WO1996025961A1 - Resorbable extracellular matrix for reconstruction of cartilage tissue - Google Patents
Resorbable extracellular matrix for reconstruction of cartilage tissue Download PDFInfo
- Publication number
- WO1996025961A1 WO1996025961A1 PCT/GB1996/000399 GB9600399W WO9625961A1 WO 1996025961 A1 WO1996025961 A1 WO 1996025961A1 GB 9600399 W GB9600399 W GB 9600399W WO 9625961 A1 WO9625961 A1 WO 9625961A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- matrix
- collagen
- cartilage
- treatment
- cartilage tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3612—Cartilage, synovial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/3654—Cartilage, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Definitions
- the collagen matrix according to the invention can advantageously be used for the production of collagen sheets, which are suitable for use in a wide range of medical indications.
- the invention also provides the use of a matrix according to the invention in guided regeneration of cartilage tissue.
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002213533A CA2213533C (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
US08/894,517 US6326029B1 (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
DE69632313T DE69632313T2 (en) | 1995-02-22 | 1996-02-22 | DESORBABLE EXTRACELLULAR MATRIX FOR RECONSTRUCTION OF A CARTILAGE TISSUE |
AT96903128T ATE265240T1 (en) | 1995-02-22 | 1996-02-22 | DESORBABLE EXTRACELLULAR MATRIX FOR RECONSTRUCTION OF CARTILAGE TISSUE |
EP96903128A EP0810888B1 (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
JP52549796A JP3643381B2 (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for cartilage tissue reconstruction |
US09/473,981 US6352558B1 (en) | 1996-02-22 | 1999-12-29 | Method for promoting regeneration of surface cartilage in a damage joint |
US09/988,805 US7208177B2 (en) | 1995-02-22 | 2001-11-20 | Resorbable extracellular matrix for reconstruction of cartilage |
US11/046,898 US20050186673A1 (en) | 1995-02-22 | 2005-02-01 | Collagen carrier of therapeutic genetic material, and method |
US11/928,387 US20080268053A1 (en) | 1995-02-22 | 2007-10-30 | Collagen carrier of therapeutic genetic material, and method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9503492.2A GB9503492D0 (en) | 1995-02-22 | 1995-02-22 | Chemical product |
GB9503492.2 | 1995-02-22 |
Related Child Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08894517 A-371-Of-International | 1996-02-22 | ||
US08/894,517 A-371-Of-International US6326029B1 (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
US09/473,981 Continuation-In-Part US6352558B1 (en) | 1996-02-22 | 1999-12-29 | Method for promoting regeneration of surface cartilage in a damage joint |
US09/986,757 Continuation-In-Part US6676969B2 (en) | 1995-02-22 | 2001-11-09 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
US09/986,757 Continuation US6676969B2 (en) | 1995-02-22 | 2001-11-09 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996025961A1 true WO1996025961A1 (en) | 1996-08-29 |
Family
ID=10770040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1996/000399 WO1996025961A1 (en) | 1995-02-22 | 1996-02-22 | Resorbable extracellular matrix for reconstruction of cartilage tissue |
Country Status (9)
Country | Link |
---|---|
US (3) | US6326029B1 (en) |
EP (1) | EP0810888B1 (en) |
JP (1) | JP3643381B2 (en) |
AT (1) | ATE265240T1 (en) |
CA (1) | CA2213533C (en) |
DE (1) | DE69632313T2 (en) |
ES (1) | ES2217304T3 (en) |
GB (1) | GB9503492D0 (en) |
WO (1) | WO1996025961A1 (en) |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998040111A1 (en) * | 1997-03-07 | 1998-09-17 | University College London | Tissue implant |
WO1999019005A1 (en) * | 1997-10-10 | 1999-04-22 | Ed Geistlich Söhne Ag Für Chemische Industrie | Membrane for use in guided tissue regeneration |
EP0994694A1 (en) * | 1997-01-15 | 2000-04-26 | Orquest, Inc. | Collagen-polysaccharide matrix for bone and cartilage repair |
