|Publication number||US7815646 B2|
|Application number||US 11/759,036|
|Publication date||Oct 19, 2010|
|Priority date||Jun 6, 2007|
|Also published as||CA2633219A1, CA2633219C, DE602008005955D1, EP2005905A1, EP2005905B1, US7927340, US20080306487, US20090287219|
|Publication number||11759036, 759036, US 7815646 B2, US 7815646B2, US-B2-7815646, US7815646 B2, US7815646B2|
|Original Assignee||Karl Storz Gmbh & Co. Kg|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (49), Non-Patent Citations (1), Referenced by (24), Classifications (6), Legal Events (3)|
|External Links: USPTO, USPTO Assignment, Espacenet|
The invention relates to a drill guide and method of providing a drill guide.
Stable healing of a tendon graft to an adjacent bone is often important in tendon or ligament reconstruction. Successful incorporation of the graft is typically dependent on two factors. First, the graft should be fixed in such a way as to maximize the contact area between the graft and the bone, thereby providing the greatest amount of surface area for graft incorporation. Second, the graft fixation should be stable, minimizing the amount of motion between graft and bone. This can minimize the amount of weak fibrous tissue that forms at the bone-graft interface and maximize the degree to which a more stable bone-soft tissue interface develops at the point of bone-graft contact.
More particularly, graft fixation techniques for bone to tendon graft healing often affects the successful incorporation of the graft. One graft fixation technique is the use of an interference screw, which typically improves the pullout strength of tendon grafts. In addition, better tunnel location, tunnel compaction, tighter graft/tunnel fit, improved graft preparation/suturing techniques, and the use of longer, biodegradable screws usually further contribute to increase the pullout strengths.
However, the interference screw itself on one side of the graft can limit the bone/graft contact to a portion of the graft'circumferential area. Some studies suggest stable bony ingrowth of the graft into the surrounding bone occurs at the outer rim of the bone tunnel. With the interference screw, this ingrowth may be limited to the side of the graft that is in direct contact with bone; the other half of the graft contacts the screw and hence is not available for bony ingrowth. Thus, it is possible that there is little or no bony ingrowth where the interference screw intervenes between the tendon graft and the host bone.
In addition, spinning of the tendon graft during insertion of the interference screw may be a problem that is difficult to control once it has begun. This “tendon spin” can damage the graft and result in impingement and less-than-ideal graft positioning, possibly affecting the clinical results.
Furthermore, the benefits of tunnel and graft preparation may be negated if poor technique is used in positioning the interference screw, in which case the screw may become loose or pulled out from the bone. Therefore, positioning of the screw, such as the distance from the bone tunnel and angle of placement, may greatly affect pullout values and can undo the benefits of a properly prepared bone tunnel and/or graft.
What is desired, therefore, is a tool and method for reducing tendon spinning. Another desire is a tool and method for increasing bony ingrowth. A further desire is a tool and method for properly positioning the interference screw and reducing the dependence on the user'technique.
It is therefore an object of the invention to provide a tool and method for reducing tendon spin when securing the tendon to the bone.
Another object is a tool and method for increasing bony ingrowth to promote better attachment of the tendon to the bone.
A further object is a tool and method for properly positioning the interference screw.
Yet another object is a tool and method for reducing the dependence of tendon attachment to the surgeon'technique.
These and other objects of the invention are achieved by a drill guide for placing a fixation device hole proximate to a bone tunnel in a bone, where the drill guide includes a foot for placement in the bone tunnel in the bone and a leg extending from the foot and having a recess. A locator is placed within the recess and, in a retracted position, the locator is inside the leg. The locator is also hingedly connected to the leg such that, in an unretracted position, the locator rotates and extends outwardly from the recess for locating a fixation device hole.
In some embodiments, the recess has a depth large enough so that, in the retracted position, the locator is placed entirely within the recess and the locator includes an orifice through which a guide wire is placed for drilling the fixation device hole. In other embodiments, the leg extends angularly from the foot so that the fixation device hole is drilled angularly as well as downwardly toward the bone tunnel.
In further embodiments, the drill guide has a knob for controlling the locator, which in turn varies a distance between a proposed fixation device hole and the bone tunnel. In some of these embodiments, a shaft is pivotably connected to the locator on one end of the shaft and connected to the knob at the other end of the shaft so that the shaft communicates movement of the knob to the locator.
