|Publication number||US6875170 B2|
|Application number||US 10/274,454|
|Publication date||Apr 5, 2005|
|Filing date||Oct 21, 2002|
|Priority date||Apr 21, 2000|
|Also published as||CA2406522A1, CA2406522C, DE60121316D1, DE60121316T2, EP1274480A1, EP1274480B1, US20030149338, WO2001080935A1|
|Publication number||10274454, 274454, US 6875170 B2, US 6875170B2, US-B2-6875170, US6875170 B2, US6875170B2|
|Inventors||Christian Francois, Frank Boudghene, Pierre Joli|
|Original Assignee||Universite Pierre Et Marie Curie|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (21), Non-Patent Citations (2), Referenced by (40), Classifications (25), Legal Events (3)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This is a Continuation-in-Part of PCT/FR01/01050 filed on Apr. 6, 2001 and published in French.
The invention relates to positioning, exploration, and/or intervention devices in particular for medico-surgical instruments such as catheters, endoscopes, or celiolaparoscopes. It also relates to various industries that may need to use devices of this type of a size that can lie in the range a few millimeters to several decimeters.
Medical and surgical instruments such as endoscopes or catheters are known for penetrating into ducts or cavities of the human body (vessels, digestive or urinary tract, etc.) for observation or intervention purposes. One of the main difficulties raised by such instruments is that they must be capable of deforming so as to follow the curvature of the duct or cavity along which they are progressing or so as to take one of two paths at a branch or so as to avoid an obstacle, and this must damage tissue as little as possible. The problem arises, for example, when it is desired to treat an aneurysm by installing an aortic prosthesis. For this purpose, instruments are known which are deformed by means of internal cables that are pulled or pushed so as to curve the instrument in one direction or the other. That applies for example to document EP-0 788 807. Nevertheless, instruments curved by pulling on cables cannot take up very sharp curves which can make progress complicated. Furthermore, those instruments often lack flexibility and are too rigid. The document “A micro-robotic system for colonoscopy”, Proceedings of the 1997 IEEE Internal Conference on Robotics and Automation, Albuquerque, N.Mex., April 1997, presents an instrument whose body is made with a bellows enabling it to be lengthened or shortened at will, and capable of advancing like a worm in a duct. However, that device still does not make it possible to impart a predetermined sharp curvature to the instrument.
In another context, numerous industrial applications require the lack of accuracy of machines or robots to be made good by a device for fine repositioning of an end tool or of a part being carried. For example, it can be necessary to align marks on two parts to be engaged one in the other (repositioning during insertion), or else to minimize contact forces between a tool and a workpiece (e.g. removing flash).
Three types of system are used for this purpose:
In those fields also, it is desirable to have a positioning, exploration, and/or intervention device that is capable of combining a large amount of controlled curvature with flexibility.
An object of the invention is to provide a positioning, exploration, and/or intervention device that is suitable for being controlled to obtain pronounced curvature while nevertheless being capable of presenting substantial flexibility.
According to the invention, in order to achieve this object, there is provided a positioning, intervention, and/or exploration device having two endpieces and at least one cable extending from one endpiece to the other, the device comprising at least two bellows each fixed directly to the two endpieces, and means for modifying the pressure of a fluid in each of the bellows independently of the other bellows.
Thus, the two bellows make it possible to modify the length of the device by modifying the pressure in each of the bellows while conserving equal pressures between the bellows at all times. It is thus possible to lengthen or shorten the device. In addition, the pressures in the bellows can be made to be different from each other in order to curve the device. It is also possible to combine these two types of movement. It is found in practice that the bellows enable the device to obtain sharper curvature than is possible in conventional devices controlled solely by cable. This is due in particular to the fact that curvature can be the result both of high pressure in one bellows and low pressure in another bellows, whereas the cables of known devices work essentially in traction only. Furthermore, the device is deformed by acting on the existence and the amplitude of a pressure difference, i.e. by controlling relative pressure. However, the device also makes it possible to select the absolute pressures that exist in the bellows so as to vary the flexibility or the stiffness of the device. Thus, working with high pressures makes the device rigid against external forces. In contrast, working with low pressures makes the device relatively flexible, deformable, and of little danger to its surroundings, which is a significant advantage for applications in the medical field. Controlling pressure makes it possible to vary the stiffness of the device at will. In particular, the device can be given maximum stiffness or on the contrary maximum flexibility. That is why such a positioning, exploration, and/or intervention device is particularly advantageous in the medical field (surgery, . . . ) as well as in numerous industries.
