WO1993020865A1 - Pressure monitor - Google Patents

Pressure monitor Download PDF

Info

Publication number
WO1993020865A1
WO1993020865A1 PCT/DK1993/000122 DK9300122W WO9320865A1 WO 1993020865 A1 WO1993020865 A1 WO 1993020865A1 DK 9300122 W DK9300122 W DK 9300122W WO 9320865 A1 WO9320865 A1 WO 9320865A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
pressure monitor
branch tube
pressure
light
Prior art date
Application number
PCT/DK1993/000122
Other languages
French (fr)
Inventor
Allan Hemmingsen
Bo Steffensen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Priority to US08/313,183 priority Critical patent/US5741216A/en
Priority to EP93911750A priority patent/EP0634940B1/en
Priority to DE69312480T priority patent/DE69312480T2/en
Priority to JP5517913A priority patent/JPH07505550A/en
Publication of WO1993020865A1 publication Critical patent/WO1993020865A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure

Definitions

  • the inventions relates to pressure monitors and to be more specific to pressure monitors for measuring the pressure in a catheter. From WO 90/07942 it is known that the overall correct function of an infusion pump may be supervised by considering the course of the pressure in the outlet catheter during each pumping cycle. It is important that the actual pressure in the very catheter is measured and not just the resistance a piston exerts against movement.
  • a monitor comprising a light emitting device and a light measuring device placed opposite each other leaving a space for insertion of a measuring zone of the catheter between these parts, this measuring zone lying downstream of a possible output valve of a pump, and a computer circuit transforming the signals from the light measuring part into signals representative to the pressure.
  • the light source may be one or more cooperating surface light emitting diodes jointly having a size corresponding to the size of the measuring zone.
  • the photo sensitive device may be formed by one or more photo cells working in parallel and jointly having a size corresponding to the size of the light emitting device.
  • the measuring zone may be a part of the catheter tubing or may be an appendix to the catheter, this appendix forming a manometer tube.
  • the light measuring device may appropriately be a linear array of mutually independent photocells, this array having a length corresponding to the length of the branch tube. With this embodiment of the light measuring part it can be measured to which extent the infusion liquid rises in the manometer tube.
  • Catheters for infusion pumps may have the shape of a tubing forming the complete flow path for the liquid to be infused from a reservoir.
  • the pumping function may be obtained by part of the catheter forming a part of a peristaltic pump or being provided with another sort of pumping unit.
  • the manometer tube may be provided in this pumping unit downstream of the outlet valve of this unit. Thereby it is possible to mould the pumping unit with the manometer tube to obtain a more precise manometer tube.
  • the invention also comprises a catheter provided with a branch tube forming a manometer tube.
  • This branch tube may appropriately be provided near a pump delivering an infusion liquid through the catheter, but downstream in relation to the output valve function of this pump.
  • a catheter may comprise a pumping unit forming a part of this catheter, and the branch tune may be provided as a bore in this unit.
  • Figure 1 schematically shows a monitor comprising a light emitting part and a light measuring part with an interjacent measuring zone of a catheter
  • Figure 2 schematically shows a monitor as shown in
  • Figure 3 schematically shows a monitor measuring the level in a manometer tube.
  • a pressure monitor for measuring the actual pressure in a catheter is shown schematically in Figure 1.
  • the monitor comprises a light source 1 which may be a light emitting diode, LED, emitting its light from an elongated surface, a photo cell 2 for receiving light on a surface of about the same size and shape as the light diode.
  • the LED and the photo cell are placed opposite each other and spaced so far that room is made for accommodating a measuring zone of a catheter 3.
  • FIG. 2 Another embodiment of a pressure monitor is shown in Figure 2.
  • the catheter 3 not the catheter 3 itself but an appendix 4 on this catheter is inserted between the light source 1 and the photo cell 2.
  • the appendix has the shape of a short tube, the bore of which communicates with the clear of the catheter and is closed at the outer end of the appendix.
  • a manometer tube is provided.
  • the catheter is filled with liquid, some air will be trapped in the manometer tube, and a surface 5 separating air and liquid will appear in the manometer tube.
  • the liquid in the catheter is set under pressure, this surface will be forced further up into the manometer tube.
  • the manometer tube is placed between the light source 1 and the photo cell 2, the light transmission will be influenced by the varying position of the liquid surface 5, as the transmission properties of the liquid filled part of the manometer tube will be different from the transmission properties of the part filled with air.
  • FIG 3 shows an embodiment of a monitor measuring the light transmission perpendicular to a manometer tube.
  • This monitor has a light source 1 as the embodiments according to Figures 1 and 2, but instead of one photo cell or more photocells operating in parallel it has an array of photo cells 5, each supplying its own output signal. Thereby it is made possible to read exactly the position of the liquid surface 5, as a distinct difference in transmission may be seen between the cells in the array receiving light from the light source through the air filled part and the cells receiving the light through the liquid filled part of the manometer tube.
  • the position of the separating surface is noticed and further the end of the appendix may be noticed, as a distinct difference in transmission is also seen between the part of the appendix having an air filled bore and the solid part closing the outer end of the branch tube.
  • the position of the separating surface may be read with a precision depending on the number, size, and spacing of the photo cells 6 in the array.
  • the absolute pressure may be calculated by recognizing the law for confined gasses.
  • an output from each cell must lead to the computer.
  • a circuit may be provided in connection with the array to transform the output signal to a sequential signal.
  • the monitor is intended to be a part of an infusion pump frequently infusing doses of liquid. During each infusion the course of the pressure in the catheter has to be monitored to supervise that the doses are actually infused and no functional errors occur. Consequently, the monitor needs only be activated in connection with the frequent infusion cycles, and power may be saved by turning off the light source between these cycles.

