeDu Pont
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Fine detail radiographic elements and exposure method
US 3912933 A
Images(6)
Previous page
Next page
Description  (OCR text may contain errors)

United States Patent Van Stappen [451 Oct. 14, 1975 FINE DETAIL RADIOGRAPHIC ELEMENTS AND EXPOSURE METHOD [75] Inventor: Albert L. Van 'Stappen, Rumson,

[73] Assignee: E. I. Du Pont de Nemours and Company, Wilmington, Del.

22 Filed: Oct. 17,1973

21 App]. No.: 407,165

[52] US. Cl. 250/475; 96/82; 250/482 [51] Int. Cl. G03b 41/16 [58] Field of Search 250/475, 480, 482; 96/82 [56] References Cited UNITED STATES PATENTS l 1968 Haefner 250/482 11/1968 Sherwood 250/480 1 l/l97l Staudenmayer 96/82 8/1973 Sugiyama 96/82 Primary ExaminerJames W. Lawrence Assistant Examiner-C. E. Church [57] ABSTRACT A novel film/screen combination particularly useful for the radiographic examination of the breast (e.g. mammography), body-section radiography (e.g. tomography), industrial radiography, and for radiographic examination of the extremities is disclosed' 8 Clains, No Drawings FINE DETAIL RADIOGRAPHIC ELEMENTS AND EXPOSURE METHOD BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a novel combination of X-ray film and X-ray intensifying screen suitable for use in X-ray examinations such as those used in mammography, tomography, for extremities and industrial evaluations.

2. Description of the Prior Art Radiographic examination procedures are now widely used for diagnosis of medical abnormalities and to detect tumors. Where the definition of the abnormality is high compared to the surrounding tissue, high speed medical X-ray film can be used in conjunction with a fluorescent X-ray intensifying screen to detect the abnormality with the lowest amount of patient exposure to X-rays. In the fleshy parts of the body, where the definition of the abnormality is lower, the use of screens in conjunction with an increase in X-ray dosage is not usually successful in locating the abnormality due to side effects caused by the intensifying screen such as quantum mottle or screen noise. These effects are discussed by Sturm et al. in The Am. Journal of Roent. and Rad. Therapy, Vol. 62, No. 5 pp. 6l7634, Nov. 1949 and by Cleare et al in Radiology, Vol. 88, No. 1, pp. 168-174, July 1962. These effects are particularly noticeable when trying to detect tumors and cancerous growths by X-ray examinationof the adult female 3 breast. This procedure is known'as mammography. In order to properly diagnose suspected growths, it is customary to use relatively thick industrial-type X-ray film without a screen and to increase the X-ray output in order to cause exposure on the film. This technique has been well taught by Leborgne in The Am. J. of Roent. and Rad. Therapy, Vol. 65, No. 1, pp. l 1l, January 1951 and by Egan in Radiology, Vol. 75, pp. 894-906, Dec. 1960. Exposure times up to 6 seconds at 300Ma, 22-28kVp at a distance of about 40 inches are re quired as reported therein. With six exposures, the total dosage is over 10,000 Mas as compared with about 2 Mas for a normal chest X-ray. In addition, the patient may move during the long exposure time destroying the results and requiring the procedure to be repeated, thus doubling an already dangerously high dosage. Even under the best conditions, involuntary movement of the patient due to heart beats, etc. during the long exposure time causes unsharpness of the image and valuable radiographic information may be lost. Additionally, the industrial-type, thick X-ray film presently used for mammography cannot be processed in the machines at the same time and temperature as is normally used for medical X-ray (i.e., fast access, 90 seconds processing time). Changing machine conditions is tedious and cannot be reproducibly done from time to time. Thus, they are sometimes processed in tanks or trays. The modern hospital may not be fully equipped with a photographic dark room and much additional valuable time may be lost. Some industrial X-ray films are now designed for fast access machine processing but still present the disadvantages of exposure times and patient dosage mentioned above.

