|Publication number||US5254130 A|
|Application number||US 07/867,649|
|Publication date||Oct 19, 1993|
|Filing date||Apr 13, 1992|
|Priority date||Apr 13, 1992|
|Also published as||CA2118006A1, CA2118006C, DE69316353D1, DE69316353T2, EP0636010A1, EP0636010B1, WO1993020760A1|
|Publication number||07867649, 867649, US 5254130 A, US 5254130A, US-A-5254130, US5254130 A, US5254130A|
|Inventors||Philippe Poncet, Karl van Dyk|
|Original Assignee||Raychem Corporation|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (12), Non-Patent Citations (1), Referenced by (312), Classifications (21), Legal Events (5)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This invention relates to surgical devices, particularly to remotely operated surgical devices for use in least invasive surgical (LIS) techniques.
LIS techniques are in contrast to open surgical techniques. They include operation through natural ducts within the body (endoscopy) and operation through one or more relatively small openings made by the surgeon in the patient's body (percutaneous techniques), for example laparoscopic surgery involving making small openings in the patient's abdominal wall, and arthroscopic surgery involving making small openings in a joint region. Advantages of LIS, compared to open surgery, are lower morbidity rates, shorter patient recovery times and lower costs of the procedure.
Surgical devices used in LIS are remotely operated. Typically devices are inserted into the patient's body, the operating head of the device is projected beyond the distal end of the housing, and this operating head is then activated by the surgeon from the proximal end of the device.
Simple, known LIS surgical devices use, for example, flexible steel wires which spring apart when extended from the distal end of a tube and which can be brought together again on withdrawal back into the tube. Examples of such devices are described, in U.S. Pat. Nos. 2,114,695, 2,137,710, 2,670,519, and 3,404,677.
Numerous LIS surgical devices incorporating a variety of special materials, including shape memory alloys are also known. U.S. Pat. No. 4,926,860 to Stice et al, issued 22 May 1990, for example, describes an arthroscopic procedure using a curved cannula and a normally straight shape memory alloy probe. The curved cannula facilitates access to parts of the joint, and bends the probe as it passes therethrough. However when the probe exits from the distal end of the cannula it adopts its normal straight configuration.
Also U.S. Pat No. 4,665,906 to Jervis discloses medical devices which make use of the pseudoelastic (SIM) properties of certain shape memory alloys. SIM pseudoelastic properties and their advantages are discussed in more detail later in this specification.
LIS devices incorporating elastic materials, including pseudoelastic shape memory alloys are also known, as described in U.S. Ser. No. 843,775 pending to the Applicant, filed Feb. 28, 1992. One embodiment described therein is an apparatus which enables passage of a ligature around a bone or other body member, or grasping of such a body member without requiring the surgical instrument to be swept over a wide angle of motion. The apparatus includes a cannula and a pseudo elastic member within the cannula. An example given is for the cannula to be straight and for the pseudo elastic member to adopt a curved configuration when extended from the cannula sufficient to grasp and manipulate a body structure. Another embodiment describes delivery of a needle to a surgical site through a curved arc by using a pseudo elastic needle. Other similar examples all involving the extension of pseudo elastic members from a housing to manipulate matter are described in U.S. Ser. No. 843,775. Other examples where the advantages of the pseudo elastic members in accessing difficult spaces within the patient's body would be evident to the man skilled in the art. The disclosure of U.S. Ser. No. 843,775 is incorporated herein by reference.
LIS surgical devices involving rotation of a knife are also known. For example, U.S. Pat. No. 4,723,545 to Nixon and Mombrimie, issued 9th Feb. 1988 describes a surgical instrument suited for arthroscopic surgery comprising a blade mounted in a tubular body portion so that it can project beyond the body portion and so that is can oscillate with respect to the body portion. This oscillation of the blade facilitates the cutting process, nothwithstanding the toughness or cut resistance of the tissue or the like which is to be repaired. Also U.S. Pat. No. 4203444 to Bonnell et al, issued on 20th May 1980 describes a surgical instrument for use in closed surgery of the knee, comprising an outer tube containing an inner tube. The inner tube is provided with shearing edges which form a blade. The inner tube can rotate within the outer tube at speeds in the range of 100-200 rpm, and a vacuum may be provided to withdraw the material sheared by the blade.
A problem experienced with the LIS and other surgical devices used in the past is in achieving movement in three dimensions to precisely access the desired surgical site, and to move the surgical instrument in the desired directions once it is at the desired surgical site.
U.S. Pat. No. 4882777 to Narula issued 21 Nov. 1989 provides some three dimensional character in the positioning of a catheter. This describes a catheter which is sufficiently resilient to deform to a linear configuration for insertion through a narrow tube, but which has a complex curvature that is not limited to a single plane. This skews the extreme distal end of the catheter relative to a straight portion and a first curved portion of the catheter, allowing automatic positioning of the distal end adjacent the desired internal location. However the automatic positioning is still to a desired predetermined position defined by the complex curvature of the catheter.
It is an object of the present invention to overcome the deficiencies of the prior art surgical devices, in particular the prior art LIS surgical devices.
It is a particular object of the present invention to provide a surgical device which allows another degree of freedom of movement to an operator of the surgical device, outside a single plane. In particular it is an object of the invention to provide a device in which the operator of the surgical device can deliver the head of the surgical device to a surgery site along a first path, which may be any direction of path but is typically a curved path in a single plane, and can then rotate the head of the device in another dimension, for example around the axis defined by the direction of the first path.
It is a further object of the present invention to provide a surgical device that is small in transverse dimensions, and is thus suitable for use in LIS techniques.
The present invention provides a surgical device comprising
(a) a tubular housing having a longitudinal bore extending therethrough,
(b) a first elongate member extending through the longitudinal bore of the housing, and having a proximal and a distal segment, where at least part of the distal segment comprises an elastic material (as hereinafter defined), and wherein the distal segment assumes a first shape when extended from the longitudinal bore, and a second shape when withdrawn into the bore,
(c) a second elongate member also having a proximal and a distal segment, the second elongate member extending substantially parallel to the first elongate member so that it is moved by the first elongate member, when the first elongate member changes from its first to its second shape and vice versa, the second elongate member being rotatable relative to, and substantially about, the axis of the first elongate member, and
(d) an operating head secured to the distal segment of the second elongate member so that it
(i) is moved with the second elongate member when the first elongate member changes from its first to its second shape and
(ii) can be rotated by the second elongate member substantially about the axis of the first elongate member.
FIGS. 1 and 2 are partly cut away, partly sectional and partly perspective views of first and second embodiments of surgical device according to the invention.
The present invention requires at least part of the distal segment of the first elongate member to comprise an elastic material.
Any elastic material may be used in some of the embodiments of this invention, but it is generally preferred to use a pseudoelastic material. Many different materials exhibit pseudoelasticity and can be used in any embodiment of this invention. It is preferred to use a pseudoelastic shape memory alloy.
The term "elastic material" is used herein to mean a material that has spring-like properties, that is, it is capable of being deformed by an applied stress and then springing back, or recovering, to or toward its original unstressed shape or configuration when the stress is removed. The elastic material is preferably highly elastic. The material can be polymeric or metallic, or a combination of both. The use of metals, such as shape memory alloys, is preferred. Shape memory alloys that exhibit pseudoelasticity, in particular superelasticity, are especially preferred. The elastic materials herein exhibit greater than 1% elastic deformation, more generally greater than 2% elastic deformation. Preferably, the elastic materials herein exhibit greater than 4% elastic deformation, more preferably greater than 6% elastic deformation.
Preferably, the elastic member is at least partially formed from a pseudoelastic material, such as a shape memory alloy that exhibits pseudoelasticity. Shape memory alloys which exhibit superelasticity (also referred to in the literature as non-linear pseudoelasticity), are especially preferred.
U.S. Pat. No. 4,935,068 to Duerig, which is commonly assigned with the present application and incorporated herein by reference, teaches the fundamental principles of shape memory alloys. Some alloys which are capable of transforming between martensitic and austenitic phases are able to exhibit a shape memory effect. The transformation between phases may be caused by a change in temperature. For example, a shape memory alloy in the martensitic phase will begin to transform to the austenitic phase when its temperature rises above AS and the transformation will be complete when the temperature rises above Af. The forward transformation will begin when the temperature drops below MS and will be complete when the temperature drops below Mf. The temperatures MS, Mf, AS , and Af define the thermal transformation hysteresis loop of the shape memory alloy.
Under certain conditions, shape memory alloys exhibit pseudoelasticity, which does not rely on temperature change in order to accomplish shape change. A pseudoelastic alloy is capable of being elastically deformed far beyond the elastic limits of conventional metals.
