|Publication number||US5843126 A|
|Application number||US 08/912,168|
|Publication date||Dec 1, 1998|
|Filing date||Aug 15, 1997|
|Priority date||Aug 15, 1997|
|Also published as||WO1999008606A1|
|Publication number||08912168, 912168, US 5843126 A, US 5843126A, US-A-5843126, US5843126 A, US5843126A|
|Inventors||Irfan M. Jameel|
|Original Assignee||Jameel; Irfan M.|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (26), Non-Patent Citations (1), Referenced by (94), Classifications (12), Legal Events (3)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This invention relates to surgical sutures used to stitch in vivo tissue, and especially to a method and applicator for applying multiple sutures simultaneously.
Surgical sutures allow a surgeon to hold together body tissue. Sutures may be applied singularly or in a series depending upon the length of tissue to be held together. These sutures may be removed after a length of time or absorbed into the body. However, in order to apply multiple sutures to hold two or more fragments of tissue together, removable staples are often required in addition to sutures.
Most suture applicators are designed to apply one suture at a time. In order to apply multiple sutures a temporary suture (stay suture), tissue holding forceps, or a suitable surgical clip or staple must be applied to the tissue to hold the tissue together. The tissue is then stitched with sutures and the temporary suture, clip or staple removed. This dual stitching of the tissue produces more damage to the tissue than the required sutures and is inefficient. This inefficiency may cause problems during surgery where time requirements are essential.
The two major stitching processes used today have also had distinct drawbacks. Continuous stitching involves the use of a single suture which is passed back and forth through the tissue so that a series of continuous stitches is formed. This type of stitching provides a uniform tension which aids in preventing leakage between the sutured tissue. However, as these stitches are formed from a single strand of suture material the breakage or failure of a single stitch causes all the stitches to fail. With interrupt stitching, on the other hand, each stitch is independent of the other. Each stitch is formed by passing the suture material through the tissue, tying off each suture and severing the tied suture from the remaining suture material so that a single stitch remains tied to the tissue. This individualized stitching is continued in series along the length of the treated area. This type of stitching is typically stronger than continuous stitches. Also, the failure of one stitch does not cause all the stitches to fail. However, interrupted stitching does not prevent leakage between tissues and therefore may not be used in the suturing some tissue such as blood vessels or intestines.
Accordingly, it is seen that a need remains for a method of stitching which provides leakage prevention without the possibility of all stitches failing should one stitch break, and a device for applying such. It is to the provision of such therefore that the present invention is primarily directed.
In a preferred form of the invention a multiple surgical suturing apparatus for stitching in vivo tissue of a selected thickness comprises a plurality of prongs having a size greater than the tissue selected thickness and driving means for driving the prongs through the tissue. The prongs have tissue piercing ends and suture retention means for releasably retaining suture material. The apparatus also includes a suture having an elongated base and a plurality of ties extending from the base having a length greater than the selected thickness. With this construction, the prongs are driven through the tissue thereby forcing the ties through the tissue where they may then be tied off against the opposite side of the tissue.
In another form of the invention a method of suturing in vivo tissue comprises the steps of providing a suture having a base and a plurality of ties coupled to the base at one end and having free ends opposite the one ends, passing the free ends of the plurality of sutures through tissue to be sutured, and tieing the free ends of the ties so as to bind the tissue between the base and the tied free ends.
FIG. 1 is a perspective view of a multiple surgical suture applicator embodying principles of the invention is a preferred form.
FIG. 2 is a cross-sectional view of the suture applicator of FIG. 1 shown mounted to tissue.
FIG. 3 is a front view of the suture applicator of FIG. 1 shown with a head portion removed from the prongs.
FIG. 4 is a side view, shown in partial cross-section, which shows a multiple suture having a base and a plurality of ties attached to prongs. The number of prongs correspond to the number of ties.
FIG. 5 is a side view, shown in partial cross-section, of multiple ties being knotted to each other.
FIG. 6 is a side view, shown in partial cross-section, of the ties being tied to a second locking suture.
