Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS4917089 A
Publication typeGrant
Application numberUS 07/237,953
Publication dateApr 17, 1990
Filing dateAug 29, 1988
Priority dateAug 29, 1988
Fee statusPaid
Also published asDE68905990D1, DE68905990T2, EP0362113A1, EP0362113B1
Publication number07237953, 237953, US 4917089 A, US 4917089A, US-A-4917089, US4917089 A, US4917089A
InventorsEleftherios B. Sideris
Original AssigneeSideris Eleftherios B
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Buttoned device for the transvenous occlusion of intracardiac defects
US 4917089 A
Abstract
A transcatheter occluding intracardiac defect device comprises a folding poly-urethane foam with Teflon coated wire skeleton, introducible into a long vascular sheath and automatically unfolded upon delivery in the distal to the defect cardiac chamber. A two mm string loop is attached to the center of the occluder, while the loop is closed by a 1 mm knot. A loading wire comprises a Teflon hollow wire and a double mono-filament thread which carries the occluder on the one end and is tied on the other end. An occluder-holder comprises a rhomboid poly-urethane foam with Teflon coated wire skeleton and a "rubber" piece sutured in the center. The occluder-holder is advanced over the loading wire axis and through the long sheath in the proximal to the defect cardiac chamber and is pushed against the occluder till it is securely buttoned. The distal end of the loading wire is cut and the hollow wire is pulled out over the double thread. The thread is pulled as a single strand and therefore the device is released.
Images(2)
Previous page
Next page
Claims(3)
I claim:
1. An intracardiac percutaneously deliverable device for the repair of heart defects comprising:
a. an occluder, said occluder including:
i. a foldable foam polyurethane disc with
ii. a Teflon coated wire skeleton in the form of an "X" sutured to the foam disc, and
iii. a thread sutured to the center of the wire skeleton,
iv. said thread formed into a loop with
v. a knot closing the loop remote from the skeleton,
b. an occluder-holder, said occluder-holder including:
i. a foldable foam polyurethane rhomboid disc with
ii. a single wire skeleton sutured to the rhomboid disc, and
iii. a rubber piece sutured at the center of the rhomboid disc,
c. a loading wire including:
i. a Teflon coated hollow wire, and
ii. a long thread,
d. said loading wire pierced through an opening in the occluder-holder and its rubber piece,
e. said long thread extending
i. through the hollow wire,
ii. through the thread loop at the occluder, and
iii. back through the hollow wire;
f. so arranged and constructed that
i. the occluder-holder may be pushed toward the occluder and
ii. pulling on the loading wire will pull the knot through the rubber piece on the occluder-holder thereby
iii. buttoning the occluder-holder to the occluder.
2. The process of occluding a defect in a heart in which
a. an occluder is placed on one side of the defect and and
b. an occluder-holder is placed on the other side of the defect;
c. wherein an improved method of connecting the occluder and occluder-holder comprises:
d. before placing the occluder in the heart
i. attaching a loop of thread to the occluder,
ii. knotting the loop, and
iii. piercing the occluder-holder,
e. then after placing the occluder and occluder-holder in place
i. pulling the knot through the pierced occluder-holder thereby
ii. buttoning the occluder to the occluder-holder.
3. The invention as described in claim 2: wherein
f. said occluder-holder is pierced by a loading wire which
g. is used to place the occluder-holder,
h. then after the occluder holder is buttoned to the occluder:
i. cutting the loading wire,
ii. removing the loading wire, and
iii. removing a long doubled thread extending through the loop on the occluder by
iv. pulling one end of said doubled thread.
Description
BACKGROUND OF THE INVENTION

1. Field of the Invention

The present invention relates to an intracardiac prosthesis, and more particularly, concerns a transvenously deliverable prosthesis for the occlusion of intracardiac defects.

2. Description of the Prior Art

Intracardiac defects occur relatively uncommonly in children but can cause significant problems including congestive heart failure, pulmonary hypertension or even death. They are treated medically initially but quite frequently require surgical repair.

The surgical repair of intracardiac defects requires the use of general anesthesia, thoracotomy and heart-lung machine. It is associated with significant morbidity and mortality, pain for the child and a significant expense for the parents.

For these reasons attempts were made before to c1ose intracardiac defects without surgery. For example see King et al U.S. Pat. No. 3,874,388.

The late Dr. Rashkind invented an umbrella device with hooks on the inside. The umbrella was introduced by a long catheter in the distal to the defect chamber it would open there and then would be pulled against the septal wall by the catheter till it was well hooked. Subsequently, it was released.

The method did not become popular, because it was associated with complications. Dr. Rashkind invented also a hookless two disk device. However details of the specifications are not known and none of the above devices was patented.

We know though a great deal more about his double disk device, designed to occlude a vessel called patent ductus arteriosus. There are hooks involved and a bulky delivery system, requiring a very large for a child long sheath(llF or 3.7 mm for a 17 mm device).

SUMMARY OF THE INVENTION

The intracardiac prothesis of the present invention provides the means of the transvenous, without surgery, occlusion of intracardiac defects. The occlusion is achieved by two independently buttoned components, the occluder and the counter-occluder or occluder holder.

In a preferred embodiment of the occluder aspect of this invention, the polyurethane form with the X shape wire skeleton is folded so that the skeleton wires become nearly parallel. Thus the occluder can be introduced through a 7F(2.3 mm) or an 8F(2.7 mm) long sheath. The foam has a diameter of 2 mm, while the wire is size 0.018-0.025". The wire is Teflon covered in order not to be thrombogenic.

The occluder is dipped into Heparin solution before the introduction. At the center of the occluder a 2 mm long double loop is attached. The loop is closed by a 1 mm diameter knot. In actuality this knot will be the "button" during the attachment with the counter-occluder.

Another aspect of the present invention is the counter-occluder, or occluder holder. It is rhomboid in shape, made also by 2 mm thick poly-urethane foam and a single 0.018" wire of equal diameter to the occluder. Foam and wire are stitched together by a continuously run suture. A 2 mm rubber piece of rhomboid shape is sutured at the center of the occluder-holder. By applying two sutures along the rubber piece, the foam is covering the rubber, so there is no friction during the introduction and the advancement of the occluder-holder in the long sheath.

A further aspect of the present invention is the release or loading wire. It comprizes a Teflon coated hollow wire of a 0.028" wire and a double 0.005" Trilene thread, attached on the one end at already described occluder loop and tied on the other end of the hollow wire.

Trilene is a trademark and identifies a synthetic mono-filament fishing line or thread.

The loading or release hollow wire serves several purposes.

1. It is used to pull the occluder against the septum.

2. It is used to load the occluder-holder by threading the wire through the rubber center of the occluder-holder.

3. It is used as the axis of a pushing catheter and the long sheath, so the occluder-holder is pushed and is buttoned securely against the occluder.

4. It is used to release the device, by cutting its distal end, pulling the hollow wire over the double Trilene thread and then pulling the thread as a single strand.

In accordance with the principles of the present invention, the intracardiac prostheses hereof has significant advantages over known devices and specifically the Rashkind device and the King et al '388 device. It is miniaturized in size, requires a 7F(2.3 mm) or 8F(2.7 mm) sheath in comparison to a 15F(5.0 mm) sheath for the Rashkind device or a 23F(7.5 mm) sheath for a King et al device. It does not utilize hooks so it is not traumatic to the endocardium, or the conduction system. It conforms with the overall applicability of this intracardiac device to small children.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1. is a perspective view of the preferred embodiment of the intracardiac prosthesis part of the occluder, illustrated in the unfolded condition.

FIG. 2. is a perspective view of the preferred embodiment of the intracardiac prosthesis part of the occluder, illustrated in the folded condition, ready o be introduced in the long sheath.

