|Publication number||USRE39651 E1|
|Application number||US 09/895,623|
|Publication date||May 22, 2007|
|Filing date||Jun 27, 2001|
|Priority date||Nov 4, 1996|
|Also published as||US5916242|
|Publication number||09895623, 895623, US RE39651 E1, US RE39651E1, US-E1-RE39651, USRE39651 E1, USRE39651E1|
|Inventors||George R. Schwartz|
|Original Assignee||Schwartz George R|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (10), Non-Patent Citations (1), Referenced by (1), Classifications (11), Legal Events (4)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This application claims the benefit of U.S. Provisional Application No. 60/030,030 filed Nov. 4, 1996.
1. Field of the Invention
This invention relates to apparatus and method for cooling the brain, and in particular to apparatus and method for inducing hypothermia throughout the tissues of the brain.
2. Description Relative to the Prior Art
It is well known in the medical art that depriving the brain of oxygen for even a short period of time results in irreversible damage to the brain tissue. Such deprivation occurs during stroke, respiratory arrest, cardiac arrest, trauma and other severe bodily disturbances that slow or otherwise hinder the flow of oxygenated blood to the brain. However, it is also known that lowering the temperature of the brain (hypothermia) slows its metabolic activity, and reduces the chance of tissue damage when the oxygen supply is diminished.
At present, operative neurosurgery and cardiac surgery is done in many cases using hypothermia for the specific purposes of maintaining cerebral and cardiac function. In an operating room, this requires use of a cooling module in conjunction with heart/lung bypass techniques by which the patient's blood, and resultantly the patient's brain tissue, is cooled. This widespread ability to rapidly lower brain temperature by as little as four or five degrees can make an enormous difference in preservation of function. However, out in the field, when medical emergencies occur, brain cooling must quickly and expeditiously take place without access to the sophisticated equipment available in the hospital operating room. A portable brain cooling apparatus usable in the field is described in U.S. Pat. No. 5,261,399, issued in the names of Klatz et al. For use on an injured or disabled patient, the patent discloses a helmet and back plate containing cavities in which a coolant flows to cool the brain by means of heat conduction through the skull and upper spinal column.
Rather than cooling the brain by the relatively slow heat conduction through the low heat conductivity of the bony skull and hair covering the head, the present invention teaches the use of a light weight, easily applied neck encircling collar in firm contact with the soft tissue of the neck, and particularly in good thermal contact with the carotid arteries traversing the neck. A coolant flowing through channels embedded in the collar rapidly cools the blood flowing through the carotid arteries which branch into blood vessels throughout the brain providing vascular access and attendant rapid internal cooling throughout the brain including its deepest recesses. Placing the collar on the patient's neck is easily and quickly accomplished simultaneously with other emergency medical techniques, such as CPR, which maintain the patient's heart and lung activity.
The collar of the invention contains no metallic parts; the collar, including the coolant channel, may be non-metallized fabric or plastic. This allows X-ray, Cat scan, or MRI procedures to be used while the collar is in place without impairing the effectiveness of the procedure.
In a second embodiment for rapid internal cooling of the brain, a conventional endotracheal tube, inserted into the trachea, is provided with an toroidal bladder surrounding the tube. The toroidal bladder is positioned at the back of the oral cavity, and a coolant flowing through the toroid cools blood vessels in the oral cavity which also traverse the brain, providing cooling of the brain tissue.
The endotracheal tube and the bladder are made from materials including non-metallic fabric or plastic materials, such that these components are compatible with X-ray, MRI or CAT scan procedures.
The coolant flowing through the channels of the collar or the toroidal bladder may be any of the well known liquid or gaseous refrigerants, for example, gaseous CO2, freon, or ice water, pumped through the channels of the collar or toroidal bladder in a manner known in the refrigeration art.
The invention will be described with respect to the drawings, of which:
The invention has been described in detail with particular reference to preferred embodiments thereof, but it will be understood that variations and modifications can be effected within the spirit and scope of the invention. For example, the first embodiment of the invention may be incorporated into a neck support collar used for supporting an injured patient's head.
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|Citing Patent||Filing date||Publication date||Applicant||Title|
|US9320644||Jul 25, 2012||Apr 26, 2016||Neurosave, Inc.||Non-invasive systems, devices, and methods for selective brain cooling|
|International Classification||A61F7/02, A61F7/10, A61F7/00, A61F7/12|
|Cooperative Classification||A61F2007/0009, A61F2007/0056, A61F7/12, A61F7/10|
|European Classification||A61F7/12, A61F7/10|
|Jun 29, 2007||FPAY||Fee payment|
Year of fee payment: 8
|Jun 29, 2007||SULP||Surcharge for late payment|
Year of fee payment: 7
|Feb 20, 2008||AS||Assignment|
Owner name: PEACOCK MYERS, P.C., NEW MEXICO
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SCHWARTZ, GEORGE;REEL/FRAME:020532/0417
Effective date: 20080201
|Dec 9, 2010||FPAY||Fee payment|
Year of fee payment: 12