The property of pseudoelasticity of certain shape memory alloys, which preferably is used in the devices of this invention, is the subject of a paper entitled "An Engineer's Perspective of Pseudoelasticity", by T. W. Duerig and R. Zadno, published in Engineering Aspects of Shape Memory Alloys, page 380, T. W. Duerig, K. Melton, D. Stoeckel, and M. Wayman, editors, Butterworth Publishers, 1990 (proceedings of a conference entitled "Engineering Aspects of Shape Memory Alloys", held in Lansing, Mich. in August 1988). As discussed in the paper, the disclosure of which is incorporated herein by reference, certain alloys are capable of exhibiting pseudoelasticity of two types.
"Superelasticity" arises in appropriately treated alloys while they are in their austenitic phase at a temperature which is greater than AS and less than Md (AS is the temperature at which, when a shape memory alloy in its martensitic phase is heated, the transformation to the austenitic phase begins, and Md is the maximum temperature at which the transformation to the martensitic phase can be induced by the application of stress). Superelasticity can be achieved when the alloy is annealed at a temperature which is less than the temperature at which the alloy is fully recrystallized. Alternative methods of creating superelasticity in shape memory alloys, such as solution treating and aging, or alloying, are also discussed in "An Engineer's Perspective of Pseudoelasticity", referenced above. An article may be provided with a desired configuration by holding it in that configuration during annealing, or during solution treatment and aging. An article formed from an alloy which exhibits superelasticity can be deformed substantially reversibly by 11% or more. In contrast, "linear pseudoelasticity", is believed not to be accompanied by a phase change. It is exhibited by shape memory alloys which have been cold worked or irradiated to stabilize the martensite, but have not been annealed in the manner discussed above. An article formed from an alloy which exhibits linear pseudoelasticity can be deformed substantially reversibly by 4% or more. The treatment of shape memory alloys to enhance their pseudoelastic properties is also discussed in above-mentioned U.S. Pat. No. 4,935,068 to Duerig, incorporated herein by reference.
While the alloy that is used in the devices of this invention may exhibit either linear pseudoelasticity or superelasticity (which is sometimes referred to as non-linear pseudoelasticity), or pseudoelasticity of an intermediate type, it is generally preferred that it exhibit superelasticity because of the large amount of deformation that is available without the onset of plasticity. U.S. Pat. No. 4,665,906 to Jervis, which is commonly assigned with the present application and is incorporated herein by reference, teaches the use of pseudoelastic shape memory alloys in medical devices.
The pseudoelastic material will be selected according to the characteristics desired of the article. When a shape memory alloy is used, it is preferably a nickel titanium based alloy, which may include additional elements which might affect the yield strength that is available from the alloy or the temperature at which particular desired pseudoelastic characteristics are obtained. For example, the alloy may be a binary alloy consisting essentially of nickel and titanium, for example 50.8 atomic percent nickel and 49.2 atomic percent titanium, or it may include a quantity of a third element such as copper, cobalt, vanadium, chromium or iron. Alloys consisting essentially of nickel, titanium and vanadium, such as disclosed in U.S. Pat. No. 4,505,767, the disclosure of which is incorporated herein by reference, are preferred for some applications, particularly since they can also exhibit superelastic properties at or around body temperatures, and because they are stiffer and/or can store more elastic energy. Copper based alloys may also be used, for example alloys consisting essentially of copper, aluminum and nickel; copper, aluminum and zinc; and copper and zinc.
An article exhibiting superelasticity can be substantially reversibly deformed, by as much as eleven percent or more. For example, a 1.00 meter length of superelastic wire may be stretched to 1.11 meters in length, wherein its alloy will undergo a phase change to at least a partially more martensitic phase known as stress-induced-martensite. Upon release of the stress, the wire will return substantially to its 1.00 meter length, and its alloy will, correspondingly, return at least substantially toward its more austenitic phase. By way of contrast, a similar wire of spring steel or other conventional metal may only be elastically stretched approximately one percent, or to 1.01 meter in length. Any further stretching of the conventional wire, if not resulting in actual breakage of the wire, will result in a non-elastic (plastic) transformation such that, upon relief of the stress, the wire will not return to its original length. Linear pseudoelastic and superelastic materials may also be bent, twisted, and compressed, rather than stretched, to a far greater degree than conventional metals.
It is believed that the superelastic property is achieved by phase transformation within the alloy, rather than by the dislocation movements which occur during the plastic deformation of ordinary metals. A superelastic material may be deformed and released thousands of times, without being subject to breakage due to the metal fatigue which limits the number of deformation cycles which an ordinary metal may undergo without failure.
Shape memory alloys have a special feature which is beneficial for certain of the embodiments of this invention. As a superelastic shape memory alloy is increasingly deformed from its unconstrained shape, some of its austenitic phase changes into stress-induced-martensite. The stress/strain curve presents a plateau during this phase change. This means that while the alloy undergoes this phase change, it can deform greatly with only minimal increases in loading. Therefore, elements comprising superelastic shape memory alloys have a built-in safety feature. These elements can be designed (using appropriately treated alloys and appropriate dimensions) such that when they are loaded beyond a certain amount, the elements will tend to deform with a concomitant austenite to stress-induced-martensite phase change, instead of merely presenting a greater resistance or force with limited deformation to the load, which is seen with conventional metals.
Just as the stress strain curves of shape memory alloys present a plateau upon loading, they also present a plateau in the stress strain curve upon unloading. Unloading occurs when an element made of superelastic shape memory alloy is permitted to revert from a significantly deformed shape toward its original unstressed shape. Because of the plateau, such an element can maintain an almost constant force during much of the unloading cycle until just before it is completely unloaded.
In one embodiment of the invention therefore the elastic material is selected to have an As lower than ambient temperature, so that when the distal segment of the first elongate member is extended from the bore of the tubular housing it adopts its original (i.e. previous and predetermined) shape. For example the tubular housing may be straight, and the first member be constrained to a generally straight configuration therein, but adopt a curved configuration when extended from the end of the housing.
In addition, the surgical device of the present invention comprises a second elongate member that is rotatable relative to the first elongate member, and which carries an operating head at its distal end which can similarly be rotated by the second elongate member about the first elongate member.
The operating head may comprise for example a laparoscopic needle driver, scissors, forceps, dissectors, graspers, or the like, or a holding means for such instruments. The invention allows the operator to deliver the operating head along a predetermined path, and then allows an extra degree of freedom of movement of the operating head, by rotation. Thus the flexibility and opportunity of direction of movement of the operating head achieved by the combination of the initial elastic behavior of the first elongate member, and the rotation achievable by the second elongate member is greatly increased.
Any suitable arrangement whereby the second elongate member is movable by the first elongate member, and is additionally rotatable therearound is within the scope of the present invention. In one embodiment at least part of at least the distal segment of the second elongate member is tubular and surrounds at least part of the first elongate member. Preferably the surrounding tubular second member is flexible. This construction means that as the first member changes from its first to second shape, the second member will move with the first member to follow that shape change. Preferably the second elongate member is sufficiently flexible that it can be moved by the first member with little or no resistance from its own structure. As examples, at least part of at least the distal segment of the second member may comprise any of the following: a circumferentially corrugated tube, a spring, a fibrous braided tube, a flexible polymeric tube, or a polymeric braided tube. Where a circumferentially corrugated configuration is used this can provide the flexibility.
The proximal segment of the second elongate member is preferably continuous with its distal segment, and may take the same or a different form. In use the proximal segment may remain at all times within the housing, therefore flexibility may not be required or desired for the proximal segment. This is especially true if the housing is linear. Preferably the proximal segment of the second elongate member extends beyond the proximal end of the housing. This allows the operator of the surgical device to handle the proximal segment to rotate the second member around the first from the proximal end of the device. For example where the surgical device is used in an LIS technique it allows rotation of the operating head of the device to be effected by rotation by the operator of the second member, at the proximal end of the device, outside of the patient's body.
The distal end of the second member, which in use, enters into, or may enter into, contact with the internal parts of the patient's body may comprise a polymeric material. Suitable materials would be apparent to the man skilled in the art.
