WO1998007460A1 - Apparatus for extracting fluids - Google Patents
Apparatus for extracting fluids Download PDFInfo
- Publication number
- WO1998007460A1 WO1998007460A1 PCT/EP1997/004382 EP9704382W WO9807460A1 WO 1998007460 A1 WO1998007460 A1 WO 1998007460A1 EP 9704382 W EP9704382 W EP 9704382W WO 9807460 A1 WO9807460 A1 WO 9807460A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- placenta
- pressure
- supporting surface
- membrane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150038—Source of blood for blood from umbilical cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150045—Source of blood for blood from vagina, placenta, colon or mouth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/14—Female reproductive, genital organs
- A61M2210/1433—Uterus
- A61M2210/1458—Placenta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/14—Female reproductive, genital organs
- A61M2210/1433—Uterus
- A61M2210/1466—Umbilical cord
Definitions
- the present invention relates to an apparatus for extracting fluids, such as blood or other fluids from a placenta or from other human or animal organs or tissues.
- the apparatus according to the invention is used mainly in the biological, medical and veterinary field both for diagnostic and therapeutic purposes and for research purposes, for the extraction of blood or other fluids from the placenta or another organ or tissue to be used subsequently as a source of cells, molecules or other.
- the biological, medical and veterinary fields it is necessary to collect fluids, particularly blood, from organs or tissues or containers in general, both for diagnostic and therapeutic purposes and for research purposes.
- Two non- limitative examples are: 1. the collection of blood from masses of tumoral tissue, since the blood contained in the tumoral tissue is potentially useful for therapeutic purposes after appropriate treatment; 2. the collection of blood from the placenta during childbirth directly after cutting the umbilical cord.
- the blood is useful since it contains stem cells, which are hematopoietic precursor cells, that is to say, cells which are capable of reconstituting the hematopoietic system and therefore can be used, if the need arises, for transplanting to the same donor or to another compatible recipient.
- stem cells which are hematopoietic precursor cells, that is to say, cells which are capable of reconstituting the hematopoietic system and therefore can be used, if the need arises, for transplanting to the same donor or to another compatible recipient.
- the procedures currently used to collect placental blood from an umbilical cord are described hereinafter as a typical example of the recovery of fluids from an organ; it is important to note that the reference to this practice is not limitative and is merely an example of situations in which it is necessary to collect blood or another fluid from tissues, organs or other containers in general.
- Placental blood from the umbilical cord is collected because it contains hematopoietic ste cells which can be used for transplant
- the following conditions must be met: 1. the largest possible amount of blood, that is to say, the highest possible number of cells, must be recovered; 2. the collected blood, which is fetal in origin, must not be contaminated by foreign cell populations, such as for example maternal cells; 3. during collection, contact of the blood with the outside (air or other potentially contaminated objects) must be minimized, or the collection procedure must occur in sterile conditions, possibly in a closed environment; 4. the possibility of human error must be minimized.
- Steps of collection a Before expulsion of the placenta.
- Blood is currently extracted from the placenta in the medical field, both for diagnostic and therapeutic purposes and for research purposes, as follows: during childbirth, directly after the expulsion of the newborn child, the umbilical cord is closed (clamped) in two points and cut in a point which is intermediate between the two closure points. After cutting, the cut end of the umbilical cord which is connected to the placenta protrudes freely from the mother's vagina and is available for collection operations. Typically, blood is collected in the period between the cutting of the umbilical cord and expulsion of the placenta. During this period, the flow of blood is ensured by the pressure generated by uterine contractions, which by compressing the placenta facilitate the outflow of blood through the umbilical cord. b. After expulsion of the placenta.
- Open-circuit systems collect placental blood from the c u t umb i l i c a l co rd i n c o nt a i ne r s wh i c h c o n t a i n anticoagulant . This collection is performed by making the blood flow out directly into the collection container without connecting the end portion of the cord, which is placed loosely at the inlet of the container.
- the main advantage of this system is the absence of resistances to flow, since there are no bottlenecks or sudden decreases in cross-section of the cord and of its vessels .
