WO1990013264A1 - Device for preparing bone cement - Google Patents

Device for preparing bone cement Download PDF

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Publication number
WO1990013264A1
WO1990013264A1 PCT/SE1990/000018 SE9000018W WO9013264A1 WO 1990013264 A1 WO1990013264 A1 WO 1990013264A1 SE 9000018 W SE9000018 W SE 9000018W WO 9013264 A1 WO9013264 A1 WO 9013264A1
Authority
WO
WIPO (PCT)
Prior art keywords
agitator
channel
rod
lid
bone cement
Prior art date
Application number
PCT/SE1990/000018
Other languages
French (fr)
Inventor
Staffan Smeds
Sören JONSSON
Jan Thorling
Thomas Nilsson
Original Assignee
Surgitec Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surgitec Ab filed Critical Surgitec Ab
Priority to EP90903630A priority Critical patent/EP0470959B1/en
Priority to DE69022047T priority patent/DE69022047T2/en
Publication of WO1990013264A1 publication Critical patent/WO1990013264A1/en
Priority to NO19914245A priority patent/NO314923B1/en
Priority to KR1019910701507A priority patent/KR0131143B1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8825—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by syringe details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50—Mixing receptacles
    • B01F35/514—Mixing receptacles the mixing receptacle or conduit being transparent or comprising transparent parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7137—Piercing, perforating or melting membranes or closures which seal the compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7173—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7173—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper
    • B01F35/71731—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper using a hopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
    • A61B2017/8838—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means for mixing bone cement or fluid fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30561—Special structural features of bone or joint prostheses not otherwise provided for breakable or frangible
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/4685—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor by means of vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0071—Additional features; Implant or prostheses properties not otherwise provided for breakable or frangible
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/20—Mixing of ingredients for bone cement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B01F23/565—Mixing liquids with solids by introducing liquids in solid material, e.g. to obtain slurries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms

Definitions

  • the present invention relates to an arrangement for the manufacture of bone cement by mixing together its constituent components comprising a mixing cylinder in the form of a tube with a bottom and a lid and inside the mixing cylinder an axially movable agitator in the form of a piston-like agitator disc, which is perforated by channels, through which the components of the bone cement are caused to flow during the mixing procedure and an agitator rod resembling a piston rod operatively connected to the agitator disc and supported in the lid in such a way that it is free to slide.
  • Bone cement is used in hip-joint operations, for example.
  • the object of the present invention is to make available a preparation arrangement for bone cement, which is intended to be disposable and capable of being manufactured efficiently and at a low cost, and which also contributes to meeting the requirements stipulated above in respect of the prepared bone cement.
  • SUBSTITUTESHEET channel which is closed off at the agitator disc in such a way that it is capable of being opened, in that the bottom is executed with a device projecting towards the agitator disc arranged in such a way, when mixing is complete, as to penetrate the membrane at that time, and in that the bottom is so arranged, under the effect of an axial force, as to be displaced like a piston axially in the direction of the lid, in conjunction with which the bone cement flows out through the channel in the agitator rod.
  • FIG. la and lb illustrate schematically in longitudinal section a mixing cylinder with a bottom and an agitator supported in a lid in such a way that it is free to slide, in accordance with a first embodiment of the preparation arrangement in accordance with the invention.
  • Fig. lc illustrates an agitator disc in accordance with the invention viewed from below.
  • Fig. 2 is a longitudinal section through an arrangement in accordance with the aforementioned first embodiment
  • Fig. 3 illustrates in detail the penetration of a sealing membrane.
  • Fig. 4 illustrates how the aforementioned first embodiment of the preparation arrangement in accordance with the present invention is used as a bone cement syringe.
  • Fig. 5 is a longitudinal section through a second embodiment of the preparation arrangement in accordance with the invention.
  • the designation 1 is used in the drawing for a mixing cylinder, and 2 for a bottom which is inserted in a sealing fashion into one end of the mixing cylinder 1.
  • the mixing cylinder 1 is preferably made from a transparent material
  • the bottom 2 which, for reasons which will become clear later, is made from a rubber-like elastic material, is executed with a projecting stud 2a facing towards the inside of the cylinder and has an annular flange-like projection 2b which engages in a corresponding groove la in the inner wall of the mixing cylinder 1.
  • the preparation arrangement in accordance with the invention also includes a lid 3 with an agitator 4 capable of axial movement therein.
  • This comprises a piston-like agitator disc 4a and an agitator rod 4b supported in the lid 3 in such a way that it is free to slide.
  • the lid is sealed against the inner wall of the mixing cylinder 1 and against the agitator rod 4b by means of 'O'-rings 5 and 6.
  • the lid 3 also extiibits an evacuation channel 3a, which, via a line 7, is capable of connection to a vacuum source ' (not shown here), ' and which, when the lid 3 is fitted, discharges into the internal space of the mixing cylinder.
  • the agitator disc 4a is perforated by channels 4al, through which the bone cement components are caused to flow during agitation in order to make this as effective as possible.
  • the agitator rod 4b exhibits in accordance with the invention an axial channel 4bl, which is closed off at the end of the rod 4b which is attached to the agitator disc 4a.
  • the closure consists of a penetrable membrane 4c. This has fractural impressions 4cl, which are illustrated in Fig. lc.
  • a dot screen and the designation 8 are used in Fig. la to indicate a powder, and the designation 9 and a pattern of dashes to indicate a liquid, which are the components of the bone cement and have been introduced into the mixing cylinder 1 via the opening which is intended to be closed off by means of the lid 3. In the interests of clarity, these components are omitted from the other Figures.
  • Fig. 2 The mixing procedure itself is illustrated in Fig. 2. With the help of the agitator rod 4b, the agitator disc 4a is caused to move up and down inside the mixing cylinder 1. This movement is indicated by means of a. bidirectional arrow 10 in Fig. 2. Bidirectional arrows 11 are also used in the same Figure to illustrate how the components 8, 9 are caused in this way to flow through the channels 4al and through a space between the agitator disc 4a and the internal wall of the cylinder 1. Since the cylinder wall is transparent, a person skilled in the art can easily decide when the preparation of the bone cement is complete.
  • the agitator 4 is moved downwards with a deliberate movement, which in Fig. 3 is illustrated by a downward-facing arrow 12, so that the agitator disc 4a cames into contact with the bottom 2. This results in penetration of the membrane 4c by the stud 2a, causing the membrane to rupture along the fractural impressions 4cl, which is illustrated by arrows 13 in Fig. 3.
  • the agitator is then pulled to the position illustrated in Fig. 4.
  • the channel 4bl inside the agitator rod 4b now communicates with the space inside the mixing cylinder l in which the prepared bone cement is present.
  • a syringe mechanism of the kind which is customarily used for the extrusion of sealing compound or similar in the form of a bead.
  • This mechanism is indicated in Fig. 4 on the one hand as a holder part 14 marked as broken lines, in which the mixing cylinder 1 with its bottom 2, lid 3 and agitator 4 are placed, and on the other hand as a compression piston 15 with an associated compression rod 16.
  • the mixing cylinder 1 and lid 3 are manufactured in a single piece- in this case, and the lid part 3, like the embodiment described above, has an evacuation channel 3a and a seal 5 against the agitator rod 4b.
  • the bottom 2 in this case is formed as an outwardly open cup with annular flange-like seals 2b in contact with the inner wall of the mixing cylinder 1.
  • the embodiment in accordance with Fig. 5 has a funnel 19 removably attached to the outer end of the agitator rod 4b and a rod 2Q introduced into the axial channel 4bl of the agitator rod 4b, together with a tubular holder 21 into which the mixing cylinder 1 is introduced.
  • the narrow opening of the funnel 19 is in close contact with the agitator rod 4b, and its purpose is to facilitate the introduction of the bone cement components into the mixing cylinder l, for which purpose the rod 20 must have been pulled from the channel 4bl.
  • the rod 20 is of a length such that, when introduced fully into the channel 4bl, it reaches into the vicinity of the agitator disc 4a and is in this area executed with a seal 20a in contact with the inner wall of the channel 4b.
  • the rod 20 with the seal 20a corresponds in its function to the membrane 4cl described above.
  • the rod 20 is executed with a draw ring 20b or similar.
  • the mixing cylinder 1 and the piston 2 are fixed relative to the holder 21 by means of a removable cotter pin 22.
  • the preparation arrangement in accordance with Fig. 5 is used as follows: The rod 20 is first removed so that the bone cement components can be introduced into the mixing cylinder 1 via the channel 4bl. The funnel 19 is then removed, and the rod 20 is introduced into the channel 4bl. The bone cement components are now mixed together, as previously described in conjunction with Figure 2, when any gases which occur are removed via the channel 3a. During the mixing procedure the arrangement is placed in the holder 21. Once the mixing procedure is complete, the cotter pin 22 is withdrawn from its position, thereby enabling the preparation arrangement to be removed reely from its holder 21 and placed in the syringe mechanism in the manner explained in conjunction with Figure 4. Once the cotter pin 22 has been removed, the piston 2 can be displaced axially under the effect of the compression piston 15. Once the rod 20 has been removed from the channel 4bl, bone cement can be forced out through it for the intended use.

Abstract

The present invention relates to an arrangement for the manufacture of bone cement by mixing together its constituent components comprising a mixing cylinder (1) in the form of a tube with a bottom (2) and a lid (3) and inside the mixing cylinder an axially movable agitator (4). The agitator consists of a piston-like agitator disc (4a), which is perforated by channels (4a1), through which the components of the bone cement are caused to flow during the mixing procedure and an agitator rod (4b) resembling a piston rod operatively connected to the agitator disc (4a) and supported in the lid (3) in such a way that it is free to slide. The invention is characterized in that the agitator rod (4b) has an axial channel (4b1), which is closed off at the agitator disc (4a) in such a way that it is capable of being opened. The bottom (2) is so arranged, under the effect of an axial force, as to be displaced like a piston axially in the direction of the lid (3), in conjunction with which the bone cement flows out through the channel (4b1) after it has been opened.