FIG. 7 is a perspective view of an apparatus for applying the multiple suture in another preferred form.
FIG. 8 is a side view of a suture embodying principles of the invention in another preferred form.
FIG. 9 is a side view of the suture of FIG. 8 shown being tied off.
With reference next to the drawings, there is shown a multiple surgical suturing apparatus 10 having a fastener member 11 and a retainer member 12. The fastener member 11 has a tubular head 13, three removable prongs 14 and a removable locking pin 15 extending through the prongs 14. The tubular head 13 has open ends 17, a series of slots 18 extending into the tubular head 13 and a series of holes 19 extending into the tubular head 13 opposite the slots 18. Each prong 14 has a head portion 21 and a piercing tip 22 having two flexible arms 23 with inwardly facing serrated teeth 24. The head portions 21 of prongs 14 have a hole 26 therethrough sized and shaped to receive locking pins 15. The locking pins 15 have serrated teeth 28 extending along their entire length. The head portion 21 of the prongs 14 also have a recess 29 therein sized and shaped to releasably hold a tie or loop L of suture material. An elongated base suture S is passed through or tied to each tie L.
As best shown in FIG. 2, the retainer member 12 has an internal channel 31 and three passages 32 extending to the internal channel 31. Internal channel 31 has three inverted, V-shaped ridges 33, each aligned with a passage 32. Ridges 33 are defined by diverging slopes 34 having serrated teeth 35 thereon sized and shaped to mate with the serrated teeth 24 of the prong flexible arms 23.
In use, the fastener member 11 is positioned on one side of tissue T to be held with the prongs 14 oriented at an appropriate angle to penetrate the tissue. The retainer member 12 is held on the other side of the tissue T opposite the fastener member 11 with the retainer member passages 32 aligned with the prongs 14. The fastener member 11 and retainer member 12 are brought together thereby forcing the prongs 14 through the tissue T and into the passages 32 of the retainer member. Continued movement of the prongs 14 into the retainer member passages 32 causes the flexible arms 23 to diverge along opposite slopes 34 of ridges 33 whereby the teeth 24 of the arms interlock with the teeth 35 of the ridges, as shown in FIG. 2. The interlocking of teeth 24 and 35 locks the fastener member 11 with the retainer member 12. Relative movement between the fastener member and the retainer member is terminated when the fastener member is positioned an appropriate distance from the retainer member to hold the tissue T securely therebetween. The tissue T between the fastener member and the retainer member is ready to be sutured. As used herein, the term sutured and stitched are equivalents.
The above described method for relative movement of the fastener member in applying the suture to the tissue may be effected with a conventional instrument designed to hold the fastener member and to urge the prongs through the tissue and into the retainer member. Also, instruments which may drive the fastener member from within a blood vessel may be used so that the prongs are driven through the tissue of a blood vessel from within the blood vessel, as with an expanding mechanism such as an angioplasty balloon or laparoscopic mechanisms such as those systems employing movable guide wires, shown schematically in phantom lines in FIG. 2.
The prongs 14 are removed by inserting an instrument I into the slot 18 of the fastener member 11 so as to contact the serrated teeth 28 of the locking pin 15. The instrument for doing such may be a motor driven wheel having teeth sized and shaped to mate with locking pin teeth 28 or simply an elongated probe, also the locking pin may be of any design which retains the prongs in place. These instruments drive the locking pin 15 from within the hole 26 of the prong head portion 21 through the open end 17 of head 13, thereby allowing the prongs 14 to be released from the tubular head 13, as shown in FIG. 3. The prongs 14 are then passed through the tissue in the same direction in which they were inserted. The passing of the prongs 14 through the tissue T forces the ties L through the tissue with the elongated base suture S remaining upon the fastener side of the tissue. As shown in FIG. 4, the ends of the ties L are then released from the prong head portion recess 29. The ends of adjacent ties are knotted to each other, as shown in FIG. 5, thereby capturing the tissue T between the knotted ends of the ties and the elongated base suture S. The tubular head 13, locking pin 15 and retainer member 12 with prongs 14 mounted thereto are removed from the body. As an alternative to knotting the adjoining ties together another elongated locking suture S' may be knotted or passed within the tie loop, to lock each tie, as shown in FIG. 6.