- a second advantage is that the three vessels which are present in the umbilical cord are simultaneously pervious. Another advantage of the system is the possibility to express the umbilical cord during collection.
- the system inherently (being an "open” system) collects both the blood that flows out of the vessels of the cord and potentially contaminated liquids which flow along the outer surface of the umbilical cord; in particular, the maternal blood which is abundantly present along the outer surface of the placenta flows along the cord and mixes with the blood of the umbilical cord.
- This collection system furthermore exposes the blood to the air of the outside environment, thus facilitating contaminations from microorganisms which are present in the outside environment.
- Another drawback is the constant need for an operator assigned to keeping the umbilical cord in the correct position, particularly if repeated maneuvers for expressing and cleaning the cord are performed.
- Another advantage is reduction of the contamination of the sample with maternal blood or other liquids which flow along the outer surface of the cord.
- the needle inserted in the umbilical vein is not stably fixed to it and can easily come loose, also in view of the highly dynamic nature of childbirth; this problem is particularly felt if collection is continued even after expulsion of the placenta. Accordingly, the continuous presence of an operator is required to ensure the correct placement of the needle during the various steps of collection.
- the flow of blood is hindered by the sudden decrease in cross-section (the needle, no matter how large, can never have the same cross-section as the umbilical vein).
- An aim of the present invention is to provide an apparatus for extracting fluids, particularly blood, from a placenta or another organ or tissue, whether human or animal, both for diagnostic and therapeutic purposes and for research purposes, overcoming the drawbacks of the prior art systems .
- An object of the present invention is to provide an apparatus which does not require particular experience or training for its operation. 5 A further object of the present invention is to provide an apparatus safe in use and free from critical points and risks of error.
- a further object of the present invention is to provide an apparatus enabling a health operator with normal 0 experience of performing the entire procedure without risks.
- Still a further object of the present invention is to provide an apparatus ensuring optimum yield, repeatable over time .
- Still a further object of the present invention is to 5 provide an apparatus that limits contamination of the environment with blood and other potentially infected material .
- Figure 1 is a view of the upper part, meant to apply .uniform or localized, pulsed or continuous mechanical pressure on the maternal surface, hereinafter referenced as the upper surface of the placenta.
- Figure 2 is a view of a rotating lower cone, which is meant to rest and apply uniform or localized, pulsed or continuous mechanical pressure in a radial or centripetal direction on the fetal surface, hereinafter referenced as the lower surface of the placenta, and on the initial portion of the umbilical cord.
- Figure 3 is a view of the supporting membrane made of elastic material, which is meant to provide support and transmit uniform or localized, pulsed or continuous mechanical pressure, generated by the lower cone, in a radial or centripetal or random orientation, to the lower surface of the placenta and to the initial portion of the umbilical cord.
- Figure 4 is a view of the machine body, which is meant to provide support and connect the upper part, the lower resting cone, the supporting membrane, and any mechanical or pneumatic or electric or other elements which are an integral part of the machine.
- Figure 5 is a view of a variation of the lower rotating cone, which is meant to provide support and apply uniform or localized, pulsed or continuous mechanical pressure with a radial or centripetal or random orientation on the lower surface of the placenta and on the initial portion of the umbilical cord.
- Figure 6 is a view of a variation of the lower rotating cone, which is meant to provide support and apply uniform or localized, pulsed or continuous, radial or centripetal or random mechanical pressure on the lower surface of the placenta and on the initial portion of the umbilical cord.
- Figure 7 is a schematic general view of the apparatus for applying pressure to the placenta or organ or tissue and optionally to the proximal portion of the umbilical cord.
- Figure 8 is a section view according to the section line VIII-VIII of Figure 1.
- Figure 9 is a section view according to the section line IX-IX of Figure 2.
- Figure 10 is a section view according to the section line X-X of Figure 5.
- Figure 11 is a section view according to the section line XI-XI of Figure 6.
- the exemplifying and non-limitative description of the apparatus given hereinafter relates to its application to the extraction of blood from the placenta through the umbilical cord after expulsion of the placenta.
- the apparatus according to the invention can of course be used for collecting blood or other fluids even from other organs or tissues.
