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Publication numberUS8083721 B2
Publication typeGrant
Application numberUS 12/362,004
Publication dateDec 27, 2011
Filing dateJan 29, 2009
Priority dateJan 29, 2009
Also published asCA2751538A1, EP2391411A1, EP2391411A4, US8523821, US20100191185, US20120136301, WO2010088146A1
Publication number12362004, 362004, US 8083721 B2, US 8083721B2, US-B2-8083721, US8083721 B2, US8083721B2
InventorsStephen C. Miller
Original AssigneeNavilyst Medical, Inc.
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Power injection valve
US 8083721 B2
Abstract
A device for transferring fluids between an internal structure in a living body and an exterior thereof, comprises a housing including a pressure activated lumen extending to a distal end opening to a power injection lumen that extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body and a pressure activated valve extending across the pressure activated lumen and controlling fluid flow therethrough, the pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level in combination with a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port.
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Claims(9)
1. A device for transferring fluids between an internal structure in a living body and an exterior thereof, comprising:
a housing including a pressure activated lumen and a power injection lumen, wherein the power injection lumen extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body;
a pressure activated valve configured to fluidly connect the pressure activated lumen to the power injection lumen and controlling fluid flow therebetween, the pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level; and
a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port.
2. The device according to claim 1, wherein, when in the first position, the proximal port seals the proximal end of the pressure activated lumen and, when in the second position, the proximal port seals the proximal end of the pressure injection lumen.
3. The device according to claim 2, wherein, when in a third position, the proximal port seals the proximal ends of both the pressure activated and power injection lumens.
4. The device according to claim 1, wherein the pressure activated valve includes a slitted flexible membrane.
5. The device according to claim 4, wherein the slitted flexible membrane is formed of silicone.
6. The device according to claim 1, wherein the pressure activated valve opens to permit fluid flow therethrough from the power injection lumen into the pressure activated lumen at a second threshold level higher than the first threshold level.
7. The device according to claim 6, wherein the pressure activated valve is constructed so that the second threshold level is higher than a pressure differential to which the valve will be subjected during power injection via the power injection lumen.
8. The device according to claim 1, wherein the proximal port is rotatably coupled to a proximal portion of the housing for rotation between the first and second positions.
9. The device according to claim 1, wherein the distal port is adapted to couple to a catheter.
Description
BACKGROUND

Procedures requiring the use of peripherally inserted central catheters (“PICC”) often employ pressure activated valves to seal these catheters when not in use. Such pressure activated valves are designed to remain closed during normal pressure fluctuations between uses to prevent leakage and backflow which may lead to occlusions and/or infections. However, these valves have often been unsuitable for the injection of fluids at high pressures or volumes.

SUMMARY OF THE INVENTION

The present invention is directed to a device for transferring fluids between an internal structure in a living body and an exterior thereof, comprises a housing including a pressure activated lumen extending to a distal end opening to a power injection lumen that extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body and a pressure activated valve extending across the pressure activated lumen and controlling fluid flow therethrough, the pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level in combination with a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port.

The present invention is further directed to a method for transferring fluids between a target internal structure of a living body and an exterior of the body, the method comprising connecting to a proximal end of a fluid conduit extending into the body to the target structure a distal port of a housing opening to a power injection lumen thereof, the housing including a pressure activated lumen extending to a distal end opening to the power injection lumen with a pressure activated valve opening to permit fluid flow therethrough into the power injection lumen when a fluid pressure differential thereacross is at least a first predetermined threshold level and remaining sealed when the fluid pressure differential thereacross is less than the first threshold level and moving a proximal port of the housing to a first position in which the proximal port is fluidly coupled to the power injection lumen in combination with supplying a first fluid to the proximal port at a power injection pressure greater than the first threshold level, moving the proximal port of the housing to a first position in which the proximal port is fluidly coupled to the pressure activated lumen and supplying a second fluid to the proximal port at a pressure greater than the first threshold level and less than the power injection pressure.

