|Publication number||US4878905 A|
|Application number||US 07/230,686|
|Publication date||Nov 7, 1989|
|Filing date||Aug 10, 1988|
|Priority date||Feb 7, 1986|
|Publication number||07230686, 230686, US 4878905 A, US 4878905A, US-A-4878905, US4878905 A, US4878905A|
|Inventors||Karl G. Blass|
|Original Assignee||Blass Karl G|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (11), Referenced by (174), Classifications (9), Legal Events (7)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This application is a continuation of application Ser. No. 011,476, filed Feb. 5, 1987, now abandoned.
The invention described herein relates to a new and useful collapsible ellipsoidal or spherical gastric anchoring device. The device permits non-surgical implantation of gastrointestinal modules containing slow release medicaments, bound enzymes, nonpathogenic microorganisms, including buffers, cofactors and/or absorbents as required.
The gastrointestinal module consists of an ellipsoidal or spherical gastric anchor, a tether device and an intestinal payload module. All three components may of course be constructed as one seamless unit. The gastric anchor is a collapsible device containing two, three or more ribs which come together at the top dome. The opposite ends of the ribs fasten to a loop at the bottom. The tether attaches to the underside of the dome and passes through the bottom loop. The intestinal payload module in turn is fastened to the end of the tether. The intestinal module will likely be long and narrow somewhat resembling a tapeworm.
In accordance with the invention there is provided a gastrointestinal module consisting of a collapsible ellipsoidal or spherical gastric anchor with an attached tether device and an intestinal payload module secured to said tether, said intestinal payload module being designed to alter biochemical processes within the intestine. Means are provided for maintaining the components in the collapsed condition until implanted and may take the form of encapsulating said component individually in a material such as gelatin .
The principal advantage of the invention is to be able to implant or emplace a gastrointestinal module without surgery, said module being disposable.
Another advantage of the invention is to provide a device of the character herewithin described which is simple in construction, economical in manufacture and otherwise well suited to the purpose for which it is designed.
With the foregoing in view and other advantages as will become apparent to those skilled in the art to which this invention relates as this specification proceeds, the invention is herein described by reference to the accompanying drawings forming a part hereof, which includes a description of the best mode known to the applicant and of the preferred typical embodiment of the principles of the present invention, in which:
FIG. lA is a schematic side elevation of the invention shown in the expanded position.
FIG. lB is a fragmentary schematic representation of FIG. lA with the components shown in the collapsed or encapsulated position.
FIG. lC is a view similar to FIG. lB, but showing one method of implanting the module.
FIG. 2A is a schematic representation showing the device implanted with the components encapsulated or collapsed.
FIG. 2B is a view similar to FIG. 2A, but showing the components in the expanded emplaced position.
FIG. 3A is a partially schematic view of an alternative embodiment.
FIG. 3B is a fragmentary partially schematic view of a further embodiment.
FIG. 3C is a schematic representation showing a further embodiment of the anchor component.
FIG. 3D is a schematic representation showing a still further embodiment of the anchor component.
In the drawings like characters of reference indicate corresponding parts in the different figures.
Proceeding therefore to describe the invention in detail, the gastrointestinal module is collectively identified by reference character 10 and includes an anchor component collectively designated 11, an intestinal payload component collectively designated 12 and a flexible tether illustrated by reference character 13.
All of the components are preferably formed from a variety of medical grade plastics possessing desirable characteristics. These materials should, of course, be inert, stable and non-toxic to body fluids and tissues, and by way of example, one such material is trade-named "Silastic" and produced by the Dow Corning Corporation, Midland, Michigan.
The preferred embodiment of the gastric anchor 11 is shown in FIG. lA. It consists of a base ring 14 having a plurality of curved ribs 15 extending upwardly therefrom in spaced apart relationship, terminating in an apex 16 with the natural resiliency of the material forming an ellipsoidal configuration as clearly shown.
The tether 13 passes freely through the ring 14 and is secured by the upper end 17 to the aforementioned apex 16 of the ribs.
The intestinal payload component 12 is of an elongated flexible configuration similar to a tapeworm and contains the necessary materials designed to alter the biochemical processes within the intestine and to be released therefrom by various well-known means such as diffusion or the like through the wall of the component.