- the apparatus according to the invention is composed of four parts:
- An upper part 2 suitable to apply uniform or localized, pulsed or continuous mechanical pressure on the upper part of the placenta.
- the upper part of the exemplifying system described here figure 1 is constituted by a hollow surface of suitable size and shape, made of metal or plastic, polymers or other material suitable for the purpose, which is meant to form a cavity 16 which is closed and sealed by virtue of the suitable positioning of a membrane 17 made of an elastic material, which can be rubber, silicone, polymers or other material.
- the pressure inside the chamber is changed and adjusted by means of a manual, electric, mechanical or other system.
- the pressure variation inside the chamber produces curving of the rubber membrane, which can thus assume a concave, plane or convex shape or the shape of an object placed in direct contact therewith.
- the surface of the membrane can be smooth or discontinuous ly shaped and may also have the purpose of transmitting uniform or localized, continuous or pulsed, radially or centripetally orientated mechanical pressure on the upper surface of the placenta, said pressure being generated by means of a suitable device.
- the upper part is connected to the other parts of the machine by virtue of a hinge or joint mechanism or other system 18.
- a locking system 19 of the screw, pin or other type ensures locking of the upper part in the intended position .
- a lower part 3 is adapted to support and apply uniform or localized, pulsed or continuous, radially or centripetally orientated mechanical pressure to the lower surface of the placenta and to the portion of the umbilical cord .
- the lower part of the exemplifying system described herein figure 2 is constituted by a conical or funnel-shaped element 23 of appropriate size which ends, at its apex, with a tube 24 having a cross-section which is suitable to allow the passage of an optional system for connecting the umbilical cord and the collecting container.
- the end tube is in turn inserted and locked in a ball or roller bearing or a bushing, thus allowing the cone to rotate freely about its generating axis.
- the bearing or other system is in turn stably fixed to the machine body by virtue of a suitable support or seat.
- the inner surface of the cone has one or more ridges with a suitable cross-section 25 which have a spiral or helical or epicycloidal arrangement and start in the central region of the cone, proximate to the beginning of the cylindrical or hollow part.
- a second exemplifying and non-limitative variation of the lower part 103, shown in the hypothetical representation of figure 5, is constituted by a series of balls with an eccentric axis or cams which are arranged so as to roll on the supporting membrane and are rigidly coupled to the lower cone by virtue of an appropriately shaped (straight, spiral, etc.) axis.
- This variation ensures a pressure from above which is pulsed and concentrated on the lower surface of the placenta, eliminating radial traction on said placenta.
- Another exemplifying and non-limitative variation 203 shown in figure 6, is constituted by raised portions of suitable size and shape which are suitable to transmit localized and tangentially-orientated pressures to the lower surface of the placenta.
- the lower cone can be made of plastic or metal or other material suitable for this purpose.
- a supporting membrane 4 is made of elastic material, which acts as a surface for support and transmission of uniform or localized, pulsed or continuous, radially or centripetally orientated mechanical pressure on the lower surface of the placenta.
- the supporting membrane (figure 3) in the exemplifying system described herein is constituted by an element 20 which has a round shape and a suitable diameter and thickness, is made of elastic material such as rubber, silicone, polymers or other material suitable for the purpose, and is rigidly coupled to the machine body by virtue of a ring 21.
- an extension of said membrane or a tube 22 made of plastic or other suitable material fixed to the membrane and rigidly coupled to the machine body by virtue of a bracket 28 allows the accommodation and passage of the umbilical cord and of an optional connecting system.
- the membrane is arranged so that it can rest with a suitable tension on the spiral ridge of the lower cone.
- the tension of the membrane is adjusted so as to avoid creating concentrated loads or occlusions of the vessels of the placenta.
- a membrane of suitable consistency and thickness is used.
- the function of the supporting membrane is to transmit the uniform or localized, pulsed or continuous, radially or centripetally or randomly orientated mechanical pressure generated by the movement of the lower cone.
- Another function of the supporting membrane is to eliminate the lateral and tangent traction of said spiral.
- an appropriate lubricant such as talc, oil or other minimizes friction between the membrane and the lower cone.
