|Publication number||USRE39200 E1|
|Application number||US 08/785,445|
|Publication date||Jul 18, 2006|
|Filing date||Jan 17, 1997|
|Priority date||May 12, 1989|
|Publication number||08785445, 785445, US RE39200 E1, US RE39200E1, US-E1-RE39200, USRE39200 E1, USRE39200E1|
|Original Assignee||Boston Scientific Scimed, Inc.|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (41), Classifications (13), Legal Events (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This is a Continuation Reissue Application of Ser. No. 08/120,212, filed Sep. 10, 1993, now Reissue No. 35,775, which is a Reissue of Application of Ser. No. 07/518,163, filed May 3, 1990, now U.S. Pat. No. 5,047,028.
1. Field of the Invention
This invention relates to methods employing balloon tubes in medical practice. More particularly, the invention concerns a method of using a balloon tube for inducing thrombosis in blood vessels located directly under the surface of a cavity in the body which is difficult to reach.
2. Description of the Prior Art
Balloon tubes are known from T. V. Taylor and J. M. M. Neilson's article “Currents and Clots” —an approach to the problem of acute variceal bleeding”. Br. J. Surg. Vol. 68 (1981) 692-696. It is known how to stop bleeding of vessels located directly under the surface of a difficult to reach body cavity, through thrombosis by introducing a deflated balloon tube into the body cavity and then inflating it by applying a fluid at the correct position. The balloon tube from the previous proposal is furnished with electrodes on its outer surface. These electrodes are supplied with a voltage across an electrically conductive wire. An electrode, possibly placed on the patient's back, can serve as an oppositely charged electrode. The electric current which arises through the application of voltage between the two electrodes induces thrombosis and therefore acts to stop the bleeding of the vessels.
Such thrombosis in bleeding vessels is indicated especially for oesophageal varices but could also be involved in bleeding in other body cavities.
The balloon tube which is known from the above-named article has not been able to assert itself in practice, since the resistance between the electrode and the surface of the body cavity is not defined.
The aim of the invention is to further develop the balloon tube as it is already known, so that it suffices for the demands of practical use.
Through this invention this problem can be solved by the fact that the fluid which serves to inflate the balloon is capable of carrying in an electric current and the membrane wall of the balloon is semi-permeable for the fluid.
The wire, which is to be led through the tube, should preferably be made of platinum.
Normal saline solution can be used as the fluid. Other electrically conductive fluids, such as electrode gel, can be used. The fluid can also serve as a conductor of medication.
The invention is explained by the following description and drawings in which:
Throughout the following detailed description, the same reference numerals refer to the same elements in all figures.
The balloon tube which has been used corresponds in its appearance at first glance to a normal Sengstaken-Tube. It consists of a tube 10 and a balloon 12 located near the end of tube 10. Tube 10 is furnished with openings 14 in the area in which the tube 10 is led through balloon 12. A conductive wire 16 is led through tube 10. Preferably, the conductive wire is made from platinum.
As an example, to stop bleedings of the oesophageal varices, the balloon tube is introduced into the oesophagus, whereby balloon 12 is deflated. When the desired place has been reached, a conductive fluid, for example, normal saline solution, is introduced into the tube 10. The fluid enters balloon 12 through the openings 14 in tube 10 and fills it. The balloon membrane walls 18 are of a semipermeable nature. Therefore, a small amount of the conducting fluid flows through the balloon walls 18. The balloon wall 18 offers no significant electrical resistance.
A counter electrode 20 with a large surface is applied to the chest area of the patient in the case of thrombosis of oesophageal varices.
By applying a source of voltage between the platinum wire 16 and the counter electrode 20 with opposite charge, a current arises between these two which induces the desired thrombosis through the choice of a suitable voltage difference between them.
The special wire 16 is not absolutely necessary, but rather the conductive fluid found in the tube also can be used as an electric conductor. Tube 10 is not semi-permeable and therefore offers considerable electric resistance.
Instead of a normal saline solution, a substance such as electrode gel, for example, also can be used as a conducting fluid.
The balloon tube suggested here can further be used for example for the treatment of post-operative rebleedings after urethra operations or by lower intestinal bleedings or also by nasopharyngeal bleedings.