BRIEF DESCRIPTION OF THE DRAWINGS

The accompanying drawing illustrates the design of the present invention wherein:

FIG. 1 shows a first view of an apparatus according to a first embodiment of the present invention;

FIG. 2 shows an exploded view of the device of FIG. 1;

FIG. 3 shows an internal view of the device of FIG. 1;

FIG. 4 shows a side view of the device of FIG. 1;

FIG. 5 shows a bottom view of the device of FIG. 1;

FIG. 6 shows a top view of the device of FIG. 1;

FIG. 7 shows a perspective view of the device of FIG. 1 in a position permitting flow through a pressure activated valve; and

FIG. 8 shows a perspective view of the device of FIG. 1 in a normal flow position.

DETAILED DESCRIPTION

The present invention, which may be further understood with reference to the following description and the appended drawings, relates to a system and method for high pressure and high volume injection without damaging a pressure activated valve. In particular, the present invention relates to the selective engagement for high pressure and high volume injection of separate lumens within a device employed in conjunction with a catheter (e.g., a PICC catheter) with at least one of the lumens employing a pressure activated valve.

Presently available pressure activated valves are generally unable to sustain the high pressures and flow rates associated with power injection (e.g., of contrast media). An exemplary embodiment of the present invention seeks to alleviate this problem by incorporating with a pressure activated valve a bypass feature allowing power injection without damaging the pressure activated valve.

As shown in FIGS. 1-8, a port 100 according to a first embodiment of the invention includes two passages which may be selectively engaged to select either power injection or standard infusion/withdrawal of fluids. The port 100 comprises a base 110 and a cover 120 joined together, for example, via any known means such as bonding, welding, friction fit, etc. Protruding distally from the port 100 is an elongated tubular body 105 with a lumen 115 extending therethrough and into the base 110, as will be described in greater detail below. It is noted that the term proximal as referred to herein refers to a direction approaching a user or point of user access to the device while distal refers to a direction toward an interior of the body of the patient.

The tubular body 105 is provided with a barbed fitting comprising a series of ridged portions 106 designed to frictionally engage a catheter disposed thereover. Specifically, the ridged portions 106 are formed with a diameter sized to frictionally engage inner walls of a catheter, thereby firmly securing the catheter to the port 100. Accordingly, to mate to the port 100, a catheter is guided over the tubular body 105 to a proximal-most position and frictionally retained thereon. In an alternate embodiment, the tubular body 105 may be insert molded on the catheter, as those skilled in the art will understand.

As shown in the exploded view of FIG. 2, a silicone disk 130 is provided in the port 100, in engagement with a correspondingly sized recess 131 in the base 110 which opens to the lumen 115. The silicone disk 130 effectively regulates the pressure and flow of fluids passing therethrough the port 100. As would be understood by those skilled in the art, the disk 130 may be formed in any desired configuration to obtain desired flow configurations. For example, the disk 130 and a slot or slots therethrough may be formed as shown for any of slitted membranes disclosed in U.S. patent application Ser. No. 10/768,571 entitled “Pressure Activated Safety Valve With Anti-Adherent Coating” filed on Jan. 29, 2004 to Weaver, et al. (the '571 app.); U.S. application Ser. No. 10/768,565 entitled “Pressure Activated Safety Valve With High Flow Slit” filed on even day herewith naming Karla Weaver and Paul DiCarlo as inventors, and U.S. application Ser. No. 10/768,629 entitled “Stacked Membrane For Pressure Actuated Valve” filed on even day herewith naming Karla Weaver and Paul DiCarlo as inventors, and U.S. application Ser. No. 10/768,855 entitled “Pressure Actuated Safety Valve With Spiral Flow Membrane” filed on even day herewith naming Paul DiCarlo and Karla Weaver as inventors, and U.S. application Ser. No. 10/768,479 entitled “Dual Well Port Device” filed on even day herewith naming Katie Daly, Kristian DiMatteo and Eric Houde as inventors. The entire disclosures of each of these applications are hereby incorporated by reference in this application. The silicone disk 130 is held in place over the recess 131 via a disk retainer 135 which engages a periphery thereof. When the cover 120 is mounted to the base 110, a portion of the cover 120 engages the disk retainer 135 applying pressure against the disk 130 to hold the disk 130 against a periphery of the recess 131 and prevent the silicone disk 130 from being moved therefrom.

