WO1999013852B1 - Methods and compositions for whitening teeth - Google Patents

Methods and compositions for whitening teeth

Info

Publication number
WO1999013852B1
WO1999013852B1 PCT/US1998/018500 US9818500W WO9913852B1 WO 1999013852 B1 WO1999013852 B1 WO 1999013852B1 US 9818500 W US9818500 W US 9818500W WO 9913852 B1 WO9913852 B1 WO 9913852B1
Authority
WO
WIPO (PCT)
Prior art keywords
bioactive
biocompatible glass
particulate
whitening
teeth
Prior art date
Application number
PCT/US1998/018500
Other languages
French (fr)
Other versions
WO1999013852A1 (en
Inventor
Leonard J Litkowski
Gary D Hack
David C Greenspan
Original Assignee
Univ Maryland
Usbiomaterials Corp
Leonard J Litkowski
Gary D Hack
David C Greenspan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to HU0100323A priority Critical patent/HUP0100323A2/en
Priority to SK382-2000A priority patent/SK3822000A3/en
Priority to PL98342475A priority patent/PL194695B1/en
Priority to KR1020007002843A priority patent/KR100548110B1/en
Priority to DK98946860T priority patent/DK1011621T3/en
Priority to AT98946860T priority patent/ATE297185T1/en
Priority to EP98946860A priority patent/EP1011621B1/en
Priority to DE69830500T priority patent/DE69830500T2/en
Application filed by Univ Maryland, Usbiomaterials Corp, Leonard J Litkowski, Gary D Hack, David C Greenspan filed Critical Univ Maryland
Priority to JP2000511478A priority patent/JP2001516709A/en
Priority to AU93785/98A priority patent/AU741771B2/en
Priority to IL13504398A priority patent/IL135043A0/en
Priority to BR9812339-4A priority patent/BR9812339A/en
Priority to CA002304010A priority patent/CA2304010C/en
Publication of WO1999013852A1 publication Critical patent/WO1999013852A1/en
Publication of WO1999013852B1 publication Critical patent/WO1999013852B1/en
Priority to US09/527,721 priority patent/US6365132B1/en
Priority to HK00108236A priority patent/HK1028959A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C03C4/0021—Compositions for glass with special properties for biologically-compatible glass for dental use

Abstract

Methods for whitening teeth including contacting teeth with an effective amount of particulate bioactive glass are disclosed.

Claims

AMENDED CLAIMS[received by the International Bureau on 25 March 1999 (25.03.99); original claims 5-8 amended; remaining claims unchanged (2 pages)]
1. A method for whitening teeth comprising contacting teeth with an effective tooth-whitening amount of particulate bioactive and biocompatible glass comprising silicon oxide or hydroxide and optionally one or more elements selected from Na, K, Ca, Mg, B, Ti, Al, P, N or F.
2. A method according to claim 1 wherein the bioactive and biocompatible glass comprises at least Na, Ca and P.
3. A method according to claim 1 or 2 wherein the bioactive and biocompatible glass is administered together with a source of calcium and/or phosphate.
4. A method according to any one of claims 1 to 3 wherein the bioactive and biocompatible glass includes by weight percentage:
SiO2 40-60
CaO 10-30
Na2O 10-35
P205 2-8
CaF2 0-25
B203 0-10
K2O 0-8
MgO 0-5.
5. A method according to any one of claims 1 to 4, wherein said particulate bioactive and biocompatible glass includes particles less than about 90 μm.
6. A method according to any one of claims 1 to 5, wherein said particulate bioactive and biocompatible glass includes particles less than about 10 μm.
10
7. A method according to any one of claims 1 to 6, wherein said particulate bioactive and biocompatible glass includes particles less than about 5 μm.
8. A method according to any one of claims 1 to 7, wherein said particulate bioactive and biocompatible glass includes particles less than about 2 μm.
9. A method according to any one of claims 1 to 8, wherein said effective amount is about 0.02 to about 0.3 grams.
10. A method according to any one of claims 1 to 9, wherein the particulate glass is in a toothpaste or gum.
11. A method for whitening teeth comprising contacting teeth with an effective shade reducing amount of particulate bioactive and biocompatible glass as defined in any one of claims 1 to 8.
12. A tooth-whitening oral hygiene composition comprising an effective tooth-whitening amount of particulate bioactive and biocompatible glass as defined in any one of claims 1 to 8.
11
PCT/US1998/018500 1997-09-18 1998-09-18 Methods and compositions for whitening teeth WO1999013852A1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP2000511478A JP2001516709A (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
SK382-2000A SK3822000A3 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
AU93785/98A AU741771B2 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
DK98946860T DK1011621T3 (en) 1997-09-18 1998-09-18 Methods and preparations for whitening teeth
AT98946860T ATE297185T1 (en) 1997-09-18 1998-09-18 METHODS AND COMPOSITIONS FOR BLEACHING TEETH
EP98946860A EP1011621B1 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
DE69830500T DE69830500T2 (en) 1997-09-18 1998-09-18 METHOD AND COMPOSITIONS FOR BLEACHING TEETH
HU0100323A HUP0100323A2 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
PL98342475A PL194695B1 (en) 1997-09-18 1998-09-18 Method of and composition for whitening teeth
KR1020007002843A KR100548110B1 (en) 1997-09-18 1998-09-18 Methods and Compositions For Whitening Teeth
IL13504398A IL135043A0 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
BR9812339-4A BR9812339A (en) 1997-09-18 1998-09-18 Process for whitening teeth, and oral hygiene composition for tooth whitening
CA002304010A CA2304010C (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth
US09/527,721 US6365132B1 (en) 1997-09-18 2000-03-17 Methods and compositions for whitening teeth
HK00108236A HK1028959A1 (en) 1997-09-18 2000-12-20 Methods and compositions for whitening teeth.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5922297P 1997-09-18 1997-09-18
US60/059,222 1997-09-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/527,721 Continuation US6365132B1 (en) 1997-09-18 2000-03-17 Methods and compositions for whitening teeth