FIG. 3. is a perspective view of the occluder connected through the central loop with the loading wire.

FIG. 4. is a perspective view of the intracardiac prosthesis part of the counter-occluder or occluder holder.

FIG. 5. is a cross-sectional view of the intracardiac device part of the occluder, connected to the loading wire and occluding an atrial septal defect.

FIG. 6. is a cross-sectional view of the intracardiac device part of the occluder-holder as it is introduced into the long sheath, over the loading wire.

FIG. 7 is a cross-sectional view of the occluder and occluder-holder parts of the device buttoned together and occluding the atrial septal defect.

FIG. 8. is a cross-sectional view of the detachment of the intracardiac device in the heart and removal of the loading wire and the long sheath.

DETAILED DESCRIPTION

While this invention is satisfied by embodiments in many forms, will herein be described in detail a preferred embodiment of the invention, with the understanding that the present disclosure is not intended to limit the invention to the embodiment illustrated.

Referring to the drawings, and FIG. 1 in particular, there is illustrated the preferred intracardiac prosthesis part, the occluder 10, of the present invention in the unfolded condition.

The occluder 10 is made by poly-urethane foam 16 lining 2 mm thick, with a diameter of 10 mm more than the diameter of the defect to be occluded. A Teflon coated wire skeleton 12 is introduced into the foam in an X shape and securely stitched to the foam by continuous and interrupted sutures.

A double loop thread or threaded loop 14 is securely attached at the center of the wire skeleton. The length of the loop is 2 mm and is closed by a knot of 1 mm in diameter.

In FIG. 2 which illustrates the occluder 10 folded, it becomes obvious how by applying gentle pressure on the edges of the wire skeleton between the thumb and the index finger, the occluder can be introduced into the long intravascular sheath 40. The long sheath can be as small as 7 or 8F in diameter so the device can be introduced through the vessels of small children.

Turning now to FIG. 3, the occluder 10 is connected to loading wire 28. The loading wire 28 consists of hollow wire 30 of a 0.028" Teflon coated wire and the double 005" Trilene mono-filament thread 32. The mono-filament thread 32 is passed through the "button" loop 14 attached to the occluder 10 and then through the hollow wire 30 in a double fashion. (FIGS. 3 and 6)

Mono-filament thread 32 is tightened several times at distal end 36, of the loading wire 28, so it is stretched inside the hollow wire 30.

A 3 cm thread end 38 is left after the knot at the distal end 36 in the mono-filament thread 32, to facilitate the future introduction of the occluder-holder 20 over the wire 28.

The loading wire 28 serves several purposes as it has been described before, pulling the occluder-10 against the septum, serving as the loading axis of the occluder-holder 20 and finally incorporating the release mechanism of the intracardiac device.

FIG. 4 describes the occluder-holder 20 which is also made by 2 mm thick foam 22. The length of the occluder-holder 20 is selected as equal to length of the occluder 10. Skeleton 26 is made by 0.018" Teflon coated wire to avoid clot formation. Wire 26 and foam 22 are stitched together by continuous and interrupting sutures.

On the center of the occluder-holder 20 a 2 mm rubber rhomboid rubber piece 24 is sutured. It serves several purposes. Firstly allows the occluder-holder 20 to be moved on the loading wire 28 axis without danger of dislodgement. Secondly it has elastic properties, so it is distended to allow the button knot 18 through. Thirdly it serves as the button-hole, so that it does not allow the knot 18 to un-button after detachment, thus holding the occluder 10 and occluder-holder 20 together.

Two stitches sutured along the rubber button allow the rubber 24 to be covered by foam 22. Thus, the friction is minimized during the introduction and the advancement into the long sheath 40.

FIG. 5 describes the introduction and the positioning of the occluder 10 inside the heart. The folded occluder is introduced as described before into the long sheath 40. A 7F end-hole catheter 34 is introduced over the loading wire 28 into the long sheath 40 and it is pushing the occluder 10 till it exits in the cardiac chamber distant to the cardiac defect. After the occluder 10 comes out from the long sheath 40, it is automatically unfolded and pulled gently with the loading wire 28 against the septal wall where the occluder is loosely attached.

FIG. 6 describes the introduction of the occluder-holder 20 inside the long sheath 40. The loading wire 28 is threaded through the center of the rubber piece 24 of the occluder-holder. The occluder-holder 20 is then advanced over the loading wire 28 and it is introduced into the long sheath 40 . The 7-F end-hole catheter 34 is introduced over the loading wire 28, pushing the occluder-holder, till it exits the long sheath 40 in the proximal to the defect cardiac chamber.

FIG. 7 illustrates the attachment of the occluder 10 to the occluder-holder 20. The occluder-holder has exited the sheath 40 and is pushed by the end-hole catheter 34 in a parallel fashion to the defect and the occluder, but still on the loading wire 28 axis. The loading wire is pulled gently, while the occluder-holder 20 is pushed by the end-hole catheter 34 and the end of the sheath 40. The actual "button" process involves the entry of the knot 18 of the occluder loop 14 into the rubber center 24 of the occluder-holder and the attachment by the "valve" like action.

FIG. 8 illustrates the detachment. The end of the loading wire 28 is cut. A sterilized pair of small pliers is used to cut the end of the hollow wire 30 and the tightened double 0.005" mono-filament thread 32 which are located outside the body. Thus they become detached from each other and they are removed with the following mechanism: The hollow wire 30 is pulled out over the double 0.005" mono-filament thread 32. The thread 32 is subsequently pulled out as a single strand, so that the device is detached inside the heart after the defect is occluded.

The present invention provides a percutaneous deliverable intracardiac prosthesis, suitable for treatment of various intracardiac defects, including atrial septal defect, ventricular septal defect and cardiac defects as parts of more complex lesions.

As an aid to correlating the terms of the claims to the exemplary drawing, the following catalog of elements and steps is provided:

10 occluder

12 skeleton

14 thread loop

16 polyurethane disc

18 knot

20 counter-occluder or occluder holder- rhomboid

22 polyurethane disc - (holder)