Furthermore, the curvature of the device is thus controlled at will by the bellows and/or by one or more cables.
Advantageously, the device comprises at least three bellows each fixed to both endpieces.
Thus, the device can be curved in any direction.
Advantageously, the device includes at least one cable extending from one endpiece to the other.
Advantageously, the or each cable is fixed to at least one of the endpieces and/or is movable relative to at least one of the endpieces.
Advantageously, the or each cable is off-center relative to the longitudinal axis of the device.
Advantageously, the or each cable extends outside the bellows.
Advantageously, the device includes feed tubes for feeding the bellows with fluid, the or each cable passing outside the tubes.
Advantageously, the or each cable carries at least one block suitable for coming into abutment against at least one of the endpieces during certain deformations of the device.
Advantageously, the or each cable carries at least two blocks suitable for coming into abutment in two opposite directions against the two endpieces.
Advantageously, the cables are two in number per bellows and are disposed on either side of the bellows.
Advantageously, the device has at least three endpieces disposed in succession, and for each successive pair of endpieces, it has at least two bellows each fixed to two endpieces.
The device thus presents at least two stages whose curvatures can be added or combined.
Advantageously, for each successive pair or endpieces the device includes means for modifying the pressure of a fluid in each of the bellows fixed to the endpieces of the pair, and for doing so independently of the other bellows fixed to the endpieces of the pair.
Advantageously, the means for modifying the pressure are suitable for modifying the pressure in each of the bellows fixed to the endpieces of one of the pairs, and for doing so independently of the bellows fixed to the endpieces of the other pair or of another pair amongst the pairs of endpieces.
Advantageously, the two bellows of one of the pairs of endpieces are in fluid communication with the respective bellows of the other pair or of another pair amongst the pairs of endpieces.
Advantageously, the device includes at least one spacer disposed to prevent two endpieces moving closer together or to prevent two of the endpieces moving closer together beyond a predetermined value.
Advantageously, each bellows is capable of lengthening and of shortening along a longitudinal direction of the bellows under the effect of the fluid without substantial modification of the dimension of the bellows perpendicularly to the longitudinal direction.
Thus, the bends of two stages can be in different planes or they can be in the same plane. Under such circumstances, they can extend in the same direction or in opposite directions.
Advantageously, the device has an inner first sheath fixed to a proximal one of the endpieces, and an outer second sheath receiving the endpieces and suitable for sliding in the inner first sheath.
Thus, the length of the device can be modified by acting on the bellows without harming sealing between the outside and the inside of the device.
Advantageously, the fluid is a liquid.
Advantageously, variations in liquid pressure or in cable tension can be combined so as to modify the stiffness and the orientation of the device.
Advantageously, the device has an empty longitudinal space extending from one end of the device to the other.
This space can receive elements for intervention, observation, etc.
Advantageously, the empty longitudinal space allows instruments or waveguides to be passed therealong.
The invention also provides a medico-surgical instrument including a device of the invention for positioning, exploration, and/or intervention.
Advantageously, it is a catheter.
Advantageously, it is an endoscope.
Other characteristics and advantages of the invention appear further in the following description of two preferred embodiments and of variants given as non-limiting examples. In the accompanying drawings:
A first embodiment of the invention is described with reference to
The endpieces 6 a and 6 b form one pair while the endpieces 6 c and 6 d form another pair. Each of these two pairs is associated with a plurality of bellows 10, there being three bellows for each pair in this case. All six bellows 10 are identical. They are generally in the form of elongate cylinders parallel to the axis 8. The three bellows for each pair of endpieces are uniformly distributed around the axis 8. Each bellows has its ends fixed to the two endpieces of the corresponding pair, and specifically to axial end faces thereof. The distal axial end of each bellows is closed.