Prior to insertion, both components 11 and 12 are collapsed and maintained in the collapsed position until inserted within the gastric cavity and intestine respectively as will hereinafter be described.
Reference character 18 represents an encapsulating coating which maintains the components in the collapsed position illustrated schematically in FIG. lB and such an encapsulating coating may consist of gelatin which is dissolvable by hydrolysis once emplaced. Of course, other encapsulating materials may be used.
The components 11 and 12 together with the tether 13 may be formed as a one-piece unit and should, of course, be without seams or any projecting edges to minimize friction and to avoid damage to the tissues and the ribs 15 would of course be widely spaced so as not to restrict the passage of the nutrients into the intestine.
The device may be implanted via a gastric intubation technique as illustrated schematically, for example, in FIGS. 1C and 2A.
By way of example only, the intubation tube 19 of conventional construction may be forked at the insertion end and as illustrated by reference character 20. The long arm 21 of the forked end engaging the collapsed component 12 is passed through the sphincter shown schematically by reference character 22 while the shorter arm 23 engaging the anchor component 11 remains in the gastric cavity indicated by reference character 24. Reference character 25 indicates the intestine into which the payload component 12 is engaged.
Once the encapsulating material is dissolved, the payload module 12 would unfold in the intestine 25 while the gastric anchor component 11 would unfold within the stomach or gastric cavity 24 and take up the position shown in FIG. 2B.
This would release both the spherical anchor and the intestinal module from the gastric intubation tube 19 which would then be removed while the anchor component 11 would lodge itself prior to the sphincter 22 as shown in FIG. 2B, thus holding the intestinal payload module 12 by means of the tether device 13.
The intestinal module would exert a downward force upon the apex 16 of the gastric anchor component 11 via the tether 13 which force would assist in maintaining the spherical shape of the gastric anchor.
Furthermore, the ribs 15 of the gastric anchor component 11 would also act as shock absorbers for forces exerted by the intestinal component 12 and these anchor ribs 15 are so shaped as to distribute the anchoring forces over the gastric wall. Thus, the ribs should preferably be somewhat flattened and be without edges and seams to minimize friction and the like as hereinbefore discussed.
As mentioned previously, the intestinal component 12 may contain slow release medicaments, bound enzymes, cofactors, buffers, microorganisms and the like so that the biochemical processes of the intestine may be modified and in turn, may affect other body compartments.
When the treatment is completed, the gastrointestinal module may be removed with a conventional retrieval hook via a gastric intubation technique.
FIGS. 3B, 3C and 3D show the configuration of other anchor components llB, llC and llD respectively.
In FIG. 3B, the base ring is indicated by reference character 14B and the upwardly curving ribs by reference character 15B, terminating in the apex 16B to which the tether 13 is secured and depends downwardly freely through the ring 14B.
FIG. 3C shows a somewhat similar configuration with the base ring 14C and the curved ribs 15C which are more circular in configuration than the domed configuration shown in FIG. 3B.
In FIG. 3D, the ring is illustrated by reference character 14D with the domed ribs 15D being ellipsoidal and extending upon both sides of the ring.
FIG. 3A shows the ring at 14A with the flexible ribs 15A extending equally spaced around the ring terminating in the apex 16A and with the tether 13 being secured to the intestinal component 12, all of which is shown in the unfolded position.
