WO1999029265A1 - Frosted haptic intraocular lens - Google Patents

Frosted haptic intraocular lens Download PDF

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Publication number
WO1999029265A1
WO1999029265A1 PCT/US1998/025718 US9825718W WO9929265A1 WO 1999029265 A1 WO1999029265 A1 WO 1999029265A1 US 9825718 W US9825718 W US 9825718W WO 9929265 A1 WO9929265 A1 WO 9929265A1
Authority
WO
WIPO (PCT)
Prior art keywords
haptic
lens according
frosted
portions
lens
Prior art date
Application number
PCT/US1998/025718
Other languages
French (fr)
Other versions
WO1999029265A8 (en
Inventor
Thomas J. Chambers
Original Assignee
Staar Surgical Company, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Staar Surgical Company, Inc. filed Critical Staar Surgical Company, Inc.
Priority to CA002313334A priority Critical patent/CA2313334A1/en
Priority to KR1020007006368A priority patent/KR100602461B1/en
Priority to AU18033/99A priority patent/AU759433B2/en
Priority to EP98962893A priority patent/EP1039850A4/en
Priority to JP2000523943A priority patent/JP2001525219A/en
Publication of WO1999029265A1 publication Critical patent/WO1999029265A1/en
Publication of WO1999029265A8 publication Critical patent/WO1999029265A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1683—Intraocular lenses having supporting structure for lens, e.g. haptics having filiform haptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1689—Intraocular lenses having supporting structure for lens, e.g. haptics having plate-haptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body