The device has six ducts 12, one for each bellows 10, all of the ducts extending parallel to the axis 8. Three of the ducts terminate in the proximal endpiece 6 d via its proximal axial end face remote from the bellows. They pass through the endpiece 6 d and are in fluid communication inside the endpiece with the proximal axial ends of three respective bellows. The other three ducts 12 pass through the two endpieces 6 d and 6 c at regular spacing around the axis 8, each being positioned between two adjacent bellows of that pair of endpieces. These three ducts are free to slide through orifices in the two endpieces 6 c and 6 d. Thereafter, the three ducts pass through the space between the two modules 4 and reach the proximal end of the endpiece 6 b.
The radial positioning and the spacing of these ducts can be chosen so as to leave a central channel of greater or smaller diameter and a peripheral space of greater or smaller size enabling a folded annular sleeve (endoprosthesis) to be received possibly together with a release device therefor (inflatable balloon). Inside the endpiece 6 b, the ducts are put into fluid communication with the three bellows 10 associated with said endpiece. It follows from the above arrangement that the two groups of three bellows are offset from each other by one-sixth of a turn about the axis 8, in axial view. The six ducts 12 can be uniformly distributed around the axis 8. The same applies to the three ducts 12 associated with each pair of endpieces. Each duct 12 is in fluid communication with its associated bellows and together therewith it constitutes an assembly that is leakproof relative to the other ducts and bellows.
All of these elements of the device are enclosed in a flexible sheath 14 that can be connected in leakproof manner to the distal endpiece 6 a. The spacing between the two endpieces 6 b and 6 c is maintained whatever the configuration of the device by means of spacers 16 contiguous with the sheath 14 and bearing against the facing axial ends of the endpieces 6 b and 6 c. The length of the spacers can be selected so as to obtain a predetermined spacing between the endpieces 6 b and 6 c. Alternatively, one of these two endpieces 6 b and 6 c could be omitted so as to cause the distal endpiece of one of the modules to form the proximal endpiece of the other module.
The sheath 14 can slide so as to leave space between the endpieces 6 b and 6 c, thereby enabling the endoprosthesis that is folded up in said space to be released. As a result, the sheath 14 need not be connected to the distal endpiece 6 a in leakproof manner. The three feed ducts situated between the endpieces 6 b and 6 c can be closer together radially than the other three ducts so as to leave a large amount of peripheral space between the endpieces 6 b and 6 c.
The bellows are elastic and can be lengthened, shortened, and/or curved. The device has means 18 for injecting a fluid under pressure, in this case a liquid such as physiological serum, into each of the ducts 12 (and the associated bellows). These means make it possible to determine the pressure in each of the bellows independently of the other bellows. Such pressure feed and control means are known per se and are not shown in detail. In rudimentary form they could be constituted by a set of six declutchable non-return syringes associated with respective ones of the various ducts 12. In a more elaborate form, these means could be constituted by a distributor valve suitable for feeding the various ducts as a function of a general curvature command given by a suitable device, e.g. a keypad, a joystick, or even voice command. These control means are located at a distance from the endpieces and remain outside the body in the present case of medico-surgical exploration.
In this case, they are provided so as to be able to lengthen and shorten along their longitudinal direction under the effect of the fluid without substantial modification of a radial dimension of the bellows.
There follows a description of how the module 4 is deformed. To lengthen it without curving it, it suffices to increase the pressure in each of the bellows 10 so that the instantaneous pressure is the same in all three bellows. Similarly, decreasing the pressure uniformly in all three bellows will shorten the module. To curve the module, it suffices to deliver higher pressure to one or both bellows 10 1 situated on the side opposite from the center of curvature O as shown in FIG. 5. Thus, these bellows lengthen so as to become longer than the other bellows 10 2, thereby causing relative inclination to be established between the endpieces 6 and causing the device to curve. Naturally, both of those deformations can be combined within the same module so as to cause its length and its curvature to vary simultaneously.
The six control ducts 12 enable each stage to be deformed in completely independent manner as shown in
The deformations obtained by such a device are greater than those which can be obtained with a device that is controlled by cables only, in particular because cables generally work in traction. In contrast, the present device can be controlled in such a manner that at least one of its bellows is working under raised pressure while the other is working under lowered pressure such that their combined actions both serve to curve the stage in the same direction.