In a different embodiment of the invention at least part of at least the distal segment of the second elongate element extends within at least part of at least the distal segment of the first elongate element. In other words, the position of the first and second elongate members are interchanged compared to the above described embodiment. For example at least the distal segment of the first elongate element (which comprises an elastic material) may define a tube. It may be in the form of a tube, or it may, for example, comprise elongate bars and tie bars which together define the periphery of a tube. Provided the distal segment can behave elastically as defined, it can take any suitable form. The second elongate member used in combination with the tubular first elongate member may also be in the form of a tube, or may be in the form of a cable, for example of the type used in a speedometer or the like. This cable can pass through the first elongate member, and can act on the operating head remotely from the proximal end of the device. In this embodiment the proximal segment of the first elongate member is preferably also tubular and is preferably secured to, or integral with, the distal segment thereof so relative rotation therebetween is prevented. The distal segment comprises elastic material. The proximal segment may or may not comprise elastic material. For cost reasons it may not do.
The operating head of the surgical device may take any suitable form depending on the nature of the use of the device. For multi-functionability the head may comprise a clevis or the like, i.e. a holding means (for example in the case of a clevis, a U-shaped holding means) to which specific instruments can be secured, eg jaws of a clamp or forceps, a needle for suturing, blades of, for example, scissors or the like. Thus such instruments may be directly attached to the second elongate member of the device, or they may be secured in a holding means such as a clevis or the like, which is itself secured to the second elongate member.
Where the instrument at the operating head needs to be activated e.g. where it comprises mating jaws or mating blades of clamps, forceps or scissors, then elongate activating means may pass within, or along the outside of, the outer of the first and second elongate member.
At least the distal segment of the first elongate element preferably comprises a shape memory alloy, preferably a pseudoelastic, especially a superelastic alloy. In use, the first and second elongate members are preferably constrained at ambient temperature, within the housing in their stress induced martensitic state. When the device is inserted into the body, the first and second elongate members are then moved longitudinally relative to the tube so that the distal segments thereof project beyond the end of the housing. The distal segment of the first elongate member is then unstressed, and being above its As temperature reverts to its austenitic state, and hence to its original austenitic shape. As explained above very large shape changes can be achieved in this way. Typically a first pseudoelastic member deformed within a straight housing may adopt a curved configuration on exiting the housing. The second member (which as explained above preferably extends within the first member, or is itself tubular and surrounds the first member) follows the path of the first member, and is preferably flexible to enable it to do this. The second member can then or simultaneously be rotated about the first member to rotate the operating head.
According to the invention surgical devices having small transverse dimensions can be made that are nonetheless versatile in application, making them particularly suitable for LIS techniques. Preferably devices in which the housing (containing both first and second members) has a transverse dimension of less than 10 mm preferably less than 7 mm, especially about 5 mm are used. Preferably the housing is substantially cylindrical and the transverse dimension is its diameter.
Referring now to the drawings, these show, by way of example only, embodiments of the present invention.
Referring to FIG. 1, a first surgical device suitable for use in LIS technique according to the invention is designated generally by the reference numeral 1. It comprises a tubular generally straight housing 3, and first and second elongate members 5 and 7 respectively extending through the housing 3. For simplicity we shall term the first elongate member 5 the "bending member 5" and the second elongate member 7 the "rotating member 7". Both the bending member 5 and the rotating member 7 are shown deployed beyond the distal end of the surgical device. This is the position they would be deployed within the patient's body. Both can be retracted within the housing 3 by moving them longitudinally relative to the housing 3 in the direction indicated by arrow A. Typically they would be retracted within the housing for insertion into the patient's body.
The bending member 5 comprises a distal segment 5' and a proximal segment 5". The distal segment 5' comprises a tubular, pseudoelastic, preferably superelastic memory metal alloy. The proximal segment of the bending member 5 is also tubular. It is secured to the pseudoelastic segment, but does not itself exhibit memory behaviour. It is fixed relative to the housing 3 so it cannot be rotated relative to housing 3. The distal segment 5' of the bending member 5 can be deformed into a straight configuration by the action of the operator withdrawing it within housing 3 in the direction of arrow B in the Figure. When deployed outside the housing (as shown) by the operator moving it in the direction opposite to direction B it automatically adopts its previous "remembered" configuration, in this case a curved configuration as shown. Thus bending in a single plane (the plane of the paper), as depicted in FIG. 1 by arrow C is achieved by this bending member 5.
The second elongate member or rotating member 7 also comprises a distal segment 7' and a proximal segment 7" as shown. Both segments 7' and 7" are tubular and polymeric and surround corresponding segments 5' and 5" of the bending member. Segment 7' is circumferentially corrugated to render it flexible so that is easily bent with the bending segment 5' when deployed outside the housing 3. The proximal segment 7" is not corrugated since it does not need to bend. It is fixed to the corrugated distal segment 7' at point 9. The proximal segment 7" projects beyond the housing 3, and this projecting portion (designated 7'") can be rotated by the operator (outside the patient's body), causing simultaneous rotation of the corrugated distal segment 7'. The direction of rotation is depicted by the arrow C in FIG. 1. It is about the axis of bending member 5. The rotating member 7 is not fixed relative to bending member 5, and therefore can rotate around member 5.
The operating head of the surgical device is a holding means in the form of a clevis 11. In the U-bend of the clevis 11 clamping jaws 13 are pivoted.
The clevis 11 is secured to the corrugated segment 7' of the rotating member 7, so that when the projecting proximal segment 7'" of that member is rotated by the operator outside the housing and the patient, the torque is transmitted by the segment 7" and by the corrugated segment 7' to the clevis 11, so that rotation of the clevis 11 occurs around its own axis and around the bending member 5'. Transmission of the rotating torque to the clevis occurs in this way, by the corrugated segment 7', regardless of whether the bending and rotating members 5 and 7 are deployed fully, partly or not at all from the housing, ie regardless of whether the members 5 and 7 are straight or curved.
During an operation, the clevis can therefore be steered into the correct position by action of the first bending member 5 and then rotated by the operator by the rotating member 7, giving an extra degree of freedom for the operator of the instrument, ie three dimensional control is achieved.
The device 1 is also provided with an activating shaft 15 passing through the device which can activate the jaws 13. Any known mechanical linkage can be used to effect this activation.
The housing 3 may be any suitable dimension. It is preferably cylindrical with a diameter less than 5 mm.
FIG. 2 shows an alternative form of surgical device. Like parts to FIG. 1 are given identical reference numbers to FIG. 1. In this case the first elongate member 17 is referred to as the bending member 17. This is in the form of a tube surrounding the second elongate member, which is referred to as the rotating member 19. The rotating member 19 is in the form of a cable extending through the bending member 17. As in FIG. 1 the bending member 17 comprises a distal portion (designed 17') and a proximal portion (designed 17"). The distal portion 17' comprises a superelastic memory metal alloy that changes its shape from a stressed straight shape to an unstressed curved shape when deployed from the constraining housing 3. The rotating member 19 is in this case an integral cable extending through both sections 17' and 17" of the bending member. The rotating cable 19 is fixed to the clevis 11 (this fixture cannot be seen in FIG. 2 since it is hidden by the clevis 11.). Therefore it can cause the clevis 11 to rotate about its own axis, and also (as in FIG. 1) to rotate relative to the bending member 17. Thus, for example, with reference to FIG. 2 the clevis 11 can be made to slide circumferentially over the surface of bending member 17. It is not fixed thereto at the part 21 referenced in the drawings.
The rotating cable 19 can also serve as the activating cable to activate jaws 13, ie it can perform the function of both rotating member 7 and activating cable 15 of the embodiment of FIG. 1.
The embodiment of FIG. 2, like that of FIG. 1, therefore allows movement of the device in the plane of the paper (ie as indicated by arrow B) and in a perpendicular plane (as indicated by arrow C).