Another procedure now used in X-ray diagnostic work is known as tomography or body-section radiography. This technique is well described by Selman in The Fundamentals of X-ray and Radium Physics,

Charles C. Thomas, Publisher, 1967, pp. 344351. Some areas of the human body are difficult to radiograph without confusing shadows of superimposed structures. The body-section radiographic technique uses a moving radiographic X-ray source and a photographic film moving in the opposite direction. Several films are exposed in this manner, and at one point, the desired structure will appear the sharpest. Photographic films used for this radiographic analysis are usually of-the high speed type, and the emulsion is coated on both sides of the support. Thus, the resulting silver images are separated in distance by the thickness of the support layer. When the incident x-radiation used to expose the image is perpendicular to the film, both image areas will be directly superimposed and the image will be sharp. In body-section radiography, however, the incident light is sometimes not perpendicular to the film surface, and the image on one side of the film support will be slightly out of line from that on the other side resulting in an un-sharp picture.

Yet another application for X-ray films is in the industrial field. Here, metal parts such as aircraft wings, steel girders for bridges, etc. are evaluated for internal flaws and stress points by exposing the desired area using standard, thick, double-coated industrial X-ray film. Since metal has a higher resistance to the penetration of the x-radiation, higher energy or X-ray output is needed. Standard industrial X-ray film is normally used without screens, since the films are coated with a relatively thick layer of sensitive silver halide, and the use of screens would produce poor image sharpness which would severely interfere with this particular analysis. These films, of course, cannot be processed in the machines under so-called fast access conditions (ie seconds processing time) and thus rapid evaluation of results is not possible.

It has been found according to thepresent invention that radiation exposure canbe dramatically reduced without sacrificing image contrast, using an optimal combination of a fine grain silver halide emulsion and intensifying screen. Additional advantages include reduction in motion unsharpness, rapid film processability and conservation of silver.

SUMMARY OF THE INVENTION The invention relates to a radiographic element comprising a film support with a single silver halide emulsion layer and an antihalation layer, said silver halide emulsion having an average silver halide grain size of 0.4 to 1.2 microns, and an X-ray intensifying screen in contact therewith, said emulsion layer and screen having a speed factor between 2.5 and 4.5. The invention also includes the process of exposing said radiographic element to X-radiation.

DESCRIPTION OF THE PREFERRED EMBODIMENTS The X-ray screen is preferably held in intimate contact with the silver halide X-ray film by an evacuated vacuum cassette with flexible sides, e.g., a plastic bag, as is well known in the art. The film-screen combination has characteristics particularly designed, so that the ultimate in photographic speed is balanced with the diagnostic information obtainable at the lowest possible X -ray dosage. This combination yields a product completely compatible with current X-ray laboratory processing systems and yet able to match all current diagnostic information at much lower X-ray dosage than that employed with industrial X-ray film when used, for example, in mammography.

The photographic film useful herein is comprised of a support having a single photographic gelatino silver halide emulsion coated thereon having the average silver halide grain size between 0.4 to 1.2 microns. Preferably, this emulsion is comprised mainly of silver bromide grains with small amounts (about 1 to 4 mole percent) of silver iodide. The emulsion is preferably sensitive mainly to blue light so as to be particularly useful when used with an X-ray intensifying or fluorescent screen. The contrast in the toe portion of the H&D curve of the emulsion will be at least 2.5 in the region of D 0.2 to 2.0. The emulsion is preferably prepared with a controlled amount of binder, so that the resulting product, when coated on a suitable support (i.e., polyethylene terephthalate) is processable in rapid access machines as taught, for example, by Barnes in U.S. Pat. No. 3,545,971. Preferably, the film support will also contain a blue dye incorporated therein as taught, for example, by Johnes et al in British patent appln. Ser. No. 1,196,707, /28/70. A gelatino layer containing an antihalation dye dischargeable in the processing fluids, is preferably coated on the films support opposite tothat side bearing the silver halide emulsion layer. It may, however, be on the same side as the emulsion layer. Such antihalation layers are used to prevent reflected light and are well known in the art. A gelatin protective top coat is applied as a contigous layer to the silver halide bearing stratum.