A rotating luer 150 engages a proximal end of the base 110 at a proximal end of the port 100, as further shown in FIG. 3. The rotating luer 150 includes a lumen 155 extending therethrough from a proximal end 151 to a distal end 152 and at least two tabs 160 extending therefrom about a circumference of an end plate 158 of the luer 150 which preferably forms a substantially continuous surface with the portion of the port 100 (i.e., proximal ends of the base 110 and the cover 120 regardless of a rotational orientation of the luer 150. The tabs 160 indicate an alignment of the lumen 155 in relation to the two lumens 115 and 125 of the port 100, as will be described in greater detail below. The luer 150 also includes a disk-shaped mating projection 156 which is received within a correspondingly shaped and sized slot 154 to rotatably secure the luer 150 to the base 110.

Two O-rings 140 are provided between the rotating luer 150 and the upper and lower body portions 120, 110 to provide a fluid seal therebetween. However, those skilled in the art will understand that any number of O-rings may be provided in the device and these O-rings may vary in thickness and size to obtain the desired seal. The O-rings may exhibit elastomeric properties and may, in an exemplary embodiment, be received in recesses formed on a proximal faces of the base 110 and the cover 120 around proximal openings to the lumens 115, 125, respectively.

As shown in FIG. 3, when in a pressure activated position, the lumen 155 of the luer 150 is aligned with the lumen 125 of the cover 120 which opens to the disk 130. As would be understood by those skilled in the art, when a pressure differential between the lumen 125 and the lumen 115 exceeds a predetermined threshold, edges of the slit(s) in the disk 130 are moved apart from one another and fluid will flow through the disk 130 into the lumen 115 to a catheter attached thereto. When the pressure differential remains below the predetermined threshold, the disk 130 remains sealed preventing fluid flow from the lumen 115 to the lumen 125.

In order to configure the port 100 in the pressure activated position as also shown in FIGS. 6 and 7, a user of the port 100 rotates the luer 150 until the tabs 160 are aligned with corresponding projections (e.g., projections 161) on the port distal body of the port 100 (i.e., the base 110 and/or the cover 120) to an indicated pressure activated position. Specifically, the proximal portion of the port 100 may be labeled to indicate the locations of the lumens 115 and 125, as shown in FIGS. 5 and 6. A physician may then rotate the proximal portion of the port 100 to align the tabs 160 with the projections 161. Rotating the proximal portion of the port 100 in either a clockwise or counter-clockwise direction until the lumen 155 aligns with the desired lumen of the port 100 engages the desired one of the lumens 125 and 115. It is further noted that, when the tabs 160 are not aligned with the projections 161, the port 100 is in an off position with both of the lumens 115 and 125 sealed to prevent the flow of fluid into or out of the proximal portion of the device.

Once the pressure activated valve has been selected, the flow of fluid through the port 100 is guided through the pressure activated valve, as detailed above, with fluid entering the port 100 through an externally attached fluid source via an attachment means shown at the proximal end 151 of the rotating luer 150. The fluid flows through the lumen 155 and into the lumen 125 and, when the pressure differential exceeds the predetermined threshold level, past the silicone disk 130 into the lumen 115 via the recess 131. The fluid is passes through the lumen 115 toward the elongated tubular body 105 as flow toward the proximal end of the lumen 115 is prevented by the fluid-tight seal formed by the distal face of the rotating luer 150 which covers the proximal opening to the lumen 115 when the pressure activated valve has been selected. The fluid flows out of the distal opening of the elongated tubular body 105 to a targeted site in the body via a catheter or other device attached to the tubular body portion 105 as would be understood by those skilled in the art.

Alternatively, if the “<5 mL/s” marker is selected, as shown in FIGS. 5 and 8, the lumen 155 is connected directly to the lumen 115 located inside the base 110 of the port 100. An external high pressure or high volume fluid source may then be attached to a proximal end of the port 100 so that high pressure and/or high volume fluid (e.g., at flow rates and pressures suitable for the power injection of contrast media) supplied to the port 100 passes directly through the lumen 115 to the distal opening in the body 105 and into the catheter without passing through the disk 130. It is further noted that the diameter of the lumen 155 may be substantially similar to the diameter of the lumen 115 to allow for an undeterred flow of fluid therethrough.