24 rubber piece - rhomboid

26 skeleton

28 loading wire

30 hollow wire or tube

32 Trilene thread

34 catheter

36 Distal end

38 Thread end

40 long sheath

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US3665926 *Apr 8, 1970May 30, 1972Bard Inc C RLigature and applicator therefor
US3786816 *Dec 21, 1972Jan 22, 1974TechnibioticsMethod and apparatus for occluding fluid flow through vessels
US3874388 *Feb 12, 1973Apr 1, 1975Ochsner Med Found AltonShunt defect closure system
Non-Patent Citations
Reference
1 *Rashkind Circulation vol. 67, No. 4, Apr. 1983, pp. 711 716.
2Rashkind-Circulation-vol. 67, No. 4, Apr. 1983, pp. 711-716.
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US5171259 *Mar 30, 1991Dec 15, 1992Kanji InoueDevice for nonoperatively occluding a defect
US5192301 *Sep 3, 1991Mar 9, 1993Nippon Zeon Co., Ltd.Closing plug of a defect for medical use and a closing plug device utilizing it
US5254133 *Apr 24, 1991Oct 19, 1993Seid Arnold SSurgical implantation device and related method of use
US5258000 *Nov 25, 1991Nov 2, 1993Cook IncorporatedTissue aperture repair device
US5284488 *Dec 23, 1992Feb 8, 1994Sideris Eleftherios BAdjustable devices for the occlusion of cardiac defects
US5333624 *Feb 24, 1992Aug 2, 1994United States Surgical CorporationSurgical attaching apparatus
US5334217 *May 14, 1993Aug 2, 1994Regents Of The University Of MinnesotaSeptal defect closure device
US5350399 *Oct 7, 1992Sep 27, 1994Jay ErlebacherPercutaneous arterial puncture seal device and insertion tool therefore
US5370650 *Jun 22, 1993Dec 6, 1994United States Surgical CorporationArticulating mesh deployment apparatus
US5405360 *Jul 22, 1993Apr 11, 1995United States Surgical CorporationResilient arm mesh deployer
US5425744 *Apr 18, 1994Jun 20, 1995C. R. Bard, Inc.Occluder for repair of cardiac and vascular defects
US5433727 *Aug 16, 1994Jul 18, 1995Sideris; Eleftherios B.Centering buttoned device for the occlusion of large defects for occluding
US5451235 *Apr 14, 1994Sep 19, 1995C.R. Bard, Inc.Occluder and method for repair of cardiac and vascular defects
US5507744 *Apr 30, 1993Apr 16, 1996Scimed Life Systems, Inc.Apparatus and method for sealing vascular punctures
US5507811 *Nov 15, 1994Apr 16, 1996Nissho CorporationProsthetic device for atrial septal defect repair
US5549633 *Aug 24, 1994Aug 27, 1996Kensey Nash CorporationApparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5578045 *Aug 2, 1994Nov 26, 1996Regents Of The University Of MinnesotaSeptal defect closure device
US5593422 *Jan 6, 1995Jan 14, 1997Muijs Van De Moer; Wouter M.Occlusion assembly for sealing openings in blood vessels and a method for sealing openings in blood vessels
US5620461 *Jan 5, 1995Apr 15, 1997Muijs Van De Moer; Wouter M.Sealing device
US5634936 *Feb 6, 1995Jun 3, 1997Scimed Life Systems, Inc.Device for closing a septal defect
US5681334 *Mar 7, 1996Oct 28, 1997Kensey Nash CorporationApparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5709707 *Nov 19, 1996Jan 20, 1998Children's Medical Center CorporationSelf-centering umbrella-type septal closure device
US5725552 *May 14, 1996Mar 10, 1998Aga Medical CorporationCollapsible medical device
US5728114 *Mar 7, 1996Mar 17, 1998Kensey Nash CorporationApparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5741297 *Aug 28, 1996Apr 21, 1998Simon; MorrisDaisy occluder and method for septal defect repair
US5792179 *May 28, 1997Aug 11, 1998Sideris; Eleftherios B.Device for occluding vascular system defects in a patient
US5797960 *Apr 20, 1995Aug 25, 1998Stevens; John H.Method and apparatus for thoracoscopic intracardiac procedures
US5810810 *Jun 6, 1995Sep 22, 1998Scimed Life Systems, Inc.Apparatus and method for sealing vascular punctures
US5823956 *May 7, 1996Oct 20, 1998Heartport, Inc.Method and apparatus for thoracoscopic intracardiac procedures
US5829447 *May 7, 1996Nov 3, 1998Heartport, Inc.To ablate cardiac tissue
US5846261 *Sep 8, 1997Dec 8, 1998Aga Medical Corp.Percutaneous catheter directed occlusion devices
US5853422 *Sep 23, 1997Dec 29, 1998Scimed Life Systems, Inc.Apparatus and method for closing a septal defect
US5855614 *May 7, 1996Jan 5, 1999Heartport, Inc.Method for closing a cardiac septal defect in a patient's heart
US5861003 *Oct 23, 1996Jan 19, 1999The Cleveland Clinic FoundationApparatus and method for occluding a defect or aperture within body surface
US5879366 *Dec 20, 1996Mar 9, 1999W.L. Gore & Associates, Inc.Self-expanding defect closure device and method of making and using
US5908428 *Sep 19, 1997Jun 1, 1999United States Surgical CorporationStitching devices for heart valve replacement surgery
US5916236 *Jan 7, 1997Jun 29, 1999Kensey Nash CorporationOcclusion assembly for sealing openings in blood vessels and a method for sealing openings in blood vessels
US5944738 *Feb 6, 1998Aug 31, 1999Aga Medical CorporationPercutaneous catheter directed constricting occlusion device
US5976174 *Dec 15, 1997Nov 2, 1999Ruiz; Carlos E.Medical hole closure device and methods of use
US6024096 *May 1, 1998Feb 15, 2000Correstore IncAnterior segment ventricular restoration apparatus and method
US6024756 *Dec 22, 1998Feb 15, 2000Scimed Life Systems, Inc.Method of reversibly closing a septal defect
US6029671 *May 22, 1996Feb 29, 2000Heartport, Inc.System and methods for performing endovascular procedures
US6063085 *Oct 22, 1993May 16, 2000Scimed Life Systems, Inc.Apparatus and method for sealing vascular punctures
US6077281 *Apr 22, 1999Jun 20, 2000Regents Of The University Of MinnesotaSeptal defect closure device
US6077291 *Nov 26, 1996Jun 20, 2000Regents Of The University Of MinnesotaSeptal defect closure device
US6113641 *Aug 24, 1998Sep 5, 2000Ethicon, Inc.Prosthesis for the obturation of a hernial canal
US6117159 *Dec 22, 1998Sep 12, 2000Scimed Life Systems, Inc.Apparatus and method for closing a septal defect
US6152144 *Nov 6, 1998Nov 28, 2000Appriva Medical, Inc.Method and device for left atrial appendage occlusion
US6171329Aug 28, 1998Jan 9, 2001Gore Enterprise Holdings, Inc.Self-expanding defect closure device and method of making and using
US6180848Aug 25, 1998Jan 30, 2001Ethicon, Inc.Prosthesis obturating device for the obturation of a hernial canal
US6206907May 7, 1999Mar 27, 2001Cardia, Inc.Occlusion device with stranded wire support arms
US6214029 *Apr 26, 2000Apr 10, 2001Microvena CorporationSeptal defect occluder
US6221104Jan 22, 1999Apr 24, 2001Cor Restore, Inc.Anterior and interior segment cardiac restoration apparatus and method
US6238416Nov 5, 1999May 29, 2001Eleftherios B. SiderisTranscatheter surgical patch