While the present invention has been shown and described with reference to preferred embodiments thereof it will be understood, by those skilled in the art, that the suggested variations and other changes in the form and detail of the devices may be made without departing from the scope and spirit of the invention.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2114695 *||Mar 5, 1937||Apr 19, 1938||Alfred W Anderson||Forceps|
|US2137710 *||Dec 13, 1937||Nov 22, 1938||Alfred W Anderson||Forceps|
|US2670519 *||Oct 24, 1951||Mar 2, 1954||Charles F Recklitis||Drainage tube with clot extractor|
|US3404677 *||Jul 8, 1965||Oct 8, 1968||Henry A. Springer||Biopsy and tissue removing device|
|US3958576 *||Nov 12, 1974||May 25, 1976||Olympus Optical Co., Ltd.||Surgical instrument for clipping any affected portion of a body cavity|
|US4200111 *||Sep 21, 1978||Apr 29, 1980||Harris Arthur M||Specimen removal instrument|
|US4203444 *||Nov 7, 1977||May 20, 1980||Dyonics, Inc.||Surgical instrument suitable for closed surgery such as of the knee|
|US4665906 *||May 21, 1986||May 19, 1987||Raychem Corporation||Medical devices incorporating sim alloy elements|
|US4723545 *||Feb 3, 1986||Feb 9, 1988||Graduate Hospital Foundation Research Corporation||Power assisted arthroscopic surgical device|
|US4882777 *||Apr 17, 1987||Nov 21, 1989||Narula Onkar S||Catheter|
|US4926860 *||Feb 5, 1988||May 22, 1990||Flexmedics Corporation||ARthroscopic instrumentation and method|
|US4945920 *||Oct 25, 1988||Aug 7, 1990||Cordis Corporation||Torqueable and formable biopsy forceps|
|1||*||U.S. Specification (Ser. No. 07/843,775, dated Feb. 28, 1992, Inventors Middleman et al).|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US5403342 *||Jun 21, 1993||Apr 4, 1995||United States Surgical Corporation||Articulating endoscopic surgical apparatus|
|US5411481 *||Oct 27, 1992||May 2, 1995||American Cyanamid Co.||Surgical purse string suturing instrument and method|
|US5413107 *||Feb 16, 1994||May 9, 1995||Tetrad Corporation||Ultrasonic probe having articulated structure and rotatable transducer head|
|US5417203 *||Apr 23, 1992||May 23, 1995||United States Surgical Corporation||Articulating endoscopic surgical apparatus|
|US5423854 *||Jul 30, 1993||Jun 13, 1995||Martin; Alain||Coelioscopic angulation forceps|
|US5425737 *||Jul 9, 1993||Jun 20, 1995||American Cyanamid Co.||Surgical purse string suturing instrument and method|
|US5439478 *||Jan 5, 1994||Aug 8, 1995||Symbiosis Corporation||Steerable flexible microsurgical instrument with rotatable clevis|
|US5445140 *||Jun 7, 1993||Aug 29, 1995||United States Surgical Corporation||Endoscopic surgical device|
|US5501654 *||Aug 16, 1994||Mar 26, 1996||Ethicon, Inc.||Endoscopic instrument having articulating element|
|US5562699 *||Mar 30, 1995||Oct 8, 1996||Richard Wolf Gmbh||Forceps|
|US5564615||Oct 31, 1995||Oct 15, 1996||Ethicon, Inc.||Surgical instrument|
|US5577654||May 23, 1996||Nov 26, 1996||Ethicon Endo-Surgery, Inc.||Surgical instrument|
|US5588580||May 23, 1996||Dec 31, 1996||Ethicon Endo-Surgery, Inc.||Surgical instrument|
|US5588581||May 23, 1996||Dec 31, 1996||Ethicon Endo-Surgery, Inc.||Surgical instrument|
|US5601224||Jun 10, 1994||Feb 11, 1997||Ethicon, Inc.||Surgical instrument|
|US5601582 *||Nov 16, 1994||Feb 11, 1997||Wilson-Cook Medical Inc.||Cutting catheter|
|US5607435 *||May 23, 1994||Mar 4, 1997||Memory Medical Systems, Inc.||Instrument for endoscopic-type procedures|
|US5620415 *||Sep 23, 1994||Apr 15, 1997||Smith & Dyonics, Inc.||Surgical instrument|
|US5624379 *||Oct 13, 1995||Apr 29, 1997||G. I. Medical Technologies, Inc.||Endoscopic probe with discrete rotatable tip|
|US5624508 *||May 2, 1995||Apr 29, 1997||Flomenblit; Josef||Manufacture of a two-way shape memory alloy and device|
|US5626587||May 18, 1995||May 6, 1997||Ethicon Endo-Surgery, Inc.||Method for operating a surgical instrument|
|US5634584||May 23, 1996||Jun 3, 1997||Ethicon Endo-Surgery, Inc.||Surgical instrument|
|US5643294 *||Mar 28, 1996||Jul 1, 1997||United States Surgical Corporation||Surgical apparatus having an increased range of operability|
|US5645564 *||May 22, 1995||Jul 8, 1997||Regents Of The University Of California||Microfabricated therapeutic actuator mechanisms|
|US5649938 *||May 1, 1995||Jul 22, 1997||American Cyanamid Co.||Surgical purse string suturing instrument and method|
|US5649955 *||Mar 17, 1995||Jul 22, 1997||Terumo Kabushiki Kaisha||Surgical instrument|
|US5662662||Sep 16, 1996||Sep 2, 1997||Ethicon Endo-Surgery, Inc.||Surgical instrument and method|
|US5676678 *||Jun 1, 1994||Oct 14, 1997||Schad; Gerhard||Surgical instrument with releasable jaw holder|
|US5697949 *||May 18, 1995||Dec 16, 1997||Symbiosis Corporation||Small diameter endoscopic instruments|
|US5716327 *||Jun 25, 1996||Feb 10, 1998||Origin Medsystems, Inc.||Body wall retraction system for wide cavity retraction|
|US5779727 *||Feb 18, 1997||Jul 14, 1998||Orejola; Wilmo C.||Hydraulically operated surgical scissors|
|US5782834 *||Feb 14, 1997||Jul 21, 1998||Smith & Nephew, Inc.||Surgical instrument|
|US5788710 *||Apr 30, 1996||Aug 4, 1998||Boston Scientific Corporation||Calculus removal|
|US5792165 *||Jun 6, 1995||Aug 11, 1998||Charles H. Klieman||Endoscopic instrument with detachable end effector|
|US5810876 *||Oct 3, 1995||Sep 22, 1998||Akos Biomedical, Inc.||Flexible forceps device|
|US5817119 *||Jun 25, 1996||Oct 6, 1998||Charles H. Klieman||Surgical instrument for endoscopic and general surgery|
|US5827323 *||Oct 4, 1996||Oct 27, 1998||Charles H. Klieman||Surgical instrument for endoscopic and general surgery|
|US5843098 *||Dec 10, 1996||Dec 1, 1998||American Cyanamid Co.||Surgical purse string suturing instrument and method|
|US5849022 *||Aug 6, 1997||Dec 15, 1998||Olympus Optical Co., Ltd.||Medical instrument for use in combination with endoscopes|
|US5876416 *||Sep 5, 1997||Mar 2, 1999||Hill; Frank C.||Surgical knife|
|US5882444 *||Apr 24, 1997||Mar 16, 1999||Litana Ltd.||Manufacture of two-way shape memory devices|
|US5895361 *||Feb 14, 1997||Apr 20, 1999||Symbiosis Corporation||Esophageal biopsy jaw assembly and endoscopic instrument incorporating the same|
|US5908381 *||Apr 30, 1997||Jun 1, 1999||C. R. Bard Inc.||Directional surgical device for use with endoscope, gastroscope, colonoscope or the like|
|US5931832 *||Jul 20, 1995||Aug 3, 1999||Sri International||Methods for positioning a surgical instrument about a remote spherical center of rotation|
|US5941249 *||Nov 25, 1996||Aug 24, 1999||Maynard; Ronald S.||Distributed activator for a two-dimensional shape memory alloy|
|US5951575 *||Mar 1, 1996||Sep 14, 1999||Heartport, Inc.||Apparatus and methods for rotationally deploying needles|
|US5957932 *||May 4, 1998||Sep 28, 1999||Boston Scientific Corporation||Calculus removal|
|US5967997 *||Apr 30, 1998||Oct 19, 1999||Symbiosis Corporation||Endoscopic surgical instrument with deflectable and rotatable distal end|
|US5976122 *||Feb 25, 1998||Nov 2, 1999||Integrated Surgical Systems, Inc.||Articulated surgical instrument for performing minimally invasive surgery with enhanced dexterity and sensitivity|
|US6072154 *||Dec 31, 1996||Jun 6, 2000||Medtronic, Inc.||Selectively activated shape memory device|
