WO1999002956A3 - Method and devices for laser induced fluorescence attenuation spectroscopy (lifas) - Google Patents

Method and devices for laser induced fluorescence attenuation spectroscopy (lifas) Download PDF

Info

Publication number
WO1999002956A3
WO1999002956A3 PCT/US1998/011937 US9811937W WO9902956A3 WO 1999002956 A3 WO1999002956 A3 WO 1999002956A3 US 9811937 W US9811937 W US 9811937W WO 9902956 A3 WO9902956 A3 WO 9902956A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
return light
laser induced
induced fluorescence
devices
Prior art date
Application number
PCT/US1998/011937
Other languages
French (fr)
Other versions
WO1999002956A2 (en
Inventor
Ramez E Shehada
Vasilis Z Marmarelis
Warren S Grundfest
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Priority to AU78306/98A priority Critical patent/AU752061B2/en
Priority to DE69829664T priority patent/DE69829664D1/en
Priority to JP2000502389A priority patent/JP2001509589A/en
Priority to EP98926475A priority patent/EP0995095B1/en
Publication of WO1999002956A2 publication Critical patent/WO1999002956A2/en
Publication of WO1999002956A3 publication Critical patent/WO1999002956A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6402—Atomic fluorescence; Laser induced fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06193—Secundary in-situ sources, e.g. fluorescent particles

Abstract

The Laser Induced Fluorescence Attenuation Spectroscopy method and apparatus include a source (311) adapted to emit modulated radiation that is directed at a sample volume in a sample (314) to produce return light from the sample, a first sensor (321), displaced by a first distance from the sample volume for monitoring the return light and generating a first signal indicative of the intensity of return light, a second sensor (322) displaced by a second distance from the sample volume for monitoring the return light and generating a second signal indicative of the intensity of return light, and a processor (323) adapted to process the first and second signals so as to determine the modulation of the sample. Methods and devices are well-suited for determining the wavelength-dependent attenuation of a sample and using the attenuation to restore the intrinsic laser induced fluorescence thereof, and can be used to determine the ischemic or hypoxic condition of biological tissue.
PCT/US1998/011937 1997-07-07 1998-06-09 Method and devices for laser induced fluorescence attenuation spectroscopy (lifas) WO1999002956A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU78306/98A AU752061B2 (en) 1997-07-07 1998-06-09 Method and devices for laser induced fluorescence attenuation spectroscopy (lifas)
DE69829664T DE69829664D1 (en) 1997-07-07 1998-06-09 METHOD FOR LASER-INDUCED FLUORESCENT DAMPING SPECTROSCOPY
JP2000502389A JP2001509589A (en) 1997-07-07 1998-06-09 Method and apparatus for laser-induced fluorescence decay spectroscopy
EP98926475A EP0995095B1 (en) 1997-07-07 1998-06-09 Method for laser induced fluorescence attenuation spectroscopy (lifas)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/889,017 1997-07-07
US08/889,017 US6124597A (en) 1997-07-07 1997-07-07 Method and devices for laser induced fluorescence attenuation spectroscopy

Publications (2)

Publication Number Publication Date
WO1999002956A2 WO1999002956A2 (en) 1999-01-21
WO1999002956A3 true WO1999002956A3 (en) 1999-04-29

Family

ID=25394356

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/011937 WO1999002956A2 (en) 1997-07-07 1998-06-09 Method and devices for laser induced fluorescence attenuation spectroscopy (lifas)

Country Status (6)

Country Link
US (3) US6124597A (en)
EP (2) EP1562038A3 (en)
JP (1) JP2001509589A (en)
AU (1) AU752061B2 (en)
DE (1) DE69829664D1 (en)
WO (1) WO1999002956A2 (en)