- a machine body 5 acts as support and connection between the upper part, the lower element, the supporting membrane and any mechanical or pneumatic or electric or other elements which are an integral part of the machine.
- the machine body is constituted by a supporting frame of appropriate shape and size which is made of metal, plastic or other suitable material and has the function of supporting, connecting and positioning the upper part, the lower element, the supporting membrane and the mechanical or pneumatic or electric or other elements which are an integral part of the machine.
- the apparatus described up to now, shown schematically in figure 7, is used to apply pressure to the placenta or organ or tissue when it become available, that is to say, in the case of the placenta, after expulsion.
- the placenta possibly contained in a suitable container with soft walls with an absorbent inner surface and an impermeable outer surface, such as to not hinder drainage and have a containment and protection function, is placed on the supporting membrane 20 so that the maternal surface, hereinafter termed upper surface, is directed upward, and so that the fetal surface, hereinafter termed lower surface, is directed downward.
- the umbilical cord which derives from the lower surface of the placenta, is accommodated, in its initial segment, in the opening of the tube 22 or in the extension of the membrane, whilst its end segment, which has an appropriate length, is connected to a collecting system of the open-circuit or closed-circuit type.
- the ideal configuration provides for the connection of the end segment of the umbilical cord by virtue of a closed-circuit connecting system which does not compress or in any case does not compromise the flow of blood, keeping open all the vessels located in the umbilical cord, and simultaneously ensures isolation of the sample from the outside environment and is practical and safe in use.
- the machine already allows collection of the placental blood by gravity, since an accommodation of this kind allows drainage and does not create occlusions on the surface vessels of the lower part of the placenta.
- the upper part of the machine which has been kept open up to now to allow to position the placenta on the supporting membrane, is closed and fixed by virtue of appropriate systems.
- the pressure applied by the membrane in the inactive position solely by closing the upper part, or the pressure generated by a pneumatic, electric or other system inside the sealed chamber is transmitted to the upper surface of the placenta by means of the elastic membrane 17.
- the drainage effect caused by the position of the placenta is improved by an increase in pressure which is transmitted from the upper surface of the placenta to the internal vessels involved m the drainage.
- a uniform or localized, pulsed or continuous, radially or centripetally or randomly orientated mechanical pressure is applied to the lower surface of the placenta; said pressure is generated by the rotary movement of the spiral of the lower cone 26 or by another system and transmitted through the supporting membrane.
- the fluid extraction system according to the invention is practical, simple and safe to use; the entire operation is brief, does not require particularly training or skill and does not require the constant presence of an operator.
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT97937568T ATE277650T1 (en) | 1996-08-16 | 1997-08-12 | DEVICE FOR EXTRACTING LIQUIDS |
EP97937568A EP0935475B1 (en) | 1996-08-16 | 1997-08-12 | Apparatus for extracting fluids |
AU40147/97A AU4014797A (en) | 1996-08-16 | 1997-08-12 | Apparatus for extracting fluids |
DE69730981T DE69730981T2 (en) | 1996-08-16 | 1997-08-12 | DEVICE FOR EXTRACTING LIQUIDS |
US09/242,422 US6491682B2 (en) | 1996-08-16 | 1997-08-12 | Apparatus for extracting fluids |