Definitions

  • the present invention is directed to an intraocular lens having frosted haptic portions.
  • the present invention is particularly suitable for one-piece plate-type
  • the other main type is a
  • intraocular lens having a pair of opposed haptics extending from the lens portion and molded together as a one-piece integral construction. Further, intraocular lenses can be differentiated by cataract lens replacement-
  • the haptic portions of both three (3) piece type IOLs and one-piece plate-type IOLs have substantially smooth surface textures due to the various methods
  • plate-type intraocular lenses are examples of manufacturing these types of lenses.
  • plate-type intraocular lenses are examples of manufacturing these types of lenses.
  • one-piece plate-type IOLs are made from virgin silicon or acrylic based materials that are optically clear and not colored before and after molding thereof. Any appreciable coloring (i.e. , clouding or browning) of this material is considered
  • An object of the present invention is to provide an improved deformable
  • a second object according to the present invention is to provide a deformable intraocular lens having one or more frosted and/or textured surface portions.
  • a third object according to the present invention is to provide a deformable
  • intraocular lens having haptic portions having one or more frosted and/or textured
  • a fourth object of the present invention is to provide a three (3) piece type intraocular lens having haptic portions with one or more textured surface portions.
  • a fifth object of the present invention is to provide a one-piece plate-type
  • intraocular lens having plate-type haptics with one or more frosted and/or textured
  • a sixth object of the present invention is to provide a deformable one-piece
  • plate-type deformable intraocular lens having plate-type haptics with frosted and/or
  • the present invention is directed to various types of deformable intraocular lenses having frosted and/or textured haptic portions. These surface finishes alter the
  • optical and physical characteristics e.g. , optical clarity, surface friction, surface
  • the haptic portions can be provided with a frosted finish that effects the transmission of light through the haptic portions, the haptic portions can be provided with a matte finish that scatters reflected light in
  • haptic portions can be provided with an etched finish that
  • the present invention encompasses all types of deformable intraocular lenses,
  • the deformable intraocular lenses include three
  • anterior chamber and/or posterior chamber type IOLs are types of anterior chamber and/or posterior chamber type IOLs. Further, the present invention
  • invention is directed to providing one-piece plate-type IOLs with colored haptic
  • portions Specifically , limited portions or the entire haptics portions of one-piece plate-
  • the deformable IOLs according to the present invention are provided with
  • haptic portions that include frosted and/or textured surfaces. Specifically, portions of
  • the surfaces or the entire surfaces of the haptic portions are frosted and/or textured.
  • the frosted surface portions can be continuous or non-continuous with other portions.
  • frosted surface portions for example, can include stripes, checkerboard, dots, circles, triangles, squares, pentagons, octagons, lattice or virtually any other type of design including potentially art work.
  • the frosting can be provided
  • the frosted and/or textured surface portions can be applied to the deformable
  • IOLs by various methods including molding or surface texturing. Specifically, surfaces
  • the mold can be frosted or textured (e.g. , sandblasting, electrode discharge machining (EDM), shot peening, laser etching chemical etching, sputtering, vapor
  • deformable IOLs can be frosted or textured by, for example, sandblasting or shot
  • peening haptic portion of the lens chemically etching frosted surface portions
  • the frosted and/or textured surface portions of the haptic portions increase
  • IOL inner structure of the eye.
  • haptics portions are preferably frosted and/or textured to increase the total surface area that is frosted, and thus increase the amount of frictional resistance to movement of the
  • the frosted and/or textured surfaces of the haptic portions will also decrease the
  • a portion of one or both haptic portions can be intentionally colored.
  • the coloration can be
  • the same surface portions can be both frosted and colored, or different
  • portions can be frosted and not colored while other portions are not frosted, but
  • the coloration can be utilized to reduce the transmittance of light through the
  • haptic portions for marking the lens (e.g. , trademark logos, lens orientation markings,
  • Figure 1 is a perspective view of an intraocular lens according to the present invention having frosted surfaces on the haptic portions.
  • Figure 2 is a top planar view of the intraocular lens shown in Figure 1.
  • Figure 3 is a rear view of the deformable intraocular lens show in Figure 1.
  • Figure 4 is a side elevational view of the deformable intraocular lens show in
  • Figure 5 is a partial broken-away transverse cross-sectional view of a haptic portion, as indicated in Figure 2.