US6241768Aug 19, 1998Jun 5, 2001Ethicon, Inc.Prosthetic device for the repair of a hernia
US6269819Jun 25, 1998Aug 7, 2001The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US6270515Feb 26, 1997Aug 7, 2001Scimed Life Systems, Inc.Device for closing a septal defect
US6309350Oct 12, 1999Oct 30, 2001Tricardia, L.L.C.Pressure/temperature/monitor device for heart implantation
US6312446Sep 12, 2000Nov 6, 2001Scimed Life Systems, Inc.Apparatus and method for closing a septal defect
US6328757Apr 23, 1999Dec 11, 2001Robert G. MathenyDevice and method for performing surgery without impeding organ function
US6342064 *Dec 22, 1999Jan 29, 2002Nipro CorporationClosure device for transcatheter operation and catheter assembly therefor
US6346074Jun 12, 1996Feb 12, 2002Heartport, Inc.Devices for less invasive intracardiac interventions
US6368339May 19, 2000Apr 9, 2002Aga Medical CorporationMethod of forming medical devices: intra-vascular occlusion devices
US6379368 *May 13, 1999Apr 30, 2002Cardia, Inc.Occlusion device with non-thrombogenic properties
US6401720Oct 4, 1999Jun 11, 2002John H. StevensMethod and apparatus for thoracoscopic intracardiac procedures
US6425911May 25, 2001Jul 30, 2002Radi Medical Systems AbPositioning device and incision closure device
US6439237Jan 11, 2000Aug 27, 2002Correstore, Inc.Anterior segment coronary restoration apparatus and method
US6440152Jul 28, 2000Aug 27, 2002Microvena CorporationDefect occluder release assembly and method
US6450171Oct 11, 2000Sep 17, 2002Correstore, Inc.Anterior and inferior segment ventricular restoration apparatus and method
US6508828Nov 3, 2000Jan 21, 2003Radi Medical Systems AbSealing device and wound closure device
US6544167May 17, 2001Apr 8, 2003Correstore, Inc.Ventricular restoration patch
US6551303Oct 27, 1999Apr 22, 2003Atritech, Inc.Barrier device for ostium of left atrial appendage
US6551344Jan 12, 2001Apr 22, 2003Ev3 Inc.Septal defect occluder
US6596012Apr 18, 2001Jul 22, 2003Radi Medical Systems AbIntra-arterial occluder
US6596013Sep 20, 2001Jul 22, 2003Scimed Life Systems, Inc.Method and apparatus for treating septal defects
US6623508Jan 5, 2001Sep 23, 2003Gore Enterprise Holdings, Inc.Self-expanding defect closure device and method of making and using
US6629534Apr 7, 2000Oct 7, 2003Evalve, Inc.Methods and apparatus for cardiac valve repair
US6645143Sep 20, 2001Nov 11, 2003Tricardia, L.L.C.Pressure/temperature/flow monitor device for vascular implantation
US6651672Aug 28, 2001Nov 25, 2003Heartport, Inc.Devices for less-invasive intracardiac interventions
US6652555Aug 18, 2000Nov 25, 2003Atritech, Inc.Barrier device for covering the ostium of left atrial appendage
US6652556Oct 26, 2000Nov 25, 2003Atritech, Inc.Filter apparatus for ostium of left atrial appendage
US6656206 *Jan 23, 2002Dec 2, 2003Cardia, Inc.Occlusion device with non-thrombogenic properties
US6679268Mar 15, 2002Jan 20, 2004Heartport, Inc.Method and apparatus for thoracoscopic intracardiac procedures
US6681773May 24, 2001Jan 27, 2004Chase Medical, Inc.Kit and method for use during ventricular restoration
US6689150Jul 11, 2000Feb 10, 2004Atritech, Inc.Filter apparatus for ostium of left atrial appendage
US6702763May 24, 2001Mar 9, 2004Chase Medical, L.P.Sizing apparatus and method for use during ventricular restoration
US6730108Mar 27, 2003May 4, 2004Atritech, Inc.Barrier device for ostium of left atrial appendage
US6749622Oct 11, 2002Jun 15, 2004Rex Medical, L.P.Vascular closure
US6752813Jun 27, 2001Jun 22, 2004Evalve, Inc.Methods and devices for capturing and fixing leaflets in valve repair
US6770083Jul 24, 2002Aug 3, 2004Evalve, Inc.Surgical device for connecting soft tissue
US6790213Jan 7, 2002Sep 14, 2004C.R. Bard, Inc.Promotes tissue growth into the prosthesis and subsequently strengthens the area of the defect, such as tissue or muscle defect
US6837247Apr 8, 2003Jan 4, 2005Correstore, Inc.Method of using ventricular restoration patch
US6911037Mar 6, 2002Jun 28, 2005Ev3, Inc.Retrievable septal defect closure device
US6913614May 8, 2003Jul 5, 2005Cardia, Inc.Delivery system with safety tether
US6941169Jun 4, 2002Sep 6, 2005Albert Einstein Healthcare NetworkCardiac stimulating apparatus having a blood clot filter and atrial pacer
US6949107Jun 27, 2003Sep 27, 2005Rex Medical, LpInjection method for locating vessel lumen
US6949113Dec 3, 2002Sep 27, 2005Atritech, Inc.Barrier device for ostium of left atrial appendage
US6955175May 1, 2003Oct 18, 2005Stevens John HMethod and apparatus for thoracoscopic intracardiac procedures
US6959711Jun 5, 2003Nov 1, 2005Chase Medical, L.P.Kit and method for use during ventricular restoration
US6960220Jan 22, 2003Nov 1, 2005Cardia, Inc.Hoop design for occlusion device
US6994092Aug 15, 2003Feb 7, 2006Ev3 Sunnyvale, Inc.Device for containing embolic material in the LAA having a plurality of tissue retention structures
US6994093May 24, 2001Feb 7, 2006Chase Medical, L.P.Ventricular restoration shaping apparatus and method of use
US7011671Jul 16, 2002Mar 14, 2006Atritech, Inc.Cardiac implant device tether system and method
US7025756Jun 4, 2004Apr 11, 2006Ev 3 Sunnyvale, Inc.Method of securing tissue
US7044134Oct 19, 2001May 16, 2006Ev3 Sunnyvale, IncMethod of implanting a device in the left atrial appendage
US7056280Aug 7, 2002Jun 6, 2006Correstore, Inc.Anterior segment ventricular restoration apparatus and method
US7087072Jan 22, 2003Aug 8, 2006Cardia, Inc.Articulated center post
US7100614Mar 15, 2002Sep 5, 2006Heartport, Inc.Method of Forming a Lesion in Heart Tissue
US7101381Aug 2, 2002Sep 5, 2006C.R. Bard, Inc.Implantable prosthesis
US7115110Oct 30, 2003Oct 3, 2006Ev3 Sunnyvale, Inc.Method and apparatus for closing a body lumen
US7115135Jan 22, 2003Oct 3, 2006Cardia, Inc.Occlusion device having five or more arms
US7122043May 19, 2004Oct 17, 2006Stout Medical Group, L.P.Tissue distention device and related methods for therapeutic intervention
US7128073Nov 8, 1999Oct 31, 2006Ev3 Endovascular, Inc.Method and device for left atrial appendage occlusion
US7144410Sep 18, 2003Dec 5, 2006Cardia Inc.ASD closure device with self centering arm network
US7152605May 16, 2003Dec 26, 2006Ev3 Endovascular, Inc.Adjustable left atrial appendage implant deployment system
US7169164Sep 21, 2001Jan 30, 2007Atritech, Inc.Apparatus for implanting devices in atrial appendages
US7169168Aug 21, 2003Jan 30, 2007Kensey Nash CorporationSealing device
US7192435Sep 18, 2003Mar 20, 2007Cardia, Inc.Self centering closure device for septal occlusion
US7192439May 19, 2003Mar 20, 2007Ev3 Endovascular, Inc.Method of removing an implanted device