A further method is to add medications to the conducting fluid which induce blood-stanching over an iontophoretic tissue diffusion.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US578611||Apr 24, 1798||Mar 9, 1897||Thirds to louis f|
|US600290||Aug 24, 1897||Mar 8, 1898||Therapeutic electrode|
|US791730||Jun 1, 1903||Jun 6, 1905||Johan Jakob Stanger||Electrical mouth-bath.|
|US866180||Jun 13, 1907||Sep 17, 1907||Cutler Taylor Ball||Combined applicator and dilator.|
|US873021||Aug 2, 1907||Dec 10, 1907||Harlow R Cool||Electrotherapeutic syringe.|
|US2123980||Jul 21, 1934||Jul 19, 1938||G M Basford Company||Therapeutic treatment|
|US3411507||Apr 1, 1964||Nov 19, 1968||Medtronic Inc||Method of gastrointestinal stimulation with electrical pulses|
|US3618601||Oct 16, 1969||Nov 9, 1971||Richardson Thatcher W||Iontophoresis unit|
|US3716054||Aug 11, 1970||Feb 13, 1973||Porter W||Apparatus for applying medication to teeth and body tissue|
|US3991755||Jan 2, 1975||Nov 16, 1976||Medicon, Inc.||Iontophoresis apparatus for applying local anesthetics|
|US4250878||Nov 22, 1978||Feb 17, 1981||Motion Control, Inc.||Non-invasive chemical species delivery apparatus and method|
|US4309989||Aug 14, 1978||Jan 12, 1982||The Curators Of The University Of Missouri||Topical application of medication by ultrasound with coupling agent|
|US4383529||Nov 3, 1980||May 17, 1983||Wescor, Inc.||Iontophoretic electrode device, method and gel insert|
|US4405311||Dec 8, 1980||Sep 20, 1983||Greatbatch Enterprises, Inc.||Method and apparatus for direct electrical injection of gold ions into tissue such as bone|
|US4411648||Jun 11, 1981||Oct 25, 1983||Board Of Regents, The University Of Texas System||Iontophoretic catheter device|
|US4506680||Mar 17, 1983||Mar 26, 1985||Medtronic, Inc.||Drug dispensing body implantable lead|
|US4522205||Sep 3, 1981||Jun 11, 1985||The University Court Of The University Of Edinburgh||Therapeutic device and method of inducing thrombosis in a blood vessel|
|US4569673||Jan 12, 1984||Feb 11, 1986||Battelle Development Corporation||Bacterial barrier for indwelling catheters and other medical devices|
|US4574807||Mar 2, 1984||Mar 11, 1986||Carl Hewson||Method and apparatus for pacing the heart employing external and internal electrodes|
|US4577642||Feb 27, 1985||Mar 25, 1986||Medtronic, Inc.||Drug dispensing body implantable lead employing molecular sieves and methods of fabrication|
|US4717381||May 13, 1986||Jan 5, 1988||Kos Medical Technologies, Ltd.||Hydrodynamically propelled catheter|
|US4752285||Mar 19, 1986||Jun 21, 1988||The University Of Utah Research Foundation||Methods and apparatus for iontophoresis application of medicaments|
|US4767402||Jul 8, 1986||Aug 30, 1988||Massachusetts Institute Of Technology||Ultrasound enhancement of transdermal drug delivery|
|US4776349||Oct 3, 1986||Oct 11, 1988||Basem Nashef||Tubular device for the treatment of hollow organs with electric current|
|US4877031||Jul 22, 1988||Oct 31, 1989||Advanced Cardiovascular Systems, Inc.||Steerable perfusion dilatation catheter|
|US4892519||Dec 3, 1987||Jan 9, 1990||Advanced Cardiovascular Systems, Inc.||Steerable perfusion dilatation catheter|
|US4915685||Jun 19, 1987||Apr 10, 1990||Petelenz Tomasz J||Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange|
|US4944745||Feb 29, 1988||Jul 31, 1990||Scimed Life Systems, Inc.||Perfusion balloon catheter|
|US4960133 *||Nov 21, 1988||Oct 2, 1990||Brunswick Manufacturing Co., Inc.||Esophageal electrode|
|US4979948||Apr 13, 1989||Dec 25, 1990||Purdue Research Foundation||Method and apparatus for thermally destroying a layer of an organ|
|US4994033||May 25, 1989||Feb 19, 1991||Schneider (Usa) Inc.||Intravascular drug delivery dilatation catheter|
|US5135477||Feb 10, 1988||Aug 4, 1992||Medtronic, Inc.||Iontophoretic drug delivery|
|DE3516830A1||May 10, 1985||Nov 13, 1986||Hubmann Max||Katheter|
|DE3809815A1||Mar 23, 1988||Oct 12, 1989||Peter Zimmer||Internal electrode for introduction in a body cavity|
|EP0119296A1||Aug 30, 1983||Sep 26, 1984||Baylor College of Medicine||An apparatus for intra-aortic balloon monitoring and leak detection|
|EP0438078A2||Jan 9, 1991||Jul 24, 1991||Cino Rossi||Iontophoresis device|
|SU322202A1||Title not available|
|SU843999A1||Title not available|
|SU1069826A1||Title not available|
|SU1069827A1||Title not available|
|WO1991019529A1||Jun 14, 1991||Dec 26, 1991||Cortrak Medical, Inc.||Drug delivery apparatus and method|
|International Classification||A61F2/958, A61B18/14, A61B18/00|
|Cooperative Classification||A61B2018/00494, A61B18/1492, A61M25/10, A61B2018/00214, A61B2018/00065, A61B2018/0022, A61B2018/00488|
|European Classification||A61B18/14V, A61M25/10|
|May 11, 2005||AS||Assignment|
Owner name: BOSTON SCIENTIFIC SCIMED, INC., MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:016553/0601
Effective date: 20041222