  • Figure 6 is a top planar view of another embodiment of the deformable intraocular
  • Figure 7 is a partial broken-away side cross-sectional view of the haptic portion, as indicated in Figure 6.
  • Figure 8 is a front elevational view of an intraocular lens according to the present invention having both frosted and colored haptic portions.
  • Figure 9 is a partial broken-away side cross-sectional view of the haptic portion
  • Figure 10 is a perspective view of an actual one-piece plate-type deformable
  • Figure 11 is a detailed partial broken-away perspective view of the IOL shown in Figure 10.
  • Deformable intraocular lens - means an intraocular lens made of an elastic
  • typical deformable intraocular lens are made of silicone elastomer, acrylic elastomer, or collagen-based
  • polymer e.g., COLLAMER made by STAAR Surgical of Monrovia, California.
  • Flaws - mean unintentional, unexpected, and unwanted interruptions
  • Frosted Surface - means a roughened surface that reduces the transmission of light therethrough.
  • Lay - means the direction of the predominant surface pattern, ordinarily determined by the production method used.
  • Matte Surface - means a dull surface that scatters reflected light in all directions.
  • Measured profile - means a representation of the profiled obtained by instrumental or other means.
  • Measured surface - means a representation of the surface obtained by instrumental
  • Nominal profile - means a profile of the nominal surface; it is the intended profile
  • Nominal surface - means the intended surface contour (exclusive of any intended
  • Peak - means the point of maximum height on that portion of a profile that lies
  • Roughness - means the finer irregularities of surface texture, usually including those irregularities which result from the inherent action of the production process. These are considered to include traverse feed marks and other irregularities within the limits of the roughness sampling length.
  • Roughness sampling length - means the sampling length within which the
  • Roughness spacing - means the average spacing between adjacent peaks of the measured profile within the roughness sampling length.
  • Sampling length - means the nominal spacing within which a surface characteristic is determined. Spacing - means the distance between specified points on the profile measured
  • Surface texture - means the repetitive of random deviations from the nominal surface which form the three-dimensional topography of the surface.
  • Valley - means the point of maximum depth on that portion of a profile that lies
  • Waviness means the more widely spaced component of surface texture. Unless otherwise noted, waviness is to include all irregularities whose spacing is greater than the
  • Waviness may
  • Waviness spacing - means the average spacing between adjacent peaks of the
  • a plate-type deformable intraocular lens 10 according to the present invention is a plate-type deformable intraocular lens 10 according to the present invention.
  • the deformable intraocular lens 10 comprises a lens portion 12 and
  • haptic portion 14 including haptic portions 14a and 14b.
  • the haptic portions 14a and 14b are haptic portions 14a and 14b.
  • frosted surface portions 16a and 16b are provided with frosted surface portions 16a and 16b, respectively. As shown in Figs.
  • both sides of the haptic portions 14a and 14b are provided with frosted surface
  • the intraocular lens 20 includes a lens portion 22 and haptic
  • haptic portion 24 including haptic portions 24a and 24b.
  • the haptic portions 24a and 24b are
  • the colored portions 24a and 24b can be made by coloring, dying, painting,
  • the coloring material can be added to the
  • lens material e.g., before or during formation of the lens
  • lens material e.g., before or during formation of the lens
  • the coloring material can be of a type to leave the haptic material transparent with coloring (e.g., tinting), or can be of a type to make the haptic material opaque (e.g., color pigment or dye).
  • the frosted and/or textured surface portions of the haptics are provided by forming or making portions of the haptic having a particular surface roughness.
  • the roughness of a surface is based on the dimensional aspects of gaps and protrusions in the surface of the haptics.
  • the surface roughness can be further
  • width of the gaps of from 8-128 microns a mean value of thickness of the protrusions of from 8-128 microns, a mean value of the depth of the gaps of 8-128 microns, and a mean value of spacing between gaps in a range of 8-128 microns.
  • the mean surface roughness is the mean surface roughness
  • the mean value of width of the gaps is from 16-64 microns
  • the mean value of the thickness of the protrusions is from 16-64 microns
  • the mean value of the depth of the gaps is 16-64 microns
  • the mean value of the spacing between gaps is 16-64 microns.
  • preferred surface roughness is characterized by a mean value of width of the gaps of 32
  • deformable IOL shown in Figure 10 was made by injection molding standard silicon polymer material in a metal mold, followed by tumble polishing.
  • the metal mold was prepared by electro discharge machining (EDM) to cut the
  • the lens was then molded by conventional molding techniques for manufacturing the silicon deformable intraocular lens.