Referring next to FIG. 7, there is shown a suturing apparatus 110 having a lower arm 111 and an upper arm 112 pivotally mounted to each other for scissor like action. The lower arm 111 has four fixedly mounted prongs 113 having a recess 114 therein sized and shaped to receive the loops or ties L of a suture material. An elongated base suture S is passed through or knotted to each tie L. The upper arm 112 has four slots 116 each of which is aligned with a prong 113.
In use, the apparatus works similarly to that previously described except that subsequent to piercing the tissue the prongs 113 are backed out rather than being passed completely through the tissue. As such, the prongs are passed through the tissue, the ties L are released from the prongs, and the prongs are backed out of the tissue leaving the ties L extending through the tissue and the elongated base suture S on the entry side of the tissue. Again, the ties are then knotted to each other as shown in FIG. 5 or tied to a second base or locking suture as shown in FIG. 6.
With reference next to FIGS. 8 and 9, there is shown a suture S wherein portions 200 have been pulled through tissue T with the use of a previously described apparatus. The suture is of a continuous nature with each free end of portion 200 knotted to an adjacent portion 200, as shown in FIG. 9. Hence, if one suture breaks the adjacent tied pair remains intact. Conceptually, the extended portions 200 are equivalent to the previously described loops or ties, as such the extended portions should also be considered ties herein.
The just described multiple sutures incorporate the advantages of both continuous stitching and interrupted stitching while eliminating the disadvantages associated with each. The multiple suturing provides a tight, continuous pressure and uniform tension along the entire length of the stitching to minimize leakage between the adjoining tissues, similarly to continuous stitching and dissimilarly to interrupted stitching. Also, the multiple suturing provides a stitching which will not become completely undone or inoperative should a single tie become broken, similarly to interrupted stitching and dissimilarly to continuous stitching. Thus, it should be understood that the just described invention provides a uniquely uniform tension with the safety advantage of providing substantial tension should a single suture break or otherwise loosen.
It thus is seen that a simultaneous, multiple surgical sutures may now be formed which provide a uniform tension in a safe and efficient manner. It should be understood that the number of prongs and alignment may be varied according to the size and shape of the tissue to be held. As such, the apparatus may be provided with as little as two prongs. Also, the prong may be provided with any type of means for retaining suturing material, such as clips, as an alternative to the recess. Lastly, the suture ties L may be looped only at the ends thereof rather than the entire length of the looped portion or formed without a loop so long as they are capable of being releasably held by the prongs.