The"X-ray intensifying screen used in conjunction with the photographic film described above is preferably prepared by dispersing a suitable phosphor (e.g. calcium tungstate) in a binder such as chlorosulfonated polyethylene, n-butyl acetate, or cellulose acetate, etc., using a solvent such as ethyl alcohol. Other adjuvants such as wetting agents, etc., may also be incorporated therein and the resulting dispersed phosphor may be coated over a suitable reflective layer (e.g. TiO which has been applied to a suitable sheet support as well known to those skilled in the art. A protective top coat, e.g. cellulose acetate, may also be applied thereon so as to provide suitable protective qualities to the finished screen and prevent subsequent damage during handling. The reflective underlayers used in screens of this invention may also contain optical brighteners such as the aminocoumarins of Patten as taught in British Pat. No. 999,780, July 28, 1965. Filter dyes which screen out unwanted radiation as known to the skilled artisan may also be used in the phosphor layer or in the protective top coat coated thereon. In place of the calcium tungstate described above there may be substi tuted known phosphors such as zinc sulfide, zinc oxide and calcium silicate, zinc phosphate, alkali metal halides, cadmium sulfide, cadmium selenide, zinc selenide, zinc telluride, cadmium telluride, cadmium tungstate, magnesium fluoride, zinc fluoride, strontium sulfide, zinc sulfide, barium lead sulfate, cadmium barium fluoride, gadalonium oxysulfide, lanthanium oxysulfide and mixtures thereof. Phosphors whose efficiency has been increased by the addition of doping agents, e.g. europium and terbium may also be used. The term phosphors", as used herein, denotes any suitable material that will luminesce upon exposure to X-rays, such as those set forth above.

The screens used with the single emulsion layer photographic films of this invention should possess a certain speed factor. This factor is determined by exposing the film to an X-ray source with and without a screen through a step wedge, developing the exposed film and plotting the resulting sensitometric curves. From these curves, the exposure required to obtain a film density of 1.00 is determined, and the speed factor of the xray screen is determined from the following formula:

gm E2 gIO I Speed Factor (SF) 30] where E exposure required to give unit film density with screen E exposure required to give unit film density without screen Within the ambit of this invention and the above definition, the screen-film combinations of this invention should have a Speed Factor of between 2.5 and 4.5 and, most preferably, between 3.0 and 4.2, where E is in milliampere seconds (Mas) at a given distance (e.g. 40 inches) and kilovolts p'eak (e.g. 40 kVp), using, e.g. a 1 /2 mm aluminum filter. If, the speed factor is too high, the granularity of the resulting film used therewith will appear too high, and the fine detail needed in any radiographic examination would be strongly reduced. 1f the speed factor is too low, increased exposure is necessary which is dangerous to the patients health as described previously.

Yet another method of expressing the screen speed is to define the energy necessary, in terms of x-ray output, to produce a desired degree of blackening of the photographic film used therewith. For example, with the screens of this invention, used with the films of this invention, and with the x-ray generator set at 40 kilovolts peak (kVp) and 2 milliamperes tube current, one places the film-screen combination at a distance of 40 inches. Exposures are made at these conditions varying the time, and the density of the developed film therefrom is measured. To produce a density of 1.0 on the films of this invention with the above screens requires about 420 milliampere seconds (Mas) using a single phase generator through a llmm aluminum filter. The most preferred film-screen combinations produce a density of 1.0 with about 6-10 Mas.