|US6099483 *||May 10, 1996||Aug 8, 2000||Symbiosis Corporation||Jaw assembly for an endoscopic instrument|
|US6133547 *||Sep 5, 1996||Oct 17, 2000||Medtronic, Inc.||Distributed activator for a two-dimensional shape memory alloy|
|US6139563 *||Sep 25, 1997||Oct 31, 2000||Allegiance Corporation||Surgical device with malleable shaft|
|US6169269 *||Aug 11, 1999||Jan 2, 2001||Medtronic Inc.||Selectively activated shape memory device|
|US6190399||May 10, 1996||Feb 20, 2001||Scimed Life Systems, Inc.||Super-elastic flexible jaw assembly|
|US6210424||Mar 5, 1998||Apr 3, 2001||Dicamed Ab||Surgical device|
|US6213940||Sep 2, 1999||Apr 10, 2001||United States Surgical Corporation||Surgical retractor including coil spring suture mount|
|US6235026||Aug 6, 1999||May 22, 2001||Scimed Life Systems, Inc.||Polypectomy snare instrument|
|US6269819||Jun 25, 1998||Aug 7, 2001||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US6278084||Apr 12, 2000||Aug 21, 2001||Medtronic, Inc.||Method of making a distributed activator for a two-dimensional shape memory alloy|
|US6319262||Jun 24, 1999||Nov 20, 2001||Boston Scientific Corporation||Calculus removal|
|US6323459||Apr 18, 2000||Nov 27, 2001||Medtronic, Inc.||Selectively activated shape memory device|
|US6371952||Jun 28, 1999||Apr 16, 2002||Intuitive Surgical, Inc.||Articulated surgical instrument for performing minimally invasive surgery with enhanced dexterity and sensitivity|
|US6517539||Nov 20, 2000||Feb 11, 2003||Scimed Life Systems, Inc.||Polypectomy snare having ability to actuate through tortuous path|
|US6537205||Nov 20, 2000||Mar 25, 2003||Scimed Life Systems, Inc.||Endoscopic instrument system having reduced backlash control wire action|
|US6537212||Feb 7, 2001||Mar 25, 2003||United States Surgical Corporation||Surgical retractor|
|US6546935||Dec 22, 2000||Apr 15, 2003||Atricure, Inc.||Method for transmural ablation|
|US6565508||Jul 13, 2001||May 20, 2003||United States Surgical Corporation||Surgical instrument|
|US6629534||Apr 7, 2000||Oct 7, 2003||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US6733445 *||May 22, 2002||May 11, 2004||United States Surgical Corporation||Surgical retractor|
|US6752813||Jun 27, 2001||Jun 22, 2004||Evalve, Inc.||Methods and devices for capturing and fixing leaflets in valve repair|
|US6761717||May 24, 2002||Jul 13, 2004||Scimed Life Systems, Inc.||Multifilar flexible rotary shaft and medical instruments incorporating the same|
|US6770083||Jul 24, 2002||Aug 3, 2004||Evalve, Inc.||Surgical device for connecting soft tissue|
|US6780175||Sep 17, 1998||Aug 24, 2004||Memory Medical Systems, Inc.||Medical instrument with slotted memory metal tube|
|US6840900||Dec 4, 2002||Jan 11, 2005||Scimed Life Systems, Inc.||Endoscopic instrument system having reduced backlash control wire action|
|US6889694||Dec 13, 2001||May 10, 2005||Atricure Inc.||Transmural ablation device|
|US6896673||Dec 23, 2002||May 24, 2005||Atricure, Inc.||Method for transmural ablation|
|US6899710||Dec 13, 2001||May 31, 2005||Atricure Inc.||Combination ablation and visualization apparatus for ablating cardiac tissue|
|US6899718||Apr 23, 2004||May 31, 2005||Heartport, Inc.||Devices and methods for performing avascular anastomosis|
|US6905498||May 31, 2002||Jun 14, 2005||Atricure Inc.||Transmural ablation device with EKG sensor and pacing electrode|
|US6913613 *||Jan 15, 2003||Jul 5, 2005||Tuebingen Scientific Surgical Products Ohg||Surgical instrument for minimally invasive surgical interventions|
|US6923806||Dec 12, 2001||Aug 2, 2005||Atricure Inc.||Transmural ablation device with spring loaded jaws|
|US6932811||Oct 26, 2001||Aug 23, 2005||Atricure, Inc.||Transmural ablation device with integral EKG sensor|
|US6962596||Mar 14, 2003||Nov 8, 2005||Bolduc Lee R||System for performing vascular anastomoses|
|US6972017||Jan 16, 2003||Dec 6, 2005||Scimed Life Systems, Inc.||Polypectomy snare having ability to actuate through tortuous path|
|US6974454||Dec 12, 2001||Dec 13, 2005||Atricure, Inc.||Transmural ablation device with thermocouple for measuring tissue temperature|
|US6984233||Aug 27, 2004||Jan 10, 2006||Atricure, Inc.||Transmural ablation device with parallel electrodes|
|US6984238||Apr 23, 2004||Jan 10, 2006||Gifford Iii Hanson S||Devices and methods for performing avascular anastomosis|
|US6991627||Feb 15, 2002||Jan 31, 2006||Intuitive Surgical Inc.||Articulated surgical instrument for performing minimally invasive surgery with enhanced dexterity and sensitivity|
|US6999852||Oct 26, 2004||Feb 14, 2006||Sri International||Flexible robotic surgery system and method|
|US7001415||Dec 12, 2001||Feb 21, 2006||Atricure, Inc.||Transmural ablation device|
|US7025775||May 15, 2003||Apr 11, 2006||Applied Medical Resources Corporation||Surgical instrument with removable shaft apparatus and method|
|US7033315||Oct 21, 2004||Apr 25, 2006||Scimed Life Systems, Inc.||Endoscope and endoscopic instrument system having reduced backlash when moving the endoscopic instrument within a working channel of the endoscope|
|US7037321||Aug 23, 2004||May 2, 2006||Memory Medical Systems, Inc.||Medical device with slotted memory metal tube|
|US7052495||May 14, 2001||May 30, 2006||Scimed Life Systems, Inc.||Polypectomy snare instrument|
|US7056326||Jun 2, 2004||Jun 6, 2006||Heartport, Inc.||System for performing vascular anastomoses|
|US7087066||Mar 3, 2004||Aug 8, 2006||Bolduc Lee R||Surgical clips and methods for tissue approximation|
|US7105002||Jan 19, 2001||Sep 12, 2006||Ethicon, Inc.||Anastomosis device and method|
|US7112211||Jan 9, 2003||Sep 26, 2006||Heartport, Inc.||Devices and methods for performing avascular anastomosis|
|US7113831||Dec 12, 2001||Sep 26, 2006||Atricure, Inc.||Transmural ablation device|
|US7122044||Apr 28, 2004||Oct 17, 2006||Heartport, Inc.||Surgical stapling instrument and method thereof|
|US7137949||Mar 26, 2003||Nov 21, 2006||United States Surgical Corporation||Surgical instrument|
|US7226467||May 19, 2003||Jun 5, 2007||Evalve, Inc.||Fixation device delivery catheter, systems and methods of use|
|US7276067||May 27, 2004||Oct 2, 2007||Boston Scientific Scimed, Inc.||Multifilar flexible rotary shaft and medical instruments incorporating the same|
|US7288097||Jun 24, 2004||Oct 30, 2007||Evalve, Inc.||Surgical device for connecting soft tissue|
|US7291161||Oct 2, 2002||Nov 6, 2007||Atricure, Inc.||Articulated clamping member|
|US7294104||Aug 26, 2003||Nov 13, 2007||United States Surgical Corporation||Surgical instrument holder|
|US7316681||Oct 4, 2005||Jan 8, 2008||Intuitive Surgical, Inc|
|US7341564||Apr 24, 2002||Mar 11, 2008||Boston Scientific Scimed, Inc.||Biopsy forceps device with transparent outer sheath|
|US7393353||Aug 18, 2004||Jul 1, 2008||Atricure, Inc.||Transmural ablation device with temperature sensor|
|US7410494 *||Jun 21, 2004||Aug 12, 2008||International And Surgical Innovations, Llc||Device for grasping and/or severing|
|US7464712||Apr 28, 2004||Dec 16, 2008||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US7470272||Jun 30, 2004||Dec 30, 2008||Medtronic, Inc.||Device and method for ablating tissue|
|US7487780||Aug 27, 2004||Feb 10, 2009||Atricure, Inc.||Sub-xyphoid method for ablating cardiac tissue|
|US7507235||May 28, 2002||Mar 24, 2009||Medtronic, Inc.||Method and system for organ positioning and stabilization|