Families Citing this family (416)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9702434A (en) 1991-03-07 1998-05-31 Masimo Corp Signal processing apparatus.
US5490505A (en) 1991-03-07 1996-02-13 Masimo Corporation Signal processing apparatus
US5638818A (en) 1991-03-21 1997-06-17 Masimo Corporation Low noise optical probe
EP1905352B1 (en) 1994-10-07 2014-07-16 Masimo Corporation Signal processing method
US8019400B2 (en) 1994-10-07 2011-09-13 Masimo Corporation Signal processing apparatus
US5758644A (en) 1995-06-07 1998-06-02 Masimo Corporation Manual and automatic probe calibration
US6826422B1 (en) 1997-01-13 2004-11-30 Medispectra, Inc. Spectral volume microprobe arrays
US6229856B1 (en) 1997-04-14 2001-05-08 Masimo Corporation Method and apparatus for demodulating signals in a pulse oximetry system
US6002952A (en) 1997-04-14 1999-12-14 Masimo Corporation Signal processing apparatus and method
US6124597A (en) 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy
JP3667947B2 (en) * 1997-08-29 2005-07-06 富士写真フイルム株式会社 Fluorescence image reader
DE69938493T2 (en) * 1998-01-26 2009-05-20 Massachusetts Institute Of Technology, Cambridge ENDOSCOPE FOR DETECTING FLUORESCENCE IMAGES
US7899518B2 (en) 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US20020091324A1 (en) * 1998-04-06 2002-07-11 Nikiforos Kollias Non-invasive tissue glucose level monitoring
JP2002516689A (en) 1998-06-03 2002-06-11 マシモ・コーポレイション Stereo pulse oximeter
US6721585B1 (en) 1998-10-15 2004-04-13 Sensidyne, Inc. Universal modular pulse oximeter probe for use with reusable and disposable patient attachment devices
USRE41912E1 (en) 1998-10-15 2010-11-02 Masimo Corporation Reusable pulse oximeter probe and disposable bandage apparatus
US7245953B1 (en) 1999-04-12 2007-07-17 Masimo Corporation Reusable pulse oximeter probe and disposable bandage apparatii
US6678541B1 (en) * 1998-10-28 2004-01-13 The Governmemt Of The United States Of America Optical fiber probe and methods for measuring optical properties
US6411838B1 (en) 1998-12-23 2002-06-25 Medispectra, Inc. Systems and methods for optical examination of samples
US6463311B1 (en) 1998-12-30 2002-10-08 Masimo Corporation Plethysmograph pulse recognition processor
US6684090B2 (en) 1999-01-07 2004-01-27 Masimo Corporation Pulse oximetry data confidence indicator
US6587702B1 (en) * 1999-01-22 2003-07-01 Instrumentation Metrics, Inc Classification and characterization of tissue through features related to adipose tissue
US6770028B1 (en) * 1999-01-25 2004-08-03 Masimo Corporation Dual-mode pulse oximeter
US20020140675A1 (en) 1999-01-25 2002-10-03 Ali Ammar Al System and method for altering a display mode based on a gravity-responsive sensor
NZ529432A (en) * 1999-01-26 2005-07-29 Newton Lab Inc Autofluorescence imaging system for endoscopy
US6360114B1 (en) 1999-03-25 2002-03-19 Masimo Corporation Pulse oximeter probe-off detector
DE19922812C2 (en) * 1999-05-19 2001-10-25 Merck Patent Gmbh Measurement of turbidity using reflectometry
US8229549B2 (en) 2004-07-09 2012-07-24 Tyco Healthcare Group Lp Surgical imaging device
US6515273B2 (en) 1999-08-26 2003-02-04 Masimo Corporation System for indicating the expiration of the useful operating life of a pulse oximetry sensor
US6377829B1 (en) 1999-12-09 2002-04-23 Masimo Corporation Resposable pulse oximetry sensor
US6950687B2 (en) 1999-12-09 2005-09-27 Masimo Corporation Isolation and communication element for a resposable pulse oximetry sensor
US20020007122A1 (en) * 1999-12-15 2002-01-17 Howard Kaufman Methods of diagnosing disease
JP2003522578A (en) 2000-02-18 2003-07-29 アーゴス インク Generation of spatially averaged excitation-emission maps in heterogeneous tissue
JP2003522577A (en) * 2000-02-18 2003-07-29 アーゴス インク Multivariate analysis of green and ultraviolet spectra of cell and tissue samples
US6377841B1 (en) 2000-03-31 2002-04-23 Vanderbilt University Tumor demarcation using optical spectroscopy
ATE422325T1 (en) * 2000-03-31 2009-02-15 Koninkl Philips Electronics Nv METHOD AND DEVICE FOR LOCALIZING A DIFFERENT AREA IN A TURBID MEDIUM
AU6501201A (en) 2000-06-01 2001-12-11 Science Applic Int Corp Systems and methods for monitoring health and delivering drugs transdermally
US6430525B1 (en) 2000-06-05 2002-08-06 Masimo Corporation Variable mode averager
ATE434970T1 (en) 2000-08-18 2009-07-15 Masimo Corp TWO-MODE PULSE OXIMETER
US20030020030A1 (en) * 2000-09-22 2003-01-30 Toshio Harada Concentration measurer
IL138683A0 (en) 2000-09-25 2001-10-31 Vital Medical Ltd Apparatus and method for monitoring tissue vitality parameters
US6839661B2 (en) * 2000-12-15 2005-01-04 Medispectra, Inc. System for normalizing spectra
US7142306B2 (en) * 2001-01-23 2006-11-28 Schlumberger Technology Corporation Optical probes and probe systems for monitoring fluid flow in a well
US6704109B2 (en) * 2001-01-23 2004-03-09 Schlumberger Technology Corporation Downhole fluorescence detection apparatus
US7139598B2 (en) * 2002-04-04 2006-11-21 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US20070276199A1 (en) * 2002-04-04 2007-11-29 Ediger Marwood N Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence
DE60227162D1 (en) * 2001-04-20 2008-07-31 Power Med Interventions Inc ILLUSTRATION DEVICE
ES2381407T3 (en) 2001-04-20 2012-05-28 Tyco Healthcare Group Lp Bipolar or ultrasonic surgical device
US6796710B2 (en) * 2001-06-08 2004-09-28 Ethicon Endo-Surgery, Inc. System and method of measuring and controlling temperature of optical fiber tip in a laser system
US6850787B2 (en) 2001-06-29 2005-02-01 Masimo Laboratories, Inc. Signal component processor
US6697658B2 (en) 2001-07-02 2004-02-24 Masimo Corporation Low power pulse oximeter
WO2003032808A2 (en) 2001-10-15 2003-04-24 University Of Massachusetts Tissue oxygen measurement system
US7211377B1 (en) 2002-01-22 2007-05-01 Microbiosystems, Limited Partnership Method for detecting the presence of dormant cryptobiotic microorganisms
US7186990B2 (en) * 2002-01-22 2007-03-06 Microbiosystems, Limited Partnership Method and apparatus for detecting and imaging the presence of biological materials
US6750006B2 (en) 2002-01-22 2004-06-15 Microbiosystems, Limited Partnership Method for detecting the presence of microbes and determining their physiological status
US7355512B1 (en) 2002-01-24 2008-04-08 Masimo Corporation Parallel alarm processor
DE60336303D1 (en) 2002-01-30 2011-04-21 Tyco Healthcare SURGICAL IMAGING DEVICE
IL148795A0 (en) 2002-03-20 2002-09-12 Vital Medical Ltd Apparatus and method for monitoring tissue vitality parameters for the diagnosis of body metabolic emergency state
US6850788B2 (en) 2002-03-25 2005-02-01 Masimo Corporation Physiological measurement communications adapter
US8140147B2 (en) * 2002-04-04 2012-03-20 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using a flexible probe to determine tissue fluorescence of various sites
US8131332B2 (en) * 2002-04-04 2012-03-06 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites
US20080009689A1 (en) * 2002-04-09 2008-01-10 Benaron David A Difference-weighted somatic spectroscopy
US20070096039A1 (en) * 2002-05-03 2007-05-03 Rakesh Kapoor Evaluation Of Multicomponent Mixtures Using Modulated Light Beams
US20030205682A1 (en) * 2002-05-03 2003-11-06 Rakesh Kapoor Evaluation of multicomponent mixtures using modulated light beams
AU2003259095A1 (en) * 2002-07-09 2004-01-23 Medispectra Inc Methods and apparatus for characterization of tissue samples
US6818903B2 (en) * 2002-07-09 2004-11-16 Medispectra, Inc. Method and apparatus for identifying spectral artifacts
US7103401B2 (en) * 2002-07-10 2006-09-05 Medispectra, Inc. Colonic polyp discrimination by tissue fluorescence and fiberoptic probe
US6768918B2 (en) 2002-07-10 2004-07-27 Medispectra, Inc. Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof
DE60332362D1 (en) 2002-09-30 2010-06-10 Power Medical Interventions Llc INDEPENDENT STERILIZABLE SURGICAL SYSTEM
CN1493250A (en) * 2002-10-31 2004-05-05 ƽ Device using endoscope to diagnose precancer affection