WO2001025403A2 (en) * | 1999-10-01 | 2001-04-12 | Consorzio Per Gli Studi Universitari | Bio-artificial substrate for the production of animal and, in particular, human tissues and organs |
US6221109B1 (en) | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
WO2001045764A1 (en) * | 1999-12-20 | 2001-06-28 | Verigen Transplantation Service International Ag | Cellular matrix |
WO2001054735A2 (en) * | 2000-01-28 | 2001-08-02 | Orthogene, Inc. | Gel-infused sponges for tissue repair and augmentation |
FR2812553A1 (en) * | 2000-07-19 | 2002-02-08 | Geistlich Soehne Ag | Bone mineral product and collagen combination for repair of injured joints has porous bone mineral particles derived from natural bone having a crystal structure that of natural bone and being free from all endogenous organic material |
US6352558B1 (en) | 1996-02-22 | 2002-03-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damage joint |
US6379367B1 (en) | 1996-08-30 | 2002-04-30 | Verigen Transplantation Service International (Vtsi) Ag | Method instruments and kit for autologous transplantation |
JP2002527402A (en) * | 1998-10-14 | 2002-08-27 | オークエスト インコーポレイテッド | A method for inducing or enhancing cartilage formation with an extracellular matrix containing GDF-5. |
US6444222B1 (en) | 2001-05-08 | 2002-09-03 | Verigen Transplantation Services International Ag | Reinforced matrices |
EP1254670A1 (en) * | 2001-05-03 | 2002-11-06 | Stichting Katholieke Universiteit | Type II collagen matrices for use in cartilage engineering |
EP1312383A2 (en) * | 2001-11-20 | 2003-05-21 | Ed Geistlich Söhne AG Für Chemische Industrie | Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage |
US6569172B2 (en) | 1996-08-30 | 2003-05-27 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6713085B2 (en) | 2001-04-27 | 2004-03-30 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method and membrane for mucosa regeneration |
EP1416879A2 (en) * | 2001-07-16 | 2004-05-12 | Depuy Products, Inc. | Unitary surgical device and method |
EP1416888A2 (en) * | 2001-07-16 | 2004-05-12 | Depuy Products, Inc. | Meniscus regeneration device and method |
US6866668B2 (en) | 1998-08-14 | 2005-03-15 | Verigen Transplantation Service International (“VTSL”) AG | Methods, instruments and materials for chondrocyte cell transplantation |
WO2005039528A2 (en) | 2003-10-23 | 2005-05-06 | Katharina Beschorner | Composition for the treatment of arthrosis/arthritis, especially for treating joints |
US7141072B2 (en) | 1998-10-05 | 2006-11-28 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering |
US7208177B2 (en) | 1995-02-22 | 2007-04-24 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix for reconstruction of cartilage |
US7429241B2 (en) | 2005-09-29 | 2008-09-30 | Codman & Shurtleff, Inc. | Dural graft and method of preparing the same |
WO2008154888A2 (en) | 2007-06-21 | 2008-12-24 | Hypro Otrokovice S.R.O. | Procedure for the manufacture of a structured multilayer membrane, the structured multilayer membrane and its uses |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US8911763B2 (en) | 1997-10-10 | 2014-12-16 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material and method |
US9034315B2 (en) | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
EP2872071A4 (en) * | 2012-07-11 | 2016-04-20 | Osiris Therapeutics Inc | Methods of manufacturing cartilage products |
EP3043805A4 (en) * | 2013-09-09 | 2017-05-31 | Eran Rosines | Biologic prosthesis and methods of production and use |
CN112154247A (en) * | 2018-05-03 | 2020-12-29 | C.M.I.铰链机械工业有限公司 | Hinge device for refrigerator and furniture |
CN113398338A (en) * | 2021-06-30 | 2021-09-17 | 华东理工大学 | Double-layer repairing film for guiding tissue regeneration and preparation method thereof |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050186673A1 (en) * | 1995-02-22 | 2005-08-25 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material, and method |
ES2208974T3 (en) * | 1996-08-23 | 2004-06-16 | Cook Biotech, Inc. | PROTESIS OF GRAFT, MATERIALS AND METHODS. |