|US7509959||Jun 30, 2004||Mar 31, 2009||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US7530980||Apr 13, 2005||May 12, 2009||Atricure, Inc||Bipolar transmural ablation method and apparatus|
|US7543589||Feb 15, 2007||Jun 9, 2009||Atricure, Inc.||Method for ablating cardiac tissue|
|US7553275||Aug 25, 2005||Jun 30, 2009||Surgical Solutions Llc||Medical device with articulating shaft|
|US7563267||May 19, 2003||Jul 21, 2009||Evalve, Inc.||Fixation device and methods for engaging tissue|
|US7563273||Jul 21, 2009||Evalve, Inc.||Methods and devices for capturing and fixing leaflets in valve repair|
|US7566334||Jun 2, 2005||Jul 28, 2009||Medtronic, Inc.||Ablation device with jaws|
|US7604646||May 16, 2005||Oct 20, 2009||Evalve, Inc.||Locking mechanisms for fixation devices and methods of engaging tissue|
|US7608083||Oct 27, 2009||Hansen Medical, Inc.||Robotically controlled medical instrument with a flexible section|
|US7608091||Jul 3, 2003||Oct 27, 2009||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US7635329||Sep 27, 2005||Dec 22, 2009||Evalve, Inc.||Methods and devices for tissue grasping and assessment|
|US7641667 *||Jan 5, 2010||Smith & Nephew, Inc.||Tissue cutting instrument|
|US7651510||Jan 12, 2001||Jan 26, 2010||Heartport, Inc.||System for performing vascular anastomoses|
|US7655015||Feb 2, 2010||Evalve, Inc.||Fixation devices, systems and methods for engaging tissue|
|US7666204||Feb 23, 2010||Evalve, Inc.||Multi-catheter steerable guiding system and methods of use|
|US7670284||Jun 8, 2007||Mar 2, 2010||Surgical Solutions Llc||Medical device with articulating shaft|
|US7678111||Mar 16, 2010||Medtronic, Inc.||Device and method for ablating tissue|
|US7682319||Mar 23, 2010||Evalve, Inc.||Steerable access sheath and methods of use|
|US7682369||Feb 14, 2006||Mar 23, 2010||Evalve, Inc.||Surgical device for connecting soft tissue|
|US7686826 *||Mar 30, 2010||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US7699835||Nov 17, 2003||Apr 20, 2010||Hansen Medical, Inc.||Robotically controlled surgical instruments|
|US7704269||Aug 5, 2003||Apr 27, 2010||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US7708758 *||Nov 28, 2006||May 4, 2010||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US7713190||Jun 14, 2007||May 11, 2010||Hansen Medical, Inc.||Flexible instrument|
|US7736388||Jan 16, 2007||Jun 15, 2010||Evalve, Inc.||Fixation devices, systems and methods for engaging tissue|
|US7740623||Jun 23, 2005||Jun 22, 2010||Medtronic, Inc.||Devices and methods for interstitial injection of biologic agents into tissue|
|US7744530||Jun 29, 2010||Tyco Healthcare Group Lp||Surgical instrument holder|
|US7744562||Oct 10, 2006||Jun 29, 2010||Medtronics, Inc.||Devices and methods for interstitial injection of biologic agents into tissue|
|US7744608||Jun 29, 2010||Hansen Medical, Inc.||Robotically controlled medical instrument|
|US7753923||Aug 25, 2004||Jul 13, 2010||Evalve, Inc.||Leaflet suturing|
|US7758596||Oct 15, 2002||Jul 20, 2010||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US7763041||Jul 27, 2010||Heartport, Inc.||Surgical clips and methods for tissue approximation|
|US7780651||Aug 24, 2010||Intuitive Surgical Operations, Inc.|
|US7811296||Oct 12, 2010||Evalve, Inc.||Fixation devices for variation in engagement of tissue|
|US7819884||Oct 26, 2010||Hansen Medical, Inc.||Robotically controlled medical instrument|
|US7824326||Nov 2, 2010||Boston Scientific Scimed, Inc.||Bioabsorbable casing for surgical sling assembly|
|US7854738||Dec 21, 2010||Hansen Medical, Inc.||Robotically controlled medical instrument|
|US7862580||Apr 11, 2007||Jan 4, 2011||Intuitive Surgical Operations, Inc.||Flexible wrist for surgical tool|
|US7875028||Jan 25, 2011||Medtronic, Inc.||Ablation device with jaws|
|US7890211||Feb 15, 2011||Intuitive Surgical Operations, Inc.||Master-slave manipulator system and apparatus|
|US7918783||Apr 5, 2011||Boston Scientific Scimed, Inc.||Endoscope working channel with multiple functionality|
|US7935129||May 3, 2011||Heartport, Inc.||Device for engaging tissue having a preexisting opening|
|US7938827||May 10, 2011||Evalva, Inc.||Cardiac valve leaflet attachment device and methods thereof|
|US7959557||Jun 13, 2007||Jun 14, 2011||Hansen Medical, Inc.||Robotic medical instrument system|
|US7967816||Jun 28, 2011||Medtronic, Inc.||Fluid-assisted electrosurgical instrument with shapeable electrode|
|US7972345||Jul 5, 2011||Olympus Corporation||Surgical instrument|
|US7981123||Feb 3, 2010||Jul 19, 2011||Evalve, Inc.||Surgical device for connecting soft tissue|
|US7981139||Jul 19, 2011||Evalve, Inc||Suture anchors and methods of use|
|US7998151||Aug 16, 2011||Evalve, Inc.||Leaflet suturing|
|US8029518||Oct 30, 2007||Oct 4, 2011||Evalve, Inc.||Methods and devices for capturing and fixing leaflets in valve repair|
|US8029531||Sep 27, 2006||Oct 4, 2011||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US8033983||Oct 11, 2011||Boston Scientific Scimed, Inc.||Medical implant|
|US8052592||Oct 7, 2009||Nov 8, 2011||Evalve, Inc.||Methods and devices for tissue grasping and assessment|
|US8052670||May 2, 2006||Nov 8, 2011||Evm Systems Llc||Medical device with slotted memory metal tube|
|US8057493||Dec 18, 2009||Nov 15, 2011||Evalve, Inc.||Fixation devices, systems and methods for engaging tissue|
|US8105350 *||Jan 31, 2012||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US8123703||Feb 3, 2010||Feb 28, 2012||Evalve, Inc.||Steerable access sheath and methods of use|
|US8133239||Sep 12, 2008||Mar 13, 2012||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US8137263||Aug 24, 2007||Mar 20, 2012||Karl Storz Endovision, Inc.||Articulating endoscope instrument|
|US8142347||Nov 20, 2003||Mar 27, 2012||Boston Scientific Scimed, Inc.||Self-orienting polypectomy snare device|
|US8162816||Apr 24, 2012||Boston Scientific Scimed, Inc.||System for implanting an implant and method thereof|
|US8162938||Apr 24, 2012||Boston Scientific Scimed, Inc.||Polypectomy snare having ability to actuate through tortuous path|
|US8162941||Apr 24, 2012||Medtronic, Inc.||Ablation device with jaws|
|US8187299||Oct 29, 2007||May 29, 2012||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US8216230||Apr 4, 2011||Jul 10, 2012||Evalve, Inc.||Cardiac valve leaflet attachment device and methods thereof|
|US8216256||Feb 26, 2009||Jul 10, 2012||Evalve, Inc.||Detachment mechanism for implantable fixation devices|
|US8221449||Feb 2, 2006||Jul 17, 2012||Applied Medical Resources Corporation||Surgical instrument with removable shaft apparatus and method|
|US8241280||Sep 12, 2007||Aug 14, 2012||Boston Scientific Scimed, Inc.||Multifilar flexible rotary shaft and medical instruments incorporating the same|
|US8273072||Sep 25, 2012||Medtronic, Inc.||Devices and methods for interstitial injection of biologic agents into tissue|
|US8323334||Jan 28, 2009||Dec 4, 2012||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US8337521||Nov 17, 2010||Dec 25, 2012||Intuitive Surgical Operations, Inc.||Flexible wrist for surgical tool|
|US8343141||Jul 9, 2010||Jan 1, 2013||Intuitive Surgical Operations, Inc.|
|US8343174||Jan 1, 2013||Evalve, Inc.||Locking mechanisms for fixation devices and methods of engaging tissue|