US7220265Jan 14, 2003May 22, 2007Nmt Medical, Inc.Patent foramen ovale (PFO) closure method and device
US7226467May 19, 2003Jun 5, 2007Evalve, Inc.Fixation device delivery catheter, systems and methods of use
US7267679Jan 16, 2003Sep 11, 2007Rex Medical, L.PVascular hole closure device
US7275546Mar 29, 2004Oct 2, 2007Buckberg Gerald DAnterior and inferior segment ventricular restoration apparatus and method
US7279007Aug 1, 2002Oct 9, 2007Cardioklnetix, Inc.Method for improving cardiac function
US7288097Jun 24, 2004Oct 30, 2007Evalve, Inc.Surgical device for connecting soft tissue
US7288105Jul 30, 2002Oct 30, 2007Ev3 Endovascular, Inc.Tissue opening occluder
US7303526 *Aug 1, 2002Dec 4, 2007Cardiokinetix, Inc.Device for improving cardiac function
US7318833Sep 12, 2003Jan 15, 2008Nmt Medical, Inc.PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US7338514Jun 1, 2001Mar 4, 2008St. Jude Medical, Cardiology Division, Inc.Closure devices, related delivery methods and tools, and related methods of use
US7341595Jun 5, 2002Mar 11, 2008Rex Medical, L.PVascular hole closure device
US7377936Aug 31, 2004May 27, 2008Ev3, Inc.Retrievable septal defect closure device
US7399271Jan 9, 2004Jul 15, 2008Cardiokinetix, Inc.Ventricular partitioning device
US7419498Sep 17, 2004Sep 2, 2008Nmt Medical, Inc.Quick release knot attachment system
US7427279Apr 10, 2006Sep 23, 2008Atritech, Inc.Method of closing an opening in a wall of a heart
US7431729Jun 5, 2003Oct 7, 2008Nmt Medical, Inc.Patent foramen ovale (PFO) closure device with radial and circumferential support
US7462188Sep 22, 2004Dec 9, 2008Abbott LaboratoriesDevice and method for suturing intracardiac defects
US7464712Apr 28, 2004Dec 16, 2008The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US7479155Aug 26, 2002Jan 20, 2009Ev3 Endovascular, Inc.Defect occluder release assembly and method
US7485088Sep 5, 2002Feb 3, 2009Chase Medical L.P.Method and device for percutaneous surgical ventricular repair
US7509959Jun 30, 2004Mar 31, 2009The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US7549983Nov 24, 2004Jun 23, 2009Atritech, Inc.Method of closing an opening in a wall of the heart
US7563267May 19, 2003Jul 21, 2009Evalve, Inc.Fixation device and methods for engaging tissue
US7563273Mar 17, 2004Jul 21, 2009Evalve, Inc.Methods and devices for capturing and fixing leaflets in valve repair
US7566336Nov 25, 2003Jul 28, 2009Cardia, Inc.Left atrial appendage closure device
US7572228Jan 12, 2005Aug 11, 2009Remon Medical Technologies LtdDevices for fixing a sensor in a lumen
US7575586Oct 9, 2003Aug 18, 2009St. Jude Medical Atg, Inc.Medical graft connector or plug structures, and methods of making and installing same
US7582051Jun 10, 2005Sep 1, 2009Cardiokinetix, Inc.Peripheral seal for a ventricular partitioning device
US7582103 *Nov 30, 2006Sep 1, 2009Ev3 Endovascular, Inc.Tissue opening occluder
US7582104Dec 8, 2004Sep 1, 2009Cardia, Inc.Daisy design for occlusion device
US7594886Jan 3, 2005Sep 29, 2009Correstore LlcMethod of using ventricular restoration patch
US7597704Apr 28, 2003Oct 6, 2009Atritech, Inc.Left atrial appendage occlusion device with active expansion
US7604646May 16, 2005Oct 20, 2009Evalve, Inc.Locking mechanisms for fixation devices and methods of engaging tissue
US7608091Jul 3, 2003Oct 27, 2009Evalve, Inc.Methods and apparatus for cardiac valve repair
US7635329Sep 27, 2005Dec 22, 2009Evalve, Inc.Methods and devices for tissue grasping and assessment
US7648532Jan 3, 2006Jan 19, 2010Septrx, Inc.Tissue distention device and related methods for therapeutic intervention
US7655015Dec 21, 2007Feb 2, 2010Evalve, Inc.Fixation devices, systems and methods for engaging tissue
US7658748Sep 23, 2003Feb 9, 2010Cardia, Inc.Right retrieval mechanism
US7662161May 17, 2004Feb 16, 2010Rex Medical, L.PVascular hole closure device
US7662168May 14, 2004Feb 16, 2010Rex Medical, L.P.Vascular closure
US7666204May 19, 2003Feb 23, 2010Evalve, Inc.Multi-catheter steerable guiding system and methods of use
US7674222Dec 14, 2006Mar 9, 2010Cardiokinetix, Inc.Cardiac device and methods of use thereof
US7678123Jul 14, 2004Mar 16, 2010Nmt Medical, Inc.Tubular patent foramen ovale (PFO) closure device with catch system
US7678132Jun 7, 2006Mar 16, 2010Ovalis, Inc.Systems and methods for treating septal defects
US7682319Feb 25, 2009Mar 23, 2010Evalve, Inc.Steerable access sheath and methods of use
US7682369Feb 14, 2006Mar 23, 2010Evalve, Inc.Surgical device for connecting soft tissue
US7686828Jun 7, 2006Mar 30, 2010Ovalis, Inc.Systems and methods for treating septal defects
US7691115Jun 19, 2006Apr 6, 2010Cardia, Inc.Occlusion device with flexible fabric connector
US7691128Oct 14, 2005Apr 6, 2010St. Jude Medical, Cardiology Division, Inc.PFO closure devices and related methods of use
US7704268Apr 21, 2005Apr 27, 2010Nmt Medical, Inc.Closure device with hinges
US7704269Aug 5, 2003Apr 27, 2010Evalve, Inc.Methods and apparatus for cardiac valve repair
US7713282Apr 28, 2003May 11, 2010Atritech, Inc.Detachable atrial appendage occlusion balloon
US7717937Aug 8, 2005May 18, 2010St. Jude Medical, Cardiology Division, Inc.Closure devices, related delivery methods and tools, and related methods of use
US7722641Dec 8, 2004May 25, 2010Atritech, Inc.Filter mesh for preventing passage of embolic material form an atrial appendage
US7727189Aug 19, 2003Jun 1, 2010Atritech, Inc.Filter apparatus for ostium of left atrial appendage
US7735493Aug 15, 2003Jun 15, 2010Atritech, Inc.System and method for delivering a left atrial appendage containment device
US7736388Jan 16, 2007Jun 15, 2010Evalve, Inc.Fixation devices, systems and methods for engaging tissue
US7740640May 28, 2004Jun 22, 2010Ovalis, Inc.Clip apparatus for closing septal defects and methods of use
US7749238Jun 19, 2006Jul 6, 2010Cardia, Inc.Occlusion device with flexible polymeric connector
US7753923Aug 25, 2004Jul 13, 2010Evalve, Inc.Leaflet suturing
US7758494Jun 5, 2006Jul 20, 2010Correstore, Inc.Anterior segment ventricular restoration apparatus and method
US7758596Oct 15, 2002Jul 20, 2010The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US7762943Mar 3, 2004Jul 27, 2010Cardiokinetix, Inc.Inflatable ventricular partitioning device
US7766820Oct 24, 2003Aug 3, 2010Nmt Medical, Inc.Expandable sheath tubing
US7780683Mar 26, 2004Aug 24, 2010Roue Chad CMethod of closing an opening in a wall of the heart
US7780687 *Apr 16, 2003Aug 24, 2010Tyco Healthcare Group LpMethod and apparatus for anastomosis including expandable anchor
US7780700Feb 4, 2004Aug 24, 2010ev3 Endovascular, IncPatent foramen ovale closure system
US7785334Aug 23, 2006Aug 31, 2010C.R. Bard, Inc.Implantable prosthesis