US8716227B2 (en) * | 1996-08-23 | 2014-05-06 | Cook Biotech Incorporated | Graft prosthesis, materials and methods |
US6666892B2 (en) * | 1996-08-23 | 2003-12-23 | Cook Biotech Incorporated | Multi-formed collagenous biomaterial medical device |
US8882850B2 (en) * | 1998-12-01 | 2014-11-11 | Cook Biotech Incorporated | Multi-formed collagenous biomaterial medical device |
US20020095157A1 (en) | 1999-07-23 | 2002-07-18 | Bowman Steven M. | Graft fixation device combination |
US6179840B1 (en) | 1999-07-23 | 2001-01-30 | Ethicon, Inc. | Graft fixation device and method |
US8366787B2 (en) | 2000-08-04 | 2013-02-05 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
US6638312B2 (en) * | 2000-08-04 | 2003-10-28 | Depuy Orthopaedics, Inc. | Reinforced small intestinal submucosa (SIS) |
CA2365376C (en) | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US20040151705A1 (en) * | 2002-03-22 | 2004-08-05 | Shuichi Mizuno | Neo-cartilage constructs and a method for preparation thereof |
US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
EP1416880B1 (en) * | 2001-07-16 | 2011-03-02 | DePuy Products, Inc. | Cartilage repair apparatus |
EP1416874A4 (en) * | 2001-07-16 | 2007-04-18 | Depuy Products Inc | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
WO2003007787A2 (en) | 2001-07-16 | 2003-01-30 | Depuy Products, Inc. | Cartilage repair and regeneration device and method |
AU2002322567B2 (en) | 2001-07-16 | 2007-09-06 | Depuy Products, Inc. | Devices form naturally occurring biologically derived |
US7819918B2 (en) | 2001-07-16 | 2010-10-26 | Depuy Products, Inc. | Implantable tissue repair device |
US7201917B2 (en) * | 2001-07-16 | 2007-04-10 | Depuy Products, Inc. | Porous delivery scaffold and method |
JP2003160506A (en) * | 2001-08-10 | 2003-06-03 | Ed Geistlich Soehne Ag Fuer Chemische Industrie | Collagen carrier of therapeutic genetic material and method |
US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US20040166169A1 (en) * | 2002-07-15 | 2004-08-26 | Prasanna Malaviya | Porous extracellular matrix scaffold and method |
US7824701B2 (en) | 2002-10-18 | 2010-11-02 | Ethicon, Inc. | Biocompatible scaffold for ligament or tendon repair |
US20040078090A1 (en) | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
US20040121943A1 (en) * | 2002-12-20 | 2004-06-24 | Wei-Cherng Hsu | Drug-free biodegradable 3D porous collagen-glycosaminoglycan scaffold |
US7544368B2 (en) | 2002-12-20 | 2009-06-09 | Life Spring Biotech Co., Ltd. | Structure for modulating intraocular pressure |
US8197837B2 (en) | 2003-03-07 | 2012-06-12 | Depuy Mitek, Inc. | Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof |
US8226715B2 (en) * | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
NL1023924C2 (en) * | 2003-07-15 | 2005-01-18 | Stichting Tech Wetenschapp | Tissue replacement material. |
US10583220B2 (en) * | 2003-08-11 | 2020-03-10 | DePuy Synthes Products, Inc. | Method and apparatus for resurfacing an articular surface |
EP2441474B1 (en) | 2003-10-17 | 2015-08-05 | Joslin Diabetes Center, Inc. | Methods and compositions for modulating adipocyte function |
US7316822B2 (en) * | 2003-11-26 | 2008-01-08 | Ethicon, Inc. | Conformable tissue repair implant capable of injection delivery |
US7901461B2 (en) * | 2003-12-05 | 2011-03-08 | Ethicon, Inc. | Viable tissue repair implants and methods of use |
US7666230B2 (en) * | 2003-12-08 | 2010-02-23 | Depuy Products, Inc. | Implant device for cartilage regeneration in load bearing articulation regions |
US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
US8137686B2 (en) | 2004-04-20 | 2012-03-20 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
US8221780B2 (en) * | 2004-04-20 | 2012-07-17 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
US7569233B2 (en) * | 2004-05-04 | 2009-08-04 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050249772A1 (en) * | 2004-05-04 | 2005-11-10 | Prasanna Malaviya | Hybrid biologic-synthetic bioabsorbable scaffolds |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