Abstract

The present invention is a deformable intraocular lens (10) having frosted, and/or colored haptic portions (16a, 16b). The frosted haptic portions increase the frictional resistance to movement or rotation within the inner structure of the eye once implanted.

Description

FROSTED HAPTIC INTRA OCULAR LENS
Field of the Invention
The present invention is directed to an intraocular lens having frosted haptic portions. The present invention is particularly suitable for one-piece plate-type
intraocular lenses.
Background of the Invention
The concept of a deformable intraocular lens (IOL) was invented and developed in the early 1980' s by Dr. Mazzacco who became a founder of Staar Surgical Company of Monrovia, California. Staar Surgical Company has been an innovator of deformable
IOLs, and is a leading manufacturer and marketer of deformable IOLs in the United
States and throughout the world.
There exists two main types of deformable intraocular lenses having different
types of configurations for attaching the lens in the eye. Specifically, there exists a
three (3) piece lens, including a lens portion and two separate loop-type haptics each
having one end embedded in the lens portion of the lens. The other main type is a
plate-type intraocular lens having a pair of opposed haptics extending from the lens portion and molded together as a one-piece integral construction. Further, intraocular lenses can be differentiated by cataract lens replacement-
type in which the natural crystalline lens is removed and replaced by an intraocular
lens, and a refractive type of intraocular lens to be added in front of the natural
crystalline lens without removal thereof.
Currently, the haptic portions of both three (3) piece type IOLs and one-piece plate-type IOLs have substantially smooth surface textures due to the various methods
of manufacturing these types of lenses. In particular, plate-type intraocular lenses are
tumble polished so that the entire surface is very smooth and highly transparent.
Further, one-piece plate-type IOLs currently being marketed and sold are
uniformly optically clear and have no appreciable coloration. Specifically, currently
marketed one-piece plate-type IOLs are made from virgin silicon or acrylic based materials that are optically clear and not colored before and after molding thereof. Any appreciable coloring (i.e. , clouding or browning) of this material is considered
defective, and such lenses are typically discarded under quality control.
Summary of the Invention
An object of the present invention is to provide an improved deformable
intraocular lens. A second object according to the present invention is to provide a deformable intraocular lens having one or more frosted and/or textured surface portions.
A third object according to the present invention is to provide a deformable
intraocular lens having haptic portions having one or more frosted and/or textured
surface portions.
A fourth object of the present invention is to provide a three (3) piece type intraocular lens having haptic portions with one or more textured surface portions.
A fifth object of the present invention is to provide a one-piece plate-type
intraocular lens having plate-type haptics with one or more frosted and/or textured
surface portions.
A sixth object of the present invention is to provide a deformable one-piece
plate-type deformable intraocular lens having plate-type haptics with frosted and/or
textured surface end portions.
The present invention is directed to various types of deformable intraocular lenses having frosted and/or textured haptic portions. These surface finishes alter the
optical and physical characteristics (e.g. , optical clarity, surface friction, surface
adhesion, surface tension, porosity, surface hardness, etc.) of the surfaces of the haptic portions of the deformable IOLs. For example, the haptic portions can be provided with a frosted finish that effects the transmission of light through the haptic portions, the haptic portions can be provided with a matte finish that scatters reflected light in
all directions; and/or the haptic portions can be provided with an etched finish that
provides a roughened surface texture finish to increase frictional contact with the inner
eye tissue.
The present invention encompasses all types of deformable intraocular lenses,
however, one-piece plate-type deformable intraocular lenses are of particular interest with respect to the present invention. The deformable intraocular lenses include three
(3) piece type IOLs, one-piece plate-type intraocular IOLs, deformable refractive correction IOLs (e.g. , Staar Surgical Company's Intraocular Contact Lens) and other
types of anterior chamber and/or posterior chamber type IOLs. Further, the present
invention is directed to providing one-piece plate-type IOLs with colored haptic
portions . Specifically , limited portions or the entire haptics portions of one-piece plate-
type IOLs are colored.
The deformable IOLs according to the present invention are provided with
haptic portions that include frosted and/or textured surfaces. Specifically, portions of
the surfaces or the entire surfaces of the haptic portions are frosted and/or textured.
The frosted surface portions can be continuous or non-continuous with other portions.
Various designs of the frosted surface portions, for example, can include stripes, checkerboard, dots, circles, triangles, squares, pentagons, octagons, lattice or virtually any other type of design including potentially art work. The frosting can be provided
on the front, back and/or edge surfaces.
The frosted and/or textured surface portions can be applied to the deformable
IOLs by various methods including molding or surface texturing. Specifically, surfaces
of the mold can be frosted or textured (e.g. , sandblasting, electrode discharge machining (EDM), shot peening, laser etching chemical etching, sputtering, vapor