The device presents an empty central space on its axis 8, which space is uninterrupted along the entire length of the device. This space extends between the bellows 10, between the ducts 12, and it is defined by respective central orifices through the endpieces 6. This space can be used to house any selected instrument, tool, camera, liquid injection hose, electric cables, optical fibers, light rays, laser beams, viewing device, surgical instruments, needles, biopsy needles, fastening devices, etc. (clamps, clips, chisel, . . . ).
Each module 4 can be miniaturized so as to be of a length shorter than 2 cm and of a diameter less than 5 mm.
The embodiment of
Thus, the module can be shortened by reducing the pressure in the bellows. It can also be shortened by exerting an equal traction force on three control cables. In order to curve the module, the pressure can be varied from one bellows of the module to the other, as explained with reference to the first embodiment. In addition, the bellows 10 2 can simultaneously be shortened by traction on the cables, thereby increasing the overall curvature of the device. The combination of the effect of the pressure and of the cable traction in each bellows enables the stiffness of the device to be varied.
In each of these embodiments, it is possible to avoid the risk of the bellows 10 buckling by surrounding each of them with a cylindrical spacer 22 that is shorter than the shortest design length of the bellows, as shown in chain-dotted lines in FIG. 2.
In the embodiment of
The (outer) sheath 14 can slide over the (inner) sheath 24. The sheath 24 serves to hold the device as a whole in longitudinal position since when it is prevented from moving, the endpiece 6 d bears against it and therefore cannot reverse while the sheath 14 is shrinking.
A third embodiment is shown in
Replacing each bellows of the first embodiment by two bellows disposed in series and controlled simultaneously allows the variation in length and in curvature of each stage to be increased in amplitude.
Furthermore, the intermediate endpiece 7 provides a spacer function, thereby preventing the bellows from buckling, which could occur if the bellows of the first or second embodiment were very long.
Furthermore, in this embodiment, each stage is associated exclusively as a group with six cables 20. The entire device therefore includes twelve cables 20. In this case, the cables extend out of the bellows and the ducts 12. Each pair of bellows is associated with two cables extending on either side of the bellows as can be seen in
The endpiece presents twelve secondary orifices 34 associated in pairs with the main orifices and extending in the vicinity of said main orifices. The secondary orifices serve to receive the cables of the two stages. Naturally, on the endpieces of the distal stage, the number of main and secondary orifices can be reduced by half so as to avoid having unused orifices.
In this embodiment, each cable 20 is movable relative to all of the endpieces 6, 7. For each main endpiece to which each cable 12 is designed to be effectively connected, the cable carries a block 36 formed, for example, by a knot in the cable or by a part bonded or welded to the cable. The block prevents the cable from sliding in a certain direction and beyond a certain limit in the orifice 34 of the associated endpiece. Each cable carries two blocks disposed so that the cable limits the distance through which the two associated endpieces can move apart.
Each of the most distal blocks is used when it is desirable to shorten the device. The two blocks of each cable serve, in co-operation, to prevent plastic deformation of the bellows during a lengthening maneuver.
The endpieces can be made of a metal, a plastics material, or a composite material. The bellows can be made of a metal, a plastics material, or a composite material. The bellows can be secured to the endpieces in leakproof manner by adhesive, brazing, soldering, screw fastening, riveting, . . . The same applies to the hoses for feeding fluid under pressure which must be flexible and capable of withstanding the maximum pressures that the bellows can accept.
The endpieces can also possess recesses for purging air from the volumes under pressure (bellows 10, feed hoses 12) when using fluids other than air, and in particular when using liquids. These recesses can be closed by plugs so as to seal them after purging. The endpieces can also present recesses for receiving sensors or systems for receiving tools, of the forceps, cutting forceps, scissors, clamp, needle carrier, biopsy needle, suction nozzle, etc. type.
The device may have position sensors, e.g. ultrasound sensors for making it easier for the operator to guide it from the outside.
The cables can be made of shape memory alloy so as to lengthen or shorten under the action of temperature variations.
The bellows preferably have electroplated nickel.
The positioning device of the invention can be designed for single use (to be discardable).
Because the endpieces can move in translation and in rotation relative to one another, numerous applications can be envisaged.
1) In the Medico-Surgical Field
In this field, since the size of the device is not a limiting factor, it can lie in the range a few millimeters to several decimeters. Applications are as follows:
Other applications can be envisaged in numerous other fields, whenever it is desirable to be able to steer one solid in three dimensions relative to another.