Since various modifications can be made in my invention as hereinabove described, and many apparently widely different embodiments of same made within the spirit and scope of the claims without departing from such spirit and scope, it is intended that all matter contained in the accompanying specification shall be interpreted as illustrative only and not in a limiting sense.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1561020 *||Jul 25, 1922||Nov 10, 1925||Arthur H Smith||Frectal tampon|
|US2498692 *||Jan 4, 1949||Feb 28, 1950||Mains Marshall Paul||Gastrointestinal tube|
|US2671451 *||Jun 16, 1952||Mar 9, 1954||Bolger Stephen J||Remedial pill|
|US2773502 *||Dec 21, 1953||Dec 11, 1956||Kaslow Arthur L||Device for treating alimentary tract|
|US3312215 *||Aug 2, 1963||Apr 4, 1967||Silber Max N||Uterocervical cannula|
|US3483859 *||Nov 29, 1967||Dec 16, 1969||Pittman Fred E||String for marking bleeding in upper gastro-intestinal tract|
|US3811423 *||Jan 22, 1971||May 21, 1974||Agrophysics Inc||Device for insertion into the reproductive tract and method of using same|
|US4315509 *||Oct 16, 1978||Feb 16, 1982||Smit Julie A||Insertion and removal catheters and intestinal tubes for restricting absorption|
|US4531936 *||Jan 12, 1983||Jul 30, 1985||Gordon Robert T||Device and method for the selective delivery of drugs to the myocardium|
|US4687480 *||Sep 9, 1985||Aug 18, 1987||Commonwealth Scientific And Industrial Research Organization||Controlled release capsule|
|US4731054 *||Jun 20, 1986||Mar 15, 1988||Sulzer Brothers Limited||Medical repository probe|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US5167962 *||Aug 8, 1991||Dec 1, 1992||Southwest Research Institute||Filament system for delivering a medicament and method|
|US5383873 *||Dec 9, 1992||Jan 24, 1995||Regents Of The University Of Minnesota||Smooth muscle chemical pacemaker|
|US5433218 *||Dec 6, 1993||Jul 18, 1995||Dirk Wildemeersch||Intra-uterine device|
|US5498254 *||Jan 13, 1995||Mar 12, 1996||Regents Of The University Of Minnesota||Smooth muscle chemical pacemaker|
|US5591445 *||Oct 10, 1995||Jan 7, 1997||Regents Of The University Of Minnesota||Smooth muscle chemical pacemaker|
|US6139535 *||May 27, 1999||Oct 31, 2000||Situs Corporation||Method and apparatus for placement and activation of a medical device within a body cavity|
|US6171298||Mar 11, 1998||Jan 9, 2001||Situs Corporation||Intravesical infuser|
|US6183461||Sep 14, 1999||Feb 6, 2001||Situs Corporation||Method for delivering a medication|
|US7025791||Jan 9, 2003||Apr 11, 2006||Gi Dynamics, Inc.||Bariatric sleeve|
|US7054690||Oct 22, 2003||May 30, 2006||Intrapace, Inc.||Gastrointestinal stimulation device|
|US7066945||May 17, 2002||Jun 27, 2006||Wilson-Cook Medical Inc.||Intragastric device for treating obesity|
|US7083569||Aug 1, 2002||Aug 1, 2006||Zassi Medical Evolutions, Inc.||Ostomy cartridge|
|US7122058 *||Dec 2, 2003||Oct 17, 2006||Gi Dynamics, Inc.||Anti-obesity devices|
|US7258696 *||Jan 13, 2004||Aug 21, 2007||Intek Technology L.L.C.||Apparatus for delivering, repositioning and/or retrieving self-expanding stents|
|US7267694||Nov 30, 2004||Sep 11, 2007||Gi Dynamics, Inc.||Bariatric sleeve|
|US7314489||Aug 20, 2003||Jan 1, 2008||Ethicon Endo-Surgery, Inc.||Method and apparatus to facilitate nutritional malabsorption|
|US7329285||Nov 30, 2004||Feb 12, 2008||Gi Dynamics, Inc.||Bariatric sleeve delivery devices|
|US7347875||Nov 30, 2004||Mar 25, 2008||Gi Dynamics, Inc.||Methods of treatment using a bariatric sleeve|
