WO1999060869A8 - Sitostanol formulation with emulsifier to reduce cholesterol absorption - Google Patents

Sitostanol formulation with emulsifier to reduce cholesterol absorption

Info

Publication number
WO1999060869A8
WO1999060869A8 PCT/US1999/006293 US9906293W WO9960869A8 WO 1999060869 A8 WO1999060869 A8 WO 1999060869A8 US 9906293 W US9906293 W US 9906293W WO 9960869 A8 WO9960869 A8 WO 9960869A8
Authority
WO
WIPO (PCT)
Prior art keywords
cholesterol absorption
reduce cholesterol
sitostanol
emulsifier
compositions
Prior art date
Application number
PCT/US1999/006293
Other languages
French (fr)
Other versions
WO1999060869A1 (en
Inventor
Richard E Ostlund Jr
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22185744&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1999060869(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to HU0302902A priority Critical patent/HUP0302902A3/en
Priority to CA002332983A priority patent/CA2332983C/en
Priority to PL99377965A priority patent/PL193796B1/en
Priority to EP99914986A priority patent/EP1082029B1/en
Priority to AU33609/99A priority patent/AU762738B2/en
Application filed by Univ Washington filed Critical Univ Washington
Priority to PL345163A priority patent/PL191389B1/en
Priority to JP2000550344A priority patent/JP3755064B2/en
Priority to DE69939315T priority patent/DE69939315D1/en
Priority to BR9910719-8A priority patent/BR9910719A/en
Publication of WO1999060869A1 publication Critical patent/WO1999060869A1/en
Publication of WO1999060869A8 publication Critical patent/WO1999060869A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Abstract

Compositions useful to reduce cholesterol absorption. The compositions may be dosed in capsule or tablet form, or by adding either in liquid or dry powder form to foods and beverages. The compositions are an aqueous based homogeneous micellar mix which is dried to provide a mixture of finely-divided plant sterol, preferably sitostanol and lecithin. The mole ratio of the plant sterol, preferably sitostanol to lecithin, should be within the range of 1:0.1 to 1:10, preferably at least 1:2.
PCT/US1999/006293 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption WO1999060869A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
BR9910719-8A BR9910719A (en) 1998-05-26 1999-03-25 Formulation of sitostanol with emulsifier to reduce cholesterol absorption
CA002332983A CA2332983C (en) 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption
PL99377965A PL193796B1 (en) 1999-03-25 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same
EP99914986A EP1082029B1 (en) 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption
AU33609/99A AU762738B2 (en) 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption
HU0302902A HUP0302902A3 (en) 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption
PL345163A PL191389B1 (en) 1998-05-26 1999-03-25 Sitostand formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same
JP2000550344A JP3755064B2 (en) 1998-05-26 1999-03-25 Emulsifier-containing sitostanol preparations to reduce cholesterol absorption
DE69939315T DE69939315D1 (en) 1998-05-26 1999-03-25 SITOSTANOL CONTAINING AN EMULSIFIER PREPARED TO REDUCE CHOLESTERINE ABSORPTION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/084,561 US5932562A (en) 1998-05-26 1998-05-26 Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
US09/084,561 1998-05-26

Publications (2)

Publication Number Publication Date
WO1999060869A1 WO1999060869A1 (en) 1999-12-02
WO1999060869A8 true WO1999060869A8 (en) 2001-07-19

Family

ID=22185744

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/006293 WO1999060869A1 (en) 1998-05-26 1999-03-25 Sitostanol formulation with emulsifier to reduce cholesterol absorption

Country Status (13)