Naturally, numerous modifications can be applied to the invention without going beyond the ambit thereof. The number of stages can be one, two, three, or more. The number of bellows per stage can be equal to two, three, or more.
In the embodiments described above, although less advantageous, it is possible to provide for the bellows in the two stages to be connected together in series, at least in pairs, so that there are only three ducts 12, each controlling two bellows, i.e. at least one bellows in each stage. Naturally, under such circumstances, those two bellows can no longer be controlled independently of each other. However, the amplitude of axial deformation of each bellows and the lengthening of each module is increased.
The wall of each bellows could have a profile having a shape that is different from the ziz-zag shape shown in the figures. The wall could be a cylindrically shaped wall provided to present elasticity in the longitudinal direction but not in the radial direction.
The cables could be made of any plastics material, in particular polymer such as nylon, dacron, kevlar, or could be made of metal.
A fifth and preferred embodiment of the invention is shown on
This embodiment is very close to the previous ones and the same elements have the same numeral references.
Here, between any couple of endpieces following each other, for example the endpieces 6 b-6 c, the device comprises at least one and preferably at least two radial spacers 40. The two spacers are aligned with the two endpieces along axis 8 so that the order of the succession is: endpiece 6 b, spacer 40, spacer 40, endpiece 6 c. One of the spacer is disposed at one third of the length between the endpieces, and the other spacer at two thirds of this length. Each spacer 40 roughly has the same shape as the endpieces 6 b, 6 c but is shorter along axis 8. Its shape in plan view is a disc. It has the central channel 32 and three orifices 30 for housing three bellows respectively, bellows which extend from endpiece 6 b to endpiece 6 c, these orifices 30 being smaller in diameter than the channel 32. It also has ten orifices 34 for the respective cables 12. The three orifices 30 are open laterally on their side directed toward the radial periphery of the spacer. But the corresponding opening 42 is small enough to forbid the bellow from exiting the orifice laterally.
Each bellow 10 passes through both spacers 40. It shows two portions 44 aimed to extend inside the orifices 30, adjacent the respective spacers. Each portion 44 is smooth and deprived of corrugation, contrary to the other portions 46 of the bellow extending between the spacers or between a spacer and an endpiece. The diameter of the smooth portions 44 is smaller than the diameter of the portions 46.
These spacers are aimed to prevent any of the bellows from moving radially with reference to the longitudinal axis 8, that is to say from moving in any direction perpendicular to axis 8. Their presence permits to reduce the total width of the device.
An advantage of the device according to the invention is generally that it uses no electrical current for moving the device. Accordingly, it can be introduced in a duct of a human body without any danger. Beside, no electrical interaction risks to alter the working of another medical device, such as an imaging scanner used to follow the path of the device inside the body.
Advantageously, the device will include at least one force sensor and/or at least one sensor for measuring distance in order to detect a contact of the device with a wall of the duct and make easier to precisely locate at least one part of the device.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US4140126||Feb 18, 1977||Feb 20, 1979||Choudhury M Hasan||Method for performing aneurysm repair|