The present invention has been described with respect to particular designs and embodiments. However, those skilled in the art will understand that the described exemplary embodiments of the present invention may be altered without departing from the spirit or scope of the invention. For example, the port 100 may be altered in geometry, with the diameters of the either of the lumens 115, 125 and 155 increased or decreased to accommodate the requirements of a patient or procedure for which they are intended. Furthermore, a design may be incorporated with each of the lumens 115 and 125 identified by a different color or pattern of colors, eliminating the need for written markings on the outer body of the port 100.

It is to be understood that these embodiments have been described in an exemplary manner and are not intended to limit the scope of the invention which is intended to cover all modifications and variations of this invention that come within the scope of the appended claims and their equivalents. The specifications are, therefore, to be regarded in an illustrative rather than a restrictive sense.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2720881Jun 8, 1953Oct 18, 1955Leslie Jones JohnClosure
US3113586Sep 17, 1962Dec 10, 1963Physio Control Company IncArtificial heart valve
US3159175Dec 12, 1961Dec 1, 1964Delman CoFluid check valve unit
US3159176Dec 7, 1962Dec 1, 1964Vernay LaboratoriesCheck-relief valve
US3477438Apr 17, 1967Nov 11, 1969Dwight L AllenCatheter having one-way inflations valve
US3514438Jun 6, 1969May 26, 1970Amicon CorpAntithrombogenic materials
US3525357Nov 18, 1968Aug 25, 1970Waters Co ThePump valve apparatus
US3621557Jun 6, 1969Nov 23, 1971Rex Chainbelt IncInsert for sandwich panels and method of installation
US3669323Dec 12, 1969Jun 13, 1972American Can CoOne-way valve insert for collapsible dispensing containers
US3673612Aug 28, 1970Jul 4, 1972Massachusetts Inst TechnologyNon-thrombogenic materials and methods for their preparation
US3674183Feb 1, 1971Jul 4, 1972Venable Catherine MDispensing device
US3811466Apr 6, 1972May 21, 1974Ohringer JSlit diaphragm valve
US3955594Feb 25, 1974May 11, 1976Raymond International Inc.Pressure operated valve systems
US4000740 *Aug 15, 1975Jan 4, 1977Baxter Travenol Laboratories, Inc.Injection site
US4072146Sep 8, 1976Feb 7, 1978Howes Randolph MVenous catheter device
US4142525Nov 17, 1977Mar 6, 1979The Kendall CompanySyringe assembly
US4143853Jul 14, 1977Mar 13, 1979Metatech CorporationValve for use with a catheter or the like
US4405316Apr 3, 1978Sep 20, 1983Baxter Travenol Laboratories, Inc.Injection site with check valve inlet
US4434810May 24, 1982Mar 6, 1984Vernay Laboratories, Inc.Bi-directional pressure relief valve
US4447237May 7, 1982May 8, 1984Dow Corning CorporationValving slit construction and cooperating assembly for penetrating the same
US4468224Jan 28, 1982Aug 28, 1984Advanced Cardiovascular Systems, Inc.System and method for catheter placement in blood vessels of a human patient
US4543087Nov 14, 1983Sep 24, 1985Quinton Instrument CompanyDouble lumen catheter tip
US4552553Jan 30, 1984Nov 12, 1985Pudenz-Schulte Medical Research Corp.Flow control valve
US4610276 *Sep 29, 1982Sep 9, 1986Nypro Inc.Directional flow control
US4610665Jan 3, 1984Sep 9, 1986Terumo Kabushiki KaishaMedical instrument
US4616768Jun 1, 1984Oct 14, 1986Lingner & Fischer GmbhDischarge barrier for collapsible tubes
US4673393Dec 24, 1985Jun 16, 1987Terumo Kabushiki KaishaMedical instrument
US4681572Jul 27, 1983Jul 21, 1987Hollister IncorporatedFemale urinary incontinence device