|US7430450||Nov 16, 2005||Sep 30, 2008||Intrapace, Inc.||Device and method for treating obesity|
|US7476256||Jun 1, 2004||Jan 13, 2009||Gi Dynamics, Inc.||Intestinal sleeve|
|US7608114||Dec 13, 2005||Oct 27, 2009||Gi Dynamics, Inc.||Bariatric sleeve|
|US7676270||Nov 16, 2005||Mar 9, 2010||Intrapace, Inc.||Radially expandable gastrointestinal stimulation device|
|US7678068||Dec 13, 2005||Mar 16, 2010||Gi Dynamics, Inc.||Atraumatic delivery devices|
|US7682330||Jul 26, 2006||Mar 23, 2010||Gi Dynamics, Inc.||Intestinal sleeve|
|US7695446||Dec 13, 2005||Apr 13, 2010||Gi Dynamics, Inc.||Methods of treatment using a bariatric sleeve|
|US7699863||Sep 11, 2006||Apr 20, 2010||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US7758535||Dec 11, 2007||Jul 20, 2010||Gi Dynamics, Inc.||Bariatric sleeve delivery devices|
|US7766861||Oct 2, 2006||Aug 3, 2010||Gi Dynamics, Inc.||Anti-obesity devices|
|US7815589||Jun 1, 2004||Oct 19, 2010||Gi Dynamics, Inc.||Methods and apparatus for anchoring within the gastrointestinal tract|
|US7815591||Sep 16, 2005||Oct 19, 2010||Gi Dynamics, Inc.||Atraumatic gastrointestinal anchor|
|US7837643||Feb 14, 2005||Nov 23, 2010||Gi Dynamics, Inc.||Methods and devices for placing a gastrointestinal sleeve|
|US7883524||Dec 21, 2007||Feb 8, 2011||Wilson-Cook Medical Inc.||Method of delivering an intragastric device for treating obesity|
|US7931693 *||Nov 30, 2004||Apr 26, 2011||Endosphere, Inc.||Method and apparatus for reducing obesity|
|US7935073||Oct 29, 2007||May 3, 2011||Gi Dynamics, Inc.||Methods of treatment using a bariatric sleeve|
|US7967818||Jun 8, 2006||Jun 28, 2011||Cook Medical Technologies Llc||Cautery catheter|
|US7976488||Jun 8, 2005||Jul 12, 2011||Gi Dynamics, Inc.||Gastrointestinal anchor compliance|
|US7981163||Jan 8, 2010||Jul 19, 2011||Gi Dynamics, Inc.||Intestinal sleeve|
|US8007507||May 10, 2007||Aug 30, 2011||Cook Medical Technologies Llc||Intragastric bag apparatus and method of delivery for treating obesity|
|US8016851||Dec 27, 2007||Sep 13, 2011||Cook Medical Technologies Llc||Delivery system and method of delivery for treating obesity|
|US8048169||Apr 27, 2004||Nov 1, 2011||Baronova, Inc.||Pyloric valve obstructing devices and methods|
|US8057420||Dec 20, 2007||Nov 15, 2011||Gi Dynamics, Inc.||Gastrointestinal implant with drawstring|
|US8109920||Dec 12, 2007||Feb 7, 2012||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8118767||Sep 2, 2008||Feb 21, 2012||Laufer Michael D||Gastrointestinal implant and methods for use|
|US8137301||May 26, 2009||Mar 20, 2012||Gi Dynamics, Inc.||Bariatric sleeve|
|US8142513||Aug 22, 2007||Mar 27, 2012||Svip 2 Llc||Devices and methods for altering eating behavior|
|US8147561||Dec 15, 2005||Apr 3, 2012||Endosphere, Inc.||Methods and devices to curb appetite and/or reduce food intake|
|US8162871||May 26, 2009||Apr 24, 2012||Gi Dynamics, Inc.||Bariatric sleeve|
|US8216268||Dec 21, 2006||Jul 10, 2012||Cook Medical Technologies Llc||Intragastric bag for treating obesity|
|US8267888||Jul 22, 2010||Sep 18, 2012||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US8303573||Nov 29, 2007||Nov 6, 2012||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8303669||Sep 13, 2010||Nov 6, 2012||Gi Dynamics, Inc.||Methods and apparatus for anchoring within the gastrointestinal tract|
|US8323300||Jun 3, 2008||Dec 4, 2012||Svip 8 Llc||Tissue anchorable devices|
|US8333754||Dec 17, 2007||Dec 18, 2012||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8376981||Dec 22, 2009||Feb 19, 2013||Michael D. Laufer||Gastrointestinal implant and methods for use|