Description

Device for preparing bone cement.
The present invention relates to an arrangement for the manufacture of bone cement by mixing together its constituent components comprising a mixing cylinder in the form of a tube with a bottom and a lid and inside the mixing cylinder an axially movable agitator in the form of a piston-like agitator disc, which is perforated by channels, through which the components of the bone cement are caused to flow during the mixing procedure and an agitator rod resembling a piston rod operatively connected to the agitator disc and supported in the lid in such a way that it is free to slide.
Bone cement is used in hip-joint operations, for example.
When manufacturing bone cement, for which purpose a component in the form of a powder and a liquid component require to be mixed, it is important that the mixture should be as homogeneous as possible, and that gases which occur during the mixing procedure are removed to the greatest extent possible. Any lack of homogeneity and gas inclusions have the effect of reducing the strength of the bone cement, which can result in a shorter service life for the implanted prosthesis. Furthermore, the gases which occur during manufacture are unhealthy, for which reason steps must be taken to ensure that they do not escape into the operating theatre.
The object of the present invention is to make available a preparation arrangement for bone cement, which is intended to be disposable and capable of being manufactured efficiently and at a low cost, and which also contributes to meeting the requirements stipulated above in respect of the prepared bone cement.
This object is met in that the agitator rod has an axial
SUBSTITUTESHEET channel, which is closed off at the agitator disc in such a way that it is capable of being opened, in that the bottom is executed with a device projecting towards the agitator disc arranged in such a way, when mixing is complete, as to penetrate the membrane at that time, and in that the bottom is so arranged, under the effect of an axial force, as to be displaced like a piston axially in the direction of the lid, in conjunction with which the bone cement flows out through the channel in the agitator rod.
Additional advantages of the invention can be appreciated from the accompanying dependent claims and from the following description with reference to the accompanying drawing, in which Figs. la and lb illustrate schematically in longitudinal section a mixing cylinder with a bottom and an agitator supported in a lid in such a way that it is free to slide, in accordance with a first embodiment of the preparation arrangement in accordance with the invention. Fig. lc illustrates an agitator disc in accordance with the invention viewed from below. Fig. 2 is a longitudinal section through an arrangement in accordance with the aforementioned first embodiment, and Fig. 3 illustrates in detail the penetration of a sealing membrane. Fig. 4 illustrates how the aforementioned first embodiment of the preparation arrangement in accordance with the present invention is used as a bone cement syringe. Fig. 5 is a longitudinal section through a second embodiment of the preparation arrangement in accordance with the invention.
The designation 1 is used in the drawing for a mixing cylinder, and 2 for a bottom which is inserted in a sealing fashion into one end of the mixing cylinder 1. The mixing cylinder 1 is preferably made from a transparent material, and the bottom 2 , which, for reasons which will become clear later, is made from a rubber-like elastic material, is executed with a projecting stud 2a facing towards the inside of the cylinder and has an annular flange-like projection 2b which engages in a corresponding groove la in the inner wall of the mixing cylinder 1.
The preparation arrangement in accordance with the invention also includes a lid 3 with an agitator 4 capable of axial movement therein. This comprises a piston-like agitator disc 4a and an agitator rod 4b supported in the lid 3 in such a way that it is free to slide. The lid is sealed against the inner wall of the mixing cylinder 1 and against the agitator rod 4b by means of 'O'-rings 5 and 6. The lid 3 also extiibits an evacuation channel 3a, which, via a line 7, is capable of connection to a vacuum source' (not shown here),' and which, when the lid 3 is fitted, discharges into the internal space of the mixing cylinder.
The agitator disc 4a is perforated by channels 4al, through which the bone cement components are caused to flow during agitation in order to make this as effective as possible. The agitator rod 4b exhibits in accordance with the invention an axial channel 4bl, which is closed off at the end of the rod 4b which is attached to the agitator disc 4a. The closure consists of a penetrable membrane 4c. This has fractural impressions 4cl, which are illustrated in Fig. lc.
A dot screen and the designation 8, are used in Fig. la to indicate a powder, and the designation 9 and a pattern of dashes to indicate a liquid, which are the components of the bone cement and have been introduced into the mixing cylinder 1 via the opening which is intended to be closed off by means of the lid 3. In the interests of clarity, these components are omitted from the other Figures.
The mixing procedure itself is illustrated in Fig. 2. With the help of the agitator rod 4b, the agitator disc 4a is caused to move up and down inside the mixing cylinder 1. This movement is indicated by means of a. bidirectional arrow 10 in Fig. 2. Bidirectional arrows 11 are also used in the same Figure to illustrate how the components 8, 9 are caused in this way to flow through the channels 4al and through a space between the agitator disc 4a and the internal wall of the cylinder 1. Since the cylinder wall is transparent, a person skilled in the art can easily decide when the preparation of the bone cement is complete.
Once it has been established that the preparation is complete, the agitator 4 is moved downwards with a deliberate movement, which in Fig. 3 is illustrated by a downward-facing arrow 12, so that the agitator disc 4a cames into contact with the bottom 2. This results in penetration of the membrane 4c by the stud 2a, causing the membrane to rupture along the fractural impressions 4cl, which is illustrated by arrows 13 in Fig. 3. The agitator is then pulled to the position illustrated in Fig. 4. The channel 4bl inside the agitator rod 4b now communicates with the space inside the mixing cylinder l in which the prepared bone cement is present.
The preparation arrangement in accordance with the invention is now placed inside a syringe mechanism of the kind which is customarily used for the extrusion of sealing compound or similar in the form of a bead. This mechanism is indicated in Fig. 4 on the one hand as a holder part 14 marked as broken lines, in which the mixing cylinder 1 with its bottom 2, lid 3 and agitator 4 are placed, and on the other hand as a compression piston 15 with an associated compression rod 16.
When the compression piston 15 is caused to press against the bottom 2, which is illustrated by an upward-facing arrow 17, and when the compressive force has reached a sufficiently high level, the annular flange-like projection 2b will, as compression takes place, be forced out of the groove la and will function as a seal against the inner wall of the mixing cylinder 1. The bottom 2 now acts as a piston and forces the bone cement through the penetrated membrane 4c and via the channel 4bl to the outside for its intended use, as shown by an arrow 18. The same reference designations are used in Fig. 5 in respect of details with the same function as, or with an analogous function to the corresponding details in the, earlier Figures. This Figure illustrates the alternative embodiment of the preparation arrangement in the state in which it is supplied for use. The mixing cylinder 1 and lid 3 are manufactured in a single piece- in this case, and the lid part 3, like the embodiment described above, has an evacuation channel 3a and a seal 5 against the agitator rod 4b. The bottom 2 in this case is formed as an outwardly open cup with annular flange-like seals 2b in contact with the inner wall of the mixing cylinder 1.
Unlike the embodiment of an arrangement in accordance with the invention for the manufacture of bone cement described above, the embodiment in accordance with Fig. 5 has a funnel 19 removably attached to the outer end of the agitator rod 4b and a rod 2Q introduced into the axial channel 4bl of the agitator rod 4b, together with a tubular holder 21 into which the mixing cylinder 1 is introduced. The narrow opening of the funnel 19 is in close contact with the agitator rod 4b, and its purpose is to facilitate the introduction of the bone cement components into the mixing cylinder l, for which purpose the rod 20 must have been pulled from the channel 4bl. The rod 20 is of a length such that, when introduced fully into the channel 4bl, it reaches into the vicinity of the agitator disc 4a and is in this area executed with a seal 20a in contact with the inner wall of the channel 4b. The rod 20 with the seal 20a corresponds in its function to the membrane 4cl described above. At its opposite end the rod 20 is executed with a draw ring 20b or similar. The mixing cylinder 1 and the piston 2 are fixed relative to the holder 21 by means of a removable cotter pin 22.
The preparation arrangement in accordance with Fig. 5 is used as follows: The rod 20 is first removed so that the bone cement components can be introduced into the mixing cylinder 1 via the channel 4bl. The funnel 19 is then removed, and the rod 20 is introduced into the channel 4bl. The bone cement components are now mixed together, as previously described in conjunction with Figure 2, when any gases which occur are removed via the channel 3a. During the mixing procedure the arrangement is placed in the holder 21. Once the mixing procedure is complete, the cotter pin 22 is withdrawn from its position, thereby enabling the preparation arrangement to be removed reely from its holder 21 and placed in the syringe mechanism in the manner explained in conjunction with Figure 4. Once the cotter pin 22 has been removed, the piston 2 can be displaced axially under the effect of the compression piston 15. Once the rod 20 has been removed from the channel 4bl, bone cement can be forced out through it for the intended use.