US6970792B1 (en) 2002-12-04 2005-11-29 Masimo Laboratories, Inc. Systems and methods for determining blood oxygen saturation values using complex number encoding
US7919713B2 (en) 2007-04-16 2011-04-05 Masimo Corporation Low noise oximetry cable including conductive cords
US6920345B2 (en) 2003-01-24 2005-07-19 Masimo Corporation Optical sensor including disposable and reusable elements
CN101408459B (en) * 2003-03-31 2012-02-15 佐勒技术公司 Method and device for monitoring and controlling combusting course
DE10315541A1 (en) * 2003-04-04 2004-10-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method of determining the degree of freshness of food products is based on the wavelength and radiation intensity of emitted florescent radiation
US7181219B2 (en) * 2003-05-22 2007-02-20 Lucent Technologies Inc. Wireless handover using anchor termination
US7003338B2 (en) 2003-07-08 2006-02-21 Masimo Corporation Method and apparatus for reducing coupling between signals
US7500950B2 (en) 2003-07-25 2009-03-10 Masimo Corporation Multipurpose sensor port
JP2007500529A (en) * 2003-07-31 2007-01-18 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ Method and apparatus with variable numerical aperture for determining the properties of fluid flowing through a biological tube structure
US7254431B2 (en) 2003-08-28 2007-08-07 Masimo Corporation Physiological parameter tracking system
CN100998499B (en) * 2003-10-28 2013-07-24 薇拉莱特公司 Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US7483729B2 (en) 2003-11-05 2009-01-27 Masimo Corporation Pulse oximeter access apparatus and method
US7587236B2 (en) * 2004-01-08 2009-09-08 Lawrence Livermore National Security, Llc Optical spectroscopy for the detection of ischemic tissue injury
US7438683B2 (en) 2004-03-04 2008-10-21 Masimo Corporation Application identification sensor
JP2007527776A (en) 2004-03-08 2007-10-04 マシモ・コーポレイション Physiological parameter system
JP3721408B2 (en) 2004-04-06 2005-11-30 国立大学法人 岡山大学 Brain ischemia monitoring monitor
CA2464029A1 (en) 2004-04-08 2005-10-08 Valery Telfort Non-invasive ventilation monitor
DE102004024494B4 (en) * 2004-05-16 2019-10-17 Dürr Dental SE Medical camera
US7640046B2 (en) * 2004-06-18 2009-12-29 Cardiac Pacemakers, Inc. Methods and apparatuses for localizing myocardial infarction during catheterization
US7343186B2 (en) 2004-07-07 2008-03-11 Masimo Laboratories, Inc. Multi-wavelength physiological monitor
US9341565B2 (en) 2004-07-07 2016-05-17 Masimo Corporation Multiple-wavelength physiological monitor
US7937128B2 (en) 2004-07-09 2011-05-03 Masimo Corporation Cyanotic infant sensor
US7254429B2 (en) 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
US8036727B2 (en) 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
JP2008522745A (en) * 2004-12-09 2008-07-03 フレキシブル メディカル システムズ， エルエルシー Apparatus and method for continuous real-time tracking biomolecule sampling, analysis, and delivery
US7491943B2 (en) * 2005-01-13 2009-02-17 Whitehead Institute For Biomedical Research Method and apparatus for UV imaging
US20060189871A1 (en) 2005-02-18 2006-08-24 Ammar Al-Ali Portable patient monitor
JP2008531225A (en) 2005-03-01 2008-08-14 マシモ・ラボラトリーズ・インコーポレーテッド Multi-wavelength sensor interconnection
JP2008537903A (en) 2005-04-13 2008-10-02 グルコライト・コーポレーシヨン Data processing and calibration method for blood glucose monitor based on OCT
EP1893975A4 (en) * 2005-06-13 2010-08-04 Stratagene California System and method for fluorescence excitation and detection having distinct optical paths
DE102005045906B4 (en) * 2005-09-26 2007-11-29 Siemens Ag Device for receiving a tissue containing a fluorescent dye
US7962188B2 (en) 2005-10-14 2011-06-14 Masimo Corporation Robust alarm system
US7530942B1 (en) 2005-10-18 2009-05-12 Masimo Corporation Remote sensing infant warmer
US8233955B2 (en) 2005-11-29 2012-07-31 Cercacor Laboratories, Inc. Optical sensor including disposable and reusable elements
US20070180140A1 (en) * 2005-12-03 2007-08-02 Welch James P Physiological alarm notification system
US7847941B2 (en) * 2005-12-07 2010-12-07 Los Alamos National Security, Llc Fiber optical assembly for fluorescence spectrometry
US8333874B2 (en) * 2005-12-09 2012-12-18 Flexible Medical Systems, Llc Flexible apparatus and method for monitoring and delivery
US7990382B2 (en) 2006-01-03 2011-08-02 Masimo Corporation Virtual display
US8182443B1 (en) 2006-01-17 2012-05-22 Masimo Corporation Drug administration controller
US20090306533A1 (en) * 2006-01-26 2009-12-10 Rousche Patrick J Stroke Inducing and Monitoring System and Method for Using the Same
GB0604231D0 (en) * 2006-03-02 2006-04-12 Ucl Biomedica Plc Cancer detection system
US20070244377A1 (en) * 2006-03-14 2007-10-18 Cozad Jenny L Pulse oximeter sleeve
US8219172B2 (en) 2006-03-17 2012-07-10 Glt Acquisition Corp. System and method for creating a stable optical interface
US7846390B2 (en) * 2006-03-30 2010-12-07 King Fahd University Of Petroleum And Minerals Apparatus and method for measuring concentrations of fuel mixtures using depth-resolved laser-induced fluorescence
US9176141B2 (en) 2006-05-15 2015-11-03 Cercacor Laboratories, Inc. Physiological monitor calibration system
US7941199B2 (en) 2006-05-15 2011-05-10 Masimo Laboratories, Inc. Sepsis monitor
US8998809B2 (en) 2006-05-15 2015-04-07 Cercacor Laboratories, Inc. Systems and methods for calibrating minimally invasive and non-invasive physiological sensor devices
WO2007140478A2 (en) 2006-05-31 2007-12-06 Masimo Corporation Respiratory monitoring
US10188348B2 (en) 2006-06-05 2019-01-29 Masimo Corporation Parameter upgrade system
US20080039735A1 (en) * 2006-06-06 2008-02-14 Hickerson Barry L Respiratory monitor display
US20080064965A1 (en) * 2006-09-08 2008-03-13 Jay Gregory D Devices and methods for measuring pulsus paradoxus
US8457707B2 (en) 2006-09-20 2013-06-04 Masimo Corporation Congenital heart disease monitor
US8315683B2 (en) 2006-09-20 2012-11-20 Masimo Corporation Duo connector patient cable
USD614305S1 (en) 2008-02-29 2010-04-20 Masimo Corporation Connector assembly
USD609193S1 (en) 2007-10-12 2010-02-02 Masimo Corporation Connector assembly
US20080103375A1 (en) * 2006-09-22 2008-05-01 Kiani Massi E Patient monitor user interface
US8840549B2 (en) 2006-09-22 2014-09-23 Masimo Corporation Modular patient monitor
US9161696B2 (en) 2006-09-22 2015-10-20 Masimo Corporation Modular patient monitor
US9192329B2 (en) 2006-10-12 2015-11-24 Masimo Corporation Variable mode pulse indicator
US9861305B1 (en) 2006-10-12 2018-01-09 Masimo Corporation Method and apparatus for calibration to reduce coupling between signals in a measurement system
EP2073692B1 (en) 2006-10-12 2017-07-26 Masimo Corporation Perfusion index smoothing
US20080094228A1 (en) * 2006-10-12 2008-04-24 Welch James P Patient monitor using radio frequency identification tags
US8265723B1 (en) 2006-10-12 2012-09-11 Cercacor Laboratories, Inc. Oximeter probe off indicator defining probe off space
DE102006048317A1 (en) * 2006-10-12 2008-04-17 Robert Bosch Gmbh Optical fiber sensor for optical measuring device i.e. interferometric measuring device, has optical fiber modularly provided with mechanically stabilizing coating in area of fiber end piece and/or in area of mechanical receiver
US8255026B1 (en) 2006-10-12 2012-08-28 Masimo Corporation, Inc. Patient monitor capable of monitoring the quality of attached probes and accessories
US7880626B2 (en) 2006-10-12 2011-02-01 Masimo Corporation System and method for monitoring the life of a physiological sensor
US8600467B2 (en) 2006-11-29 2013-12-03 Cercacor Laboratories, Inc. Optical sensor including disposable and reusable elements
JP5441707B2 (en) 2006-12-09 2014-03-12 マシモ コーポレイション Plethysmograph variation processor
US8852094B2 (en) 2006-12-22 2014-10-07 Masimo Corporation Physiological parameter system
US7791155B2 (en) 2006-12-22 2010-09-07 Masimo Laboratories, Inc. Detector shield
US8652060B2 (en) 2007-01-20 2014-02-18 Masimo Corporation Perfusion trend indicator
RU2457466C2 (en) * 2007-02-12 2012-07-27 Конинклейке Филипс Электроникс Н.В. Array-based control device