|US8403952||Dec 27, 2005||Mar 26, 2013||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US8414559||May 7, 2009||Apr 9, 2013||Rainbow Medical Ltd.||Gastroretentive duodenal pill|
|US8425451||Jun 2, 2011||Apr 23, 2013||Gi Dynamics, Inc.||Gastrointestinal anchor compliance|
|US8430894||Mar 28, 2007||Apr 30, 2013||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US8430895||May 16, 2011||Apr 30, 2013||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US8486153||Dec 8, 2006||Jul 16, 2013||Gi Dynamics, Inc.||Anti-obesity devices|
|US8540780||Mar 5, 2012||Sep 24, 2013||Svip 2 Llc.||Devices and methods for altering eating behavior|
|US8585771 *||May 25, 2007||Nov 19, 2013||Endosphere, Inc.||Methods and devices to curb appetite and/or to reduce food intake|
|US8597224||Mar 28, 2011||Dec 3, 2013||IBIS Medical, Inc.||Intragastric implant devices|
|US8603186||Mar 14, 2012||Dec 10, 2013||Endosphere, Inc.||Methods and devices to curb appetite and/or reduce food intake|
|US8623095||Apr 13, 2011||Jan 7, 2014||Endosphere, Inc.||Method and apparatus for reducing obesity|
|US8628583||Sep 14, 2012||Jan 14, 2014||Gi Dynamics, Inc.||Methods and apparatus for anchoring within the gastrointestinal tract|
|US8657885||Jan 9, 2009||Feb 25, 2014||Baronova, Inc.||Pyloric valve obstructing devices and methods|
|US8663338||Jan 9, 2009||Mar 4, 2014||Baronova, Inc.||Pyloric valve obstructing devices and methods|
|US8691271||Jan 25, 2008||Apr 8, 2014||Baronova, Inc.||Ingestible formulations for transient, noninvasive reduction of gastric volume|
|US8707964||Oct 31, 2007||Apr 29, 2014||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8771219||Oct 4, 2011||Jul 8, 2014||Gi Dynamics, Inc.||Gastrointestinal implant with drawstring|
|US8789536 *||Nov 27, 2007||Jul 29, 2014||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8795301||Jan 12, 2009||Aug 5, 2014||Baronova, Inc.||Device for intermittently obstructing a gastric opening and method of use|
|US8801647||Feb 21, 2008||Aug 12, 2014||Gi Dynamics, Inc.||Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks|
|US8808271||Dec 13, 2007||Aug 19, 2014||The Invention Science Fund I, Llc||Medical or veterinary digestive tract utilization systems and methods|
|US8808276||Oct 23, 2007||Aug 19, 2014||The Invention Science Fund I, Llc||Adaptive dispensation in a digestive tract|
|US8821429||Sep 29, 2009||Sep 2, 2014||IBIS Medical, Inc.||Intragastric implant devices|
|US8821521||Feb 5, 2007||Sep 2, 2014||Baronova, Inc.||Gastro-intestinal device and method for treating addiction|
|US8821584||Jan 12, 2009||Sep 2, 2014||Baronova, Inc.||Device for intermittently obstructing a gastric opening and method of use|
|US8834405||Jun 28, 2011||Sep 16, 2014||Gi Dynamics, Inc.||Intestinal sleeve|
|US8845673||Jul 22, 2010||Sep 30, 2014||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants and methods for use thereof|
|US8858496||Jul 22, 2010||Oct 14, 2014||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US8864784||Jul 22, 2010||Oct 21, 2014||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US8870806||May 2, 2011||Oct 28, 2014||Gi Dynamics, Inc.||Methods of treatment using a bariatric sleeve|
|US8882698||Mar 27, 2012||Nov 11, 2014||Gi Dynamics, Inc.||Anti-obesity devices|
|US8882749||Jun 2, 2009||Nov 11, 2014||Svip 8 Llc||Tissue-anchored devices|
|US8888797||Sep 5, 2008||Nov 18, 2014||Baronova, Inc.||Device for intermittently obstructing a gastric opening and method of use|