Claims

Patent Claims
1. Arrangement for the manufacture of bone cement by mixing together its constituent components comprising a mixing cylinder (1) in the form of a tube with a bottom (2) and a lid (3) and inside the mixing cylinder an axially movable agitator (4) in the form of a piston-like agitator disc (4a) , which is perforated by channels (4al) , through which the components of the bone cement are caused to flow during the mixing procedure and an agitator rod (4b) resembling a piston rod operatively connected to the agitator disc (4a) and supported in the lid (3) in such a way that it is free to slide, characterized in that the agitator rod (4b) exhibits an axial channel (4bl) , which is closed off#,at the agitator disc (4a), and in that the bottom (2) is so arranged, under the effect of an axial force, as to be displaced like a piston axially in the direction of he lid (3) , in conjunction with which the bone cement flows out through the channel (4bl) after it has been opened.
2. Arrangement in accordance with Patent Claim, 1, characterized in that the closure of the channel (4bl) is achieved with a rod capable of being introduced into the channel, which rod is executed at one end with a seal, which, when in its introduced position in the area around the agitator disc (4a) , is in contact with the inner wall of the channel (4bl) .
Arrangement in accordance with Patent Claim 1, characterized in that the channel (4bl) is closed off by means of a penetrable membrane (4c) , in that the bottom (2) is executed with a device (2b) projecting towards the agitator disc so arranged, when mixing is complete, as to penetrate the membrane (4c) when the agitator (4) is displaced axially against the bottom (2) .
4. Arrangement in accordance with Patent Claim 1, characterized in that the lid (3) exhibits an evacuation channel (3a) capable of connection to a vacuum source and so executed tha , when the lid (3) is fitted, it discharges into the internal space of the mixing cylinder (1).
5. Arrangement in accordance with Patent Claim 1, characterized in that the mixing cylinder (1) is transparent.
6. Arrangement in accordance with Patent Claim 2, characterized in that the agitator rod (4b) exhibits at its outer end a funnel intended to facilitate the filling of the components via the channel (4bl).
PCT/SE1990/000018 1989-05-03 1990-01-11 Device for preparing bone cement WO1990013264A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP90903630A EP0470959B1 (en) 1989-05-03 1990-01-11 Device for preparing bone cement
DE69022047T DE69022047T2 (en) 1989-05-03 1990-01-11 ARRANGEMENT FOR PRODUCING BONE CEMENT.
NO19914245A NO314923B1 (en) 1989-05-03 1991-10-30 Method and apparatus for making bone cement
KR1019910701507A KR0131143B1 (en) 1989-05-03 1991-11-01 Device for preparing bone cement device for preparing bone lement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8901599-4 1989-05-03
SE8901599A SE462315B (en) 1989-05-03 1989-05-03 DEVICE FOR MANUFACTURING BENCEMENT

Publications (1)

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WO1990013264A1 true WO1990013264A1 (en) 1990-11-15