WO2006050213A2 (en) * | 2004-10-29 | 2006-05-11 | Michalow Alexander E | Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway |
US7513866B2 (en) * | 2004-10-29 | 2009-04-07 | Depuy Products, Inc. | Intestine processing device and associated method |
US7354627B2 (en) * | 2004-12-22 | 2008-04-08 | Depuy Products, Inc. | Method for organizing the assembly of collagen fibers and compositions formed therefrom |
US20100150885A1 (en) * | 2005-06-01 | 2010-06-17 | Joslin Diabetes Center, Inc. | Methods and compositions for inducing brown adipogenesis |
JP4044579B2 (en) * | 2005-08-02 | 2008-02-06 | 株式会社Pgリサーチ | Artificial cartilage tissue |
EP1923457B1 (en) | 2005-08-18 | 2017-06-28 | KOKEN CO., Ltd. | Cell culture support embeddable in vivo |
WO2007026362A2 (en) * | 2005-09-02 | 2007-03-08 | Colbar Lifescience Ltd. | Cross-linked polysaccharide and protein matrices and methods for their preparation |
WO2007035778A2 (en) | 2005-09-19 | 2007-03-29 | Histogenics Corporation | Cell-support matrix and a method for preparation thereof |
US20080026032A1 (en) * | 2006-07-27 | 2008-01-31 | Zubery Yuval | Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use |
CA2661389C (en) * | 2006-09-07 | 2016-04-12 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treating bone cancer |
WO2008078166A2 (en) | 2006-12-22 | 2008-07-03 | Laboratoire Medidom S.A. | In situ system for intra-articular chondral and osseous tissue repair |
ITMI20070458A1 (en) * | 2007-03-07 | 2008-09-08 | Roberto Buda | COMPOSITION CONTAINING MONONUCLEATED CELLS AUTOLOGUE MATRIX IN PIG COLLAGEN UNDER THE FORM OF PASTA AND ITS USE FOR THE PREPARATION OF A MEDICATION FOR SURGICAL TREATMENT |
US9421304B2 (en) | 2007-07-03 | 2016-08-23 | Histogenics Corporation | Method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant |
US8685107B2 (en) | 2007-07-03 | 2014-04-01 | Histogenics Corporation | Double-structured tissue implant and a method for preparation and use thereof |
US20090054984A1 (en) | 2007-08-20 | 2009-02-26 | Histogenics Corporation | Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects |
EP2698173A1 (en) | 2008-02-29 | 2014-02-19 | Coloplast A/S | Compositions and methods for augmentation and regeneration of living tissue in a subject |
WO2009106642A1 (en) * | 2008-02-29 | 2009-09-03 | Coloplast A/S | Biosynthetic cartilaginous matrix and methods for their production |
US20110143429A1 (en) * | 2008-04-30 | 2011-06-16 | Iksoo Chun | Tissue engineered blood vessels |
WO2009134991A2 (en) | 2008-04-30 | 2009-11-05 | Ethicon, Inc. | Tissue engineered blood vessel |
JP2011523357A (en) * | 2008-05-06 | 2011-08-11 | ジョスリン ダイアビーティス センター インコーポレイテッド | Methods and compositions for inducing brown adipocyte differentiation |
US8858698B2 (en) * | 2008-09-05 | 2014-10-14 | Mentor Worldwide Llc | Acellular matrix glue |
US8377432B2 (en) * | 2009-09-02 | 2013-02-19 | Khay-Yong Saw | Method and composition for neochondrogenesis |
WO2014052912A1 (en) | 2012-09-28 | 2014-04-03 | Scripps Health | Methods of differentiating stem cells into chondrocytes |
JP6324395B2 (en) | 2012-10-29 | 2018-05-16 | スクリップス ヘルス | Method of transplanting chondrocytes |
EP2912166B1 (en) | 2012-10-29 | 2019-05-01 | Scripps Health | Methods of producing pluripotent stem cells from chondrocytes |
EP2826495A1 (en) | 2013-07-19 | 2015-01-21 | Geistlich Pharma AG | Biomimetic collagen-hydroxyapatite composite material |
EP3027235A1 (en) | 2013-07-30 | 2016-06-08 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
CN110652381A (en) * | 2019-10-24 | 2020-01-07 | 深圳兰度生物材料有限公司 | Osteochondral repair scaffold and preparation method thereof |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990005755A1 (en) * | 1988-11-21 | 1990-05-31 | Collagen Corporation | Collagen-polymer conjugates |
WO1990013302A1 (en) * | 1989-04-28 | 1990-11-15 | Brigham And Women's Hospital | Novel materials and methods for guided tissue regeneration |
WO1992013565A1 (en) * | 1991-01-31 | 1992-08-20 | Shaw, Robert, Francis | Growth factor containing matrix for the treatment of cartilage lesions |