|US9060835||Jul 16, 2008||Jun 23, 2015||Endosphere, Inc.||Conformationally-stabilized intraluminal device for medical applications|
|US9072861||Feb 15, 2013||Jul 7, 2015||Endosphere, Inc.||Methods and devices for delivering or delaying lipids within a duodenum|
|US9084669||Dec 10, 2013||Jul 21, 2015||Gi Dynamics, Inc.||Methods and apparatus for anchoring within the gastrointestinal tract|
|US9095416||Jun 3, 2014||Aug 4, 2015||Gi Dynamics, Inc.||Removal and repositioning devices|
|US9155609||Feb 21, 2012||Oct 13, 2015||Gi Dynamics, Inc.||Bariatric sleeve|
|US9173734||Sep 26, 2012||Nov 3, 2015||IBIS Medical, Inc.||Intragastric implant devices|
|US9198791||Jul 20, 2011||Dec 1, 2015||Endobetix Ltd.||Pancreaticobiliary diversion device|
|US9237944||Jun 16, 2014||Jan 19, 2016||Gi Dynamics, Inc.||Intestinal sleeve|
|US9254214||Jan 4, 2013||Feb 9, 2016||Boston Scientific Scimed, Inc.||Satiation devices and methods|
|US9277921||Feb 15, 2013||Mar 8, 2016||Michael D. Laufer||Gastrointestinal implant and methods for use|
|US9278020||Oct 16, 2014||Mar 8, 2016||Gi Dynamics, Inc.||Methods of treatment using a bariatric sleeve|
|US9352126||Feb 15, 2013||May 31, 2016||Endosphere, Inc.||Methods and devices to curb appetite and/or reduce food intake|
|US9421246||Feb 12, 2014||Aug 23, 2016||Baronova, Inc.||Ingestible formulations for transient, noninvasive reduction of gastric volume|
|US9445791 *||Jun 8, 2012||Sep 20, 2016||Boston Scientific Scimed, Inc.||Systems and methods related to gastro-esophageal implants|
|US9452072||Jun 20, 2014||Sep 27, 2016||J. Mark Provenza||Apparatus and methods for anchoring in the stomach and the duodenum|
|US9492396||Jul 15, 2014||Nov 15, 2016||Yossi Gross||Enhanced drug delivery pill|
|US9498366||Aug 9, 2004||Nov 22, 2016||Baronova, Inc.||Devices and methods for pyloric anchoring|
|US9504591||Sep 24, 2014||Nov 29, 2016||Baronova, Inc.||Device for intermittently obstructing a gastric opening and method of use|
|US9510834||Jan 9, 2009||Dec 6, 2016||Baronova, Inc.||Gastric retaining devices and methods|
|US9526648||Mar 14, 2014||Dec 27, 2016||Synerz Medical, Inc.||Intragastric device for treating obesity|
|US9585783||May 13, 2015||Mar 7, 2017||Gi Dynamics, Inc.||Methods and apparatus for anchoring within the gastrointestinal tract|
|US9597215||Jul 12, 2013||Mar 21, 2017||Gi Dynamics, Inc.||Transpyloric anchoring|
|US9636245||Jul 12, 2013||May 2, 2017||Gi Dynamics, Inc.||Transpyloric anchoring|
|US20030040727 *||Aug 1, 2002||Feb 27, 2003||Jason Boulanger||Ostomy cartridge|
|US20040147939 *||Jan 13, 2004||Jul 29, 2004||Intek Technology, L.L.C.||Apparatus for delivering, repositioning and/or retrieving self-expanding stents|
|US20050033331 *||Apr 27, 2004||Feb 10, 2005||Polymorfix, Inc., C/O Medventure Associates||Pyloric valve obstructing devices and methods|
|US20050043817 *||Aug 20, 2003||Feb 24, 2005||Mckenna Robert Hugh||Method and apparatus to facilitate nutritional malabsorption|
|US20050090873 *||Oct 22, 2003||Apr 28, 2005||Imran Mir A.||Gastrointestinal stimulation device|
|US20050192614 *||Nov 30, 2004||Sep 1, 2005||Binmoeller Kenneth F.||Method and apparatus for reducing obesity|
|US20050197714 *||Mar 2, 2004||Sep 8, 2005||Sayet Peter H.||System, system devices, and methods for regulating nutrient absorption and caloric intake|
|US20060020278 *||Aug 29, 2005||Jan 26, 2006||Polymorfix, Inc.||Gastric retaining devices and methods|
|US20060142731 *||May 18, 2005||Jun 29, 2006||Jeffrey Brooks||Floating gastro-intestinal anchor|
|US20060155311 *||Dec 12, 2005||Jul 13, 2006||Kiyoshi Hashiba||Intragastric device for treating obesity|