US8101426B2 (en) * 2007-03-02 2012-01-24 Icyt Mission Technology, Inc. System and method for the measurement of multiple fluorescence emissions in a flow cytometry system
EP2139383B1 (en) 2007-03-27 2013-02-13 Masimo Laboratories, Inc. Multiple wavelength optical sensor
US8374665B2 (en) 2007-04-21 2013-02-12 Cercacor Laboratories, Inc. Tissue profile wellness monitor
US8764671B2 (en) 2007-06-28 2014-07-01 Masimo Corporation Disposable active pulse sensor
US8818477B2 (en) 2007-07-13 2014-08-26 University Of Massachusetts Physical performance monitoring and monitors
US8048040B2 (en) 2007-09-13 2011-11-01 Masimo Corporation Fluid titration system
US8274360B2 (en) 2007-10-12 2012-09-25 Masimo Corporation Systems and methods for storing, analyzing, and retrieving medical data
JP5296793B2 (en) 2007-10-12 2013-09-25 マシモ コーポレイション Connector assembly
US8310336B2 (en) 2008-10-10 2012-11-13 Masimo Corporation Systems and methods for storing, analyzing, retrieving and displaying streaming medical data
US8355766B2 (en) 2007-10-12 2013-01-15 Masimo Corporation Ceramic emitter substrate
US8553337B2 (en) * 2007-11-12 2013-10-08 Cornell University Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods
WO2009064753A1 (en) * 2007-11-12 2009-05-22 Cornell University Non-imaging, weakly focused fluorescence emission apparatus and methods
US8280484B2 (en) 2007-12-18 2012-10-02 The Invention Science Fund I, Llc System, devices, and methods for detecting occlusions in a biological subject
US8636670B2 (en) 2008-05-13 2014-01-28 The Invention Science Fund I, Llc Circulatory monitoring systems and methods
US9672471B2 (en) 2007-12-18 2017-06-06 Gearbox Llc Systems, devices, and methods for detecting occlusions in a biological subject including spectral learning
US20090287120A1 (en) 2007-12-18 2009-11-19 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Circulatory monitoring systems and methods
US9717896B2 (en) 2007-12-18 2017-08-01 Gearbox, Llc Treatment indications informed by a priori implant information
DE202008009859U1 (en) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Device for the optional measurement of in particular luminescence and / or fluorescence radiation
US8571617B2 (en) 2008-03-04 2013-10-29 Glt Acquisition Corp. Flowometry in optical coherence tomography for analyte level estimation
WO2009134724A1 (en) * 2008-05-02 2009-11-05 Masimo Corporation Monitor configuration system
JP2011519684A (en) 2008-05-05 2011-07-14 マシモ コーポレイション Pulse oximeter system with electrical disconnect circuit
DK2291640T3 (en) 2008-05-20 2019-03-11 Univ Health Network Device and method for fluorescence-based imaging and monitoring
USD621516S1 (en) 2008-08-25 2010-08-10 Masimo Laboratories, Inc. Patient monitoring sensor
JP5756752B2 (en) 2008-07-03 2015-07-29 セルカコール・ラボラトリーズ・インコーポレイテッドＣｅｒｃａｃｏｒ Ｌａｂｏｒａｔｏｒｉｅｓ， Ｉｎｃ． Sensor
US8512975B2 (en) 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
US8203438B2 (en) 2008-07-29 2012-06-19 Masimo Corporation Alarm suspend system
US8515509B2 (en) 2008-08-04 2013-08-20 Cercacor Laboratories, Inc. Multi-stream emitter for noninvasive measurement of blood constituents
WO2010031070A2 (en) 2008-09-15 2010-03-18 Masimo Corporation Patient monitor including multi-parameter graphical display
SE532941C2 (en) 2008-09-15 2010-05-18 Phasein Ab Gas sampling line for breathing gases
US8346330B2 (en) 2008-10-13 2013-01-01 Masimo Corporation Reflection-detector sensor position indicator
US8401602B2 (en) 2008-10-13 2013-03-19 Masimo Corporation Secondary-emitter sensor position indicator
US10167494B2 (en) * 2008-10-31 2019-01-01 Biomerieux, Inc. Method for detection, characterization and/or identification of microorganisms in a sealed container
US8771204B2 (en) 2008-12-30 2014-07-08 Masimo Corporation Acoustic sensor assembly
KR101674694B1 (en) 2009-01-09 2016-11-09 졸로 테크놀러지스, 아이엔씨. Method and apparatus for monitoring combustion properties in an interior of a boiler
US8588880B2 (en) 2009-02-16 2013-11-19 Masimo Corporation Ear sensor
US9323894B2 (en) 2011-08-19 2016-04-26 Masimo Corporation Health care sanitation monitoring system
EP3605550A1 (en) 2009-03-04 2020-02-05 Masimo Corporation Medical monitoring system
US10007758B2 (en) 2009-03-04 2018-06-26 Masimo Corporation Medical monitoring system
US10032002B2 (en) 2009-03-04 2018-07-24 Masimo Corporation Medical monitoring system
US8388353B2 (en) 2009-03-11 2013-03-05 Cercacor Laboratories, Inc. Magnetic connector
US20100234718A1 (en) * 2009-03-12 2010-09-16 Anand Sampath Open architecture medical communication system
US8897847B2 (en) 2009-03-23 2014-11-25 Masimo Corporation Digit gauge for noninvasive optical sensor
CA2756225A1 (en) 2009-03-25 2010-09-30 Los Alamos National Security, Llc Fiber optical assembly for fluorescence spectrometry
CA2756071A1 (en) * 2009-03-25 2010-09-30 Los Alamos National Security, Llc Rapid antemortem detection of infectious agents
WO2010135373A1 (en) 2009-05-19 2010-11-25 Masimo Corporation Disposable components for reusable physiological sensor
US8571619B2 (en) 2009-05-20 2013-10-29 Masimo Corporation Hemoglobin display and patient treatment
US8418524B2 (en) 2009-06-12 2013-04-16 Masimo Corporation Non-invasive sensor calibration device
US8670811B2 (en) 2009-06-30 2014-03-11 Masimo Corporation Pulse oximetry system for adjusting medical ventilation
US20110208015A1 (en) * 2009-07-20 2011-08-25 Masimo Corporation Wireless patient monitoring system
US20110040197A1 (en) * 2009-07-20 2011-02-17 Masimo Corporation Wireless patient monitoring system
US8471713B2 (en) 2009-07-24 2013-06-25 Cercacor Laboratories, Inc. Interference detector for patient monitor
US8473020B2 (en) 2009-07-29 2013-06-25 Cercacor Laboratories, Inc. Non-invasive physiological sensor cover
US20110028809A1 (en) * 2009-07-29 2011-02-03 Masimo Corporation Patient monitor ambient display device
US20110028806A1 (en) * 2009-07-29 2011-02-03 Sean Merritt Reflectance calibration of fluorescence-based glucose measurements
US20110087081A1 (en) * 2009-08-03 2011-04-14 Kiani Massi Joe E Personalized physiological monitor
US8688183B2 (en) 2009-09-03 2014-04-01 Ceracor Laboratories, Inc. Emitter driver for noninvasive patient monitor
JP2011053135A (en) * 2009-09-03 2011-03-17 Japan Aerospace Exploration Agency Device and method for multi-wavelength fluorescence imaging for evaluation of biological metabolic function
US20110172498A1 (en) 2009-09-14 2011-07-14 Olsen Gregory A Spot check monitor credit system
US9579039B2 (en) 2011-01-10 2017-02-28 Masimo Corporation Non-invasive intravascular volume index monitor
US9510779B2 (en) 2009-09-17 2016-12-06 Masimo Corporation Analyte monitoring using one or more accelerometers
US20110137297A1 (en) 2009-09-17 2011-06-09 Kiani Massi Joe E Pharmacological management system
US8571618B1 (en) 2009-09-28 2013-10-29 Cercacor Laboratories, Inc. Adaptive calibration system for spectrophotometric measurements
US8401608B2 (en) * 2009-09-30 2013-03-19 Covidien Lp Method of analyzing photon density waves in a medical monitor
US20110082711A1 (en) * 2009-10-06 2011-04-07 Masimo Laboratories, Inc. Personal digital assistant or organizer for monitoring glucose levels
US8430817B1 (en) 2009-10-15 2013-04-30 Masimo Corporation System for determining confidence in respiratory rate measurements
US8790268B2 (en) 2009-10-15 2014-07-29 Masimo Corporation Bidirectional physiological information display
US9106038B2 (en) 2009-10-15 2015-08-11 Masimo Corporation Pulse oximetry system with low noise cable hub
US10463340B2 (en) 2009-10-15 2019-11-05 Masimo Corporation Acoustic respiratory monitoring systems and methods
US8755535B2 (en) 2009-10-15 2014-06-17 Masimo Corporation Acoustic respiratory monitoring sensor having multiple sensing elements
WO2011047216A2 (en) 2009-10-15 2011-04-21 Masimo Corporation Physiological acoustic monitoring system
US9848800B1 (en) 2009-10-16 2017-12-26 Masimo Corporation Respiratory pause detector
WO2011063032A1 (en) * 2009-11-17 2011-05-26 Veralight, Inc. Method and apparatus to detect coronary artery calcification or disease
US9839381B1 (en) 2009-11-24 2017-12-12 Cercacor Laboratories, Inc. Physiological measurement system with automatic wavelength adjustment