FR2679778A1 (en) * | 1991-08-02 | 1993-02-05 | Coletica | Use of collagen cross-linked with a cross-linking agent, for the manufacture of a biocompatible suturable membrane affording slow resorption, as well as such a membrane |
WO1993010722A2 (en) * | 1991-11-26 | 1993-06-10 | Research Development Foundation | Fetal membrane tubes for nerve and vessel grafts |
WO1993011723A1 (en) * | 1991-12-17 | 1993-06-24 | Regen Biologics, Inc. | Prosthetic articular cartilage |
WO1993019168A1 (en) * | 1992-03-18 | 1993-09-30 | Mount Sinai Hospital Corporation | Reconstituted cartilage tissue |
WO1995018638A1 (en) * | 1994-01-06 | 1995-07-13 | Ed Geistlich Sohne Ag Fur Chemische Industrie | Membrane |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS173141B1 (en) * | 1973-07-16 | 1977-02-28 | ||
US4129489A (en) * | 1976-02-14 | 1978-12-12 | Ppg Industries, Inc. | Preparation of polymer based powder coatings by ionizing radiation |
US5188693A (en) * | 1986-04-18 | 1993-02-23 | Aishin Kakou K.K. | Process for applying polyvinyl chloride sealing material having low thixotropic index |
GB8813033D0 (en) * | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
US5573771A (en) * | 1988-08-19 | 1996-11-12 | Osteomedical Limited | Medicinal bone mineral products |
US5306500A (en) | 1988-11-21 | 1994-04-26 | Collagen Corporation | Method of augmenting tissue with collagen-polymer conjugates |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
CS277367B6 (en) * | 1990-12-29 | 1993-01-13 | Krajicek Milan | Three-layered vascular prosthesis |
US5541295A (en) * | 1993-02-12 | 1996-07-30 | The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations | Detection of type II collagen and its peptides |
AUPM807094A0 (en) * | 1994-09-09 | 1994-10-06 | Commonwealth Scientific And Industrial Research Organisation | Polymer beads and method for preparation thereof |
US5891558A (en) * | 1994-11-22 | 1999-04-06 | Tissue Engineering, Inc. | Biopolymer foams for use in tissue repair and reconstruction |
US6080194A (en) | 1995-02-10 | 2000-06-27 | The Hospital For Joint Disease Orthopaedic Institute | Multi-stage collagen-based template or implant for use in the repair of cartilage lesions |
GB9503492D0 (en) * | 1995-02-22 | 1995-04-12 | Ed Geistlich S Hne A G F R Che | Chemical product |
GB9721585D0 (en) | 1997-10-10 | 1997-12-10 | Geistlich Soehne Ag | Chemical product |
JPH09208611A (en) * | 1996-02-06 | 1997-08-12 | Japan Synthetic Rubber Co Ltd | Phosphor-dispersed, radiation-sensitive composition |
US5929133A (en) * | 1996-02-16 | 1999-07-27 | Hitachi Chemical Filtec, Inc. | Anti-bacterial film suitable for food packaging |
US5842477A (en) * | 1996-02-21 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Method for repairing cartilage |
US6352558B1 (en) * | 1996-02-22 | 2002-03-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damage joint |
DE19654884C2 (en) | 1996-03-04 | 1999-07-29 | Kirsch Axel | Molded body |
DE19628849C2 (en) | 1996-07-17 | 2002-10-17 | Eads Deutschland Gmbh | Acoustic directional emitter through modulated ultrasound |
US5980347A (en) * | 1996-07-25 | 1999-11-09 | Jsr Corporation | Process for manufacturing plasma display panel |
US5759190A (en) * | 1996-08-30 | 1998-06-02 | Vts Holdings Limited | Method and kit for autologous transplantation |
US5866312A (en) * | 1997-06-19 | 1999-02-02 | Eastman Kodak Company | Photographic element having surface protective layer |
US6221109B1 (en) * | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
-
1995
- 1995-02-22 GB GBGB9503492.2A patent/GB9503492D0/en active Pending
-
1996
- 1996-02-22 CA CA002213533A patent/CA2213533C/en not_active Expired - Fee Related
- 1996-02-22 AT AT96903128T patent/ATE265240T1/en active
- 1996-02-22 JP JP52549796A patent/JP3643381B2/en not_active Expired - Fee Related
- 1996-02-22 ES ES96903128T patent/ES2217304T3/en not_active Expired - Lifetime
- 1996-02-22 DE DE69632313T patent/DE69632313T2/en not_active Expired - Lifetime
- 1996-02-22 EP EP96903128A patent/EP0810888B1/en not_active Expired - Lifetime