Abstract

A pressure monitor for directly measuring the pressure in a liquid in a catheter, comprising light emitting means (1), photo sensitive means (2), receiving the light from the light emitting means (1) and transforming the light received into electric signals, and between the light emitting and light receiving means (1 and 2) a space accommodating a measuring zone of the catheter in which the pressure is measured. The measuring zone may be a part of the catheter tubing (3) or a branch pipe (4) of said tubing (3), the free end of this branch pipe (4) being closed. The light transmitted through the measuring zone varies in accordance with the pressure in the catheter.

Description

Pressure Monitor
The inventions relates to pressure monitors and to be more specific to pressure monitors for measuring the pressure in a catheter. From WO 90/07942 it is known that the overall correct function of an infusion pump may be supervised by considering the course of the pressure in the outlet catheter during each pumping cycle. It is important that the actual pressure in the very catheter is measured and not just the resistance a piston exerts against movement.
It is the object of the invention to provide a pressure monitor measuring the pressure in the catheter directly.
This is obtained by a monitor comprising a light emitting device and a light measuring device placed opposite each other leaving a space for insertion of a measuring zone of the catheter between these parts, this measuring zone lying downstream of a possible output valve of a pump, and a computer circuit transforming the signals from the light measuring part into signals representative to the pressure.
The light source may be one or more cooperating surface light emitting diodes jointly having a size corresponding to the size of the measuring zone.
Correspondingly, the photo sensitive device may be formed by one or more photo cells working in parallel and jointly having a size corresponding to the size of the light emitting device.
The measuring zone may be a part of the catheter tubing or may be an appendix to the catheter, this appendix forming a manometer tube.
When the manometer tube solution is used, the light measuring device may appropriately be a linear array of mutually independent photocells, this array having a length corresponding to the length of the branch tube. With this embodiment of the light measuring part it can be measured to which extent the infusion liquid rises in the manometer tube. Catheters for infusion pumps may have the shape of a tubing forming the complete flow path for the liquid to be infused from a reservoir. The pumping function may be obtained by part of the catheter forming a part of a peristaltic pump or being provided with another sort of pumping unit. In the last mentioned case, the manometer tube may be provided in this pumping unit downstream of the outlet valve of this unit. Thereby it is possible to mould the pumping unit with the manometer tube to obtain a more precise manometer tube.
The invention also comprises a catheter provided with a branch tube forming a manometer tube. This branch tube may appropriately be provided near a pump delivering an infusion liquid through the catheter, but downstream in relation to the output valve function of this pump.
A catheter may comprise a pumping unit forming a part of this catheter, and the branch tune may be provided as a bore in this unit.
In the following the invention will be described with reference to the drawingr wherein
Figure 1 schematically shows a monitor comprising a light emitting part and a light measuring part with an interjacent measuring zone of a catheter,
Figure 2 schematically shows a monitor as shown in
Figure 1 where the measuring zone of the catheter is provided as an appendix to the catheter,
Figure 3 , schematically shows a monitor measuring the level in a manometer tube.
