|Publication number||US462990 A|
|Publication date||Nov 10, 1891|
|Filing date||Sep 23, 1891|
|Publication number||US 462990 A, US 462990A, US-A-462990, US462990 A, US462990A|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (29), Classifications (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
GAPSULE. i No. 462,990. Patented Nov. 10, 18911..
fy/ @2 193.- @f4 j l j j i@ @f @1% Y 3 l j s @d je'g Jyf z '1 .e j o., f o
I? .9, Ij, I" jj. 'j
yi 71 W j@ za'ge jfzyj 1 j j j UNITED STATES PATENT OFFICE.
VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE.
SPECIFICATION forming part'of Letters Patent No. 462,990, dated November 10, 1891..
Application filed September 23, 1891l Serial No. 398,711. (No specimens.) Patented in England January 29, 1891, No.1,651.
To L ZZ whom it may concern.-
Be it known that I, WILLIAM OPPENIIEIMEE, manufacturing chemist, a subject of the Queen of Great Britain, residing at 1 and 3 Sun Street and 39 XVilsonStreet, Finsbury Square, London, England, have invented a certain new and useful Improvement in Capsules and in the preparation of the same for use, (for which I have applied for a patent in Great Britain, No. 1,651, bearing,` date January 29, 1891,) of which the followingr is a specification.
My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain `the-different kinds of Inedieine.
The invention is illustrated by the accompanying drawings, in Which- Figure 1 is a transverse sectional view 0f a capsuleeinbodying my invention. Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.
In carrying` out my invention I make up the compound medicines as capsules, Waters,
pills, or granules 1, of any convenient form,
such as the lentil or double-convex lens or globular, semi-globular, double globular, or of any other preferred shape.
The capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine. The Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines. The inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.
The medicines so prepared as herein described Inay, if preferred, be dissolved or mixed in water or other suitable fluid or matter and taken as a draft.
I claim- A capsuleconsisting;` of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.
Dated this 16th day of June, 189l.
GEORGE F. DOWNING, SQual'z'ty Oom, London, W. O.
JOSEPH LAKE, 17 Gracechurch Street, London, E. C.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US2452273 *||Aug 20, 1945||Oct 26, 1948||Sant Robert H Van||Applicator|
|US2473368 *||Feb 25, 1944||Jun 14, 1949||Gerhard Flintermann||Suppository|
|US2497212 *||Oct 31, 1945||Feb 14, 1950||Alfonso M Donofrio||Method of manufacturing capsules|
|US2768115 *||Nov 2, 1951||Oct 23, 1956||Bristol Lab Inc||Penicillin-aspirin tablets|
|US3046605 *||Jan 12, 1960||Jul 31, 1962||American Cyanamid Co||Manufacture of two-color and two-tone soft shell capsules|
|US3087606 *||Oct 19, 1953||Apr 30, 1963||Minnesota Mining & Mfg||Package of inter-reactive materials|
|US3345265 *||Oct 9, 1963||Oct 3, 1967||Kendall & Co||Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating|
|US3844285 *||Dec 14, 1972||Oct 29, 1974||Commw Scient Ind Res Org||Device for administration to ruminants|
|US3922338 *||Jul 10, 1974||Nov 25, 1975||Choay Sa||Tablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets|
|US4139589 *||Oct 25, 1977||Feb 13, 1979||Monique Beringer||Process for the manufacture of a multi-zone tablet and tablet manufactured by this process|
|US4198390 *||Jan 31, 1979||Apr 15, 1980||Rider Joseph A||Simethicone antacid tablet|
|US4260596 *||Aug 13, 1979||Apr 7, 1981||Bristol-Myers Company||Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same|
|US4563358 *||Jan 29, 1979||Jan 7, 1986||F. B. Mercer Limited||Composite food product and method for making the same|
|US4793493 *||Aug 5, 1987||Dec 27, 1988||Makiej Jr Walter J||Multidose capsules|
|US4850489 *||Dec 22, 1988||Jul 25, 1989||Hoechst Aktiengesellschaft||Dispensing packs containing pharmaceutical combinations for sequential administration|
|US5074426 *||Jun 27, 1989||Dec 24, 1991||Warner-Lambert Company||Dividable capsule|
|US5314696 *||Jun 27, 1991||May 24, 1994||Paulos Manley A||Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor|
|US5558878 *||Apr 15, 1994||Sep 24, 1996||Captab, L.L.C.||Method for blinding a tableted medication|
|US5576019 *||Jun 7, 1995||Nov 19, 1996||Captab 11C||Method for blinding a medication|
|US5824338 *||Aug 19, 1996||Oct 20, 1998||L. Perrigo Company||Caplet and gelatin covering therefor|
|US6428770 *||Dec 3, 1997||Aug 6, 2002||Kao Corporation||Solid preparation for oral hygiene|
|US8920856||Oct 7, 2010||Dec 30, 2014||Intercontinental Great Brands Llc||Co-extruded layered candy and gum apparatus and methods|
|US9060526||Jan 22, 2010||Jun 23, 2015||Intercontinental Great Brands Llc||Confectionery processing|
|US20110003655 *||Jul 1, 2009||Jan 6, 2011||Chernick Mark J||Segmented High-Bounce Toy Water Ball|
|USD766014 *||Sep 15, 2014||Sep 13, 2016||Jin-Young Choi||Pillow for baby|
|CN102151410A *||Feb 11, 2010||Aug 17, 2011||马克·J·切尔尼克||Toy ball|
|WO1987006128A1 *||Feb 24, 1987||Oct 22, 1987||Clemetson Ab Charles||Catechin coated ascorbic acid and method|
|WO1999025629A1 *||Nov 16, 1998||May 27, 1999||Merck & Co., Inc.||Multicompartment container for combination products|
|WO2010096558A1||Feb 18, 2010||Aug 26, 2010||Eyeon Particle Sciences Llc||Bi-functional co-polymer use for ophthalmic and other topical and local applications|