While this invention has been described in detail with particular references to the preferred embodiment thereof, it should be understood that many modifications, additions and deletions, in addition to those expressly recited, may be made thereto without departure from the spirit and scope of the invention as set forth in the following claims.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US19747 *||Mar 30, 1858||Byron boardman|
|US262635 *||Dec 8, 1881||Aug 15, 1882||Staple|
|US356202 *||Jan 18, 1887||Ments|
|US1678361 *||Jun 25, 1927||Jul 24, 1928||Sharp & Smith||Surgical needle|
|US2058020 *||May 17, 1935||Oct 20, 1936||Jaffe Elias||Self-fastening button|
|US2213830 *||Dec 10, 1938||Sep 3, 1940||Joseph Anastasi John||Suturing and ligating instrument|
|US2738789 *||Nov 12, 1954||Mar 20, 1956||Martha K Foxworthy||Disposable abdominal band|
|US2738790 *||Aug 12, 1954||Mar 20, 1956||George P Pilling & Son Company||Suturing instrument|
|US3139089 *||Nov 16, 1961||Jun 30, 1964||George S Schwerin||Needle manipulating device|
|US3515194 *||Mar 17, 1969||Jun 2, 1970||Acme Staple Co Inc||Threaded staple|
|US4060089 *||Sep 3, 1975||Nov 29, 1977||United States Surgical Corporation||Surgical fastening method and device therefor|
|US4454875 *||Apr 15, 1982||Jun 19, 1984||Techmedica, Inc.||Osteal medical staple|
|US4534350 *||Jun 20, 1983||Aug 13, 1985||Ethicon, Inc.||Two-piece tissue fastener with compressible leg staple and retaining receiver|
|US4610250 *||Oct 8, 1985||Sep 9, 1986||United States Surgical Corporation||Two-part surgical fastener for fascia wound approximation|
|US4946458 *||Feb 28, 1989||Aug 7, 1990||Harms Juergen||Pedicle screw|
|US4957498 *||Nov 7, 1989||Sep 18, 1990||Concept, Inc.||Suturing instrument|
|US5015250 *||Jan 12, 1990||May 14, 1991||Vance Products Incorporated||Medical instrument for driving a suture needle|
|US5222977 *||Feb 21, 1992||Jun 29, 1993||Esser Rene D||Surgical needle with an adjustable eye|
|US5224948 *||Oct 23, 1991||Jul 6, 1993||Ethicon, Inc.||Suturing device for multiposition holding of suture needles|
|US5258011 *||Jun 4, 1990||Nov 2, 1993||Drews Robert C||Corneal rivet|
|US5281237 *||Sep 25, 1992||Jan 25, 1994||Gimpelson Richard J||Surgical stitching device and method of use|
|US5374275 *||Mar 25, 1993||Dec 20, 1994||Synvasive Technology, Inc.||Surgical suturing device and method of use|
|US5417701 *||Mar 30, 1993||May 23, 1995||Holmed Corporation||Surgical instrument with magnetic needle holder|
|US5501691 *||May 2, 1994||Mar 26, 1996||Goldrath; Milton H.||Verres needle suturing device|
|US5522820 *||Nov 9, 1994||Jun 4, 1996||Arthrotech||Method and apparatus for suturing tissue|
|US5584856 *||Dec 21, 1994||Dec 17, 1996||Jameel; Irfan M.||Removable surgical staple|
|1||*||Laparoscopic Suturing and Tissue Approximation by Zoltan Szabo, Ch. 19.|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US6610071||Jul 26, 1999||Aug 26, 2003||Beth Israel Deaconess Medical Center||Suture system|
|US6746456 *||Sep 28, 2001||Jun 8, 2004||Ethicon, Inc.||Needle array suturing/sewing anastomosis device and method for anastomosis|
|US7678135||Apr 14, 2006||Mar 16, 2010||Usgi Medical, Inc.||Compressible tissue anchor assemblies|
|US7695493||Jun 9, 2004||Apr 13, 2010||Usgi Medical, Inc.||System for optimizing anchoring force|
|US7703459||Sep 29, 2004||Apr 27, 2010||Usgi Medical, Inc.||Apparatus and methods for mapping out endoluminal gastrointestinal surgery|
|US7704264||Nov 17, 2004||Apr 27, 2010||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US7736374||Mar 1, 2005||Jun 15, 2010||Usgi Medical, Inc.||Tissue manipulation and securement system|