In other embodiments, an adapter is connected to the shaft and the knob is threadedly engaged with the adapter, wherein rotation of the knob causes the adapter to translate, and therefore the shaft to also translate, in an axial direction. The translation of the shaft causes the locator to rotate about the pivotable connection between the locator and the leg. In this effort, a distance between a height of the locator in an unretracted position is based upon a rotation of the knob. Also, in an unretracted position, the locator extends toward the foot. In some embodiments, the foot includes a notch for receiving the guide wire.
In another embodiment, the drill guide includes a foot for placement in the bone tunnel in the bone, a leg extending from the foot and having a recess, and a locator placed within the recess such that, in a retracted position, the locator is inside the leg. The locator is also hingedly connected to the leg in a first location such that, in an unretracted position, the locator rotates and extends outwardly from the recess for locating the fixation device hole. At the same end as the connection to the leg, the locator is hingedly connected to a shaft in a second location, wherein movement of the shaft away from the foot transfers tensile forces to the locator via the second location and causes the locator to rotate about the first location to the unretracted position, and wherein movement of the shaft toward the foot transfers compressive forces to the locator and causes the locator to rotate about the first location to the retracted position.
In some embodiments, the drill guide has a knob in communication with the locator for controlling the locator to vary a distance between a proposed fixation device hole and the bone tunnel.
In another aspect of the invention, a method for providing the drill guide includes the steps of providing a foot for placement in the bone tunnel in the bone, extending a leg from the foot, placing a recess in the leg, and placing a locator within the recess of the leg for defining a retracted position. The method also hingedly connects the locator to the leg such that, in an unretracted position, the locator rotates and extends outwardly from the recess toward the proposed fixation device hole.
In some embodiments, the method angularly extends the leg from the foot. In other embodiments, the method controls the locator for varying a distance between the fixation device hole and the bone tunnel.
In further embodiments, the method pivotably connects the locator with a shaft for controlling the shaft, which in turn varies a distance between the fixation device hole and the bone tunnel. In some of these embodiments, a threaded knob is connected to the shaft for controlling the locator. In further embodiments, the method determines a number of revolutions of the knob based on the distance between the fixation device hole and the bone tunnel.
In another embodiment, the method pivotably connects the locator to the leg such that translation of the shaft
In an axial direction causes the locator to rotate about the pivotable connection with the leg.
As shown in
As shown more particularly in
As shown, threads 62 are engaged with adapter 64 and adapter 64 is connected to shaft 72 such that rotation of knob 60 causes a translation of adapter 64 and a translation of adapter 64 in turn causes axial movement of shaft 72.
As shown in
When adapter 64 moves axially relative to knob 60, shaft 72 also moves axially relative to knob 60 because shaft 72 is affixed or pinned to adapter 64 via pin 71. In other embodiments, pin 71 is replaced with rivet, fastener, or the like.
Knob 60 is held in place via cross pin 66, which secures knob 60 and housing 68 together and inhibits axial movement between knob 60 and housing 68 but permits rotational movement between knob 60 and housing 68. In some embodiments, cross pin 66 is replaced by any structure that secures housing 68 to knob 60 but permits rotational movement of knob 60 relative to housing 68, such as bearings, a snap ring, or a bushing.
As shown, lower channel 76 is a bored hole through adapter 64 and through hole through sloped section 42, where the bored hole and through hole align with one another. In some embodiments, lower channel 76 is not the bored hole shown in adapter 64 but instead extends all the way through, or is a through hole, which is similar to upper channel 77. All that is required of lower channel 76 is that is has a length long enough to accommodate shaft 72. As shown, upper channel 77 is a through hole penetrating each of adapter 64 and leg 50, where the through holes align with one another.
The operation of drill guide 10 is for the purpose of raising locator 70 from recess 44 to a fully extended position where guide wire 75 (see
As shown in
As stated above, the user rotates knob 60 so that adapter 64 and therefore shaft 72 move axially, where the axial movement of shaft 72 causes locator 70 to rotate about location B, where such rotation results in locator 70 extending outwardly from recess 44 toward the fully unretracted position.