A pressure monitor for measuring the actual pressure in a catheter is shown schematically in Figure 1. The monitor comprises a light source 1 which may be a light emitting diode, LED, emitting its light from an elongated surface, a photo cell 2 for receiving light on a surface of about the same size and shape as the light diode. The LED and the photo cell are placed opposite each other and spaced so far that room is made for accommodating a measuring zone of a catheter 3.
It has appeared that the light transmission through the liquid filled catheter varies with the internal pressure in the catheter, and consequently an output signal reflecting the pressure variations in the catheter may be obtained from the photo cell. The signal is lead to a calculating unit setting the zero point, when a new catheter is inserted. Advantage is taken of the fact that a measurement of the absolute pressure is not needed, as the monitoring method stated in WO 90/07942 only considers variations in the pressure from one pumping cycle to the other.
Another embodiment of a pressure monitor is shown in Figure 2. In this embodiment, not the catheter 3 itself but an appendix 4 on this catheter is inserted between the light source 1 and the photo cell 2. The appendix has the shape of a short tube, the bore of which communicates with the clear of the catheter and is closed at the outer end of the appendix. Thereby a manometer tube is provided. When the catheter is filled with liquid, some air will be trapped in the manometer tube, and a surface 5 separating air and liquid will appear in the manometer tube. When the liquid in the catheter is set under pressure, this surface will be forced further up into the manometer tube. When the manometer tube is placed between the light source 1 and the photo cell 2, the light transmission will be influenced by the varying position of the liquid surface 5, as the transmission properties of the liquid filled part of the manometer tube will be different from the transmission properties of the part filled with air.
Figure 3 shows an embodiment of a monitor measuring the light transmission perpendicular to a manometer tube. This monitor has a light source 1 as the embodiments according to Figures 1 and 2, but instead of one photo cell or more photocells operating in parallel it has an array of photo cells 5, each supplying its own output signal. Thereby it is made possible to read exactly the position of the liquid surface 5, as a distinct difference in transmission may be seen between the cells in the array receiving light from the light source through the air filled part and the cells receiving the light through the liquid filled part of the manometer tube.
When the catheter is filled with unpressurized liquid, the position of the separating surface is noticed and further the end of the appendix may be noticed, as a distinct difference in transmission is also seen between the part of the appendix having an air filled bore and the solid part closing the outer end of the branch tube. Hereafter the position of the separating surface may be read with a precision depending on the number, size, and spacing of the photo cells 6 in the array. Hereby the absolute pressure may be calculated by recognizing the law for confined gasses.
To discriminate between the signals from the photo cells 6 ±τi the array, an output from each cell must lead to the computer. Alternatively, a circuit may be provided in connection with the array to transform the output signal to a sequential signal.
The monitor is intended to be a part of an infusion pump frequently infusing doses of liquid. During each infusion the course of the pressure in the catheter has to be monitored to supervise that the doses are actually infused and no functional errors occur. Consequently, the monitor needs only be activated in connection with the frequent infusion cycles, and power may be saved by turning off the light source between these cycles.