|US7736378||May 7, 2004||Jun 15, 2010||Usgi Medical, Inc.||Apparatus and methods for positioning and securing anchors|
|US7736379||Jul 11, 2005||Jun 15, 2010||Usgi Medical, Inc.||Compressible tissue anchor assemblies|
|US7744613||Dec 12, 2003||Jun 29, 2010||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US7871411 *||Aug 3, 2006||Jan 18, 2011||Mark Grevious||Sternal closure device|
|US7918845||Nov 16, 2004||Apr 5, 2011||Usgi Medical, Inc.||Endoluminal tool deployment system|
|US7918869||May 7, 2004||Apr 5, 2011||Usgi Medical, Inc.||Methods and apparatus for performing endoluminal gastroplasty|
|US7942884||Jul 1, 2003||May 17, 2011||Usgi Medical, Inc.||Methods for reduction of a gastric lumen|
|US7942898||Jul 1, 2003||May 17, 2011||Usgi Medical, Inc.||Delivery systems and methods for gastric reduction|
|US7955340||Dec 12, 2003||Jun 7, 2011||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US8057511||May 7, 2004||Nov 15, 2011||Usgi Medical, Inc.||Apparatus and methods for positioning and securing anchors|
|US8066719||Nov 18, 2004||Nov 29, 2011||Ewers Richard C||Apparatus and methods for forming gastrointestinal tissue approximations|
|US8097005||Aug 25, 2003||Jan 17, 2012||Beth Israel Deaconess Medical Center||Suture system|
|US8097023 *||Feb 12, 2007||Jan 17, 2012||Warsaw Orthopedic, Inc.||Grommet assembly|
|US8128642 *||Apr 22, 2009||Mar 6, 2012||Tyco Healthcare Group Lp||Fluid delivery system for surgical instruments|
|US8177796||Mar 22, 2010||May 15, 2012||Linvatec Corporation||Suture passing apparatus and method|
|US8206417||Jun 9, 2004||Jun 26, 2012||Usgi Medical Inc.||Apparatus and methods for optimizing anchoring force|
|US8216252||Mar 1, 2005||Jul 10, 2012||Usgi Medical, Inc.||Tissue manipulation and securement system|
|US8216253||Apr 22, 2008||Jul 10, 2012||Usgi Medical, Inc.||Apparatus for manipulating and securing tissue|
|US8216260||Aug 25, 2008||Jul 10, 2012||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US8236009||Oct 14, 2009||Aug 7, 2012||Usgi Medical, Inc.||Needle assembly for tissue manipulation|
|US8257394||Jan 14, 2005||Sep 4, 2012||Usgi Medical, Inc.||Apparatus and methods for positioning and securing anchors|
|US8262676||Sep 18, 2009||Sep 11, 2012||Usgi Medical, Inc.||Apparatus and methods for forming gastrointestinal tissue approximations|
|US8298291||Apr 26, 2006||Oct 30, 2012||Usgi Medical, Inc.||Methods and apparatus for securing and deploying tissue anchors|
|US8308765||May 7, 2004||Nov 13, 2012||Usgi Medical, Inc.||Apparatus and methods for positioning and securing anchors|
|US8313509||Jan 19, 2010||Nov 20, 2012||Covidien Lp||Suture and retainer assembly and SULU|
|US8343175||Apr 26, 2010||Jan 1, 2013||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US8381961 *||Dec 4, 2009||Feb 26, 2013||Covidien Lp||Surgical stapling apparatus including staple with plate|
|US8382800||Mar 15, 2010||Feb 26, 2013||Usgi Medical, Inc.||Compressible tissue anchor assemblies|
|US8435254||Oct 23, 2012||May 7, 2013||Covidien Lp||Suture and retainer assembly and sulu|
|US8444657||Apr 28, 2005||May 21, 2013||Usgi Medical, Inc.||Apparatus and methods for rapid deployment of tissue anchors|
|US8449533||May 2, 2012||May 28, 2013||Ceterix Orthopaedics, Inc.||Devices, systems and methods for meniscus repair|