US4692146Oct 24, 1985Sep 8, 1987Cormed, Inc.Multiple vascular access port
US4790832Jun 6, 1986Dec 13, 1988Icu Medical, Inc.System for administering medication nasally to a patient
US4798594Sep 21, 1987Jan 17, 1989Cordis CorporationMedical instrument valve
US4801297Jun 1, 1984Jan 31, 1989Edward Weck IncorporatedCatheter having slit tip
US4944726Nov 3, 1988Jul 31, 1990Applied Vascular DevicesDevice for power injection of fluids
US4946448Oct 23, 1989Aug 7, 1990Kendall Mcgaw Laboratories, Inc.Check valve for use with intravenous pump
US5000745Nov 18, 1988Mar 19, 1991Edward Weck IncorporatedHemostatis valve
US5009391Oct 31, 1990Apr 23, 1991The Kendall CompanyValve assembly
US5030210Feb 8, 1988Jul 9, 1991Becton, Dickinson And CompanyCatheter valve assembly
US5084015May 15, 1989Jan 28, 1992Terumo Kabushiki KaishaCatheter assembly of the hypodermic embedment type
US5098405Jan 31, 1991Mar 24, 1992Becton, Dickinson And CompanyApparatus and method for a side port cathether adapter with a one piece integral combination valve
US5125893Apr 16, 1990Jun 30, 1992Dryden Gale ESuction catheter with wall lumen for irrigation
US5147332May 17, 1991Sep 15, 1992C.R. Bard, Inc.Multi-valve catheter for improved reliability
US5149327Aug 15, 1990Sep 22, 1992Terumo Kabushiki KaishaMedical valve, catheter with valve, and catheter assembly
US5167638Jul 9, 1991Dec 1, 1992C. R. Bard, Inc.Subcutaneous multiple-access port
US5169393Oct 15, 1991Dec 8, 1992Robert MooreheadTwo-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5176652Apr 26, 1991Jan 5, 1993Cordis CorporationHemostasis valve
US5201722Sep 4, 1990Apr 13, 1993Moorehead Robert HTwo-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5205834Jun 24, 1992Apr 27, 1993Moorehead H RobertTwo-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5249598Aug 3, 1992Oct 5, 1993Vernay Laboratories, Inc.Bi-directional vent and overpressure relief valve
US5254086Jul 31, 1992Oct 19, 1993Ballard Medical ProductsMedical lavage apparatus and methods
US5330424Jun 24, 1993Jul 19, 1994Ballard Medical ProductsMedical lavage apparatus and methods
US5336203May 28, 1993Aug 9, 1994Abbott LaboratoriesLow profile gastrostomy device with dome
US5360407Aug 29, 1991Nov 1, 1994C. R. Bard, Inc.Implantable dual access port with tactile ridge for position sensing
US5370624Sep 14, 1993Dec 6, 1994Becton Dickinson And CompanyCatheter with deactivatable side port
US5396925Dec 16, 1993Mar 14, 1995Abbott LaboratoriesAnti-free flow valve, enabling fluid flow as a function of pressure and selectively opened to enable free flow
US5399168Jul 29, 1992Mar 21, 1995C. R. Bard, Inc.Implantable plural fluid cavity port
US5401255Jul 20, 1993Mar 28, 1995Baxter International Inc.Multi-functional valve with unitary valving member and improved safety
US5405340Feb 7, 1994Apr 11, 1995Abbott LaboratoriesThreaded securing apparatus for flow connectors
US5411491May 28, 1993May 2, 1995Abbott LaboratoriesLow profile gastrostomy device with one-way cross-slit valve
US5453097Aug 15, 1994Sep 26, 1995Paradis; Joseph R.Control of fluid flow
US5454784Jun 10, 1994Oct 3, 1995Zimmer, Inc.For connection to a fluid source and a surgical site
US5469805Jan 7, 1994Nov 28, 1995Keystone International Holdings Corp.High visibility valve position indicator
US5470305Apr 19, 1993Nov 28, 1995Stryker CorporationIrrigation handpiece with built in pulsing pump
US5484420Dec 7, 1993Jan 16, 1996Wilson-Cook Medical Inc.Retention bolsters for percutaneous catheters
US5542923Jun 6, 1995Aug 6, 1996Michigan Transtech CorporationImplantable access devices
US5554136Feb 27, 1995Sep 10, 1996Luther Medical Products, Inc.Dual lumen infusion/aspiration catheter