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US (1) US5252301A (en)
EP (1) EP0470959B1 (en)
JP (1) JP2915567B2 (en)
KR (1) KR0131143B1 (en)
AT (1) ATE126993T1 (en)
AU (1) AU633058B2 (en)
CA (1) CA2054196C (en)
DE (1) DE69022047T2 (en)
DK (1) DK0470959T3 (en)
ES (1) ES2078336T3 (en)
NO (1) NO314923B1 (en)
SE (1) SE462315B (en)
WO (1) WO1990013264A1 (en)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005415A1 (en) * 1992-08-28 1994-03-17 Klaus Draenert Process and device for vacuum mixing of substances
EP0603871A2 (en) * 1992-12-23 1994-06-29 Volkmar Dr. Jansson Process and apparatus for mixing and applying bone cement
EP0768067A3 (en) * 1995-10-10 1998-02-11 Kwan-Ho Chan Bone cement preparation kit having a breakable mixing shaft forming an output port
EP0986995A1 (en) * 1998-09-16 2000-03-22 Sulzer Orthopädie AG Transfer device for bone cement
EP1005901A2 (en) * 1995-11-13 2000-06-07 Cemvac System Aktiebolag Method and device for mixing components for bone cement in a mixing vessel
EP1090609A1 (en) * 1999-10-07 2001-04-11 NGK Spark Plug Company Limited Device and method for preparing calcium phosphate-based cement
WO2001070146A2 (en) * 2000-02-28 2001-09-27 Coripharm Medizinprodukte Gmbh & Co. Kg Preparation and application device for implant materials
WO2001085070A1 (en) * 2000-05-05 2001-11-15 Coripharm Medizinprodukte Gmbh & Co. Kg Preparation and application device for materials to be prepared as a paste-like flowable mass, especially bone cement
US6367962B1 (en) 1998-12-21 2002-04-09 Ngk Spark Plug Co., Ltd. Device and method for preparing calcium phosphate-based bone cement
US7393342B2 (en) 2003-05-12 2008-07-01 Stryker Corporation Bone cement mixing and delivery system including a delivery gun and a cartridge having a piston, the delivery gun configured to release the piston
WO2009059040A1 (en) 2007-10-31 2009-05-07 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
CN104276350A (en) * 2013-07-08 2015-01-14 贺利氏医疗有限公司 Device for storing and mixing bone cement
US20150230846A1 (en) * 2014-02-19 2015-08-20 Spinal Generations, Llc Compressible mixing and delivery system for medical substances
US9186635B2 (en) 2009-03-17 2015-11-17 Stryker Ireland Limited Vacuum mixing device for bone cement and method for mixing bone cement in said device
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Publication number Priority date Publication date Assignee Title
SE510490C2 (en) * 1992-02-07 1999-05-31 Scandimed International Ab Process for producing bone cement and apparatus for carrying out the process
SE470303B (en) * 1992-04-29 1994-01-17 Cemvac System Ab Apparatus for the preparation of bone cement
SE500430C2 (en) * 1993-05-10 1994-06-27 Cemvac System Ab Device for loading bone cement components into a pressurized mixing vessel
EP0705135B1 (en) * 1993-06-21 1997-08-27 Cemvac System Aktiebolag Apparatus for the preparation of bone cement
US5368386A (en) * 1993-11-16 1994-11-29 Murray; William M. Manual bone cement mixing device
GB9403362D0 (en) * 1994-02-22 1994-04-13 Summit Medical Ltd Bone cement mixing apparatus
DE4409610C3 (en) * 1994-03-21 2001-09-20 Scandimed Internat Ab Sjoebo Mixing device
US5462356A (en) * 1994-06-01 1995-10-31 Murray; William M. Bone and dental cement method and preform
DE4425218A1 (en) * 1994-07-16 1996-01-18 Merck Patent Gmbh Device for mixing and discharging bone cement
SE504683C2 (en) * 1995-05-03 1997-04-07 Astra Ab Device for mixing a pharmaceutical composition with another agent
US5549381A (en) * 1995-05-19 1996-08-27 Hays; Greta J. Method and apparatus for mixing polymeric bone cement components
US5779356A (en) * 1996-02-21 1998-07-14 Chan; Kwan-Ho Apparatus and method for mixing first and second components of a bone cement in a vacuum
US5797680A (en) * 1996-09-05 1998-08-25 Murray; William M. Manual bone cement mixing system with vacuum pump start-stop device
US6349828B1 (en) 1997-02-06 2002-02-26 Ferris Pharmaceuticals Inc. Tamper evident packaging
US6007237A (en) * 1997-05-29 1999-12-28 Latto; Brian Vortex ring mixer controlled mixing device