|US4676228 *||Oct 25, 1985||Jun 30, 1987||Krasner Jerome L||Medical apparatus having inflatable cuffs and a middle expandable section|
|US4794912||Aug 17, 1987||Jan 3, 1989||Welch Allyn, Inc.||Borescope or endoscope with fluid dynamic muscle|
|US4832473 *||Feb 1, 1988||May 23, 1989||Olympus Optical Co., Ltd.||Endoscope with elastic actuator comprising a synthetic rubber tube with only radial expansion controlled by a mesh-like tube|
|US4893613 *||Oct 21, 1988||Jan 16, 1990||Hake Lawrence W||Endoscope construction with means for controlling rigidity and curvature of flexible endoscope tube|
|US5042707||Oct 16, 1990||Aug 27, 1991||Taheri Syde A||Intravascular stapler, and method of operating same|
|US5179934||Feb 14, 1991||Jan 19, 1993||Olympus Optical Co., Ltd.||Endoscope|
|US5203319||Feb 8, 1991||Apr 20, 1993||Welch Allyn, Inc.||Fluid controlled biased bending neck|
|US5531686||Dec 23, 1994||Jul 2, 1996||Ep Technologies, Inc.||Catheter steering mechanism|
|US5591195||Oct 30, 1995||Jan 7, 1997||Taheri; Syde||Apparatus and method for engrafting a blood vessel|
|US6162171 *||Dec 7, 1998||Dec 19, 2000||Wan Sing Ng||Robotic endoscope and an autonomous pipe robot for performing endoscopic procedures|
|EP0788807A1||Feb 4, 1997||Aug 13, 1997||Cordis Corporation||Controlled flexible catheter|
|EP0790066A2||Feb 17, 1992||Aug 20, 1997||Ingemar H. Lundquist||Steerable catheter|
|EP0900575A1||Sep 4, 1998||Mar 10, 1999||Cordis Webster, Inc.||Steerable deflectable catheter having improved flexibility|
|EP0904796A2||Sep 4, 1998||Mar 31, 1999||Cordis Webster, Inc.||Omni-directional steerable catheter|
|FR2659397A1||Title not available|
|WO1995018311A1||Dec 29, 1993||Jul 6, 1995||John D Wentz||Flexible positioning appendage|
|WO1996035877A1||May 7, 1996||Nov 14, 1996||Ati Alternative Tech Innovatio||Fluid actuator|
|WO1997026936A1||Jan 28, 1997||Jul 31, 1997||Endogad Res Pty Ltd||Directional catheter|
|WO1998031944A1||Jan 16, 1998||Jul 23, 1998||Yadama Rathnakar||Flexible shaft|
|WO1999022798A1||Oct 7, 1998||May 14, 1999||Neurovasx Inc||Sub-microcatheter|
|1||Dario et al.; A micro robotic system for colonoscopy; Proceedings of the 1997 IEEE; pp 1567-1572.|
|2||Dario et al.; A miniature steerable end-effector for application in an integrated system for computer-assisted arthroscopy; Proceedings of the 1997 IEEE; pp 1573-1579.|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US7957790 *||Jan 21, 2005||Jun 7, 2011||Siemens Aktiengesellschaft||Catheter|
|US8083879||Nov 22, 2006||Dec 27, 2011||Intuitive Surgical Operations, Inc.||Non-metallic, multi-strand control cable for steerable instruments|
|US8182418||Feb 25, 2008||May 22, 2012||Intuitive Surgical Operations, Inc.||Systems and methods for articulating an elongate body|
|US8361090||Feb 7, 2008||Jan 29, 2013||Intuitive Surgical Operations, Inc.||Apparatus and method for endoscopic colectomy|
|US8517923||May 19, 2004||Aug 27, 2013||Intuitive Surgical Operations, Inc.||Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities|
|US8568299||May 18, 2007||Oct 29, 2013||Intuitive Surgical Operations, Inc.||Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope|
|US8608647||Apr 24, 2012||Dec 17, 2013||Intuitive Surgical Operations, Inc.||Systems and methods for articulating an elongate body|
|US8696694||Dec 28, 2012||Apr 15, 2014||Intuitive Surgical Operations, Inc.||Apparatus and method for endoscopic colectomy|
|US8708955||Jun 2, 2009||Apr 29, 2014||Loma Vista Medical, Inc.||Inflatable medical devices|
|US8721530||Jul 11, 2011||May 13, 2014||Intuitive Surgical Operations, Inc.||Tendon-driven endoscope and methods of use|
|US8827894||Oct 27, 2011||Sep 9, 2014||Intuitive Surgical Operations, Inc.||Steerable endoscope and improved method of insertion|