US7797056Sep 6, 2006Sep 14, 2010Nmt Medical, Inc.Removable intracardiac RF device
US7806905Apr 10, 2009Oct 5, 2010C.R. Bard, Inc.Implantable prosthesis
US7811296Oct 27, 2004Oct 12, 2010Evalve, Inc.Fixation devices for variation in engagement of tissue
US7824420May 26, 2004Nov 2, 2010C.R. Bard, Inc.Implantable prosthesis
US7837696Dec 5, 2003Nov 23, 2010Abbott LaboratoriesArticulating suturing device and method
US7842047Feb 27, 2006Nov 30, 2010Abbott LaboratoriesArticulating suturing device and method
US7842048Aug 18, 2006Nov 30, 2010Abbott LaboratoriesArticulating suture device and method
US7842049Oct 25, 2006Nov 30, 2010Abbott LaboratoriesSystems for anchoring a medical device in a body lumen
US7842053Mar 30, 2005Nov 30, 2010Nmt Medical, Inc.Double coil occluder
US7842069 *May 6, 2005Nov 30, 2010Nmt Medical, Inc.Inflatable occluder
US7846170Mar 20, 2007Dec 7, 2010Abbott LaboratoriesArticulating suturing device and method
US7846179Sep 1, 2005Dec 7, 2010Ovalis, Inc.Suture-based systems and methods for treating septal defects
US7850701Aug 2, 2004Dec 14, 2010Abbott LaboratoriesArticulating suturing device and method
US7857828Feb 1, 2005Dec 28, 2010Integrated Vascular Systems, Inc.Clip applier and methods of use
US7862500Jun 10, 2005Jan 4, 2011Cardiokinetix, Inc.Multiple partitioning devices for heart treatment
US7867250Dec 19, 2002Jan 11, 2011Nmt Medical, Inc.Septal occluder and associated methods
US7871419Mar 2, 2005Jan 18, 2011Nmt Medical, Inc.Delivery/recovery system for septal occluder
US7875052 *Dec 16, 2005Jan 25, 2011Terumo Kabushiki KaishaTissue closure and tissue closing device
US7883517Aug 8, 2005Feb 8, 2011Abbott LaboratoriesVascular suturing device
US7887477Nov 22, 2002Feb 15, 2011Cardiokinetix, Inc.Method of improving cardiac function using a porous membrane
US7887562Oct 29, 2007Feb 15, 2011Ev3 Endovascular, Inc.Tissue opening occluder
US7897086Sep 24, 2007Mar 1, 2011Cardiokinetix, Inc.Method of making a laminar ventricular partitioning device
US7905901Nov 29, 2004Mar 15, 2011Cardia, Inc.Self-centering occlusion device
US7914438Sep 28, 2009Mar 29, 2011Correstore LlcVentricular restoration patch
US7927351Jun 19, 2006Apr 19, 2011Cardia, Inc.Occlusion device with flexible wire connector
US7938827Mar 10, 2009May 10, 2011Evalva, Inc.Cardiac valve leaflet attachment device and methods thereof
US7942888Jan 3, 2006May 17, 2011Rex Medical, L.P.Vascular hole closure device
US7963952Aug 19, 2004Jun 21, 2011Wright Jr John AExpandable sheath tubing
US7967840Oct 10, 2007Jun 28, 2011Nmt Medical, Inc.PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US7972359Sep 16, 2005Jul 5, 2011Atritech, Inc.Intracardiac cage and method of delivering same
US7972361Jun 19, 2006Jul 5, 2011Cardia, Inc.Occlusion device with flexible spring connector
US7976455Jul 28, 2008Jul 12, 2011Cardiokinetix, Inc.Inflatable ventricular partitioning device
US7976564May 6, 2002Jul 12, 2011St. Jude Medical, Cardiology Division, Inc.PFO closure devices and related methods of use
US7981123Feb 3, 2010Jul 19, 2011Evalve, Inc.Surgical device for connecting soft tissue
US7981139Apr 11, 2006Jul 19, 2011Evalve, IncSuture anchors and methods of use
US7998151Aug 25, 2004Aug 16, 2011Evalve, Inc.Leaflet suturing
US8025495Aug 27, 2007Sep 27, 2011Cook Medical Technologies LlcApparatus and method for making a spider occlusion device
US8029518Oct 30, 2007Oct 4, 2011Evalve, Inc.Methods and devices for capturing and fixing leaflets in valve repair
US8029532Oct 9, 2007Oct 4, 2011Cook Medical Technologies LlcClosure device with biomaterial patches
US8034061Jul 12, 2007Oct 11, 2011Aga Medical CorporationPercutaneous catheter directed intravascular occlusion devices
US8038688Nov 14, 2005Oct 18, 2011Abbott LaboratoriesArticulating suturing device and method
US8043329May 15, 2006Oct 25, 2011Atritech, Inc.Method of implanting an adjustable occlusion device
US8048092Dec 6, 2010Nov 1, 2011Abbott LaboratoriesArticulating suturing device and method
US8052592Oct 7, 2009Nov 8, 2011Evalve, Inc.Methods and devices for tissue grasping and assessment
US8057399Sep 14, 2007Nov 15, 2011Cardiac Pacemakers, Inc.Anchor for an implantable sensor
US8057491Dec 13, 2010Nov 15, 2011Abbott LaboratoriesArticulating suturing device and method
US8057493Dec 18, 2009Nov 15, 2011Evalve, Inc.Fixation devices, systems and methods for engaging tissue
US8060214Jan 5, 2006Nov 15, 2011Cardiac Pacemakers, Inc.Implantable medical device with inductive coil configurable for mechanical fixation
US8070772Jan 23, 2009Dec 6, 2011Rex Medical, L.P.Vascular hole closure device
US8070826Dec 11, 2003Dec 6, 2011Ovalis, Inc.Needle apparatus for closing septal defects and methods for using such apparatus
US8080032Sep 30, 2003Dec 20, 2011Atritech, Inc.Method and device for left atrial appendage occlusion
US8083754Aug 8, 2005Dec 27, 2011Abbott LaboratoriesVascular suturing device with needle capture
US8083766Jul 7, 2006Dec 27, 2011Rex Medical, LpSeptal defect closure device
US8123703Feb 3, 2010Feb 28, 2012Evalve, Inc.Steerable access sheath and methods of use
US8128653Aug 17, 2007Mar 6, 2012Rex Medical, L.P.Vascular hole closure device
US8133238 *May 17, 2006Mar 13, 2012Terumo Kabushiki KaishaTissue closing device
US8133239Sep 12, 2008Mar 13, 2012The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US8137364Sep 11, 2003Mar 20, 2012Abbott LaboratoriesArticulating suturing device and method
US8167894Aug 8, 2007May 1, 2012Coherex Medical, Inc.Methods, systems and devices for reducing the size of an internal tissue opening
US8172860Dec 12, 2008May 8, 2012Abbott LaboratoriesArticulating suturing device and method
US8177809Sep 4, 2009May 15, 2012Curaseal Inc.Inflatable device for enteric fistula treatment
US8187299Oct 29, 2007May 29, 2012Evalve, Inc.Methods and apparatus for cardiac valve repair
US8192478Nov 10, 2008Jun 5, 2012Cardiokinetix, Inc.System for improving cardiac function
US8202281Nov 29, 2010Jun 19, 2012Abbott LaboratoriesSystems for anchoring a medical device in a body lumen
US8204599Apr 16, 2008Jun 19, 2012Cardiac Pacemakers, Inc.System for anchoring an implantable sensor in a vessel
US8206416Sep 28, 2009Jun 26, 2012Curaseal Inc.Inflatable device for enteric fistula treatment
US8211122Aug 9, 2007Jul 3, 2012Abbott LaboratoriesDevice for suturing intracardiac defects
US8216230Apr 4, 2011Jul 10, 2012Evalve, Inc.Cardiac valve leaflet attachment device and methods thereof
US8216256Feb 26, 2009Jul 10, 2012Evalve, Inc.Detachment mechanism for implantable fixation devices
US8221445Sep 24, 2004Jul 17, 2012Atritech, Inc.Barrier device for ostium of left atrial appendage