The quality of the image which can be produced by the screen/film combination described is such that calcifications in the female breast as small as 0.1 mm can be resolved by the system. One method for demonstrating the ability of a photographic system to resolve small objects is to measure the sine or square wave response, or as it is now called, the Modulation Transfer Function (MTF). The procedure for measuring this response is taught by Perrin in J. Soc. Motion Picture and Television Engrs., 69 151 (1960) and Perrin, ibid, 259 (1960) and its use in X-ray film/screen combinations is described by Coltman in J. Opt. Soc. Am., 44 468 (1954) and by Rossman in J. Opt. Soc. Am., 52, 774 (1962). The spatial frequency of a test pattern produced by the system is measured in cycles/mm and the results shown on an oscilloscope. Typical MTF values for the film/screen combination of this invention are shown below:

. Frequency MTF Value (71) (Cycles/mm) In order to produce a properly defined image within the scope of this invention, the film/screen .combination should have a MTF value no less than 90% of these values at any frequency. For example, at 2 cycles/mm frequency, the MTF value should be at least 67.5 (i.e., 90% of 75).

As described above, emulsions useful within the ambit of this invention preferably are composed mainly of silver bromide with small amounts of silver iodide. However, emulsions containing other halides (e.g. chloride or mixtures of bromide-chloride-iodide) may also be used if properly prepared and sensitized. These emulsions are usually brought to their optimum sensitivity as regards speed, fog and contrast, with, for example, gold and sulfur as taught in US. Pat. Nos. 1,574,944; 1,623,499; 2,410,699; 2,399,083; 2,448,060 and 2,597,915 as well as the reducing agents of U.S. Pat. No. 2,487,850. Other sensitizing agents and speed increasing adjuvants well-known to those skilled in the art may alsobe advantageously employed herein. After sensitization is complete, other adjuvants (e.g. wetting and coating aids, hardeners, antifoggant and stabilizers, etc.) may also be added. The emulsion may be coated on any suitable film support (i.e. poly-' ethylene terephthalate prepared and subbed as described in Alles U.S. Pat. No. 2,779,684, Example IV) by any of the means disclosed in the prior art (i.e. skim, air-knife, bar or falling film coating techniques). Other suitable supports include glass, cellulose acetate, cellulose nitrate and other synthetic film forming resins or polymers (e.g. polyester, polyamides, polystyrene, etc.). The film elements may also contain anti-curling backing layers and said backing layers may contain other adjuvants such as antistatic or slip agents, antihalation dyes, etc., in fact it is so preferred. The use of antihalation dyes within the backing layer of the preferred element enhances the image quality by preventing light reflection. The antihalation-layer may also be coated under the emulsion layer as known to those skilled in the art.

The emulsions of this invention may contain any of the well-known binding agents such as gelatin, albumin, agar-agar gum arabic, dextran, alginic acid, polyvinyl alcohol, polyvinyl pyrrolidone, cellulose ether, partially hydrolysed cellulose acetate, alkyl acrylate polymers, the modified and hydrolysed gelatin of Rakoczy, US. Pat. No. 3,778,278, or mixtures of two or more of those described above, may be used equally as well. One only needs to balance the sensitivity of the emulsion used and the inherent grain size with the speed range of the intensifying screen described previously to achieve the desired effect. This fact could not have been predicted from the prior art, since it was taught that the use of intensifying screens with photographic films increased the noise level so that fine details would be lost. Contrary to this teaching, it has now been found that the balance of emulsion and screen characteristics according to the invention will produce an element with good speed (i.e. lower patient dosage) and effectively record the necessary radiographic information. Additionally, by proper selection of binder and binder/silver halide ratio of the single emulsion layer one may achieve an element that may be processable in the automatic developing machines now widely used in the art. The use of a single layer also prevents exposure from two sides of the film from occurring. This is known as printthrough and results from an exposure with double coated film and two x-ray screens. Light emitted from one screen should expose the emulsion only on the side nearest the screen. In point of fact, some light returns through the base and exposes emulsion on the reverse side resulting in a blurred image. This is highly undesirable and cannot be tolerated expecially in the X-ray evaluations previously described. The novel system of the invention prevents print-through by providing only a single side coated emulsion and one screen. Since the speed of the system is high enough to use short exposure times, involuntary movement of the patient, which also results in image blurring, is not a problem. All of these advantages were a distinct need in the fields of mammography and of radiological evaluation of extremities.