As shown in
As shown in
The distance between fixation device hole 24 and bone tunnel 21, represented in
To this end, a relationship between a number of rotations of knob 60 and height H of locator 70 is known. The relationship involves threads 62 of knob 60, length of shaft 72, placement of hinged connection A, placement of hinged connection B, and angle of sloped section 42. During the manufacture of drill guide 10, all of these factors in the relationship will be known. Therefore, the distance H will be known for any given rotation of knob 60.
More specifically, in some embodiments, a ratio of rotation of knob 60 to rotation of locator 70 is 18:1. Therefore, for every 18 degrees of rotation of knob 60, locator 70 is rotated 1 degree about location A in an outwardly direction from recess 44.
In some of the above embodiments, the total length (indicated as TL in
In further embodiments, a full rotation of knob 60 means shaft 72 translates approximately 0.100 inches. As shown, the total axial movement of shaft is approximately 0.075 inches, which means knob 60 rotates approximately 270 degrees.
In other embodiments, a lateral distance between locations A and B is approximately 0.133 inches, which means for every approximate 0.0023 inch of axial movement of shaft 72, locator 70 is rotated approximately 1 degree. In a preferred embodiment, locator 70 rotates a total of approximately 27 degrees between fully extended and fully retracted positions. Multiplying 0.0023×27 degrees=0.062 inches, which represents the approximate axial movement of locator 70.
The difference between 0.075 and 0.062 inches (0.013 inches) represents the standard of deviation (or slop or measurement error) in a lateral direction due to the stack up from knob 60 to location B. This is a reason for the approximate 27 degree rotation of locator 70 when approximately 15 degrees is all that is needed, where 15 degrees is the approximate angular relation of sloped section 42 relative to foot 30. The approximate 27 degree rotation is to compensate for the approximate 0.013 inch slop, where the over-rotation of locator 70 ensures that the fully retracted and fully extended positions are met. Under ideal circumstances, there would not be any 0.013 inch measurement error in the lateral direction and, therefore, movement in a lateral direction would be the approximate 0.062 inch axial travel of locator 70 and locator would not need to rotate beyond 15 degrees.
In further embodiments, to reduce knob rotation, the ratio is reduced to 15:1 or 12:1. In yet other embodiments, the ratio is 10:1. In embodiments where fine tuning is preferred, whereby locator 70 is rotated in fractions of degrees and H is measured in tenths of inches or millimeters, the ratio is increased to between 20:1 to 30:1, such as 25:1
Another way to reduce knob rotation would be to reduce pitch of threads 62, 65 to, for example, 8 threads per inch. The result would be a reduced knob rotation of approximately ½ turn or approximately 180 degrees. Conversely, increasing pitch would achieve the fine tuning stated above
In some embodiments, the distance H is fixed where locator 70 is in a fully retracted position or a fully unretracted position, where there would not be any positions in between. There would be a mechanical stop on knob 60 letting the user know when to stop rotating knob 60, where rotation reaching this point means locator 70 has extended fully from recess 44.
In other embodiments, the user of drill guide 10 wishes to vary the distance H to a position between the fully retracted and fully unretracted positions. Because the relationship between revolutions of knob 60 and locator 70, the distance H is known. Hence, a user desiring a particular distance H would know how many revolutions are needed and rotate knob 60 to those revolutions. Vice versa, a person rotating knob 60 would know after so many turns the distance H, the desired distance between the fully retracted and unretracted positions, is achieved and then stop rotating knob 60.
In some embodiments, while turning knob 60, the distance H is always known due to a read out of H on a display. Therefore, the user will know when to stop rotating knob 60. In some of these embodiments, the read out or display simply measures the rotations of knob 60 and calculates the relative distance of locator 70 to bone tunnel 21, typically on centers.
The fineness of threads 62 or how close the threads are to one another affects the axial translation of shaft 72. The finer the threads, the more slowly the axial translation and, hence, more revolutions of knob 60 are needed to translate shaft 72 than a coarsely threaded knob. Additionally, the finer the threads, the more accurate or exact H may be set by the user, particularly if H is measured to the tenths of an inch, hundredths of an inch, and the like.