Country Link
US (1) US5932562A (en)
EP (1) EP1082029B1 (en)
JP (1) JP3755064B2 (en)
AT (1) ATE404076T1 (en)
AU (1) AU762738B2 (en)
BR (1) BR9910719A (en)
CA (1) CA2332983C (en)
CZ (1) CZ299194B6 (en)
DE (1) DE69939315D1 (en)
ES (1) ES2310034T3 (en)
HU (1) HUP0302902A3 (en)
PL (1) PL191389B1 (en)
WO (1) WO1999060869A1 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0897970B1 (en) * 1997-08-22 2004-09-29 Unilever N.V. Process for the production of stanol esters
US6312703B1 (en) 1998-02-06 2001-11-06 Lecigel, Llc Compressed lecithin preparations
US6110502A (en) * 1998-02-19 2000-08-29 Mcneil-Ppc, Inc. Method for producing water dispersible sterol formulations
US6063776A (en) * 1998-05-26 2000-05-16 Washington University Sitostanol formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same
CA2334449A1 (en) * 1998-06-05 1999-12-16 Radka K. Milanova Compositions comprising phytosterol, phytostanol or mixtures of both having enhanced solubility and dispersability and incorporation thereof into foods, beverages, pharmaceuticals, nutraceuticals and the like
US6123978A (en) * 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6376481B2 (en) * 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6242001B1 (en) 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
US6503478B2 (en) 1999-01-13 2003-01-07 Lightouch Medical, Inc. Chemically specific imaging of tissue
EP1146798A2 (en) * 1999-01-15 2001-10-24 Nutrahealth Ltd. (UK) Modified food products and beverages, and additives for food and beverages
US6190720B1 (en) * 1999-06-15 2001-02-20 Opta Food Ingredients, Inc. Dispersible sterol compositions
WO2001000046A1 (en) * 1999-06-25 2001-01-04 Cognis Deutschland Gmbh Use of nanoscale sterols and sterol esters
US6391370B1 (en) * 1999-11-12 2002-05-21 Kraft Foods, Inc. Micromilling plant sterols and emulsifiers
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
EP1274319B1 (en) * 2000-04-14 2009-08-12 Mars, Incorporated Compositions and methods for improving vascular health
US7147859B2 (en) * 2000-05-15 2006-12-12 Laboratorios Biosintetica Ltda. Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers
BR0001794A (en) * 2000-05-15 2001-12-26 Laboratorios Biosintetica Ltda Application of phytosteroids (and their isomers), folic acid, cyanocobalamin and pyridoxine in dietary fibers (food)
KR20020026053A (en) 2000-09-30 2002-04-06 노승권 Method of dispersing plant sterol for a beverage and beverage containing the same
US20020107232A1 (en) * 2001-01-12 2002-08-08 Flickinger Brent D. Methods for producing sterol ester-rich compositions
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DE60234120D1 (en) * 2001-11-16 2009-12-03 Univ Brandeis FINISHED FOODS CONTAINING TRUCLYCERIDES OF RE-RISKED NON-ESTERED PHYTOSTEROLS
US7144595B2 (en) 2001-11-16 2006-12-05 Brandeis University Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
CN1297216C (en) * 2002-03-20 2007-01-31 尤金科学(有限)公司 Mixing powder of plant sterol and emulsifier, and method for preparing the same
WO2003077679A1 (en) * 2002-03-20 2003-09-25 Eugene Science Inc. Plant sterol-containing food, and method for preparing the same
US7368138B2 (en) * 2002-03-21 2008-05-06 Archer-Daniels-Midland Company Extraction of phytosterols from corn fiber using green solvents
US7514107B2 (en) 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
WO2003086108A1 (en) * 2002-04-10 2003-10-23 Archer-Daniels-Midland Company Hydrothermically processed compositions containing phytosterols
US20040033903A1 (en) * 2002-05-02 2004-02-19 Volker Kuellmer Coated, agglomerated phytochemicals
US20030212046A1 (en) * 2002-05-07 2003-11-13 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
US20060093661A1 (en) 2002-05-07 2006-05-04 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
EP1511468A1 (en) * 2002-06-10 2005-03-09 Elan Pharma International Limited Nanoparticulate sterol formulations and sterol combinations
