WO1999042167A3 - Intravascular radiation delivery system - Google Patents

Intravascular radiation delivery system Download PDF

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Publication number
WO1999042167A3
WO1999042167A3 PCT/US1998/000463 US9800463W WO9942167A3 WO 1999042167 A3 WO1999042167 A3 WO 1999042167A3 US 9800463 W US9800463 W US 9800463W WO 9942167 A3 WO9942167 A3 WO 9942167A3
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
radiation
balloon
lumen
radiation source
Prior art date
Application number
PCT/US1998/000463
Other languages
French (fr)
Other versions
WO1999042167A2 (en
Inventor
Roger N Hastings
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc filed Critical Scimed Life Systems Inc
Priority to EP98903431A priority Critical patent/EP1011787A4/en
Priority to CA002277856A priority patent/CA2277856A1/en
Priority to JP53494099A priority patent/JP2002513322A/en
Publication of WO1999042167A2 publication Critical patent/WO1999042167A2/en
Publication of WO1999042167A3 publication Critical patent/WO1999042167A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0127Magnetic means; Magnetic markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M2025/0177Introducing, guiding, advancing, emplacing or holding catheters having external means for receiving guide wires, wires or stiffening members, e.g. loops, clamps or lateral tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1047Balloon catheters with special features or adapted for special applications having centering means, e.g. balloons having an appropriate shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1095Balloon catheters with special features or adapted for special applications with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • A61N2005/1003Intraluminal radiation therapy having means for centering a radioactive source within the lumen, e.g. balloons

Abstract

This invention is an intravascular radiation delivery system (10) including a catheter (11), a radiation source (14), disposed in an open-ended lumen (12) in the catheter (11), and a closed-ended sheath (13) surrounding the radiation source (14), so as to prevent blood and other fluids from coming into contact with the radiation source (14). Preferably, the open-ended lumen (12) is centered in the balloon (15) for uniform radiation delivery. The catheter (11) may include a blood perfusion lumen under the balloon (15) or around the balloon (15). The open-ended lumen (12) in the catheter (11) may have a reduced diameter adjacent the distal end of the catheter (11) to prevent the radiation source (14) from exiting the lumen. Methods of using the radiation delivery system (10) are also disclosed, such as an alternative method of delivering radiation to a treatment site inside the vasculature of a patient using a gas-filled balloon catheter and a radiation source disposed in the balloon catheter. The treatment site is exposed to radiation, preferably beta radiation, through the gas-filled balloon.
PCT/US1998/000463 1997-01-10 1998-01-07 Intravascular radiation delivery system WO1999042167A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP98903431A EP1011787A4 (en) 1997-01-10 1998-01-07 Intravascular radiation delivery system
CA002277856A CA2277856A1 (en) 1997-01-10 1998-01-07 Intravascular radiation delivery system
JP53494099A JP2002513322A (en) 1997-01-10 1998-01-07 Intravascular radiation delivery system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/782,471 1997-01-10
US08/782,471 US6234951B1 (en) 1996-02-29 1997-01-10 Intravascular radiation delivery system

Publications (2)

Publication Number Publication Date
WO1999042167A2 WO1999042167A2 (en) 1999-08-26
WO1999042167A3 true WO1999042167A3 (en) 2004-04-22

Family

ID=25126159

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/000463 WO1999042167A2 (en) 1997-01-10 1998-01-07 Intravascular radiation delivery system

Country Status (5)

Country Link
US (3) US6234951B1 (en)
EP (1) EP1011787A4 (en)
JP (1) JP2002513322A (en)
CA (1) CA2277856A1 (en)
WO (1) WO1999042167A2 (en)

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US6582353B1 (en) 2003-06-24
US20010023308A1 (en) 2001-09-20
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US6599230B2 (en) 2003-07-29

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