|US8377037||Feb 19, 2013||Evm Systems Llc||Medical device with slotted memory metal tube|
|US8398673||Feb 6, 2009||Mar 19, 2013||Surgical Innovations V.O.F.||Surgical instrument for grasping and cutting tissue|
|US8409273||Apr 2, 2013||Abbott Vascular Inc||Multi-catheter steerable guiding system and methods of use|
|US8419720||Feb 7, 2012||Apr 16, 2013||National Advanced Endoscopy Devices, Incorporated||Flexible laparoscopic device|
|US8459521 *||Jun 11, 2013||Covidien Lp||Powered surgical stapling device platform|
|US8470028||Jan 19, 2010||Jun 25, 2013||Evalve, Inc.||Methods, systems and devices for cardiac valve repair|
|US8500761||Dec 11, 2009||Aug 6, 2013||Abbott Vascular||Fixation devices, systems and methods for engaging tissue|
|US8506578||Apr 18, 2006||Aug 13, 2013||Boston Scientific Scimed, Inc.||Polypectomy snare instrument|
|US8579921||Jun 15, 2009||Nov 12, 2013||Covidien Lp||Spring-type suture securing device|
|US8585734||Aug 24, 2009||Nov 19, 2013||Board Of Regents Of University Of Nebraska||Ergonomic handle and articulating laparoscopic tool|
|US8617048||Mar 7, 2002||Dec 31, 2013||Boston Scientific Scimed, Inc.||System for implanting an implant and method thereof|
|US8617190||Mar 28, 2011||Dec 31, 2013||Heartport, Inc.||Device for engaging tissue having a preexisting opening|
|US8632453||Jul 15, 2008||Jan 21, 2014||Boston Scientific Scimed, Inc.||Spacer for sling delivery system|
|US8652028||Dec 2, 2004||Feb 18, 2014||Boston Scientific Scimed, Inc.||Endoscopic instrument system having reduced backlash control wire action|
|US8663089 *||Jun 21, 2004||Mar 4, 2014||Olympus Corporation||Treatment tool for endoscope|
|US8671950||Jun 13, 2007||Mar 18, 2014||Hansen Medical, Inc.||Robotic medical instrument system|
|US8672949||Mar 8, 2012||Mar 18, 2014||Boston Scientific Scimed, Inc.||Self-orienting polypectomy snare device|
|US8678998||Mar 3, 2006||Mar 25, 2014||Boston Scientific Scimed, Inc.||Endoscope and endoscopic instrument system having reduced backlash when moving the endoscopic instrument within a working channel of the endoscope|
|US8690908||Dec 3, 2012||Apr 8, 2014||Intuitive Surgical Operations, Inc.||Flexible wrist for surgical tool|
|US8709000||Dec 20, 2012||Apr 29, 2014||Intuitive Surgical Operations, Inc.|
|US8709021 *||Nov 5, 2007||Apr 29, 2014||Boston Scientific Scimed, Inc.||Suturing instrument|
|US8721665||Feb 10, 2012||May 13, 2014||The Trustees Of Columbia University In The City Of New York||Method and apparatus for circulatory valve repair|
|US8734505||Sep 24, 2009||May 27, 2014||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US8740918||Jun 9, 2011||Jun 3, 2014||Evalve, Inc.||Surgical device for connecting soft tissue|
|US8740920||May 22, 2013||Jun 3, 2014||Evalve, Inc.||Fixation devices, systems and methods for engaging tissue|
|US8790243||Feb 3, 2011||Jul 29, 2014||Intuitive Surgical Operations, Inc.||Flexible wrist for surgical tool|
|US8834352||Mar 1, 2011||Sep 16, 2014||Boston Scientific Scimed, Inc.||Endoscope working channel with multiple functionality|
|US8894668 *||Nov 19, 2008||Nov 25, 2014||Olympus Corporation||Surgical instrument|
|US8911428||Mar 7, 2012||Dec 16, 2014||Intuitive Surgical Operations, Inc.||Apparatus for pitch and yaw rotation|
|US9005112||Mar 29, 2012||Apr 14, 2015||Intuitive Surgical Operations, Inc.||Articulate and swapable endoscope for a surgical robot|
|US9005238||Aug 19, 2008||Apr 14, 2015||Covidien Lp||Endoscopic surgical devices|
|US9044246||Aug 24, 2011||Jun 2, 2015||Abbott Vascular Inc.||Methods and devices for capturing and fixing leaflets in valve repair|
|US9060858||May 28, 2013||Jun 23, 2015||Evalve, Inc.||Methods, systems and devices for cardiac valve repair|
|US9066744||Jul 5, 2013||Jun 30, 2015||Take5 Endotech||Surgical instrument for grasping and cutting tissue|
|US9095317||Jul 2, 2012||Aug 4, 2015||Intuitive Surgical Operations, Inc.||Flexible wrist for surgical tool|
|US9101373||Oct 15, 2012||Aug 11, 2015||Biomet Sports Medicine, Llc||Self-centering drill guide|
|US9211134||Apr 9, 2012||Dec 15, 2015||Carefusion 2200, Inc.||Wrist assembly for articulating laparoscopic surgical instruments|
|US9247929 *||May 7, 2012||Feb 2, 2016||Cook Medical Technologies Llc||Deflectable biopsy device|
|US9339286||Mar 1, 2010||May 17, 2016||Surgical Solutions Llc||Medical device with articulating shaft|
|US20010001826 *||Jan 12, 2001||May 24, 2001||Heartport, Inc.||System for performing vascular anastomoses|
|US20010001827 *||Jan 19, 2001||May 24, 2001||Chapman Troy J.||Anastomosis device and method|
|US20020103476 *||Feb 15, 2002||Aug 1, 2002||Intuitive Surgical, Inc.|
|US20020120316 *||Dec 12, 2001||Aug 29, 2002||Hooven Michael D.||Transmural ablation device with spring loaded jaws|
|US20020156487 *||Mar 7, 2002||Oct 24, 2002||Gellman Barry N.||System for implanting an implant and method thereof|
|US20030109898 *||Jan 15, 2003||Jun 12, 2003||Tuebingen Scientific Surgical Products Ohg||Surgical instrument for minimally invasive surgical interventions|
|US20030125731 *||Jan 16, 2003||Jul 3, 2003||Scimed Life Systems, Inc.||Polypectomy snare having ability to actuate through tortuous path|
|US20030130671 *||Nov 4, 2002||Jul 10, 2003||Duhaylongsod Francis G.||Anastomosis device and method|
|US20030135204 *||Nov 18, 2002||Jul 17, 2003||Endo Via Medical, Inc.||Robotically controlled medical instrument with a flexible section|
|US20030144681 *||Jan 29, 2002||Jul 31, 2003||Sample Philip B.||Tissue cutting instrument|
|US20030153933 *||Mar 14, 2003||Aug 14, 2003||Bolduc Lee R.||System for performing vascular anastomoses|
|US20040003819 *||Jul 3, 2003||Jan 8, 2004||Evalve, Inc.||Methods and apparatus for cardiac valve repair|
|US20040068274 *||Oct 2, 2002||Apr 8, 2004||Hooven Michael D.||Articulated clamping member|
|US20040087975 *||May 19, 2003||May 6, 2004||Evalve, Inc.||Fixation device delivery catheter, systems and methods of use|
|US20040092962 *||May 19, 2003||May 13, 2004||Evalve, Inc., A Delaware Corporation||Multi-catheter steerable guiding system and methods of use|
|US20040167547 *||Jul 3, 2003||Aug 26, 2004||Beane Richard M.||Surgical suture placement device|
|US20040172050 *||Mar 3, 2004||Sep 2, 2004||Bolduc Lee R.||Surgical clips and methods for tissue approximation|
|US20040220598 *||Jun 2, 2004||Nov 4, 2004||Bolduc Lee R.||System for performing vascular anastomoses|
|US20040225300 *||Mar 17, 2004||Nov 11, 2004||Evalve, Inc.||Methods and devices for capturing and fixing leaflets in valve repair|
|US20040230221 *||May 15, 2003||Nov 18, 2004||Applied Medical Resources Corporation||Surgical instrument with removable shaft apparatus and method|
|US20040236354 *||Jun 24, 2004||Nov 25, 2004||Evalve, Inc.||Surgical device for connecting soft tissue|
|US20050004432 *||Jun 21, 2004||Jan 6, 2005||Olympus Corporation||Treatment tool for endoscope|
|US20050021079 *||Jun 21, 2004||Jan 27, 2005||Menno Kalmann||Device for grasping and/or severing|
|US20050027245 *||Aug 23, 2004||Feb 3, 2005||Memory Medical Systems, Inc.||Medical instrument with slotted memory metal tube|
|US20050043582 *||Jun 16, 2004||Feb 24, 2005||Stokes Michael J.||Surgical instrument having an increased range of motion|