|US20060178691 *||Dec 15, 2005||Aug 10, 2006||Binmoeller Kenneth F||Methods and devices to curb appetite and/or reduce food intake|
|US20070135831 *||Nov 20, 2006||Jun 14, 2007||Baronova, Inc.||Pyloric valve corking device|
|US20070156248 *||Sep 11, 2006||Jul 5, 2007||Doron Marco||Bioerodible self-deployable intragastric implants|
|US20070293885 *||May 25, 2007||Dec 20, 2007||Binmoeller Kenneth F||Methods and devices to curb appetite and/or to reduce food intake|
|US20080015523 *||Jul 19, 2007||Jan 17, 2008||Sentinel Group, Llc||Medical agent delivery system and method|
|US20080086082 *||Oct 8, 2007||Apr 10, 2008||Brooks Jeffrey S||Radiopaque marking to detect balloon deflation|
|US20080103604 *||Oct 29, 2007||May 1, 2008||Levine Andy H||Methods of treatment using a bariatric sleeve|
|US20080241094 *||Jan 25, 2008||Oct 2, 2008||Baronova, Inc.||Ingestible formulations for transient, noninvasive reduction of gastric volume|
|US20090062717 *||Sep 2, 2008||Mar 5, 2009||Laufer Michael D||Gastrointestinal implant and methods for use|
|US20090104250 *||Nov 27, 2007||Apr 23, 2009||Searete Llc, A Limited Liability Corporation Of The State Of Delaware||Medical or veterinary digestive tract utilization systems and methods|
|US20090110714 *||Dec 13, 2007||Apr 30, 2009||Searete Llc, A Limited Liability Corporation Of The State Of Delaware||Medical or veterinary digestive tract utilization systems and methods|
|US20090112189 *||Nov 26, 2007||Apr 30, 2009||Searete Llc||Medical or veterinary digestive tract utilization systems and methods|
|US20090112190 *||Dec 12, 2007||Apr 30, 2009||Searete Llc, A Limited Liability Corporation Of The State Of Delaware||Medical or veterinary digestive tract utilization systems and methods|
|US20090112191 *||Dec 17, 2007||Apr 30, 2009||Searete Llc, A Limited Liability Corporation Of The State Of Delaware||Medical or veterinary digestive tract utilization systems and methods|
|US20090118757 *||Jan 9, 2009||May 7, 2009||Burnett Daniel R||Pyloric valve obstructing devices and methods|
|US20090137866 *||Nov 28, 2007||May 28, 2009||Searete Llc, A Limited Liability Corporation Of The State Delaware||Medical or veterinary digestive tract utilization systems and methods|
|US20090182355 *||Dec 10, 2008||Jul 16, 2009||Levine Andy H||Porous barbs for long-term anchoring in the gastrointestinal tract|
|US20090192449 *||Oct 23, 2007||Jul 30, 2009||Seacrete Llc, A Limited Liability Corporation Of The State Of Delaware||Adaptive dispensation in a digestive tract|
|US20090247992 *||Aug 22, 2007||Oct 1, 2009||Svip 2 Llc||Devices and methods for altering eating behavior|
|US20090259236 *||Aug 29, 2005||Oct 15, 2009||Baronova, Inc.||Gastric retaining devices and methods|
|US20090287231 *||Mar 28, 2007||Nov 19, 2009||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US20100016871 *||Dec 27, 2005||Jan 21, 2010||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US20100049224 *||Sep 29, 2009||Feb 25, 2010||Jaime Vargas||Intragastric Implant Devices|
|US20100069819 *||Oct 10, 2006||Mar 18, 2010||Laufer Michael D||Minimally invasive gastrointestinal bypass|
|US20100121371 *||Apr 30, 2008||May 13, 2010||Spatz Fgia, Inc.||Non-endoscopic insertion and removal of a device|
|US20100137891 *||Jun 3, 2008||Jun 3, 2010||Svip 8Llc||Tissue anchorable devices|
|US20100191167 *||Dec 22, 2009||Jul 29, 2010||Lytn||Gastrointestinal implant and methods for use|
|US20100286745 *||Feb 3, 2010||Nov 11, 2010||Intrapace, Inc.||Radially Expandable Gastrointestinal Stimulation Device|