Once the desired H is achieved and locator 70 is in the unretracted position (as stated above in the alternative embodiment, this does not necessarily mean the fully unretracted position), guide wire 75 is inserted into upper channel 77 through adapter 64, is passed through leg 50, and through hole 73 of locator 70 toward bone 22. See
As shown, fixation device hole may be a blind hole, meaning the user cannot visually determine or has reduced visual contact with the end of guide wire 75, and therefore has difficulty determining when fixation device hole 24 is complete or when bone 22 has been penetrated completely through.
In some embodiments, guide wire 75 continues penetrating bone 22 until guide wire 75 comes in contact with foot 30, and more particularly channel 32 and notch 33 of foot 30. Channel 32 receives guide wire 75 and reduces the likelihood of guide wire 75 being skewed or missing foot 30 in a lateral direction. In addition, channel 32 directs guide wire 75 toward notch 33, where in some embodiments a sensor is placed at notch 33 for sensing contact with guide wire 75. Once the sensor senses guide wire 75, a signal is sent to a receiver proximate to the user for indicating to the user that guide wire 75 is in contact with notch 33 and/or channel 32 and therefore has penetrated through bone 22. In yet other embodiments, the sensor is sensitive to metal, which is the material of guide wire 75. In some of these embodiments, the sensor visually detects guide wire 75 making contact with bone 22. In other embodiments, the invention envisions other means for informing the user that guide wire 75 has passed through bone and that fixation device hole 24 is complete.
In another aspect of the invention,
Method 100 also includes hingedly connecting 112 the locator to the leg for permitting the locator to pivot in and out of the recess from the retracted to the unretracted positions, the unretracted position being where the locator rotates and extends outwardly from the recess.
Method 100 also has the step of controlling 116 the locator for varying a distance between the proposed fixation device hole and the bone tunnel. In some embodiments, this step includes pivotably connecting 118 the locator with a shaft that is placed within the leg, connecting 122 a threaded knob to the shaft on the opposite side as the locator, where rotation of the knob causes the locator to pivot out of and/or into the recess.
In further embodiments, controlling the locator also includes determining 124 a number of revolutions of the knob based upon the distance between the proposed fixation device hole and the bone tunnel. In other embodiments, this includes translating 126 the shaft in an axial direction and rotating the locator about the hinged, or pivotable, connection with the leg.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2547571 *||Jun 2, 1950||Apr 3, 1951||Zimmer Mfg Company||Hip fracture drill guide|
|US4669473||Sep 6, 1985||Jun 2, 1987||Acufex Microsurgical, Inc.||Surgical fastener|
|US4672957||Sep 26, 1984||Jun 16, 1987||South African Inventions Development Corporation||Surgical device|
|US4722331||Sep 3, 1985||Feb 2, 1988||Fox James M||Orthopaedic tool guide|
|US4733654||May 29, 1986||Mar 29, 1988||Marino James F||Intramedullar nailing assembly|
|US4739751||Oct 3, 1986||Apr 26, 1988||Temple University||Apparatus and method for reconstructive surgery|
|US4781182||Oct 3, 1986||Nov 1, 1988||Purnell Mark L||Apparatus and method for use in performing a surgical operation|
|US4901711||Dec 27, 1988||Feb 20, 1990||Marlowe Goble E||Drill guide|
|US4911153||Feb 4, 1988||Mar 27, 1990||Biomet, Inc.||Orthopedic surgical instrument|