JP51035098A JP3949171B2 (en) | 1996-08-16 | 1997-08-12 | Fluid extraction device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUD96A000161 | 1996-08-16 | ||
IT96UD000161A IT1288975B1 (en) | 1996-08-16 | 1996-08-16 | SYSTEM FOR THE EXTRACTION OF FLUIDS |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998007460A1 true WO1998007460A1 (en) | 1998-02-26 |
Family
ID=11422177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1997/004382 WO1998007460A1 (en) | 1996-08-16 | 1997-08-12 | Apparatus for extracting fluids |
Country Status (8)
Country | Link |
---|---|
US (1) | US6491682B2 (en) |
EP (1) | EP0935475B1 (en) |
JP (1) | JP3949171B2 (en) |
AT (1) | ATE277650T1 (en) |
AU (1) | AU4014797A (en) |
DE (1) | DE69730981T2 (en) |
IT (1) | IT1288975B1 (en) |
WO (1) | WO1998007460A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006059958A1 (en) * | 2004-12-01 | 2006-06-08 | National University Of Singapore | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord |
GB2506889A (en) * | 2012-10-10 | 2014-04-16 | Virgin Health Bank Qstp Llc | Collecting placenta and umbilical cord blood |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458109B1 (en) | 1998-08-07 | 2002-10-01 | Hill-Rom Services, Inc. | Wound treatment apparatus |
US6764462B2 (en) | 2000-11-29 | 2004-07-20 | Hill-Rom Services Inc. | Wound treatment apparatus |
US6824533B2 (en) | 2000-11-29 | 2004-11-30 | Hill-Rom Services, Inc. | Wound treatment apparatus |
US20010043943A1 (en) | 2000-05-22 | 2001-11-22 | Coffey Arthur C. | Combination SIS and vacuum bandage and method |
US6855135B2 (en) | 2000-11-29 | 2005-02-15 | Hill-Rom Services, Inc. | Vacuum therapy and cleansing dressing for wounds |
US6685681B2 (en) | 2000-11-29 | 2004-02-03 | Hill-Rom Services, Inc. | Vacuum therapy and cleansing dressing for wounds |
CA2462877A1 (en) | 2001-10-11 | 2003-04-17 | Hill-Rom Services, Inc. | Waste container for negative pressure therapy |
CA2468307A1 (en) | 2001-12-26 | 2003-07-17 | Hill-Rom Services, Inc. | Vacuum bandage packing |
CA2468309A1 (en) | 2001-12-26 | 2003-07-17 | Robert Petrosenko | Wound vacuum therapy dressing kit |
WO2003057070A2 (en) | 2001-12-26 | 2003-07-17 | Hill-Rom Services Inc. | Vented vacuum bandage and method |
US7311690B2 (en) | 2002-02-25 | 2007-12-25 | Novashunt Ag | Implantable fluid management system for the removal of excess fluid |
AU2003223187B2 (en) * | 2002-02-25 | 2008-05-22 | Sequana Medical Ag | Vesicular shunt for the drainage of excess fluid |
WO2003086232A2 (en) | 2002-04-10 | 2003-10-23 | Hill-Rom Services, Inc. | Access openings in vacuum bandage |
JP2005536275A (en) | 2002-08-21 | 2005-12-02 | ヒル−ロム サービシズ,インコーポレイテッド | Wound packing to prevent wound closure |
US7252659B2 (en) * | 2003-02-07 | 2007-08-07 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Implanted surgical drain with sensing and transmitting elements for monitoring internal tissue condition |
JP4411929B2 (en) * | 2003-02-28 | 2010-02-10 | 株式会社日立製作所 | Backup method, system, and program |
DE10310533B4 (en) * | 2003-03-11 | 2005-08-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method and device for obtaining umbilical cord blood |
US8202248B2 (en) | 2004-08-18 | 2012-06-19 | Sequana Medical Ag | Dialysis implant and methods of use |
US8157774B1 (en) | 2006-03-16 | 2012-04-17 | Deka Products Limited Partnership | Apparatus for stem cell collection and methods thereof |
US7654968B1 (en) * | 2006-07-28 | 2010-02-02 | Horvat Branimir L | Placental blood extractor |
JP5414528B2 (en) | 2006-10-31 | 2014-02-12 | セクアナ メディカル エージー | Implantable fluid management device for removing excess fluid |
US8585635B2 (en) | 2012-02-15 | 2013-11-19 | Sequana Medical Ag | Systems and methods for treating chronic liver failure based on peritoneal dialysis |
US10583228B2 (en) | 2015-07-28 | 2020-03-10 | J&M Shuler Medical, Inc. | Sub-atmospheric wound therapy systems and methods |
JP7071338B2 (en) | 2016-08-26 | 2022-05-18 | セクアナ メディカル エヌブイ | Systems and methods for managing and analyzing data generated by embedded devices |
