WO1997020198A3 - Method and apparatus for automated image analysis of biological specimens - Google Patents
Method and apparatus for automated image analysis of biological specimens Download PDFInfo
- Publication number
- WO1997020198A3 WO1997020198A3 PCT/US1996/019166 US9619166W WO9720198A3 WO 1997020198 A3 WO1997020198 A3 WO 1997020198A3 US 9619166 W US9619166 W US 9619166W WO 9720198 A3 WO9720198 A3 WO 9720198A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- interest
- objects
- candidate
- images
- color space
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000010191 image analysis Methods 0.000 title 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G01N15/1433—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
- G02B21/244—Devices for focusing using image analysis techniques
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/60—Analysis of geometric attributes
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/693—Acquisition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
- G01N2015/1472—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle with colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1488—Methods for deciding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1497—Particle shape
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9520726A JP2000501184A (en) | 1995-11-30 | 1996-11-27 | Method and apparatus for automatic image analysis of biological specimens |
DE69627183T DE69627183T2 (en) | 1995-11-30 | 1996-11-27 | PROCESS FOR THE AUTOMATIC IMAGE ANALYSIS OF BIOLOGICAL SAMPLES |
EP96940930A EP0864082B1 (en) | 1995-11-30 | 1996-11-27 | Method for automated image analysis of biological specimens |
AT96940930T ATE236386T1 (en) | 1995-11-30 | 1996-11-27 | METHOD FOR AUTOMATIC IMAGE ANALYSIS OF BIOLOGICAL SAMPLES |
AU10869/97A AU724393B2 (en) | 1995-11-30 | 1996-11-27 | Method and apparatus for automated image analysis of biological specimens |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2680595P | 1995-11-30 | 1995-11-30 | |
US60/026,805 | 1995-11-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1997020198A2 WO1997020198A2 (en) | 1997-06-05 |
WO1997020198A3 true WO1997020198A3 (en) | 1997-08-28 |
Family
ID=21833882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/019166 WO1997020198A2 (en) | 1995-11-30 | 1996-11-27 | Method and apparatus for automated image analysis of biological specimens |
Country Status (8)
Country | Link |
---|---|
US (12) | US6215892B1 (en) |
EP (2) | EP1300713A3 (en) |
JP (1) | JP2000501184A (en) |
AT (1) | ATE236386T1 (en) |
AU (1) | AU724393B2 (en) |
CA (1) | CA2236268A1 (en) |
DE (1) | DE69627183T2 (en) |
WO (1) | WO1997020198A2 (en) |
Cited By (3)
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US9235041B2 (en) | 2005-07-01 | 2016-01-12 | Leica Biosystems Imaging, Inc. | System and method for single optical axis multi-detector microscope slide scanner |
US9386211B2 (en) | 2000-05-03 | 2016-07-05 | Leica Biosystems Imaging, Inc. | Fully automatic rapid microscope slide scanner |
US9535243B2 (en) | 2000-05-03 | 2017-01-03 | Leica Biosystems Imaging, Inc. | Optimizing virtual slide image quality |
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US6546123B1 (en) | 2003-04-08 |
CA2236268A1 (en) | 1997-06-05 |
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US6215892B1 (en) | 2001-04-10 |
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EP0864082B1 (en) | 2003-04-02 |
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US7359548B2 (en) | 2008-04-15 |
US6920239B2 (en) | 2005-07-19 |
EP1300713A2 (en) | 2003-04-09 |
EP1300713A3 (en) | 2004-11-03 |
ATE236386T1 (en) | 2003-04-15 |
US20040066960A1 (en) | 2004-04-08 |
US7359536B2 (en) | 2008-04-15 |
US20030228038A1 (en) | 2003-12-11 |
US20050185832A1 (en) | 2005-08-25 |
US20080258061A1 (en) | 2008-10-23 |
US7660449B2 (en) | 2010-02-09 |
US6553135B1 (en) | 2003-04-22 |
US20080260233A1 (en) | 2008-10-23 |
JP2000501184A (en) | 2000-02-02 |
DE69627183T2 (en) | 2004-01-29 |
AU1086997A (en) | 1997-06-19 |
AU724393B2 (en) | 2000-09-21 |
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