|US20110015665 *||Jul 22, 2010||Jan 20, 2011||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US20110015666 *||Jul 22, 2010||Jan 20, 2011||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US20110022072 *||Jul 22, 2010||Jan 27, 2011||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US20110040230 *||Mar 16, 2010||Feb 17, 2011||Laufer Michael D||Minimally invasive gastrointestinal bypass|
|US20110040318 *||Jul 22, 2010||Feb 17, 2011||Tulip Medical Ltd.||Bioerodible self-deployable intragastric implants|
|US20110092998 *||Oct 13, 2010||Apr 21, 2011||Spatz Fgia, Inc.||Balloon hydraulic and gaseous expansion system|
|US20110166556 *||Jun 2, 2009||Jul 7, 2011||Svip 8 Llc||Tissue-anchored devices|
|US20110190684 *||Apr 13, 2011||Aug 4, 2011||Binmoeller Kenneth F||Method and apparatus for reducing obesity|
|US20110213292 *||Sep 30, 2010||Sep 1, 2011||Laufer Michael D||Minimally invasive gastrointestinal bypass|
|US20110218563 *||May 16, 2011||Sep 8, 2011||Spatz-Fgia, Inc.||Floating gastrointestinal anchor|
|US20120041465 *||Oct 25, 2011||Feb 16, 2012||Tidhar Shalon||Devices and methods for treating gastrointestinal and metabolic disorders|
|US20130012863 *||Jun 8, 2012||Jan 10, 2013||Barosense, Inc.||Restrictive and/or obstructive implant system for inducing weight loss|
|CN103874468A *||Nov 1, 2012||Jun 18, 2014||内球公司||Duodenal gastrointestinal devices and related treatment methods|
|CN103874468B *||Nov 1, 2012||Oct 21, 2015||内球公司||十二指肠胃肠道装置|
|EP1979039A2 *||Feb 5, 2007||Oct 15, 2008||Baronova, Inc.||Gastro-intestinal device and method for treating addiction|
|EP1979039A4 *||Feb 5, 2007||Oct 30, 2013||Baronova Inc||Gastro-intestinal device and method for treating addiction|
|EP2397113A1 *||Aug 26, 2002||Dec 21, 2011||Synecor, LLC||Satiation devices|
|EP2773285A1 *||Nov 1, 2012||Sep 10, 2014||Endosphere, Inc.||Duodenal gastrointestinal devices and related treatment methods|
|EP2773285A4 *||Nov 1, 2012||Apr 29, 2015||Endosphere Inc||Duodenal gastrointestinal devices and related treatment methods|
|WO1991017745A1 *||May 22, 1991||Nov 28, 1991||Southwest Research Institute||Filament system for delivering a medicament and method|
|WO2002091961A1 *||May 17, 2002||Nov 21, 2002||Wilson-Cook Medical, Inc.||Intragastric device for treating obesity|
|WO2008023374A2 *||Aug 22, 2007||Feb 28, 2008||Svip 2 Llc||Devices and methods for altering eating behavior|
|WO2008023374A3 *||Aug 22, 2007||Apr 30, 2009||Svip 2 Llc||Devices and methods for altering eating behavior|
|WO2008121409A1 *||Mar 31, 2008||Oct 9, 2008||Jaime Vargas||Intragastric implant devices|
|WO2010125570A1 *||Apr 29, 2010||Nov 4, 2010||Svip 2 Llc||Devices and methods for treating gastrointestinal and metabolic disorders|
|WO2013067221A1||Nov 1, 2012||May 10, 2013||Endosphere, Inc.||Duodenal gastrointestinal devices and related treatment methods|
|U.S. Classification||604/891.1, 604/288, 604/285|
|International Classification||A61K9/20, A61K9/22|
|Cooperative Classification||A61K9/2072, A61F5/0036|
|European Classification||A61K9/20K, A61F5/00B6F|
|Jun 8, 1993||REMI||Maintenance fee reminder mailed|
|Oct 1, 1993||FPAY||Fee payment|
Year of fee payment: 4
|Oct 1, 1993||SULP||Surcharge for late payment|
|Nov 7, 1993||LAPS||Lapse for failure to pay maintenance fees|
|Jan 18, 1994||FP||Expired due to failure to pay maintenance fee|
Effective date: 19891107
|Apr 16, 1997||FPAY||Fee payment|
Year of fee payment: 8
|Apr 19, 2001||FPAY||Fee payment|
Year of fee payment: 12