US20040047946A1 (en) * 2002-09-10 2004-03-11 Kapac, Llc Methods and formulations useful for lowering the cholesterol content of egg yolk
US20070003600A1 (en) * 2003-06-11 2007-01-04 Carolyn Moore Methods for reducing c-reactive protein
US7595077B2 (en) * 2003-10-31 2009-09-29 Q.P. Corporation Complex
US20080274195A1 (en) 2005-07-18 2008-11-06 University Of Massachusetts Lowell Compositions and Methods for Making and Using Nanoemulsions
US20070026126A1 (en) * 2005-08-01 2007-02-01 Bryan Hitchcock Sterol fortified beverages
DE102005039835A1 (en) * 2005-08-23 2007-03-01 Cognis Ip Management Gmbh Powdered sterol formulations with colloid formers
US7575768B2 (en) * 2005-09-07 2009-08-18 Brandeis University Dietary supplements and prepared foods containing triglyceride-recrystallized non-esterified phytosterols
US7601380B2 (en) * 2005-11-17 2009-10-13 Pepsico, Inc. Beverage clouding system and method
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
PT3144013T (en) 2005-12-01 2019-02-07 Univ Massachusetts Lowell Botulinum nanoemulsions
US7678399B2 (en) 2005-12-05 2010-03-16 Bunge Oils, Inc. Phytosterol containing deep-fried foods and methods with health promoting characteristics
US8309156B2 (en) * 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
JP2009521416A (en) * 2005-12-20 2009-06-04 フォーブス メディ−テック インコーポレーテッド Emulsion containing unesterified phytosterol in aqueous phase
KR20090006051A (en) * 2005-12-20 2009-01-14 포비스 메디-테크 인코포레이티드 Compositions comprising one or more phytosterols and/or phytostanols, or deriva-tives thereof, and high hlb emulsifiers
US20080124387A1 (en) 2006-11-27 2008-05-29 Kapac, Llc Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients
US20100150994A1 (en) 2006-12-01 2010-06-17 Anterios, Inc. Amphiphilic entity nanoparticles
CA2671133C (en) * 2006-12-01 2015-11-24 Anterios, Inc. Peptide nanoparticles and uses therefor
JP4029110B1 (en) * 2006-12-26 2008-01-09 タマ生化学株式会社 Composition of plant sterol and phosphatidylcholine and method for producing the same
CN101765423B (en) 2007-05-31 2014-08-06 安特里奥公司 Nucleic acid nanoparticles and uses therefor
US20090088393A1 (en) * 2007-09-28 2009-04-02 Zomanex, Llc Methods and formulations for converting intravenous and injectable drugs into oral dosage forms
US7790495B2 (en) * 2007-10-26 2010-09-07 International Business Machines Corporation Optoelectronic device with germanium photodetector
SE532965C2 (en) * 2008-02-06 2010-05-25 Edio Healthcare Ab Process for the preparation of plant sterol microparticles
CL2009000409A1 (en) * 2009-02-23 2009-05-04 Rojas Alejandro Markovits Process to obtain a dispersion of solid phytosterols in water.
US20110223312A1 (en) * 2009-11-30 2011-09-15 Daniel Perlman Triglyceride-encapsulated phytosterol microparticles dispersed in beverages
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
JP6316182B2 (en) 2014-12-19 2018-04-25 富士フイルム株式会社 Liposome production method and liposome production apparatus
BR112019010131A2 (en) 2016-11-21 2019-10-08 Eirion Therapeutics Inc transdermal delivery of large agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881005A (en) * 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
DE2400518A1 (en) * 1974-01-07 1975-07-10 Ritter & Co D Atherosclerotic dietary compsn - contains lecithin and beta-sitosterin to reduce cholesterol levels
FR2521565B1 (en) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian PULVERULENT MIXTURE OF LIPID COMPONENTS AND HYDROPHOBIC CONSTITUENTS, METHOD FOR PREPARING SAME, HYDRATED LIPID LAMELLAR PHASES AND MANUFACTURING METHOD, PHARMACEUTICAL OR COSMETIC COMPOSITIONS COMPRISING HYDRATED LAMID PHASES
JP2885430B2 (en) * 1989-08-16 1999-04-26 旭松食品株式会社 Frozen tofu
DE4038385C2 (en) * 1990-12-01 1998-09-17 Hoyer Gmbh & Co Kg Sitosterol and its glycosides with improved bioavailability
US5244887A (en) * 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof

Also Published As

Publication number Publication date
CA2332983C (en) 2006-03-07
EP1082029B1 (en) 2008-08-13
PL191389B1 (en) 2006-05-31
AU3360999A (en) 1999-12-13
HUP0302902A2 (en) 2004-01-28
PL345163A1 (en) 2001-12-03
HUP0302902A3 (en) 2005-10-28
ATE404076T1 (en) 2008-08-15
US5932562A (en) 1999-08-03
WO1999060869A1 (en) 1999-12-02
JP2002516260A (en) 2002-06-04
CZ299194B6 (en) 2008-05-14
BR9910719A (en) 2001-01-09
DE69939315D1 (en) 2008-09-25
EP1082029A1 (en) 2001-03-14
AU762738B2 (en) 2003-07-03
JP3755064B2 (en) 2006-03-15
CA2332983A1 (en) 1999-12-02
CZ20004400A3 (en) 2001-11-14
ES2310034T3 (en) 2008-12-16

Similar Documents

Publication Publication Date Title
WO1999060869A8 (en) Sitostanol formulation with emulsifier to reduce cholesterol absorption
BR0314994A (en) Cream compositions and methods of manufacture and use thereof
CA2395331A1 (en) Pharmaceutical compositions providing enhanced drug concentrations
AU2317399A (en) Cereal products with inulin and methods of preparation
AU1765088A (en) Use of parenchymal cell cellulose to improve comestibles
MY114641A (en) Fortification of foodstuff
JPS5659710A (en) Preventive and remedy for psoriasis
CA2239760A1 (en) Process for the manufacture of milk powder, a dietetic formula, a culinary product or a coffee base
CA2312076A1 (en) A method for preparation of mulberry leaf powder and ice cream containing thereof
SE7906467L (en) HYPO-BETA-LIPOPROTEINEMIC DIETIC, PROCEDURES FOR PREPARING IT AND USING IT
EP0609465A4 (en) Custard cream.
JPS55150845A (en) Preparation of fat and oil powder
KR880007116A (en) Powdered emulsifiers, preparation methods and uses
JPS6456622A (en) Percutaneous absorbefacient base composition
DE69723793D1 (en) Foam dish and process for its preparation, premix therefor, and process for the preparation of this premix
GB1459407A (en) Active dried yeast
CN109924503A (en) A kind of functionality linseed oil compound powder and preparation method thereof
KR950007680A (en) Hard Candy Compositions and Manufacturing Method Thereof
Chung et al. Properties of cookies made of flour and Chinese yam powder
IE892632L (en) Mousse product
AU4346200A (en) Alkanolamide surfactant emulsions and process therefor
JPS60178882A (en) Powdery composition of solubilized vitamine
KR950016541A (en) Healthy tea and its manufacturing method
JPS56158064A (en) Preparation of food like chinese noodle
KR970064416A (en) Rice flour and its preparation method

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref document number: 2332983

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 33609/99

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: PA/a/2000/011537

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 1999914986

Country of ref document: EP

Ref document number: PV2000-4400

Country of ref document: CZ

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 550344

Kind code of ref document: A

Format of ref document f/p: F

WWP Wipo information: published in national office

Ref document number: 1999914986

Country of ref document: EP

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)

Free format text: (EXCEPT BR, CZ, HU, MX, PL)

AK Designated states

Kind code of ref document: C1

Designated state(s): AU BR CA CZ HU JP MX PL

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT. BUL. 48/99 UNDER (81) ADD "BR, CZ, HU, MX, PL"; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWP Wipo information: published in national office

Ref document number: PV2000-4400

Country of ref document: CZ

WWG Wipo information: grant in national office

Ref document number: 33609/99

Country of ref document: AU