GB2487882B (en) 2009-12-04 2017-03-29 Masimo Corp Calibration for multi-stage physiological monitors
US9153112B1 (en) 2009-12-21 2015-10-06 Masimo Corporation Modular patient monitor
DE112011100282T5 (en) 2010-01-19 2012-11-29 Masimo Corporation Wellness assessment system
GB2490832B (en) 2010-03-01 2016-09-21 Masimo Corp Adaptive alarm system
US8584345B2 (en) 2010-03-08 2013-11-19 Masimo Corporation Reprocessing of a physiological sensor
JP2011185842A (en) 2010-03-10 2011-09-22 Fujifilm Corp Method and device for analyzing low oxygen region of biosample by time resolving measurement of light induced self-fluorescence
US9307928B1 (en) 2010-03-30 2016-04-12 Masimo Corporation Plethysmographic respiration processor
US8655807B2 (en) 2010-04-05 2014-02-18 Applied Research Associates, Inc. Methods for forming recognition algorithms for laser-induced breakdown spectroscopy
US9138180B1 (en) 2010-05-03 2015-09-22 Masimo Corporation Sensor adapter cable
US8712494B1 (en) 2010-05-03 2014-04-29 Masimo Corporation Reflective non-invasive sensor
US8666468B1 (en) 2010-05-06 2014-03-04 Masimo Corporation Patient monitor for determining microcirculation state
US9326712B1 (en) 2010-06-02 2016-05-03 Masimo Corporation Opticoustic sensor
US8740792B1 (en) 2010-07-12 2014-06-03 Masimo Corporation Patient monitor capable of accounting for environmental conditions
US9408542B1 (en) 2010-07-22 2016-08-09 Masimo Corporation Non-invasive blood pressure measurement system
WO2012027613A1 (en) 2010-08-26 2012-03-01 Masimo Corporation Blood pressure measurement system
WO2012050847A2 (en) 2010-09-28 2012-04-19 Masimo Corporation Depth of consciousness monitor including oximeter
US9995681B2 (en) * 2010-09-28 2018-06-12 Authentix, Inc. Determining the quantity of a taggant in a liquid sample
US9775545B2 (en) 2010-09-28 2017-10-03 Masimo Corporation Magnetic electrical connector for patient monitors
US9211095B1 (en) 2010-10-13 2015-12-15 Masimo Corporation Physiological measurement logic engine
US8723677B1 (en) 2010-10-20 2014-05-13 Masimo Corporation Patient safety system with automatically adjusting bed
EP2620093A1 (en) * 2010-10-29 2013-07-31 Olympus Corporation Optical measurement device and probe
US20120226117A1 (en) 2010-12-01 2012-09-06 Lamego Marcelo M Handheld processing device including medical applications for minimally and non invasive glucose measurements
US9451913B2 (en) 2010-12-10 2016-09-27 Touchtek Labs, Llc Transdermal sampling and analysis device
US9877673B2 (en) 2010-12-10 2018-01-30 Clinitech, Llc Transdermal sampling and analysis device
EP2673721A1 (en) 2011-02-13 2013-12-18 Masimo Corporation Medical characterization system
US9066666B2 (en) 2011-02-25 2015-06-30 Cercacor Laboratories, Inc. Patient monitor for monitoring microcirculation
US8830449B1 (en) 2011-04-18 2014-09-09 Cercacor Laboratories, Inc. Blood analysis system
US9095316B2 (en) 2011-04-20 2015-08-04 Masimo Corporation System for generating alarms based on alarm patterns
US9622692B2 (en) 2011-05-16 2017-04-18 Masimo Corporation Personal health device
US9532722B2 (en) 2011-06-21 2017-01-03 Masimo Corporation Patient monitoring system
US9986919B2 (en) 2011-06-21 2018-06-05 Masimo Corporation Patient monitoring system
US9245668B1 (en) 2011-06-29 2016-01-26 Cercacor Laboratories, Inc. Low noise cable providing communication between electronic sensor components and patient monitor
US11439329B2 (en) 2011-07-13 2022-09-13 Masimo Corporation Multiple measurement mode in a physiological sensor
US9192351B1 (en) 2011-07-22 2015-11-24 Masimo Corporation Acoustic respiratory monitoring sensor with probe-off detection
US8755872B1 (en) 2011-07-28 2014-06-17 Masimo Corporation Patient monitoring system for indicating an abnormal condition
US9782077B2 (en) 2011-08-17 2017-10-10 Masimo Corporation Modulated physiological sensor
WO2013044182A1 (en) 2011-09-22 2013-03-28 The George Washington University Systems and methods for visualizing ablated tissue
US9014789B2 (en) 2011-09-22 2015-04-21 The George Washington University Systems and methods for visualizing ablated tissue
US9436645B2 (en) 2011-10-13 2016-09-06 Masimo Corporation Medical monitoring hub
US9943269B2 (en) 2011-10-13 2018-04-17 Masimo Corporation System for displaying medical monitoring data
EP2765909B1 (en) 2011-10-13 2019-06-26 Masimo Corporation Physiological acoustic monitoring system
US9808188B1 (en) 2011-10-13 2017-11-07 Masimo Corporation Robust fractional saturation determination
US9778079B1 (en) 2011-10-27 2017-10-03 Masimo Corporation Physiological monitor gauge panel
JP5970785B2 (en) * 2011-11-16 2016-08-17 ソニー株式会社 Biological measuring device, biological measuring method, program, and recording medium
US9968284B2 (en) 2011-12-02 2018-05-15 Clinitech, Llc Anti-interferent barrier layers for non-invasive transdermal sampling and analysis device
US9445759B1 (en) 2011-12-22 2016-09-20 Cercacor Laboratories, Inc. Blood glucose calibration system
US11172890B2 (en) 2012-01-04 2021-11-16 Masimo Corporation Automated condition screening and detection
US9392945B2 (en) 2012-01-04 2016-07-19 Masimo Corporation Automated CCHD screening and detection
US10307111B2 (en) 2012-02-09 2019-06-04 Masimo Corporation Patient position detection system
US10149616B2 (en) 2012-02-09 2018-12-11 Masimo Corporation Wireless patient monitoring device
US9480435B2 (en) 2012-02-09 2016-11-01 Masimo Corporation Configurable patient monitoring system
EP2845086B1 (en) 2012-03-25 2021-12-22 Masimo Corporation Physiological monitor touchscreen interface
JP6490577B2 (en) 2012-04-17 2019-03-27 マシモ・コーポレイション How to operate a pulse oximeter device
KR101994509B1 (en) 2012-04-19 2019-06-28 존 징크 컴파니 엘엘씨 In-Furnace Retro-Reflectors with Steerable Tunable Diode Laser Absorption Spectrometer
RU2511262C2 (en) * 2012-05-29 2014-04-10 Общество с ограниченной ответственностью "Научно-производственный центр медицинских и промышленных биотехнологий Спектролюкс" Method for monitoring of treatment of disease involving fluorescence diagnostics of disease, and device for implementing it
US10542903B2 (en) 2012-06-07 2020-01-28 Masimo Corporation Depth of consciousness monitor
US20160112684A1 (en) * 2013-05-23 2016-04-21 Medibotics Llc Spectroscopic Finger Ring for Compositional Analysis of Food or Other Environmental Objects
US9697928B2 (en) 2012-08-01 2017-07-04 Masimo Corporation Automated assembly sensor cable
US10827961B1 (en) 2012-08-29 2020-11-10 Masimo Corporation Physiological measurement calibration
US9749232B2 (en) 2012-09-20 2017-08-29 Masimo Corporation Intelligent medical network edge router
US9877650B2 (en) 2012-09-20 2018-01-30 Masimo Corporation Physiological monitor with mobile computing device connectivity
US9955937B2 (en) 2012-09-20 2018-05-01 Masimo Corporation Acoustic patient sensor coupler
US9717458B2 (en) 2012-10-20 2017-08-01 Masimo Corporation Magnetic-flap optical sensor
US9560996B2 (en) 2012-10-30 2017-02-07 Masimo Corporation Universal medical system
US9787568B2 (en) 2012-11-05 2017-10-10 Cercacor Laboratories, Inc. Physiological test credit method
US9750461B1 (en) 2013-01-02 2017-09-05 Masimo Corporation Acoustic respiratory monitoring sensor with probe-off detection
US9724025B1 (en) 2013-01-16 2017-08-08 Masimo Corporation Active-pulse blood analysis system
US9750442B2 (en) 2013-03-09 2017-09-05 Masimo Corporation Physiological status monitor
US10441181B1 (en) 2013-03-13 2019-10-15 Masimo Corporation Acoustic pulse and respiration monitoring system
WO2014164139A1 (en) 2013-03-13 2014-10-09 Masimo Corporation Systems and methods for monitoring a patient health network
US9986952B2 (en) 2013-03-14 2018-06-05 Masimo Corporation Heart sound simulator
US9936917B2 (en) 2013-03-14 2018-04-10 Masimo Laboratories, Inc. Patient monitor placement indicator
WO2014158820A1 (en) 2013-03-14 2014-10-02 Cercacor Laboratories, Inc. Patient monitor as a minimally invasive glucometer
WO2014168734A1 (en) 2013-03-15 2014-10-16 Cedars-Sinai Medical Center Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof
US10456038B2 (en) 2013-03-15 2019-10-29 Cercacor Laboratories, Inc. Cloud-based physiological monitoring system
US10004434B1 (en) 2013-03-15 2018-06-26 Georgetown University Microfluidic systems for electrochemical transdermal analyte sensing using a capillary-located electrode
RU2539817C1 (en) * 2013-07-16 2015-01-27 Федеральное государственное бюджетное учреждение "Федеральный Центр сердца, крови и Эндокринологии имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Apparatus for fluorescent spectroscopy of biological tissue
US9891079B2 (en) 2013-07-17 2018-02-13 Masimo Corporation Pulser with double-bearing position encoder for non-invasive physiological monitoring
US10555678B2 (en) 2013-08-05 2020-02-11 Masimo Corporation Blood pressure monitor with valve-chamber assembly
WO2015038683A2 (en) 2013-09-12 2015-03-19 Cercacor Laboratories, Inc. Medical device management system
US11147518B1 (en) 2013-10-07 2021-10-19 Masimo Corporation Regional oximetry signal processor
JP6484230B2 (en) 2013-10-07 2019-03-13 マシモ・コーポレイション Local oximetry sensor
US10828007B1 (en) 2013-10-11 2020-11-10 Masimo Corporation Acoustic sensor with attachment portion
US10832818B2 (en) 2013-10-11 2020-11-10 Masimo Corporation Alarm notification system
WO2015073871A2 (en) * 2013-11-14 2015-05-21 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
JP2017500550A (en) 2013-11-20 2017-01-05 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ System and method for hyperspectral analysis of cardiac tissue
US10279247B2 (en) 2013-12-13 2019-05-07 Masimo Corporation Avatar-incentive healthcare therapy
US10086138B1 (en) 2014-01-28 2018-10-02 Masimo Corporation Autonomous drug delivery system
US11259745B2 (en) 2014-01-28 2022-03-01 Masimo Corporation Autonomous drug delivery system
US10532174B2 (en) 2014-02-21 2020-01-14 Masimo Corporation Assistive capnography device
RU2551634C1 (en) * 2014-04-28 2015-05-27 Закрытое акционерное общество "Полупроводниковые приборы" Device for fluorescent diagnostics of malignant neoplasms
US9924897B1 (en) 2014-06-12 2018-03-27 Masimo Corporation Heated reprocessing of physiological sensors
US10123729B2 (en) 2014-06-13 2018-11-13 Nanthealth, Inc. Alarm fatigue management systems and methods
US10231670B2 (en) 2014-06-19 2019-03-19 Masimo Corporation Proximity sensor in pulse oximeter
WO2016011534A1 (en) 2014-07-24 2016-01-28 University Health Network Collection and analysis of data for diagnostic purposes
US10111591B2 (en) 2014-08-26 2018-10-30 Nanthealth, Inc. Real-time monitoring systems and methods in a healthcare environment
WO2016036985A1 (en) 2014-09-04 2016-03-10 Masimo Corportion Total hemoglobin index system
US10383520B2 (en) 2014-09-18 2019-08-20 Masimo Semiconductor, Inc. Enhanced visible near-infrared photodiode and non-invasive physiological sensor
WO2016057553A1 (en) 2014-10-07 2016-04-14 Masimo Corporation Modular physiological sensors
EP3215001A4 (en) 2014-11-03 2018-04-04 Luxcath, LLC Systems and methods for assessment of contact quality
CN113143440A (en) 2014-11-03 2021-07-23 乔治华盛顿大学 Systems and methods for injury assessment
CN104483299A (en) * 2014-12-10 2015-04-01 安徽理工大学 Method for identifying water hazard water source of mining area
AU2016209104B2 (en) 2015-01-23 2020-04-30 Masimo Sweden Ab Nasal/oral cannula system and manufacturing
USD755392S1 (en) 2015-02-06 2016-05-03 Masimo Corporation Pulse oximetry sensor
US10568553B2 (en) 2015-02-06 2020-02-25 Masimo Corporation Soft boot pulse oximetry sensor
US10205291B2 (en) 2015-02-06 2019-02-12 Masimo Corporation Pogo pin connector
KR20230170116A (en) 2015-02-06 2023-12-18 마시모 코오퍼레이션 Fold flex circuit for optical probes
US11202606B2 (en) 2015-04-17 2021-12-21 Koninklijke Philips N.V. Detection of anisotropic biological tissue
US10524738B2 (en) 2015-05-04 2020-01-07 Cercacor Laboratories, Inc. Noninvasive sensor system with visual infographic display
US11653862B2 (en) 2015-05-22 2023-05-23 Cercacor Laboratories, Inc. Non-invasive optical physiological differential pathlength sensor
US10448871B2 (en) 2015-07-02 2019-10-22 Masimo Corporation Advanced pulse oximetry sensor
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US11656180B2 (en) 2015-08-03 2023-05-23 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
US11219390B2 (en) 2015-08-03 2022-01-11 Georgetown University Apparatus and method for delivery of antimicrobial during a transdermal sampling and delivery process
US20170038301A1 (en) * 2015-08-03 2017-02-09 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
CN108135503A (en) 2015-08-11 2018-06-08 迈心诺公司 The medical monitoring analysis and playback of label including the light in response to being decayed by bodily tissue
EP3344123B1 (en) 2015-08-31 2022-10-26 Masimo Corporation Wireless patient monitoring methods
US11504066B1 (en) 2015-09-04 2022-11-22 Cercacor Laboratories, Inc. Low-noise sensor system
US11679579B2 (en) 2015-12-17 2023-06-20 Masimo Corporation Varnish-coated release liner
US10799129B2 (en) * 2016-01-07 2020-10-13 Panasonic Intellectual Property Management Co., Ltd. Biological information measuring device including light source, light detector, and control circuit
US10537285B2 (en) 2016-03-04 2020-01-21 Masimo Corporation Nose sensor
US10993662B2 (en) 2016-03-04 2021-05-04 Masimo Corporation Nose sensor
JP7266519B2 (en) 2016-04-01 2023-04-28 ブラック ライト サージカル， インコーポレイテッド Systems, devices and methods for time-resolved fluorescence spectroscopy
US11191484B2 (en) 2016-04-29 2021-12-07 Masimo Corporation Optical sensor tape
WO2018009612A1 (en) 2016-07-06 2018-01-11 Patient Doctor Technologies, Inc. Secure and zero knowledge data sharing for cloud applications
US10617302B2 (en) 2016-07-07 2020-04-14 Masimo Corporation Wearable pulse oximeter and respiration monitor
JP7197473B2 (en) 2016-10-13 2022-12-27 マシモ・コーポレイション System and method for patient fall detection
US11504058B1 (en) 2016-12-02 2022-11-22 Masimo Corporation Multi-site noninvasive measurement of a physiological parameter
US10750984B2 (en) 2016-12-22 2020-08-25 Cercacor Laboratories, Inc. Methods and devices for detecting intensity of light with translucent detector
US10721785B2 (en) 2017-01-18 2020-07-21 Masimo Corporation Patient-worn wireless physiological sensor with pairing functionality
WO2018156809A1 (en) 2017-02-24 2018-08-30 Masimo Corporation Augmented reality system for displaying patient data
WO2018156648A1 (en) 2017-02-24 2018-08-30 Masimo Corporation Managing dynamic licenses for physiological parameters in a patient monitoring environment
US10388120B2 (en) 2017-02-24 2019-08-20 Masimo Corporation Localized projection of audible noises in medical settings
US10327713B2 (en) 2017-02-24 2019-06-25 Masimo Corporation Modular multi-parameter patient monitoring device
US11417426B2 (en) 2017-02-24 2022-08-16 Masimo Corporation System for displaying medical monitoring data
US11086609B2 (en) 2017-02-24 2021-08-10 Masimo Corporation Medical monitoring hub
EP3592231A1 (en) 2017-03-10 2020-01-15 Masimo Corporation Pneumonia screener
WO2018194992A1 (en) 2017-04-18 2018-10-25 Masimo Corporation Nose sensor
US10918281B2 (en) 2017-04-26 2021-02-16 Masimo Corporation Medical monitoring device having multiple configurations
USD835285S1 (en) 2017-04-28 2018-12-04 Masimo Corporation Medical monitoring device
USD835282S1 (en) 2017-04-28 2018-12-04 Masimo Corporation Medical monitoring device
CN110891472B (en) 2017-04-28 2023-04-04 迈心诺公司 Spot check measuring system
USD835284S1 (en) 2017-04-28 2018-12-04 Masimo Corporation Medical monitoring device
USD835283S1 (en) 2017-04-28 2018-12-04 Masimo Corporation Medical monitoring device
WO2018208616A1 (en) 2017-05-08 2018-11-15 Masimo Corporation System for pairing a medical system to a network controller by use of a dongle
US11026604B2 (en) 2017-07-13 2021-06-08 Cercacor Laboratories, Inc. Medical monitoring device for harmonizing physiological measurements
USD906970S1 (en) 2017-08-15 2021-01-05 Masimo Corporation Connector
JP7278260B2 (en) 2017-08-15 2023-05-19 マシモ・コーポレイション Waterproof connectors for non-invasive patient monitoring