|US20050065658 *||Oct 26, 2004||Mar 24, 2005||Sri International||Flexible robotic surgery system and method|
|US20050154254 *||May 14, 2001||Jul 14, 2005||Smith Kevin W.||Polypectomy snare instrument|
|US20050283139 *||Jul 22, 2005||Dec 22, 2005||Olympus Corporation||Surgical therapeutic instrument, operation system, and anastomosing procedure method using the surgical therapeutic instrument|
|US20060020287 *||Jul 20, 2005||Jan 26, 2006||Woojin Lee||Surgical instrument|
|US20060030841 *||Oct 4, 2005||Feb 9, 2006||Madhani Akhil J|
|US20060089671 *||Oct 27, 2004||Apr 27, 2006||Evalve, Inc.||Fixation devices for variation in engagement of tissue|
|US20060129186 *||Feb 2, 2006||Jun 15, 2006||Applied Medical Resources Corporation||Surgical instrument with removable shaft apparatus and method|
|US20060135993 *||Feb 14, 2006||Jun 22, 2006||Evalve, Inc||Surgical device for connecting soft tissue|
|US20060206136 *||May 2, 2006||Sep 14, 2006||Memory Medical Systems, Inc.||Medical device with slotted memory metal tube|
|US20070060933 *||Jul 6, 2006||Mar 15, 2007||Meera Sankaran||Curette heads|
|US20070276430 *||Aug 16, 2006||Nov 29, 2007||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US20080015631 *||Sep 27, 2006||Jan 17, 2008||Woojin Lee||Surgical instrument|
|US20080021499 *||Nov 14, 2006||Jan 24, 2008||Olympus Corporation||Surgical instrument|
|US20080046000 *||Nov 28, 2006||Feb 21, 2008||Woojin Lee||Surgical instrument|
|US20080077159 *||Nov 27, 2007||Mar 27, 2008||Intuitive Surgical Inc.|
|US20080109015 *||Nov 5, 2007||May 8, 2008||Chu Michael S||Delivering Sutures|
|US20080177284 *||Jan 31, 2008||Jul 24, 2008||Hansen Medical, Inc.||Robotically controlled medical instrument|
|US20080242924 *||Feb 12, 2008||Oct 2, 2008||Hidefumi Akahane||Endoscopic treatment tool|
|US20080269790 *||Jul 3, 2008||Oct 30, 2008||Interventional & Surgical Innovations, Llc||Device for grasping and/or severing|
|US20080300461 *||May 31, 2007||Dec 4, 2008||Ethicon Endo-Surgery, Inc.||Endoscopic Device|
|US20090018572 *||Jul 3, 2008||Jan 15, 2009||Interventional & Surgical Innovations, Llc||Device for grasping and/or severing|
|US20090054733 *||Aug 24, 2007||Feb 26, 2009||Jacques Francois Bernard Marescaux||Articulating Endoscope Instrument|
|US20090076527 *||Nov 19, 2008||Mar 19, 2009||Olympus Corporation||Surgical instrument|
|US20090082788 *||Aug 27, 2008||Mar 26, 2009||Elmaraghy Amr||Suture management method and apparatus|
|US20090209991 *||Feb 6, 2009||Aug 20, 2009||Hinchliffe Peter W J||Surgical instrument for grasping and cutting tissue|
|US20090270857 *||Oct 29, 2009||Christian Steven C||Ablation Device with Jaws|
|US20090312605 *||Dec 17, 2009||Hallbeck M Susan||Ergonomic handle and articulating laparoscopic tool|
|US20090318938 *||Jun 15, 2009||Dec 24, 2009||Tyco Healthcare Group Lp||Spring-Type Suture Securing Device|
|US20100160736 *||Mar 1, 2010||Jun 24, 2010||Surgical Solutions Llc||Medical Device With Articulating Shaft|
|US20100280526 *||Apr 28, 2010||Nov 4, 2010||Arch Day Design, Llc||Medical Device With Articulating Shaft Mechanism|
|US20100292708 *||Jul 9, 2010||Nov 18, 2010||Intuitive Surgical Operations, Inc.||Articulated Surgical Instrument for Performing Minimally Invasive Surgery with Enhanced Dexterity and Sensitivity|
|US20100320254 *||Aug 26, 2010||Dec 23, 2010||Tyco Healthcare Group Lp||Powered surgical stapling device platform|
|US20110028991 *||Sep 29, 2010||Feb 3, 2011||Intuitive Surgical Operations, Inc.||Cardiac Tissue Ablation Instrument with Flexible Wrist|
|US20110213347 *||Sep 1, 2011||Cambridge Endoscopic Devices, Inc.||Surgical instrument|
|US20120220894 *||May 7, 2012||Aug 30, 2012||Melsheimer Jeffry S||Deflectable biopsy device|
|US20140236190 *||Apr 25, 2014||Aug 21, 2014||Boston Scientific Scimed, Inc.||Suturing instrument|
|US20140343588 *||Feb 27, 2013||Nov 20, 2014||Shoichi Nakamura||Medical instrument|
|USRE42625||Mar 15, 2006||Aug 16, 2011||The Regents Of The University Of California||Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas|
|USRE42662||Aug 30, 2011||The Regents Of The University Of California||Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas|
|USRE42756||Mar 15, 2006||Sep 27, 2011||The Regents Of The University Of California||Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas|
|CN102341049A *||Mar 3, 2010||Feb 1, 2012||伊顿株式会社||Surgical instrument|
|CN102341049B||Mar 3, 2010||Mar 12, 2014||伊顿株式会社||Surgical instrument|
|DE19518388A1 *||May 19, 1995||Nov 21, 1996||Wolf Gmbh Richard||Medizinisches Instrument mit einem abwinkelbaren distalen Endstück|
|EP0677275A2 *||Mar 17, 1995||Oct 18, 1995||Terumo Kabushiki Kaisha||Surgical instrument|
|EP1325709A1 *||Jan 4, 1995||Jul 9, 2003||Symbiosis Corporation||Flexible microsurgical instrument with rotatable clevis|
|EP1350475A1||May 10, 1996||Oct 8, 2003||Symbiosis Corporation||Jaw assembly for an endoscopic instrument|
|EP1491153A1 *||Jun 22, 2004||Dec 29, 2004||Olympus Corporation||Treatment tool for endoscope|
|EP1652483A1 *||Apr 29, 1998||May 3, 2006||CONMED Endoscopic Technologies, Inc.||Directional endoscopic surgical device|
|EP2282664A1 *||Jun 2, 2009||Feb 16, 2011||Virtual Ports Ltd.||A multi-components device, system and method for assisting minimally invasive procedures|
|EP2359767A2 *||Dec 2, 2003||Aug 24, 2011||Intuitive Surgical, Inc.||Flexible wrist for surgical tool|
|EP2359768A2 *||Dec 2, 2003||Aug 24, 2011||Intuitive Surgical, Inc.||Flexible wrist for surgical tool|
|WO1995018574A1 *||Jan 4, 1995||Jul 13, 1995||Symbiosis Corporation||Flexible microsurgical instrument with rotatable clevis|
|WO1997012557A1 *||Oct 4, 1996||Apr 10, 1997||Kelleher Brian S||Steerable, flexible forceps device|
|WO1998043546A1 *||Mar 5, 1998||Oct 8, 1998||Dicamed Ab||Surgical device|
|WO1998048713A1 *||Apr 29, 1998||Nov 5, 1998||C.R. Bard, Inc.||Directional endoscopic surgical device|
|WO1999055235A1 *||Apr 29, 1999||Nov 4, 1999||Symbiosis Corporation||Endoscopic surgical instrument with deflectable and rotatable distal end|
|WO2005110253A1 *||May 10, 2005||Nov 24, 2005||Olympus Corporation||Surgical treatment device|
|WO2007010208A1 *||Jul 14, 2006||Jan 25, 2007||University Court Of The University Of Dundee||Surgical device for trans-nasal use|
|WO2010101401A2 *||Mar 3, 2010||Sep 10, 2010||Rebo||Surgical instrument|
|WO2010101401A3 *||Mar 3, 2010||Dec 9, 2010||Eterne Inc.||Surgical instrument|
|U.S. Classification||606/206, 606/174, 606/210, 606/167, 606/205, 606/170, 606/207, 600/564|
|International Classification||A61F2/00, A61B17/32, A61B17/00, A61B17/28|
|Cooperative Classification||A61B2017/003, A61B2017/2927, A61F2210/0019, A61F2002/30093, A61B17/29, A61B2017/2929, A61B2017/00331, A61B2017/2905|
|Jun 29, 1992||AS||Assignment|
Owner name: RAYCHEM CORPORATION, CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:PONCET, PHILIPPE;VAN DYKE, KARL;REEL/FRAME:006177/0846;SIGNING DATES FROM 19920624 TO 19920625
|Nov 18, 1996||AS||Assignment|
Owner name: MEDTRONIC, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:RAYCHEM CORPORATION;REEL/FRAME:008907/0388
Effective date: 19961004
|Apr 8, 1997||FPAY||Fee payment|
Year of fee payment: 4
|Mar 29, 2001||FPAY||Fee payment|
Year of fee payment: 8
|Mar 29, 2005||FPAY||Fee payment|
Year of fee payment: 12