|US8465505||May 2, 2012||Jun 18, 2013||Ceterix Orthopaedics, Inc.||Suture passer devices and methods|
|US8500809||Jan 10, 2012||Aug 6, 2013||Ceterix Orthopaedics, Inc.||Implant and method for repair of the anterior cruciate ligament|
|US8562631||Nov 9, 2010||Oct 22, 2013||Ceterix Orthopaedics, Inc.||Devices, systems and methods for meniscus repair|
|US8574243||Dec 12, 2003||Nov 5, 2013||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US8597262||Aug 16, 2010||Dec 3, 2013||Ams Research Corporation||Apparatus and methods of treatment of pathologic proliferative conditions uterine tissue|
|US8641730 *||Aug 18, 2009||Feb 4, 2014||Covidien Lp||Local biomechanical and/or antimicrobial ligation device|
|US8663253||Apr 19, 2011||Mar 4, 2014||Ceterix Orthopaedics, Inc.||Methods of meniscus repair|
|US8702731||May 24, 2011||Apr 22, 2014||Ceterix Orthopaedics, Inc.||Suturing and repairing tissue using in vivo suture loading|
|US8726909||Jan 27, 2006||May 20, 2014||Usgi Medical, Inc.||Methods and apparatus for revision of obesity procedures|
|US8740940||Jan 23, 2013||Jun 3, 2014||Usgi Medical, Inc.||Compressible tissue anchor assemblies|
|US8808299||Apr 30, 2013||Aug 19, 2014||Ceterix Orthopaedics, Inc.||Devices, systems and methods for meniscus repair|
|US8821518||Nov 5, 2008||Sep 2, 2014||Ceterix Orthopaedics, Inc.||Suture passing instrument and method|
|US8828027||Jun 14, 2010||Sep 9, 2014||U.S.G.I. Medical, Inc.||Tissue manipulation and securement system|
|US8870916||Jul 5, 2007||Oct 28, 2014||USGI Medical, Inc||Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use|
|US8888848||May 13, 2013||Nov 18, 2014||Ceterix Orthopaedics, Inc.||Implant and method for repair of the anterior cruciate ligament|
|US8900256||Feb 2, 2012||Dec 2, 2014||Covidien Lp||Fluid delivery system for surgical instruments|
|US8911456||Feb 4, 2013||Dec 16, 2014||Ceterix Orthopaedics, Inc.||Methods and devices for preventing tissue bridging while suturing|
|US8920441||May 2, 2012||Dec 30, 2014||Ceterix Orthopaedics, Inc.||Methods of meniscus repair|
|US8926634||Dec 5, 2007||Jan 6, 2015||Usgi Medical, Inc.||Apparatus and methods for manipulating and securing tissue|
|US8940000||May 12, 2010||Jan 27, 2015||Covidien Lp||Surgical instruments with flexible member attachment structures|
|US9011454||Apr 30, 2014||Apr 21, 2015||Ceterix Orthopaedics, Inc.||Suture passer with radiused upper jaw|
|US9072343||Jan 2, 2014||Jul 7, 2015||John W. Ogilvie||Multigrip touch closure fasteners|
|US9101338 *||May 3, 2007||Aug 11, 2015||Mayo Foundation For Medical Education And Research||Soft body tissue remodeling methods and apparatus|
|US9186134 *||Apr 17, 2013||Nov 17, 2015||Covidien Lp||Suture and retainer assembly and SULU|
|US9211119||Mar 15, 2013||Dec 15, 2015||Ceterix Orthopaedics, Inc.||Suture passers and methods of passing suture|
|US9247934||May 13, 2013||Feb 2, 2016||Ceterix Orthopaedics, Inc.||Suture passer devices and methods|
|US9247935||Sep 23, 2014||Feb 2, 2016||Ceterix Orthopaedics, Inc.||Arthroscopic knot pusher and suture cutter|
|US9265514||Apr 17, 2012||Feb 23, 2016||Miteas Ltd.||Manipulator for grasping tissue|
|US9289207 *||Nov 29, 2012||Mar 22, 2016||Ethicon Endo-Surgery, Llc||Surgical staple with integral pledget for tip deflection|