Publications (2)

Publication Number Publication Date
WO1999013852A1 WO1999013852A1 (en) 1999-03-25
WO1999013852B1 true WO1999013852B1 (en) 1999-06-03

Family

ID=22021584

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/018500 WO1999013852A1 (en) 1997-09-18 1998-09-18 Methods and compositions for whitening teeth

Country Status (28)

Country Link
US (1) US6365132B1 (en)
EP (1) EP1011621B1 (en)
JP (1) JP2001516709A (en)
KR (1) KR100548110B1 (en)
CN (1) CN1149066C (en)
AR (1) AR015451A1 (en)
AT (1) ATE297185T1 (en)
AU (1) AU741771B2 (en)
BG (1) BG65005B1 (en)
BR (1) BR9812339A (en)
CA (1) CA2304010C (en)
CO (1) CO4970703A1 (en)
DE (1) DE69830500T2 (en)
DK (1) DK1011621T3 (en)
ES (1) ES2242297T3 (en)
HK (1) HK1028959A1 (en)
HU (1) HUP0100323A2 (en)
ID (1) ID24592A (en)
IL (1) IL135043A0 (en)
IN (1) IN191261B (en)
PE (1) PE116899A1 (en)
PL (1) PL194695B1 (en)
PT (1) PT1011621E (en)
SK (1) SK3822000A3 (en)
TR (1) TR200000740T2 (en)
TW (1) TWI228995B (en)
WO (1) WO1999013852A1 (en)
ZA (1) ZA988573B (en)

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Also Published As

Publication number Publication date
DK1011621T3 (en) 2005-08-29
HUP0100323A2 (en) 2001-06-28
TR200000740T2 (en) 2000-11-21
ES2242297T3 (en) 2005-11-01
DE69830500D1 (en) 2005-07-14
JP2001516709A (en) 2001-10-02
DE69830500T2 (en) 2006-03-30
EP1011621A4 (en) 2000-12-27
EP1011621A1 (en) 2000-06-28
CA2304010C (en) 2009-09-29
EP1011621B1 (en) 2005-06-08
PE116899A1 (en) 1999-11-19
WO1999013852A1 (en) 1999-03-25
HK1028959A1 (en) 2001-03-16
BG104330A (en) 2000-12-29
ATE297185T1 (en) 2005-06-15
PT1011621E (en) 2005-10-31
AR015451A1 (en) 2001-05-02
KR100548110B1 (en) 2006-02-02
IN191261B (en) 2003-10-18
CN1149066C (en) 2004-05-12
PL342475A1 (en) 2001-06-04
TWI228995B (en) 2005-03-11
KR20010030615A (en) 2001-04-16
BG65005B1 (en) 2006-12-29
CN1290158A (en) 2001-04-04
US6365132B1 (en) 2002-04-02
IL135043A0 (en) 2001-07-24
CA2304010A1 (en) 1999-03-25
ID24592A (en) 2000-07-27
BR9812339A (en) 2000-09-19
AU9378598A (en) 1999-04-05
AU741771B2 (en) 2001-12-06
CO4970703A1 (en) 2000-11-07
SK3822000A3 (en) 2000-08-14
PL194695B1 (en) 2007-06-29
ZA988573B (en) 1999-03-31

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