This invention will now be illustrated by, but is not limited to, the following examples:

EXAMPLE 1 A silver halide emulsion comprised of about 98 mole percent silver bromide and about 2 mole percent silver iodide was prepared in the manner known to those skilled in the art. The silver halide mean grain size was kept at about 1.0 micron by carefully controlling the variables of rate of addition of the silver nitrate to the ammoniacal halide solution and the ripening time and temperature. During the preparation procedure, only a small amount of inert bone gelatin was present (about 20 g./l .5 moles of silver halide). The silver halide precipitate in this small amount of gelatin was then redispersed by vigorous stirring in water and gelatin (about g. gelatin/1.5 moles of silver halide) and the pH adjusted to 6.5 i 0.1. The emulsion was then brought to its optimum sensitivity by digestion at a temperature of about F with gold and sulfur sensitizers. The usual wetting agents, coating aids, antifoggers and emulsion hardeners were added thereto. All of these steps, adjuvants and methods of preparation are well-known to those skilled in the art of emulsion making and any number of sensitizers and other adjuvants can be used with equivalent results. The emulsion was coated on polyethylene terephthalate film base containing a blue dye which imparts a blue tint to the base as described in British patent application Ser. No. 1,196,707. The film base had been first coated on both sides with a vinylidene chloride-alkyl acrylate/itaconic acid copolymer mixed with an alkyl acrylate and/or methacrylic polymer as described by Rawlins in US. Pat. No. 3,433,950 over which had been coated on both sides a thin anchoring substratum of gelatin (0.5 mg/dm l).

The dried emulsion coated thereon had a coating. weight of about 95mg of silver halide/dm and wasovercoated with a thin protective layer of hardened gelatin of about l mg gel/dm Coated on .the opposite side of the film support'was a gelatin anticurling and antihalation layer containing about 60 mg gel/dm and antihalation dyes which absorb principally between about 370 nm and 550 nm and are dischargeable in the processing fluids used to develop andfix the photographic image later applied to the silver halide layer.

An X-ray intensifying screen was prepared by first coating a TiO reflective layer comprised of TiO dispersed in a chlorosulfonated polyethylene binder solution (16% chlorosulfonated polyethylene in, for example, n-butyl acetate/mixed petroleum naphtha solution) on 0.01 inch thick biaxially oriented polyethylene terephthalate sheet to avwet thickness of about 0.001 inch. A phosphor suspension comprising 6600 g. of CaWO, phosphor in a l3.3% polyvinyl butyrate binder solution (n-butyl acetate/n-propanol solvent) was ball-milled for about 16 hours and cast over the TiO layer at a wet thickness of about 0.013 inches, dried and overcoated with a protective layer of cellulose acetate dispersed in acetone to which had been added 8 mls. of a dye solution/1000 g. of the cellulose acetate solution. The dye solution comprised a yellow dye (C.l. Solvent Yellow No. 47) in alcohol, 25g. dye/805 ml. alcohol. The protective coat was applied to the dried phosphor layer at a wet coating thickness of about 0.0013 inches and subsequently also dried.