US5934803A (en) * 1997-10-30 1999-08-10 Physical Systems, Inc. Apparatus and method for mixing multi-part reaction materials under vacuum
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
US6120174A (en) * 1999-01-14 2000-09-19 Bristol-Myers Squibb Apparatus and method for mixing and dispensing bone cement
US6116773A (en) * 1999-01-22 2000-09-12 Murray; William M. Bone cement mixer and method
US6296149B1 (en) 1999-04-16 2001-10-02 Depuy Orthopaedics, Inc. Monomer delivery device for bone cement delivery system
US6254268B1 (en) 1999-07-16 2001-07-03 Depuy Orthopaedics, Inc. Bone cement mixing apparatus
US6655828B2 (en) * 2000-12-01 2003-12-02 Depuy Orthopaedics, Inc. Bone cement mixing apparatus having improved mixing blade configuration
US7008433B2 (en) 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
DK1395208T3 (en) 2001-06-14 2007-05-07 Cemvac System Ab Method of producing bone cement and device for practicing the method
SE522098C2 (en) 2001-12-20 2004-01-13 Bone Support Ab Artificial bone mineral substitute material useful as an X-ray contrast medium comprises ceramic and water soluble non-ionic X-ray contrast agent
EP2130579B1 (en) * 2002-03-14 2011-10-05 Stryker Corporation Mixer for mixing bone cement
US6921192B2 (en) 2002-03-29 2005-07-26 Depuy Orthopaedics, Inc. Bone cement mixing apparatus
GB2398741B (en) * 2003-02-05 2005-04-13 Summit Medical Ltd Orthopaedic cement mixing device
EP1614403B2 (en) 2003-03-14 2014-06-18 Depuy Spine, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US7794408B2 (en) * 2003-03-28 2010-09-14 Ethicon, Inc. Tissue collection device and methods
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US20050128867A1 (en) * 2003-05-12 2005-06-16 Henniges Bruce D. Bone cement mixing and delivery system
WO2006011152A2 (en) 2004-06-17 2006-02-02 Disc-O-Tech Medical Technologies, Ltd. Methods for treating bone and other tissue
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
US8062270B2 (en) 2003-07-15 2011-11-22 Spinal Generations, Llc Method and device for delivering medicine to bone
US8034003B2 (en) 2003-09-11 2011-10-11 Depuy Mitek, Inc. Tissue extraction and collection device
US7611473B2 (en) 2003-09-11 2009-11-03 Ethicon, Inc. Tissue extraction and maceration device
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
US7524103B2 (en) 2003-11-18 2009-04-28 Boston Scientific Scimed, Inc. Apparatus for mixing and dispensing a multi-component bone cement
EP1708654B1 (en) * 2003-12-01 2007-05-09 Broockeville Corporation N.V. A two-component mixing and dispensing device
SE527528C2 (en) * 2004-06-22 2006-04-04 Bone Support Ab Apparatus for the preparation of curable pulp and use of the apparatus
US8038682B2 (en) 2004-08-17 2011-10-18 Boston Scientific Scimed, Inc. Apparatus and methods for delivering compounds into vertebrae for vertebroplasty
US20060052760A1 (en) * 2004-08-20 2006-03-09 Ulrich Batzdorf Bone dust accumulator
US8029183B2 (en) * 2005-02-23 2011-10-04 Biomet Manufacturing Corp. Apparatus for mixing bone cement
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
CN101516412B (en) 2006-09-14 2014-02-12 德普伊斯派尔公司 Bone cement and use method thereof
AU2007311451A1 (en) 2006-10-19 2008-04-24 Depuy Spine, Inc. Fluid delivery system
SE531600C2 (en) * 2007-10-10 2009-06-02 Ortoviva Ab Mixing system and mixing procedure for medical purposes
DE102007061696B4 (en) * 2007-12-19 2010-03-18 Heraeus Medical Gmbh Mixing device, especially for bone cements
WO2011082015A2 (en) * 2009-12-31 2011-07-07 Cook Incorporated Vertebroplasty cement mixer injector device
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
CH702757A1 (en) * 2010-02-22 2011-08-31 Medmix Systems Ag Syringe-like mixing device with distally option for self mixing element.
PL2958603T3 (en) 2013-02-20 2018-10-31 Bone Support Ab Improved setting of hardenable bone substitute
DE102015116797B4 (en) 2015-10-02 2018-08-23 Heraeus Medical Gmbh Apparatus and method for storing and mixing a bone cement
CN111729583A (en) * 2020-06-30 2020-10-02 海盐华港印刷股份有限公司 Efficient automatic ink device of transferring of printing