EP3612246B1 (en) | 2017-05-24 | 2020-12-30 | Sequana Medical NV | Direct sodium removal method, solution and apparatus to reduce fluid overload in heart failure patients |
US11559618B2 (en) | 2017-05-24 | 2023-01-24 | Sequana Medical Nv | Formulations and methods for direct sodium removal in patients having severe renal dysfunction |
US11160917B2 (en) | 2020-01-22 | 2021-11-02 | J&M Shuler Medical Inc. | Negative pressure wound therapy barrier |
CN111996117B (en) * | 2020-09-08 | 2022-12-16 | 天晴干细胞股份有限公司 | Placenta blood extraction device and method integrating transportation and collection |
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US5053025A (en) * | 1990-09-04 | 1991-10-01 | Cryo-Cell International, Inc. | Method and apparatus for extracting fluid |
WO1992003180A1 (en) * | 1990-08-27 | 1992-03-05 | Cryo-Cell International, Inc. | Method and apparatus for extracting fluid and related method and apparatus for preserving blood fluid |
US5356373A (en) * | 1991-11-15 | 1994-10-18 | Miles Inc. | Method and apparatus for autologous transfusions in premature infants |
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US4228798A (en) * | 1979-05-01 | 1980-10-21 | Deaton David W | Suction receptacle with hygroscopic filter |
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US5156602A (en) * | 1990-09-05 | 1992-10-20 | Stryker Corporation | Hydrophobic filter protector for wound drainage system |
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1996
- 1996-08-16 IT IT96UD000161A patent/IT1288975B1/en active IP Right Grant
-
1997
- 1997-08-12 EP EP97937568A patent/EP0935475B1/en not_active Expired - Lifetime
- 1997-08-12 US US09/242,422 patent/US6491682B2/en not_active Expired - Fee Related
- 1997-08-12 DE DE69730981T patent/DE69730981T2/en not_active Expired - Fee Related
- 1997-08-12 AT AT97937568T patent/ATE277650T1/en not_active IP Right Cessation
- 1997-08-12 AU AU40147/97A patent/AU4014797A/en not_active Abandoned
- 1997-08-12 WO PCT/EP1997/004382 patent/WO1998007460A1/en active IP Right Grant
- 1997-08-12 JP JP51035098A patent/JP3949171B2/en not_active Expired - Fee Related
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WO1992003180A1 (en) * | 1990-08-27 | 1992-03-05 | Cryo-Cell International, Inc. | Method and apparatus for extracting fluid and related method and apparatus for preserving blood fluid |
US5053025A (en) * | 1990-09-04 | 1991-10-01 | Cryo-Cell International, Inc. | Method and apparatus for extracting fluid |
US5356373A (en) * | 1991-11-15 | 1994-10-18 | Miles Inc. | Method and apparatus for autologous transfusions in premature infants |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006059958A1 (en) * | 2004-12-01 | 2006-06-08 | National University Of Singapore | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord |
EP1819377A1 (en) * | 2004-12-01 | 2007-08-22 | National University of Signapore | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord |
EP1819377A4 (en) * | 2004-12-01 | 2012-12-26 | Univ Singapore | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord |
US8486034B2 (en) | 2004-12-01 | 2013-07-16 | National University Of Singapore | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord |
GB2506889A (en) * | 2012-10-10 | 2014-04-16 | Virgin Health Bank Qstp Llc | Collecting placenta and umbilical cord blood |
WO2014057353A1 (en) * | 2012-10-10 | 2014-04-17 | Virgin Health Bank Qstp-Llc | Apparatus and method for blood collection |
Also Published As
Publication number | Publication date |
---|---|
AU4014797A (en) | 1998-03-06 |
US6491682B2 (en) | 2002-12-10 |
JP2001504360A (en) | 2001-04-03 |
IT1288975B1 (en) | 1998-09-25 |
JP3949171B2 (en) | 2007-07-25 |
ATE277650T1 (en) | 2004-10-15 |
EP0935475A1 (en) | 1999-08-18 |
DE69730981D1 (en) | 2004-11-04 |
ITUD960161A1 (en) | 1998-02-16 |
EP0935475B1 (en) | 2004-09-29 |
DE69730981T2 (en) | 2005-11-17 |
US20010025170A1 (en) | 2001-09-27 |
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