Claims

1. A pressure monitor for directly monitoring the pressure of a liquid in a catheter, characterized in, that it comprises a light emitting device and a photo sensitive device receiving light from the light emitting device and transforming this light into electric signals, and an intermediate space accommodating a measuring zone of the catheter in which the pressure should be measured.
2. A pressure monitor according to claim 1, characterized in, that the light source comprises one or more cooperating surface light emitting diodes jointly having a size corresponding to the size of the measuring zone.
3. A pressure monitor according to claim 1 or 2, characterized in, that the measuring zone is a part of the tubing constituting the catheter.
4. A pressure monitor according to claim 1 or 2 , characterized in, that the measuring zone is branch tube to the catheter, the outer end of this branch tube being closed.
5. A pressure monitor according to claim 4, characterized in, that the branch tube is provided in a pump part provided as an integral part of the catheter, the branch tube being provided downstream in relation to valve means in the pump part.
6. A pressure monitor according to any of the preceding claims, characterized in, that the photo sensitive device comprises one or more cooperating photocells working in parallel and jointly corresponding to the size of the joint light emitting surface of the light source.
7. A pressure monitor according to claim 4 or 5, characterized in, that the photo sensitive device is a linear array of mutually independent photo cells, this array having a length corresponding to the length of the branch tube.
8. A catheter for use with a pressure monitor according to any of the claims 4 - 7, characterized in, that the catheter is provided with a branch tube forming a manometer tube.
9. A catheter according to claim 8, characterized in, that the branch tube is provided near a pump delivering an infusion liquid through the catheter, but downstream in relation to an output valve function of this pump.
10. A catheter according to claim 8 or 9, characterized in, that the branch tube is formed as a bore in a pumping unit forming a part of the catheter.
PCT/DK1993/000122 1992-04-10 1993-04-01 Pressure monitor WO1993020865A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US08/313,183 US5741216A (en) 1992-04-10 1993-04-01 Pressure monitor
EP93911750A EP0634940B1 (en) 1992-04-10 1993-04-01 Pressure monitor
DE69312480T DE69312480T2 (en) 1992-04-10 1993-04-01 PRESSURE MONITOR
JP5517913A JPH07505550A (en) 1992-04-10 1993-04-01 pressure monitor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK0480/92 1992-04-10
DK92480A DK48092D0 (en) 1992-04-10 1992-04-10 APPARATUS

Publications (1)

Publication Number Publication Date
WO1993020865A1 true WO1993020865A1 (en) 1993-10-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK1993/000122 WO1993020865A1 (en) 1992-04-10 1993-04-01 Pressure monitor

Country Status (8)

Country Link
US (1) US5741216A (en)
EP (1) EP0634940B1 (en)
JP (1) JPH07505550A (en)
AT (1) ATE155693T1 (en)
AU (1) AU4259993A (en)
DE (1) DE69312480T2 (en)
DK (1) DK48092D0 (en)
WO (1) WO1993020865A1 (en)

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EP2022519A1 (en) * 2007-08-10 2009-02-11 F. Hoffmann-La Roche AG Device for detecting a pressure change in the liquid path of a micro dosing apparatus
EP2186535A1 (en) 2008-11-14 2010-05-19 F.Hoffmann-La Roche Ag Micro-fluidic "dead-end channel"-structure for pressure measurement within a fluid channel on the basis of the change of the volume of a trapped gas bubble

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US6523414B1 (en) 2001-04-16 2003-02-25 Zevex, Inc. Optical pressure monitoring system
US6659976B2 (en) 2001-04-16 2003-12-09 Zevek, Inc. Feeding set adaptor
US20050160858A1 (en) * 2002-07-24 2005-07-28 M 2 Medical A/S Shape memory alloy actuator
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EP2022519A1 (en) * 2007-08-10 2009-02-11 F. Hoffmann-La Roche AG Device for detecting a pressure change in the liquid path of a micro dosing apparatus
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Also Published As

Publication number Publication date
US5741216A (en) 1998-04-21
DK48092D0 (en) 1992-04-10
DE69312480T2 (en) 1998-02-19
EP0634940A1 (en) 1995-01-25
EP0634940B1 (en) 1997-07-23
DE69312480D1 (en) 1997-09-04
JPH07505550A (en) 1995-06-22
AU4259993A (en) 1993-11-18
ATE155693T1 (en) 1997-08-15

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