|US4920958||Jun 27, 1988||May 1, 1990||Minnesota Mining And Manufacturing Company||Drill guide assembly|
|US4950271||Feb 6, 1989||Aug 21, 1990||Regents Of The University Of Minnesota||Ligament graft apparatus and method|
|US5026376 *||Jul 13, 1990||Jun 25, 1991||Greenberg Alex M||Surgical drill guide and retractor|
|US5112337||Feb 5, 1991||May 12, 1992||Depuy Du Pont Orthopaedics||Variable angle, selective length tibial drill guide|
|US5154720||Feb 19, 1992||Oct 13, 1992||Linvatec Corporation||Surgical drill guide|
|US5163940||Mar 4, 1991||Nov 17, 1992||American Cyanamid Company||Surgical drill guide for tibia|
|US5234434||Aug 17, 1992||Aug 10, 1993||Marlowe Goble E||Mutliple guide sleeve drill guide|
|US5300077||Feb 23, 1993||Apr 5, 1994||Arthrotek||Method and instruments for ACL reconstruction|
|US5314429||Nov 29, 1991||May 24, 1994||Marlowe Goble E||Method for forming a tunnel intersecting a straight cruciate ligament tunnel|
|US5320626||Feb 19, 1992||Jun 14, 1994||Arthrex Inc.||Endoscopic drill guide|
|US5324295||Apr 24, 1992||Jun 28, 1994||Shapiro Michael R||Drill guide for surgical pins|
|US5330468||Oct 12, 1993||Jul 19, 1994||Burkhart Stephen S||Drill guide device for arthroscopic surgery|
|US5350383||Feb 18, 1993||Sep 27, 1994||Arthrex, Inc.||Adjustable drill guide with interchangeable marking hooks|
|US5385567 *||Sep 7, 1990||Jan 31, 1995||Goble; E. Marlowe||Sight barrel arthroscopic instrument|
|US5454816||May 25, 1994||Oct 3, 1995||Howmedica International Inc.||Femoral cutting guide|
|US5458602||Jan 11, 1994||Oct 17, 1995||Mitek Surgical Products, Inc.||Surgical drill guide|
|US5514144 *||Dec 20, 1993||May 7, 1996||Bolton; Carl W.||Drill guide device for the arthroscopic anatomic placement of a straight tibio-femoral bone tunnel for ACL reconstruction|
|US5562664||Feb 15, 1995||Oct 8, 1996||Arthrex Inc.||Drill guide with target PCL-oriented marking hook|
|US5584839 *||Dec 12, 1994||Dec 17, 1996||Gieringer; Robert E.||Intraarticular drill guide and arthroscopic methods|
|US5601550 *||Oct 25, 1994||Feb 11, 1997||Esser; Rene D.||Pelvic pin guide system for insertion of pins into iliac bone|
|US5601566||Feb 22, 1994||Feb 11, 1997||Osteonics Corp.||Method and apparatus for the alignment of a femoral knee prosthesis|
|US5613971||Aug 11, 1995||Mar 25, 1997||Depuy Inc.||Ratcheting tibial and femoral guide|
|US5643273||Feb 17, 1995||Jul 1, 1997||Clark; Ron||ACL bone tunnel projection drill guide and method for its use|
|US5669915 *||Mar 22, 1996||Sep 23, 1997||Aesculap Ag||Drilling jig for surgical drilling tools|
|US5681320||Mar 26, 1996||Oct 28, 1997||Mcguire; David A.||Bone-cutting guide|
|US5683400||Jun 7, 1995||Nov 4, 1997||Mcguire; David A.||Graft preparation table|
|US5688284||Sep 20, 1996||Nov 18, 1997||Medicinelodge, Inc.||Variable angle drill guide and ligament fixation method|
|US5891150||Dec 4, 1996||Apr 6, 1999||Chan; Kwan-Ho||Apparatus and method for fixing a ligament in a bone tunnel|
|US5968050||Dec 5, 1997||Oct 19, 1999||Smith & Nephew, Inc.||Positioning a tibial tunnel|
|US6019767||Jun 23, 1995||Feb 1, 2000||Arthrotek||Tibial guide|
|US6120511||Nov 18, 1997||Sep 19, 2000||Chan; Kwan-Ho||Drill guide assembly and method for producing a bone tunnel|
|US6210415||Feb 18, 2000||Apr 3, 2001||Lab Engineering & Manufacturing, Inc.||Surgical drill guide|
|US6254604||Apr 27, 1999||Jul 3, 2001||Arthrotek, Inc.||Tibial guide|
|US6254605||Nov 27, 2000||Jul 3, 2001||Stephen M. Howell||Tibial guide|
|US6342057 *||Apr 28, 2000||Jan 29, 2002||Synthes (Usa)||Remotely aligned surgical drill guide|
|US6547795 *||Aug 13, 2001||Apr 15, 2003||Depuy Acromed, Inc.||Surgical guide system for stabilization of the spine|
|US7144424||Apr 14, 2003||Dec 5, 2006||Karl Storz Gmbh & Co. Kg||Method and apparatus for reconstructing a ligament|