- 1996-02-22 WO PCT/GB1996/000399 patent/WO1996025961A1/en active IP Right Grant
- 1996-02-22 US US08/894,517 patent/US6326029B1/en not_active Expired - Lifetime
-
2001
- 2001-11-09 US US09/986,757 patent/US6676969B2/en not_active Expired - Fee Related
- 2001-11-20 US US09/988,805 patent/US7208177B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990005755A1 (en) * | 1988-11-21 | 1990-05-31 | Collagen Corporation | Collagen-polymer conjugates |
WO1990013302A1 (en) * | 1989-04-28 | 1990-11-15 | Brigham And Women's Hospital | Novel materials and methods for guided tissue regeneration |
WO1992013565A1 (en) * | 1991-01-31 | 1992-08-20 | Shaw, Robert, Francis | Growth factor containing matrix for the treatment of cartilage lesions |
FR2679778A1 (en) * | 1991-08-02 | 1993-02-05 | Coletica | Use of collagen cross-linked with a cross-linking agent, for the manufacture of a biocompatible suturable membrane affording slow resorption, as well as such a membrane |
WO1993010722A2 (en) * | 1991-11-26 | 1993-06-10 | Research Development Foundation | Fetal membrane tubes for nerve and vessel grafts |
WO1993011723A1 (en) * | 1991-12-17 | 1993-06-24 | Regen Biologics, Inc. | Prosthetic articular cartilage |
WO1993019168A1 (en) * | 1992-03-18 | 1993-09-30 | Mount Sinai Hospital Corporation | Reconstituted cartilage tissue |
WO1995018638A1 (en) * | 1994-01-06 | 1995-07-13 | Ed Geistlich Sohne Ag Fur Chemische Industrie | Membrane |
Cited By (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7208177B2 (en) | 1995-02-22 | 2007-04-24 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix for reconstruction of cartilage |
US6352558B1 (en) | 1996-02-22 | 2002-03-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damage joint |
US7137989B2 (en) | 1996-08-30 | 2006-11-21 | Verigen Ag | Method, instruments, and kit for autologous transplantation |
US7048750B2 (en) | 1996-08-30 | 2006-05-23 | Verigen Ag | Method, instruments, and kits for autologous transplantation |
US6599301B2 (en) | 1996-08-30 | 2003-07-29 | Verrgen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6599300B2 (en) | 1996-08-30 | 2003-07-29 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6592598B2 (en) | 1996-08-30 | 2003-07-15 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6592599B2 (en) | 1996-08-30 | 2003-07-15 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6569172B2 (en) | 1996-08-30 | 2003-05-27 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US6379367B1 (en) | 1996-08-30 | 2002-04-30 | Verigen Transplantation Service International (Vtsi) Ag | Method instruments and kit for autologous transplantation |
EP1374857A1 (en) * | 1997-01-15 | 2004-01-02 | DePuy Acromed, Inc. | Collagen-polysaccharide matrix for bone and cartilage repair |
EP0994694A4 (en) * | 1997-01-15 | 2002-07-10 | Orquest Inc | Collagen-polysaccharide matrix for bone and cartilage repair |
EP0994694A1 (en) * | 1997-01-15 | 2000-04-26 | Orquest, Inc. | Collagen-polysaccharide matrix for bone and cartilage repair |
US6306169B1 (en) | 1997-03-07 | 2001-10-23 | Abonetics Ltd. | Tissue implant |
WO1998040111A1 (en) * | 1997-03-07 | 1998-09-17 | University College London | Tissue implant |
CZ297205B6 (en) * | 1997-10-10 | 2006-10-11 | Ed Geistlich Söhne Ag Für Chemische Industrie | Process for producing multi-layer membrane, multi-layer membrane per se and use thereof |
WO1999019005A1 (en) * | 1997-10-10 | 1999-04-22 | Ed Geistlich Söhne Ag Für Chemische Industrie | Membrane for use in guided tissue regeneration |
JP4819995B2 (en) * | 1997-10-10 | 2011-11-24 | エド・ガイストリヒ・ゼーネ・アクチエンゲゼルシャフト・フューア・ヒェーミシェ・インドゥストリー | Membrane used to induce tissue regeneration |
US9034315B2 (en) | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
US8911763B2 (en) | 1997-10-10 | 2014-12-16 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material and method |
US6752834B2 (en) | 1997-10-10 | 2004-06-22 | Ed Geistlich Soehne Ag Fuer Chemische Industrie | Membrane for in guided tissue regeneration |