US5562618Jan 21, 1994Oct 8, 1996Sims Deltec, Inc.Portal assembly and catheter connector
US5571093Sep 21, 1994Nov 5, 1996Cruz; CosmeMultiple-lumen catheter
US5575769May 30, 1995Nov 19, 1996Vaillancourt; Vincent L.Cannula for a slit septum and a lock arrangement therefore
US5624395Oct 20, 1995Apr 29, 1997Cv Dynamics, Inc.Urinary catheter having palpitatable valve and balloon and method for making same
US5637099Jun 9, 1994Jun 10, 1997Durdin; Daniel J.Needle handling apparatus and methods
US5667500May 25, 1995Sep 16, 1997Ballard Medical ProductsMedical lavage apparatus and methods
US5707357Feb 22, 1996Jan 13, 1998C V Dynamics, Inc.Balloon catheter having palpitatable discharge valve and retention collar
US5743873Sep 16, 1996Apr 28, 1998Sims Deltec, Inc.Methods for using catheter connectors and portals, and methods of assembly
US5743884Jun 22, 1995Apr 28, 1998Hasson; Harrith M.Sealing structure for medical instrument
US5743894Jun 7, 1995Apr 28, 1998Sherwood Medical CompanySpike port with integrated two way valve access
US5752938Jun 7, 1995May 19, 1998Richard-Allan Medical Industries, Inc.Seal for surgical instruments
US5803078May 26, 1995Sep 8, 1998Brauner; Mark E.Methods and apparatus for intrapulmonary therapy and drug administration
US5807349Mar 10, 1997Sep 15, 1998United States Surgical CorporationCatheter having valve mechanism
US5843044Jun 16, 1997Dec 1, 1998Catheter InnovationsMedical fluid flow control assembly
US5853397Dec 12, 1994Dec 29, 1998Migada, Inc.Medical infusion apparatus including safety valve
US5865308Oct 29, 1996Feb 2, 1999Baxter International Inc.System, method and device for controllably releasing a product
US5944698Oct 14, 1997Aug 31, 1999Ultradent Products, Inc.Adjustable flow syringe
US5984902Mar 16, 1998Nov 16, 1999Catheter Innovations, IncOutdwelling slit valve and variable control for controlling opening and closing the slit
US6033393Dec 31, 1996Mar 7, 2000Johnson & Johnson Medical, Inc.Method and apparatus for overpressure protection of a catheter
US6045734May 18, 1999Apr 4, 2000Becton Dickinson And CompanyProcess of making a catheter
US6050934Feb 25, 1998Apr 18, 2000Cv Dynamics, Inc.Urinary catheter having palpitatable discharge valve with protective shoulders
US6056717Feb 2, 1998May 2, 2000Vasca, Inc.Implantable vascular device
US6062244Aug 13, 1998May 16, 2000Aci MedicalFluidic connector
US6092551May 19, 1998Jul 25, 2000Chesebrough-Pond's Usa Co., Division Of Conopco, Inc.Duckbill valve
US6120483Mar 19, 1999Sep 19, 2000Boston Scientific CorporationMedical fluid infusion and aspiration
US6152909Feb 19, 1998Nov 28, 2000Percusurge, Inc.Aspiration system and method
US6210366May 26, 1999Apr 3, 2001Sanfilippo, Ii Dominic JosephVascular access kit
US6227200Jul 20, 1999May 8, 2001Ballard Medical ProductsRespiratory suction catheter apparatus
US6270489Aug 25, 2000Aug 7, 2001Catheter Innovations, Inc.Anti-clotting methods and apparatus for indwelling catheter tubes
US6306124Feb 24, 2000Oct 23, 2001Micro Therapeutics, Inc.Microcatheter
US6364861Sep 17, 1998Apr 2, 2002Porex Medical Products, Inc.Multi-valve injection/aspiration manifold
US6364867Jul 1, 1999Apr 2, 2002Catheter Innovations, Inc.Anti-clotting methods and apparatus for indwelling catheter tubes
US6375637Aug 27, 1999Apr 23, 2002Gore Enterprise Holdings, Inc.Catheter balloon having a controlled failure mechanism
US6436077Aug 7, 2000Aug 20, 2002Boston Scientific CorporationMedical fluid infusion and aspiration