A sample of the film prepared above was placed in contact with the screen described, with the protective layer of said screen in contact with the emulsion layer of the film element, and this combination, which had a speed factor of 3.1, was placed in a vacuum cassette and evacuated to insure good film/screen contact. This cassette was then placed with the side containing the antihalation layer facing an X-ray source, and a phantom which simulates the female breast plus a hand (to test for extremities) phantom were placedlfthereon. The breast phantom included fine aluminum wires incorporated therein to simulate fine calcium deposits, which may be indicative of early carcinoma of the breast (i.e., during a mammographic examination for breast cancer), a cellulose capsule to simulate coarse, opaque lumps and a gelatin capsule to simulate coarse, transparent lumps. The hand phantom contained cubes of a calcium compound to simulate bone structure. This phantom is made by Minnesota Mining and Manufacturing Co. and is standard for such simulated evaluations. The X-ray source was 40 inches away from the film and was operated at 40 kVp. At a tube current of 100 Ma the element was given a 0.6 second exposure (60 Mas) whereupon an excellent image was obtained when the film was developed in a Kodak M-6 automatic processor at 33C. containing a standard p-N- methylamino hydrosulfate/hydroquinone X-ray developer, with the total processing time of 90 seconds (develop, fix, wash and dry). In comparison, an industrial X-ray film (300 mg. AgBr/dm without an intensifying screen, required an exposure up to 600 Mas to achieve the same image quality and additionally could not be machine processed under fast access conditions. Also, because the film/screen combination of this invention achieves the required contrast at lower film densities (known as the toe portion of the H&D curve) the image could be evaluated on a normal view box while the industrial film (presently used for mammographic work) needed a high intensity viewing light source to see the fine details. The use of high intensity viewing light is unpleasant for the viewer. If instead of the phantom a live, human subject had been employed, due to the increased exposure time necessary with the nonscreened element, involuntary patient movement (heart beat, etc.) would have reduced the sharpness of this element so othat the screened version would have had diagnostic value superior to the non-screened element. On the other hand, using a screen or screens with the double coated X-ray element would result in poor definition and lower image clarity due to mottle and print-through.

EXAMPLE 2 Several film/screen combinations were evaluated under the exposure-development conditions described in Example 1, and the results are shown below where a low value indicatesincreased diagnostic information and a high number indicates unsharpness or mottle:

Exposure Image Required Evalu- Film Screen (Mas) ation Industrial X-ray None 600 1 (double coated) Same as Ex. 1 Screen from 60 1 Ex. 1. Speed Factor 3.] Same as Ex. I but 2 screens of 50 3-4 emul. coated 1% Ex. I on each side Same as Ex. 1 BaPbSOAMedium 30 4 Speed) Screen Speed Factor 5.8 Same as Ex. 1 BaPbSO, (Low 1-2 Speed, High Detail) Screen Speed Factor 0.6 Commercial Double BaPbSO, (Medium 10-20 4 Coated High Speed Speed) Screen Medical X-ray Speed Factor 5.8 Commercial Double Screen From Ex. 1 l0-20 4 Coated High Speed Medical X-ray Speed Factor 5.1

NOTE: l-2 appear acceptable while 3-4 are considered unacceptable.

This example demonstrates that the specific screenfilm combination of this invention is required to produce the best results at the lowest patient exposure. Faster, more grainy film (e.g., commercial high speed medical X-ray film) will not give quality results. Screens with higher or lower speed factors also result in a poor image while many non-screen systems require 10 fold exposure and cannot be machine processed using fast access conditions.

EXAMPLE 3 shield to cover all but about a 3'4 inch strip across the cassette containing the film. This lead is moved after each exposureto present a new, unexposed strip of film to the radiation. At least 5 exposures are made varying the exposure time so that the first strip exposed had a total of 8/10 seconds, the second 4/10 seconds, the third 2/10 seconds, the fourth 1/10 seconds and the fifth 1/20 seconds giving a resulting exposure of 160, 80, 40 20 and 10 milliamp-seconds (Mas). The exposed film was developed as described above and the densities of the various exposures were read and plotted on log paper with the X axis being exposure and the Y axis being density. A curve was drawn through these points and the exposure necessary to get'D 1.00 was read from this curve. In this case, it was 64 Mas. Thus steps were repeated for a second sheet of film but including the screen of this invention. The tube current was lowered to 25 Ma and the exposure times were 4/10, 2/10, l/l0, U20 and 1/40 seconds giving 10, 5, 2.5, 1.25 and 0.625 Mas respectively. D 1.00 was reached at 8 Mas. The speed factor was calculated from the formula logm E2 I0810 E where [5 exposure required to give unit film density without a screen 64 Mas and E exposure required to give unit film density with a screen 8 Mas What is claimed is:

1. A radiographic element comprising a film support bearing a single silver halide emulsion layer and an antihalation layer, said silver halide emulsion having an average silver halide grain size of 0.4 to 1.2 microns, and an X-ray intensifying screen in contact with said emulsion layer, said emulsion layer and screen having a speed factor between 2.5 and 4.5.