|US8834354||May 13, 2005||Sep 16, 2014||Intuitive Surgical Operations, Inc.||Steerable endoscope and improved method of insertion|
|US8845622||Apr 2, 2010||Sep 30, 2014||Universite Pierre Et Marie Curie (Paris 6)||Surgical instrument|
|US8882657||Dec 28, 2006||Nov 11, 2014||Intuitive Surgical Operations, Inc.||Instrument having radio frequency identification systems and methods for use|
|US8888688||Nov 12, 2004||Nov 18, 2014||Intuitive Surgical Operations, Inc.||Connector device for a controllable instrument|
|US8961433 *||Jan 6, 2011||Feb 24, 2015||The University Of Western Ontario||Catheter and system for controlling same|
|US8961499||Apr 2, 2010||Feb 24, 2015||Universite Pierre Et Marie Curie (Paris 6)||Surgical instrument|
|US8974375||Jun 24, 2010||Mar 10, 2015||Imperial Innovations Ltd.||Joint arrangement|
|US9138132||Jan 6, 2014||Sep 22, 2015||Intuitive Surgical Operations, Inc.||Steerable endoscope and improved method of insertion|
|US9186049 *||Oct 25, 2012||Nov 17, 2015||Choon Kee Lee||Extensible and guidable apparatus|
|US9186488||Jun 2, 2009||Nov 17, 2015||Loma Vista Medical, Inc.||Method of making inflatable medical devices|
|US20030167007 *||Dec 20, 2002||Sep 4, 2003||Amir Belson||Apparatus and method for spectroscopic examination of the colon|
|US20050154258 *||Dec 20, 2004||Jul 14, 2005||Tartaglia Joseph M.||Endoscope with adjacently positioned guiding apparatus|
|US20050154261 *||Dec 20, 2004||Jul 14, 2005||Ohline Robert M.||Tendon-driven endoscope and methods of insertion|
|US20050187467 *||Jan 21, 2005||Aug 25, 2005||Martin Kleen||Catheter|
|US20070055102 *||Aug 29, 2006||Mar 8, 2007||Yasuo Hirata||Endoscope apparatus|
|US20080051704 *||Aug 28, 2006||Feb 28, 2008||Patel Rajnikant V||Catheter and system for using same|
|US20080243064 *||Feb 15, 2008||Oct 2, 2008||Hansen Medical, Inc.||Support structure for robotic medical instrument|
|US20080262480 *||Feb 15, 2008||Oct 23, 2008||Stahler Gregory J||Instrument assembly for robotic instrument system|
|US20080262513 *||Feb 15, 2008||Oct 23, 2008||Hansen Medical, Inc.||Instrument driver having independently rotatable carriages|
|US20090301643 *||Jun 2, 2009||Dec 10, 2009||Loma Vista Medical, Inc.||Inflatable medical devices|
|US20100099949 *||Jul 30, 2009||Apr 22, 2010||Alexander Quillin Tilson||Biological navigation device|
|US20100113875 *||Mar 19, 2008||May 6, 2010||Iucf-Hyu (Industry-University Cooperation Foundation Hanyang University)||Endoscope and movement control system of the same|
|US20110060186 *||Mar 10, 2011||Alexander Quillin Tilson||Biological navigation device|
|US20110301615 *||Jan 6, 2011||Dec 8, 2011||Patel Rajnikant V||Catheter and system for using same|
|US20120165609 *||Jun 28, 2012||Liu li sheng||Bending device|
|US20130158355 *||Dec 16, 2011||Jun 20, 2013||Pioneer Medical Instrument Co., Ltd.||Two-way endoscope steering mechanism and four-way endoscope steering mechanism|
|US20140118515 *||Oct 25, 2012||May 1, 2014||Choon Kee Lee||Extensible and Guidable Apparatus|
|CN102652050B *||Dec 14, 2010||Sep 9, 2015||费斯托股份有限两合公司||可利用流体运行的操纵器|
|WO2013184192A3 *||Mar 12, 2013||Jul 9, 2015||Massachusetts Institute Of Technology||Continuum style manipulator actuated with phase change media|
|U.S. Classification||600/141, 600/142, 600/144, 604/95.03, 600/152|
|International Classification||G02B23/24, A61B1/00, B25J9/14, F15B11/20, A61M25/01, F15B15/10, A61B1/005, B25J18/06|
|Cooperative Classification||A61B1/0053, F15B15/103, B25J9/142, A61M25/0105, F15B11/20, B25J18/06|
|European Classification||F15B11/20, A61M25/01C, B25J18/06, B25J9/14B, F15B15/10B, A61B1/005B4B|
|Jan 13, 2003||AS||Assignment|
|Sep 16, 2008||FPAY||Fee payment|
Year of fee payment: 4
|Sep 17, 2012||FPAY||Fee payment|
Year of fee payment: 8