US8221451Sep 28, 2009Jul 17, 2012Curaseal Inc.Inflatable device for enteric fistula treatment
US8246671Aug 25, 2008Aug 21, 2012Cardiokinetix, Inc.Retrievable cardiac devices
US8252008Nov 29, 2010Aug 28, 2012Abbott LaboratoriesArticulating suturing device and method
US8257368Aug 9, 2007Sep 4, 2012Abbott LaboratoriesDevice for suturing intracardiac defects
US8257389May 4, 2005Sep 4, 2012W.L. Gore & Associates, Inc.Catching mechanisms for tubular septal occluder
US8257428May 12, 2003Sep 4, 2012Cardiokinetix, Inc.System for improving cardiac function
US8267947Jul 21, 2006Sep 18, 2012Abbott LaboratoriesVascular suturing device
US8277480Mar 20, 2006Oct 2, 2012W.L. Gore & Associates, Inc.Catch member for PFO occluder
US8277481Jun 26, 2006Oct 2, 2012Terumo Kabushiki KaishaTissue closure and tissue closing device
US8287563May 19, 2003Oct 16, 2012Atritech, Inc.Implant retrieval system
US8308752Aug 27, 2007Nov 13, 2012Cook Medical Technologies LlcBarrel occlusion device
US8308760Apr 20, 2005Nov 13, 2012W.L. Gore & Associates, Inc.Delivery systems and methods for PFO closure device with two anchors
US8313498Feb 7, 2011Nov 20, 2012Abbott LaboratoriesVascular suturing device
US8313505Feb 29, 2008Nov 20, 2012Aga Medical CorporationDevice for occluding vascular defects
US8323298Nov 19, 2010Dec 4, 2012Abbott LaboratoriesArticulating suturing device and method
US8323309 *May 19, 2003Dec 4, 2012Atritech, Inc.Adjustable left atrial appendage implant
US8323334Jan 28, 2009Dec 4, 2012Evalve, Inc.Methods and apparatus for cardiac valve repair
US8343174Sep 4, 2009Jan 1, 2013Evalve, Inc.Locking mechanisms for fixation devices and methods of engaging tissue
US8361088Oct 23, 2008Jan 29, 2013Abbott LaboratoriesDevice and method for suturing intracardiac defects
US8361110Apr 21, 2005Jan 29, 2013W.L. Gore & Associates, Inc.Heart-shaped PFO closure device
US8361138Jul 25, 2007Jan 29, 2013Aga Medical CorporationBraided occlusion device having repeating expanded volume segments separated by articulation segments
US8366741Sep 13, 2007Feb 5, 2013Cardia, Inc.Occlusion device with centering arm
US8372112Sep 7, 2004Feb 12, 2013St. Jude Medical, Cardiology Division, Inc.Closure devices, related delivery methods, and related methods of use
US8372113Mar 16, 2006Feb 12, 2013W.L. Gore & Associates, Inc.Curved arm intracardiac occluder
US8377094Sep 26, 2011Feb 19, 2013Curaseal Inc.Enteric fistula treatment devices
US8377114Apr 10, 2009Feb 19, 2013Cardiokinetix, Inc.Sealing and filling ventricular partitioning devices to improve cardiac function
US8382796Nov 25, 2009Feb 26, 2013St. Jude Medical, Cardiology Division, Inc.Closure devices, related delivery methods and related methods of use
US8388672Apr 10, 2009Mar 5, 2013Cardiokinetix, Inc.System for improving cardiac function by sealing a partitioning membrane within a ventricle
US8398537Jul 24, 2009Mar 19, 2013Cardiokinetix, Inc.Peripheral seal for a ventricular partitioning device
US8398670Jun 23, 2006Mar 19, 2013Aga Medical CorporationMulti-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body
US8398672May 14, 2010Mar 19, 2013Nitinol Devices And Components, Inc.Method for anchoring a medical device
US8398675Oct 25, 2002Mar 19, 2013Radi Medical Systems AbAbsorbable medical sealing device with retaining assembly having at least two loops
US8409239Nov 25, 2009Apr 2, 2013Nitinol Devices And Components, Inc.Medical device anchor and delivery system
US8409273Oct 30, 2007Apr 2, 2013Abbott Vascular IncMulti-catheter steerable guiding system and methods of use
US8419753Oct 7, 2008Apr 16, 2013Abbott LaboratoriesSuturing device with split arm and method of suturing tissue
US8430893Aug 23, 2012Apr 30, 2013Abbott LaboratoriesArticulating suturing device and method
US8430907Sep 28, 2012Apr 30, 2013W.L. Gore & Associates, Inc.Catch member for PFO occluder
US8449572Jul 13, 2012May 28, 2013Terumo Kabushiki KaishaTissue closure and tissue closing device
US8454633Aug 24, 2011Jun 4, 2013Aga Medical CorporationPercutaneous catheter directed intravascular occlusion devices
US8470028Jan 19, 2010Jun 25, 2013Evalve, Inc.Methods, systems and devices for cardiac valve repair
US8480694Jul 22, 2010Jul 9, 2013Covidien LpMethod and apparatus for anastomosis including an expandable anchor
US8480706Mar 31, 2006Jul 9, 2013W.L. Gore & Associates, Inc.Tubular patent foramen ovale (PFO) closure device with catch system
US8480707Jul 31, 2009Jul 9, 2013Cook Medical Technologies LlcClosure device and method for occluding a bodily passageway
US8480709Aug 21, 2012Jul 9, 2013W.L. Gore & Associates, Inc.Catching mechanisms for tubular septal occluder
US8491629Oct 17, 2011Jul 23, 2013Rex MedicalVascular hole closure delivery device
US8500761Dec 11, 2009Aug 6, 2013Abbott VascularFixation devices, systems and methods for engaging tissue
US8500790Jun 4, 2012Aug 6, 2013Cardiokinetix, Inc.Retrievable cardiac devices
US8500795Aug 25, 2008Aug 6, 2013Cardiokinetix, Inc.Retrievable devices for improving cardiac function
US8523897Sep 27, 2006Sep 3, 2013Atritech, Inc.Device for left atrial appendage occlusion
US8529430May 29, 2008Sep 10, 2013Cardiokinetix, Inc.Therapeutic methods and devices following myocardial infarction
US8529597May 19, 2010Sep 10, 2013Coherex Medical, Inc.Devices for reducing the size of an internal tissue opening
US8535343May 17, 2011Sep 17, 2013Atritech, Inc.Method for left atrial appendage occlusion
US8551135Mar 28, 2007Oct 8, 2013W.L. Gore & Associates, Inc.Screw catch mechanism for PFO occluder and method of use
US8568431Jan 16, 2011Oct 29, 2013W.L. Gore & Associates, Inc.Delivery/recovery system for septal occluder
US8568447Oct 15, 2012Oct 29, 2013W.L. Gore & Associates, Inc.Delivery systems and methods for PFO closure device with two anchors
US8574244Dec 19, 2007Nov 5, 2013Abbott LaboratoriesSystem for closing a puncture in a vessel wall
US8574264Sep 16, 2006Nov 5, 2013St. Jude Medical, Cardiology Division, Inc.Method for retrieving a closure device
US8579933 *Jun 2, 2006Nov 12, 2013Cordis CorporationPatent foramen ovale closure device
US8579936Jun 21, 2010Nov 12, 2013ProMed, Inc.Centering of delivery devices with respect to a septal defect
US8597309Sep 13, 2012Dec 3, 2013Abbott LaboratoriesSuturing device with split arm and method of suturing tissue
US8597324Dec 28, 2009Dec 3, 2013Rex Medical L.P.Vascular hole closure device
US8617205Jun 10, 2010Dec 31, 2013Cook Medical Technologies LlcClosure device
US8628543 *Feb 28, 2011Jan 14, 2014Boston Scientific Scimed, Inc.Method and apparatus for endoscopic repair of the lower esophageal sphincter
US8636765Apr 5, 2013Jan 28, 2014W.L. Gore & Associates, Inc.Catch member for PFO occluder