2. A radiographic element of claim 1 wherein the silver halide average grain size is about one micron.

3. A radiographic element of claim 1 wherein the speed factor is between 3.0 and 4.2.

4. A radiographic element of claim 1 wherein said emulsion layer and screen are held in intimate contact in an evacuated vacuum cassette.

5. A radiographic element of claim 1 wherein said element has a modulation transfer function of at least 67.5 at 2 cycles per mm.

6. A method of making fine detail radiographs with low X-ray exposure comprising exposing the element of claim 1 to X-radiation.

7. A method according toclaim 6 of making mammographic radiographs with fine detail at low exposure levels comprising exposing said element to X-radiation through a human female breast.

8; A method of claim 6 wherein exposing said element to X-rays in an amount between 4 to 20 milliampere seconds at a distance of 40 inches is capable of producing a developed image density of 1.0 on said silver halide emulsion layer.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US3364029 *Jul 16, 1964Jan 16, 1968Eastman Kodak CoPhotographic antihalation components
US3412244 *Jan 17, 1966Nov 19, 1968Eastman Kodak CoFolded flexible vacuum exposure holder for radiography
US3617285 *Oct 21, 1969Nov 2, 1971Eastman Kodak CoLight intensifying screens
US3753714 *Nov 23, 1970Aug 21, 1973Fuji Photo Film Co LtdImage formation by radiation and intensification
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US4012637 *May 5, 1975Mar 15, 1977General Electric CompanyRadiographic screen with improved resolution
US4040833 *Apr 2, 1976Aug 9, 1977Fuji Photo Film Co., Ltd.Cyanine dyes
US4130428 *Oct 20, 1975Dec 19, 1978Agfa-Gevaert, N.V.Combination of photosensitive elements suited for use in radiography
US4130429 *Oct 20, 1975Dec 19, 1978Agfa-Gevaert, N.V.Combination of photosensitive elements suited for use in radiography
US4172730 *Apr 15, 1977Oct 30, 1979Fuji Photo Film Co., Ltd.Cyanine dye sensitizers, fluorescent intensifier screens
US4177071 *Sep 12, 1977Dec 4, 1979Agfa-Gevaert, N.V.Rapidly processable radiographic materials
US4195996 *Feb 28, 1978Apr 1, 1980Fuji Photo Film Co., Ltd.Method of recording radiation image
US4680252 *Jul 19, 1985Jul 14, 1987Konishiroku Photo Industry Co., Ltd.Silver halide light-sensitive photographic material for radiographic use
US4707435 *Apr 13, 1983Nov 17, 1987Minnesota Mining And Manufacturing CompanyIndustrial X-ray system
US4868399 *May 29, 1986Sep 19, 1989The Cancer Institute BoardMethod and apparatus for high energy radiography
US5463224 *Jul 1, 1986Oct 31, 1995American Science And Engineering, Inc.X-ray detector suited for high energy applications with wide dynamic range, high stopping power and good protection for opto-electronic transducers
US6021173 *Mar 30, 1998Feb 1, 2000U.S. Philips CorporationX-ray apparatus with sensor matrix
EP0232888A2 *Feb 9, 1987Aug 19, 1987EASTMAN KODAK COMPANY (a New Jersey corporation)High efficiency fluorescent screen pair for use in low energy X radiation imaging
EP0661592A1 *Dec 29, 1993Jul 5, 1995Minnesota Mining And Manufacturing CompanySymmetrical radiographic assembly for chest examination
WO1986007170A1 *May 29, 1986Dec 4, 1986Cancer Inst BoardMethod and apparatus for high energy radiography
Classifications
U.S. Classification430/139, 430/510, 430/523, 430/967, 430/567, 378/37, 250/475.2, 250/483.1, 430/966
International ClassificationG03C5/17, G03B42/04
Cooperative ClassificationG03B42/04, Y10S430/167, G03C5/17, Y10S430/168
European ClassificationG03C5/17, G03B42/04