JP2001519210A (en) * | 1997-10-10 | 2001-10-23 | エド・ガイストリヒ・ゼーネ・アクチエンゲゼルシャフト・フューア・ヒェーミシェ・インドゥストリー | Membrane used for tissue regeneration induction |
US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US6866668B2 (en) | 1998-08-14 | 2005-03-15 | Verigen Transplantation Service International (“VTSL”) AG | Methods, instruments and materials for chondrocyte cell transplantation |
US7141072B2 (en) | 1998-10-05 | 2006-11-28 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering |
JP2002527402A (en) * | 1998-10-14 | 2002-08-27 | オークエスト インコーポレイテッド | A method for inducing or enhancing cartilage formation with an extracellular matrix containing GDF-5. |
US6221109B1 (en) | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
WO2001025403A3 (en) * | 1999-10-01 | 2001-11-08 | Consorzio Per Gli Studi Uni | Bio-artificial substrate for the production of animal and, in particular, human tissues and organs |
WO2001025403A2 (en) * | 1999-10-01 | 2001-04-12 | Consorzio Per Gli Studi Universitari | Bio-artificial substrate for the production of animal and, in particular, human tissues and organs |
US6623963B1 (en) | 1999-12-20 | 2003-09-23 | Verigen Ag | Cellular matrix |
WO2001045764A1 (en) * | 1999-12-20 | 2001-06-28 | Verigen Transplantation Service International Ag | Cellular matrix |
WO2001054735A2 (en) * | 2000-01-28 | 2001-08-02 | Orthogene, Inc. | Gel-infused sponges for tissue repair and augmentation |
WO2001054735A3 (en) * | 2000-01-28 | 2001-12-20 | Orthogene Inc | Gel-infused sponges for tissue repair and augmentation |
FR2812553A1 (en) * | 2000-07-19 | 2002-02-08 | Geistlich Soehne Ag | Bone mineral product and collagen combination for repair of injured joints has porous bone mineral particles derived from natural bone having a crystal structure that of natural bone and being free from all endogenous organic material |
US6576015B2 (en) | 2000-07-19 | 2003-06-10 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Bone material and collagen combination for repair of injured joints |
ES2195731A1 (en) * | 2000-07-19 | 2003-12-01 | Geistlich Soehne Ag | Bone material and collagen combination for repair of injured joints |
NL1018560C2 (en) | 2000-07-19 | 2003-08-19 | Geistlich Soehne Ag | Combination of bone material and collagen for repairing damaged joints. |
US6713085B2 (en) | 2001-04-27 | 2004-03-30 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method and membrane for mucosa regeneration |
WO2002089866A1 (en) * | 2001-05-03 | 2002-11-14 | Stichting Katholieke Universiteit | Type ii collagen matricwes for use in cartilage engineering |
EP1254670A1 (en) * | 2001-05-03 | 2002-11-06 | Stichting Katholieke Universiteit | Type II collagen matrices for use in cartilage engineering |
US6444222B1 (en) | 2001-05-08 | 2002-09-03 | Verigen Transplantation Services International Ag | Reinforced matrices |
EP1416879A2 (en) * | 2001-07-16 | 2004-05-12 | Depuy Products, Inc. | Unitary surgical device and method |
EP1416879A4 (en) * | 2001-07-16 | 2007-04-25 | Depuy Products Inc | Unitary surgical device and method |
EP1416888A4 (en) * | 2001-07-16 | 2007-04-25 | Depuy Products Inc | Meniscus regeneration device and method |
EP1416888A2 (en) * | 2001-07-16 | 2004-05-12 | Depuy Products, Inc. | Meniscus regeneration device and method |
EP1312383A3 (en) * | 2001-11-20 | 2003-10-15 | Ed Geistlich Söhne AG Für Chemische Industrie | Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage |
EP1312383A2 (en) * | 2001-11-20 | 2003-05-21 | Ed Geistlich Söhne AG Für Chemische Industrie | Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage |
US8354119B2 (en) | 2001-11-20 | 2013-01-15 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage |
DE10349722A1 (en) * | 2003-10-23 | 2005-06-16 | Beschorner, Katharina, Dr. | Composition for arthritis / arthritis treatment, in particular of joints |
WO2005039528A2 (en) | 2003-10-23 | 2005-05-06 | Katharina Beschorner | Composition for the treatment of arthrosis/arthritis, especially for treating joints |