depositing, etc.). Alternatively or in addition, the surfaces of the haptic portions of the
deformable IOLs can be frosted or textured by, for example, sandblasting or shot
peening haptic portion of the lens, chemically etching frosted surface portions,
irradiating portions to become frosted or non-frosted, chemically etching portions to
become frosted or non-frosted, masking techniques, irradiating, surface modifying or
other various techniques to make portions of the haptic transparent, lightly frosted or textured, medium frosted or textured, highly frosted or textured, or frosted or textured to any degree therebetween.
The frosted and/or textured surface portions of the haptic portions increase
friction in the interface between tissue and haptic portion to increase the extent of
anchoring the IOL within the eye. It is highly desirable to anchor and minimize
movement of the IOL and prevent any relevant movement (e.g. , rotation) between the
IOL and inner structure of the eye. Typically, there only exists the possibility of some movement, post operatively prior to healing of the tissue in the eye (i.e. , up to several
weeks). It is during this time period that it would be highly desirable to prevent any
relative movement and/or rotation of the implanted IOL within the eye structure.
Based on mechanics, it is highly desirable that tip portions of the haptic portions
are frosted and/or textured to provide the greatest moment arm for frictional forces
applied from the eye tissue on the haptic portions to prevent relative movement and/or rotation of the IOL within the eye structure. Further, both sides and the edges of the
haptics portions are preferably frosted and/or textured to increase the total surface area that is frosted, and thus increase the amount of frictional resistance to movement of the
IOL within the eye structure.
The frosted and/or textured surfaces of the haptic portions will also decrease the
amount of light being transmitted through the haptic portions.
In the context of a one-piece plate- type IOL according to the present invention,
a portion of one or both haptic portions can be intentionally colored. The coloration can
render the haptics opaque, or partially transmissive (i.e. , translucent). The coloration
can be used independent of any surface frosting, or in combination therewith. For
example, the same surface portions can be both frosted and colored, or different
portions can be frosted and not colored while other portions are not frosted, but
colored. The coloration can be utilized to reduce the transmittance of light through the
haptic portions, for marking the lens (e.g. , trademark logos, lens orientation markings,
art work, bar codes, etc.).
Brief Description of the Drawings
Figure 1 is a perspective view of an intraocular lens according to the present invention having frosted surfaces on the haptic portions.
Figure 2 is a top planar view of the intraocular lens shown in Figure 1.
Figure 3 is a rear view of the deformable intraocular lens show in Figure 1.
Figure 4 is a side elevational view of the deformable intraocular lens show in
Figure 1.
Figure 5 is a partial broken-away transverse cross-sectional view of a haptic portion, as indicated in Figure 2.
Figure 6 is a top planar view of another embodiment of the deformable intraocular
lens according to the present invention having colored zones on the haptic portions. Figure 7 is a partial broken-away side cross-sectional view of the haptic portion, as indicated in Figure 6.
Figure 8 is a front elevational view of an intraocular lens according to the present invention having both frosted and colored haptic portions.
Figure 9 is a partial broken-away side cross-sectional view of the haptic portion,
as indicated in Figure 8.
Figure 10 is a perspective view of an actual one-piece plate-type deformable
intraocular lens according to the present invention by electron micrograph showing details
of the frosted haptic portions.
Figure 11 is a detailed partial broken-away perspective view of the IOL shown in Figure 10.
Detailed Description of Preferred Embodiments
Definitions
Deformable intraocular lens - means an intraocular lens made of an elastic
material capable of being folded, rolled or compressed to fit through a relatively small
incision (e.g., 2.5 to 3.0 mm) made in the eye. For example, typical deformable intraocular lens are made of silicone elastomer, acrylic elastomer, or collagen-based
polymer (e.g., COLLAMER made by STAAR Surgical of Monrovia, California).
Flaws - mean unintentional, unexpected, and unwanted interruptions
Frosted Surface - means a roughened surface that reduces the transmission of light therethrough.
Lay - means the direction of the predominant surface pattern, ordinarily determined by the production method used.
Matte Surface - means a dull surface that scatters reflected light in all directions.
Measured profile - means a representation of the profiled obtained by instrumental or other means.
Measured surface - means a representation of the surface obtained by instrumental
or other means.
Nominal profile - means a profile of the nominal surface; it is the intended profile
(exclusive of any intended roughness profile). Nominal surface - means the intended surface contour (exclusive of any intended
surface roughness), the shape and extent of which is usually shown and dimensioned on a drawing or descriptive specification.
Peak - means the point of maximum height on that portion of a profile that lies
above the centerline and between two intersections of the profile with the centerline.
Roughness - means the finer irregularities of surface texture, usually including those irregularities which result from the inherent action of the production process. These are considered to include traverse feed marks and other irregularities within the limits of the roughness sampling length.