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK123745B (en) * 1967-03-07 1972-07-31 Prod Res & Chem Corp Syringe for mixing at least two components.
FR2286657A1 (en) * 1974-10-01 1976-04-30 Toulouse Inst Serotherapie Double effect syringe for animal vaccination - with disc valve in piston and inlet for successive doses
SE447785B (en) * 1985-12-23 1986-12-15 Mit Ab DEVICE FOR APPLIANCES TO ALLOW BENCEMENT MIXING UNDER VACUUM
WO1987005492A1 (en) * 1986-03-21 1987-09-24 Klaus Draenert Device and process for mixing and filling with bone cement
WO1988003811A1 (en) * 1986-11-19 1988-06-02 Laboratorium Für Experimentelle Chirurgie, Forschu Method and apparatus for preparing a self-curing two-component powder liquid bone cement

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2580316A (en) * 1949-04-12 1951-12-25 Golden State Company Ltd Apparatus for rapid solution and/or suspension of powdered solids
CA1113894A (en) * 1978-01-07 1981-12-08 Hans W. Korte-Jungermann Injection cartridge
DE8335529U1 (en) * 1983-12-10 1984-03-08 Upat Gmbh & Co, 7830 Emmendingen SPRAY CARTRIDGE
JPS61111130A (en) * 1984-11-02 1986-05-29 Oki Electric Ind Co Ltd Method and apparatus for mixing liquid
DE3708803A1 (en) * 1987-03-18 1988-09-29 Fischbach A Kunststoff Kg MIXING DEVICE FOR PASTOESE MULTI-COMPONENT DIMENSIONS
US4973168A (en) * 1989-01-13 1990-11-27 Chan Kwan Ho Vacuum mixing/bone cement cartridge and kit

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK123745B (en) * 1967-03-07 1972-07-31 Prod Res & Chem Corp Syringe for mixing at least two components.
FR2286657A1 (en) * 1974-10-01 1976-04-30 Toulouse Inst Serotherapie Double effect syringe for animal vaccination - with disc valve in piston and inlet for successive doses
SE447785B (en) * 1985-12-23 1986-12-15 Mit Ab DEVICE FOR APPLIANCES TO ALLOW BENCEMENT MIXING UNDER VACUUM
WO1987005492A1 (en) * 1986-03-21 1987-09-24 Klaus Draenert Device and process for mixing and filling with bone cement
WO1988003811A1 (en) * 1986-11-19 1988-06-02 Laboratorium Für Experimentelle Chirurgie, Forschu Method and apparatus for preparing a self-curing two-component powder liquid bone cement

