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Publication numberUS462990 A
Publication typeGrant
Publication dateNov 10, 1891
Filing dateSep 23, 1891
Publication numberUS 462990 A, US 462990A, US-A-462990, US462990 A, US462990A
InventorsWilliam Oppenheimek
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
William oppenheimek
US 462990 A
Abstract  available in
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)

(No Model.)


GAPSULE. i No. 462,990. Patented Nov. 10, 18911..

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SPECIFICATION forming part'of Letters Patent No. 462,990, dated November 10, 1891..

Application filed September 23, 1891l Serial No. 398,711. (No specimens.) Patented in England January 29, 1891, No.1,651.

To L ZZ whom it may concern.-

Be it known that I, WILLIAM OPPENIIEIMEE, manufacturing chemist, a subject of the Queen of Great Britain, residing at 1 and 3 Sun Street and 39 XVilsonStreet, Finsbury Square, London, England, have invented a certain new and useful Improvement in Capsules and in the preparation of the same for use, (for which I have applied for a patent in Great Britain, No. 1,651, bearing,` date January 29, 1891,) of which the followingr is a specification.

My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain `the-different kinds of Inedieine.

The invention is illustrated by the accompanying drawings, in Which- Figure 1 is a transverse sectional view 0f a capsuleeinbodying my invention. Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.

In carrying` out my invention I make up the compound medicines as capsules, Waters,

pills, or granules 1, of any convenient form,

such as the lentil or double-convex lens or globular, semi-globular, double globular, or of any other preferred shape.

The capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine. The Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines. The inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.

The medicines so prepared as herein described Inay, if preferred, be dissolved or mixed in water or other suitable fluid or matter and taken as a draft.

I claim- A capsuleconsisting;` of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.

Dated this 16th day of June, 189l.



GEORGE F. DOWNING, SQual'z'ty Oom, London, W. O.

JOSEPH LAKE, 17 Gracechurch Street, London, E. C.

Referenced by
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US2452273 *Aug 20, 1945Oct 26, 1948Sant Robert H VanApplicator
US2473368 *Feb 25, 1944Jun 14, 1949Gerhard FlintermannSuppository
US2497212 *Oct 31, 1945Feb 14, 1950Alfonso M DonofrioMethod of manufacturing capsules
US2768115 *Nov 2, 1951Oct 23, 1956Bristol Lab IncPenicillin-aspirin tablets
US3046605 *Jan 12, 1960Jul 31, 1962American Cyanamid CoManufacture of two-color and two-tone soft shell capsules
US3087606 *Oct 19, 1953Apr 30, 1963Minnesota Mining & MfgPackage of inter-reactive materials
US3345265 *Oct 9, 1963Oct 3, 1967Kendall & CoMultiple layer tablet with calcium salt central core separated from soluble fluoride outer coating
US3844285 *Dec 14, 1972Oct 29, 1974Commw Scient Ind Res OrgDevice for administration to ruminants
US3922338 *Jul 10, 1974Nov 25, 1975Choay SaTablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets
US4139589 *Oct 25, 1977Feb 13, 1979Monique BeringerProcess for the manufacture of a multi-zone tablet and tablet manufactured by this process
US4198390 *Jan 31, 1979Apr 15, 1980Rider Joseph ASimethicone antacid tablet
US4260596 *Aug 13, 1979Apr 7, 1981Bristol-Myers CompanyEdible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
US4563358 *Jan 29, 1979Jan 7, 1986F. B. Mercer LimitedComposite food product and method for making the same
US4793493 *Aug 5, 1987Dec 27, 1988Makiej Jr Walter JMultidose capsules
US4850489 *Dec 22, 1988Jul 25, 1989Hoechst AktiengesellschaftDispensing packs containing pharmaceutical combinations for sequential administration
US5074426 *Jun 27, 1989Dec 24, 1991Warner-Lambert CompanyDividable capsule
US5314696 *Jun 27, 1991May 24, 1994Paulos Manley AMethods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
US5558878 *Apr 15, 1994Sep 24, 1996Captab, L.L.C.Method for blinding a tableted medication
US5576019 *Jun 7, 1995Nov 19, 1996Captab 11CMethod for blinding a medication
US5824338 *Aug 19, 1996Oct 20, 1998L. Perrigo CompanyCaplet and gelatin covering therefor
US6428770 *Dec 3, 1997Aug 6, 2002Kao CorporationSolid preparation for oral hygiene
US8920856Oct 7, 2010Dec 30, 2014Intercontinental Great Brands LlcCo-extruded layered candy and gum apparatus and methods
US9060526Jan 22, 2010Jun 23, 2015Intercontinental Great Brands LlcConfectionery processing
US20110003655 *Jul 1, 2009Jan 6, 2011Chernick Mark JSegmented High-Bounce Toy Water Ball
USD766014 *Sep 15, 2014Sep 13, 2016Jin-Young ChoiPillow for baby
CN102151410A *Feb 11, 2010Aug 17, 2011马克J切尔尼克Toy ball
WO1987006128A1 *Feb 24, 1987Oct 22, 1987Clemetson Ab CharlesCatechin coated ascorbic acid and method
WO1999025629A1 *Nov 16, 1998May 27, 1999Merck & Co., Inc.Multicompartment container for combination products
WO2010096558A1Feb 18, 2010Aug 26, 2010Eyeon Particle Sciences LlcBi-functional co-polymer use for ophthalmic and other topical and local applications
Cooperative ClassificationA61K9/4858