Roughness sampling length - means the sampling length within which the
roughness average is determined. This length is chosen, or specified, to separate the
profile irregularities which are designated as roughness from those irregularities
designated as waviness.
Roughness spacing - means the average spacing between adjacent peaks of the measured profile within the roughness sampling length.
Sampling length - means the nominal spacing within which a surface characteristic is determined. Spacing - means the distance between specified points on the profile measured
parallel to the nominal profile.
Surface texture - means the repetitive of random deviations from the nominal surface which form the three-dimensional topography of the surface. Surface texture
includes roughness, waviness, lay and flaws.
Valley - means the point of maximum depth on that portion of a profile that lies
below the centerline and between two intersections of the profile with the centerline.
Waviness - means the more widely spaced component of surface texture. Unless otherwise noted, waviness is to include all irregularities whose spacing is greater than the
roughness sampling length and less than the waviness sampling length. Waviness may
result from such factors as machine or work deflections, vibration, chatter, heat-treatment or warping strains. Roughness may be considered as being superposed on a 'wavy'
surface.
Waviness spacing - means the average spacing between adjacent peaks of the
measured profile within the waviness sampling length.
These definitions are based on American National Standard ANSI B46.1-1985. Frosted Haptic Portions
A plate-type deformable intraocular lens 10 according to the present invention is
shown in Fig. 1. The deformable intraocular lens 10 comprises a lens portion 12 and
haptic portion 14 including haptic portions 14a and 14b. The haptic portions 14a and 14b
are provided with frosted surface portions 16a and 16b, respectively. As shown in Figs.
2 and 3, both sides of the haptic portions 14a and 14b are provided with frosted surface
portions 16a and 16b, respectively.
Colored Haptic Portions
Another embodiment of a deformable intraocular lens 20 according to the present
invention is shown in Fig. 6. The intraocular lens 20 includes a lens portion 22 and haptic
portion 24, including haptic portions 24a and 24b. The haptic portions 24a and 24b are
provided with colored or tinted portions 26a and 26b, respectively.
The colored portions 24a and 24b can be made by coloring, dying, painting,
masking, coating, tinting or other suitable process of applying a coloring material to the
interior and/or surface of the haptic portion. The coloring material can be added to the
lens material (e.g., before or during formation of the lens), or used to treat the lens
material (e.g., dying surface, coating surface, modifying surface or interior with radiation
after formation of the lens). The coloring material can be of a type to leave the haptic material transparent with coloring (e.g., tinting), or can be of a type to make the haptic material opaque (e.g., color pigment or dye).
Surface Frosting and/or Texturing
The frosted and/or textured surface portions of the haptics are provided by forming or making portions of the haptic having a particular surface roughness.
Specifically, the roughness of a surface is based on the dimensional aspects of gaps and protrusions in the surface of the haptics. The surface roughness can be further
characterized by the mean value of the width of the gaps, the mean value of the thickness of the protrusions, the mean value of the depth of the gaps, and the mean value of the
spacing between the gaps. This manner of characterizing surface roughness in the context
of an intraocular lens is set forth in U.S. Patent 5,405,385 to Heimke et al. U.S. Patent
5,405,385 is fully incorporated by reference herein.
The desired extent of frosting of the frosted surface portions of the haptic portions
in the IOLs according to the present invention is to preferably provide a mean value of the
width of the gaps of from 8-128 microns, a mean value of thickness of the protrusions of from 8-128 microns, a mean value of the depth of the gaps of 8-128 microns, and a mean value of spacing between gaps in a range of 8-128 microns. These parameters will be
referred to in general as the mean surface roughness. The mean surfaces roughness is the
average of the mean values of width of the gaps, mean value of thickness of the
protrusions, and mean value of the depth of the gaps. More preferably, the mean value of width of the gaps is from 16-64 microns, the mean value of the thickness of the protrusions is from 16-64 microns, the mean value of the depth of the gaps is 16-64 microns, and the mean value of the spacing between gaps is 16-64 microns. The most
preferred surface roughness is characterized by a mean value of width of the gaps of 32
microns, a mean value of the thickness of the protrusions of 32 microns, the mean value
of the depths of the gaps of 32 microns, and the mean value of the spacing between the gaps of 32 microns.
Example
A one-piece plate-type deformable intraocular lens according to the present
invention was made by the following technique, and is shown in Figs. 10 and 11. The
deformable IOL shown in Figure 10 was made by injection molding standard silicon polymer material in a metal mold, followed by tumble polishing.
The metal mold was prepared by electro discharge machining (EDM) to cut the
mold cavity. The lens portion and inner portions of the haptics were then highly polished
to finalize the mold while the portions to mold the frosted haptic portions were left
roughened. The lens was then molded by conventional molding techniques for manufacturing the silicon deformable intraocular lens.