|US20040199170 *||Apr 23, 2004||Oct 7, 2004||Endius Incorporated||Surgical instrument for moving vertebrae|
|US20050137704 *||Nov 4, 2004||Jun 23, 2005||Steenlage Eric S.||Method and apparatus for reconstructing a ligament|
|US20050177171 *||Aug 29, 2003||Aug 11, 2005||Merrick Wetzler||Surgical drill guide|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US8282647 *||Oct 9, 2012||Tyco Healthcare Group Lp||Femoral guide for ACL repair having adjustable offset|
|US8303589 *||Jun 23, 2009||Nov 6, 2012||Extremity Medical Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US8313487||Nov 20, 2012||Extremity Medical Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US8328806||Dec 11, 2012||Extremity Medical, Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US8343199||Sep 2, 2010||Jan 1, 2013||Extremity Medical, Llc||Intramedullary fixation screw, a fixation system, and method of fixation of the subtalar joint|
|US8579892||Jul 2, 2008||Nov 12, 2013||Tsunami Medtech, Llc||Medical system and method of use|
|US8771273 *||Dec 17, 2008||Jul 8, 2014||Karl Storz Gmbh & Co. Kg||Surgical drill for providing holes at an angle|
|US8771274||Nov 16, 2011||Jul 8, 2014||Karl Storz Gmbh & Co. Kg||Surgical drill for providing holes at an angle|
|US8858549||Mar 14, 2012||Oct 14, 2014||Tsunami Medtech, Llc||Medical instruments and techniques for treating pulmonary disorders|
|US8900223||Nov 8, 2010||Dec 2, 2014||Tsunami Medtech, Llc||Tissue ablation systems and methods of use|
|US8900274||Oct 5, 2012||Dec 2, 2014||Extremity Medical Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US8920453||Dec 7, 2012||Dec 30, 2014||Extremity Medical, Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US8920476||Oct 5, 2012||Dec 30, 2014||Extremity Medical, Llc||Fixation system, an intramedullary fixation assembly and method of use|
|US9017329||Jun 1, 2010||Apr 28, 2015||Extremity Medical, Llc||Intramedullary fixation assembly and method of use|
|US9044282||Feb 11, 2010||Jun 2, 2015||Extremity Medical Llc||Intraosseous intramedullary fixation assembly and method of use|
|US9113944||Nov 19, 2012||Aug 25, 2015||Tsunami Medtech, Llc||Method for performing lung volume reduction|
|US9204889||Sep 12, 2011||Dec 8, 2015||Tsunami Medtech, Llc||Medical instrument and method of use|
|US9289220||Sep 7, 2011||Mar 22, 2016||Extremity Medical Llc||Intramedullary fixation assembly and method of use|
|US9364271 *||Jan 19, 2015||Jun 14, 2016||Extremity Medical Llc||Intraosseous intramedullary fixation assembly and method of use|
|US20090157081 *||Dec 17, 2008||Jun 18, 2009||Bradley Michael Homan||Surgical Drill For Providing Holes At An Angle|
|US20100049200 *||Aug 27, 2009||Feb 25, 2010||Tyco Healthcare Group Lp||Femoral guide for acl repair having adjustable offset|
|US20100121324 *||Jun 23, 2009||May 13, 2010||Jeff Tyber||Fixation system, an intramedullary fixation assembly and method of use|
|US20110077628 *||Aug 13, 2010||Mar 31, 2011||Tsunami Medtech, Llc||Medical system and method of use|
|US20150133936 *||Jan 19, 2015||May 14, 2015||Extremity Medical L.L.C.||Intraosseous intramedullary fixation assembly and method of use|
|International Classification||A61B17/58, A61B17/60, A61F2/00|
|Jun 11, 2007||AS||Assignment|
Owner name: KARL STORZ ENDOVISION, INC., MASSACHUSETTS
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HART, RICKEY;REEL/FRAME:019409/0369
Effective date: 20070531
|May 20, 2009||AS||Assignment|
Owner name: KARL STORZ GMBH & CO. KG, GERMANY
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:KARL STORZ ENDOVISION, INC.;REEL/FRAME:022711/0881
Effective date: 20090425
|Mar 26, 2014||FPAY||Fee payment|
Year of fee payment: 4