US6442415Aug 12, 1999Aug 27, 2002Magnetic Moments, L.L.C.Contrast-enhanced coronary artery and coronary artery bypass graft imaging using an aortic root catheter injection with either magnetic resonance angiography or computed tomographic angiography
US7758541 *Aug 17, 2004Jul 20, 2010Boston Scientific Scimed, Inc.Targeted drug delivery device and method
USD357735Aug 3, 1993Apr 25, 1995I-Flow CorporationValve for filling an IV solution bag
Non-Patent Citations
Reference
1Asch, "Venous access: options, approaches and issues," Can Assoc. Radiol J., vol. 52, No. 3 pp. 153-164 (2001).
2Carlson et al., "Safety considerations in the power injection of contrast media via central venous catheters during computered tomogrphic examinations," Invest. Radiol., vol. 27, No. 5, p. 337-340 (1992).
3Chahous et al., "Randomized comparison of coronary angiography using 4F catheters: 4F manual versus 'Acisted' power injection technique," Catheter Cardiovasc. Interv., vol. 53, No. 2, pp. 221-224 (2001).
4Chahous et al., "Randomized comparison of coronary angiography using 4F catheters: 4F manual versus ‘Acisted’ power injection technique," Catheter Cardiovasc. Interv., vol. 53, No. 2, pp. 221-224 (2001).
5Herts et al., "Power injection of contrast media using central venous catheters: feasibility, safety, and efficacy," AJR Am. J. Roentgenol., vol. 176, No. 2, pp. 447-453 (2001).
6Herts et al., "Power injection of intravenous contrast material through central venous catheters for CT: in vitro evaluation," Radiology, vol. 200, No. 3, pp. 731-735 (1996).
7Kaste et al., "Safe use of powr injectors with central and peripheral venous access devices for pediatrict CT," Pediatr. Radiol., vol. 26, No. 8, pp. 449-501 (1996).
8PCT International Search Report-International application No. PCT/US2010/021740, dated Mar. 18, 2010, 2-Pgs.
9PCT International Search Report—International application No. PCT/US2010/021740, dated Mar. 18, 2010, 2-Pgs.
10Rivitz et al., "Power injection of peripherally inserted central catheters," J. Vasc. Interv. Radiol., vol. 8, No. 5, pp. 857-863 (1997).
11Rogalla et al., Safe and easy power injection of contrast material through a central line, Eur. Radiol., vol. 8, No. 1, pp. 148-149 (1998).
12Roth et al., "Influence of radiographic contrast media viscosity to flow through coronary angiographic catheters," Cathet. Cardiovasc. Diagn., vol. 22, No. 4, pp. 290-294 (1991).
13Saito et al., "Diagnostic brachial coronary arteriography using a power-assisted injector and 4 French catheters with new shamps," J. Invasive Cardiol., vol. 9, No. 7, pp. 461-468 (1997).
14Walsh et al., "Effect of contrast agent viscosity and injection flow velocity on bolus injection pressures for peripheral venous injection in first-pass myocardial perfusion studies," Technol. Health Care, vol. 10, No. 1, pp. 57-63 (2002).
15Williamson et al., "Assessing the adequacy of peripherally inserted central catheters for power injection of intravenous contrast agents for CT," J. Comput. Assist. Tomogr., vol. 25, No. 6, pp. 932-937 (2001).
Classifications
U.S. Classification604/167.03, 604/167.05, 604/43, 604/118, 604/248, 604/186
International ClassificationA61M5/00, A61M3/00, A61M5/178
Cooperative ClassificationA61M2039/242, A61M39/24, A61M2039/027, A61M39/22
European ClassificationA61M39/22, A61M39/24
Legal Events
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Sep 30, 2013ASAssignment
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May 23, 2012ASAssignment
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Apr 17, 2009ASAssignment
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MILLER, STEPHEN C.;REEL/FRAME:22573/718
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