USD890708S1 (en) 2017-08-15 2020-07-21 Masimo Corporation Connector
EP3675713A1 (en) 2017-10-19 2020-07-08 Masimo Corporation Display arrangement for medical monitoring system
JP2019078715A (en) * 2017-10-27 2019-05-23 セイコーエプソン株式会社 Spectrometry device and method for spectrometry
USD925597S1 (en) 2017-10-31 2021-07-20 Masimo Corporation Display screen or portion thereof with graphical user interface
US10987066B2 (en) 2017-10-31 2021-04-27 Masimo Corporation System for displaying oxygen state indications
US11766198B2 (en) 2018-02-02 2023-09-26 Cercacor Laboratories, Inc. Limb-worn patient monitoring device
US10952616B2 (en) 2018-03-30 2021-03-23 Canon U.S.A., Inc. Fluorescence imaging apparatus
EP3782165A1 (en) 2018-04-19 2021-02-24 Masimo Corporation Mobile patient alarm display
US11883129B2 (en) 2018-04-24 2024-01-30 Cercacor Laboratories, Inc. Easy insert finger sensor for transmission based spectroscopy sensor
EP3801207A1 (en) 2018-06-06 2021-04-14 Masimo Corporation Opioid overdose monitoring
US10779098B2 (en) 2018-07-10 2020-09-15 Masimo Corporation Patient monitor alarm speaker analyzer
US11872156B2 (en) 2018-08-22 2024-01-16 Masimo Corporation Core body temperature measurement
US10743749B2 (en) 2018-09-14 2020-08-18 Canon U.S.A., Inc. System and method for detecting optical probe connection
USD998631S1 (en) 2018-10-11 2023-09-12 Masimo Corporation Display screen or portion thereof with a graphical user interface
USD999246S1 (en) 2018-10-11 2023-09-19 Masimo Corporation Display screen or portion thereof with a graphical user interface
US11406286B2 (en) 2018-10-11 2022-08-09 Masimo Corporation Patient monitoring device with improved user interface
US11389093B2 (en) 2018-10-11 2022-07-19 Masimo Corporation Low noise oximetry cable
US11445948B2 (en) 2018-10-11 2022-09-20 Masimo Corporation Patient connector assembly with vertical detents
USD917550S1 (en) 2018-10-11 2021-04-27 Masimo Corporation Display screen or portion thereof with a graphical user interface
USD998630S1 (en) 2018-10-11 2023-09-12 Masimo Corporation Display screen or portion thereof with a graphical user interface
USD916135S1 (en) 2018-10-11 2021-04-13 Masimo Corporation Display screen or portion thereof with a graphical user interface
USD917564S1 (en) 2018-10-11 2021-04-27 Masimo Corporation Display screen or portion thereof with graphical user interface
WO2020077149A1 (en) 2018-10-12 2020-04-16 Masimo Corporation System for transmission of sensor data using dual communication protocol
US11464410B2 (en) 2018-10-12 2022-10-11 Masimo Corporation Medical systems and methods
USD897098S1 (en) 2018-10-12 2020-09-29 Masimo Corporation Card holder set
CN109270044A (en) * 2018-11-28 2019-01-25 安徽理工大学 A kind of laser induced fluorescence vegetable oil doping strong tea water identification method
US11684296B2 (en) 2018-12-21 2023-06-27 Cercacor Laboratories, Inc. Noninvasive physiological sensor
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
WO2020214826A1 (en) 2019-04-17 2020-10-22 Masimo Corporation Patient monitoring systems, devices, and methods
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
USD919100S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Holder for a patient monitor
USD917704S1 (en) 2019-08-16 2021-04-27 Masimo Corporation Patient monitor
USD919094S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Blood pressure device
USD985498S1 (en) 2019-08-16 2023-05-09 Masimo Corporation Connector
USD921202S1 (en) 2019-08-16 2021-06-01 Masimo Corporation Holder for a blood pressure device
US11832940B2 (en) 2019-08-27 2023-12-05 Cercacor Laboratories, Inc. Non-invasive medical monitoring device for blood analyte measurements
EP4046164A1 (en) 2019-10-18 2022-08-24 Masimo Corporation Display layout and interactive objects for patient monitoring
USD927699S1 (en) 2019-10-18 2021-08-10 Masimo Corporation Electrode pad
EP4104037A1 (en) 2020-02-13 2022-12-21 Masimo Corporation System and method for monitoring clinical activities
US11879960B2 (en) 2020-02-13 2024-01-23 Masimo Corporation System and method for monitoring clinical activities
WO2021189002A1 (en) 2020-03-20 2021-09-23 Masimo Corporation Wearable device for noninvasive body temperature measurement
USD933232S1 (en) 2020-05-11 2021-10-12 Masimo Corporation Blood pressure monitor
USD979516S1 (en) 2020-05-11 2023-02-28 Masimo Corporation Connector
USD974193S1 (en) 2020-07-27 2023-01-03 Masimo Corporation Wearable temperature measurement device
USD980091S1 (en) 2020-07-27 2023-03-07 Masimo Corporation Wearable temperature measurement device
US10952655B1 (en) * 2020-09-21 2021-03-23 The Florida International University Board Of Trustees Retinal blood vessel oximetry using retinal auofluorescence
USD946596S1 (en) 2020-09-30 2022-03-22 Masimo Corporation Display screen or portion thereof with graphical user interface
USD946598S1 (en) 2020-09-30 2022-03-22 Masimo Corporation Display screen or portion thereof with graphical user interface
USD946597S1 (en) 2020-09-30 2022-03-22 Masimo Corporation Display screen or portion thereof with graphical user interface
USD997365S1 (en) 2021-06-24 2023-08-29 Masimo Corporation Physiological nose sensor
USD1000975S1 (en) 2021-09-22 2023-10-10 Masimo Corporation Wearable temperature measurement device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989012223A1 (en) * 1988-06-08 1989-12-14 Barbour Randall L A method of imaging a random medium
US5122974A (en) * 1989-02-06 1992-06-16 Nim, Inc. Phase modulated spectrophotometry
EP0703445A2 (en) * 1994-09-22 1996-03-27 Hamamatsu Photonics K.K. Method and apparatus for measuring concentration of absorptive constituent in scattering medium
WO1997008538A1 (en) * 1995-08-24 1997-03-06 Purdue Research Foundation Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175632D1 (en) * 1980-08-21 1987-01-08 Oriel Scient Ltd Analytical optical instruments
US4569354A (en) * 1982-03-22 1986-02-11 Boston University Method and apparatus for measuring natural retinal fluorescence
JPS60209146A (en) * 1984-03-31 1985-10-21 Olympus Optical Co Ltd Fluorescence spectrochemical analysis device
SE455646B (en) * 1984-10-22 1988-07-25 Radians Innova Ab FLUORESCENT DEVICE
DE3535652A1 (en) * 1984-11-01 1986-04-30 Jenoptik Jena Gmbh, Ddr 6900 Jena ARRANGEMENT FOR OPTICAL RADIATION IN PHOTOMETRIC ANALYZER MEASURING DEVICES
US4641650A (en) * 1985-03-11 1987-02-10 Mcm Laboratories, Inc. Probe-and-fire lasers
CN85100424B (en) * 1985-04-01 1986-10-29 上海医疗器械研究所 Inherent fluorescence diagnostic instrument for malignant tumor
US4945245A (en) * 1986-01-14 1990-07-31 Levin Herman W Evanescent wave background fluorescence/absorbance detection
US4996421A (en) * 1988-10-31 1991-02-26 Amoco Corporation Method an system of geophysical exploration
US5187672A (en) * 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
DE68925586T2 (en) * 1988-12-21 1996-10-24 Massachusetts Inst Technology METHOD FOR LASER-INDUCED FLUORESCENCE OF TISSUE
CA2042075C (en) * 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
US5635402A (en) * 1992-03-05 1997-06-03 Alfano; Robert R. Technique for determining whether a cell is malignant as opposed to non-malignant using extrinsic fluorescence spectroscopy
US5452723A (en) * 1992-07-24 1995-09-26 Massachusetts Institute Of Technology Calibrated spectrographic imaging
US5341805A (en) * 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
US5349954A (en) * 1993-07-23 1994-09-27 General Electric Company Tumor tissue characterization apparatus and method
US5456252A (en) * 1993-09-30 1995-10-10 Cedars-Sinai Medical Center Induced fluorescence spectroscopy blood perfusion and pH monitor and method
US5515864A (en) * 1994-04-21 1996-05-14 Zuckerman; Ralph Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime
US5760406A (en) * 1996-06-03 1998-06-02 Powers; Linda Method and apparatus for sensing the presence of microbes
US6124597A (en) 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy
US6219575B1 (en) * 1998-10-23 2001-04-17 Babak Nemati Method and apparatus to enhance optical transparency of biological tissues

