WO1999003684A3 - The production of microstructures for use in assays - Google Patents

The production of microstructures for use in assays Download PDF

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Publication number
WO1999003684A3
WO1999003684A3 PCT/GB1998/002161 GB9802161W WO9903684A3 WO 1999003684 A3 WO1999003684 A3 WO 1999003684A3 GB 9802161 W GB9802161 W GB 9802161W WO 9903684 A3 WO9903684 A3 WO 9903684A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
microstructures
assays
applying
onto
Prior art date
Application number
PCT/GB1998/002161
Other languages
French (fr)
Other versions
WO1999003684A8 (en
WO1999003684A2 (en
Inventor
Bernadette Yon-Hin
James Mccann
Saji Eapen
Christopher Robin Lowe
Original Assignee
Cambridge Sensors Ltd
Yon Hin Bernadette
James Mccann
Saji Eapen
Christopher Robin Lowe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Sensors Ltd, Yon Hin Bernadette, James Mccann, Saji Eapen, Christopher Robin Lowe filed Critical Cambridge Sensors Ltd
Priority to AT98935168T priority Critical patent/ATE228939T1/en
Priority to DE69809913T priority patent/DE69809913T2/en
Priority to EP98935168A priority patent/EP0996547B1/en
Priority to CA002293597A priority patent/CA2293597A1/en
Priority to JP2000502944A priority patent/JP2001510276A/en
Priority to US09/445,650 priority patent/US6440645B1/en
Publication of WO1999003684A2 publication Critical patent/WO1999003684A2/en
Publication of WO1999003684A3 publication Critical patent/WO1999003684A3/en
Publication of WO1999003684A8 publication Critical patent/WO1999003684A8/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00119—Arrangement of basic structures like cavities or channels, e.g. suitable for microfluidic systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
    • B41M1/00—Inking and printing with a printer's forme
    • B41M1/12—Stencil printing; Silk-screen printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
    • B41M3/00—Printing processes to produce particular kinds of printed work, e.g. patterns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00831—Glass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00833—Plastic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00909—Separation using filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0323—Grooves
    • B81B2203/0338—Channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00—Manufacture or treatment of microstructural devices or systems
    • B81C2201/01—Manufacture or treatment of microstructural devices or systems in or on a substrate
    • B81C2201/0174—Manufacture or treatment of microstructural devices or systems in or on a substrate for making multi-layered devices, film deposition or growing
    • B81C2201/0183—Selective deposition
    • B81C2201/0184—Digital lithography, e.g. using an inkjet print-head

Abstract

A process for the production of a device having a surface microstructure of wells or channels, comprises one or more steps of screen-printing the microstructure as a curable material onto a plastics substrate, and curing the material. Such a device may also be obtained by applying onto a substrate a material that is polymerisable or depolymerisable by irradiation, applying a negative or positive photoresist respectively, irradiating the structure and removing the unpolymerised or depolymerised material.
PCT/GB1998/002161 1997-07-18 1998-07-20 The production of microstructures for use in assays WO1999003684A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT98935168T ATE228939T1 (en) 1997-07-18 1998-07-20 THE PRODUCTION OF MICROSTRUCTURES FOR USE IN TESTS
DE69809913T DE69809913T2 (en) 1997-07-18 1998-07-20 THE PRODUCTION OF MICROSTRUCTURES FOR USE IN TESTS
EP98935168A EP0996547B1 (en) 1997-07-18 1998-07-20 The production of microstructures for use in assays
CA002293597A CA2293597A1 (en) 1997-07-18 1998-07-20 The production of microstructures for use in assays
JP2000502944A JP2001510276A (en) 1997-07-18 1998-07-20 Fabrication of microstructures for use in assays
US09/445,650 US6440645B1 (en) 1997-07-18 1998-07-20 Production of microstructures for use in assays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715101.3 1997-07-18
GB9715101A GB9715101D0 (en) 1997-07-18 1997-07-18 The production of microstructures for analysis of fluids

Publications (3)

Publication Number Publication Date
WO1999003684A2 WO1999003684A2 (en) 1999-01-28
WO1999003684A3 true WO1999003684A3 (en) 1999-05-14
WO1999003684A8 WO1999003684A8 (en) 1999-06-17

Family

ID=10816024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1998/002161 WO1999003684A2 (en) 1997-07-18 1998-07-20 The production of microstructures for use in assays

Country Status (8)

Country Link
US (1) US6440645B1 (en)
EP (1) EP0996547B1 (en)
JP (1) JP2001510276A (en)
AT (1) ATE228939T1 (en)
CA (1) CA2293597A1 (en)
DE (1) DE69809913T2 (en)
GB (1) GB9715101D0 (en)
WO (1) WO1999003684A2 (en)

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CA2293597A1 (en) 1999-01-28
WO1999003684A8 (en) 1999-06-17
JP2001510276A (en) 2001-07-31
EP0996547A2 (en) 2000-05-03
ATE228939T1 (en) 2002-12-15
EP0996547B1 (en) 2002-12-04
WO1999003684A2 (en) 1999-01-28
US6440645B1 (en) 2002-08-27
DE69809913D1 (en) 2003-01-16
DE69809913T2 (en) 2003-07-10

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