US8657873May 7, 2007Feb 25, 2014Cardiokinetix, Inc.System for improving cardiac function
US8663248Dec 12, 2008Mar 4, 2014Abbott LaboratoriesArticulating suturing device and method
US8663252Sep 1, 2010Mar 4, 2014Abbott Cardiovascular Systems, Inc.Suturing devices and methods
US8663273Oct 17, 2011Mar 4, 2014Atritech, Inc.Method of implanting an adjustable occlusion device
US8672827Jan 21, 2010Mar 18, 2014Cardiokinetix, Inc.Cardiac device and methods of use thereof
US8676349Sep 14, 2007Mar 18, 2014Cardiac Pacemakers, Inc.Mechanism for releasably engaging an implantable medical device for implantation
US8685055Sep 4, 2003Apr 1, 2014Atritech, Inc.Filter apparatus for ostium of left atrial appendage
US8694129Jan 12, 2010Apr 8, 2014Cardiac Pacemakers, Inc.Deployable sensor platform on the lead system of an implantable device
US8721665Feb 10, 2012May 13, 2014The Trustees Of Columbia University In The City Of New YorkMethod and apparatus for circulatory valve repair
US8734483Aug 27, 2007May 27, 2014Cook Medical Technologies LlcSpider PFO closure device
US8734505Sep 24, 2009May 27, 2014Evalve, Inc.Methods and apparatus for cardiac valve repair
US8740918Jun 9, 2011Jun 3, 2014Evalve, Inc.Surgical device for connecting soft tissue
US8740920May 22, 2013Jun 3, 2014Evalve, Inc.Fixation devices, systems and methods for engaging tissue
US8740934Mar 30, 2006Jun 3, 2014Rex Medical, L.P.Closure device for left atrial appendage
US8747453Feb 18, 2008Jun 10, 2014Aga Medical CorporationStent/stent graft for reinforcement of vascular abnormalities and associated method
US8747454May 7, 2007Jun 10, 2014Cardiokinetix, Inc.System for improving cardiac function
US8747483Nov 16, 2012Jun 10, 2014ProMed, Inc.Needle apparatus for closing septal defects and methods for using such apparatus
US8753362Sep 18, 2013Jun 17, 2014W.L. Gore & Associates, Inc.Double spiral patent foramen ovale closure clamp
US8758395Jul 19, 2005Jun 24, 2014Septrx, Inc.Embolic filtering method and apparatus
US8758401Sep 30, 2011Jun 24, 2014ProMed, Inc.Systems and methods for treating septal defects
US8758403Jun 28, 2011Jun 24, 2014W.L. Gore & Associates, Inc.PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US8764848Sep 26, 2005Jul 1, 2014W.L. Gore & Associates, Inc.Occluder device double securement system for delivery/recovery of such occluder device
US8777974Jun 21, 2007Jul 15, 2014Aga Medical CorporationMulti-layer braided structures for occluding vascular defects
US8777984Mar 12, 2013Jul 15, 2014Cordis CorporationPatent foramen ovale closure device
US8777985Jan 9, 2013Jul 15, 2014St. Jude Medical, Cardiology Division, Inc.Closure devices, related delivery methods and tools, and related methods of use
US8784448Sep 15, 2008Jul 22, 2014W.L. Gore & Associates, Inc.Patent foramen ovale (PFO) closure device with radial and circumferential support
US8790242Oct 26, 2010Jul 29, 2014Cardiokinetix, Inc.Ventricular volume reduction
US8795329Aug 15, 2010Aug 5, 2014W.L. Gore & Associates, Inc.Removable intracardiac RF device
US8801746May 4, 2004Aug 12, 2014Covidien LpSystem and method for delivering a left atrial appendage containment device
US8814947Mar 29, 2007Aug 26, 2014W.L. Gore & Associates, Inc.Deformable flap catch mechanism for occluder device
US8827892Aug 22, 2013Sep 9, 2014Cardiokinetix, Inc.Therapeutic methods and devices following myocardial infarction
US8828049Jan 21, 2010Sep 9, 2014W.L. Gore & Associates, Inc.Split ends closure device and methods of use
US8834519Nov 18, 2011Sep 16, 2014Artritech, Inc.Method and device for left atrial appendage occlusion
US8840655Aug 8, 2007Sep 23, 2014Coherex Medical, Inc.Systems and devices for reducing the size of an internal tissue opening
USRE40863 *Oct 22, 1993Jul 21, 2009Boston Scientific Scimed, Inc.Apparatus and method for sealing vascular punctures
EP0876793A2Jan 21, 1993Nov 11, 1998Regents Of The University Of MinnesotaSeptal Defect Closure Device
EP1222897A2Jan 11, 2002Jul 17, 2002Microvena CorporationSeptal defect occluder
EP1844717A2Oct 12, 1998Oct 17, 2007Aga Medical CorporationPercutaneous catheter directed constricting occlusion device
EP1923005A2Mar 11, 2005May 21, 2008Aga Medical CorporationMulti-Layer braided structures for occluding vascular defects
EP1955661A2Jan 11, 2002Aug 13, 2008ev3 Endovascular, Inc.Septal defect occluder
EP1980200A2Mar 12, 1996Oct 15, 2008Heartport, Inc.Method and apparatus for thoracoscopic intradcardiac procedures
EP2078498A1Apr 7, 2000Jul 15, 2009Evalve, Inc.Apparatus for cardiac valve repair
EP2135560A1 *Jun 2, 2006Dec 23, 2009Cordis CorporationPatent foramen ovale closure device
EP2158847A1Jul 25, 2001Mar 3, 2010ev3 Endovascular, Inc.Occluder delivery system
EP2223657A1Sep 23, 2004Sep 1, 2010Abbott LaboratoriesDevice for suturing intracardiac defects
EP2228020A1Mar 11, 2005Sep 15, 2010AGA Medical CorporationMulti-layer braided structures for occluding vascular defects
EP2263569A1Oct 12, 1998Dec 22, 2010Aga Medical CorporationPercutaneous catheter directed constricting occlusion device
EP2428169A1Sep 14, 2011Mar 14, 2012Evalve, Inc.Flexible actuator mandrel for tissue apposition systems
WO1992019162A2 *Apr 23, 1992Nov 12, 1992Arnold S SeidSurgical implantation device and related method of use
WO1993013712A1 *Jan 21, 1993Jul 22, 1993Univ MinnesotaSeptal defect closure device
WO1996032882A1Mar 12, 1996Oct 24, 1996Heartport IncMethod and apparatus for thoracoscopic intracardiac procedures
WO1999012478A1Sep 1, 1998Mar 18, 1999Aga Medical CorpPercutaneous catheter directed occlusion devices
WO1999039646A1Oct 12, 1998Aug 12, 1999Aga Medical CorpPercutaneous catheter directed constricting occlusion device
WO2003061481A1 *Jan 15, 2003Jul 31, 2003Cardia IncOcclusion device with non-thrombogenic properties
WO2004067092A2 *Jan 20, 2004Aug 12, 2004Cardia IncSeptal stabilization device
WO2005112792A2May 16, 2005Dec 1, 2005Evalve IncLocking mechanisms for fixation devices and methods of engaging tissue
WO2006047709A2Oct 25, 2005May 4, 2006Evalve IncFixation devices for variation in engagement of tissue
WO2006135747A2 *Jun 8, 2006Dec 21, 2006Cardiokinetix IncPeripheral seal for a ventricular partitioning device
Classifications
U.S. Classification606/215, 606/153, 128/899
International ClassificationA61F2/24, A61B17/00
Cooperative ClassificationA61B2017/00243, A61B2017/00592, A61B2017/00575, A61B17/0057, A61B2017/00623, A61B2017/00606
European ClassificationA61B17/00P
Legal Events
DateCodeEventDescription
Sep 5, 2001FPAYFee payment
Year of fee payment: 12
Apr 24, 1997FPAYFee payment
Year of fee payment: 8
May 11, 1993FPAYFee payment
Year of fee payment: 4