Claims

We Claim:
1. A deformable intraocular lens, comprising:
a lens portion; and
a haptic portion, said haptic portion including a frosted portion.
2. A lens according to Claim 1, wherein one side of said haptic portion is frosted.
3. A lens according to Claim 1 , wherein both sides of said haptic portion are frosted.
4. A lens according to Claim 1, wherein an entire surface of said haptic portion is frosted.
5. A lens according to Claim 1, wherein a portion less than an entire surface of said
haptic portion is frosted.
6. A lens according to Claim 1, wherein said frosted portion is preferably defined by
a mean surface roughness in the range of 8 to 128 microns.
7. A lens according to Claim 6, wherein said mean surface roughness is preferably
defined by a mean surface roughness in the range of 16 to 64 microns.
8. A lens according to Claim 7, wherein said mean surface roughness is most
preferably about 32 microns.
9. A lens according to Claim 1, wherein at least a portion of said haptic portion is
colored.
10. A lens according to Claim 1, wherein at least a portion of said haptic portion is
translucent.
11. A lens according to Claim 10, wherein at least a portion of said haptic portion is
translucent.
12. A lens according to Claim 1, wherein at least a portion of said haptic is opaque.
13. A lens according to Claim 9, wherein at least a portion of said haptic is opaque.
14. A lens according to Claim 10, wherein at least a portion of said haptic is opaque.
15. A lens according to Claim 11, wherein at least a portion of said haptic is
opaque. AMENDED CLAIMS
[received by the International Bureau on 01 April 1999 (01.04.99); original claims 11 and 15 cancelled; original claims 1,2,3,4,5,9,10,12,13 and 14amended; new claims 16-27 added (4 pages)]
1. (amended) A plate-type deformable intraocular lens, comprising: a lens portion; and
a pair of oppositely disposed plate-type haptic [portion] portions, said haptic [portion] portions including a frosted portion,
2. (amended) A lens according to Claim I, wherein one side of said haptic [portion] portions is frosted.
3. (amended) A lens according to Claim 1, wherein both sides of said haptic [portion] portions are frosted.
4. (amended) A lens according to Claim 1 , wherein an entire surface of said haptic [portion] portions is frosted.
5. (amended) A lens according to Claim 1, wherein a portion less than an entire surface of said haptic [portion] portions is frosted,
6. A lens according to Claim 1 , wherein said frosted portion is preferably defined by a mean surface roughness in the range of 8 to 128 microns.
7. A lens according to Claim 6, wherein said mean surface roughness is preferably defined by a mean surface roughness in the range of 16 to 64 microns,
8. A lens according to Claim 7, wherein said mean surface roughness is most preferably about 32 microns.
9. (amended) A lens according to Claim 1, wherein at least a portion of said haptic [portion] portions is colored.
10. (amended) A lens according to Claim 1 , wherein at least a portion of said haptic [portion] portions is translucent.
11. Cancel.
12. (amended) A lens according to Claim 1, wherein at least a [portion] portions of said haptic is opaque.
13. (amended) A lens according to Claim 9, wherein at least a [poπion] portions of said haptic is opaque.
14. (amended) A lens according to Claim 10, wherein at least a [portion] portions of said haptic is opaque.
IS. Cancel,
.
16. A deformable intraocular lens, comprising:
a lens portion, and
a haptic portion, said haptic portion including a frosted portion wherein said frosted portion is defined by a mean surface roughness in the range of 8 to 128 microns,
17. A lens according to Claim 16. wherein one side of said haptic portion is frosted.
18. A lens according to Claim 16. wherein both side of said haptic portion are frosted.
1 . A lens according to Claim 16. wherein an entire surface of said haptic portion is frosted.
20. A lens according to Claim 16. wherein a portion less than an entire surface of said haptic portion is frosted,
2L A lens according to Claim 16. wherein said mean surface roughness is defined by a mean surface roughness in the range of 16 to 64 microns.
22. A lens according to Claim 21. wherein said mean surface roughness is about 32 microns.
2J . A lens according to Claim 16. wherein at least a portion of said haptic portion is colored,
24. A lens according to Claim 1 . wherein at least a portion of said haptic portion is trangtøpent
2-- A lens according to Claim 16. wherein at least a portion of said haptic is opaque,
26, A lens according to Claim 23. wherein at least a portion of said haptic is opaque.
27. A lens according to Claim 24. wherein at least a portion of said haptic is opaque.
PCT/US1998/025718 1997-12-10 1998-12-10 Frosted haptic intraocular lens WO1999029265A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002313334A CA2313334A1 (en) 1997-12-10 1998-12-10 Frosted haptic intraocular lens
KR1020007006368A KR100602461B1 (en) 1997-12-10 1998-12-10 Frosted haptic intraocular lens
AU18033/99A AU759433B2 (en) 1997-12-10 1998-12-10 Frosted haptic intraocular lens
EP98962893A EP1039850A4 (en) 1997-12-10 1998-12-10 Frosted haptic intraocular lens
JP2000523943A JP2001525219A (en) 1997-12-10 1998-12-10 Intraocular lens with matte antenna

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Application Number Priority Date Filing Date Title
US08/988,185 US6129759A (en) 1997-12-10 1997-12-10 Frosted haptic intraocular lens
US08/988,185 1997-12-10

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WO1999029265A1 true WO1999029265A1 (en) 1999-06-17
WO1999029265A8 WO1999029265A8 (en) 1999-09-02

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Also Published As

Publication number Publication date
AU759433B2 (en) 2003-04-17
KR20010033015A (en) 2001-04-25
US6537316B1 (en) 2003-03-25
CN1285722A (en) 2001-02-28
AU1803399A (en) 1999-06-28
EP1039850A4 (en) 2001-05-16
WO1999029265A8 (en) 1999-09-02
EP1039850A1 (en) 2000-10-04
CA2313334A1 (en) 1999-06-17
KR100602461B1 (en) 2006-07-19
US6129759A (en) 2000-10-10
JP2001525219A (en) 2001-12-11

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