|US9314234||Feb 4, 2013||Apr 19, 2016||Ceterix Orthopaedics, Inc.||Pre-tied surgical knots for use with suture passers|
|US9332980||Jan 28, 2015||May 10, 2016||Ceterix Orthopaedics, Inc.||Arthroscopic knot pusher and suture cutter|
|US9468434||Oct 7, 2014||Oct 18, 2016||Covidien Lp||Stitching end effector|
|US9492162||Dec 16, 2014||Nov 15, 2016||Ceterix Orthopaedics, Inc.||Automatically reloading suture passer devices and methods|
|US9510817||Jun 7, 2012||Dec 6, 2016||Usgi Medical, Inc.||Apparatus for manipulating and securing tissue|
|US9585651||May 26, 2005||Mar 7, 2017||Usgi Medical, Inc.||Methods and apparatus for securing and deploying tissue anchors|
|US9610088||Apr 1, 2015||Apr 4, 2017||A-Base Korlatolt Felelossegu Tarsasag||Manipulator for grasping tissue|
|US9636103||Feb 18, 2015||May 2, 2017||Covidien Lp||Surgical suturing instrument|
|US9700299||Dec 12, 2011||Jul 11, 2017||Ceterix Orthopaedics, Inc.||Suture passer devices and methods|
|US20030065336 *||Sep 28, 2001||Apr 3, 2003||Xiao Jia Hua||Needle array suturing/sewing anastomosis device and method for anastomosis|
|US20040106949 *||Aug 25, 2003||Jun 3, 2004||Beth Israel Deaconess Medical Center||Suture system|
|US20060287658 *||Jun 6, 2006||Dec 21, 2006||Mujwid James R||Devices and Methods for Ligating Uterine Arteries|
|US20070038218 *||Aug 3, 2006||Feb 15, 2007||Mark Grevious||Sternal closure device|
|US20070162008 *||Feb 12, 2007||Jul 12, 2007||Warsaw Orthopedic, Inc.||Grommet assembly|
|US20070282375 *||May 3, 2007||Dec 6, 2007||St. Jude Medical, Inc.||Soft body tissue remodeling methods and apparatus|
|US20090182374 *||Jan 10, 2008||Jul 16, 2009||John Keith||Surgical staple|
|US20090275902 *||Apr 22, 2009||Nov 5, 2009||Andrew Heeps||Fluid delivery system for surgical instruments|
|US20100217314 *||Dec 4, 2009||Aug 26, 2010||Holsten Henry E||Surgical stapling apparatus including staple with plate|
|US20110046647 *||Aug 18, 2009||Feb 24, 2011||Andrew Heeps||Local Biomechanical and/or Antimicrobial Ligation Device|
|US20110178536 *||Jan 19, 2010||Jul 21, 2011||Tyco Healthcare Group Lp||Suture and retainer assembly and sulu|
|US20130245645 *||Apr 17, 2013||Sep 19, 2013||Covidien Lp||Suture and retainer assembly and sulu|
|US20140144968 *||Nov 29, 2012||May 29, 2014||Ethicon Endo-Surgery, Inc.||Surgical staple with integral pledget for tip deflection|
|US20160051282 *||Mar 27, 2015||Feb 25, 2016||Attenuex Technologies, Inc.||Methods and systems for performing a medical procedure|
|EP2345372A3 *||Jan 19, 2011||Jul 27, 2011||Tyco Healthcare Group LP||Suture and retainer assembly|
|EP2944268A1 *||Jan 19, 2011||Nov 18, 2015||Covidien LP||Suture and retainer assembly and sulu|
|WO2001006935A1 *||Jul 21, 2000||Feb 1, 2001||Beth Israel Deaconess Medical Center||Suture system|
|WO2010094730A1 *||Feb 18, 2010||Aug 26, 2010||Commissariat A L'energie Atomique Et Aux Energies Alternatives||Device for connecting two hollow biological tissues by sutures|
|U.S. Classification||606/220, 606/144, 606/139, 606/218, 606/148|
|International Classification||A61B17/04, A61B17/06|
|Cooperative Classification||A61B2017/0472, A61B17/06, A61B17/0483|
|European Classification||A61B17/04H, A61B17/06|
|Jun 18, 2002||REMI||Maintenance fee reminder mailed|
|Dec 2, 2002||LAPS||Lapse for failure to pay maintenance fees|
|Jan 28, 2003||FP||Expired due to failure to pay maintenance fee|
Effective date: 20021201