WO1995027906A3 - Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging - Google Patents

Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging Download PDF

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Publication number
WO1995027906A3
WO1995027906A3 PCT/US1995/004034 US9504034W WO9527906A3 WO 1995027906 A3 WO1995027906 A3 WO 1995027906A3 US 9504034 W US9504034 W US 9504034W WO 9527906 A3 WO9527906 A3 WO 9527906A3
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WO
WIPO (PCT)
Prior art keywords
sequence
ste
spatial
interest
volume
Prior art date
Application number
PCT/US1995/004034
Other languages
French (fr)
Other versions
WO1995027906A2 (en
Inventor
Stefan Posse
Denis Lebihan
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Us Health
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Publication date
Application filed by Us Health filed Critical Us Health
Priority to AU22357/95A priority Critical patent/AU2235795A/en
Publication of WO1995027906A2 publication Critical patent/WO1995027906A2/en
Publication of WO1995027906A3 publication Critical patent/WO1995027906A3/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/4833—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/4838—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective suppression or saturation of MR signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G01R33/5616—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using gradient refocusing, e.g. EPI

Abstract

A method and system for providing prelocalization of a volume of interest and for rapidly acquiring a data set for generating spectroscopic images. Spatial prelocalization of a volume of interest is achieved by providing a presuppression sequence before a stimulated echo (STE) sequence and a suppression sequence during the mixing time (TM) interval of the STE sequence. The presuppression sequence includes a spatial suppression sequence to selectively saturate slices that intersect the plane selected by the STE sequence in order to define a boundary for the volume of interest, and this spatial suppression sequence is substantially repeated during the TM interval of the STE sequence. Spectroscopic imaging data is acquired by an oversampled echo planar spatial-spectral imaging sequence in which the gradient reversal frequency is an integer factor of n greater than the gradient reversal frequency required to sample the spectral width. Each RF pulse of the STE sequence excites spins in substantially the same plane, and an adaptation of this STE sequence provides for acquiring multiple echoes at different effective echo times without compromising spatial localization of the different echoes.
PCT/US1995/004034 1994-04-08 1995-04-07 Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging WO1995027906A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU22357/95A AU2235795A (en) 1994-04-08 1995-04-07 Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22494294A 1994-04-08 1994-04-08
US08/224,942 1994-04-08
US08/290,348 US5657758A (en) 1994-04-08 1994-08-15 Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging
US08/290,348 1994-08-15

Publications (2)

Publication Number Publication Date
WO1995027906A2 WO1995027906A2 (en) 1995-10-19
WO1995027906A3 true WO1995027906A3 (en) 1996-01-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/004034 WO1995027906A2 (en) 1994-04-08 1995-04-07 Method and system for multidimensional localization and for rapid magnetic resonance spectroscopic imaging

Country Status (3)

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US (1) US5657758A (en)
AU (1) AU2235795A (en)
WO (1) WO1995027906A2 (en)

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US6597936B1 (en) * 2000-11-14 2003-07-22 Koninklijke Philips Electronics, N.V. Focused point oversampling for temporally and spatially resolving dynamic studies
US6556009B2 (en) * 2000-12-11 2003-04-29 The United States Of America As Represented By The Department Of Health And Human Services Accelerated magnetic resonance imaging using a parallel spatial filter
US6611701B2 (en) * 2000-12-30 2003-08-26 Ge Medical Systems Global Technology Company, Llc Method and apparatus for fast breath-held 3D MR data acquisition using variable sampling
CA2490305A1 (en) * 2002-07-11 2004-01-22 Thomas A. Szyperski A method of using g-matrix fourier transformation nuclear magnetic resonance (gft nmr) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
US6806706B2 (en) * 2002-11-26 2004-10-19 Ge Medical Systems Global Technology Company, Llc Modulated chemical shift imaging solvent suppression
US6987997B1 (en) * 2003-06-18 2006-01-17 General Electric Company Method and apparatus for improved metabolite signal separation in MR spectroscopy
JP3992674B2 (en) * 2003-09-25 2007-10-17 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー Magnetic resonance imaging device
US7227356B1 (en) * 2004-09-03 2007-06-05 General Electric Company Method and apparatus of multi-echo MR data acquisition with non-discrete flip angle train
US7920972B2 (en) 2004-10-18 2011-04-05 The Research Foundation Of State University Of New York G-matrix Fourier transformation (GFT) nuclear magnetic resonance (NMR) experiments for resonance assignment and structure determination of organic molecules
US20070055138A1 (en) * 2005-08-22 2007-03-08 Edelman Robert R Accelerated whole body imaging with spatially non-selective radio frequency pulses
US8604787B2 (en) * 2006-04-27 2013-12-10 Stefan Posse Magnetic resonance spectroscopy with real-time correction of motion and frequency drift, and real-time shimming
JP5118052B2 (en) * 2006-10-06 2013-01-16 株式会社日立メディコ Magnetic resonance imaging system
JP5398149B2 (en) * 2007-03-27 2014-01-29 株式会社東芝 Magnetic resonance imaging system
US20120197104A1 (en) * 2009-10-24 2012-08-02 Stc.Unm System and methods for automatic placement of spatial supression regions in mri and mrsi
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
CN102445675B (en) * 2010-10-12 2016-04-27 深圳迈瑞生物医疗电子股份有限公司 Device for restraining electromagnetic interference and adopt the MR imaging apparatus of this device
US9116219B1 (en) * 2011-10-21 2015-08-25 Stc.Unm System and methods for improved real time functional magnetic resonance imaging
US20130300410A1 (en) * 2012-03-30 2013-11-14 Max-Delbrueck- Centrum Fuer Molekulare Medizine Method for fast spin-echo MRT imaging
US9055882B2 (en) * 2012-04-26 2015-06-16 Siemens Aktiengesellschaft Method and apparatus to generate magnetic resonance images
DE102013210652A1 (en) * 2013-06-07 2014-12-11 Siemens Aktiengesellschaft Determining a magnetic resonance system drive sequence and generating an image sequence by means of this magnetic resonance system drive sequence
KR101611451B1 (en) * 2014-11-03 2016-04-11 삼성전자주식회사 Apparatus and method for processing magnetic resonance image

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Also Published As

Publication number Publication date
US5657758A (en) 1997-08-19
WO1995027906A2 (en) 1995-10-19
AU2235795A (en) 1995-10-30

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