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5857771A (en) * 1992-08-28 1999-01-12 Draenert; Klaus Apparatus for removing gas inclusions from mixing of liquid and powder components and for vaccum mixing such components
WO1994005415A1 (en) * 1992-08-28 1994-03-17 Klaus Draenert Process and device for vacuum mixing of substances
EP0603871A2 (en) * 1992-12-23 1994-06-29 Volkmar Dr. Jansson Process and apparatus for mixing and applying bone cement
EP0603871A3 (en) * 1992-12-23 1994-09-07 Jansson Volkmar Process and apparatus for mixing and applying bone cement.
EP0768067A3 (en) * 1995-10-10 1998-02-11 Kwan-Ho Chan Bone cement preparation kit having a breakable mixing shaft forming an output port
EP1005901A2 (en) * 1995-11-13 2000-06-07 Cemvac System Aktiebolag Method and device for mixing components for bone cement in a mixing vessel
EP1005901A3 (en) * 1995-11-13 2002-10-09 Cemvac System Aktiebolag Method and device for mixing components for bone cement in a mixing vessel
EP0986995A1 (en) * 1998-09-16 2000-03-22 Sulzer Orthopädie AG Transfer device for bone cement
US6238399B1 (en) 1998-09-16 2001-05-29 Sulzer Orthopaedie Ag Filling transfer apparatus for bone cement
US6361539B1 (en) 1998-09-16 2002-03-26 Sulzer Orthopaedie Ag Filling transfer apparatus for bone cement
US6367962B1 (en) 1998-12-21 2002-04-09 Ngk Spark Plug Co., Ltd. Device and method for preparing calcium phosphate-based bone cement
EP1090609A1 (en) * 1999-10-07 2001-04-11 NGK Spark Plug Company Limited Device and method for preparing calcium phosphate-based cement
US6550957B2 (en) 1999-10-07 2003-04-22 Ngk Spark Plug Co., Ltd. Device and method for preparing calcium phosphate-based cement
US6796701B2 (en) * 2000-02-28 2004-09-28 Coripharm Medizinprodukte Gmbh & Co. Kg Preparation and application device for implant materials with hand-operated pump
WO2001070146A2 (en) * 2000-02-28 2001-09-27 Coripharm Medizinprodukte Gmbh & Co. Kg Preparation and application device for implant materials
WO2001070146A3 (en) * 2000-02-28 2002-03-14 Coripharm Medizinprodukte Gmbh Preparation and application device for implant materials
WO2001085070A1 (en) * 2000-05-05 2001-11-15 Coripharm Medizinprodukte Gmbh & Co. Kg Preparation and application device for materials to be prepared as a paste-like flowable mass, especially bone cement
US8061887B2 (en) 2003-05-12 2011-11-22 Stryker Corporation Cartridge in which bone cement is mixed and from which bone cement is delivered, the cartridge having a compressible blade with plural vanes
US7393342B2 (en) 2003-05-12 2008-07-01 Stryker Corporation Bone cement mixing and delivery system including a delivery gun and a cartridge having a piston, the delivery gun configured to release the piston
US7677418B2 (en) 2003-05-12 2010-03-16 Stryker Corporation Bone cement cartridge with a releasably locked drive piston, the piston configured to be unlocked by a delivery device
US8353622B2 (en) 2003-05-12 2013-01-15 Stryker Corporation Cartridge from which bone cement is discharged, the cartridge having a removably coupled nozzle
EP2203200A1 (en) * 2007-10-31 2010-07-07 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
EP2203200A4 (en) * 2007-10-31 2014-04-09 Ultradent Products Inc Mixing device including a plunging mixing member for use with a syringe
WO2009059040A1 (en) 2007-10-31 2009-05-07 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
US9186635B2 (en) 2009-03-17 2015-11-17 Stryker Ireland Limited Vacuum mixing device for bone cement and method for mixing bone cement in said device
US9999459B2 (en) 2009-03-17 2018-06-19 Stryker European Holdings I, Llc Vacuum mixing device for bone cement and method for mixing bone cement in said device
US9642774B2 (en) 2011-09-07 2017-05-09 Stryker European Holdings I, Llc Liquid container with predetermined breaking point
CN104276350A (en) * 2013-07-08 2015-01-14 贺利氏医疗有限公司 Device for storing and mixing bone cement
US9840029B2 (en) 2013-07-08 2017-12-12 Heraeus Medical Gmbh Device for storing and mixing bone cement
EP2823881A1 (en) * 2013-07-08 2015-01-14 Heraeus Medical GmbH Device and method for storing and mixing bone cement
US20150230846A1 (en) * 2014-02-19 2015-08-20 Spinal Generations, Llc Compressible mixing and delivery system for medical substances
US10653470B2 (en) * 2014-02-19 2020-05-19 Spinal Generation, LLC Compressible mixing and delivery system for medical substances
EP3695797A1 (en) 2019-02-18 2020-08-19 Heraeus Medical GmbH Bone cement applicator with clampable discharge plunger
US11701156B2 (en) 2019-02-18 2023-07-18 Heraeus Medical Gmbh Bone cement applicator with clampable delivery plunger

Also Published As

Publication number Publication date
US5252301A (en) 1993-10-12
AU5155190A (en) 1990-11-29
ES2078336T3 (en) 1995-12-16
KR920700587A (en) 1992-08-10
CA2054196A1 (en) 1990-11-04
NO314923B1 (en) 2003-06-16
EP0470959B1 (en) 1995-08-30
AU633058B2 (en) 1993-01-21
DE69022047D1 (en) 1995-10-05
SE462315B (en) 1990-06-11
DK0470959T3 (en) 1995-12-18
NO914245L (en) 1991-10-30
JPH04507200A (en) 1992-12-17
NO914245D0 (en) 1991-10-30
JP2915567B2 (en) 1999-07-05
ATE126993T1 (en) 1995-09-15
DE69022047T2 (en) 1996-04-11
SE8901599D0 (en) 1989-05-03
KR0131143B1 (en) 1998-04-14
EP0470959A1 (en) 1992-02-19
CA2054196C (en) 1999-01-19

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