US7429241B2 (en) | 2005-09-29 | 2008-09-30 | Codman & Shurtleff, Inc. | Dural graft and method of preparing the same |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
WO2008154888A2 (en) | 2007-06-21 | 2008-12-24 | Hypro Otrokovice S.R.O. | Procedure for the manufacture of a structured multilayer membrane, the structured multilayer membrane and its uses |
EP2872071A4 (en) * | 2012-07-11 | 2016-04-20 | Osiris Therapeutics Inc | Methods of manufacturing cartilage products |
US10874763B2 (en) | 2012-07-11 | 2020-12-29 | Osiris Therapeutics, Inc. | Porated cartilage products |
US11406735B2 (en) | 2012-07-11 | 2022-08-09 | Osiris Therapeutics, Inc. | Methods of manufacturing cartilage products |
US11413373B2 (en) | 2012-07-11 | 2022-08-16 | Osiris Therapeutics, Inc. | Disrupted cartilage products |
EP3043805A4 (en) * | 2013-09-09 | 2017-05-31 | Eran Rosines | Biologic prosthesis and methods of production and use |
US10016528B2 (en) | 2013-09-09 | 2018-07-10 | Eran Rosines | Biologic prosthesis and methods of production and use |
US10814035B2 (en) | 2013-09-09 | 2020-10-27 | Eran Rosines | Biological prosthesis and methods of production and use |
US11801330B2 (en) | 2013-09-09 | 2023-10-31 | Rosivo Llc | Biological prosthesis and methods of production and use |
CN112154247A (en) * | 2018-05-03 | 2020-12-29 | C.M.I.铰链机械工业有限公司 | Hinge device for refrigerator and furniture |
CN113398338A (en) * | 2021-06-30 | 2021-09-17 | 华东理工大学 | Double-layer repairing film for guiding tissue regeneration and preparation method thereof |
CN113398338B (en) * | 2021-06-30 | 2022-08-09 | 华东理工大学 | Double-layer repairing film for guiding tissue regeneration and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
ATE265240T1 (en) | 2004-05-15 |
GB9503492D0 (en) | 1995-04-12 |
US6326029B1 (en) | 2001-12-04 |
US6676969B2 (en) | 2004-01-13 |
US20020090391A1 (en) | 2002-07-11 |
JP3643381B2 (en) | 2005-04-27 |
US20020048595A1 (en) | 2002-04-25 |
US7208177B2 (en) | 2007-04-24 |
EP0810888A1 (en) | 1997-12-10 |
JPH11503338A (en) | 1999-03-26 |
CA2213533C (en) | 2008-04-29 |
DE69632313T2 (en) | 2004-09-09 |
EP0810888B1 (en) | 2004-04-28 |
CA2213533A1 (en) | 1996-08-29 |
ES2217304T3 (en) | 2004-11-01 |
DE69632313D1 (en) | 2004-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2213533C (en) | Resorbable extracellular matrix for reconstruction of cartilage tissue | |
CA2412012C (en) | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage | |
JP4064435B2 (en) | Collagen gel and method for producing the same | |
US7892572B2 (en) | Orthopaedic materials derived from keratin | |
WO2002089774A1 (en) | Reinforced matrices | |
CA2419620C (en) | Resorbable extracellular matrix for reconstruction of bone | |
US8858981B2 (en) | Bone healing material comprising matrix carrying bone-forming cells | |
RU2342162C1 (en) | Method for bone tissue biomaterial obtaining, and material for osteoplasty and tissue engineering obtained by such method | |
CN113301928B (en) | Biological scaffolds and methods for making same | |
JPH0326616B2 (en) | ||
KR20050023298A (en) | Orthopaedic materials derived from keratin | |
AU2007254593A1 (en) | Resorbable Extracellular Matrix for Reconstruction of Bone | |
AU2012200086A1 (en) | Resorbable Extracellular Matrix for Reconstruction of Bone | |
AU2002340826A1 (en) | Reinforced matrices | |
BG109565A (en) | Multilayer bioresorbable membrane for guided tissue regeneration |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): CA JP US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2213533 Country of ref document: CA Ref country code: CA Ref document number: 2213533 Kind code of ref document: A Format of ref document f/p: F |
|
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 1996 525497 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1996903128 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 08894517 Country of ref document: US |
|
WWP | Wipo information: published in national office |
Ref document number: 1996903128 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 1996903128 Country of ref document: EP |