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989012223A1 (en) * 1988-06-08 1989-12-14 Barbour Randall L A method of imaging a random medium
US5122974A (en) * 1989-02-06 1992-06-16 Nim, Inc. Phase modulated spectrophotometry
EP0703445A2 (en) * 1994-09-22 1996-03-27 Hamamatsu Photonics K.K. Method and apparatus for measuring concentration of absorptive constituent in scattering medium
WO1997008538A1 (en) * 1995-08-24 1997-03-06 Purdue Research Foundation Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media

Also Published As

Publication number Publication date
AU752061B2 (en) 2002-09-05
US6124597A (en) 2000-09-26
WO1999002956A2 (en) 1999-01-21
AU7830698A (en) 1999-02-08
EP0995095B1 (en) 2005-04-06
DE69829664D1 (en) 2005-05-12
USRE39672E1 (en) 2007-06-05
EP1562038A2 (en) 2005-08-10
EP0995095A2 (en) 2000-04-26
JP2001509589A (en) 2001-07-24
US6697657B1 (en) 2004-02-24
EP1562038A3 (en) 2005-11-23

Similar Documents

Publication Publication Date Title
WO1999002956A3 (en) Method and devices for laser induced fluorescence attenuation spectroscopy (lifas)
CA2238958A1 (en) Method and apparatus for facilitating compatibility between pulse oximeters and sensor probes
ATE153135T1 (en) METHOD AND DEVICE FOR MONITORING GLUCOSE CONCENTRATION
AUPM533094A0 (en) Methods and apparatus for determining a first parameter(s) of an object
WO2000009004A3 (en) Optical device
CA2174719A1 (en) A robust accurate non-invasive analyte monitor
CA2080691A1 (en) Method and apparatus for measuring the concentration of absorbing substances
ATE235674T1 (en) METHOD AND DEVICE FOR RAMAN CORRELATION SPECTROSCOPY
ATE101270T1 (en) SPECTROSCOPIC METHOD AND DEVICE FOR MEASUREMENT OF SUGAR CONTENT.
AU2599697A (en) Instrument and method for non-invasive monitoring of human tissue analyte by measuring the body's infrared radiation
WO1995007452A3 (en) Coagulation monitor
WO2002074161A3 (en) Subcutaneous analyte sensor
DE69212333D1 (en) METHOD AND SYSTEM FOR CONTROLLING A MATERIAL REMOVAL PROCESS; WHEN ANALYZING SPECTRAL RADIATION
CA2007776A1 (en) Phase modulated spectrophotometry
ES2113098T3 (en) FLUCORESCENCE GLUCOSE TESTER AND PROCEDURE.
EP0200342A3 (en) Evaluation of surface and subsurface characteristics of a sample
DE59608744D1 (en) METHOD AND DEVICE FOR DETERMINING ELECTROMAGNETIC WAVES FROM A MELT
CA2092985A1 (en) Detection of bacteria in blood culture bottles by time-resolved light scattering and absorption measurement
DE59510774D1 (en) Device and method for measuring the degree of browning of a food
EP1055457A3 (en) Sample support for the infrared spectroscopy of sample fluids
CA2122782A1 (en) Apparatus for Measuring an Ambient Physical Parameter Applied to a Highly Birefringent Sensing Fiber and Method
CA2286065A1 (en) Elastic radiation scatter-detecting safety device, analyzer apparatus provided with safety device, and method for controlling a laser excitation source
DE59709746D1 (en) Method and device for recording spectral remissions
WO2003014714A8 (en) Apparatus and method for the non-invasive measurement of parameters relating to biological tissues by spectroscopy, in particular with infra-red light
CA2238518A1 (en) Glucose monitoring apparatus and method using laser-induced emission spectroscopy

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AU JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1998926475

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 78306/98

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 1998926475

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 78306/98

Country of ref document: AU

WWG Wipo information: grant in national office

Ref document number: 1998926475

Country of ref document: EP