WO1997011680A3 - Hormone replacement therapy method and hormone dispenser - Google Patents

Hormone replacement therapy method and hormone dispenser Download PDF

Info

Publication number
WO1997011680A3
WO1997011680A3 PCT/EP1996/004261 EP9604261W WO9711680A3 WO 1997011680 A3 WO1997011680 A3 WO 1997011680A3 EP 9604261 W EP9604261 W EP 9604261W WO 9711680 A3 WO9711680 A3 WO 9711680A3
Authority
WO
WIPO (PCT)
Prior art keywords
dispenser
estrogen
progestogen
hormone
replacement therapy
Prior art date
Application number
PCT/EP1996/004261
Other languages
French (fr)
Other versions
WO1997011680A2 (en
Inventor
Joerg Elliesen
Jutta Riedl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24134029&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1997011680(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to DE69630968T priority Critical patent/DE69630968T2/en
Priority to BR9610915A priority patent/BR9610915A/en
Priority to IL12369196A priority patent/IL123691A/en
Priority to JP9513154A priority patent/JPH11512703A/en
Priority to AT96934493T priority patent/ATE255406T1/en
Application filed by Schering Ag filed Critical Schering Ag
Priority to EP96934493A priority patent/EP0854705B1/en
Priority to PL96325978A priority patent/PL185848B1/en
Priority to AU72827/96A priority patent/AU714084B2/en
Priority to DK96934493T priority patent/DK0854705T3/en
Publication of WO1997011680A2 publication Critical patent/WO1997011680A2/en
Publication of WO1997011680A3 publication Critical patent/WO1997011680A3/en
Priority to NO19981412A priority patent/NO320491B1/en
Priority to HK99102005A priority patent/HK1016887A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/0005—Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container
    • B65D83/0011—Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container moved by a screw-shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D35/00—Pliable tubular containers adapted to be permanently or temporarily deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid material; Holders therefor
    • B65D35/22—Pliable tubular containers adapted to be permanently or temporarily deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid material; Holders therefor with two or more compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/325—Containers having parallel or coaxial compartments, provided with a piston or a movable bottom for discharging contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/0005—Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container

Abstract

Varying the daily dose of either or both of the estrogen and the progestogen administered for hormone replacement therapy (HRT) is readily and inexpensively accomplished, without the necessity of the physician prescribing a new product each time the daily dose of the estrogen or progestogen is changed, by administering preferably transdermally the estrogen and progestogen contained in separate extrudable pharmaceutical compositions from a dispenser which contains means, preferably adjustable only by the attending physician or dispensing pharmacist, for varying the volume of either or both of the respective compositions which is dispensed as a single dose from the dispenser in response to a defined digital dispensing manipulation of the dispenser, thereby facilitating optimal compliance to a combination HRT with individually adjusted dosages of the estrogen and progestogen.
PCT/EP1996/004261 1995-09-28 1996-09-30 Hormone replacement therapy method and hormone dispenser WO1997011680A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DK96934493T DK0854705T3 (en) 1995-09-28 1996-09-30 Dispensing hormone replacement therapy
PL96325978A PL185848B1 (en) 1995-09-28 1996-09-30 Method of performing hormonal substitutive therapy and hormone dispenser therefor
IL12369196A IL123691A (en) 1995-09-28 1996-09-30 Dispenser for estrogen and progestogen
JP9513154A JPH11512703A (en) 1995-09-28 1996-09-30 Hormone replacement therapy and hormone dispensers
AT96934493T ATE255406T1 (en) 1995-09-28 1996-09-30 HORMONE DONOR FOR HORMONE REPLACEMENT THERAPY
DE69630968T DE69630968T2 (en) 1995-09-28 1996-09-30 HORMONE DISPENSER FOR HORMONE REPLACEMENT THERAPY
EP96934493A EP0854705B1 (en) 1995-09-28 1996-09-30 Hormone dispenser for hormone replacement therapy method
BR9610915A BR9610915A (en) 1995-09-28 1996-09-30 Hormone replacement therapy method and hormone dispenser
AU72827/96A AU714084B2 (en) 1995-09-28 1996-09-30 Hormone replacement therapy method and hormone dispenser
NO19981412A NO320491B1 (en) 1995-09-28 1998-03-27 Hormone replacement and hormone dispensing procedures
HK99102005A HK1016887A1 (en) 1995-09-28 1999-05-04 Hormone replacement therapy method and hormone dispenser.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53540295A 1995-09-28 1995-09-28
US08/535,402 1995-09-28

Publications (2)

Publication Number Publication Date
WO1997011680A2 WO1997011680A2 (en) 1997-04-03
WO1997011680A3 true WO1997011680A3 (en) 1997-04-24

Family

ID=24134029

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/004261 WO1997011680A2 (en) 1995-09-28 1996-09-30 Hormone replacement therapy method and hormone dispenser

Country Status (24)

Country Link
US (2) US5922349A (en)
EP (1) EP0854705B1 (en)
JP (1) JPH11512703A (en)
KR (1) KR20000004898A (en)
CN (1) CN1158206C (en)
AT (1) ATE255406T1 (en)
AU (1) AU714084B2 (en)
BR (1) BR9610915A (en)
CA (1) CA2232621A1 (en)
CZ (1) CZ95598A3 (en)
DE (1) DE69630968T2 (en)
DK (1) DK0854705T3 (en)
ES (1) ES2211983T3 (en)
HK (1) HK1016887A1 (en)
HU (1) HUP9802608A3 (en)
IL (1) IL123691A (en)
MX (1) MX9802370A (en)
NO (1) NO320491B1 (en)
PL (1) PL185848B1 (en)
PT (1) PT854705E (en)
TR (1) TR199800560T1 (en)
TW (1) TW329389B (en)
WO (1) WO1997011680A2 (en)
ZA (1) ZA968227B (en)

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Also Published As

Publication number Publication date
US5922349A (en) 1999-07-13
DK0854705T3 (en) 2004-04-13
HK1016887A1 (en) 1999-11-12
EP0854705B1 (en) 2003-12-03
TR199800560T1 (en) 1998-06-22
ES2211983T3 (en) 2004-07-16
HUP9802608A3 (en) 1999-07-28
ZA968227B (en) 1997-07-21
AU7282796A (en) 1997-04-17
KR20000004898A (en) 2000-01-25
JPH11512703A (en) 1999-11-02
AU714084B2 (en) 1999-12-16
NO320491B1 (en) 2005-12-12
NO981412L (en) 1998-05-12
PL325978A1 (en) 1998-08-17
CN1198093A (en) 1998-11-04
NO981412D0 (en) 1998-03-27
PL185848B1 (en) 2003-08-29
IL123691A0 (en) 1998-10-30
CZ95598A3 (en) 1999-06-16
TW329389B (en) 1998-04-11
PT854705E (en) 2004-04-30
HUP9802608A2 (en) 1999-02-01
WO1997011680A2 (en) 1997-04-03
CN1158206C (en) 2004-07-21
DE69630968T2 (en) 2004-10-21
CA2232621A1 (en) 1997-04-03
MX9802370A (en) 1998-08-30
ATE255406T1 (en) 2003-12-15
US5897539A (en) 1999-04-27
EP0854705A2 (en) 1998-07-29
BR9610915A (en) 1999-03-30
IL123691A (en) 2001-10-31
DE69630968D1 (en) 2004-01-15

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